Hub : Genes

EIF4E3

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1770 0.0390 6.1e-06 0.069 0.060 0.114 0.120 0.121 8.5e-09 8.9e-08 9.5e-14 1.9e-14 1.7e-14
2 GTEx Breast Mammary Tissue 0.2170 0.0690 3.2e-03 -0.006 NA 0.006 NA 0.000 9.6e-01 NA 1.6e-01 NA 3.1e-01
3 GTEx Breast Mammary Tissue (Male) 0.2150 0.1659 1.5e-01 -0.007 NA -0.013 NA -0.012 4.9e-01 NA 9.5e-01 NA 7.8e-01
4 GTEx Breast Mammary Tissue (Female) 0.2576 0.1018 1.9e-02 0.024 NA -0.009 NA 0.025 6.3e-02 NA 7.9e-01 NA 6.1e-02
5 NTR Blood 0.1251 0.0260 4.1e-08 0.026 0.031 0.039 0.036 0.030 6.2e-09 3.1e-10 1.7e-12 1.2e-11 3.8e-10
6 YFS Blood 0.3434 0.0373 0.0e+00 0.100 0.191 0.192 NA 0.152 7.9e-31 2.1e-60 1.1e-60 NA 3.4e-47
7 TCGA Breast Invasive Carcinoma 0.0541 0.0201 1.5e-04 0.004 0.020 0.005 NA 0.000 4.6e-02 3.6e-05 2.4e-02 NA 3.5e-01
8 TCGA Prostate Adenocarcinoma 0.0540 0.0247 6.9e-03 0.039 0.011 0.021 NA 0.020 6.1e-05 2.2e-02 2.3e-03 NA 3.4e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.2 0.3 1.0 -0.9 0.3 -0.3 0.3 0.2 -0.1 -1.0 -0.6
Bipolar Disorder or Schizophrenia 0.4 0.9 2.7 0.1 0.1 1.0 0.6 -0.2 -0.6 -1.6 -1.5
Depressed Affect (Nagel 2018) 0.9 1.8 11.3 -1.0 -0.5 0.6 0.2 0.6 0.0 1.3 3.4
Depression (Nagel 2018) 1.4 2.1 5.9 1.5 -0.2 1.2 -1.2 0.0 1.7 1.8 2.4
Intelligence (Savage-Jansen 2018) 0.8 2.6 15.4 -0.3 -0.2 -3.9 -1.1 1.4 -0.2 0.1 1.4
Neuroticism (Nagel 2018) 0.6 1.4 4.3 -0.1 1.1 1.5 0.9 0.9 1.0 0.7 2.1
Schizophrenia (2018) 0.5 1.0 2.3 0.8 -0.1 1.5 0.6 -0.7 -0.6 -1.3 -1.4
Schizophrenia vs Biploar Disorder 0.6 0.8 2.1 1.5 0.5 -0.3 1.0 -0.7 -1.1 1.2 -0.1
Worry (Nagel 2018) 0.9 1.9 5.7 0.4 2.4 0.7 1.9 0.9 1.4 -1.4 -0.5
Alzheimer’s Disease (in mother) 1.5 1.8 3.1 1.8 1.6 -1.1 1.1 0.6 0.9 1.4 1.8
Alzheimer’s Disease (in father) 0.7 0.7 2.1 -1.4 -0.9 -0.4 -0.2 0.3 -1.2 0.7 0.9
Alzheimer’s Disease (including proxy) 0.8 1.2 4.8 0.1 0.4 -1.0 0.5 1.4 0.5 1.1 2.2
Crohns Disease (2017) 0.7 1.5 4.2 0.4 -0.5 -0.7 -1.1 0.7 1.3 1.9 2.0
Irritable Bowel Disease (IBD) 0.8 1.9 4.7 1.8 -0.1 0.4 -1.6 0.6 0.9 1.8 2.2
Ulcerative Colitis (UC) 0.9 1.8 5.9 2.4 0.7 1.6 -1.6 0.5 0.4 0.9 1.1
Major Depression (MDD) 1.3 1.6 5.1 -0.7 -1.1 0.6 -1.3 0.5 1.3 1.5 2.3
Reaction Time 0.8 1.6 5.7 -1.7 -0.7 0.3 0.7 -0.2 -1.6 -0.5 -2.4
Verbal and Numeric Reasoning (VNR) 0.7 1.8 8.8 0.6 0.2 -3.0 -1.7 0.3 -0.8 0.3 1.0
Breast Cancer 0.5 1.3 4.3 -0.1 -0.6 -2.0 0.9 -2.1 -0.2 -0.5 -0.5
Ovarian Cancer 0.6 0.8 2.9 -1.5 -0.1 0.1 -0.1 0.8 0.6 1.7 0.4
Prostate Cancer 0.9 1.2 3.8 1.1 -0.9 1.3 0.1 1.0 0.9 -0.7 1.9
Age at First Birth 0.5 0.8 2.9 0.9 1.0 -0.5 1.7 -0.6 -0.9 0.0 0.5
Bipolar Disorder (2011) 0.4 0.4 1.2 -0.0 0.5 1.1 0.7 -0.9 -0.4 0.0 0.0
Body Mass Index (BMI) (2010) 1.0 1.4 3.1 -0.7 0.2 -0.5 -0.1 -1.5 -1.7 1.8 1.5
Coronary Artery Disease (CAD) 2.7 3.2 10.0 -0.6 2.9 1.8 0.8 -3.2 -1.5 0.6 -0.9
Crohns Disease (2012) 0.4 0.7 1.3 0.7 0.7 -0.5 -0.7 0.9 1.1 0.7 1.1
Mean Putamen Volume 2.2 2.5 6.3 1.4 1.4 0.4 1.3 -1.2 0.5 2.4 2.5
Fasting Glucose 0.7 0.9 2.8 -0.6 -0.8 -1.7 0.5 1.4 -0.5 0.4 -0.7
HbA1C 0.3 0.3 0.9 -0.4 1.0 -0.2 -0.8 0.7 -0.1 -0.1 -0.5
HDL Cholesterol 1.4 2.3 7.3 1.6 -0.4 -0.7 0.5 2.7 2.3 0.6 1.6
LDL Cholesterol 0.3 0.5 2.6 1.6 -0.3 -0.1 -0.3 0.2 0.2 1.1 0.5
Lupus 0.6 0.9 2.0 -1.0 0.3 0.0 1.4 -1.0 -1.0 0.7 1.4
Neuroticism (2016) 1.5 2.2 9.9 -0.3 -0.2 1.4 -1.2 -0.2 1.0 1.8 3.1
Primary Biliary Cirrhosis 0.2 0.2 0.5 0.5 0.1 0.3 0.5 -0.6 -0.7 0.5 0.5
Rheumatoid Arthritis 1.9 2.7 10.4 0.7 -1.6 1.2 -3.2 0.1 1.9 1.6 0.1
