Hub : Genes

AC007098.1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Cells Transformed fibroblasts 0.0760 0.0340 0.0045 -0.002 NA 0.011 NA -0.003 0.4700 NA 0.044 NA 0.780
2 GTEx Nerve Tibial 0.0481 0.0284 0.0083 0.023 NA 0.008 NA 0.017 0.0091 NA 0.086 NA 0.021

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.7 1.1 1.9 1.4 0.5
Bipolar Disorder or Schizophrenia 1.9 4.7 5.8 1.9 2.4
Depressed Affect (Nagel 2018) 2.0 4.2 7.1 -2.7 1.1
Depression (Nagel 2018) 0.9 1.4 1.6 -1.1 1.3
Intelligence (Savage-Jansen 2018) 2.5 7.6 14.7 0.8 -3.8
Neuroticism (Nagel 2018) 1.9 4.5 5.4 -2.3 1.9
Schizophrenia (2018) 2.1 4.4 7.4 1.2 2.7
Schizophrenia vs Biploar Disorder 1.0 1.4 2.1 -0.8 1.4
Worry (Nagel 2018) 2.2 4.7 6.2 -2.5 1.8
Alzheimer’s Disease (in mother) 1.8 2.2 3.9 -0.6 -2.0
Alzheimer’s Disease (in father) 1.7 1.9 1.9 -1.4 1.4
Alzheimer’s Disease (including proxy) 1.0 1.4 2.2 -1.5 -0.8
Crohns Disease (2017) 0.4 1.0 1.3 -0.8 1.2
Irritable Bowel Disease (IBD) 0.2 0.5 0.7 -0.5 0.9
Ulcerative Colitis (UC) 0.1 0.2 0.4 0.1 0.6
Major Depression (MDD) 0.3 0.3 0.6 -0.2 0.8
Reaction Time 0.3 0.6 1.1 1.1 -0.3
Verbal and Numeric Reasoning (VNR) 3.7 8.8 16.5 1.1 -4.1
Breast Cancer 0.2 0.6 1.1 -1.1 0.2
Ovarian Cancer 0.2 0.3 0.4 -0.5 0.6
Prostate Cancer 24.5 34.5 53.1 4.0 -7.3
Age at First Birth 0.4 0.5 1.0 1.0 0.1
Bipolar Disorder (2011) 1.1 1.1 2.1 -0.1 1.5
Body Mass Index (BMI) (2010) 1.9 2.5 4.6 0.7 -2.2
Coronary Artery Disease (CAD) 0.4 0.5 0.9 0.1 -1.0
Crohns Disease (2012) 1.5 2.4 4.8 -2.2 -0.3
Mean Putamen Volume 0.7 0.8 1.4 -0.4 -1.2
Fasting Glucose 0.4 0.5 0.5 -0.7 0.6
HbA1C 0.7 0.8 1.4 -1.2 -0.3
HDL Cholesterol 0.1 0.1 0.2 0.4 0.3
LDL Cholesterol 3.8 5.9 10.9 1.0 -3.3
Lupus 0.1 0.1 0.1 -0.3 -0.3
Neuroticism (2016) 3.2 4.7 7.4 -1.4 2.7
Primary Biliary Cirrhosis 0.1 0.2 0.4 -0.2 -0.6
Rheumatoid Arthritis 0.8 1.1 1.3 0.9 -1.1
Schizophrenia (2014) 2.4 5.3 8.1 1.6 2.8
Triglycerides 0.0 0.1 0.1 0.0 -0.3
Type 2 Diabetes (T2D) (2012) 2.0 2.3 2.9 1.7 -1.3
Ulcerative Colitis 0.5 0.7 1.4 -1.2 0.3
Blood Eosinophil Count 0.2 1.7 2.2 1.5 -1.1
Blood Platelet Count 0.4 4.3 8.5 0.3 -2.9
Blood Red Count 0.1 0.5 1.0 0.1 1.0
Blood White Count 0.0 0.3 0.5 -0.1 -0.7
Heel T-Score 0.1 0.7 1.3 -1.1 -0.4
BMI 1.9 10.9 13.0 3.0 -3.6
Height 0.0 0.3 0.5 0.7 0.4
Waist Hip Ratio (WHR) 0.5 2.2 4.4 2.1 0.1
Systolic Blood Pressure 0.1 0.5 0.7 -0.8 0.5
Smoking Status 2.9 6.9 11.2 -1.6 3.3
Allergy or Eczema 0.6 1.7 2.1 1.4 -1.1
Cardiovascular Disease 0.5 1.6 2.2 1.0 -1.5
Hypothyroidism (self reported) 1.1 2.4 4.0 0.9 2.0
