Hub : Genes

ATXN1L

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Nerve Tibial 0.07 0.034 6.3e-03 0.020 NA 0.008 NA 0.017 1.3e-02 NA 0.08300 NA 2.2e-02
2 YFS Blood 0.02 0.008 9.4e-06 0.017 0.019 0.011 0.018 0.011 2.1e-06 6.5e-07 0.00013 1e-06 9.7e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Alzheimer’s Disease (in mother) 0.3 0.3 0.6 0.2 -0.8
Alzheimer’s Disease (in father) 1.1 1.2 1.8 -1.3 0.8
Alzheimer’s Disease (including proxy) 0.1 0.2 0.3 -0.6 -0.2
Crohns Disease (2017) 0.7 1.5 2.0 1.4 -0.9
Irritable Bowel Disease (IBD) 0.2 0.4 0.4 0.6 -0.7
Ulcerative Colitis (UC) 0.2 0.4 0.8 -0.9 0.2
Major Depression (MDD) 0.5 0.6 1.0 -0.5 1.0
Reaction Time 0.2 0.5 0.7 -0.5 -0.8
Verbal and Numeric Reasoning (VNR) 7.1 17.2 25.9 2.9 -5.1
Breast Cancer 3.9 9.6 15.6 1.9 -4.0
Ovarian Cancer 5.0 6.7 10.6 1.6 -3.3
Prostate Cancer 1.6 2.3 3.6 -1.9 1.0
Age at First Birth 3.4 5.0 6.4 1.9 -2.5
Bipolar Disorder 0.6 0.6 1.2 -0.2 -1.1
Body Mass Index (BMI) (2010) 1.4 1.9 3.8 -0.2 1.9
Coronary Artery Disease (CAD) 1.4 1.7 2.1 1.4 -1.1
Crohns Disease (2012) 0.5 0.9 1.2 -1.1 0.8
Mean Putamen Volume 0.6 0.7 1.3 0.4 -1.1
Fasting Glucose 1.1 1.3 1.6 -1.2 -1.0
HbA1C 0.0 0.0 0.0 -0.1 0.2
HDL Cholesterol 2.9 4.9 6.5 1.8 -2.5
LDL Cholesterol 3.1 4.8 8.7 0.9 -3.0
Lupus 0.1 0.1 0.2 -0.0 -0.4
Neuroticism 0.6 0.8 1.4 1.2 0.6
Primary Biliary Cirrhosis 0.5 0.7 0.9 1.0 -0.7
Rheumatoid Arthritis 3.1 4.3 6.1 -2.5 1.6
Schizophrenia 1.8 4.0 4.3 -1.9 2.1
Triglycerides 0.2 0.3 0.4 0.6 -0.4
Type 2 Diabetes (T2D) 0.6 0.7 0.9 0.7 -1.0
Ulcerative Colitis 0.4 0.6 0.9 1.0 -0.4
Blood Eosinophil Count 0.6 4.8 6.4 -2.5 1.8
Blood Platelet Count 1.1 12.8 19.7 -2.4 4.4
Blood Red Count 0.8 7.6 14.5 -0.9 -3.8
Blood White Count 0.4 3.0 5.4 -2.3 0.8
Heel T-Score 0.9 7.0 13.0 -3.6 1.1
BMI 0.8 4.7 8.7 -0.9 3.0
Height 1.5 30.2 48.7 -3.4 7.0
Waist Hip Ratio (WHR) 0.6 2.6 5.0 -0.4 2.2
Systolic Blood Pressure 5.1 25.7 42.2 3.0 -6.5
Smoking Status 1.3 3.2 5.9 2.4 0.6
Allergy or Eczema 0.1 0.2 0.4 -0.6 -0.2
Cardiovascular Disease 4.0 13.5 19.0 2.8 -4.4
Hypothyroidism (self reported) 0.1 0.1 0.2 -0.3 0.4
Respiratory disease 1.4 3.2 4.9 -1.2 2.2
Type 2 Diabetes (T2D) 0.7 1.3 2.4 -0.4 -1.6
Lung FEV1/FVC ratio 0.5 2.6 4.9 -0.4 2.2
Lung FVC 1.2 6.4 9.0 -3.0 2.0
Neuroticism 2.8 6.8 11.6 -1.4 3.4
Chronotype (morning person) 2.5 5.9 9.0 -3.0 1.7
Hair Pigment 0.4 12.0 13.7 3.2 -3.7
Tanning 1.5 20.8 23.2 -4.8 4.3
Hand grip strength (left) 2.1 5.6 7.9 1.8 -2.8
Number of treatments/medications taken 0.9 1.6 2.4 -1.6 0.8
