Hub : Genes

CNNM2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Stomach 0.11 0.072 6.7e-03 0.024 NA 0.068 NA -0.002 2.4e-02 NA 3.6e-04 NA 4.4e-01
2 ROSMAP Brain Pre-frontal Cortex 0.11 0.031 3.1e-08 0.084 0.06 0.069 0.067 0.070 6.0e-11 3.2e-08 2.8e-09 5.7e-09 2.2e-09

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Alzheimer’s Disease (in mother) 0.4 0.4 0.7 -0.8 0.4
Alzheimer’s Disease (in father) 0.6 0.7 0.8 -0.9 -0.8
Alzheimer’s Disease (including proxy) 0.5 0.7 1.3 -1.1 -0.4
Crohns Disease (2017) 0.4 0.8 1.2 -1.1 0.6
Irritable Bowel Disease (IBD) 0.9 2.2 3.6 -1.9 0.9
Ulcerative Colitis (UC) 1.3 2.4 4.6 -2.2 0.3
Major Depression (MDD) 8.9 11.0 18.2 1.9 -4.3
Reaction Time 3.3 6.3 10.3 -3.2 -1.5
Verbal and Numeric Reasoning (VNR) 1.2 2.8 4.7 2.2 1.0
Breast Cancer 0.6 1.4 2.5 -1.6 0.6
Ovarian Cancer 0.4 0.5 1.0 0.2 1.0
Prostate Cancer 2.3 3.3 6.7 -2.6 0.2
Age at First Birth 1.4 2.1 4.1 -0.2 2.0
Bipolar Disorder 7.1 7.0 7.5 2.6 -2.7
Body Mass Index (BMI) (2010) 6.4 8.9 16.8 -1.0 4.1
Coronary Artery Disease (CAD) 8.8 10.7 21.2 0.5 -4.6
Crohns Disease (2012) 1.4 2.3 4.6 2.1 -0.3
Mean Putamen Volume 1.4 1.6 2.4 1.6 0.9
Fasting Glucose 0.5 0.6 1.2 1.1 0.3
HbA1C 0.9 1.0 1.5 -1.2 -0.7
HDL Cholesterol 0.6 1.0 1.1 1.0 -1.0
LDL Cholesterol 0.1 0.2 0.3 0.2 -0.5
Lupus 2.0 3.0 4.3 2.1 1.3
Neuroticism 3.1 4.6 5.1 -2.0 -2.2
Primary Biliary Cirrhosis 0.2 0.3 0.5 0.3 -0.7
Rheumatoid Arthritis 0.1 0.2 0.2 0.5 -0.4
Schizophrenia 12.2 27.1 53.9 0.5 -7.3
Triglycerides 0.8 1.3 1.5 1.0 -1.2
Type 2 Diabetes (T2D) 0.3 0.3 0.6 -0.1 -0.8
Ulcerative Colitis 4.6 6.8 12.0 3.5 -1.3
Blood Eosinophil Count 0.7 5.8 11.2 3.4 -0.5
Blood Platelet Count 1.5 17.3 34.4 5.9 0.4
Blood Red Count 2.6 26.0 49.6 1.6 -7.0
Blood White Count 3.6 26.8 37.2 6.1 -4.0
Heel T-Score 1.6 12.4 24.2 -0.8 4.9
BMI 4.8 28.3 52.1 -2.1 7.2
Height 3.4 66.2 118.8 10.9 3.7
Waist Hip Ratio (WHR) 0.2 1.1 2.1 0.0 -1.5
Systolic Blood Pressure 23.0 116.7 232.3 1.1 -15.2
Smoking Status 5.8 14.0 19.8 4.5 2.9
Allergy or Eczema 4.7 12.2 23.9 -4.9 0.7
Cardiovascular Disease 11.5 38.3 65.9 3.3 -8.1
Hypothyroidism (self reported) 0.6 1.3 1.4 1.1 1.2
Respiratory disease 2.5 5.4 9.5 -3.1 1.1
Type 2 Diabetes (T2D) 1.8 3.3 6.4 0.4 2.5
Lung FEV1/FVC ratio 0.7 3.6 7.1 -0.4 2.7
Lung FVC 1.4 7.6 15.1 0.3 -3.9
Neuroticism 6.8 16.6 32.5 -0.9 -5.7
Chronotype (morning person) 0.4 0.9 1.2 1.1 0.8
Hair Pigment 0.1 1.9 2.1 -1.4 -1.3
Tanning 0.5 7.3 9.7 3.1 2.2
Hand grip strength (left) 3.3 8.7 14.0 -3.7 -1.9
