Hub : Genes

C1orf87

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 NTR Blood 0.0151 0.0075 0.0081 -0.001 0.002 -0.001 0.002 -0.001 0.840 0.0830 0.8700 0.076 0.830
2 TCGA Kidney Renal Papillary Cell Carcinoma 0.0780 0.0390 0.0056 0.025 0.030 0.043 NA 0.032 0.014 0.0079 0.0016 NA 0.006

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 2.4 3.7 5.1 -2.3 -1.5
Bipolar Disorder or Schizophrenia 1.9 4.5 7.0 -2.6 -1.4
Depressed Affect (Nagel 2018) 0.2 0.5 0.9 -1.0 -0.2
Depression (Nagel 2018) 0.5 0.8 1.3 1.1 -0.5
Intelligence (Savage-Jansen 2018) 0.0 0.1 0.2 0.1 -0.5
Neuroticism (Nagel 2018) 0.0 0.1 0.1 -0.0 0.3
Schizophrenia (2018) 0.7 1.4 2.5 -1.6 -0.6
Schizophrenia vs Biploar Disorder 0.7 1.0 1.8 -0.4 -1.3
Worry (Nagel 2018) 0.0 0.1 0.1 0.3 0.3
Alzheimer’s Disease (in mother) 0.4 0.5 0.5 -0.7 0.6
Alzheimer’s Disease (in father) 1.6 1.7 3.1 1.8 0.6
Alzheimer’s Disease (including proxy) 0.8 1.2 2.4 0.2 1.6
Crohns Disease (2017) 0.6 1.4 2.4 0.6 -1.6
Irritable Bowel Disease (IBD) 1.0 2.3 4.5 0.2 -2.1
Ulcerative Colitis (UC) 0.9 1.7 2.8 -0.7 -1.7
Major Depression (MDD) 1.2 1.4 2.1 -1.4 -0.9
Reaction Time 1.1 2.2 3.9 -2.0 -0.7
Verbal and Numeric Reasoning (VNR) 0.0 0.0 0.1 -0.0 -0.3
Breast Cancer 2.2 5.2 6.7 -1.9 2.6
Ovarian Cancer 1.8 2.4 4.7 2.2 -0.1
Prostate Cancer 2.3 3.2 6.2 2.5 -0.3
Age at First Birth 3.3 4.9 6.6 1.8 2.6
Bipolar Disorder (2011) 0.9 0.9 1.7 -0.2 1.3
Body Mass Index (BMI) (2010) 0.0 0.0 0.1 -0.1 0.2
Coronary Artery Disease (CAD) 0.4 0.4 0.8 0.9 0.3
Crohns Disease (2012) 0.5 0.9 1.6 1.3 -0.4
Mean Putamen Volume 0.2 0.2 0.4 0.3 0.6
Fasting Glucose 0.5 0.6 1.0 -0.4 1.0
HbA1C 0.2 0.2 0.3 -0.4 0.5
HDL Cholesterol 0.3 0.5 0.5 -0.7 0.7
LDL Cholesterol 3.1 4.9 8.0 1.3 2.8
Lupus 0.9 1.3 2.5 1.6 0.3
Neuroticism (2016) 0.4 0.5 0.9 -0.9 -0.5
Primary Biliary Cirrhosis 0.4 0.5 0.8 -0.9 -0.5
Rheumatoid Arthritis 0.1 0.2 0.4 -0.6 0.2
Schizophrenia (2014) 1.1 2.4 3.6 -1.9 -1.1
Triglycerides 0.0 0.1 0.1 0.2 -0.3
Type 2 Diabetes (T2D) (2012) 0.4 0.5 0.7 0.8 0.5
Ulcerative Colitis 1.2 1.7 3.0 -0.6 -1.7
Blood Eosinophil Count 0.1 0.8 1.5 1.2 0.4
Blood Platelet Count 0.2 1.8 3.5 -0.2 1.9
Blood Red Count 1.7 16.1 26.0 -5.1 -2.5
Blood White Count 0.1 0.4 0.8 0.3 -0.9
Heel T-Score 0.0 0.2 0.3 0.3 -0.6
BMI 0.5 2.8 5.6 -0.2 -2.4
Height 0.2 3.5 7.0 0.2 2.6
Waist Hip Ratio (WHR) 0.2 0.9 1.7 1.3 -0.2
Systolic Blood Pressure 0.6 3.1 3.9 -1.5 -2.0
Smoking Status 0.7 1.8 3.5 -1.9 -0.2
Allergy or Eczema 1.4 3.7 6.2 1.2 2.5
Cardiovascular Disease 0.2 0.7 1.4 1.2 -0.1
