Hub : Genes

GPR137B

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Cells Transformed fibroblasts 0.324 0.0620 5.9e-09 0.195 NA 0.217 NA 0.223 1.4e-14 NA 3.2e-16 NA 1.1e-16
2 GTEx Heart Atrial Appendage 0.392 0.0790 6.0e-07 0.311 NA 0.266 NA 0.283 1.7e-14 NA 2.4e-12 NA 3.7e-13
3 GTEx Nerve Tibial 0.158 0.0523 1.5e-03 0.090 NA 0.078 NA 0.089 5.9e-07 NA 3.3e-06 NA 7.4e-07
4 GTEx Thyroid 0.148 0.0540 4.3e-03 0.023 NA 0.054 NA 0.036 7.1e-03 NA 6.0e-05 NA 9.1e-04
5 GTEx Uterus 0.556 0.1440 6.1e-03 0.075 NA 0.058 NA 0.073 1.3e-02 NA 2.6e-02 NA 1.4e-02
6 METSIM Adipose 0.152 0.0445 9.3e-05 0.063 0.055 0.114 0.074 0.102 9.7e-10 1.3e-08 9.7e-17 3.1e-11 5.1e-15
7 YFS Blood 0.342 0.0385 0.0e+00 0.125 0.126 0.154 0.134 0.154 1.5e-38 4.2e-39 5.8e-48 1.4e-41 6.6e-48
8 TCGA Glioblastoma Multiforme 0.165 0.0730 5.8e-03 0.026 0.096 0.033 NA 0.046 5.4e-02 7.6e-04 3.5e-02 NA 1.6e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.6 1.0 3.1 0.5 1.1 1.0 -0.2 -1.3 1.8 0.9 -0.1
Bipolar Disorder or Schizophrenia 0.6 1.4 3.4 0.1 1.8 1.8 0.3 -1.6 1.0 0.5 0.8
Depressed Affect (Nagel 2018) 0.3 0.7 5.0 -0.3 -0.2 -0.2 -0.2 -0.5 0.0 -0.0 -2.2
Depression (Nagel 2018) 0.5 0.8 2.5 -0.7 1.4 1.6 -1.2 -0.5 -0.3 -0.1 0.1
Intelligence (Savage-Jansen 2018) 0.9 2.9 6.9 1.2 -1.6 -1.6 0.7 -0.3 2.5 2.6 -1.6
Neuroticism (Nagel 2018) 0.5 1.2 5.2 -0.6 -1.3 -1.0 -0.3 -0.6 -0.7 -0.4 -2.3
Schizophrenia (2018) 0.4 0.8 2.4 -0.2 1.4 1.5 0.6 -1.0 0.0 -0.0 1.1
Schizophrenia vs Biploar Disorder 0.4 0.5 1.4 -0.4 -0.3 -0.9 0.5 -1.0 -0.8 0.2 -1.2
Worry (Nagel 2018) 0.5 1.0 2.3 -0.7 -1.5 -1.3 0.1 -0.7 -0.4 -0.7 -1.4
Alzheimer’s Disease (in mother) 0.4 0.4 2.7 -1.6 -0.5 -0.2 -0.5 0.4 0.2 -0.2 -0.2
Alzheimer’s Disease (in father) 0.7 0.8 3.0 -0.7 0.1 0.4 -1.2 -1.7 -0.7 -0.9 0.2
Alzheimer’s Disease (including proxy) 0.5 0.8 2.2 -1.5 0.6 1.1 -0.9 -0.6 -0.0 -0.6 0.9
Crohns Disease (2017) 0.3 0.6 2.0 0.1 -1.1 -0.9 -0.4 -0.3 0.1 -0.4 -1.4
Irritable Bowel Disease (IBD) 0.2 0.5 1.5 -0.1 -0.9 -0.8 -0.8 -0.2 -0.3 -0.7 -1.2
Ulcerative Colitis (UC) 0.2 0.3 1.5 -0.3 -0.4 -0.2 -1.2 -0.1 -0.4 -0.5 -0.6
Major Depression (MDD) 1.7 2.1 5.8 1.7 0.1 0.3 1.0 0.5 2.2 2.4 1.6
Reaction Time 0.4 0.7 1.6 -0.8 0.4 0.9 -1.3 0.2 -0.9 -1.0 0.5
Verbal and Numeric Reasoning (VNR) 0.3 0.7 1.8 0.1 0.2 0.1 0.2 -0.8 1.3 1.1 -1.3
Breast Cancer 0.3 0.8 4.5 -0.2 0.5 0.7 -0.8 2.1 -0.1 0.1 0.9
Ovarian Cancer 1.7 2.2 4.1 1.8 1.5 0.4 2.0 1.7 0.7 0.9 1.9
Prostate Cancer 0.8 1.2 2.5 -0.9 -0.4 -0.9 -1.5 -0.3 -1.5 -1.6 -0.6
Age at First Birth 0.3 0.4 1.4 -0.1 -1.2 -1.0 0.6 -0.5 -0.4 -0.3 -0.1
Bipolar Disorder (2011) 0.2 0.2 0.6 -0.0 -0.5 -0.4 -0.8 -0.0 0.0 0.6 -0.3
Body Mass Index (BMI) (2010) 0.3 0.4 1.2 1.1 -0.1 -0.2 0.9 -0.4 0.7 0.4 0.1
Coronary Artery Disease (CAD) 0.5 0.6 1.6 1.3 0.2 0.4 0.9 -1.0 0.0 1.0 0.6
Crohns Disease (2012) 0.3 0.5 1.5 -0.7 -1.2 -0.6 -0.1 0.5 -0.8 -0.6 -0.6
Mean Putamen Volume 1.0 1.1 4.3 -2.1 -0.0 0.3 -1.7 -0.4 -0.7 -1.0 -0.4
Fasting Glucose 0.3 0.3 1.0 -0.0 -0.3 0.2 -0.4 -1.0 0.8 0.1 -0.8
HbA1C 3.2 3.5 8.0 2.8 0.0 -0.3 2.4 1.2 2.8 2.2 -0.0
HDL Cholesterol 0.4 0.7 1.4 -0.8 -1.2 -1.0 -0.2 -1.1 -0.9 -0.5 -0.4
LDL Cholesterol 1.8 2.8 8.0 2.8 0.6 0.4 1.6 1.0 2.3 2.3 0.1
Lupus 1.0 1.4 5.0 1.2 -1.5 -2.2 -0.1 0.4 0.1 0.3 -1.6
Neuroticism (2016) 0.6 0.9 2.6 -1.2 0.4 0.8 -1.6 -0.8 -0.8 -0.8 -0.5
Primary Biliary Cirrhosis 2.3 3.3 7.7 -2.3 -1.5 -0.8 -1.4 0.0 -2.5 -2.8 -1.5
Rheumatoid Arthritis 0.3 0.4 1.1 -0.9 0.0 0.0 -0.2 1.0 -0.8 -0.9 -0.1
