Hub : Genes

CTC-429P9.1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.0990 0.0360 3.2e-03 0.020 NA 0.015 NA 0.010 7.8e-03 NA 1.9e-02 NA 4.4e-02
2 GTEx Breast Mammary Tissue (Male) 0.1829 0.1377 1.9e-01 0.019 NA -0.003 NA -0.004 1.2e-01 NA 3.8e-01 NA 4.0e-01
3 GTEx Breast Mammary Tissue (Female) 0.2446 0.0942 1.5e-02 -0.004 NA 0.019 NA 0.012 4.6e-01 NA 8.9e-02 NA 1.4e-01
4 GTEx Cells Transformed fibroblasts 0.1380 0.0480 1.8e-03 0.055 NA 0.033 NA 0.022 5.9e-05 NA 1.6e-03 NA 8.1e-03
5 GTEx Muscle Skeletal 0.0934 0.0364 5.2e-03 0.001 NA 0.020 NA 0.016 2.6e-01 NA 3.8e-03 NA 8.4e-03
6 GTEx Nerve Tibial 0.1383 0.0434 5.3e-04 0.102 NA 0.082 NA 0.093 1.1e-07 NA 2.1e-06 NA 4.1e-07
7 GTEx Skin Not Sun Exposed Suprapubic 0.1900 0.0660 1.6e-03 0.018 NA 0.043 NA 0.035 3.5e-02 NA 2.1e-03 NA 4.9e-03
8 GTEx Skin Sun Exposed Lower leg 0.1490 0.0380 8.8e-06 0.081 NA 0.025 NA 0.038 3.2e-07 NA 3.4e-03 NA 4.1e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.6 0.9 2.8 -1.7 0.0 0.8 -1.1 -1.0 -0.7 0.3 -1.0
Bipolar Disorder or Schizophrenia 0.1 0.3 1.0 -0.1 0.0 0.8 -1.0 -0.2 -0.5 -0.6 -0.5
Depressed Affect (Nagel 2018) 0.5 0.9 2.2 -1.5 0.0 -1.1 -1.2 -1.4 -0.5 -0.6 -0.5
Depression (Nagel 2018) 0.2 0.3 1.5 -0.6 0.0 -1.2 0.2 -0.1 -0.2 0.4 0.2
Intelligence (Savage-Jansen 2018) 0.8 2.4 5.0 2.2 0.0 1.1 2.1 0.6 1.9 -0.3 2.1
Neuroticism (Nagel 2018) 0.4 0.9 3.3 -1.3 0.0 -1.1 -1.8 -0.5 -0.8 -0.3 -0.5
Schizophrenia (2018) 0.2 0.3 1.4 1.2 0.0 0.5 -0.3 0.5 0.0 -0.8 0.1
Schizophrenia vs Biploar Disorder 0.8 1.0 3.6 1.9 0.0 -1.0 1.1 0.2 0.5 -1.4 0.6
Worry (Nagel 2018) 0.5 1.1 4.0 -1.2 0.0 -0.9 -2.0 -0.6 -1.0 -0.1 -0.9
Alzheimer’s Disease (in mother) 0.5 0.6 1.8 -0.7 0.0 -1.3 -1.0 -0.8 -0.3 -0.6 -0.3
Alzheimer’s Disease (in father) 0.2 0.2 0.5 -0.5 0.0 -0.5 -0.7 0.6 -0.0 -0.6 0.0
Alzheimer’s Disease (including proxy) 0.5 0.8 2.6 -0.7 0.0 -1.0 -1.6 -0.9 -0.6 -0.8 -0.6
Crohns Disease (2017) 0.2 0.5 1.9 1.4 0.0 -0.8 0.6 0.8 0.5 0.0 0.7
Irritable Bowel Disease (IBD) 0.5 1.1 3.1 1.8 0.0 0.2 0.5 1.5 1.2 0.9 1.1
Ulcerative Colitis (UC) 0.3 0.6 1.9 0.8 0.0 0.1 -0.1 1.3 0.8 1.4 0.6
Major Depression (MDD) 0.2 0.3 1.5 -1.2 0.0 0.4 -0.4 0.0 -0.4 0.6 -0.1
Reaction Time 1.6 3.1 5.9 1.6 0.0 1.7 1.5 2.2 1.8 2.4 1.9
Verbal and Numeric Reasoning (VNR) 0.7 1.6 3.9 2.0 0.0 -0.6 1.4 1.1 1.4 0.4 1.8
Breast Cancer 0.3 0.7 2.2 -1.5 0.0 0.2 -1.3 0.1 -0.3 1.3 -0.4
Ovarian Cancer 0.2 0.3 1.6 0.5 0.0 -1.3 0.2 0.6 0.2 0.1 0.4
Prostate Cancer 1.8 2.5 9.1 3.0 0.0 0.1 1.8 1.3 1.4 -1.7 1.0
Age at First Birth 0.3 0.4 1.0 -1.0 0.0 0.9 -0.5 -0.2 -0.8 0.2 -0.5
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.0 0.1 0.3 -0.0 0.0 -0.1 -0.3 0.0 0.1 0.5 -0.3
Coronary Artery Disease (CAD) 0.7 0.9 5.4 -0.7 0.0 -0.8 0.6 -2.3 0.4 0.0 0.3
Crohns Disease (2012) 0.4 0.6 2.5 1.6 0.0 -0.8 0.8 -0.8 0.2 0.7 0.4
Mean Putamen Volume 0.8 0.9 3.2 -1.1 0.0 -1.3 -1.8 -0.2 -0.7 0.4 -0.7
Fasting Glucose 0.5 0.6 1.7 -1.1 0.0 -0.8 -0.4 -1.0 -0.1 1.3 -0.2
HbA1C 1.3 1.5 3.6 1.2 0.0 0.8 1.8 0.0 1.2 1.9 1.2
HDL Cholesterol 0.3 0.4 2.3 0.0 0.0 -0.8 -1.5 -0.6 -0.0 0.2 0.1
LDL Cholesterol 0.2 0.3 1.0 -0.1 0.0 0.5 0.6 -1.0 -0.0 -0.7 -0.8
Lupus 1.5 2.2 4.3 2.0 0.0 -1.5 1.7 0.8 1.7 -0.6 2.1
Neuroticism (2016) 1.1 1.5 3.1 -1.6 0.0 0.0 -1.3 -0.9 -1.8 -1.2 -1.6
Primary Biliary Cirrhosis 3.6 5.2 10.6 2.6 0.0 3.3 0.8 2.3 2.4 3.0 1.9
Rheumatoid Arthritis 0.3 0.4 1.1 1.0 0.0 -0.6 0.6 -0.1 0.2 0.8 0.6
Schizophrenia (2014) 0.2 0.4 1.5 1.0 0.0 0.6 -0.4 0.3 0.0 -1.2 -0.0