Number of treatments/medications taken 2.5 4.5 7.7 -1.1 2.8
Average weekly spirits intake 0.6 0.8 1.6 -0.1 -1.3
Sensitivity / hurt feelings 2.1 3.7 6.4 -1.0 2.5
Frequency of depressed mood in last 2 weeks 3.0 4.2 5.3 -2.3 1.8
Hearing difficulty/problems: Yes 2.5 3.8 6.2 -2.5 1.2
Relative age of first facial hair 0.2 0.5 0.7 -0.8 -0.6
Other serious medical condition/disability diagnosed by doctor 2.6 3.4 4.4 -1.6 2.1
Ever used hormone-replacement therapy (HRT) 2.0 2.6 2.9 1.5 1.7
Ever had hysterectomy (womb removed) 0.3 0.4 0.7 0.9 -0.1
Systolic blood pressure, automated reading 17.9 52.9 105.4 -0.6 10.3
Eye problems/disorders: Diabetes related eye disease 0.3 0.3 0.3 -0.6 -0.5
Angina 4.5 5.8 8.1 -1.9 2.9
Medication for hormone replacement therapy 0.1 0.2 0.2 -0.4 -0.4
Vitamin and mineral supplements 0.6 0.8 1.5 1.2 0.3
Supplements: Zinc 2.6 2.8 5.6 -2.4 -0.0
Medication: Co-codamol 1.5 1.7 3.1 0.6 1.8
Medication: Metformin 2.2 3.0 5.9 -0.4 -2.4
Diabetes (father) 0.3 0.4 0.7 -0.4 -0.8
Diabetes (mother) 1.9 2.4 3.8 -1.0 -1.9
Severe depression (siblings) 2.8 3.2 6.3 -0.2 2.5
Pack years adult smoking proportion 0.6 0.9 1.6 -1.3 -0.4
Impedance of leg (right) 7.2 35.5 63.1 -2.8 7.9
Leg fat-free mass (left) 5.9 32.1 57.9 -2.5 -7.6
Trunk fat percentage 1.5 6.1 11.6 -0.7 -3.4
Hand grip strength (right) 2.1 5.8 8.5 -2.9 -1.7
Townsend deprivation index at recruitment 3.4 4.8 5.5 -2.0 -2.3
Current tobacco smoking 4.1 6.7 10.0 -3.2 -1.9
Average weekly fortified wine intake 1.7 2.0 3.6 1.9 -0.6
Maternal smoking around birth 4.1 5.9 9.4 -3.1 -1.5
Fed-up feelings 0.7 1.3 2.2 1.5 -0.6
Frequency of unenthusiasm / disinterest in last 2 weeks 1.0 1.3 2.2 -1.5 0.7
Relative age voice broke 0.2 0.3 0.5 -0.3 0.7
Taking other prescription medications 0.5 0.7 0.9 -0.7 1.0
Age when periods started (menarche) 2.0 4.8 7.4 -1.4 -2.7
Bilateral oophorectomy (both ovaries removed) 2.2 2.5 5.0 -0.2 2.2
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.7 1.4 -0.2 -1.2
Tinnitus: Yes, but not now, but have in the past 0.1 0.1 0.1 -0.3 0.3
Qualifications: CSEs or equivalent 0.2 0.3 0.6 0.1 -0.8
Serious illness, injury or assault to yourself 2.4 2.9 5.4 -0.6 2.3
High blood pressure 12.1 34.2 55.2 -3.6 7.4
Hayfever, allergic rhinitis or eczema 4.8 10.3 20.5 4.5 -0.4
Multivitamins +/- minerals 1.2 1.5 3.0 -1.7 -0.0
Stomach or abdominal pain in last month 0.1 0.1 0.2 0.0 -0.4
Supplements: Glucosamine 2.3 3.0 5.8 -2.4 0.3
Diverticular disease/diverticulitis (self-reported) 0.1 0.1 0.1 0.3 -0.2