Schizophrenia (2014) 0.6 1.3 4.0 -0.3 2.0 2.0 -0.5 -1.2 -0.2 -0.1 0.7
Triglycerides 0.8 1.3 5.8 0.3 2.4 1.6 0.4 0.4 -0.3 -0.5 1.1
Type 2 Diabetes (T2D) (2012) 0.7 0.8 2.9 0.9 0.2 0.2 0.4 0.4 1.7 1.4 -0.6
Ulcerative Colitis 0.1 0.2 0.5 -0.6 0.3 0.5 -0.7 0.3 -0.4 0.2 0.0
Blood Eosinophil Count 0.4 3.2 7.8 -2.5 -0.3 -0.9 -1.7 0.7 -2.3 -2.8 -1.6
Blood Platelet Count 0.4 4.2 11.3 3.1 -0.6 -0.9 1.0 0.7 3.4 3.1 -0.5
Blood Red Count 0.1 0.7 2.6 0.7 -0.4 -0.4 -0.1 1.0 -0.2 0.9 -1.6
Blood White Count 0.4 2.7 7.6 0.8 -2.2 -2.3 2.8 -0.3 0.8 0.7 -1.4
Heel T-Score 0.2 1.5 3.8 1.4 0.0 0.3 0.8 1.6 1.3 1.0 2.0
BMI 0.1 0.8 3.8 -0.2 0.8 0.7 -0.9 1.9 -0.3 -0.0 -0.0
Height 0.1 1.5 8.5 -0.4 -0.3 -0.4 -0.5 -1.6 -0.5 -0.4 -2.9
Waist Hip Ratio (WHR) 0.3 1.3 4.5 -1.5 0.8 1.0 -1.1 -0.4 -2.1 -0.8 -0.7
Systolic Blood Pressure 1.1 5.7 20.4 0.4 -4.5 -4.1 0.7 0.2 0.8 0.7 -2.6
Smoking Status 0.1 0.3 0.8 -0.2 0.7 0.4 0.1 0.9 -0.7 -0.5 -0.8
Allergy or Eczema 0.1 0.3 1.3 -0.2 0.8 0.8 0.1 -0.1 0.0 -0.2 1.1
Cardiovascular Disease 1.0 3.2 7.3 -0.3 -2.1 -2.4 -1.1 2.7 -1.0 -0.6 -2.3
Hypothyroidism (self reported) 3.8 8.6 16.2 -4.0 -2.0 -1.4 -2.7 -2.2 -3.9 -3.3 -2.9
Respiratory disease 0.3 0.6 1.9 0.6 -1.0 -0.2 -0.2 -1.4 0.2 0.4 -1.1
Type 2 Diabetes (T2D) (2018) 1.6 3.0 8.2 -1.0 0.4 1.4 -2.6 -2.2 -0.7 -0.4 -2.9
Lung FEV1/FVC ratio 0.2 1.2 4.0 1.3 0.3 -0.0 1.8 2.0 0.1 0.6 -0.0
Lung FVC 0.1 0.5 2.4 0.8 0.5 -0.6 0.1 0.2 0.3 -0.1 1.6
Neuroticism 0.7 1.7 7.2 -0.7 -1.6 -1.7 -0.2 -0.5 -0.2 -0.4 -2.7
Chronotype (morning person) 0.1 0.2 0.6 0.1 -0.5 -0.8 0.1 0.8 -0.4 -0.4 0.2
Hair Pigment 0.4 11.2 26.8 -5.1 -0.1 -0.7 -3.7 -0.3 -4.2 -5.2 -2.2
Tanning 0.0 0.5 1.3 0.8 0.0 0.2 0.0 -0.4 1.1 1.0 1.1
Hand grip strength (left) 0.5 1.4 3.6 0.3 1.2 1.1 1.4 -0.4 1.4 0.7 1.9
Number of treatments/medications taken 1.5 2.8 6.2 -1.5 -1.9 -1.9 -1.0 0.1 -2.1 -1.2 -2.5
Average weekly spirits intake 1.2 1.5 2.7 -0.7 1.5 1.6 -0.3 0.7 -1.6 -1.6 0.7
Sensitivity / hurt feelings 0.9 1.5 4.0 -0.3 -1.7 -1.3 -0.7 -0.7 -1.1 -0.7 -2.0
Frequency of depressed mood in last 2 weeks 0.5 0.7 2.3 -1.3 0.4 0.9 -1.5 -0.2 -0.3 -0.7 -0.4
Hearing difficulty/problems: Yes 0.6 0.9 5.4 -0.4 -0.6 -0.3 -1.2 -0.2 -0.2 -0.2 -2.3
Relative age of first facial hair 0.9 1.9 7.3 1.6 -0.4 -1.6 2.7 1.0 1.0 0.9 0.0
Other serious medical condition/disability diagnosed by doctor 0.5 0.6 1.8 -0.6 -0.2 -0.1 -0.5 0.1 -1.1 -1.3 -1.2
Ever used hormone-replacement therapy (HRT) 0.6 0.8 3.1 0.1 -1.2 -1.0 1.8 -0.4 -0.3 -0.2 -0.5
Ever had hysterectomy (womb removed) 0.2 0.2 0.6 0.2 0.1 0.1 -0.7 0.8 0.6 -0.0 0.0
Systolic blood pressure, automated reading 0.9 2.6 9.1 -0.3 -3.0 -2.8 0.4 0.7 -0.4 0.0 -1.6
Eye problems/disorders: Diabetes related eye disease 0.7 0.8 1.6 0.7 -1.3 -1.2 0.4 -0.2 1.0 0.6 -1.1
Angina 0.8 1.0 1.6 1.2 -0.5 -0.3 0.9 -1.3 1.2 1.2 -1.0
Medication for hormone replacement therapy 0.9 1.0 2.2 -0.7 -0.8 -0.4 0.4 -1.5 -1.4 -1.3 0.6
Vitamin and mineral supplements 0.8 1.0 2.6 -0.4 -1.1 -1.6 0.7 1.0 -0.8 0.3 -1.5
Supplements: Zinc 0.8 0.9 3.4 -0.4 1.1 1.1 -1.9 -0.6 -0.3 -0.8 -0.3
Medication: Co-codamol 0.8 0.9 3.2 1.2 -0.1 -0.0 1.8 -1.4 0.5 0.6 0.4
Medication: Metformin 1.4 1.9 11.0 0.2 -0.5 0.0 -1.3 -1.1 0.4 1.0 -3.3
Diabetes (father) 0.5 0.6 2.0 -0.6 -0.0 0.0 -1.4 0.5 0.3 -0.1 -1.4
Diabetes (mother) 1.2 1.5 7.1 -1.0 -0.4 0.3 -1.5 -0.9 0.3 0.4 -2.7
Severe depression (siblings) 0.2 0.2 0.4 -0.6 0.1 0.6 -0.5 0.1 -0.2 0.1 0.6
Pack years adult smoking proportion 1.0 1.5 3.7 -0.8 -1.9 -1.8 -0.2 -0.7 0.3 -0.3 -1.8