Triglycerides 0.4 0.6 2.4 -0.4 0.0 1.5 -0.3 1.4 0.4 0.3 -0.0
Type 2 Diabetes (T2D) (2012) 0.1 0.1 0.5 -0.7 0.0 -0.3 0.4 0.1 0.3 -0.2 -0.3
Ulcerative Colitis 1.0 1.4 4.2 1.3 0.0 0.5 1.2 2.1 1.5 0.2 1.3
Blood Eosinophil Count 0.6 4.8 11.9 -3.2 0.0 -1.1 0.7 -3.3 -1.9 3.5 -0.2
Blood Platelet Count 0.4 5.1 24.3 -4.9 0.0 3.7 1.2 -0.3 -0.4 1.0 -0.6
Blood Red Count 0.2 1.5 6.8 -1.4 0.0 -0.5 -0.6 -2.6 -1.0 0.5 -1.2
Blood White Count 1.1 8.5 30.9 0.1 0.0 5.6 -2.9 5.3 0.7 0.3 0.0
Heel T-Score 0.2 1.9 5.4 -1.4 0.0 -2.3 0.3 -0.8 -1.6 -1.5 -1.4
BMI 0.1 0.3 2.1 -0.0 0.0 -0.5 1.4 0.0 0.3 -0.4 0.1
Height 0.2 4.7 14.6 3.8 0.0 3.0 -0.8 0.4 2.4 0.1 2.8
Waist Hip Ratio (WHR) 0.3 1.5 10.0 -3.2 0.0 1.0 -0.0 -0.5 -0.9 0.2 -0.4
Systolic Blood Pressure 1.3 6.4 20.7 -0.7 0.0 4.5 1.4 1.6 2.8 3.4 2.6
Smoking Status 0.2 0.5 2.0 -0.3 0.0 1.4 0.9 0.1 0.5 0.7 0.4
Allergy or Eczema 0.4 1.1 6.4 0.1 0.0 0.0 2.5 -0.9 0.6 -0.2 1.0
Cardiovascular Disease 1.4 4.5 22.2 -2.3 0.0 4.7 0.6 -0.3 0.8 2.8 0.5
Hypothyroidism (self reported) 0.4 1.0 2.7 -1.5 0.0 -0.1 -0.2 -1.6 -0.5 1.4 -0.7
Respiratory disease 1.1 2.4 7.1 -2.7 0.0 -1.0 1.0 -1.8 -1.7 -1.7 -1.1
Type 2 Diabetes (T2D) (2018) 0.2 0.4 1.8 -1.4 0.0 1.0 -0.6 -0.4 -0.2 0.2 -0.2
Lung FEV1/FVC ratio 0.3 1.7 8.8 1.1 0.0 -0.1 1.3 3.0 0.7 -0.8 0.9
Lung FVC 0.5 2.7 7.8 -1.2 0.0 -1.5 -2.8 -1.1 -1.9 -0.6 -2.2
Neuroticism 0.9 2.2 5.4 -1.6 0.0 -2.3 -2.1 -1.2 -1.4 -0.8 -1.1
Chronotype (morning person) 0.2 0.5 2.5 -0.4 0.0 0.6 0.4 1.6 0.5 -0.5 0.6
Hair Pigment 0.0 0.8 2.3 1.0 0.0 -1.5 -0.0 -0.1 -0.4 -1.4 -0.6
Tanning 0.1 0.6 3.7 0.8 0.0 1.9 -0.2 0.5 0.6 -0.3 0.1
Hand grip strength (left) 0.2 0.5 2.8 0.6 0.0 -1.7 -0.1 -0.6 -0.5 -0.6 -0.2
Number of treatments/medications taken 0.4 0.7 3.5 -1.0 0.0 1.9 -0.3 -0.4 0.5 0.4 0.6
Average weekly spirits intake 0.8 1.0 2.6 1.0 0.0 0.3 0.5 -0.1 1.6 1.4 1.3
Sensitivity / hurt feelings 0.7 1.3 4.0 -1.5 0.0 -1.0 -2.0 -0.8 -1.0 -0.7 -1.0
Frequency of depressed mood in last 2 weeks 0.3 0.4 1.6 -0.6 0.0 -1.2 0.6 -0.5 -0.3 0.5 -0.2
Hearing difficulty/problems: Yes 1.4 2.2 7.5 -1.1 0.0 -0.5 -0.4 -1.8 -1.7 -2.7 -1.5
Relative age of first facial hair 0.3 0.6 4.4 0.6 0.0 -0.1 -0.5 -0.2 -0.2 -2.1 0.2
Other serious medical condition/disability diagnosed by doctor 0.2 0.2 0.8 -0.4 0.0 0.8 -0.9 0.3 -0.4 0.1 -0.4
Ever used hormone-replacement therapy (HRT) 0.2 0.3 1.7 -0.7 0.0 1.3 0.3 0.0 0.3 -0.0 0.1
Ever had hysterectomy (womb removed) 1.4 1.6 3.4 0.3 0.0 0.6 1.7 1.3 1.8 1.2 1.7
Systolic blood pressure, automated reading 0.9 2.7 10.4 -1.4 0.0 3.2 1.3 0.8 1.5 1.6 1.4
Eye problems/disorders: Diabetes related eye disease 0.3 0.4 0.7 0.8 0.0 0.5 -0.2 0.8 0.4 0.8 0.7
Angina 0.4 0.5 2.1 -1.0 0.0 1.4 -0.5 -0.4 0.3 0.8 0.1
Medication for hormone replacement therapy 0.5 0.6 1.5 0.5 0.0 1.2 0.3 1.0 0.8 0.8 0.8
Vitamin and mineral supplements 0.6 0.8 1.2 -1.1 0.0 1.0 -0.9 -1.0 -1.0 0.3 -1.1
Supplements: Zinc 0.4 0.4 1.3 0.0 0.0 -0.7 1.2 -1.1 0.0 0.7 -0.0
Medication: Co-codamol 0.2 0.2 0.6 -0.5 0.0 0.6 0.8 -0.2 -0.1 0.5 -0.1
Medication: Metformin 0.3 0.5 1.0 -1.0 0.0 0.4 -0.7 -0.9 -0.9 -0.4 -0.7
Diabetes (father) 0.4 0.4 1.2 -0.6 0.0 -0.4 -0.8 0.4 -0.7 1.1 -0.7
Diabetes (mother) 0.4 0.5 3.0 -1.7 0.0 -0.6 -0.5 -0.3 -0.3 0.6 -0.3
Severe depression (siblings) 2.0 2.2 4.0 1.8 0.0 -1.7 -0.1 1.9 1.3 2.0 1.6
Pack years adult smoking proportion 0.6 0.9 3.3 -0.7 0.0 -1.8 -1.0 -0.6 -0.9 -0.4 -1.0
Impedance of leg (right) 0.9 4.6 15.8 0.5 0.0 4.0 1.2 0.2 2.4 2.4 2.7