Hypothyroidism (self reported) 0.4 0.8 1.7 -1.3 0.1
Respiratory disease 0.1 0.3 0.5 -0.1 0.7
Type 2 Diabetes (T2D) (2018) 0.9 1.8 2.0 -1.4 -1.3
Lung FEV1/FVC ratio 0.2 1.0 1.5 0.8 -1.2
Lung FVC 0.5 2.6 3.5 -1.9 1.3
Neuroticism 0.1 0.3 0.5 -0.7 0.0
Chronotype (morning person) 0.1 0.2 0.3 -0.5 -0.3
Hair Pigment 0.0 0.9 1.7 -1.3 0.1
Tanning 0.0 0.6 1.1 1.1 0.0
Hand grip strength (left) 0.2 0.4 0.8 -0.9 0.2
Number of treatments/medications taken 0.7 1.3 2.6 -0.0 1.6
Average weekly spirits intake 0.9 1.2 2.2 1.5 0.3
Sensitivity / hurt feelings 0.2 0.4 0.7 0.8 -0.3
Frequency of depressed mood in last 2 weeks 0.5 0.8 1.3 0.4 -1.2
Hearing difficulty/problems: Yes 0.7 1.0 2.0 1.4 -0.0
Relative age of first facial hair 0.1 0.2 0.3 0.6 -0.2
Other serious medical condition/disability diagnosed by doctor 0.7 0.9 1.6 -1.3 -0.4
Ever used hormone-replacement therapy (HRT) 0.3 0.4 0.9 -0.0 0.9
Ever had hysterectomy (womb removed) 0.1 0.2 0.2 -0.3 0.5
Systolic blood pressure, automated reading 0.6 1.9 2.0 -1.3 -1.4
Eye problems/disorders: Diabetes related eye disease 2.3 2.5 3.7 -1.1 -1.9
Angina 2.6 3.4 6.2 -0.8 -2.5
Medication for hormone replacement therapy 0.8 0.9 1.0 -0.9 -1.0
Vitamin and mineral supplements 1.8 2.5 4.8 2.2 0.4
Supplements: Zinc 1.1 1.2 2.3 -1.5 0.3
Medication: Co-codamol 1.3 1.5 3.0 1.7 0.4
Medication: Metformin 0.8 1.1 2.1 0.1 -1.5
Diabetes (father) 0.9 1.1 2.1 1.5 0.4
Diabetes (mother) 1.6 2.0 3.8 -2.0 -0.5
Severe depression (siblings) 3.7 4.1 5.2 -2.3 -1.7
Pack years adult smoking proportion 4.4 6.7 9.6 -3.1 -1.9
Impedance of leg (right) 0.4 1.8 3.6 0.2 1.9
Leg fat-free mass (left) 0.2 1.2 1.9 -0.7 -1.4
Trunk fat percentage 0.5 2.0 3.4 0.8 -1.9
Hand grip strength (right) 0.2 0.5 0.9 -1.0 0.1
Townsend deprivation index at recruitment 2.0 2.8 4.8 -2.2 -0.9
Current tobacco smoking 0.2 0.3 0.4 -0.6 -0.5
Average weekly fortified wine intake 0.5 0.6 1.1 1.0 -0.2
Maternal smoking around birth 2.1 3.0 6.0 -0.3 -2.5
Fed-up feelings 0.2 0.5 0.8 -0.9 -0.3
Frequency of unenthusiasm / disinterest in last 2 weeks 1.2 1.6 2.9 0.5 -1.7
Relative age voice broke 0.5 0.8 1.3 -0.5 1.1
Taking other prescription medications 0.2 0.3 0.6 0.8 -0.0
Age when periods started (menarche) 0.8 1.8 3.6 0.3 1.9
Bilateral oophorectomy (both ovaries removed) 1.9 2.1 3.5 -0.9 1.9
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.0 2.0 1.4 -0.1
Tinnitus: Yes, but not now, but have in the past 0.3 0.3 0.3 -0.5 0.6
Qualifications: CSEs or equivalent 0.1 0.2 0.3 0.6 0.1
Serious illness, injury or assault to yourself 0.8 1.0 1.9 1.4 0.3