Medication: Atenolol 5.2 6.5 7.5 -2.4 2.7
Medication: Levothyroxine sodium 0.2 0.3 0.3 -0.6 0.6
Sitting height 5.6 40.3 77.0 -8.8 1.9
Chronic bronchitis/emphysema (father) 1.0 1.2 2.3 1.5 0.2
High blood pressure (mother) 9.5 13.3 26.6 -0.2 5.2
Body mass index (BMI) 3.1 13.5 26.5 0.7 -5.1
Impedance of leg (left) 7.6 37.4 64.7 -3.2 8.0
Leg predicted mass (left) 5.8 31.2 56.0 -2.5 -7.5
Trunk fat mass 3.1 13.8 23.2 -2.1 -4.8
Waist circumference 2.2 8.4 14.1 -1.7 -3.8
Number of incorrect matches in round 1.2 2.0 3.9 -0.0 2.0
Past tobacco smoking 4.6 8.7 16.2 4.0 1.1
Alcohol usually taken with meals 0.7 1.1 1.7 1.3 0.7
Nervous feelings 7.7 14.6 28.6 0.8 5.3
Frequency of tenseness / restlessness in last 2 weeks 6.2 9.8 19.5 -0.3 4.4
Hearing difficulty/problems with background noise 7.7 12.4 22.9 -4.8 1.4
Hair/balding pattern: Pattern 2 1.7 2.1 4.1 0.4 -2.0
Had menopause 2.5 3.1 4.2 1.4 2.1
Had other major operations 0.5 0.6 1.1 0.4 1.1
Forced vital capacity (FVC) 3.3 13.0 21.5 -4.6 2.1
Heel bone mineral density (BMD) T-score, automated (right) 0.8 1.8 3.1 -0.7 -1.8
Ever unenthusiastic/disinterested for a whole week 1.7 2.1 2.7 -1.2 1.6
Qualifications: None of the above 0.0 0.0 0.0 -0.1 0.0
Financial difficulties in last 2 years 1.5 2.1 4.2 -2.0 0.2
Mouth/teeth dental problems 0.5 0.7 0.9 -0.7 1.0
Heart attack 4.5 5.7 9.8 -1.3 3.1
Allergy 5.5 12.5 24.6 -5.0 0.7
Pain all over the body in last month 0.3 0.3 0.4 0.5 0.6
Diabetes (self-reported) 1.9 2.9 4.8 -1.0 -2.2
Hayfever/allergic rhinitis (self-reported) 4.6 6.1 12.1 3.5 -0.3
Medication: Ramipril 4.2 5.5 10.2 0.8 3.2
Medication: Simvastatin 0.4 0.6 0.8 -0.9 0.6
Fluid intelligence score 1.2 2.5 2.8 -1.7 -1.5
Illnesses of siblings 1.6 2.3 3.9 0.8 -2.0
Neuroticism score 3.3 6.9 13.7 0.5 3.7
Weight 4.4 22.1 33.0 -3.4 -5.7
Impedance of arm (right) 1.2 5.6 11.2 -0.1 3.3
Arm fat percentage (right) 2.2 9.0 18.0 0.1 -4.2
Trunk fat-free mass 4.1 24.1 25.4 -4.8 -5.0
Hip circumference 3.6 16.1 26.1 -2.5 -5.1
Time employed in main current job 0.1 0.1 0.2 0.2 0.5
Alcohol intake versus 10 years previously 1.4 2.1 3.2 -1.8 -1.0
Father’s age at death 0.2 0.3 0.5 0.7 -0.2
Worrier / anxious feelings 7.5 14.3 26.5 1.5 5.2
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.5 0.6 -0.7 -0.8
Falls in the last year 1.5 2.0 2.9 -1.1 1.7
Hair/balding pattern: Pattern 3 2.3 3.5 4.7 -1.5 2.2
Number of live births 2.0 2.8 5.3 -0.6 2.3
Forced expiratory volume in 1-second (FEV1) 2.0 7.0 11.7 -3.4 1.5
Pulse rate 1.5 2.5 3.3 1.8 1.3