Leg fat-free mass (left) 0.3 1.5 7.9 1.5 0.0 -2.8 -0.6 -0.3 -0.5 -0.8 -0.4
Trunk fat percentage 0.2 0.8 2.2 -0.8 0.0 0.5 1.0 0.1 1.5 1.0 1.3
Hand grip strength (right) 0.4 1.2 4.0 0.9 0.0 -2.0 -0.6 -1.0 -1.2 -1.0 -0.8
Townsend deprivation index at recruitment 0.7 1.0 2.6 -1.3 0.0 -0.4 -0.9 0.5 -1.6 0.6 -1.5
Current tobacco smoking 0.3 0.5 1.5 0.1 0.0 0.1 1.1 -0.5 0.7 1.2 0.6
Average weekly fortified wine intake 0.2 0.3 1.3 0.1 0.0 0.1 1.1 -0.3 0.2 0.8 0.2
Maternal smoking around birth 0.3 0.5 2.5 -1.1 0.0 -0.4 -0.4 -0.3 0.1 1.6 -0.1
Fed-up feelings 0.3 0.6 2.8 -0.7 0.0 -0.9 0.1 -1.7 0.1 0.7 0.1
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 2.4 -0.6 0.0 -1.6 -0.6 0.3 -0.2 -0.2 -0.1
Relative age voice broke 0.4 0.6 1.6 1.0 0.0 0.7 0.6 0.2 0.6 -0.8 1.3
Taking other prescription medications 0.3 0.5 1.0 -0.9 0.0 1.0 0.7 -0.9 0.4 -0.1 0.5
Age when periods started (menarche) 1.0 2.3 8.9 1.8 0.0 0.7 0.9 3.0 1.6 0.4 1.6
Bilateral oophorectomy (both ovaries removed) 0.4 0.4 1.5 -0.6 0.0 0.3 0.8 0.0 0.7 1.2 0.6
Heel bone mineral density (BMD) T-score, automated (left) 0.6 1.5 2.9 -1.2 0.0 -1.4 -1.0 -0.5 -1.5 -1.7 -1.4
Tinnitus: Yes, but not now, but have in the past 0.2 0.2 0.6 -0.0 0.0 -0.8 0.5 0.4 -0.4 -0.4 -0.3
Qualifications: CSEs or equivalent 0.4 0.5 1.8 -0.3 0.0 -0.9 -1.4 -0.2 -0.9 0.2 -0.8
Serious illness, injury or assault to yourself 0.7 0.8 1.7 -1.2 0.0 -0.4 -0.7 -1.3 -1.2 0.2 -1.1
High blood pressure 1.9 5.4 24.7 -1.6 0.0 5.0 1.2 0.6 1.7 2.9 1.6
Hayfever, allergic rhinitis or eczema 0.7 1.6 7.7 0.7 0.0 -0.5 2.8 -0.3 1.2 0.4 1.5
Multivitamins +/- minerals 0.4 0.4 1.8 0.7 0.0 -1.3 -0.4 0.5 0.3 -0.8 0.3
Stomach or abdominal pain in last month 0.3 0.3 1.2 -0.7 0.0 -0.5 -0.7 1.1 -0.4 0.2 -0.2
Supplements: Glucosamine 2.8 3.6 6.3 -2.2 0.0 -2.5 -0.7 -1.9 -2.0 -2.3 -2.1
Diverticular disease/diverticulitis (self-reported) 0.6 0.7 2.4 1.3 0.0 -0.5 1.6 -0.4 0.7 0.3 0.9
Medication: Atenolol 0.5 0.6 4.2 -0.6 0.0 2.1 -0.0 -0.2 0.5 -0.1 0.4
Medication: Levothyroxine sodium 0.2 0.3 0.8 -0.7 0.0 0.3 0.4 -0.9 0.1 0.9 -0.1
Sitting height 0.1 1.0 4.2 0.8 0.0 -0.4 -1.3 -2.0 -0.8 0.7 -0.6
Chronic bronchitis/emphysema (father) 1.0 1.2 2.7 0.7 0.0 -0.0 1.6 0.1 1.4 1.6 1.4
High blood pressure (mother) 1.0 1.4 5.8 -1.4 0.0 -1.0 -0.9 -2.4 -0.9 0.7 -0.5
Body mass index (BMI) 0.2 0.8 2.8 -1.4 0.0 -1.7 0.2 -0.5 -0.5 -0.5 -0.8
Impedance of leg (left) 0.9 4.4 14.7 0.4 0.0 3.8 1.2 0.8 2.3 2.5 2.6
Leg predicted mass (left) 0.3 1.5 8.0 1.6 0.0 -2.8 -0.5 -0.3 -0.4 -0.7 -0.3
Trunk fat mass 0.1 0.6 1.8 -0.0 0.0 0.1 0.9 0.0 1.3 0.7 1.2
Waist circumference 0.2 0.8 3.4 -1.8 0.0 -1.1 0.4 -0.9 -0.4 -0.6 -0.4
Number of incorrect matches in round 0.6 1.0 4.5 -2.1 0.0 0.6 -0.4 1.0 -0.7 -1.1 -0.9
Past tobacco smoking 0.4 0.7 4.4 0.3 0.0 -2.1 -0.7 -0.3 -0.5 0.2 -0.5
Alcohol usually taken with meals 0.3 0.6 1.4 0.1 0.0 -1.0 1.2 1.0 0.2 -0.8 0.5
Nervous feelings 0.2 0.3 1.0 -0.4 0.0 0.9 -1.0 -0.7 -0.3 -0.0 -0.2
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.5 1.1 -0.9 0.0 -1.1 -0.8 -0.6 -0.7 0.5 -0.7
Hearing difficulty/problems with background noise 1.6 2.6 5.1 -1.8 0.0 -1.6 -1.3 -0.6 -2.3 -2.1 -1.9
Hair/balding pattern: Pattern 2 1.5 1.9 3.7 -1.9 0.0 -0.6 -1.1 -1.9 -1.5 0.9 -1.6
Had menopause 0.2 0.3 1.0 -0.3 0.0 0.7 0.7 -1.0 -0.0 0.1 0.0
Had other major operations 0.7 0.9 2.0 0.8 0.0 -0.3 0.4 1.4 1.0 1.2 1.4
Forced vital capacity (FVC) 0.3 1.2 1.9 1.3 0.0 -1.2 -1.4 -1.3 -1.2 0.2 -1.1