Average weekly spirits intake 0.2 0.2 0.4 -0.6 0.3
Sensitivity / hurt feelings 0.8 1.4 1.7 1.1 -1.3
Frequency of depressed mood in last 2 weeks 1.9 2.7 3.8 1.3 -1.9
Hearing difficulty/problems: Yes 11.2 17.1 19.3 4.4 -3.9
Relative age of first facial hair 0.3 0.7 1.2 -0.5 -1.1
Other serious medical condition/disability diagnosed by doctor 2.3 3.0 3.5 1.6 -1.9
Ever used hormone-replacement therapy (HRT) 0.4 0.5 0.5 -0.7 -0.6
Ever had hysterectomy (womb removed) 0.7 0.8 1.2 0.7 -1.1
Systolic blood pressure, automated reading 2.6 7.8 13.0 -1.6 3.6
Eye problems/disorders: Diabetes related eye disease 0.2 0.2 0.4 -0.1 0.7
Angina 0.0 0.0 0.1 -0.1 0.3
Medication for hormone replacement therapy 0.5 0.6 1.1 -1.1 -0.0
Vitamin and mineral supplements 1.1 1.5 2.2 0.9 -1.5
Supplements: Zinc 0.2 0.2 0.4 0.6 -0.2
Medication: Co-codamol 1.0 1.2 1.7 0.8 -1.3
Medication: Metformin 0.7 1.0 1.3 1.1 0.9
Diabetes (father) 0.1 0.1 0.1 -0.2 0.3
Diabetes (mother) 2.8 3.5 4.8 2.2 -1.5
Severe depression (siblings) 0.6 0.7 1.4 -1.2 0.1
Pack years adult smoking proportion 0.4 0.7 0.8 -0.9 -0.7
Impedance of leg (right) 0.3 1.4 2.7 -0.3 1.6
Leg fat-free mass (left) 2.1 11.6 17.6 2.4 -4.2
Trunk fat percentage 0.9 3.9 4.4 1.8 -2.1
Hand grip strength (right) 2.0 5.6 9.5 1.3 -3.1
Townsend deprivation index at recruitment 0.8 1.1 1.9 0.6 -1.4
Current tobacco smoking 0.6 1.0 1.7 -1.3 -0.6
Average weekly fortified wine intake 0.6 0.7 1.3 -1.2 0.3
Maternal smoking around birth 0.0 0.1 0.1 0.1 -0.3
Fed-up feelings 4.7 8.7 13.4 2.0 -3.7
Frequency of unenthusiasm / disinterest in last 2 weeks 10.4 13.9 15.1 3.9 -3.6
Relative age voice broke 2.0 3.1 4.5 1.3 -2.1
Taking other prescription medications 1.0 1.5 2.7 1.6 -0.5
Age when periods started (menarche) 0.5 1.1 2.0 0.4 1.4
Bilateral oophorectomy (both ovaries removed) 5.6 6.5 11.4 1.2 -3.4
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.7 1.3 0.4 1.2
Tinnitus: Yes, but not now, but have in the past 0.8 0.8 1.0 -0.8 1.0
Qualifications: CSEs or equivalent 0.5 0.6 0.6 0.8 -0.7
Serious illness, injury or assault to yourself 1.3 1.5 2.1 -1.0 1.5
High blood pressure 3.5 9.9 10.9 -3.0 3.3
Hayfever, allergic rhinitis or eczema 0.2 0.4 0.5 0.6 0.7
Multivitamins +/- minerals 2.1 2.6 3.7 -1.3 1.9
Stomach or abdominal pain in last month 6.7 8.4 10.6 2.5 -3.3
Supplements: Glucosamine 0.3 0.4 0.5 -0.4 0.7
Diverticular disease/diverticulitis (self-reported) 1.7 2.0 3.6 1.9 -0.6
Medication: Atenolol 2.5 3.1 4.7 -1.2 2.2