Happiness 0.0 0.0 0.0 -0.0 0.1
Noisy workplace 1.1 1.3 2.6 -1.6 -0.1
Qualifications: A levels/AS levels or equivalent 0.6 1.4 2.7 -1.6 0.4
Serious illness, injury or assault of a close relative in last 2 years 0.9 1.1 2.0 0.4 1.4
Mouth/teeth dental problems: Dentures 0.9 1.5 3.0 0.1 -1.7
Asthma 2.1 4.1 7.6 2.8 -0.8
Medication: Ibuprofen (e.g. Nurofen) 0.1 0.1 0.2 0.4 0.2
Medication: Cholesterol lowering 0.7 1.0 1.3 -0.9 1.1
Depression (self-reported) 0.6 0.7 1.2 -1.1 0.4
Medication: Lansoprazole 0.2 0.2 0.4 -0.3 0.6
Prospective memory result 0.9 1.2 2.1 1.5 -0.4
Lung cancer (father) 3.9 4.5 6.4 -1.6 -2.5
Illnesses of mother 3.4 4.2 7.1 1.1 -2.7
Forced expiratory volume in 1-second (FEV1), Best measure 1.7 5.5 9.3 -3.0 1.3
Pulse wave Arterial Stiffness index 3.8 4.5 4.6 2.1 2.1
Impedance of arm (left) 1.3 6.1 12.1 -0.1 3.5
Arm fat mass (right) 3.0 12.6 23.8 -1.2 -4.9
Trunk predicted mass 4.2 24.5 26.0 -4.8 -5.1
Standing height 4.2 42.7 80.3 -9.0 -2.3
Length of working week for main job 1.7 1.9 3.3 -1.8 -0.6
Exposure to tobacco smoke at home 2.1 2.4 4.3 -0.7 -2.1
Breastfed as a baby 2.1 2.6 4.9 0.6 2.2
Tense / ‘highly strung’ 6.1 10.2 18.5 -1.4 4.3
Seen doctor (GP) for nerves, anxiety, tension or depression 3.9 5.9 9.8 -1.4 3.1
Hair/balding pattern: Pattern 4 0.7 1.7 2.4 1.0 -1.6
Birth weight of first child 7.2 13.1 15.5 -3.9 -3.3
Peak expiratory flow (PEF) 1.9 4.5 7.2 -2.7 -1.3
Pulse wave reflection index 2.7 3.4 6.7 -0.2 -2.6
Ever highly irritable/argumentative for 2 days 3.3 4.0 4.2 -1.9 2.1
Loud music exposure frequency 1.6 1.7 3.4 -1.8 0.2
Qualifications: O levels/GCSEs or equivalent 0.3 0.5 0.8 -0.9 0.5
Mouth/teeth dental problems: Bleeding gums 0.5 0.7 1.3 0.3 -1.1
Blood clot in the leg (DVT) 1.7 2.2 4.3 2.1 0.3
Medication: Paracetamol 0.8 1.4 2.8 -0.2 1.7
Headache pain in last month 0.1 0.2 0.3 -0.4 -0.6
Medication for cholesterol, blood pressure or diabetes 2.4 4.0 7.3 0.9 -2.7
Glaucoma (self-reported) 0.8 1.0 1.8 0.3 1.4
Gout (self-reported) 0.4 0.6 0.7 -0.6 0.8
Hypothyroidism/myxoedema (self-reported) 0.2 0.5 0.9 -0.9 0.2
Medication: Amlodipine 2.4 3.4 6.6 -0.3 2.6
Medication: Ventolin 100micrograms inhaler 1.1 1.4 2.2 1.5 -0.8
Birth weight 8.5 18.4 28.6 -2.9 -5.3
Chronic bronchitis/emphysema (mother) 0.4 0.5 0.7 -0.4 -0.9
High blood pressure (siblings) 2.9 4.2 7.8 -0.8 2.8
Forced vital capacity (FVC), Best measure 2.4 8.8 14.9 -3.9 1.7
Body fat percentage 1.2 4.7 8.6 -0.9 -2.9
Leg fat percentage (right) 0.7 2.8 3.9 -1.2 -2.0