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.8 1.8 -1.3 0.0 -0.7 -1.1 -0.1 -1.1 -0.7 -1.0
Ever unenthusiastic/disinterested for a whole week 0.9 1.1 4.3 -0.6 0.0 -1.5 -2.1 -0.2 -1.0 0.1 -0.7
Qualifications: None of the above 0.9 1.9 4.6 -1.8 0.0 1.5 -1.5 -0.6 -0.7 -2.1 -1.3
Financial difficulties in last 2 years 2.4 3.2 6.7 -2.0 0.0 -1.5 -1.2 -2.0 -2.6 -1.1 -2.4
Mouth/teeth dental problems 0.6 0.9 3.7 -0.5 0.0 -0.5 -1.9 -0.3 -1.1 -0.2 -1.1
Heart attack 0.8 1.0 2.8 -0.1 0.0 1.6 -0.0 1.1 1.7 0.4 1.3
Allergy 0.5 1.1 3.0 1.4 0.0 0.6 -1.7 1.6 0.6 0.9 0.1
Pain all over the body in last month 2.1 2.3 6.4 -2.0 0.0 -1.2 -1.6 -2.5 -1.4 0.4 -1.4
Diabetes (self-reported) 0.4 0.6 2.0 -1.4 0.0 0.6 0.9 -0.8 -0.3 -0.7 -0.1
Hayfever/allergic rhinitis (self-reported) 1.4 1.8 4.5 1.6 0.0 1.1 2.1 0.9 1.6 -0.2 1.7
Medication: Ramipril 0.8 1.0 3.8 -0.0 0.0 1.9 -0.1 0.6 1.1 1.4 0.7
Medication: Simvastatin 0.7 1.0 3.4 -1.7 0.0 0.3 -0.3 -1.8 -0.9 0.4 -0.9
Fluid intelligence score 0.4 0.8 2.2 1.5 0.0 -1.2 1.1 0.1 0.6 0.0 1.0
Illnesses of siblings 0.3 0.4 1.6 0.5 0.0 -1.3 -0.1 -0.2 -0.3 -1.1 -0.4
Neuroticism score 0.7 1.5 3.4 -1.2 0.0 -1.8 -1.4 -1.4 -1.2 -0.9 -0.9
Weight 0.1 0.4 2.0 0.6 0.0 -1.4 0.3 -0.4 0.3 -0.1 0.3
Impedance of arm (right) 0.7 3.3 7.5 0.2 0.0 2.3 1.2 0.6 2.4 2.7 2.5
Arm fat percentage (right) 0.1 0.5 1.1 -1.1 0.0 -0.6 0.9 -0.0 1.0 0.7 0.8
Trunk fat-free mass 0.3 1.6 8.4 2.9 0.0 -1.9 0.1 -0.2 0.2 -0.6 0.5
Hip circumference 0.1 0.5 3.8 0.5 0.0 -1.9 0.2 -0.4 0.4 -0.1 0.2
Time employed in main current job 1.2 1.4 3.8 1.6 0.0 -0.3 0.9 2.0 1.2 0.4 1.5
Alcohol intake versus 10 years previously 2.0 3.0 5.8 -1.8 0.0 -1.2 -1.6 -1.6 -2.0 -2.4 -2.0
Father’s age at death 2.7 3.6 10.0 1.7 0.0 -1.2 2.1 3.2 2.2 0.5 2.2
Worrier / anxious feelings 0.7 1.4 2.8 -1.5 0.0 -0.6 -1.3 -1.7 -1.4 -0.0 -1.3
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.6 1.1 0.7 0.0 0.2 0.9 -0.6 1.1 0.7 1.0
Falls in the last year 0.9 1.3 2.4 -1.1 0.0 -0.6 -0.8 -1.3 -1.5 -1.2 -1.5
Hair/balding pattern: Pattern 3 0.7 1.1 5.8 -0.3 0.0 -0.0 -0.9 -0.4 -1.0 -2.4 -0.9
Number of live births 1.0 1.4 7.0 -0.2 0.0 2.6 0.2 1.8 0.7 0.5 0.2
Forced expiratory volume in 1-second (FEV1) 0.3 1.0 3.5 1.1 0.0 -1.9 -0.8 -0.7 -1.1 -0.1 -0.9
Pulse rate 0.4 0.6 3.3 -0.3 0.0 0.1 1.8 0.4 0.7 0.2 1.0
Happiness 1.1 1.3 4.0 -0.6 0.0 -2.0 -1.7 -0.7 -1.2 0.0 -1.2
Noisy workplace 0.1 0.1 0.8 0.0 0.0 0.9 -0.3 -0.1 -0.4 -0.0 -0.3
Qualifications: A levels/AS levels or equivalent 0.1 0.3 1.0 1.0 0.0 -0.9 0.3 0.2 0.2 -0.1 0.4
Serious illness, injury or assault of a close relative in last 2 years 1.3 1.5 4.2 2.1 0.0 -0.8 1.6 0.6 1.2 1.1 1.4
Mouth/teeth dental problems: Dentures 0.4 0.7 3.1 -0.5 0.0 1.8 1.3 0.4 0.6 -0.2 0.5
Asthma 0.9 1.8 4.5 -2.1 0.0 0.2 1.4 -1.9 -1.3 -1.5 -0.7
Medication: Ibuprofen (e.g. Nurofen) 2.4 3.1 7.0 -1.9 0.0 -1.2 -2.4 -0.3 -2.6 -1.3 -2.3
Medication: Cholesterol lowering 1.4 2.2 6.3 0.3 0.0 2.5 1.7 1.0 1.9 0.4 1.8
Depression (self-reported) 1.6 1.9 3.4 -1.3 0.0 -1.6 -1.7 -1.4 -1.9 0.5 -1.6
Medication: Lansoprazole 1.4 1.6 3.4 -1.8 0.0 -1.6 -1.9 -0.6 -1.1 -0.9 -1.2
Prospective memory result 0.4 0.4 0.8 -0.9 0.0 -0.2 0.4 0.7 -0.8 -0.6 -0.9
Lung cancer (father) 0.6 0.7 2.6 -0.1 0.0 -1.6 -0.3 -0.4 -0.4 -1.4 -0.3
Illnesses of mother 0.4 0.5 1.5 0.4 0.0 -0.1 -0.0 1.2 -0.8 -1.0 -0.8
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.8 4.3 2.1 0.0 -1.3 -0.4 -0.2 -0.3 0.0 -0.0