Medication: Levothyroxine sodium 1.6 2.8 4.3 -2.1 1.1
Sitting height 1.8 13.0 14.8 3.3 -3.9
Chronic bronchitis/emphysema (father) 0.9 1.1 2.1 1.4 -0.3
High blood pressure (mother) 0.9 1.3 1.4 -1.1 1.2
Body mass index (BMI) 1.5 6.4 8.2 2.1 -2.9
Impedance of leg (left) 0.2 1.0 2.0 -0.3 1.4
Leg predicted mass (left) 2.1 11.4 17.4 2.3 -4.2
Trunk fat mass 1.8 8.1 10.4 2.4 -3.2
Waist circumference 2.0 7.4 9.2 2.4 -3.0
Number of incorrect matches in round 0.3 0.5 0.8 -0.9 0.3
Past tobacco smoking 2.5 4.6 8.6 2.9 -0.8
Alcohol usually taken with meals 1.5 2.5 2.6 -1.5 1.6
Nervous feelings 2.2 4.2 5.7 1.6 -2.4
Frequency of tenseness / restlessness in last 2 weeks 2.6 4.1 5.1 1.8 -2.2
Hearing difficulty/problems with background noise 7.1 11.4 11.6 3.4 -3.4
Hair/balding pattern: Pattern 2 0.5 0.6 0.7 0.7 0.9
Had menopause 0.9 1.1 2.0 1.4 -0.5
Had other major operations 2.2 2.7 4.0 2.0 -1.1
Forced vital capacity (FVC) 3.2 12.5 13.6 3.7 -3.4
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.1 1.3 1.1 0.9
Ever unenthusiastic/disinterested for a whole week 0.5 0.7 1.1 -1.1 -0.4
Qualifications: None of the above 9.1 19.7 21.8 4.2 -4.7
Financial difficulties in last 2 years 1.6 2.2 4.2 -2.1 0.4
Mouth/teeth dental problems 1.8 2.8 5.1 -0.7 2.3
Heart attack 1.6 2.0 3.0 -1.0 1.7
Allergy 0.0 0.0 0.1 -0.2 -0.2
Pain all over the body in last month 3.3 3.5 5.4 2.3 -1.3
Diabetes (self-reported) 0.3 0.5 0.9 0.9 0.2
Hayfever/allergic rhinitis (self-reported) 0.1 0.1 0.1 -0.3 0.4
Medication: Ramipril 1.2 1.5 2.0 -1.4 1.0
Medication: Simvastatin 2.8 4.0 7.3 -0.9 2.7
Fluid intelligence score 7.4 15.6 25.4 -2.4 5.0
Illnesses of siblings 0.7 1.1 2.0 -1.4 0.3
Neuroticism score 2.2 4.7 7.7 1.3 -2.8
Weight 2.8 14.0 19.9 2.9 -4.5
Impedance of arm (right) 2.9 13.8 15.3 -3.5 3.9
Arm fat percentage (right) 0.1 0.6 1.0 0.4 -1.0
Trunk fat-free mass 3.6 20.9 30.1 3.4 -5.5
Hip circumference 0.7 2.9 3.2 1.6 -1.8
Time employed in main current job 0.2 0.3 0.3 -0.4 0.6
Alcohol intake versus 10 years previously 2.4 3.7 6.6 2.6 -0.9
Father’s age at death 0.1 0.1 0.2 -0.5 0.2
Worrier / anxious feelings 0.1 0.2 0.5 0.0 0.7
Frequency of tiredness / lethargy in last 2 weeks 8.0 13.1 16.5 4.1 -3.1
Falls in the last year 2.6 3.5 4.6 -2.1 1.5
Hair/balding pattern: Pattern 3 0.3 0.4 0.4 0.7 -0.6
Number of live births 8.1 11.5 12.4 3.3 -3.5
Forced expiratory volume in 1-second (FEV1) 4.1 14.3 14.4 3.8 -3.8
Pulse rate 1.5 2.6 3.2 1.4 -1.8
Happiness 2.1 2.5 4.8 -0.6 -2.2