Impedance of leg (right) 0.2 0.9 4.3 -0.1 -0.1 0.3 1.1 1.0 0.6 -0.3 2.1
Leg fat-free mass (left) 0.1 0.3 1.3 -0.3 0.4 0.2 -0.0 -0.2 -0.8 -0.2 -1.1
Trunk fat percentage 0.1 0.5 1.5 -0.5 0.1 0.3 -1.1 1.2 -0.2 -0.2 -1.0
Hand grip strength (right) 0.3 0.8 3.5 0.3 0.8 0.6 1.0 -0.2 0.8 0.0 1.9
Townsend deprivation index at recruitment 1.5 2.1 5.9 1.4 -2.4 -2.4 0.5 -0.1 1.1 1.4 -0.2
Current tobacco smoking 1.9 3.1 7.2 2.7 1.1 0.9 1.8 0.8 2.0 1.8 2.2
Average weekly fortified wine intake 1.6 1.9 4.3 -1.5 1.0 1.1 -1.7 -1.0 -1.2 -2.1 0.9
Maternal smoking around birth 0.6 0.9 2.7 1.4 -0.7 -1.0 0.5 1.6 0.4 0.8 0.5
Fed-up feelings 0.6 1.0 2.0 -1.4 0.4 0.3 -0.6 -1.1 -1.0 -1.4 -1.3
Frequency of unenthusiasm / disinterest in last 2 weeks 0.5 0.6 1.8 0.5 0.7 0.6 -0.2 0.6 1.4 1.3 0.1
Relative age voice broke 1.7 2.6 5.7 1.9 1.6 0.5 2.4 1.0 1.9 1.8 0.4
Taking other prescription medications 1.1 1.7 4.3 -0.9 -1.3 -1.1 -1.0 -0.4 -1.9 -0.8 -2.1
Age when periods started (menarche) 0.2 0.4 1.0 0.7 -0.8 -1.0 0.7 -0.3 0.5 0.7 0.2
Bilateral oophorectomy (both ovaries removed) 0.3 0.3 0.8 -0.5 -0.9 -0.7 -0.2 0.7 0.4 0.5 -0.3
Heel bone mineral density (BMD) T-score, automated (left) 0.4 0.9 2.1 0.5 0.6 1.4 -0.2 1.4 0.9 0.8 1.2
Tinnitus: Yes, but not now, but have in the past 0.4 0.4 1.0 -0.6 0.8 0.8 1.0 -0.8 -0.2 -0.3 -0.2
Qualifications: CSEs or equivalent 0.4 0.5 1.5 0.5 -0.6 -0.9 0.6 -0.5 0.6 0.3 1.2
Serious illness, injury or assault to yourself 0.5 0.7 2.2 0.2 1.5 1.3 -0.5 -0.1 0.1 0.9 -0.5
High blood pressure 0.7 2.0 5.6 -0.1 -2.1 -2.4 -0.4 1.6 -0.4 0.1 -1.8
Hayfever, allergic rhinitis or eczema 0.6 1.4 4.3 -0.1 1.8 1.5 1.0 0.2 0.1 -0.3 2.1
Multivitamins +/- minerals 0.9 1.2 4.2 1.4 0.6 0.8 -0.3 -0.6 2.1 0.8 1.0
Stomach or abdominal pain in last month 1.5 1.9 8.1 0.9 1.0 1.1 0.6 0.1 1.7 0.8 2.8
Supplements: Glucosamine 0.7 0.9 5.1 -0.3 -1.3 -0.2 -2.3 -0.2 0.1 -0.5 0.2
Diverticular disease/diverticulitis (self-reported) 2.6 3.1 5.3 2.3 1.7 1.3 0.4 2.1 1.6 1.7 2.3
Medication: Atenolol 0.3 0.4 0.6 -0.6 0.3 0.5 -0.7 -0.7 -0.7 -0.8 -0.3
Medication: Levothyroxine sodium 4.5 7.6 13.4 -3.4 -2.9 -1.9 -2.8 -1.4 -3.7 -2.5 -2.9
Sitting height 0.0 0.3 1.1 -0.2 0.1 0.1 0.5 -1.0 1.0 -0.3 -0.2
Chronic bronchitis/emphysema (father) 1.6 1.9 3.3 -1.8 1.3 1.7 -1.1 0.3 -1.8 -1.7 -0.3
High blood pressure (mother) 0.7 1.0 3.5 -0.2 1.1 1.1 -0.4 0.9 -0.8 -0.7 1.9
Body mass index (BMI) 0.1 0.2 0.7 0.1 0.3 0.4 -0.8 0.5 -0.3 0.1 -0.7
Impedance of leg (left) 0.1 0.5 1.5 0.0 -0.4 -0.2 0.8 1.1 0.8 -0.1 1.2
Leg predicted mass (left) 0.0 0.3 1.1 -0.3 0.4 0.2 0.0 -0.2 -0.8 -0.2 -1.1
Trunk fat mass 0.1 0.5 1.4 -0.6 0.4 0.5 -1.2 0.8 -0.5 -0.4 -1.0
Waist circumference 0.1 0.4 1.0 0.3 0.7 0.8 -0.6 1.0 -0.5 0.1 -0.4
Number of incorrect matches in round 0.4 0.6 2.8 -0.3 -0.5 -0.2 -0.1 -1.7 -0.3 -0.2 1.2
Past tobacco smoking 0.8 1.5 4.0 1.9 0.0 0.1 0.6 0.5 1.4 1.4 2.0
Alcohol usually taken with meals 0.9 1.5 5.5 -0.4 -1.9 -2.4 -0.4 -0.8 -0.6 -0.6 -1.0
Nervous feelings 0.7 1.3 3.0 -0.2 -1.7 -1.4 0.8 -1.3 -0.1 -0.0 -1.6
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.6 2.3 0.4 0.2 0.2 0.8 0.4 1.5 1.0 0.9
Hearing difficulty/problems with background noise 0.9 1.5 3.5 1.6 -0.4 -0.4 0.3 1.2 1.9 1.8 -0.7
Hair/balding pattern: Pattern 2 0.2 0.2 0.9 0.0 -1.0 -0.7 0.2 -0.1 -0.4 0.2 -0.3
Had menopause 0.2 0.3 0.9 0.6 0.4 0.6 0.4 -0.5 -1.0 -0.2 -0.3
Had other major operations 0.7 0.9 3.4 -0.2 1.9 1.3 -0.6 -0.6 -0.8 -0.6 -0.6