Schizophrenia (2014) 0.9 1.9 3.5 1.6 1.1 1.2 1.9 -1.0 -1.3 -1.0 -1.8
Triglycerides 1.0 1.6 3.4 0.2 0.1 1.8 -1.1 -1.4 -1.9 1.6 0.7
Type 2 Diabetes (T2D) (2012) 2.2 2.5 10.5 -0.2 1.3 0.7 0.5 -3.2 -2.7 -0.3 0.3
Ulcerative Colitis 1.0 1.4 7.3 2.7 -0.2 0.9 -1.1 -0.1 0.1 -0.3 1.3
Blood Eosinophil Count 0.6 5.0 12.8 3.6 -0.8 1.9 -0.5 3.4 3.2 -0.3 -0.7
Blood Platelet Count 0.1 1.7 4.2 2.0 -1.4 -0.1 -1.6 0.2 1.3 0.4 1.7
Blood Red Count 0.6 6.1 17.6 -2.1 1.2 2.3 -3.6 -4.2 -1.4 -1.3 -1.8
Blood White Count 0.2 1.5 3.4 1.7 -1.7 -0.6 -0.7 1.4 1.8 0.2 -0.1
Heel T-Score 0.2 1.6 4.0 -1.9 -0.3 0.1 -0.5 -1.5 -2.0 0.4 1.6
BMI 0.5 2.7 10.0 1.6 -2.1 0.8 -3.2 -1.3 0.4 1.0 1.0
Height 0.1 1.9 9.7 -0.1 -3.1 -1.1 -0.3 -0.9 -1.7 -0.5 0.6
Waist Hip Ratio (WHR) 0.1 0.5 1.7 -0.1 -0.2 -1.3 0.0 0.2 0.6 -1.0 -1.0
Systolic Blood Pressure 0.3 1.4 4.5 -0.2 -1.0 0.3 -1.5 1.5 -0.0 -1.3 -2.1
Smoking Status 0.9 2.1 8.4 -0.1 -1.7 -0.3 -1.4 1.7 0.8 2.9 0.5
Allergy or Eczema 0.9 2.3 7.1 -0.7 1.4 0.1 1.7 -0.6 -0.1 2.7 2.3
Cardiovascular Disease 0.3 1.0 2.7 1.1 -1.7 0.0 -1.5 -0.8 1.0 -0.7 0.1
Hypothyroidism (self reported) 0.4 0.9 2.6 0.5 1.5 1.1 -0.2 -0.0 0.9 -1.6 -0.5
Respiratory disease 0.8 1.9 5.3 1.0 -2.2 0.3 0.6 1.0 1.4 0.6 2.3
Type 2 Diabetes (T2D) (2018) 0.3 0.6 1.8 0.8 1.1 -0.6 -0.6 0.7 0.4 0.0 1.4
Lung FEV1/FVC ratio 0.2 1.1 3.4 -1.6 -0.8 -0.1 -1.8 -1.3 -0.2 0.0 -0.5
Lung FVC 0.2 1.1 3.5 -0.9 1.8 -0.6 1.9 -0.4 -0.3 -0.7 0.8
Neuroticism 0.7 1.6 5.1 0.1 1.1 1.5 0.4 1.1 2.3 0.5 1.7
Chronotype (morning person) 0.9 2.1 7.5 1.0 -0.5 -2.7 0.8 0.1 1.9 -0.4 -1.9
Hair Pigment 0.0 0.9 2.4 0.3 0.1 -0.1 1.4 0.1 -1.0 -1.1 -1.6
Tanning 0.1 1.6 7.2 -1.1 -0.4 -0.5 -1.1 -1.5 -0.0 0.2 2.7
Hand grip strength (left) 0.6 1.6 3.5 1.0 -1.1 0.1 -1.3 1.4 1.7 0.7 1.9
Number of treatments/medications taken 1.0 1.9 7.2 -0.2 1.7 1.1 2.7 -1.4 -0.4 0.2 1.1
Average weekly spirits intake 1.9 2.4 4.7 -1.6 2.2 0.5 1.8 -1.9 -1.7 0.1 1.2
Sensitivity / hurt feelings 0.7 1.3 3.6 -0.1 1.3 1.9 0.4 -0.7 0.2 1.1 1.7
Frequency of depressed mood in last 2 weeks 0.5 0.7 2.7 0.1 -0.8 -0.3 -0.4 1.3 0.3 -0.0 1.6
Hearing difficulty/problems: Yes 1.6 2.5 11.2 0.3 -1.2 2.0 -0.8 -0.4 0.9 3.3 1.1
Relative age of first facial hair 0.3 0.7 2.3 1.5 -0.6 0.5 0.8 1.0 -0.1 0.7 -0.4
Other serious medical condition/disability diagnosed by doctor 1.6 2.1 4.9 0.0 1.9 2.2 1.8 -1.7 -1.2 0.7 0.5
Ever used hormone-replacement therapy (HRT) 1.2 1.5 4.9 -2.2 -0.2 1.0 1.1 -1.8 -0.5 1.1 -0.1
Ever had hysterectomy (womb removed) 0.8 0.9 3.5 0.1 1.0 -0.3 0.9 -0.7 0.6 1.2 1.9
Systolic blood pressure, automated reading 0.7 2.0 6.7 -1.4 0.2 0.8 0.6 -0.2 -1.2 -2.2 -2.6
Eye problems/disorders: Diabetes related eye disease 1.0 1.1 3.7 0.9 1.2 -0.0 -0.5 0.8 0.2 -1.9 1.3
Angina 1.2 1.6 3.3 -1.8 1.1 1.3 1.8 -0.7 -1.7 0.1 0.3
Medication for hormone replacement therapy 0.6 0.7 2.8 -1.0 0.5 0.6 0.9 0.3 -0.1 1.7 -0.1
Vitamin and mineral supplements 1.0 1.3 4.6 0.9 -0.6 -0.9 -2.2 1.5 1.2 0.3 0.1
Supplements: Zinc 1.1 1.2 8.1 -0.2 0.3 -0.3 2.9 -0.7 -1.0 0.3 -0.0
Medication: Co-codamol 0.3 0.4 2.0 0.5 0.3 1.4 0.1 0.1 0.6 -0.3 -0.1
Medication: Metformin 1.0 1.4 4.0 -1.3 2.0 -0.5 -0.2 -0.6 -1.7 -1.3 -0.4
Diabetes (father) 0.5 0.6 1.4 -0.1 0.9 0.5 0.5 0.5 1.2 -0.5 -1.2
Diabetes (mother) 1.2 1.6 4.9 -1.8 -0.7 0.7 0.1 -1.6 -2.2 -1.0 0.1
Severe depression (siblings) 1.3 1.4 6.2 0.3 0.6 1.3 1.4 -0.8 0.4 2.5 0.5
Pack years adult smoking proportion 0.5 0.8 1.9 -1.4 -0.3 1.1 1.1 0.6 0.2 1.0 0.7