Noisy workplace 1.1 1.4 2.4 0.6 -1.6
Qualifications: A levels/AS levels or equivalent 2.7 6.0 7.9 -2.0 2.8
Serious illness, injury or assault of a close relative in last 2 years 2.4 2.7 5.3 -0.4 2.3
Mouth/teeth dental problems: Dentures 0.4 0.7 1.2 1.1 -0.4
Asthma 0.1 0.1 0.2 0.5 -0.1
Medication: Ibuprofen (e.g. Nurofen) 0.9 1.1 1.6 -1.3 -0.8
Medication: Cholesterol lowering 6.0 9.2 10.8 -2.8 3.3
Depression (self-reported) 0.5 0.6 0.6 -0.8 0.8
Medication: Lansoprazole 0.4 0.5 0.8 -0.3 0.9
Prospective memory result 4.8 5.9 8.5 1.8 -2.9
Lung cancer (father) 0.2 0.3 0.5 -0.7 -0.3
Illnesses of mother 0.3 0.3 0.6 0.3 -0.8
Forced expiratory volume in 1-second (FEV1), Best measure 4.0 13.1 15.0 3.3 -3.9
Pulse wave Arterial Stiffness index 0.0 0.0 0.1 -0.2 0.2
Impedance of arm (left) 2.0 9.5 11.3 -2.8 3.4
Arm fat mass (right) 1.4 5.8 8.7 1.7 -3.0
Trunk predicted mass 3.6 21.2 30.9 3.4 -5.6
Standing height 1.4 14.2 22.4 2.4 -4.7
Length of working week for main job 5.3 5.9 7.0 -2.7 2.2
Exposure to tobacco smoke at home 0.3 0.3 0.5 0.3 -0.7
Breastfed as a baby 0.5 0.6 1.2 -1.1 -0.3
Tense / ‘highly strung’ 1.9 3.3 5.6 0.9 -2.4
Seen doctor (GP) for nerves, anxiety, tension or depression 0.9 1.4 2.7 -0.1 -1.7
Hair/balding pattern: Pattern 4 0.1 0.2 0.4 -0.0 0.7
Birth weight of first child 0.3 0.5 0.7 -0.6 -0.9
Peak expiratory flow (PEF) 1.2 2.9 4.2 1.3 -2.0
Pulse wave reflection index 1.6 2.0 2.4 -1.6 1.3
Ever highly irritable/argumentative for 2 days 3.3 4.0 6.3 1.3 -2.5
Loud music exposure frequency 4.7 5.1 9.8 0.6 -3.1
Qualifications: O levels/GCSEs or equivalent 5.4 8.7 13.8 -1.9 3.7
Mouth/teeth dental problems: Bleeding gums 0.3 0.4 0.5 -0.6 -0.7
Blood clot in the leg (DVT) 0.1 0.2 0.2 -0.3 -0.5
Medication: Paracetamol 1.7 2.9 4.1 1.3 -2.0
Headache pain in last month 0.8 1.5 2.8 0.4 -1.7
Medication for cholesterol, blood pressure or diabetes 2.7 4.5 6.2 1.7 -2.5
Glaucoma (self-reported) 0.0 0.0 0.1 0.1 -0.2
Gout (self-reported) 0.3 0.4 0.6 -0.8 0.5
Hypothyroidism/myxoedema (self-reported) 0.2 0.5 0.7 -0.8 0.5
Medication: Amlodipine 0.0 0.0 0.1 -0.3 0.0
Medication: Ventolin 100micrograms inhaler 0.3 0.3 0.5 0.7 -0.4
Birth weight 1.8 3.9 6.4 -2.5 1.2
Chronic bronchitis/emphysema (mother) 0.4 0.5 0.8 0.9 -0.5
High blood pressure (siblings) 0.1 0.2 0.2 -0.4 0.4
Forced vital capacity (FVC), Best measure 4.3 16.1 16.2 4.0 -4.0
Body fat percentage 0.8 3.1 3.5 1.7 -1.9
Leg fat percentage (right) 0.7 2.7 3.1 1.5 -1.8
Arm fat-free mass (right) 5.1 26.7 35.3 4.3 -5.9