High blood pressure 0.1 0.2 0.3 -0.3 -0.6
Hayfever, allergic rhinitis or eczema 0.6 1.4 2.8 0.2 1.7
Multivitamins +/- minerals 0.6 0.7 1.0 -1.0 -0.6
Stomach or abdominal pain in last month 0.9 1.1 2.2 1.5 0.0
Supplements: Glucosamine 0.1 0.2 0.3 -0.5 -0.1
Diverticular disease/diverticulitis (self-reported) 0.5 0.6 0.8 -0.6 0.9
Medication: Atenolol 0.7 0.9 1.8 1.3 0.2
Medication: Levothyroxine sodium 0.2 0.3 0.6 -0.3 0.8
Sitting height 0.1 0.6 0.7 -0.8 0.7
Chronic bronchitis/emphysema (father) 0.2 0.3 0.5 -0.7 -0.3
High blood pressure (mother) 0.6 0.8 1.4 -1.2 -0.4
Body mass index (BMI) 1.5 6.5 12.2 0.9 -3.5
Impedance of leg (left) 0.5 2.6 4.4 0.9 2.1
Leg predicted mass (left) 0.2 1.2 2.0 -0.6 -1.4
Trunk fat mass 0.6 2.7 4.7 0.8 -2.2
Waist circumference 1.0 3.7 6.4 1.0 -2.5
Number of incorrect matches in round 0.2 0.2 0.5 0.7 0.0
Past tobacco smoking 0.5 0.9 1.7 1.3 0.3
Alcohol usually taken with meals 0.1 0.1 0.2 -0.5 0.2
Nervous feelings 0.5 0.9 1.0 0.9 1.0
Frequency of tenseness / restlessness in last 2 weeks 0.2 0.2 0.5 0.1 0.7
Hearing difficulty/problems with background noise 0.7 1.1 2.1 1.4 -0.3
Hair/balding pattern: Pattern 2 1.7 2.2 4.3 -2.1 0.2
Had menopause 1.6 2.0 4.0 0.0 2.0
Had other major operations 1.1 1.3 2.0 -0.8 -1.4
Forced vital capacity (FVC) 0.9 3.6 7.1 -2.7 0.4
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.6 1.1 1.1 -0.0
Ever unenthusiastic/disinterested for a whole week 1.7 2.0 3.6 -0.7 -1.9
Qualifications: None of the above 2.3 4.8 7.1 -2.7 -1.6
Financial difficulties in last 2 years 0.4 0.5 1.0 1.0 0.3
Mouth/teeth dental problems 0.2 0.3 0.5 0.7 0.5
Heart attack 0.3 0.3 0.6 0.8 -0.3
Allergy 0.3 0.6 0.7 -0.7 -0.9
Pain all over the body in last month 0.2 0.3 0.4 0.6 0.4
Diabetes (self-reported) 0.8 1.2 2.0 -0.6 -1.4
Hayfever/allergic rhinitis (self-reported) 1.3 1.7 2.3 1.1 1.5
Medication: Ramipril 0.2 0.3 0.5 0.7 0.3
Medication: Simvastatin 1.3 2.0 3.8 0.4 1.9
Fluid intelligence score 0.5 1.1 2.1 0.3 1.5
Illnesses of siblings 1.2 1.7 2.1 1.4 1.2
Neuroticism score 0.5 1.1 1.6 -1.3 -0.8
Weight 0.7 3.5 6.7 0.5 -2.6
Impedance of arm (right) 0.8 3.7 7.2 -0.4 2.7
Arm fat percentage (right) 1.1 4.3 7.7 0.9 -2.8
Trunk fat-free mass 0.1 0.8 1.5 -0.1 -1.2
Hip circumference 0.7 3.0 5.7 0.6 -2.4
Time employed in main current job 0.9 1.0 2.1 1.4 -0.1
Alcohol intake versus 10 years previously 0.8 1.3 2.3 -1.5 -0.5
Father’s age at death 1.7 2.2 2.7 1.3 1.6
Worrier / anxious feelings 0.4 0.7 1.4 0.1 -1.2
Frequency of tiredness / lethargy in last 2 weeks 0.6 1.0 2.0 -0.2 -1.4