Impedance of leg (right) 0.1 0.5 1.1 -0.7 -0.6 0.8 1.0 1.1 -0.2 -0.4 -0.2
Leg fat-free mass (left) 0.3 1.8 6.9 0.9 -2.6 -0.6 -2.4 -0.8 0.4 0.2 0.5
Trunk fat percentage 0.8 3.2 10.0 0.1 -3.2 -0.4 -2.8 -2.8 -0.4 -0.1 0.3
Hand grip strength (right) 0.5 1.5 3.3 0.7 -0.4 -0.0 -1.6 1.8 1.7 -0.0 1.5
Townsend deprivation index at recruitment 0.8 1.2 6.2 1.0 -2.5 -0.4 -1.1 0.7 0.0 -0.2 -0.6
Current tobacco smoking 0.4 0.7 2.0 0.2 -1.4 -0.7 -0.4 0.8 0.1 1.4 -0.4
Average weekly fortified wine intake 0.8 0.9 2.5 -1.4 -1.0 -0.9 0.0 0.2 -1.6 -1.0 -0.2
Maternal smoking around birth 0.6 0.9 4.0 -0.2 0.8 0.4 2.0 -1.3 -0.6 0.0 -0.1
Fed-up feelings 0.9 1.7 7.6 -0.7 0.1 0.6 0.8 0.1 0.9 1.8 2.8
Frequency of unenthusiasm / disinterest in last 2 weeks 1.2 1.5 4.0 2.0 -0.2 1.2 0.1 1.1 -0.1 1.8 1.6
Relative age voice broke 0.6 1.0 4.3 0.4 -0.0 -0.2 2.1 -0.5 -0.7 0.3 1.5
Taking other prescription medications 1.0 1.6 5.1 1.0 1.2 0.9 1.0 -1.5 0.1 0.9 2.3
Age when periods started (menarche) 1.2 2.9 12.0 -0.7 -0.6 -0.6 0.9 1.2 -0.3 -3.5 -2.7
Bilateral oophorectomy (both ovaries removed) 0.4 0.4 1.7 -0.4 0.7 0.5 1.3 -0.5 -0.7 0.2 0.4
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.6 1.8 -0.8 -0.5 0.2 0.2 -1.3 -0.6 -0.5 1.1
Tinnitus: Yes, but not now, but have in the past 0.4 0.4 1.3 0.7 -0.7 1.1 -0.7 -0.1 -0.3 -0.1 -0.4
Qualifications: CSEs or equivalent 0.4 0.5 1.9 -0.2 1.2 1.4 -0.7 0.3 -0.2 -0.1 0.7
Serious illness, injury or assault to yourself 1.1 1.3 4.3 0.9 0.6 2.0 0.6 -0.1 2.1 0.3 0.8
High blood pressure 0.2 0.7 2.8 1.7 -0.6 0.7 -0.8 -0.5 -0.1 -0.9 -0.1
Hayfever, allergic rhinitis or eczema 0.5 1.2 3.4 -0.8 1.7 -0.2 1.8 -1.1 0.3 0.6 0.9
Multivitamins +/- minerals 0.9 1.1 4.5 -0.7 1.0 0.7 2.1 -0.9 -0.4 0.3 1.2
Stomach or abdominal pain in last month 1.3 1.7 4.7 1.6 -0.4 0.2 -0.2 -1.8 0.1 1.6 2.2
Supplements: Glucosamine 1.1 1.5 6.4 -0.4 0.1 -2.5 1.1 1.3 0.9 -1.1 0.6
Diverticular disease/diverticulitis (self-reported) 1.2 1.5 3.7 0.7 -1.8 -0.4 -0.0 -1.4 0.1 1.4 1.9
Medication: Atenolol 0.3 0.3 0.8 -0.8 -0.7 0.1 0.9 -0.1 0.2 -0.7 0.4
Medication: Levothyroxine sodium 0.8 1.4 5.7 1.1 2.4 1.8 0.2 -0.3 0.1 -1.1 -0.4
Sitting height 0.2 1.1 3.8 1.6 -1.9 0.1 -0.4 -0.2 0.2 -1.5 -0.2
Chronic bronchitis/emphysema (father) 1.5 1.7 4.3 -0.6 0.9 0.6 1.3 -2.0 -1.5 -0.3 -2.1
High blood pressure (mother) 0.8 1.2 3.5 -1.9 0.3 0.2 0.5 -1.3 -1.6 -1.1 0.1
Body mass index (BMI) 0.5 2.2 9.2 0.3 -2.1 0.5 -3.0 -1.6 -0.3 0.3 1.1
Impedance of leg (left) 0.1 0.5 1.3 -0.6 -0.4 0.7 0.8 1.0 -0.1 -1.1 -0.3
Leg predicted mass (left) 0.3 1.7 6.5 0.8 -2.5 -0.6 -2.3 -0.8 0.4 0.1 0.4
Trunk fat mass 0.9 3.9 14.1 0.4 -3.8 -0.4 -3.3 -2.4 -0.1 -0.0 0.7
Waist circumference 0.9 3.2 10.2 0.2 -3.0 -0.3 -3.2 -1.6 -0.2 0.4 1.8
Number of incorrect matches in round 3.1 5.2 12.6 -2.2 2.0 0.9 3.3 -0.8 -1.2 -2.6 -3.5
Past tobacco smoking 0.7 1.3 5.2 -0.1 1.0 0.6 0.5 -2.3 -0.7 -1.5 1.0
Alcohol usually taken with meals 0.9 1.4 6.8 -2.6 -0.5 -1.2 -0.5 -1.5 0.4 0.2 0.3
Nervous feelings 1.7 3.1 11.5 0.6 3.0 0.4 3.4 -0.1 0.8 -1.1 -1.4
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.6 2.3 0.6 0.3 0.0 1.0 1.5 -0.4 -1.1 -0.1
Hearing difficulty/problems with background noise 1.6 2.5 12.8 1.0 -0.6 1.7 -0.4 0.1 0.1 3.6 1.7
Hair/balding pattern: Pattern 2 1.5 1.9 5.5 -1.8 0.4 -0.6 2.0 -0.1 -2.3 -0.4 -1.3
Had menopause 2.3 2.9 9.9 -1.7 0.5 0.7 2.0 -1.9 -3.1 -1.0 -0.9
Had other major operations 0.9 1.1 4.7 0.8 0.3 2.2 -1.0 -1.5 -0.5 0.0 -0.2