Respiratory disease 1.5 3.3 5.9 2.4 -0.8
Type 2 Diabetes (T2D) (2018) 1.2 2.3 4.5 0.3 -2.1
Lung FEV1/FVC ratio 0.5 2.3 3.3 -1.1 1.8
Lung FVC 2.6 13.4 19.4 -2.7 4.4
Neuroticism 3.3 7.9 8.6 -2.7 2.9
Chronotype (morning person) 2.6 6.0 6.8 2.3 2.6
Hair Pigment 0.1 1.9 3.5 1.9 0.6
Tanning 1.4 17.4 25.7 -5.1 3.0
Hand grip strength (left) 0.5 1.2 2.3 -1.5 0.3
Number of treatments/medications taken 0.7 1.3 2.4 -0.4 1.6
Average weekly spirits intake 0.5 0.6 0.7 -0.7 0.8
Sensitivity / hurt feelings 0.2 0.4 0.6 -0.4 -0.8
Frequency of depressed mood in last 2 weeks 1.7 2.4 2.6 -1.5 1.6
Hearing difficulty/problems: Yes 0.7 1.1 1.6 1.3 -0.7
Relative age of first facial hair 2.7 5.5 10.2 0.9 3.2
Other serious medical condition/disability diagnosed by doctor 5.7 7.3 7.6 2.7 -2.8
Ever used hormone-replacement therapy (HRT) 0.4 0.5 1.1 -1.0 -0.0
Ever had hysterectomy (womb removed) 0.4 0.5 0.5 0.7 0.6
Systolic blood pressure, automated reading 0.4 1.1 1.7 -1.3 -0.6
Eye problems/disorders: Diabetes related eye disease 0.2 0.2 0.3 0.5 -0.5
Angina 1.4 1.9 2.6 1.1 -1.6
Medication for hormone replacement therapy 3.3 3.6 7.2 -0.2 2.7
Vitamin and mineral supplements 2.2 2.9 5.8 -0.2 -2.4
Supplements: Zinc 3.3 3.6 6.7 -0.8 2.6
Medication: Co-codamol 0.6 0.6 1.2 0.2 1.1
Medication: Metformin 2.1 3.0 5.7 0.6 -2.4
Diabetes (father) 1.0 1.3 2.1 1.4 -0.7
Diabetes (mother) 0.4 0.5 0.8 0.3 -0.9
Severe depression (siblings) 0.6 0.7 1.1 1.1 0.5
Pack years adult smoking proportion 0.2 0.3 0.4 0.5 0.7
Impedance of leg (right) 1.8 8.5 16.7 -0.6 4.1
Leg fat-free mass (left) 1.6 8.4 12.3 2.1 -3.5
Trunk fat percentage 1.5 5.9 7.0 2.2 -2.6
Hand grip strength (right) 0.5 1.3 2.5 -0.2 -1.6
Townsend deprivation index at recruitment 0.7 1.0 1.1 -0.9 1.0
Current tobacco smoking 0.9 1.5 2.0 -0.9 1.4
Average weekly fortified wine intake 1.4 1.7 2.2 1.1 1.5
Maternal smoking around birth 1.3 1.8 3.2 -0.6 1.8
Fed-up feelings 1.5 2.7 5.1 -2.2 0.6
Frequency of unenthusiasm / disinterest in last 2 weeks 2.0 2.6 5.0 -0.5 2.2
Relative age voice broke 0.6 1.0 1.6 1.3 0.6
Taking other prescription medications 0.3 0.4 0.8 0.1 0.9
Age when periods started (menarche) 0.8 1.8 3.1 -0.7 -1.8
Bilateral oophorectomy (both ovaries removed) 0.2 0.2 0.3 -0.4 0.5
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.2 0.3 0.5 0.4
Tinnitus: Yes, but not now, but have in the past 0.4 0.5 1.0 0.0 -1.0
Qualifications: CSEs or equivalent 0.4 0.5 0.7 0.8 0.6
Serious illness, injury or assault to yourself 0.5 0.6 0.9 0.6 -0.9
High blood pressure 0.0 0.0 0.0 0.1 0.1