Falls in the last year 0.3 0.5 0.8 0.3 -0.9
Hair/balding pattern: Pattern 3 1.1 1.6 2.1 1.5 1.1
Number of live births 1.4 2.0 3.5 -1.9 -0.8
Forced expiratory volume in 1-second (FEV1) 0.6 2.0 3.8 -2.0 0.3
Pulse rate 0.4 0.7 0.9 -0.9 -0.7
Happiness 0.5 0.6 1.0 -0.4 1.0
Noisy workplace 0.1 0.1 0.1 0.3 -0.3
Qualifications: A levels/AS levels or equivalent 2.8 6.2 9.3 3.0 1.8
Serious illness, injury or assault of a close relative in last 2 years 0.1 0.1 0.2 -0.4 -0.3
Mouth/teeth dental problems: Dentures 1.7 2.8 3.5 1.9 1.5
Asthma 0.3 0.5 0.6 0.6 0.8
Medication: Ibuprofen (e.g. Nurofen) 3.3 4.2 7.1 1.2 2.7
Medication: Cholesterol lowering 0.4 0.6 1.1 0.2 -1.1
Depression (self-reported) 0.4 0.4 0.8 -0.2 0.9
Medication: Lansoprazole 1.3 1.5 2.6 -0.7 -1.6
Prospective memory result 0.2 0.3 0.4 0.7 -0.3
Lung cancer (father) 4.4 5.2 9.1 1.1 -3.0
Illnesses of mother 0.1 0.1 0.1 0.3 -0.1
Forced expiratory volume in 1-second (FEV1), Best measure 0.5 1.5 2.7 -1.6 0.6
Pulse wave Arterial Stiffness index 4.0 4.6 6.9 -2.6 -1.5
Impedance of arm (left) 0.6 2.9 4.7 -1.1 2.2
Arm fat mass (right) 0.9 3.8 7.2 0.5 -2.7
Trunk predicted mass 0.1 0.8 1.6 -0.2 -1.3
Standing height 0.2 1.8 2.5 -1.0 1.6
Length of working week for main job 1.8 2.0 3.9 -2.0 0.2
Exposure to tobacco smoke at home 0.9 1.0 1.8 -0.5 -1.3
Breastfed as a baby 0.2 0.2 0.3 0.2 0.6
Tense / ‘highly strung’ 0.1 0.1 0.2 0.3 0.4
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.4 0.4 0.6 -0.6
Hair/balding pattern: Pattern 4 1.1 2.7 5.5 2.3 0.1
Birth weight of first child 0.7 1.2 1.5 1.2 1.0
Peak expiratory flow (PEF) 0.4 1.0 2.1 -0.0 1.4
Pulse wave reflection index 0.9 1.1 2.0 -0.5 1.4
Ever highly irritable/argumentative for 2 days 0.4 0.4 0.6 -0.8 0.5
Loud music exposure frequency 1.6 1.8 3.1 -1.8 -0.7
Qualifications: O levels/GCSEs or equivalent 1.5 2.4 2.9 1.4 1.7
Mouth/teeth dental problems: Bleeding gums 4.8 6.2 6.5 -2.6 -2.4
Blood clot in the leg (DVT) 2.0 2.5 4.7 0.6 -2.2
Medication: Paracetamol 2.6 4.4 6.9 1.4 2.6
Headache pain in last month 1.1 1.9 1.9 1.3 1.4
Medication for cholesterol, blood pressure or diabetes 0.1 0.2 0.2 -0.4 -0.4
Glaucoma (self-reported) 2.1 2.5 4.8 -0.5 -2.2
Gout (self-reported) 2.6 3.6 7.2 0.1 -2.7
Hypothyroidism/myxoedema (self-reported) 0.5 0.9 1.8 -1.3 -0.2
Medication: Amlodipine 0.7 1.0 1.2 0.9 -1.1
Medication: Ventolin 100micrograms inhaler 1.1 1.4 2.6 1.6 -0.4
Birth weight 0.2 0.4 0.8 -0.9 -0.0
Chronic bronchitis/emphysema (mother) 0.1 0.1 0.3 0.5 0.0