Pulse wave Arterial Stiffness index 0.5 0.6 2.4 -1.2 0.0 0.7 0.4 -1.6 0.4 0.5 0.3
Impedance of arm (left) 0.7 3.2 7.4 0.4 0.0 2.7 0.5 0.8 2.3 2.5 2.3
Arm fat mass (right) 0.1 0.3 1.1 -0.4 0.0 -1.1 0.5 -0.3 0.5 0.2 0.3
Trunk predicted mass 0.3 1.6 8.6 2.9 0.0 -2.0 0.1 -0.2 0.2 -0.5 0.5
Standing height 0.3 3.3 17.6 4.2 0.0 0.5 0.2 0.2 1.7 0.7 2.2
Length of working week for main job 0.4 0.5 2.3 0.9 0.0 -0.4 -0.4 0.7 -0.2 -1.5 -0.1
Exposure to tobacco smoke at home 0.3 0.4 1.4 0.4 0.0 0.2 -0.3 1.1 0.2 1.2 0.1
Breastfed as a baby 0.7 0.8 5.8 0.1 0.0 -2.4 -0.0 0.4 0.2 -0.7 0.2
Tense / ‘highly strung’ 0.4 0.6 1.6 -1.3 0.0 -0.6 -1.2 0.6 -0.6 0.1 -0.8
Seen doctor (GP) for nerves, anxiety, tension or depression 1.1 1.8 3.6 -1.9 0.0 -1.2 -1.2 -0.4 -1.8 -1.0 -1.8
Hair/balding pattern: Pattern 4 0.5 1.3 3.5 1.2 0.0 1.0 0.7 0.8 1.7 0.5 1.9
Birth weight of first child 0.4 0.8 3.3 1.1 0.0 0.2 1.8 0.6 1.0 -0.5 0.7
Peak expiratory flow (PEF) 0.8 2.0 8.0 -0.3 0.0 -2.8 0.3 -1.2 -1.4 -1.6 -1.3
Pulse wave reflection index 0.8 1.0 4.5 -1.6 0.0 -0.0 0.4 -2.1 -0.7 0.5 -0.6
Ever highly irritable/argumentative for 2 days 0.5 0.6 1.8 -0.0 0.0 -1.1 -0.9 -0.1 -0.7 1.3 -0.6
Loud music exposure frequency 2.0 2.2 5.6 2.4 0.0 1.0 1.2 1.8 1.8 0.3 1.6
Qualifications: O levels/GCSEs or equivalent 0.5 0.8 2.3 0.9 0.0 -0.2 1.3 0.4 1.0 1.5 0.9
Mouth/teeth dental problems: Bleeding gums 2.4 3.1 6.0 2.3 0.0 -0.1 2.1 0.9 2.4 1.6 2.4
Blood clot in the leg (DVT) 1.0 1.3 2.2 -1.1 0.0 -1.5 -0.9 -0.1 -1.5 -1.2 -1.5
Medication: Paracetamol 0.7 1.1 5.3 -2.3 0.0 -0.2 -1.1 -0.2 -1.1 0.3 -1.1
Headache pain in last month 0.3 0.5 1.6 0.5 0.0 0.0 -0.2 1.0 0.7 1.3 0.8
Medication for cholesterol, blood pressure or diabetes 1.5 2.4 15.3 0.1 0.0 -3.9 -0.8 0.3 -1.3 -0.4 -1.2
Glaucoma (self-reported) 1.8 2.1 4.0 1.4 0.0 1.4 1.4 1.6 1.9 0.9 2.0
Gout (self-reported) 0.3 0.5 1.9 -0.3 0.0 1.2 -1.4 -0.3 -0.1 0.4 -0.4
Hypothyroidism/myxoedema (self-reported) 0.5 1.0 3.0 -1.4 0.0 -1.0 -0.1 -1.7 -1.0 0.3 -1.0
Medication: Amlodipine 1.6 2.3 8.8 -0.9 0.0 3.0 1.3 -1.1 0.9 2.2 0.5
Medication: Ventolin 100micrograms inhaler 0.5 0.6 1.6 -0.8 0.0 0.1 0.1 -1.3 -1.0 -1.2 -0.6
Birth weight 0.7 1.4 9.1 -0.4 0.0 -0.9 -0.5 0.0 -0.8 -3.0 -0.8
Chronic bronchitis/emphysema (mother) 1.5 1.7 3.8 2.0 0.0 1.5 1.4 0.3 1.7 -0.0 1.7
High blood pressure (siblings) 0.7 1.0 2.5 -0.1 0.0 1.0 1.2 0.6 0.9 1.6 1.2
Forced vital capacity (FVC), Best measure 0.2 0.7 4.4 2.1 0.0 -0.6 -0.6 -0.8 -0.1 0.3 0.0
Body fat percentage 0.2 0.8 1.9 -1.0 0.0 0.5 0.9 0.1 1.4 1.0 1.2
Leg fat percentage (right) 0.2 0.6 2.4 -1.5 0.0 0.8 0.5 -0.7 0.8 0.4 0.5
Arm fat-free mass (right) 0.2 1.2 4.8 2.2 0.0 -1.8 -0.5 0.1 -0.3 -0.9 -0.2
Exposure to tobacco smoke outside home 0.3 0.5 1.0 0.4 0.0 -1.0 -0.7 1.0 0.4 1.0 0.4
Comparative body size at age 10 0.8 2.2 5.1 -1.1 0.0 -2.3 -0.4 -1.7 -1.9 -1.0 -1.9
Number of full brothers 0.4 0.5 1.8 -0.1 0.0 -0.7 1.0 1.4 0.7 0.3 0.5
Worry too long after embarrassment 0.1 0.2 0.7 -0.1 0.0 -0.3 -0.8 -0.0 -0.4 -0.7 -0.0
Seen a psychiatrist for nerves, anxiety, tension or depression 0.8 1.0 4.3 -0.7 0.0 -1.8 -0.2 2.1 -0.3 -0.4 -0.2
Wheeze or whistling in the chest in last year 0.4 0.8 4.2 -2.0 0.0 -0.7 -0.2 -0.4 -0.9 -0.4 -0.7
Number of children fathered 0.3 0.4 1.0 0.1 0.0 1.0 -0.2 -0.9 -0.6 -0.4 -0.7
Reason for reducing amount of alcohol drunk: Health precaution 0.3 0.3 1.7 -0.0 0.0 -0.8 0.2 -0.2 -0.0 -1.3 -0.1
Age at first live birth 0.2 0.3 0.9 0.1 0.0 -0.2 0.8 0.9 0.5 -0.6 0.5