Arm fat-free mass (right) 3.9 20.2 22.8 -4.2 -4.8
Exposure to tobacco smoke outside home 5.3 7.0 9.0 -3.0 -2.3
Comparative body size at age 10 2.0 5.7 11.2 -0.3 -3.4
Number of full brothers 0.5 0.6 0.8 -0.6 0.9
Worry too long after embarrassment 3.0 5.1 8.4 1.4 2.9
Seen a psychiatrist for nerves, anxiety, tension or depression 4.5 5.9 11.7 -0.0 3.4
Wheeze or whistling in the chest in last year 1.9 3.4 3.7 1.9 -1.8
Number of children fathered 0.8 0.9 1.7 -1.3 0.2
Reason for reducing amount of alcohol drunk: Health precaution 1.2 1.4 2.5 -0.6 1.6
Age at first live birth 1.5 2.7 3.6 1.3 -1.9
Pulse wave peak to peak time 5.6 6.6 6.9 -2.6 -2.5
Health satisfaction 1.3 1.7 3.4 -1.9 0.0
Shortness of breath walking on level ground 0.3 0.4 0.6 0.8 -0.3
Qualifications: College or University degree 0.2 0.7 1.3 -0.2 1.2
Eye problems/disorders: None of the above 0.3 0.3 0.6 -0.2 -0.8
Mouth/teeth dental problems: Loose teeth 4.2 4.9 6.1 2.5 -1.9
Emphysema/chronic bronchitis 0.6 0.7 1.3 -0.2 -1.2
Medication for pain relief, constipation, heartburn 1.1 1.9 3.9 0.1 -2.0
Neck or shoulder pain in last month 4.4 6.2 7.4 -2.2 2.7
Medication: Blood pressure 3.4 6.1 11.5 -0.8 3.4
Angina (self-reported) 5.8 7.5 11.0 -2.0 3.3
Migraine (self-reported) 5.0 6.3 12.2 -0.6 -3.5
Medication: Ibuprofen 0.1 0.1 0.2 0.4 0.3
Medication: Allopurinol 1.0 1.3 1.4 -1.2 1.1
Medication: Omeprazole 0.1 0.1 0.3 -0.0 0.5
Medication: Seretide 50 evohaler 1.8 2.1 3.0 1.1 -1.7
Mean time to correctly identify matches 1.9 3.7 4.6 2.1 1.7
Heart disease (mother) 1.4 1.7 3.1 -0.5 1.8
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.0 0.0 0.0 0.1 0.0
Whole body fat mass 3.0 12.8 22.0 -1.9 -4.7
Leg fat mass (right) 3.1 12.3 18.8 -2.4 -4.3
Arm predicted mass (right) 3.8 19.7 21.9 -4.2 -4.7
Pulse rate, automated reading 1.8 5.9 11.7 -0.2 3.4
Alcohol intake frequency. 2.7 6.5 12.9 -3.6 0.3
Comparative height size at age 10 4.2 23.8 33.8 -5.8 -3.7
Number of full sisters 0.8 0.9 1.7 -0.3 -1.3
Suffer from ‘nerves’ 4.2 6.7 13.3 -0.1 3.6
Overall health rating 1.2 2.5 4.3 -2.1 0.8
Chest pain or discomfort 0.7 1.0 1.9 -0.5 1.4
Had major operations 0.8 0.9 1.1 -1.1 -0.9
Age at last live birth 0.7 1.1 1.9 0.5 -1.4
Family relationship satisfaction 1.2 1.5 1.8 -1.1 1.4
Leg pain on walking 0.6 0.8 1.6 -0.1 1.3
Qualifications: NVQ or HND or HNC or equivalent 0.1 0.1 0.1 -0.4 0.2
Commuting to job workplace: Car/motor vehicle 0.4 0.4 0.8 0.3 -0.9
Illness, injury, bereavement, stress in last 2 years 4.4 5.3 6.8 2.0 -2.6