High blood pressure (siblings) 0.4 0.6 0.6 -0.7 -0.8
Forced vital capacity (FVC), Best measure 0.6 2.3 3.7 -1.9 0.9
Body fat percentage 0.8 3.2 5.3 1.1 -2.3
Leg fat percentage (right) 1.1 3.9 6.3 1.3 -2.5
Arm fat-free mass (right) 0.2 1.1 2.2 -0.3 -1.5
Exposure to tobacco smoke outside home 7.7 10.3 13.3 -3.6 -2.7
Comparative body size at age 10 1.7 4.7 8.6 2.9 -0.8
Number of full brothers 2.3 2.9 4.5 -1.1 -2.1
Worry too long after embarrassment 0.0 0.0 0.1 0.2 -0.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.6 0.7 0.8 -0.8 0.9
Wheeze or whistling in the chest in last year 0.3 0.6 1.1 1.1 0.1
Number of children fathered 2.2 2.5 3.6 1.9 1.2
Reason for reducing amount of alcohol drunk: Health precaution 1.5 1.7 3.3 -1.8 -0.2
Age at first live birth 1.3 2.4 3.3 1.8 1.2
Pulse wave peak to peak time 3.4 4.0 5.7 2.4 1.5
Health satisfaction 2.6 3.3 4.0 -2.0 -1.6
Shortness of breath walking on level ground 0.6 0.7 1.3 -1.1 0.3
Qualifications: College or University degree 0.1 0.2 0.3 0.5 0.3
Eye problems/disorders: None of the above 0.4 0.5 0.6 -0.6 0.8
Mouth/teeth dental problems: Loose teeth 1.7 2.0 3.4 -1.9 -0.7
Emphysema/chronic bronchitis 0.4 0.5 0.7 -0.8 -0.6
Medication for pain relief, constipation, heartburn 0.7 1.2 1.7 -0.8 -1.3
Neck or shoulder pain in last month 2.4 3.4 3.5 1.8 -1.9
Medication: Blood pressure 0.1 0.3 0.3 0.4 0.6
Angina (self-reported) 2.9 3.8 7.0 -0.8 -2.6
Migraine (self-reported) 4.1 5.0 6.9 2.6 1.8
Medication: Ibuprofen 2.9 3.4 6.1 0.9 2.5
Medication: Allopurinol 1.3 1.7 3.4 0.1 -1.8
Medication: Omeprazole 1.3 1.5 2.5 0.7 -1.6
Medication: Seretide 50 evohaler 1.0 1.2 1.6 -1.3 -0.9
Mean time to correctly identify matches 0.4 0.7 1.3 -1.1 -0.5
Heart disease (mother) 0.0 0.0 0.1 -0.2 0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.9 1.1 1.3 1.1 1.0
Whole body fat mass 0.9 3.8 7.1 0.7 -2.7
Leg fat mass (right) 0.9 3.4 6.2 0.8 -2.5
Arm predicted mass (right) 0.1 0.6 1.2 -0.2 -1.1
Pulse rate, automated reading 0.2 0.5 1.1 -1.0 0.1
Alcohol intake frequency. 0.5 1.2 1.8 -0.7 -1.4
Comparative height size at age 10 0.0 0.1 0.1 0.2 -0.3
Number of full sisters 2.3 2.8 3.6 -1.9 -1.4
Suffer from ‘nerves’ 1.1 1.7 2.2 -1.5 1.1
Overall health rating 0.6 1.3 1.5 -1.1 -1.2
Chest pain or discomfort 2.7 3.9 4.4 -2.1 -1.8
Had major operations 0.1 0.1 0.3 -0.1 -0.5
Age at last live birth 0.1 0.2 0.2 0.4 0.4
Family relationship satisfaction 2.6 3.2 4.2 -1.4 2.1
Leg pain on walking 0.5 0.6 0.6 -0.8 -0.8
Qualifications: NVQ or HND or HNC or equivalent 1.1 1.3 2.0 1.4 0.7