Hayfever, allergic rhinitis or eczema 0.6 1.3 1.6 1.0 -1.3
Multivitamins +/- minerals 1.7 2.1 4.2 -0.2 2.1
Stomach or abdominal pain in last month 1.6 2.0 2.4 1.2 1.6
Supplements: Glucosamine 1.0 1.2 2.5 0.2 1.6
Diverticular disease/diverticulitis (self-reported) 0.4 0.5 0.9 0.9 0.2
Medication: Atenolol 2.2 2.8 2.8 1.7 -1.7
Medication: Levothyroxine sodium 1.4 2.4 2.5 1.6 1.5
Sitting height 0.2 1.6 2.7 0.7 -1.6
Chronic bronchitis/emphysema (father) 0.2 0.3 0.6 -0.8 -0.1
High blood pressure (mother) 1.3 1.8 3.1 1.8 0.7
Body mass index (BMI) 2.4 10.1 14.4 2.4 -3.8
Impedance of leg (left) 1.4 6.7 13.3 -0.3 3.6
Leg predicted mass (left) 1.5 8.2 11.8 2.1 -3.4
Trunk fat mass 1.9 8.2 9.9 2.5 -3.1
Waist circumference 3.5 13.0 13.2 3.6 -3.6
Number of incorrect matches in round 0.3 0.5 0.9 0.3 0.9
Past tobacco smoking 1.6 3.0 3.3 1.6 -1.8
Alcohol usually taken with meals 0.3 0.6 0.7 -0.8 -0.7
Nervous feelings 2.5 4.7 7.9 -1.3 2.8
Frequency of tenseness / restlessness in last 2 weeks 2.6 4.0 6.6 -1.2 2.6
Hearing difficulty/problems with background noise 0.3 0.5 0.7 0.9 -0.6
Hair/balding pattern: Pattern 2 4.0 5.1 5.3 2.2 -2.3
Had menopause 0.2 0.3 0.4 -0.7 0.3
Had other major operations 0.4 0.4 0.8 -0.9 0.2
Forced vital capacity (FVC) 1.3 5.1 8.4 -1.4 2.9
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.4 0.5 0.7 0.5
Ever unenthusiastic/disinterested for a whole week 0.1 0.1 0.1 -0.3 -0.2
Qualifications: None of the above 1.9 4.0 5.6 -2.4 1.6
Financial difficulties in last 2 years 1.8 2.4 2.4 1.5 1.6
Mouth/teeth dental problems 0.5 0.8 1.0 0.8 -1.0
Heart attack 6.3 8.1 15.5 0.9 -3.9
Allergy 1.0 2.2 2.3 -1.5 1.5
Pain all over the body in last month 0.8 0.9 1.3 0.7 1.1
Diabetes (self-reported) 0.5 0.8 1.2 -0.6 -1.1
Hayfever/allergic rhinitis (self-reported) 0.2 0.2 0.4 0.7 -0.2
Medication: Ramipril 0.7 0.9 1.0 1.0 -0.8
Medication: Simvastatin 1.7 2.5 4.9 0.1 -2.2
Fluid intelligence score 2.2 4.6 8.1 1.1 -2.8
Illnesses of siblings 1.1 1.6 3.2 0.1 1.8
Neuroticism score 2.9 6.1 6.5 -2.4 2.5
Weight 2.2 11.0 14.7 2.7 -3.8
Impedance of arm (right) 0.7 3.2 5.1 -1.1 2.3
Arm fat percentage (right) 2.0 7.7 10.5 2.2 -3.2
Trunk fat-free mass 1.2 6.7 9.9 1.9 -3.1
Hip circumference 2.5 10.8 11.5 3.2 -3.4
Time employed in main current job 0.1 0.2 0.3 0.1 0.6
Alcohol intake versus 10 years previously 0.9 1.3 2.6 0.3 -1.6
Father’s age at death 0.9 1.2 2.2 0.5 1.5
Worrier / anxious feelings 0.9 1.7 2.7 -0.9 1.6
Frequency of tiredness / lethargy in last 2 weeks 1.3 2.2 2.8 1.2 1.7