Forced vital capacity (FVC) 0.3 1.3 3.0 -0.1 -0.5 -1.7 0.4 1.3 1.3 -1.7 0.7
Heel bone mineral density (BMD) T-score, automated (right) 0.4 1.0 2.5 -0.9 -0.7 0.9 -0.3 -1.5 -0.9 0.3 1.6
Ever unenthusiastic/disinterested for a whole week 0.7 0.9 3.4 -0.9 1.2 1.8 0.3 -0.8 0.1 0.7 0.2
Qualifications: None of the above 0.5 1.0 4.0 0.5 -0.7 2.0 0.5 -0.4 -1.3 0.7 0.7
Financial difficulties in last 2 years 0.9 1.2 3.8 0.4 -0.4 1.3 -1.4 1.1 0.2 0.8 2.0
Mouth/teeth dental problems 0.4 0.7 1.4 -1.1 -1.2 -0.4 -0.9 0.9 -0.0 -0.5 0.9
Heart attack 1.1 1.3 3.0 -1.7 0.0 0.3 1.1 -0.5 -1.2 -1.4 -1.7
Allergy 0.5 1.2 2.9 0.1 -0.4 -1.0 -1.2 0.8 -0.8 -1.6 -1.7
Pain all over the body in last month 0.8 0.9 3.1 0.1 0.5 0.7 1.8 -1.3 -0.4 0.5 1.0
Diabetes (self-reported) 0.3 0.4 1.8 -0.2 1.3 -0.0 0.6 -0.6 -0.6 -0.3 0.0
Hayfever/allergic rhinitis (self-reported) 1.4 1.8 4.7 -2.0 0.0 -0.5 2.2 -1.6 -1.6 -0.0 0.5
Medication: Ramipril 0.8 1.0 3.3 0.0 -1.3 -1.8 -1.0 -0.5 0.0 -0.4 -1.4
Medication: Simvastatin 0.4 0.6 1.2 -1.1 -0.5 -1.1 0.3 -1.1 -0.3 -0.3 -0.8
Fluid intelligence score 1.0 2.1 9.8 1.6 0.2 -3.1 -1.8 0.5 0.3 0.0 0.8
Illnesses of siblings 0.6 0.9 2.5 -1.1 0.4 0.4 -1.6 1.2 0.6 -1.1 -0.3
Neuroticism score 0.7 1.4 2.4 -0.5 1.3 1.4 1.4 0.9 1.3 -0.5 1.6
Weight 0.7 3.4 12.7 0.6 -3.6 0.2 -3.4 -1.2 0.0 -0.1 1.2
Impedance of arm (right) 0.2 0.8 2.5 -0.9 0.4 -0.3 1.3 -0.4 -0.4 -1.0 -1.6
Arm fat percentage (right) 0.6 2.4 8.3 0.1 -2.4 0.1 -2.9 -2.0 -0.3 0.5 0.8
Trunk fat-free mass 0.3 2.0 8.9 0.7 -3.0 -0.4 -2.0 0.7 0.4 0.2 1.2
Hip circumference 0.9 3.7 11.5 0.5 -3.4 0.5 -3.1 -1.8 -0.6 0.1 2.1
Time employed in main current job 1.5 1.7 6.2 -0.7 1.6 -0.3 1.3 0.7 0.4 -2.5 -1.3
Alcohol intake versus 10 years previously 1.2 1.8 6.5 0.7 -1.5 0.5 -2.5 0.7 0.6 1.1 1.8
Father’s age at death 0.1 0.2 0.8 -0.3 0.2 0.1 0.3 0.3 -0.1 0.9 0.6
Worrier / anxious feelings 1.4 2.7 11.3 -1.1 3.4 1.9 1.6 1.2 1.0 -0.4 0.3
Frequency of tiredness / lethargy in last 2 weeks 0.7 1.2 6.2 2.5 -0.4 0.9 0.0 0.0 0.8 0.6 1.3
Falls in the last year 0.3 0.4 1.4 0.1 -0.8 0.3 1.2 -0.0 0.5 0.6 0.4
Hair/balding pattern: Pattern 3 0.6 0.8 2.7 1.6 0.7 1.1 0.1 -0.6 0.9 1.0 0.5
Number of live births 1.2 1.7 7.8 -0.1 0.9 1.3 -0.5 -1.2 -0.8 2.8 0.8
Forced expiratory volume in 1-second (FEV1) 0.3 1.0 4.9 -0.6 -0.4 -1.0 -0.3 0.4 1.0 -2.2 0.1
Pulse rate 1.2 2.1 5.8 2.4 -0.0 0.1 -1.0 1.4 2.1 -1.8 0.1
Happiness 0.8 0.9 3.1 0.2 1.0 -0.2 -0.2 -0.4 -0.9 1.5 1.8
Noisy workplace 1.5 1.8 11.5 -0.1 0.9 3.4 0.0 0.8 0.3 0.9 0.9
Qualifications: A levels/AS levels or equivalent 0.8 1.7 4.6 1.3 -0.7 -2.1 -0.2 -0.1 0.5 2.0 1.5
Serious illness, injury or assault of a close relative in last 2 years 0.7 0.8 2.5 -1.2 -0.4 -1.1 1.6 0.1 -0.7 -0.3 0.5
Mouth/teeth dental problems: Dentures 0.5 0.9 2.8 0.8 -1.0 -0.1 -0.2 -0.5 -0.6 1.7 1.4
Asthma 1.1 2.1 4.6 1.3 -2.1 -0.3 1.0 0.6 1.9 1.3 2.0
Medication: Ibuprofen (e.g. Nurofen) 0.6 0.8 1.7 0.5 0.7 0.7 0.3 1.1 1.3 -0.8 1.3
Medication: Cholesterol lowering 0.4 0.6 1.5 -1.1 -0.3 -0.6 0.3 -1.2 0.3 -0.8 -1.0
Depression (self-reported) 0.6 0.7 2.0 -0.1 1.0 -0.3 1.4 -0.1 0.1 -1.4 0.9
Medication: Lansoprazole 0.5 0.6 1.9 -0.8 0.5 -0.2 1.4 -0.3 -0.8 0.8 0.9
Prospective memory result 1.7 2.1 8.6 0.1 2.9 1.6 1.8 -1.4 -0.2 0.2 -0.7
Lung cancer (father) 1.1 1.3 3.5 -1.2 0.6 -1.6 -1.4 1.9 -0.3 0.7 0.1
Illnesses of mother 0.4 0.5 1.4 0.8 0.5 0.2 0.6 1.2 0.7 0.5 -0.7
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.8 3.1 0.6 -0.5 -0.9 -0.8 0.3 1.0 -1.8 -0.0