Exposure to tobacco smoke outside home 0.1 0.1 0.2 -0.4 -0.1
Comparative body size at age 10 0.1 0.3 0.6 0.8 -0.1
Number of full brothers 0.1 0.1 0.2 0.4 -0.2
Worry too long after embarrassment 0.7 1.1 1.3 1.2 -1.0
Seen a psychiatrist for nerves, anxiety, tension or depression 2.5 3.2 5.0 1.2 -2.2
Wheeze or whistling in the chest in last year 0.5 0.9 1.3 1.1 -0.7
Number of children fathered 2.5 2.8 3.1 1.7 -1.6
Reason for reducing amount of alcohol drunk: Health precaution 0.3 0.4 0.7 0.8 0.3
Age at first live birth 5.4 9.7 12.1 -2.7 3.5
Pulse wave peak to peak time 0.2 0.2 0.2 0.5 -0.4
Health satisfaction 3.6 4.6 6.2 1.7 -2.5
Shortness of breath walking on level ground 4.9 5.8 7.9 1.9 -2.8
Qualifications: College or University degree 6.8 21.6 25.9 -5.1 4.2
Eye problems/disorders: None of the above 0.2 0.2 0.4 0.6 -0.3
Mouth/teeth dental problems: Loose teeth 0.3 0.4 0.6 -0.7 -0.5
Emphysema/chronic bronchitis 4.6 5.2 5.7 2.2 -2.4
Medication for pain relief, constipation, heartburn 0.8 1.4 1.9 0.9 1.4
Neck or shoulder pain in last month 18.0 25.6 31.5 4.4 -5.6
Medication: Blood pressure 0.8 1.5 2.0 -1.0 1.4
Angina (self-reported) 0.0 0.0 0.0 0.0 0.2
Migraine (self-reported) 0.8 1.0 1.8 -1.3 0.4
Medication: Ibuprofen 1.0 1.2 2.2 -1.5 -0.5
Medication: Allopurinol 0.4 0.5 1.0 -1.0 0.2
Medication: Omeprazole 0.2 0.2 0.4 -0.3 -0.6
Medication: Seretide 50 evohaler 0.3 0.3 0.4 0.5 -0.7
Mean time to correctly identify matches 0.1 0.2 0.4 0.2 0.6
Heart disease (mother) 0.1 0.1 0.1 0.3 0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.8 1.0 1.2 0.9 -1.1
Whole body fat mass 1.9 8.1 10.4 2.4 -3.2
Leg fat mass (right) 1.8 7.0 8.8 2.3 -3.0
Arm predicted mass (right) 4.9 25.7 33.4 4.2 -5.8
Pulse rate, automated reading 1.9 6.2 6.4 2.5 -2.5
Alcohol intake frequency. 3.3 7.9 11.2 3.3 -2.2
Comparative height size at age 10 3.6 20.0 31.6 2.9 -5.6
Number of full sisters 1.2 1.4 2.3 1.5 -0.7
Suffer from ‘nerves’ 0.4 0.7 1.3 -0.1 -1.1
Overall health rating 12.2 26.3 27.7 5.0 -5.3
Chest pain or discomfort 0.2 0.2 0.4 0.7 -0.1
Had major operations 0.2 0.2 0.3 -0.4 0.6
Age at last live birth 2.5 3.7 4.4 -2.1 1.7
Family relationship satisfaction 3.0 3.7 5.2 1.5 -2.3
Leg pain on walking 1.7 2.1 2.3 1.4 -1.5
Qualifications: NVQ or HND or HNC or equivalent 0.1 0.1 0.2 0.4 -0.2
Commuting to job workplace: Car/motor vehicle 6.8 7.8 10.7 2.2 -3.3
Illness, injury, bereavement, stress in last 2 years 0.4 0.5 0.9 1.0 -0.1