Forced vital capacity (FVC) 0.2 0.9 2.4 -0.9 1.5 1.0 -0.3 1.1 -0.2 -0.6 1.1
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.4 1.4 0.2 0.4 0.7 -0.2 0.8 0.6 0.6 1.2
Ever unenthusiastic/disinterested for a whole week 0.4 0.5 1.6 0.1 -0.3 -1.0 0.7 -1.2 0.3 0.2 -1.1
Qualifications: None of the above 0.9 1.9 4.4 1.6 -1.9 -2.1 1.4 0.2 0.3 0.8 -1.3
Financial difficulties in last 2 years 0.5 0.6 1.7 0.8 -1.3 -1.3 0.3 0.9 -0.3 0.1 0.2
Mouth/teeth dental problems 0.4 0.5 1.1 -1.1 0.5 0.9 -0.9 0.3 -0.6 -1.0 0.1
Heart attack 0.5 0.6 1.4 -0.6 1.2 0.8 -0.6 -0.1 -1.2 -0.8 -0.1
Allergy 0.4 0.9 2.4 -0.1 -1.6 -1.5 -0.8 0.4 -0.2 -0.2 -1.4
Pain all over the body in last month 0.6 0.6 2.8 0.6 -0.0 -0.3 -0.4 1.1 0.0 0.6 -1.7
Diabetes (self-reported) 1.7 2.6 11.3 -1.3 0.5 1.3 -2.0 -1.3 -0.2 -0.2 -3.4
Hayfever/allergic rhinitis (self-reported) 0.3 0.3 1.3 -1.1 -0.1 0.2 -0.5 -0.1 -0.4 -0.7 0.6
Medication: Ramipril 0.9 1.2 2.5 1.6 -0.1 -0.5 1.5 -0.8 1.4 1.4 -0.4
Medication: Simvastatin 0.8 1.2 5.1 0.6 -1.2 -1.1 0.8 0.2 -0.2 0.7 -2.2
Fluid intelligence score 0.8 1.6 3.3 0.8 -0.6 -1.1 1.4 -0.4 1.7 1.8 -1.5
Illnesses of siblings 0.5 0.7 1.5 -0.4 1.2 0.8 1.1 0.3 0.6 -0.3 1.2
Neuroticism score 0.5 1.1 4.7 -1.0 -0.8 -0.7 -0.4 -0.7 -0.7 -0.9 -2.2
Weight 0.1 0.3 0.9 0.0 0.6 0.6 -0.5 0.5 -0.4 -0.1 -0.9
Impedance of arm (right) 0.1 0.3 1.2 -0.8 -0.3 -0.3 0.1 0.3 -0.0 -0.3 1.1
Arm fat percentage (right) 0.1 0.5 2.1 -0.6 0.3 0.4 -1.4 0.6 -0.6 -0.3 -0.5
Trunk fat-free mass 0.1 0.3 0.8 0.4 0.7 0.5 0.2 -0.9 -0.4 0.0 -0.6
Hip circumference 0.1 0.6 1.5 1.2 0.6 0.4 0.5 1.1 0.6 0.7 -0.4
Time employed in main current job 2.4 2.8 5.1 -1.8 0.9 1.8 -2.3 -2.2 -1.8 -1.4 0.0
Alcohol intake versus 10 years previously 2.4 3.6 7.7 1.9 -1.6 -1.5 2.8 1.6 2.3 2.1 0.3
Father’s age at death 0.5 0.7 1.9 -1.4 -0.4 -0.5 0.1 -0.2 -1.3 -1.3 -0.3
Worrier / anxious feelings 0.4 0.7 1.9 -1.2 -0.6 -0.7 -0.5 -0.2 -0.5 -1.0 -1.4
Frequency of tiredness / lethargy in last 2 weeks 0.6 1.0 3.2 -0.7 1.0 1.8 -1.8 0.3 -0.1 -0.0 0.2
Falls in the last year 1.2 1.7 4.9 -0.1 -2.1 -1.7 0.1 0.7 -0.2 -0.7 -2.2
Hair/balding pattern: Pattern 3 1.0 1.4 4.2 2.1 0.2 0.5 1.3 -0.1 1.5 1.5 0.8
Number of live births 1.8 2.5 5.1 2.2 0.6 0.5 2.3 0.5 1.0 1.9 2.2
Forced expiratory volume in 1-second (FEV1) 0.2 0.5 2.2 -0.1 1.0 0.3 0.6 1.5 0.3 0.1 0.7
Pulse rate 0.6 1.0 2.8 0.2 1.6 1.7 0.8 0.2 1.1 0.6 -0.1
Happiness 0.4 0.5 1.2 -0.6 1.1 1.0 0.8 0.5 -0.5 0.2 -0.3
Noisy workplace 0.8 1.0 2.5 -1.0 1.3 1.4 -0.6 -0.5 -0.5 -1.6 0.4
Qualifications: A levels/AS levels or equivalent 0.2 0.4 0.8 -0.6 -0.6 -0.7 -0.0 0.9 -0.7 -0.6 -0.7
Serious illness, injury or assault of a close relative in last 2 years 0.5 0.6 1.9 0.3 1.1 0.8 -0.1 0.6 -1.4 -0.7 -0.3
Mouth/teeth dental problems: Dentures 1.3 2.2 3.9 1.9 1.6 1.2 1.1 0.2 2.0 1.9 1.1
Asthma 0.2 0.4 1.7 -0.3 -0.6 -0.1 -0.1 -1.3 -0.2 0.1 -0.9
Medication: Ibuprofen (e.g. Nurofen) 0.6 0.8 1.5 -0.8 -1.2 -1.0 -1.1 -1.0 -0.3 -0.7 -0.8
Medication: Cholesterol lowering 0.4 0.6 3.0 0.4 -0.7 -0.8 -0.5 0.8 -0.1 -0.0 -1.7
Depression (self-reported) 1.3 1.6 3.7 -1.6 1.7 1.9 -1.3 0.3 -0.9 -0.8 0.5
Medication: Lansoprazole 0.5 0.5 1.9 -1.4 0.5 1.2 -0.0 -0.0 -0.6 -0.5 -0.2
Prospective memory result 0.5 0.6 1.4 0.5 -0.7 -1.0 1.0 1.2 -0.4 0.2 0.3
Lung cancer (father) 2.2 2.5 6.0 0.3 2.4 2.3 -0.1 2.1 0.3 0.2 2.0
Illnesses of mother 1.0 1.3 3.3 1.0 -1.5 -1.8 1.4 -0.7 0.1 0.4 -1.1
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.3 1.0 -0.4 0.7 0.2 0.6 1.0 0.3 0.0 0.2