Pulse wave Arterial Stiffness index 0.4 0.4 1.1 0.5 0.2 0.5 -1.1 -0.7 0.6 0.9 0.1
Impedance of arm (left) 0.2 0.7 2.8 -0.4 0.3 -0.4 1.1 -0.9 -0.2 -0.7 -1.7
Arm fat mass (right) 0.7 2.9 10.1 0.4 -3.0 0.3 -3.2 -1.7 0.0 0.2 0.9
Trunk predicted mass 0.4 2.1 9.2 0.7 -3.0 -0.4 -2.1 0.8 0.5 0.1 1.1
Standing height 0.2 2.0 12.4 0.9 -3.5 -0.5 -1.2 0.6 0.7 -0.8 0.2
Length of working week for main job 0.3 0.4 1.2 0.5 0.3 -0.4 0.5 0.5 0.4 0.7 1.1
Exposure to tobacco smoke at home 0.5 0.6 1.1 0.9 0.2 0.5 0.5 -1.0 1.0 1.0 -0.3
Breastfed as a baby 1.2 1.5 5.2 2.3 -0.9 0.3 -1.0 0.7 1.0 1.7 -0.9
Tense / ‘highly strung’ 1.3 2.1 5.0 2.2 0.8 1.0 2.2 0.1 1.6 0.9 1.4
Seen doctor (GP) for nerves, anxiety, tension or depression 2.0 3.1 9.0 -0.0 2.7 0.6 2.7 -0.9 -0.1 0.6 3.0
Hair/balding pattern: Pattern 4 0.5 1.2 3.1 -1.0 0.3 1.1 -0.2 -1.1 -1.4 -1.2 -1.8
Birth weight of first child 0.9 1.6 4.8 -1.4 0.8 -0.7 0.4 -0.6 0.1 -2.2 -1.9
Peak expiratory flow (PEF) 0.3 0.7 3.5 -0.7 -0.8 -0.6 0.7 -0.2 0.6 -0.1 1.9
Pulse wave reflection index 0.5 0.6 2.2 0.2 -0.4 0.0 0.1 -0.8 -0.4 1.5 1.2
Ever highly irritable/argumentative for 2 days 0.2 0.3 0.7 -0.2 -0.8 0.9 -0.0 0.2 0.3 0.5 -0.9
Loud music exposure frequency 0.3 0.3 1.2 0.7 -0.5 -0.6 -1.1 -0.2 -0.2 -0.1 0.5
Qualifications: O levels/GCSEs or equivalent 1.2 1.9 7.0 -0.3 -0.2 -0.3 -1.9 1.6 2.6 -0.1 1.3
Mouth/teeth dental problems: Bleeding gums 0.7 0.9 4.1 0.2 0.5 -0.5 1.0 -0.6 -0.2 -1.1 -2.0
Blood clot in the leg (DVT) 1.4 1.8 7.6 1.3 1.3 1.5 1.1 -2.8 -0.1 0.4 0.4
Medication: Paracetamol 0.9 1.5 4.9 -0.8 0.3 1.0 1.3 2.2 0.6 -0.1 1.9
Headache pain in last month 0.5 0.9 2.8 -1.0 0.3 0.9 0.5 0.7 0.4 1.3 1.7
Medication for cholesterol, blood pressure or diabetes 0.3 0.4 1.2 0.7 0.2 0.4 0.0 0.6 -0.5 1.1 0.8
Glaucoma (self-reported) 1.3 1.5 6.8 -1.3 -2.6 -0.3 -0.2 -0.7 -0.9 -1.3 -0.4
Gout (self-reported) 0.8 1.0 2.6 -0.5 -0.7 -1.6 -1.6 1.1 -0.4 -0.5 -0.8
Hypothyroidism/myxoedema (self-reported) 0.8 1.5 5.6 0.6 2.4 1.5 -0.1 -0.9 0.1 -1.4 -1.1
Medication: Amlodipine 0.1 0.1 0.4 -0.2 0.6 0.3 -0.3 -0.2 0.2 -0.6 0.1
Medication: Ventolin 100micrograms inhaler 0.2 0.3 0.5 -0.6 -0.3 -0.6 0.7 0.2 0.5 0.2 -0.6
Birth weight 0.3 0.6 2.9 1.7 -0.7 0.0 -0.7 0.7 0.2 0.5 0.7
Chronic bronchitis/emphysema (mother) 0.4 0.4 1.3 0.5 -0.6 0.4 0.1 -0.9 0.2 0.6 1.1
High blood pressure (siblings) 0.8 1.2 3.3 -0.2 1.4 0.1 1.8 -1.6 -0.9 0.3 0.8
Forced vital capacity (FVC), Best measure 0.2 0.9 1.7 0.9 -0.7 -0.7 -0.6 1.3 1.3 -1.0 0.7
Body fat percentage 0.8 3.3 10.0 0.1 -3.2 0.1 -3.0 -2.6 -0.5 0.2 0.7
Leg fat percentage (right) 0.9 3.3 10.8 -0.3 -3.3 0.8 -2.6 -2.3 -0.9 0.7 1.4
Arm fat-free mass (right) 0.5 2.5 10.5 0.9 -3.2 -0.4 -2.6 0.4 0.6 -0.1 1.2
Exposure to tobacco smoke outside home 0.4 0.6 1.3 -0.0 0.3 1.1 -0.6 0.9 -0.4 0.9 1.1
Comparative body size at age 10 0.4 1.0 6.6 -0.3 0.5 -0.5 -2.6 -0.4 -0.1 0.8 -0.4
Number of full brothers 0.6 0.8 1.8 0.2 1.2 1.1 0.8 1.4 0.5 0.8 0.3
Worry too long after embarrassment 1.0 1.7 9.2 0.3 1.8 3.0 0.4 0.4 0.5 0.5 -0.3
Seen a psychiatrist for nerves, anxiety, tension or depression 0.8 1.0 3.7 -1.1 -0.1 -0.2 1.5 0.0 -0.8 -0.5 1.9
Wheeze or whistling in the chest in last year 1.2 2.2 9.5 1.3 -3.1 -0.2 0.4 2.1 1.1 -0.4 0.7
Number of children fathered 1.6 1.8 9.2 0.1 -0.3 1.2 0.1 -0.1 1.1 1.5 3.0
Reason for reducing amount of alcohol drunk: Health precaution 0.5 0.5 2.3 -1.5 0.2 0.7 0.8 0.6 -0.6 0.3 -0.1