Pulse wave peak to peak time 0.7 0.8 2.6 1.5 0.0 -0.9 -0.5 1.6 -0.2 -0.6 -0.1
Health satisfaction 0.3 0.4 2.2 0.1 0.0 -0.1 -0.9 -0.1 0.1 1.5 0.6
Shortness of breath walking on level ground 0.2 0.2 0.8 0.2 0.0 0.1 -0.4 0.7 0.9 0.0 0.7
Qualifications: College or University degree 0.6 1.9 6.6 2.6 0.0 -1.1 1.5 1.5 0.7 0.9 1.2
Eye problems/disorders: None of the above 1.6 1.9 8.5 -1.6 0.0 -0.1 -0.7 -2.9 -1.1 0.6 -1.5
Mouth/teeth dental problems: Loose teeth 0.4 0.4 1.4 -1.2 0.0 0.4 -0.4 -0.7 -0.6 -0.5 -0.8
Emphysema/chronic bronchitis 0.3 0.3 1.3 -0.5 0.0 -1.1 -0.1 0.5 0.2 -0.8 0.2
Medication for pain relief, constipation, heartburn 0.5 0.8 3.5 1.9 0.0 -0.2 0.3 1.1 0.8 0.3 0.8
Neck or shoulder pain in last month 0.8 1.2 3.5 -1.5 0.0 -0.2 -1.9 -0.7 -1.2 -0.9 -1.0
Medication: Blood pressure 1.4 2.5 15.7 0.4 0.0 4.0 0.6 -0.3 1.2 0.7 1.1
Angina (self-reported) 0.5 0.7 2.7 -1.1 0.0 1.6 -0.5 -0.4 0.4 0.9 0.3
Migraine (self-reported) 0.2 0.3 0.6 -0.3 0.0 -0.7 0.8 -0.4 0.6 -0.6 0.4
Medication: Ibuprofen 0.9 1.1 2.6 -1.1 0.0 -0.8 -1.6 0.8 -1.1 -1.2 -0.9
Medication: Allopurinol 0.3 0.4 1.3 -0.2 0.0 -0.0 -1.2 -0.8 -0.2 -0.8 -0.3
Medication: Omeprazole 0.5 0.6 2.7 -1.6 0.0 -0.4 -0.7 0.1 -0.6 -0.8 -0.9
Medication: Seretide 50 evohaler 2.1 2.4 4.5 -1.8 0.0 0.5 -2.0 -2.1 -2.1 0.2 -1.8
Mean time to correctly identify matches 1.6 3.0 6.2 1.0 0.0 2.5 1.8 1.9 1.9 1.8 1.9
Heart disease (mother) 0.5 0.6 2.2 -1.0 0.0 -0.0 -0.9 -1.5 -0.3 0.4 -0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.7 0.8 2.4 -0.4 0.0 -0.3 -1.2 -0.1 -1.5 -0.7 -1.4
Whole body fat mass 0.1 0.3 1.0 -0.3 0.0 -0.1 0.7 -0.2 1.0 0.5 0.9
Leg fat mass (right) 0.0 0.2 0.4 -0.3 0.0 -0.4 0.6 -0.3 0.7 0.2 0.6
Arm predicted mass (right) 0.2 0.9 3.7 1.9 0.0 -1.7 -0.3 -0.3 -0.4 -0.7 -0.3
Pulse rate, automated reading 0.7 2.2 10.7 -0.4 0.0 -0.3 3.3 -0.9 1.4 1.0 1.7
Alcohol intake frequency. 1.3 3.0 6.5 -2.5 0.0 -1.2 -2.3 -1.6 -2.0 -0.3 -2.2
Comparative height size at age 10 0.3 1.5 6.7 2.6 0.0 0.9 -1.3 0.2 1.0 0.5 1.1
Number of full sisters 0.3 0.4 1.3 -1.1 0.0 -0.0 -0.8 0.4 -0.8 -0.1 -0.7
Suffer from ‘nerves’ 1.1 1.7 4.0 -1.1 0.0 -1.7 -1.3 -1.1 -1.1 -2.0 -1.3
Overall health rating 0.3 0.7 5.0 -2.2 0.0 -0.1 -0.1 -0.6 -0.4 -0.1 -0.2
Chest pain or discomfort 2.8 4.1 9.7 -2.4 0.0 -2.0 -1.6 -3.1 -2.3 -1.1 -2.1
Had major operations 0.4 0.4 2.1 0.8 0.0 -0.2 -0.3 0.8 -0.0 -1.5 0.1
Age at last live birth 0.2 0.2 0.9 -0.6 0.0 1.0 0.7 0.0 0.3 0.0 0.2
Family relationship satisfaction 0.7 0.9 4.3 1.0 0.0 -2.1 -0.1 -0.0 0.4 1.1 0.7
Leg pain on walking 0.7 0.9 4.2 -1.0 0.0 -0.2 -0.9 0.7 -0.7 2.0 -0.6
Qualifications: NVQ or HND or HNC or equivalent 2.0 2.4 4.3 -2.1 0.0 -0.2 -1.8 -1.8 -1.6 -1.3 -2.0
Commuting to job workplace: Car/motor vehicle 1.9 2.2 6.1 -2.1 0.0 0.2 -2.5 -1.3 -1.3 -0.9 -1.6
Illness, injury, bereavement, stress in last 2 years 1.9 2.3 7.7 1.2 0.0 1.5 0.6 2.8 1.9 0.4 1.7
Medication: Aspirin 0.8 1.1 3.1 0.8 0.0 1.7 1.3 -0.9 1.3 -0.0 1.0
Supplements: Vitamin C 1.2 1.4 3.0 1.3 0.0 0.1 1.7 0.7 1.7 0.6 1.7
Knee pain experienced in last month 0.0 0.1 0.3 0.5 0.0 0.5 -0.3 0.0 -0.1 0.0 0.1
Hypertension (Self-reported) 2.2 6.1 27.4 -1.2 0.0 5.2 1.4 0.8 1.9 3.2 1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.6 1.9 -1.4 0.0 0.1 -1.1 -0.6 -0.2 -1.0 -0.6
Illnesses of father: Heart disease 1.0 1.3 6.6 -1.3 0.0 0.3 -0.1 -2.6 -0.5 -1.4 -0.5
Illnesses of siblings: Diabetes 0.4 0.5 1.4 -1.0 0.0 0.6 -0.8 -0.4 -0.5 1.2 -0.6