Commuting to job workplace: Car/motor vehicle 1.1 1.3 2.2 1.5 -0.5
Illness, injury, bereavement, stress in last 2 years 0.3 0.4 0.8 -0.2 -0.9
Medication: Aspirin 0.3 0.4 0.6 -0.8 -0.5
Supplements: Vitamin C 1.9 2.2 4.4 -2.1 0.1
Knee pain experienced in last month 0.3 0.5 1.0 -0.1 1.0
Hypertension (Self-reported) 0.1 0.4 0.7 -0.3 -0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 2.7 3.1 4.6 -2.1 -1.3
Illnesses of father: Heart disease 0.0 0.0 0.1 -0.2 -0.1
Illnesses of siblings: Diabetes 1.6 2.0 4.0 0.1 -2.0
Smoking status: Previous 0.6 0.9 1.6 -1.3 -0.4
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.7 1.3 0.3 1.2
Whole body fat-free mass 0.1 0.8 1.6 -0.3 -1.3
Leg fat-free mass (right) 0.1 0.7 1.3 -0.4 -1.1
Arm fat percentage (left) 1.2 4.8 9.2 0.7 -3.0
Average weekly red wine intake 0.5 0.8 1.2 -1.1 -0.5
Handedness (chirality/laterality): Left-handed 0.5 0.6 1.1 0.0 1.1
Mood swings 0.3 0.6 0.7 -0.8 -0.7
Loneliness, isolation 0.4 0.5 1.0 -0.3 -1.0
Long-standing illness, disability or infirmity 0.6 0.9 1.5 -1.2 -0.5
Ever had bowel cancer screening 0.2 0.2 0.4 -0.6 -0.3
Diabetes diagnosed by doctor 0.5 0.8 1.3 -0.6 -1.1
Ever had stillbirth, spontaneous miscarriage or termination 1.3 1.4 2.7 -0.3 -1.6
Friendships satisfaction 0.3 0.3 0.4 -0.6 0.6
Qualifications: nursing, teaching 0.4 0.7 1.3 1.2 -0.0
Commuting to job workplace: Walk 1.5 1.6 2.6 -0.8 1.6
Eye problems/disorders: Cataract 0.1 0.1 0.2 -0.3 0.4
Mouth/teeth dental problems: Mouth ulcers 0.4 0.7 1.1 1.0 0.6
Medication for cholesterol 0.3 0.4 0.4 0.6 -0.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.3 0.5 0.7 -0.3
Back pain experienced in last month 0.4 0.6 1.1 1.1 -0.0
Mineral and other dietary supplements 0.8 1.1 2.1 0.1 -1.4
Breast cancer (self-reported) 1.7 2.1 3.5 1.9 0.8
Asthma (self-reported) 0.3 0.5 0.6 0.7 0.7
Osteoporosis (self-reported) 0.9 1.1 1.1 -1.0 -1.1
Osteoarthritis (self-reported) 0.1 0.1 0.3 -0.5 0.1
Medication: Aspirin 0.1 0.2 0.3 -0.6 -0.0
Medication: Gliclazide 1.0 1.1 1.2 -1.1 -1.0
Illnesses of father: None of the above (group 1) 0.8 0.9 1.6 -0.5 -1.3
Smoking status: Current 0.2 0.4 0.7 -0.8 -0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.2 2.5 4.6 -0.6 2.1
Whole body water mass 0.2 0.9 1.7 -0.4 -1.3
Leg predicted mass (right) 0.1 0.7 1.1 -0.4 -1.1
Arm fat mass (left) 1.1 4.6 9.2 0.2 -3.0
Number of self-reported non-cancer illnesses 0.3 0.5 1.1 -1.0 0.0
Average weekly champagne plus white wine intake 0.1 0.2 0.3 -0.2 -0.5
Miserableness 0.8 1.4 2.7 -1.6 -0.4
Guilty feelings 0.4 0.5 0.6 -0.8 -0.7