Age at first live birth 0.3 0.5 1.7 -0.7 0.2 -1.3 0.6 0.4 -0.5 -0.7 -0.4
Pulse wave peak to peak time 0.3 0.4 0.9 -0.5 -0.4 -0.6 0.8 0.5 -0.7 -1.0 -0.1
Health satisfaction 0.2 0.3 1.4 0.0 -0.3 0.2 -0.8 0.2 0.2 0.1 1.2
Shortness of breath walking on level ground 0.6 0.7 3.5 0.2 -0.3 1.9 0.6 0.9 0.7 -0.3 0.2
Qualifications: College or University degree 0.7 2.2 11.8 0.4 -0.5 -3.4 1.2 -0.7 -1.0 1.2 -0.9
Eye problems/disorders: None of the above 1.1 1.2 4.3 -0.7 0.4 -0.6 -2.0 -0.1 0.5 2.1 -0.1
Mouth/teeth dental problems: Loose teeth 1.0 1.2 3.2 -0.7 1.4 0.8 0.7 -1.3 -0.6 0.4 -1.8
Emphysema/chronic bronchitis 0.7 0.8 2.1 -0.0 -1.0 0.6 0.5 1.5 0.2 1.3 1.1
Medication for pain relief, constipation, heartburn 0.5 0.8 3.5 0.3 -0.3 0.6 -1.9 -0.5 -0.5 0.2 -1.5
Neck or shoulder pain in last month 0.9 1.3 4.6 -0.4 0.5 2.1 0.2 -0.8 -1.5 0.5 1.6
Medication: Blood pressure 0.1 0.2 0.5 -0.2 0.5 0.2 -0.1 -0.3 0.4 -0.7 -0.5
Angina (self-reported) 1.1 1.4 3.2 -1.8 1.2 1.2 1.5 -0.4 -1.6 0.1 0.4
Migraine (self-reported) 1.0 1.2 4.4 1.2 0.6 0.5 -0.5 1.7 0.1 0.5 2.1
Medication: Ibuprofen 0.5 0.6 2.1 0.5 0.3 0.7 0.5 1.0 0.6 -0.3 1.5
Medication: Allopurinol 0.3 0.4 1.6 -0.8 0.3 -0.1 -0.9 1.3 0.2 0.3 -0.5
Medication: Omeprazole 0.7 0.8 4.2 0.0 -0.4 0.2 -0.5 -2.0 0.2 0.1 1.3
Medication: Seretide 50 evohaler 2.2 2.6 9.7 1.8 -0.2 0.3 -0.1 -0.1 1.4 2.3 3.1
Mean time to correctly identify matches 1.3 2.4 4.7 -2.0 -0.5 -0.6 1.7 -1.6 -2.2 -0.3 -2.1
Heart disease (mother) 0.6 0.7 3.1 0.2 -0.9 -0.8 -1.8 0.2 0.6 -0.8 -0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.4 1.7 6.2 -1.1 -1.0 -1.8 0.7 1.3 0.0 -2.5 0.5
Whole body fat mass 0.9 3.6 12.3 0.4 -3.5 0.1 -3.2 -2.2 -0.1 0.2 1.1
Leg fat mass (right) 1.0 3.7 11.9 0.4 -3.5 0.6 -3.2 -2.0 -0.5 0.6 1.5
Arm predicted mass (right) 0.4 2.3 9.3 0.9 -3.0 -0.4 -2.5 0.3 0.4 -0.1 1.0
Pulse rate, automated reading 0.2 0.8 1.8 1.4 0.2 -0.5 -0.8 -0.2 1.2 -0.8 -1.2
Alcohol intake frequency. 0.6 1.5 3.5 1.3 -1.2 1.3 -1.2 -1.9 0.6 -0.4 1.3
Comparative height size at age 10 0.2 0.9 4.1 1.1 -2.0 0.3 -0.5 -0.4 0.4 -1.1 0.5
Number of full sisters 0.7 0.8 2.8 1.0 -0.8 -0.6 -0.1 -0.3 -1.1 1.7 0.8
Suffer from ‘nerves’ 2.0 3.1 9.3 -0.1 1.3 1.0 -0.4 2.8 2.2 -3.0 0.1
Overall health rating 0.8 1.8 8.6 1.7 -0.3 1.1 -0.7 -0.4 -0.1 1.0 2.9
Chest pain or discomfort 0.6 0.8 2.7 -0.1 -0.2 1.4 0.4 0.9 0.8 -0.4 1.6
Had major operations 1.0 1.1 3.0 0.9 1.7 0.4 1.2 -1.1 1.2 0.7 -0.7
Age at last live birth 0.7 0.9 4.0 -2.0 -0.7 -1.1 0.8 -0.3 -0.3 0.1 1.0
Family relationship satisfaction 0.7 0.9 5.4 -2.3 0.1 -0.2 0.1 0.6 -0.5 0.7 0.8
Leg pain on walking 1.4 1.7 5.2 0.3 1.5 2.2 -0.1 0.8 0.4 0.8 2.3
Qualifications: NVQ or HND or HNC or equivalent 0.8 1.0 2.2 1.0 -0.9 0.1 -1.1 1.0 1.3 0.2 1.5
Commuting to job workplace: Car/motor vehicle 0.9 1.0 2.7 0.8 -0.1 1.5 -1.2 0.3 0.7 -0.8 1.7
Illness, injury, bereavement, stress in last 2 years 0.7 0.8 2.0 0.9 0.0 -1.3 -0.1 -1.4 0.1 1.4 -0.2
Medication: Aspirin 1.2 1.6 7.9 0.2 0.4 -0.9 2.8 0.6 0.2 -0.1 -1.8
Supplements: Vitamin C 1.2 1.5 5.4 -0.7 0.1 1.5 2.3 -1.3 -1.1 0.5 -0.5
Knee pain experienced in last month 1.3 2.0 4.3 1.6 0.0 1.9 -1.2 -0.6 0.0 2.0 2.1
Hypertension (Self-reported) 0.2 0.7 1.6 1.3 -0.7 0.7 -0.5 -1.2 -0.3 -1.0 -0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.6 0.7 3.0 -1.4 -0.2 -0.2 0.6 0.2 0.1 0.6 1.7
Illnesses of father: Heart disease 0.2 0.2 0.7 -0.2 -0.8 0.7 -0.6 -0.1 -0.2 -0.1 0.3
Illnesses of siblings: Diabetes 0.7 0.9 1.9 0.9 -0.7 -1.2 0.5 -1.4 -0.3 0.5 1.4