Falls in the last year 0.1 0.1 0.2 0.4 -0.3
Hair/balding pattern: Pattern 3 2.0 3.0 3.8 -1.5 2.0
Number of live births 0.4 0.5 0.7 0.8 -0.5
Forced expiratory volume in 1-second (FEV1) 1.7 5.9 10.2 -1.2 3.2
Pulse rate 0.6 1.0 1.3 -0.8 1.1
Happiness 1.3 1.6 2.0 -1.1 1.4
Noisy workplace 0.1 0.2 0.2 0.4 -0.4
Qualifications: A levels/AS levels or equivalent 0.5 1.1 1.5 0.8 -1.2
Serious illness, injury or assault of a close relative in last 2 years 1.7 2.0 3.2 1.8 -0.8
Mouth/teeth dental problems: Dentures 0.6 1.0 2.0 -1.4 -0.2
Asthma 1.2 2.4 4.7 2.2 -0.4
Medication: Ibuprofen (e.g. Nurofen) 3.2 4.0 8.0 0.3 2.8
Medication: Cholesterol lowering 2.5 3.9 7.7 -0.1 -2.8
Depression (self-reported) 3.2 3.9 5.8 -1.4 2.4
Medication: Lansoprazole 0.4 0.5 0.9 1.0 0.2
Prospective memory result 0.5 0.6 1.2 0.0 -1.1
Lung cancer (father) 2.2 2.6 3.2 -1.4 1.8
Illnesses of mother 2.2 2.7 3.2 -1.8 1.5
Forced expiratory volume in 1-second (FEV1), Best measure 1.5 4.7 7.8 -1.3 2.8
Pulse wave Arterial Stiffness index 7.8 9.2 13.2 -3.6 2.3
Impedance of arm (left) 0.4 1.9 3.3 -0.7 1.8
Arm fat mass (right) 2.2 9.2 12.7 2.4 -3.6
Trunk predicted mass 1.1 6.4 9.4 1.9 -3.1
Standing height 0.1 0.6 0.9 1.0 -0.5
Length of working week for main job 1.0 1.1 1.1 1.0 -1.0
Exposure to tobacco smoke at home 0.6 0.6 1.2 -0.2 1.1
Breastfed as a baby 1.9 2.4 4.3 0.7 -2.1
Tense / ‘highly strung’ 2.9 4.8 8.7 -0.9 3.0
Seen doctor (GP) for nerves, anxiety, tension or depression 0.9 1.4 2.1 -1.4 0.8
Hair/balding pattern: Pattern 4 0.2 0.6 1.1 1.0 -0.2
Birth weight of first child 0.5 0.9 1.3 0.7 -1.1
Peak expiratory flow (PEF) 0.0 0.1 0.1 -0.2 -0.3
Pulse wave reflection index 5.2 6.4 8.4 -2.1 2.9
Ever highly irritable/argumentative for 2 days 0.0 0.0 0.0 -0.0 -0.1
Loud music exposure frequency 1.2 1.3 1.4 1.0 -1.2
Qualifications: O levels/GCSEs or equivalent 2.3 3.6 4.7 2.2 -1.6
Mouth/teeth dental problems: Bleeding gums 0.5 0.7 0.8 0.8 -0.9
Blood clot in the leg (DVT) 1.0 1.3 2.3 1.5 -0.6
Medication: Paracetamol 2.7 4.5 4.9 -2.1 2.2
Headache pain in last month 1.8 3.1 3.4 -1.7 1.9
Medication for cholesterol, blood pressure or diabetes 0.8 1.4 2.3 -0.7 1.5
Glaucoma (self-reported) 0.0 0.0 0.1 -0.2 -0.1
Gout (self-reported) 0.3 0.5 0.6 0.6 0.8
Hypothyroidism/myxoedema (self-reported) 0.6 1.2 1.4 1.0 1.2
Medication: Amlodipine 0.1 0.1 0.1 -0.4 0.2
Medication: Ventolin 100micrograms inhaler 0.8 1.0 1.3 1.2 -0.8
Birth weight 0.3 0.7 1.3 1.1 -0.2
Chronic bronchitis/emphysema (mother) 0.3 0.3 0.6 -0.8 -0.1
High blood pressure (siblings) 0.4 0.6 1.1 -1.1 -0.1