Pulse wave Arterial Stiffness index 0.5 0.6 1.8 1.3 -0.0 0.3 1.2 0.7 0.5 0.8 -0.4
Impedance of arm (left) 0.1 0.5 2.2 -0.6 -0.1 -0.1 0.0 1.1 0.3 -0.1 1.5
Arm fat mass (right) 0.0 0.2 0.6 0.1 0.1 0.2 -0.7 0.2 -0.1 0.3 -0.8
Trunk predicted mass 0.1 0.3 0.8 0.5 0.7 0.6 0.3 -0.9 -0.3 0.1 -0.6
Standing height 0.0 0.2 0.5 -0.1 0.7 0.4 0.5 -0.2 -0.1 -0.5 -0.6
Length of working week for main job 0.3 0.3 0.9 -1.0 -0.1 0.3 -0.6 -0.0 0.0 0.2 -1.0
Exposure to tobacco smoke at home 1.9 2.1 4.2 1.8 -1.4 -1.2 1.0 1.0 2.1 1.8 -1.0
Breastfed as a baby 0.5 0.6 1.7 -0.5 1.3 1.3 -0.8 -0.2 -0.5 -0.5 -0.1
Tense / ‘highly strung’ 0.3 0.4 0.8 0.2 -0.4 -0.7 0.9 0.3 0.9 0.6 -0.9
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.2 1.2 -0.1 1.1 0.6 -0.4 0.1 -0.2 0.3 -0.2
Hair/balding pattern: Pattern 4 1.3 3.2 6.9 -2.2 -1.9 -1.6 -1.3 -0.2 -2.6 -1.6 -1.7
Birth weight of first child 0.9 1.6 3.4 -1.3 1.3 1.2 -0.7 -0.6 -1.8 -1.9 -0.5
Peak expiratory flow (PEF) 0.3 0.7 2.4 0.9 -0.2 -0.4 1.0 0.1 1.6 1.0 0.5
Pulse wave reflection index 0.6 0.7 2.6 0.7 -1.5 -1.6 0.1 0.0 -0.0 0.2 -0.3
Ever highly irritable/argumentative for 2 days 0.6 0.7 1.8 0.5 0.9 0.9 1.3 1.0 0.5 0.5 0.8
Loud music exposure frequency 0.4 0.5 1.4 -0.8 0.2 0.1 -0.3 -0.3 -1.2 -0.7 -1.1
Qualifications: O levels/GCSEs or equivalent 0.6 0.9 3.4 -0.3 1.3 1.4 -0.4 0.1 -0.1 -0.3 1.9
Mouth/teeth dental problems: Bleeding gums 0.7 0.9 2.6 -0.5 -1.6 -1.5 -0.3 0.2 -0.9 -0.7 -0.9
Blood clot in the leg (DVT) 0.5 0.7 3.0 -0.7 -0.5 -0.3 0.0 -0.6 -1.0 -0.4 -1.7
Medication: Paracetamol 0.3 0.5 1.2 0.6 0.4 0.4 1.1 0.9 0.9 0.6 0.4
Headache pain in last month 0.8 1.4 3.2 1.8 -1.0 -0.9 1.0 -0.7 1.6 1.5 0.1
Medication for cholesterol, blood pressure or diabetes 0.7 1.1 5.4 -0.4 0.7 0.8 1.0 -1.2 0.1 -0.2 2.3
Glaucoma (self-reported) 1.1 1.3 2.9 0.9 -1.7 -1.4 -0.7 0.1 1.0 1.2 -1.4
Gout (self-reported) 1.4 1.9 12.0 0.4 1.2 0.4 -0.1 3.5 0.8 0.4 0.8
Hypothyroidism/myxoedema (self-reported) 5.4 10.6 20.2 -4.2 -2.7 -1.8 -3.3 -2.1 -4.5 -3.6 -2.9
Medication: Amlodipine 0.3 0.4 1.1 0.6 -0.0 0.5 -1.1 0.4 -0.9 -0.0 0.8
Medication: Ventolin 100micrograms inhaler 0.3 0.4 1.2 -1.1 0.5 0.6 0.2 -0.5 -1.0 -0.3 -0.2
Birth weight 0.7 1.6 4.9 -1.7 0.7 -0.0 0.1 1.4 -2.2 -1.7 0.0
Chronic bronchitis/emphysema (mother) 1.3 1.5 4.3 1.1 2.1 1.6 0.5 1.3 0.0 0.5 1.2
High blood pressure (siblings) 0.3 0.4 1.4 0.0 -0.3 -0.5 -1.2 0.8 -0.6 -0.1 -0.5
Forced vital capacity (FVC), Best measure 0.1 0.5 1.7 -0.6 1.3 0.7 0.1 0.9 0.3 -0.1 0.7
Body fat percentage 0.1 0.5 2.3 -0.3 0.2 0.4 -1.0 1.5 -0.2 -0.0 -0.6
Leg fat percentage (right) 0.1 0.4 1.2 0.2 0.6 1.0 -0.6 1.1 -0.1 0.0 0.5
Arm fat-free mass (right) 0.0 0.2 0.8 0.3 0.6 0.6 -0.1 0.2 -0.2 -0.0 -0.9
Exposure to tobacco smoke outside home 0.4 0.5 1.0 -0.3 -0.8 -0.9 1.0 1.0 0.1 -0.5 0.3
Comparative body size at age 10 0.8 2.3 6.3 -1.7 1.1 1.0 -1.7 0.6 -2.5 -1.9 0.4
Number of full brothers 3.6 4.5 10.0 2.5 0.3 0.3 2.9 0.8 2.2 2.4 3.2
Worry too long after embarrassment 0.2 0.3 2.0 -0.0 -0.3 0.0 -0.4 -0.6 -0.3 -0.0 -1.4
Seen a psychiatrist for nerves, anxiety, tension or depression 1.0 1.3 3.5 0.9 -1.1 -1.5 1.9 -1.2 0.5 0.5 0.7
Wheeze or whistling in the chest in last year 0.1 0.2 0.7 -0.7 -0.7 -0.2 0.0 0.1 -0.8 -0.1 0.3
Number of children fathered 1.0 1.1 2.5 0.9 -1.2 -1.1 0.9 0.3 1.4 1.6 -0.1
Reason for reducing amount of alcohol drunk: Health precaution 0.7 0.9 2.5 0.0 -1.2 -1.6 -1.0 -0.6 0.0 0.4 -1.2
Age at first live birth 1.0 1.7 3.6 -1.4 1.4 1.6 -1.3 0.5 -1.2 -1.9 0.3