Smoking status: Previous 0.4 0.6 2.0 0.1 -0.5 -0.3 -0.3 1.4 0.7 1.1 -0.4
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.9 3.3 -0.0 -1.5 -1.8 -0.5 0.6 0.6 -0.6 0.1
Whole body fat-free mass 0.4 2.0 8.5 0.9 -2.9 -0.4 -2.4 0.2 0.5 0.1 0.8
Leg fat-free mass (right) 0.3 1.6 5.4 0.9 -2.3 -0.8 -2.2 -0.7 0.5 -0.2 0.5
Arm fat percentage (left) 0.7 2.8 9.7 0.4 -2.6 -0.0 -3.1 -2.1 -0.0 0.6 0.8
Average weekly red wine intake 0.6 0.9 2.9 0.0 -1.5 -1.7 -0.2 1.2 0.1 -0.2 -0.4
Handedness (chirality/laterality): Left-handed 1.5 1.8 6.1 0.2 0.4 1.9 0.8 1.3 1.4 -0.7 -2.5
Mood swings 0.6 1.1 4.9 -0.6 0.1 1.1 -0.6 1.4 0.5 0.1 2.2
Loneliness, isolation 1.4 1.9 9.7 -1.2 -1.6 -0.6 -0.0 1.1 -0.0 -0.2 3.1
Long-standing illness, disability or infirmity 1.3 2.0 10.5 0.5 0.5 0.2 1.2 -3.2 -0.2 1.0 1.6
Ever had bowel cancer screening 1.2 1.4 5.6 0.9 0.9 1.4 2.4 -1.3 -0.6 -0.2 -0.6
Diabetes diagnosed by doctor 0.2 0.3 1.6 0.1 1.3 -0.4 0.2 0.0 -0.2 -0.4 0.9
Ever had stillbirth, spontaneous miscarriage or termination 1.2 1.3 4.1 0.6 -1.1 -0.9 -0.1 0.3 1.2 2.0 1.4
Friendships satisfaction 0.3 0.4 1.4 -0.3 -1.0 0.3 0.1 0.1 -0.5 0.6 1.2
Qualifications: nursing, teaching 0.7 1.1 3.8 0.9 1.1 -0.4 1.1 -0.5 -0.0 1.9 1.1
Commuting to job workplace: Walk 1.1 1.2 6.2 0.1 -0.6 -2.5 1.2 0.1 -0.3 -0.4 -1.2
Eye problems/disorders: Cataract 0.9 1.1 4.7 0.7 -0.4 -0.3 2.2 0.0 -0.5 -1.2 -1.1
Mouth/teeth dental problems: Mouth ulcers 1.1 1.8 4.9 -0.5 2.2 1.0 1.4 -1.2 -0.1 -1.1 -1.9
Medication for cholesterol 0.3 0.4 1.2 -0.1 0.4 0.7 -0.1 1.0 1.1 -0.5 -0.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.0 1.2 3.9 1.0 -0.3 1.4 0.3 -1.2 -2.0 0.0 1.0
Back pain experienced in last month 0.9 1.3 2.7 0.1 0.7 0.8 0.0 1.6 1.4 1.3 1.6
Mineral and other dietary supplements 0.5 0.7 2.9 0.1 0.4 1.7 -1.2 -0.4 -0.0 0.6 -0.7
Breast cancer (self-reported) 1.3 1.5 3.4 -0.4 0.6 0.8 1.4 -1.9 -1.4 1.6 1.0
Asthma (self-reported) 1.0 1.9 4.5 1.2 -2.1 -0.2 0.8 0.6 1.8 1.1 1.9
Osteoporosis (self-reported) 0.5 0.6 3.0 0.3 0.6 0.3 -0.8 0.8 0.5 -0.0 -1.7
Osteoarthritis (self-reported) 0.4 0.5 2.0 -1.0 0.5 1.4 0.5 0.2 -0.6 -0.1 0.0
Medication: Aspirin 1.5 2.0 7.7 0.3 -0.0 -0.4 2.8 0.9 0.3 -1.0 -2.4
Medication: Gliclazide 0.6 0.6 2.2 -0.9 1.5 0.9 -0.2 -0.7 0.2 -0.0 -0.8
Illnesses of father: None of the above (group 1) 0.7 0.9 2.7 -0.3 -0.4 -1.7 -1.4 1.5 -0.0 0.2 -0.4
Smoking status: Current 0.5 0.8 2.3 0.4 -1.5 -0.4 -0.8 0.8 0.5 1.5 -0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.4 0.9 3.9 -0.5 -0.7 -0.3 -0.6 0.4 0.1 -2.0 -1.3
Whole body water mass 0.4 2.1 8.7 1.0 -2.9 -0.6 -2.3 0.4 0.7 0.1 0.9
Leg predicted mass (right) 0.3 1.6 5.4 0.9 -2.3 -0.8 -2.2 -0.7 0.5 -0.1 0.5
Arm fat mass (left) 0.7 3.0 11.6 0.6 -2.9 0.1 -3.4 -1.5 0.2 0.4 1.0
Number of self-reported non-cancer illnesses 1.1 1.9 7.7 0.5 0.5 0.7 1.1 -2.8 -1.6 1.0 1.3
Average weekly champagne plus white wine intake 0.6 0.8 5.4 -0.1 -0.3 0.1 -2.3 -0.2 0.7 -0.1 0.3
Miserableness 0.6 1.0 4.1 0.1 -1.5 0.2 -0.1 0.9 0.3 0.8 2.0
Guilty feelings 0.5 0.8 3.1 -1.2 0.5 1.8 0.9 -0.1 -0.7 -0.2 -0.2
Wears glasses or contact lenses 0.6 0.7 1.6 0.9 -1.2 -0.2 -0.7 -0.4 0.3 1.3 0.9
Ever taken oral contraceptive pill 1.2 1.3 2.8 1.2 -0.5 -0.5 -0.2 1.4 1.7 1.1 1.6
Hearing aid user 1.7 1.9 6.3 0.4 -0.5 1.7 -0.6 -0.0 1.2 1.9 2.5
Mother’s age at death 0.2 0.3 0.8 0.5 0.6 -0.9 -0.6 0.0 0.5 0.2 -0.3
Financial situation satisfaction 0.9 1.1 2.4 0.7 -1.0 -1.5 -1.2 0.7 0.4 -0.8 1.6