Smoking status: Previous 0.6 0.9 5.2 -0.5 0.0 2.3 0.8 0.4 0.5 -0.5 0.6
Forced expiratory volume in 1-second (FEV1), predicted 0.5 0.9 4.5 2.1 0.0 -1.3 -0.3 -0.8 0.2 0.5 0.7
Whole body fat-free mass 0.3 1.6 6.0 2.4 0.0 -2.5 -0.3 -0.2 -0.2 -0.8 0.0
Leg fat-free mass (right) 0.3 1.8 9.4 1.5 0.0 -3.1 -0.9 -0.1 -0.8 -0.9 -0.7
Arm fat percentage (left) 0.1 0.4 1.4 -1.2 0.0 -0.6 0.5 -0.0 0.7 0.6 0.4
Average weekly red wine intake 0.9 1.4 4.5 1.9 0.0 -2.1 1.3 0.9 0.3 -0.2 0.8
Handedness (chirality/laterality): Left-handed 0.9 1.1 2.3 1.0 0.0 1.5 1.1 0.9 1.2 -0.7 1.1
Mood swings 0.2 0.5 1.9 -1.4 0.0 -0.6 -1.0 0.1 -0.4 -0.1 -0.4
Loneliness, isolation 0.7 1.0 3.0 -1.3 0.0 -1.7 0.6 -1.3 -0.6 -0.7 -0.4
Long-standing illness, disability or infirmity 0.3 0.4 1.0 -0.6 0.0 1.0 -0.0 1.0 -0.2 0.9 0.1
Ever had bowel cancer screening 0.7 0.8 3.2 0.6 0.0 0.4 1.8 0.3 1.1 0.4 1.0
Diabetes diagnosed by doctor 0.3 0.5 2.3 -1.5 0.0 0.9 0.0 -0.5 -0.5 -0.1 -0.4
Ever had stillbirth, spontaneous miscarriage or termination 0.5 0.5 2.0 0.5 0.0 1.4 1.2 -0.3 0.4 0.0 0.4
Friendships satisfaction 0.5 0.6 1.7 -0.6 0.0 -1.3 -1.1 -1.2 -0.5 -0.0 -0.2
Qualifications: nursing, teaching 0.6 0.9 4.0 0.4 0.0 -0.2 0.7 1.0 0.6 2.0 1.0
Commuting to job workplace: Walk 0.1 0.1 0.3 0.2 0.0 -0.4 0.4 0.3 -0.6 -0.2 -0.4
Eye problems/disorders: Cataract 0.8 1.0 5.7 0.5 0.0 -0.8 0.2 2.4 0.1 -1.0 0.3
Mouth/teeth dental problems: Mouth ulcers 0.5 0.8 2.3 0.0 0.0 -1.3 -0.9 1.5 -0.6 -0.9 -0.4
Medication for cholesterol 0.9 1.4 4.2 2.0 0.0 -2.0 0.1 0.8 -0.0 -1.7 0.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.1 1.3 3.3 1.8 0.0 1.7 0.9 -0.1 1.1 0.4 1.4
Back pain experienced in last month 0.5 0.8 2.4 -1.0 0.0 -1.5 0.1 -1.0 -0.9 0.7 -0.7
Mineral and other dietary supplements 0.4 0.6 2.3 -0.2 0.0 1.1 -0.1 0.7 0.4 1.5 0.4
Breast cancer (self-reported) 1.1 1.3 5.7 1.3 0.0 -2.4 0.5 0.9 0.3 -1.2 0.6
Asthma (self-reported) 1.2 2.5 5.6 -2.4 0.0 0.5 1.4 -2.3 -1.5 -1.8 -0.9
Osteoporosis (self-reported) 0.3 0.4 1.4 -0.7 0.0 0.4 -0.4 0.4 -0.6 -1.2 -0.8
Osteoarthritis (self-reported) 0.7 0.9 1.9 -0.5 0.0 1.4 -1.3 -1.1 -0.8 -0.9 -0.8
Medication: Aspirin 0.9 1.2 2.7 0.8 0.0 1.6 1.4 -0.4 1.5 0.5 1.2
Medication: Gliclazide 1.4 1.6 3.3 1.8 0.0 1.8 1.0 -0.0 1.5 1.1 1.4
Illnesses of father: None of the above (group 1) 0.8 1.0 2.4 0.3 0.0 -1.6 -0.4 0.1 -1.2 -1.5 -1.2
Smoking status: Current 0.3 0.5 1.3 0.3 0.0 0.2 1.1 -0.1 0.8 1.1 0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.4 0.8 2.4 1.4 0.0 0.3 -0.3 1.5 0.6 1.0 0.8
Whole body water mass 0.3 1.6 6.2 2.3 0.0 -2.5 -0.4 -0.3 -0.3 -0.8 -0.1
Leg predicted mass (right) 0.3 1.8 9.4 1.4 0.0 -3.1 -0.9 -0.1 -0.8 -0.9 -0.7
Arm fat mass (left) 0.0 0.2 0.4 -0.3 0.0 -0.6 0.6 -0.0 0.6 0.4 0.4
Number of self-reported non-cancer illnesses 1.2 2.1 12.3 -1.8 0.0 3.5 0.2 -0.8 -0.5 -0.3 -0.1
Average weekly champagne plus white wine intake 0.1 0.1 0.5 -0.3 0.0 -0.7 0.3 0.3 -0.1 0.0 -0.1
Miserableness 0.2 0.4 0.8 0.9 0.0 -0.5 0.4 0.2 0.9 0.4 0.8
Guilty feelings 0.1 0.1 0.2 -0.5 0.0 0.3 0.1 -0.3 -0.4 0.3 -0.1
Wears glasses or contact lenses 1.4 1.6 3.5 0.6 0.0 1.9 1.6 1.0 1.7 -0.8 1.3
Ever taken oral contraceptive pill 0.5 0.6 1.5 1.2 0.0 -0.5 1.2 0.7 0.4 0.7 0.7
Hearing aid user 0.5 0.6 1.3 -0.6 0.0 0.9 -0.3 -0.7 -1.1 0.9 -0.9
Mother’s age at death 3.7 4.6 12.6 2.6 0.0 0.6 3.5 0.6 2.8 0.8 3.0
Financial situation satisfaction 0.6 0.7 3.2 -0.6 0.0 -1.4 -0.3 -0.4 -0.4 1.8 -0.2