Forced vital capacity (FVC), Best measure 1.1 4.2 7.7 -0.8 2.8
Body fat percentage 1.6 6.2 6.8 2.4 -2.6
Leg fat percentage (right) 1.0 3.7 4.0 1.8 -2.0
Arm fat-free mass (right) 1.5 7.6 9.7 2.4 -3.1
Exposure to tobacco smoke outside home 2.8 3.7 7.1 0.5 2.7
Comparative body size at age 10 0.6 1.8 3.1 0.6 -1.8
Number of full brothers 2.1 2.6 2.9 -1.5 -1.7
Worry too long after embarrassment 1.6 2.7 3.9 -1.2 2.0
Seen a psychiatrist for nerves, anxiety, tension or depression 1.0 1.3 2.3 -0.6 1.5
Wheeze or whistling in the chest in last year 0.2 0.4 0.5 0.7 0.6
Number of children fathered 0.1 0.1 0.2 -0.5 -0.2
Reason for reducing amount of alcohol drunk: Health precaution 2.0 2.3 3.2 -1.8 1.2
Age at first live birth 0.5 0.9 1.4 0.6 -1.2
Pulse wave peak to peak time 8.2 9.7 14.1 3.8 -2.3
Health satisfaction 0.2 0.3 0.5 -0.7 -0.2
Shortness of breath walking on level ground 0.3 0.3 0.6 -0.8 -0.2
Qualifications: College or University degree 0.8 2.4 3.3 1.8 -1.2
Eye problems/disorders: None of the above 0.5 0.5 1.1 0.0 1.0
Mouth/teeth dental problems: Loose teeth 0.3 0.3 0.5 -0.4 0.7
Emphysema/chronic bronchitis 1.4 1.5 3.0 -1.7 -0.2
Medication for pain relief, constipation, heartburn 0.3 0.5 0.9 0.1 -0.9
Neck or shoulder pain in last month 3.4 4.8 9.5 -3.1 -0.3
Medication: Blood pressure 0.0 0.1 0.1 -0.2 -0.3
Angina (self-reported) 1.8 2.3 3.0 1.3 -1.7
Migraine (self-reported) 0.6 0.8 1.5 0.2 -1.2
Medication: Ibuprofen 2.9 3.4 6.9 -0.1 2.6
Medication: Allopurinol 0.4 0.6 0.9 0.9 0.5
Medication: Omeprazole 0.7 0.8 1.6 -1.3 0.2
Medication: Seretide 50 evohaler 0.2 0.3 0.5 -0.7 0.0
Mean time to correctly identify matches 0.2 0.3 0.6 0.8 -0.2
Heart disease (mother) 1.8 2.2 2.3 -1.5 -1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.5 0.6 -0.6 -0.8
Whole body fat mass 2.1 8.8 11.4 2.5 -3.4
Leg fat mass (right) 1.6 6.3 7.6 2.2 -2.8
Arm predicted mass (right) 1.6 8.4 9.8 2.6 -3.1
Pulse rate, automated reading 0.9 2.8 3.9 -1.3 2.0
Alcohol intake frequency. 2.0 4.6 5.7 1.9 -2.4
Comparative height size at age 10 0.1 0.5 0.7 0.6 0.8
Number of full sisters 0.1 0.1 0.2 0.3 0.4
Suffer from ‘nerves’ 2.7 4.2 5.6 -2.4 1.7
Overall health rating 0.3 0.7 1.4 1.2 -0.2
Chest pain or discomfort 0.6 0.8 1.7 0.2 1.3
Had major operations 0.6 0.7 1.3 0.2 -1.1
Age at last live birth 0.0 0.1 0.1 0.3 -0.2
Family relationship satisfaction 0.3 0.3 0.6 0.2 -0.8
Leg pain on walking 1.2 1.5 2.9 0.1 -1.7
Qualifications: NVQ or HND or HNC or equivalent 0.7 0.8 1.2 1.1 0.7