Pulse wave peak to peak time 0.7 0.8 2.4 -1.6 0.2 -0.2 -1.3 -0.8 -0.7 -1.2 0.3
Health satisfaction 0.8 1.1 3.1 0.7 0.9 0.8 1.0 1.8 0.4 1.5 -0.2
Shortness of breath walking on level ground 0.5 0.6 3.6 -0.1 0.2 0.4 -0.4 -0.1 -0.7 0.2 -1.9
Qualifications: College or University degree 0.6 1.9 4.1 -1.4 -1.3 -2.0 -1.2 -1.1 -0.7 -1.5 -1.4
Eye problems/disorders: None of the above 1.0 1.2 2.8 -1.3 1.5 1.7 -0.5 -0.7 -0.6 -1.1 0.6
Mouth/teeth dental problems: Loose teeth 0.8 0.9 2.8 -1.7 0.2 -0.1 -1.2 0.3 -0.6 -0.9 -1.3
Emphysema/chronic bronchitis 2.0 2.3 5.8 1.7 0.4 0.8 1.5 0.2 2.1 2.4 1.5
Medication for pain relief, constipation, heartburn 0.2 0.4 2.4 0.2 0.3 0.2 -0.2 0.3 -0.5 -0.1 1.6
Neck or shoulder pain in last month 0.6 0.9 2.7 -1.0 -0.1 0.3 -1.2 -0.5 -1.6 -1.0 -0.8
Medication: Blood pressure 0.6 1.1 2.0 1.4 -0.8 -1.0 0.0 0.9 1.1 1.3 -1.2
Angina (self-reported) 0.7 0.9 1.7 1.3 -0.3 -0.2 1.0 -1.0 1.3 1.2 -0.7
Migraine (self-reported) 0.4 0.6 1.9 -0.6 -1.4 -1.3 -0.2 0.5 0.1 -0.4 -0.2
Medication: Ibuprofen 1.2 1.4 3.1 -1.1 -1.8 -1.5 -1.1 -0.6 -0.8 -1.3 -0.9
Medication: Allopurinol 0.8 1.0 6.6 -0.1 0.3 -0.5 -0.7 2.6 0.5 0.1 -0.9
Medication: Omeprazole 1.6 1.9 7.0 -0.4 0.9 0.4 -1.4 -2.6 -1.5 -1.4 -0.9
Medication: Seretide 50 evohaler 0.6 0.6 1.6 -0.5 1.2 1.2 -0.1 -0.1 0.2 0.5 1.3
Mean time to correctly identify matches 1.2 2.4 4.0 -1.7 0.9 1.8 -2.0 -1.2 -1.6 -1.9 0.6
Heart disease (mother) 0.2 0.3 0.6 0.7 0.6 0.5 -0.5 -0.1 -0.7 -0.2 0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.0 0.1 0.1 -0.4 -0.1 -0.1 0.2 0.1 0.1 0.3 0.3
Whole body fat mass 0.1 0.3 0.9 -0.1 0.2 0.4 -0.8 0.7 -0.2 -0.0 -1.0
Leg fat mass (right) 0.1 0.3 0.5 -0.1 0.5 0.6 -0.7 0.6 -0.5 -0.3 -0.5
Arm predicted mass (right) 0.0 0.2 0.6 0.2 0.6 0.7 0.2 -0.0 -0.4 -0.1 -0.8
Pulse rate, automated reading 0.6 2.1 4.2 0.9 0.2 0.3 1.6 -1.9 1.9 2.1 -1.2
Alcohol intake frequency. 0.4 1.0 2.5 1.2 -0.6 -0.7 0.3 -0.6 1.0 1.2 -1.6
Comparative height size at age 10 0.2 0.9 2.8 0.7 1.7 1.6 -0.3 -0.5 0.6 0.5 -0.8
Number of full sisters 0.4 0.5 1.6 1.2 -0.2 -0.4 -0.4 1.2 0.0 0.7 -0.7
Suffer from ‘nerves’ 0.2 0.4 1.3 -0.0 -0.5 0.3 0.2 -1.2 -0.3 0.8 -0.6
Overall health rating 0.1 0.2 1.0 0.4 -0.3 0.3 1.0 0.2 -0.3 0.6 -0.0
Chest pain or discomfort 0.6 0.8 2.1 0.6 0.6 0.9 0.7 -0.4 1.1 1.5 -1.0
Had major operations 1.7 2.0 4.2 1.7 -2.1 -1.7 0.5 -1.0 1.4 1.5 -0.9
Age at last live birth 0.7 1.1 2.2 -0.4 0.9 1.3 -0.7 -1.5 -0.9 -1.0 1.2
Family relationship satisfaction 3.1 3.8 8.6 2.1 -0.8 -1.3 2.9 0.2 2.6 2.9 0.1
Leg pain on walking 0.3 0.4 1.3 0.2 0.5 1.1 0.2 -1.1 0.0 -0.1 -0.3
Qualifications: NVQ or HND or HNC or equivalent 1.9 2.3 4.5 0.4 2.0 2.1 1.2 0.6 1.5 1.2 2.1
Commuting to job workplace: Car/motor vehicle 0.8 1.0 3.3 -0.6 -0.9 -0.8 1.5 0.1 0.1 0.3 -1.8
Illness, injury, bereavement, stress in last 2 years 0.3 0.3 1.0 -0.9 0.1 0.1 0.1 -0.2 0.1 -1.0 0.8
Medication: Aspirin 2.6 3.5 8.6 2.9 -0.5 -1.0 2.1 1.3 2.3 2.4 -1.0
Supplements: Vitamin C 2.5 3.0 5.5 -2.4 1.4 1.9 -1.5 -1.1 -2.0 -2.2 0.3
Knee pain experienced in last month 0.4 0.6 2.9 -0.1 0.3 1.2 -1.7 0.7 -0.3 -0.2 0.1
Hypertension (Self-reported) 0.9 2.4 7.0 0.3 -2.4 -2.6 -0.3 1.3 -0.7 0.1 -2.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.2 0.3 1.1 -0.0 0.5 1.0 0.6 -0.1 0.5 0.3 0.5
Illnesses of father: Heart disease 0.9 1.2 2.9 -0.1 -1.5 -1.7 0.1 -0.7 1.1 0.5 -1.7
Illnesses of siblings: Diabetes 1.8 2.2 6.4 -0.4 -2.0 -1.4 -1.1 -1.7 -0.5 -0.5 -2.5