Tinnitus: Yes, now most or all of the time 0.3 0.3 1.0 -0.3 0.0 1.0 0.2 0.8 0.1 0.8 0.1
Commuting to job workplace: Public transport 0.3 0.4 1.5 -0.1 0.0 -0.6 1.2 -0.7 0.1 0.7 0.2
Eye problems/disorders: Glaucoma 1.6 1.9 4.2 1.3 0.0 0.9 1.3 1.5 2.0 0.6 2.0
Medication: Blood pressure 1.5 2.8 8.9 -2.5 0.0 3.0 -0.2 -0.2 0.4 2.7 0.1
Pain type(s) experienced in last month: Hip pain 1.0 1.2 2.8 -1.7 0.0 0.9 -0.0 -1.6 -1.3 0.5 -1.2
Supplements: Fish oil (including cod liver oil) 0.5 0.7 3.3 -0.6 0.0 -1.0 -0.0 -0.9 -0.4 -1.8 -0.4
High cholesterol (Self-reported) 0.4 0.7 2.0 -1.4 0.0 0.9 -0.3 -0.7 -0.5 1.2 -0.6
Medication: Bendroflumethiazide 1.1 1.7 7.6 -0.0 0.0 2.8 1.4 0.4 0.8 1.5 0.8
Medication: Paracetamol 0.6 0.9 4.5 -2.1 0.0 -0.4 -1.0 0.4 -0.9 0.1 -0.8
Medication: Lisinopril 1.0 1.3 3.2 -1.8 0.0 1.3 -0.6 -0.3 -0.9 -1.7 -1.1
Medication: Atorvastatin 1.2 1.4 3.3 0.4 0.0 1.6 1.4 0.3 1.8 1.0 1.5
Illnesses of father: High blood pressure 0.5 0.6 3.0 -0.5 0.0 1.7 -1.0 -0.3 -0.1 0.7 0.0
Alcohol drinker status: Never 0.2 0.2 0.7 -0.3 0.0 -0.1 0.2 -0.2 -0.7 -0.8 -0.6
Ever smoked 0.0 0.1 0.3 -0.1 0.0 0.6 0.3 0.3 -0.1 -0.1 -0.1
Basal metabolic rate 0.2 1.2 5.4 1.9 0.0 -2.3 -0.3 -0.3 -0.2 -0.5 -0.0
Leg fat percentage (left) 0.1 0.5 3.2 -1.8 0.0 0.5 0.4 -0.2 0.6 0.4 0.3
Arm fat-free mass (left) 0.2 0.9 3.4 1.8 0.0 -1.9 0.0 -0.4 -0.2 -0.6 0.0
Number of operations (self-reported) 0.3 0.4 1.0 1.0 0.0 0.0 0.3 0.9 0.5 1.0 0.7
Average weekly beer plus cider intake 0.1 0.1 0.6 -0.1 0.0 0.3 -0.1 0.8 0.1 -0.3 -0.1
Irritability 0.3 0.5 2.2 -0.5 0.0 -1.5 -0.7 -0.0 -0.4 0.9 -0.1
Risk taking 0.9 1.3 4.2 1.1 0.0 0.2 0.2 1.8 0.9 2.0 1.0
Ever had prostate specific antigen (PSA) test 0.3 0.3 1.0 0.4 0.0 -0.7 1.0 0.9 0.3 -0.0 0.4
Fractured/broken bones in last 5 years 1.4 1.8 4.5 -0.7 0.0 -0.7 -1.2 -1.8 -1.9 -0.6 -2.1
Age started oral contraceptive pill 0.3 0.4 1.2 -0.3 0.0 -0.4 -0.1 0.1 -0.9 -0.9 -1.1
Diastolic blood pressure, automated reading 1.0 3.2 10.3 -1.7 0.0 3.2 1.6 0.5 1.5 2.5 1.2
Ever depressed for a whole week 0.9 1.1 2.8 -0.5 0.0 -1.4 -1.7 -0.7 -1.4 -0.7 -1.0
Unable to work because of sickness or disability 0.5 0.7 3.2 0.2 0.0 1.0 0.5 1.8 0.5 0.8 0.4
Commuting to job workplace: Cycle 1.3 1.6 3.7 -1.0 0.0 -0.9 -1.3 -0.9 -1.6 -1.4 -1.9
Myopia 0.4 0.6 2.0 -0.7 0.0 -1.4 0.6 -0.3 -1.0 -0.6 -0.9
Vascular/heart problems diagnosed by doctor 1.9 5.2 26.2 1.5 0.0 -5.1 -0.4 -0.7 -1.6 -2.8 -1.4
Cholesterol lowering medication 1.3 1.8 6.8 -1.9 0.0 0.3 -0.4 -1.9 -0.5 2.6 -0.6
Medication: Omeprazole (e.g. Zanprol) 1.4 1.7 4.5 -2.1 0.0 -0.6 -1.2 -1.1 -1.3 -1.2 -1.7
Pain experienced in last month 0.2 0.3 1.3 0.9 0.0 0.5 0.5 -0.0 -0.0 -1.1 -0.0
Supplements: Calcium 0.2 0.2 0.9 0.5 0.0 -0.3 1.0 -0.7 -0.2 -0.1 -0.2
Basal cell carcinoma (self-reported) 0.5 0.6 2.1 0.2 0.0 -0.8 0.4 1.4 0.8 0.6 0.8
Heart attack/myocardial infarction (self-reported) 0.6 0.7 2.1 -0.4 0.0 1.5 0.0 0.8 1.4 0.1 0.9
Deep venous thrombosis (DVT) (self-reported) 0.7 0.9 1.5 -1.1 0.0 -1.1 -0.9 -0.3 -1.2 -1.1 -1.2
Heart disease (siblings) 1.4 1.7 4.8 -1.9 0.0 0.1 -2.2 -0.2 -1.3 -0.8 -1.6
Alcohol drinker status: Previous 0.6 0.7 2.4 0.7 0.0 0.4 0.4 1.6 1.1 0.3 0.9
Pack years of smoking 0.7 1.0 1.8 -1.1 0.0 -1.4 -1.1 -0.8 -1.1 -0.7 -1.3
Impedance of whole body 0.8 4.1 12.4 0.1 0.0 3.5 0.8 0.7 2.3 2.9 2.4
Leg fat mass (left) 0.0 0.2 0.3 -0.6 0.0 -0.6 0.5 -0.2 0.4 0.3 0.4
Arm predicted mass (left) 0.2 1.1 4.6 1.5 0.0 -2.1 -0.2 -0.6 -0.6 -1.1 -0.3