Medication: Aspirin 4.3 5.7 6.5 -2.2 2.5
Supplements: Vitamin C 0.5 0.6 1.2 0.1 -1.1
Knee pain experienced in last month 1.6 2.5 2.5 -1.6 -1.6
Hypertension (Self-reported) 11.1 31.2 52.0 -3.2 7.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.9 1.0 1.7 -1.3 0.6
Illnesses of father: Heart disease 5.5 7.5 13.4 -1.3 3.7
Illnesses of siblings: Diabetes 2.3 2.9 4.4 -1.1 -2.1
Smoking status: Previous 1.8 2.8 5.3 -2.3 0.5
Forced expiratory volume in 1-second (FEV1), predicted 5.8 12.2 22.9 -4.8 -1.2
Whole body fat-free mass 4.7 27.3 39.3 -3.9 -6.3
Leg fat-free mass (right) 5.7 31.1 55.7 -2.6 -7.5
Arm fat percentage (left) 2.2 8.9 17.8 0.2 -4.2
Average weekly red wine intake 0.5 0.7 1.0 1.0 0.7
Handedness (chirality/laterality): Left-handed 0.2 0.3 0.3 0.5 -0.6
Mood swings 0.4 0.7 1.0 0.7 1.0
Loneliness, isolation 0.0 0.0 0.1 0.3 -0.1
Long-standing illness, disability or infirmity 2.5 3.9 5.8 -2.4 1.4
Ever had bowel cancer screening 1.0 1.1 2.0 -1.4 0.5
Diabetes diagnosed by doctor 2.2 3.6 5.8 -1.2 -2.4
Ever had stillbirth, spontaneous miscarriage or termination 0.2 0.3 0.3 0.5 -0.5
Friendships satisfaction 0.3 0.4 0.6 0.4 -0.8
Qualifications: nursing, teaching 0.0 0.1 0.1 -0.1 0.3
Commuting to job workplace: Walk 3.8 4.1 8.1 -0.3 2.8
Eye problems/disorders: Cataract 0.4 0.4 0.9 0.1 -0.9
Mouth/teeth dental problems: Mouth ulcers 0.5 0.8 1.4 1.2 -0.5
Medication for cholesterol 4.9 7.5 12.2 1.7 -3.5
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.5 0.6 1.0 0.3 1.0
Back pain experienced in last month 2.2 3.2 5.0 -2.2 1.2
Mineral and other dietary supplements 3.2 4.3 7.6 2.8 1.0
Breast cancer (self-reported) 0.1 0.1 0.2 -0.0 0.4
Asthma (self-reported) 1.8 3.5 6.6 2.6 -0.7
Osteoporosis (self-reported) 1.5 1.9 3.4 0.5 1.8
Osteoarthritis (self-reported) 1.0 1.2 2.3 0.4 1.5
Medication: Aspirin 5.5 7.2 8.2 -2.5 2.9
Medication: Gliclazide 0.5 0.6 1.1 -1.1 0.1
Illnesses of father: None of the above (group 1) 5.2 6.3 12.7 -0.1 -3.6
Smoking status: Current 4.4 7.0 9.9 -3.1 -2.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.3 2.9 4.4 -1.2 2.1
Whole body water mass 4.6 26.9 38.4 -3.9 -6.2
Leg predicted mass (right) 5.7 31.1 56.0 -2.5 -7.5
Arm fat mass (left) 3.1 12.9 24.6 -1.1 -5.0
Number of self-reported non-cancer illnesses 0.8 1.5 2.8 0.4 1.7
Average weekly champagne plus white wine intake 1.4 1.9 3.8 0.2 -1.9
Miserableness 2.5 4.4 8.7 -3.0 -0.1
Guilty feelings 0.2 0.4 0.7 0.9 0.1
Wears glasses or contact lenses 0.7 0.9 1.7 -0.0 1.3