Wears glasses or contact lenses 0.0 0.1 0.1 0.1 -0.3
Ever taken oral contraceptive pill 0.1 0.1 0.2 0.4 -0.2
Hearing aid user 0.6 0.7 1.4 1.2 0.0
Mother’s age at death 1.0 1.2 2.1 -1.4 0.6
Financial situation satisfaction 2.2 2.8 5.3 -2.3 0.4
Tinnitus: Yes, now most or all of the time 1.9 2.2 3.6 0.9 1.9
Commuting to job workplace: Public transport 2.8 3.4 5.2 -2.3 -1.2
Eye problems/disorders: Glaucoma 1.7 2.0 4.0 -0.2 -2.0
Medication: Blood pressure 0.3 0.6 0.9 1.0 0.4
Pain type(s) experienced in last month: Hip pain 0.9 1.1 2.2 -0.1 -1.5
Supplements: Fish oil (including cod liver oil) 1.2 1.6 3.1 0.4 1.8
High cholesterol (Self-reported) 1.1 2.0 2.4 1.5 1.3
Medication: Bendroflumethiazide 1.2 1.9 3.0 0.9 1.7
Medication: Paracetamol 1.0 1.6 2.5 0.8 1.6
Medication: Lisinopril 0.3 0.4 0.8 -0.0 0.9
Medication: Atorvastatin 3.6 4.4 6.2 -1.6 -2.5
Illnesses of father: High blood pressure 2.2 2.8 5.5 -0.3 2.3
Alcohol drinker status: Never 1.0 1.2 2.3 0.4 1.5
Ever smoked 0.8 1.3 1.9 -1.4 -0.9
Basal metabolic rate 0.2 1.3 2.5 -0.2 -1.6
Leg fat percentage (left) 1.3 4.7 6.1 1.8 -2.5
Arm fat-free mass (left) 0.1 0.6 1.3 -0.0 -1.1
Number of operations (self-reported) 1.2 1.9 3.3 -1.8 -0.6
Average weekly beer plus cider intake 0.6 0.8 1.5 0.3 -1.2
Irritability 0.7 1.1 2.0 -0.5 1.4
Risk taking 0.1 0.2 0.3 0.1 0.5
Ever had prostate specific antigen (PSA) test 1.2 1.3 2.7 1.6 -0.0
Fractured/broken bones in last 5 years 1.0 1.3 1.9 -1.4 -0.8
Age started oral contraceptive pill 2.7 3.4 6.7 -0.0 2.6
Diastolic blood pressure, automated reading 0.1 0.2 0.4 0.2 0.6
Ever depressed for a whole week 3.0 3.7 6.5 -2.5 -0.9
Unable to work because of sickness or disability 0.7 0.9 1.8 0.1 -1.4
Commuting to job workplace: Cycle 2.5 3.1 6.2 -0.0 2.5
Myopia 0.4 0.5 0.9 -0.4 1.0
Vascular/heart problems diagnosed by doctor 0.1 0.2 0.3 -0.0 0.6
Cholesterol lowering medication 1.8 2.6 5.2 0.2 2.3
Medication: Omeprazole (e.g. Zanprol) 1.8 2.2 3.2 1.1 -1.8
Pain experienced in last month 0.1 0.1 0.2 -0.5 -0.0
Supplements: Calcium 0.3 0.4 0.8 -0.9 0.0
Basal cell carcinoma (self-reported) 1.7 2.1 3.0 -1.1 -1.7
Heart attack/myocardial infarction (self-reported) 0.4 0.5 0.6 0.6 -0.8
Deep venous thrombosis (DVT) (self-reported) 1.7 2.1 4.0 0.5 -2.0
Heart disease (siblings) 0.7 0.8 1.2 -1.1 -0.6
Alcohol drinker status: Previous 0.3 0.3 0.6 0.2 0.8
Pack years of smoking 4.4 6.5 8.0 -2.8 -2.2
Impedance of whole body 0.6 3.2 6.3 -0.3 2.5
Leg fat mass (left) 0.9 3.5 5.7 1.1 -2.4
Arm predicted mass (left) 0.1 0.6 1.3 -0.0 -1.1