Medication: Aspirin 3.7 4.9 6.2 -2.5 1.9
Supplements: Vitamin C 0.0 0.0 0.0 -0.0 -0.2
Knee pain experienced in last month 6.5 10.1 11.1 3.3 -3.0
Hypertension (Self-reported) 3.0 8.4 9.0 -2.8 3.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.1 0.2 0.2 -0.5 -0.3
Illnesses of father: Heart disease 0.7 1.0 1.7 -0.6 -1.3
Illnesses of siblings: Diabetes 0.1 0.1 0.2 0.4 -0.1
Smoking status: Previous 1.5 2.3 3.9 -2.0 0.8
Forced expiratory volume in 1-second (FEV1), predicted 0.5 1.0 1.9 0.4 -1.4
Whole body fat-free mass 3.3 19.1 27.5 3.3 -5.2
Leg fat-free mass (right) 2.2 11.8 18.3 2.3 -4.3
Arm fat percentage (left) 0.3 1.1 1.7 0.8 -1.3
Average weekly red wine intake 2.0 2.9 3.1 -1.8 1.7
Handedness (chirality/laterality): Left-handed 0.0 0.0 0.1 -0.1 -0.2
Mood swings 2.2 4.0 6.4 1.2 -2.5
Loneliness, isolation 1.1 1.5 2.0 1.0 -1.4
Long-standing illness, disability or infirmity 0.5 0.8 0.9 0.8 -0.9
Ever had bowel cancer screening 3.2 3.8 4.7 2.2 -1.7
Diabetes diagnosed by doctor 0.4 0.7 1.3 0.4 1.1
Ever had stillbirth, spontaneous miscarriage or termination 0.2 0.2 0.4 -0.2 0.6
Friendships satisfaction 0.8 0.9 1.8 -0.1 -1.4
Qualifications: nursing, teaching 3.9 6.1 7.0 -2.3 2.7
Commuting to job workplace: Walk 2.8 3.0 5.8 -0.6 2.4
Eye problems/disorders: Cataract 1.4 1.6 2.0 -1.1 1.4
Mouth/teeth dental problems: Mouth ulcers 0.5 0.7 1.5 0.0 -1.2
Medication for cholesterol 2.3 3.5 3.6 1.8 -1.9
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.4 0.5 1.0 1.0 0.1
Back pain experienced in last month 11.5 16.9 17.8 4.2 -4.0
Mineral and other dietary supplements 0.8 1.0 2.0 0.3 -1.4
Breast cancer (self-reported) 4.2 5.0 6.1 2.0 -2.5
Asthma (self-reported) 0.1 0.2 0.4 0.6 -0.2
Osteoporosis (self-reported) 2.2 2.7 3.9 -2.0 1.2
Osteoarthritis (self-reported) 0.3 0.4 0.9 0.9 -0.0
Medication: Aspirin 2.7 3.5 4.1 -2.0 1.7
Medication: Gliclazide 0.9 1.1 1.4 1.2 -0.8
Illnesses of father: None of the above (group 1) 0.4 0.5 0.9 -1.0 0.3
Smoking status: Current 0.7 1.2 1.9 -1.4 -0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage 4.4 9.4 11.6 3.4 -2.7
Whole body water mass 3.3 19.1 27.7 3.2 -5.3
Leg predicted mass (right) 2.2 11.8 18.3 2.3 -4.3
Arm fat mass (left) 1.8 7.4 10.3 2.1 -3.2
Number of self-reported non-cancer illnesses 0.8 1.4 1.5 -1.1 1.2
Average weekly champagne plus white wine intake 0.0 0.0 0.1 0.0 0.3
Miserableness 0.3 0.6 0.7 -0.8 -0.7
Guilty feelings 1.2 1.9 2.0 1.3 -1.4
Wears glasses or contact lenses 2.6 3.0 3.2 -1.7 1.8