Ever taken oral contraceptive pill 2.7 3.0 5.9 -0.4 -2.4
Hearing aid user 0.2 0.2 0.3 -0.6 -0.1
Mother’s age at death 0.6 0.7 1.3 -1.1 0.5
Financial situation satisfaction 1.6 1.9 2.2 -1.3 -1.5
Tinnitus: Yes, now most or all of the time 0.5 0.6 0.6 0.7 -0.8
Commuting to job workplace: Public transport 0.5 0.7 0.7 -0.8 0.8
Eye problems/disorders: Glaucoma 0.5 0.6 1.0 0.3 1.0
Medication: Blood pressure 9.1 17.5 28.1 -2.6 5.3
Pain type(s) experienced in last month: Hip pain 0.4 0.5 0.6 0.5 0.8
Supplements: Fish oil (including cod liver oil) 1.5 2.0 4.0 -2.0 -0.2
High cholesterol (Self-reported) 0.5 0.8 1.0 -1.0 0.9
Medication: Bendroflumethiazide 3.1 4.7 6.9 -1.6 2.6
Medication: Paracetamol 1.0 1.6 3.2 0.0 1.8
Medication: Lisinopril 3.1 4.0 7.0 -1.0 2.6
Medication: Atorvastatin 4.4 5.4 8.6 -1.5 2.9
Illnesses of father: High blood pressure 3.2 4.0 7.2 -0.9 2.7
Alcohol drinker status: Never 0.1 0.2 0.2 -0.5 0.3
Ever smoked 3.6 6.4 11.0 -3.3 -1.4
Basal metabolic rate 4.7 26.4 38.6 -3.8 -6.2
Leg fat percentage (left) 0.8 3.1 4.2 -1.4 -2.0
Arm fat-free mass (left) 4.1 21.2 24.8 -4.2 -5.0
Number of operations (self-reported) 0.3 0.5 0.6 -0.8 -0.6
Average weekly beer plus cider intake 0.9 1.3 2.6 0.0 -1.6
Irritability 1.4 2.5 4.4 -2.1 0.8
Risk taking 0.8 1.2 2.3 -1.5 -0.2
Ever had prostate specific antigen (PSA) test 0.6 0.7 1.1 1.0 0.6
Fractured/broken bones in last 5 years 1.7 2.2 4.4 0.2 2.1
Age started oral contraceptive pill 0.3 0.3 0.4 -0.6 0.5
Diastolic blood pressure, automated reading 11.6 36.5 60.4 -3.6 7.8
Ever depressed for a whole week 2.7 3.3 4.0 -1.6 2.0
Unable to work because of sickness or disability 1.8 2.3 2.9 -1.3 1.7
Commuting to job workplace: Cycle 1.0 1.2 2.2 0.4 1.5
Myopia 0.0 0.1 0.1 0.2 0.3
Vascular/heart problems diagnosed by doctor 12.8 35.3 57.9 3.6 -7.6
Cholesterol lowering medication 1.5 2.1 4.2 -0.3 2.0
Medication: Omeprazole (e.g. Zanprol) 0.1 0.2 0.2 0.4 0.4
Pain experienced in last month 1.0 1.7 2.1 1.4 -1.1
Supplements: Calcium 0.6 0.7 0.8 -0.9 0.8
Basal cell carcinoma (self-reported) 0.5 0.5 1.0 -1.0 -0.4
Heart attack/myocardial infarction (self-reported) 4.2 5.3 9.4 -1.1 3.1
Deep venous thrombosis (DVT) (self-reported) 1.5 1.9 3.6 1.9 0.4
Heart disease (siblings) 5.1 6.3 11.0 -1.3 3.3
Alcohol drinker status: Previous 0.7 0.8 1.4 -1.2 0.5
Pack years of smoking 0.8 1.1 2.1 -1.4 -0.4
Impedance of whole body 3.9 20.1 37.4 -1.7 6.1
Leg fat mass (left) 3.0 12.1 18.2 -2.5 -4.3
Arm predicted mass (left) 3.8 20.0 24.5 -3.9 -4.9