Commuting to job workplace: Car/motor vehicle 0.5 0.5 0.6 -0.7 0.8
Illness, injury, bereavement, stress in last 2 years 1.3 1.6 2.7 -1.6 -0.7
Medication: Aspirin 2.4 3.1 4.9 1.1 -2.2
Supplements: Vitamin C 2.5 2.9 5.6 -0.5 2.4
Knee pain experienced in last month 0.6 1.0 1.9 0.2 1.4
Hypertension (Self-reported) 0.0 0.1 0.1 0.2 0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.4 0.6 -0.4 0.8
Illnesses of father: Heart disease 7.1 9.9 17.6 1.5 -4.2
Illnesses of siblings: Diabetes 1.1 1.4 2.7 1.6 -0.0
Smoking status: Previous 0.5 0.8 0.8 -0.9 0.9
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.4 0.4 0.6 0.7
Whole body fat-free mass 1.4 8.3 11.8 2.2 -3.4
Leg fat-free mass (right) 1.7 9.1 13.9 2.1 -3.7
Arm fat percentage (left) 2.1 8.2 10.8 2.4 -3.3
Average weekly red wine intake 0.1 0.2 0.4 -0.6 -0.0
Handedness (chirality/laterality): Left-handed 1.4 1.7 2.5 -1.0 1.6
Mood swings 3.1 5.6 7.5 -1.9 2.7
Loneliness, isolation 0.9 1.2 1.7 -1.3 0.9
Long-standing illness, disability or infirmity 1.9 3.0 3.5 1.6 -1.9
Ever had bowel cancer screening 1.0 1.2 1.8 -1.4 -0.7
Diabetes diagnosed by doctor 2.0 3.2 5.6 -0.9 -2.4
Ever had stillbirth, spontaneous miscarriage or termination 0.2 0.2 0.3 -0.2 0.6
Friendships satisfaction 0.3 0.3 0.6 0.3 -0.8
Qualifications: nursing, teaching 0.2 0.3 0.6 -0.3 -0.8
Commuting to job workplace: Walk 1.2 1.2 2.2 1.5 -0.5
Eye problems/disorders: Cataract 1.5 1.8 3.6 0.0 -1.9
Mouth/teeth dental problems: Mouth ulcers 1.9 3.0 5.1 -0.9 2.2
Medication for cholesterol 0.3 0.5 0.6 -0.8 0.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 3.2 3.8 5.5 -1.5 2.3
Back pain experienced in last month 1.6 2.3 4.6 0.2 2.1
Mineral and other dietary supplements 0.8 1.1 1.7 -0.6 -1.3
Breast cancer (self-reported) 0.7 0.9 1.2 0.8 1.1
Asthma (self-reported) 1.8 3.5 6.8 2.6 -0.5
Osteoporosis (self-reported) 2.3 2.8 4.7 0.9 2.2
Osteoarthritis (self-reported) 0.4 0.5 0.7 0.8 0.6
Medication: Aspirin 2.2 2.8 5.3 0.6 -2.3
Medication: Gliclazide 1.3 1.4 2.1 0.9 -1.4
Illnesses of father: None of the above (group 1) 1.1 1.4 2.8 -0.0 1.7
Smoking status: Current 1.5 2.5 4.1 -0.9 2.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 2.7 5.8 8.0 -1.9 2.8
Whole body water mass 1.5 8.4 12.0 2.2 -3.5
Leg predicted mass (right) 1.7 9.1 13.6 2.1 -3.7
Arm fat mass (left) 2.6 10.6 14.3 2.6 -3.8
Number of self-reported non-cancer illnesses 0.2 0.4 0.7 0.9 0.0
Average weekly champagne plus white wine intake 2.3 3.2 6.2 -0.4 2.5
Miserableness 0.5 0.8 1.3 -1.1 0.5
Guilty feelings 0.1 0.1 0.3 0.0 0.5