Smoking status: Previous 1.5 2.2 6.1 -2.2 0.1 0.1 -1.3 -0.5 -1.5 -1.7 -2.5
Forced expiratory volume in 1-second (FEV1), predicted 1.1 2.2 6.8 0.2 2.6 2.3 1.7 1.2 0.4 0.5 0.9
Whole body fat-free mass 0.0 0.3 1.2 0.2 0.5 0.3 0.2 -0.5 -0.5 -0.0 -1.1
Leg fat-free mass (right) 0.1 0.4 2.6 -0.3 0.3 -0.0 -0.2 -0.2 -0.8 -0.2 -1.6
Arm fat percentage (left) 0.1 0.6 2.3 -0.5 0.6 0.7 -1.5 0.8 -0.5 -0.3 -0.1
Average weekly red wine intake 0.6 0.9 2.4 -1.2 0.5 0.5 -1.0 -0.3 -1.5 -1.2 0.1
Handedness (chirality/laterality): Left-handed 1.1 1.4 2.5 0.9 -1.5 -1.6 1.2 1.1 1.0 1.3 -0.0
Mood swings 0.4 0.7 2.1 -1.3 -0.6 -0.5 -0.7 0.2 -0.3 -0.9 -1.4
Loneliness, isolation 0.5 0.8 2.2 0.9 -0.1 -0.0 0.9 0.4 1.5 0.8 -1.1
Long-standing illness, disability or infirmity 1.5 2.3 14.1 -0.8 -0.8 -1.2 0.5 -0.1 -1.2 -0.1 -3.8
Ever had bowel cancer screening 0.9 1.1 2.3 -0.8 0.2 0.4 -1.5 1.1 -1.5 -1.5 -0.3
Diabetes diagnosed by doctor 1.7 2.7 14.7 -0.9 0.2 0.6 -1.8 -1.5 -0.4 -0.3 -3.8
Ever had stillbirth, spontaneous miscarriage or termination 0.6 0.6 1.4 -0.5 -0.4 -0.8 0.8 -1.2 0.1 -0.5 -1.2
Friendships satisfaction 1.1 1.4 4.0 1.0 0.1 0.2 2.0 -0.8 1.4 1.8 -0.1
Qualifications: nursing, teaching 0.6 1.0 2.8 0.2 1.3 0.9 1.7 0.6 0.4 0.7 1.1
Commuting to job workplace: Walk 1.8 2.0 6.1 2.5 -0.3 -0.2 0.6 -1.2 1.6 1.1 2.0
Eye problems/disorders: Cataract 0.3 0.3 1.0 0.5 -1.0 -0.8 0.1 0.3 -0.6 -0.2 0.4
Mouth/teeth dental problems: Mouth ulcers 2.7 4.2 8.4 2.9 -1.4 -1.5 2.2 -1.4 2.8 2.5 -0.4
Medication for cholesterol 0.9 1.4 3.2 -0.9 1.7 1.8 -1.1 0.9 0.4 -0.3 1.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.1 1.3 2.5 -1.4 0.9 1.2 -0.6 -1.2 -1.6 -1.2 0.6
Back pain experienced in last month 0.2 0.4 1.3 -0.1 -0.4 -0.5 -0.3 -0.7 -1.1 -0.3 -0.7
Mineral and other dietary supplements 0.4 0.5 1.5 -0.9 1.2 0.4 0.9 0.5 0.0 0.5 -0.4
Breast cancer (self-reported) 0.8 1.0 2.1 0.7 0.6 1.5 0.4 1.3 1.0 1.2 0.6
Asthma (self-reported) 0.2 0.5 2.4 -0.3 -0.5 0.0 -0.3 -1.6 -0.3 0.0 -0.8
Osteoporosis (self-reported) 0.8 0.9 2.8 0.8 0.5 0.7 0.7 1.7 0.2 0.0 1.7
Osteoarthritis (self-reported) 0.1 0.2 0.6 0.5 0.6 0.8 -0.1 -0.1 0.1 0.4 -0.0
Medication: Aspirin 1.5 1.9 5.4 2.3 -0.5 -0.9 1.4 0.9 1.5 1.6 -1.2
Medication: Gliclazide 0.9 1.1 7.1 -0.1 -0.2 -0.1 -0.1 -0.3 1.0 0.4 -2.7
Illnesses of father: None of the above (group 1) 0.2 0.3 1.0 1.0 0.3 0.7 0.4 -0.1 -0.5 0.1 0.7
Smoking status: Current 2.1 3.4 7.1 2.7 1.0 0.7 2.2 1.2 1.9 1.9 2.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.3 0.7 0.7 0.4 0.3 0.7 0.5 0.3 0.5 0.8
Whole body water mass 0.1 0.3 1.5 0.1 0.4 0.3 0.1 -0.6 -0.6 -0.1 -1.2
Leg predicted mass (right) 0.1 0.4 2.7 -0.2 0.2 -0.1 -0.0 -0.1 -0.6 -0.0 -1.6
Arm fat mass (left) 0.1 0.2 0.8 0.2 0.5 0.6 -0.9 0.5 -0.0 0.2 -0.4
Number of self-reported non-cancer illnesses 0.8 1.3 3.2 -0.9 -1.2 -1.0 -1.1 0.1 -1.8 -0.8 -1.6
Average weekly champagne plus white wine intake 0.8 1.1 4.4 -0.6 0.6 0.4 -0.0 1.3 -0.9 -1.0 2.1
Miserableness 0.1 0.3 0.8 -0.6 0.1 -0.0 -0.4 -0.4 0.2 -0.7 -0.9
Guilty feelings 0.9 1.3 2.7 -0.8 1.4 1.6 -1.4 0.4 -1.4 -1.0 0.2
Wears glasses or contact lenses 0.9 1.1 2.7 0.8 -1.6 -1.5 0.8 -0.6 1.2 0.6 -0.5
Ever taken oral contraceptive pill 0.2 0.3 0.6 -0.7 -0.4 -0.5 0.6 0.0 0.5 0.4 -0.8
Hearing aid user 0.3 0.3 0.6 0.0 -0.8 -0.7 -0.4 -0.0 0.2 -0.6 -0.8
Mother’s age at death 0.6 0.7 2.9 -0.4 0.3 1.0 -1.1 -1.7 -0.0 -0.4 0.1
Financial situation satisfaction 0.3 0.4 1.3 -0.5 0.3 -0.0 1.1 0.8 -0.7 0.0 -0.5