Ever taken oral contraceptive pill 1.0 1.1 2.1 -1.5 0.3
Hearing aid user 0.1 0.1 0.1 0.4 -0.1
Mother’s age at death 0.5 0.7 1.3 1.2 -0.1
Financial situation satisfaction 1.0 1.2 1.4 -1.2 -1.0
Tinnitus: Yes, now most or all of the time 0.1 0.1 0.2 -0.1 -0.5
Commuting to job workplace: Public transport 6.5 7.8 10.0 -2.3 3.2
Eye problems/disorders: Glaucoma 0.2 0.2 0.3 0.5 0.5
Medication: Blood pressure 4.0 7.6 8.0 -2.8 2.7
Pain type(s) experienced in last month: Hip pain 4.3 5.4 5.5 2.3 -2.3
Supplements: Fish oil (including cod liver oil) 0.2 0.3 0.6 -0.2 0.8
High cholesterol (Self-reported) 2.9 5.1 9.8 -0.6 3.1
Medication: Bendroflumethiazide 4.9 7.4 9.4 -3.1 2.3
Medication: Paracetamol 1.2 1.8 2.4 1.2 -1.5
Medication: Lisinopril 2.4 3.2 3.9 -1.6 2.0
Medication: Atorvastatin 6.9 8.5 10.4 -2.6 3.2
Illnesses of father: High blood pressure 3.0 3.7 4.3 -1.8 2.1
Alcohol drinker status: Never 0.7 0.8 1.6 -0.2 1.3
Ever smoked 1.5 2.7 5.4 -2.3 0.1
Basal metabolic rate 3.3 18.4 26.5 3.2 -5.2
Leg fat percentage (left) 1.0 3.6 4.3 1.7 -2.1
Arm fat-free mass (left) 4.7 24.1 32.5 4.0 -5.7
Number of operations (self-reported) 1.3 2.0 3.2 0.9 -1.8
Average weekly beer plus cider intake 1.2 1.8 2.6 1.0 -1.6
Irritability 2.8 4.8 7.1 1.5 -2.7
Risk taking 1.0 1.4 2.2 -1.5 -0.8
Ever had prostate specific antigen (PSA) test 0.9 1.0 1.9 1.4 -0.0
Fractured/broken bones in last 5 years 0.4 0.6 1.1 -1.1 0.0
Age started oral contraceptive pill 1.5 1.9 2.5 -1.2 1.6
Diastolic blood pressure, automated reading 3.2 9.9 12.1 -3.5 2.8
Ever depressed for a whole week 0.7 0.9 0.9 -1.0 -0.9
Unable to work because of sickness or disability 1.3 1.7 2.4 1.6 -0.9
Commuting to job workplace: Cycle 0.9 1.1 1.2 -1.1 1.0
Myopia 0.1 0.2 0.3 0.6 -0.3
Vascular/heart problems diagnosed by doctor 3.4 9.5 11.0 2.8 -3.3
Cholesterol lowering medication 1.6 2.4 4.5 0.4 2.1
Medication: Omeprazole (e.g. Zanprol) 0.0 0.0 0.0 -0.1 -0.2
Pain experienced in last month 16.8 28.4 33.1 -4.9 5.8
Supplements: Calcium 2.0 2.3 2.8 -1.7 1.3
Basal cell carcinoma (self-reported) 0.5 0.6 0.6 0.8 0.8
Heart attack/myocardial infarction (self-reported) 1.4 1.8 2.5 -1.0 1.6
Deep venous thrombosis (DVT) (self-reported) 0.4 0.5 1.0 0.0 -1.0
Heart disease (siblings) 2.5 3.1 5.2 2.3 -1.0
Alcohol drinker status: Previous 0.5 0.6 1.0 0.3 -1.0
Pack years of smoking 0.5 0.7 1.4 -1.2 -0.2
Impedance of whole body 0.7 3.8 5.6 -1.4 2.4
Leg fat mass (left) 2.0 8.2 10.4 2.4 -3.2
Arm predicted mass (left) 4.5 23.3 30.8 4.0 -5.5