Wears glasses or contact lenses 0.8 0.9 1.7 -0.4 -1.3
Ever taken oral contraceptive pill 0.4 0.5 0.9 -0.1 0.9
Hearing aid user 0.3 0.4 0.8 0.9 -0.1
Mother’s age at death 0.5 0.6 0.7 -0.6 -0.8
Financial situation satisfaction 0.5 0.6 0.7 0.8 0.8
Tinnitus: Yes, now most or all of the time 1.6 1.9 2.2 -1.2 1.5
Commuting to job workplace: Public transport 2.3 2.7 4.0 2.0 -1.2
Eye problems/disorders: Glaucoma 0.3 0.3 0.6 -0.2 -0.8
Medication: Blood pressure 0.6 1.2 2.0 0.6 -1.4
Pain type(s) experienced in last month: Hip pain 0.7 0.8 1.3 -0.6 1.1
Supplements: Fish oil (including cod liver oil) 0.4 0.5 0.8 -0.4 0.9
High cholesterol (Self-reported) 4.6 8.2 16.1 0.6 -4.0
Medication: Bendroflumethiazide 0.2 0.4 0.7 0.8 0.2
Medication: Paracetamol 1.6 2.5 3.5 -1.9 1.2
Medication: Lisinopril 0.1 0.1 0.2 -0.2 -0.5
Medication: Atorvastatin 2.6 3.2 5.0 1.2 -2.2
Illnesses of father: High blood pressure 1.0 1.2 1.8 0.8 -1.3
Alcohol drinker status: Never 1.8 2.1 4.3 0.1 -2.1
Ever smoked 2.4 4.3 7.7 -1.0 2.8
Basal metabolic rate 1.7 9.2 13.1 2.3 -3.6
Leg fat percentage (left) 1.4 5.0 6.0 2.0 -2.5
Arm fat-free mass (left) 1.6 8.0 11.2 2.2 -3.3
Number of operations (self-reported) 0.0 0.0 0.1 0.2 0.2
Average weekly beer plus cider intake 1.2 1.8 2.9 -0.8 1.7
Irritability 1.9 3.2 6.4 -0.4 2.5
Risk taking 1.3 1.9 3.4 0.7 1.8
Ever had prostate specific antigen (PSA) test 1.9 2.2 4.4 -2.1 -0.3
Fractured/broken bones in last 5 years 0.8 1.1 1.5 0.8 1.2
Age started oral contraceptive pill 2.2 2.8 5.6 -0.0 -2.4
Diastolic blood pressure, automated reading 0.8 2.5 3.4 -1.8 1.2
Ever depressed for a whole week 3.1 3.9 5.9 -1.4 -2.4
Unable to work because of sickness or disability 0.2 0.2 0.4 -0.2 0.6
Commuting to job workplace: Cycle 0.3 0.4 0.8 -0.9 0.1
Myopia 0.1 0.1 0.2 0.3 -0.4
Vascular/heart problems diagnosed by doctor 0.1 0.3 0.6 -0.1 0.8
Cholesterol lowering medication 3.2 4.7 9.3 0.3 -3.0
Medication: Omeprazole (e.g. Zanprol) 0.4 0.5 0.8 -0.9 0.3
Pain experienced in last month 2.0 3.3 6.2 0.7 -2.5
Supplements: Calcium 2.8 3.1 6.0 0.4 2.4
Basal cell carcinoma (self-reported) 1.0 1.2 2.4 0.0 -1.5
Heart attack/myocardial infarction (self-reported) 5.8 7.5 14.2 0.9 -3.8
Deep venous thrombosis (DVT) (self-reported) 0.5 0.6 1.2 1.1 -0.2
Heart disease (siblings) 6.9 8.5 15.2 1.3 -3.9
Alcohol drinker status: Previous 0.4 0.4 0.8 0.4 0.9
Pack years of smoking 0.1 0.1 0.3 0.5 0.1
Impedance of whole body 1.0 5.3 10.1 -0.8 3.2
Leg fat mass (left) 2.1 8.2 10.2 2.5 -3.2
Arm predicted mass (left) 1.8 9.3 12.6 2.5 -3.5