Tinnitus: Yes, now most or all of the time 1.6 1.9 7.7 1.6 -0.7 -0.5 2.8 -0.0 1.0 1.7 0.1
Commuting to job workplace: Public transport 0.5 0.6 1.8 0.2 1.4 0.9 -0.8 -0.4 -0.3 -0.0 1.1
Eye problems/disorders: Glaucoma 1.2 1.4 3.6 0.4 -1.9 -1.8 -0.9 0.4 0.4 0.5 -1.7
Medication: Blood pressure 0.2 0.5 1.4 0.0 -0.7 -0.8 -0.3 0.3 -1.2 -0.5 -0.9
Pain type(s) experienced in last month: Hip pain 0.1 0.1 0.6 -0.1 0.2 0.2 -0.2 -0.8 -0.0 -0.5 -0.2
Supplements: Fish oil (including cod liver oil) 0.5 0.6 1.9 1.4 -1.3 -0.9 0.2 -0.5 0.3 0.4 0.1
High cholesterol (Self-reported) 0.4 0.8 3.0 1.7 -0.7 -0.5 0.2 1.2 0.7 0.7 -0.1
Medication: Bendroflumethiazide 0.7 1.0 3.2 0.2 -1.8 -1.5 0.4 -0.7 -0.7 0.2 -1.3
Medication: Paracetamol 0.4 0.7 1.6 -1.2 0.2 0.2 -0.5 1.2 -0.6 -1.3 0.0
Medication: Lisinopril 2.2 2.8 8.4 -1.1 -1.2 -1.6 -1.6 1.5 -1.7 -0.9 -2.9
Medication: Atorvastatin 0.1 0.1 0.5 0.5 0.1 0.0 -0.1 0.3 -0.3 -0.3 -0.7
Illnesses of father: High blood pressure 1.2 1.4 4.6 0.2 -1.9 -2.1 0.2 0.6 0.6 0.3 -1.5
Alcohol drinker status: Never 1.1 1.3 5.5 2.3 0.6 0.7 1.1 0.4 0.8 1.4 0.5
Ever smoked 1.2 2.1 5.0 -2.2 0.4 0.3 -1.4 -0.9 -1.7 -2.0 -1.4
Basal metabolic rate 0.0 0.2 1.2 0.2 0.5 0.3 0.1 -0.2 -0.4 0.0 -1.1
Leg fat percentage (left) 0.1 0.3 1.2 0.1 0.4 0.5 -0.8 1.1 -0.1 0.0 -0.1
Arm fat-free mass (left) 0.1 0.4 2.3 0.5 -0.0 -0.1 0.2 -0.4 -0.0 0.3 -1.5
Number of operations (self-reported) 0.6 0.8 2.3 1.5 -0.6 -1.0 0.9 -0.0 1.0 1.1 -0.4
Average weekly beer plus cider intake 0.4 0.6 2.1 -0.1 0.9 1.0 -0.1 1.4 0.2 0.2 0.8
Irritability 0.5 0.8 2.4 -0.7 -0.8 -0.7 -0.7 -0.4 -1.0 -0.6 -1.5
Risk taking 1.7 2.5 6.3 1.8 -1.1 -0.4 2.5 0.6 1.5 1.5 2.0
Ever had prostate specific antigen (PSA) test 0.2 0.3 1.1 -0.1 0.1 -0.5 -0.1 -0.1 -0.7 -1.0 0.6
Fractured/broken bones in last 5 years 0.2 0.2 0.7 -0.2 0.8 0.2 0.2 -0.1 -0.1 -0.5 -0.8
Age started oral contraceptive pill 0.3 0.4 1.2 0.2 -0.1 0.6 1.1 -0.6 -0.5 0.4 1.0
Diastolic blood pressure, automated reading 1.2 3.6 8.1 0.5 -2.6 -2.9 2.4 2.1 0.8 1.2 -1.1
Ever depressed for a whole week 0.4 0.5 1.6 0.1 0.5 0.3 -0.2 -1.3 0.6 0.4 -1.1
Unable to work because of sickness or disability 0.3 0.3 1.5 -0.1 1.2 1.0 0.2 -0.1 -0.3 -0.1 -0.2
Commuting to job workplace: Cycle 1.1 1.3 6.6 -0.4 1.2 1.0 -0.5 0.4 -0.2 -0.8 2.6
Myopia 0.1 0.1 0.2 0.2 -0.1 -0.4 -0.1 -0.4 0.0 0.0 -0.5
Vascular/heart problems diagnosed by doctor 0.5 1.4 4.0 -0.0 1.6 2.0 0.3 -1.2 0.1 -0.3 1.7
Cholesterol lowering medication 1.8 2.7 6.4 2.5 -0.9 -1.1 1.8 0.5 1.5 2.4 -1.2
Medication: Omeprazole (e.g. Zanprol) 1.6 2.0 10.2 -0.3 0.6 0.4 -1.1 -3.2 -1.4 -1.0 -1.0
Pain experienced in last month 0.3 0.4 1.6 -0.4 -0.2 -0.6 1.3 0.9 -0.5 -0.5 -0.1
Supplements: Calcium 0.4 0.5 0.9 -0.7 0.8 0.7 -0.3 -0.6 -0.6 -1.0 -0.6
Basal cell carcinoma (self-reported) 2.5 3.0 6.3 -2.5 1.9 1.6 -1.2 0.9 -1.8 -1.9 1.6
Heart attack/myocardial infarction (self-reported) 0.4 0.5 1.5 -0.8 1.0 0.6 -0.4 -0.1 -1.2 -0.9 -0.2
Deep venous thrombosis (DVT) (self-reported) 0.3 0.4 2.2 -0.4 -0.6 -0.5 0.3 -0.3 -0.7 -0.2 -1.5
Heart disease (siblings) 0.5 0.6 1.7 0.6 -1.3 -0.7 0.3 -1.2 0.2 0.6 -0.5
Alcohol drinker status: Previous 0.4 0.5 1.3 0.8 -0.6 -0.9 -0.5 0.1 0.6 0.7 -1.1
Pack years of smoking 1.4 2.0 5.3 -0.7 -2.3 -2.1 -0.4 -0.9 0.1 -0.4 -2.2
Impedance of whole body 0.1 0.5 1.9 -0.6 -0.4 -0.2 0.4 0.9 0.6 -0.2 1.4
Leg fat mass (left) 0.1 0.3 0.7 -0.0 0.4 0.5 -0.7 0.9 -0.5 -0.2 -0.6
Arm predicted mass (left) 0.1 0.4 2.5 0.4 -0.1 -0.1 0.2 -0.4 -0.1 0.2 -1.6