Tinnitus: Yes, now most or all of the time 1.1 1.2 4.9 0.8 1.0 -0.5 1.1 0.8 2.2 0.7 0.8
Commuting to job workplace: Public transport 0.8 0.9 4.6 -0.8 -0.6 -2.1 0.7 -0.0 -1.1 0.2 -0.5
Eye problems/disorders: Glaucoma 1.8 2.2 10.9 -1.4 -3.3 -0.1 -0.2 0.1 -0.6 -2.0 -0.4
Medication: Blood pressure 0.2 0.3 0.6 0.3 -0.8 -0.1 -0.6 -0.7 -0.6 -0.6 -0.2
Pain type(s) experienced in last month: Hip pain 2.9 3.7 12.2 1.1 1.8 -0.3 0.4 -0.3 1.1 3.4 3.5
Supplements: Fish oil (including cod liver oil) 0.5 0.6 2.7 -0.2 0.1 -0.0 1.6 1.1 -0.1 -0.6 0.9
High cholesterol (Self-reported) 0.7 1.3 5.0 0.1 -2.2 -1.1 0.1 -1.5 -0.8 0.7 1.0
Medication: Bendroflumethiazide 0.2 0.3 0.9 -0.7 -0.1 0.1 -0.2 -0.0 -0.9 -0.3 -0.7
Medication: Paracetamol 1.6 2.5 4.6 -2.0 0.4 1.4 2.1 2.1 -0.4 0.2 2.1
Medication: Lisinopril 0.8 1.0 3.2 0.6 -0.3 1.8 0.6 0.7 0.7 -1.8 0.4
Medication: Atorvastatin 0.4 0.5 1.4 0.9 -0.4 -0.7 0.3 -0.8 -0.7 0.3 1.2
Illnesses of father: High blood pressure 0.4 0.5 0.8 0.9 -0.2 0.9 0.2 -0.8 0.9 -0.9 0.7
Alcohol drinker status: Never 1.2 1.5 4.6 1.4 -1.0 0.3 -0.6 -0.7 0.4 1.8 2.1
Ever smoked 1.2 2.1 7.2 0.3 -1.8 -0.6 -0.9 2.7 0.9 1.5 -1.5
Basal metabolic rate 0.4 2.3 9.7 0.9 -3.1 -0.4 -2.7 -0.2 0.4 0.0 0.9
Leg fat percentage (left) 0.9 3.4 9.7 -0.1 -3.1 0.6 -2.9 -2.5 -0.9 0.3 1.3
Arm fat-free mass (left) 0.5 2.4 10.8 0.8 -3.3 -0.3 -2.5 0.6 0.5 0.0 1.1
Number of operations (self-reported) 1.1 1.6 4.2 1.6 0.7 2.1 0.6 -0.9 1.6 1.3 0.5
Average weekly beer plus cider intake 0.4 0.5 2.4 0.4 0.4 1.1 -1.6 0.5 -0.1 0.1 -0.1
Irritability 1.4 2.3 7.0 0.8 -0.4 -0.7 1.3 1.2 2.2 1.4 2.6
Risk taking 0.9 1.3 3.3 0.2 -1.3 -0.7 0.9 1.4 -0.6 1.8 1.3
Ever had prostate specific antigen (PSA) test 0.4 0.5 1.2 0.6 0.7 0.1 1.1 -0.5 0.0 1.0 0.7
Fractured/broken bones in last 5 years 0.5 0.6 1.6 0.7 -1.2 -0.8 0.5 -0.9 0.1 -0.9 0.3
Age started oral contraceptive pill 1.3 1.7 4.8 -1.2 0.8 1.1 1.7 -2.2 -1.2 -0.4 -0.8
Diastolic blood pressure, automated reading 0.4 1.2 2.8 -1.1 -0.9 0.2 -1.2 0.6 -0.9 -1.7 -1.6
Ever depressed for a whole week 0.4 0.5 1.2 -0.5 -0.3 1.1 0.1 1.0 0.9 0.3 0.7
Unable to work because of sickness or disability 0.3 0.4 1.2 1.1 0.5 1.0 -0.6 0.1 -0.2 0.6 0.5
Commuting to job workplace: Cycle 0.6 0.7 1.7 0.5 -0.2 -1.3 0.7 0.6 0.7 1.2 -0.8
Myopia 1.0 1.4 4.4 -0.8 2.1 -0.3 1.2 -1.0 0.1 1.8 -0.8
Vascular/heart problems diagnosed by doctor 0.2 0.5 1.1 -1.0 0.1 -0.6 0.0 1.1 0.7 1.0 0.4
Cholesterol lowering medication 0.8 1.2 4.2 -0.2 -0.7 -0.3 0.5 -2.0 -1.8 0.6 0.9
Medication: Omeprazole (e.g. Zanprol) 0.6 0.8 3.8 -0.7 -0.0 -0.1 -0.1 -2.0 0.1 0.7 1.1
Pain experienced in last month 0.2 0.3 1.5 -0.6 -0.2 -1.2 0.6 0.1 -0.1 -0.1 -0.7
Supplements: Calcium 1.0 1.1 3.9 -0.3 1.1 -0.6 2.0 -1.3 -0.9 -0.9 0.1
Basal cell carcinoma (self-reported) 0.6 0.7 1.7 0.7 -1.2 -0.9 1.0 1.3 0.5 0.6 0.3
Heart attack/myocardial infarction (self-reported) 1.2 1.5 2.9 -1.7 0.2 0.3 1.3 -0.7 -1.5 -1.4 -1.7
Deep venous thrombosis (DVT) (self-reported) 1.1 1.4 5.3 1.4 1.1 1.3 0.8 -2.3 -0.0 0.3 0.3
Heart disease (siblings) 0.4 0.5 1.7 -0.4 -0.3 0.2 1.3 0.2 0.3 1.3 0.4
Alcohol drinker status: Previous 0.4 0.4 1.0 0.8 0.1 -1.0 0.3 -1.0 0.7 -0.5 0.0
Pack years of smoking 0.7 1.0 2.2 -1.4 -0.4 1.5 1.2 0.2 0.1 1.0 1.0
Impedance of whole body 0.1 0.5 1.8 -0.5 -0.1 0.1 0.9 -0.1 -0.3 -1.0 -1.3
Leg fat mass (left) 1.0 3.8 12.2 0.5 -3.4 0.4 -3.5 -2.0 -0.4 0.3 1.4
Arm predicted mass (left) 0.5 2.3 8.9 0.7 -3.0 -0.1 -2.6 0.5 0.6 -0.0 1.2