Hub : Genes

IFIH1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Liver 0.820 0.062 9.7e-06 -0.004 NA 0.001 NA 0.004 0.44 NA 0.30 NA 0.24
2 GTEx Stomach 0.204 0.075 8.1e-04 -0.006 NA -0.006 NA -0.005 0.96 NA 0.97 NA 0.72

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.8 1.3 2.5 -1.6 -0.2
Bipolar Disorder or Schizophrenia 0.3 0.8 1.1 -1.1 -0.7
Depressed Affect (Nagel 2018) 0.2 0.5 0.9 1.0 -0.4
Depression (Nagel 2018) 2.8 4.2 5.9 1.6 -2.4
Intelligence (Savage-Jansen 2018) 1.2 3.8 4.5 -2.1 1.7
Neuroticism (Nagel 2018) 0.3 0.7 1.3 1.1 0.2
Schizophrenia (2018) 0.3 0.6 1.2 0.0 -1.1
Schizophrenia vs Biploar Disorder 0.1 0.1 0.3 -0.5 0.0
Worry (Nagel 2018) 1.0 2.1 3.9 2.0 -0.4
Alzheimer’s Disease (in mother) 1.3 1.6 3.0 -0.4 1.7
Alzheimer’s Disease (in father) 0.2 0.2 0.3 0.5 0.3
Alzheimer’s Disease (including proxy) 1.0 1.4 2.7 0.3 1.7
Crohns Disease (2017) 2.0 4.5 6.1 -2.5 1.7
Irritable Bowel Disease (IBD) 2.6 6.2 11.0 -3.3 1.2
Ulcerative Colitis (UC) 1.3 2.4 4.6 -2.1 0.5
Major Depression (MDD) 1.9 2.3 3.7 1.0 1.9
Reaction Time 0.6 1.2 1.2 1.1 -1.1
Verbal and Numeric Reasoning (VNR) 0.8 1.8 2.7 -1.0 1.6
Breast Cancer 0.0 0.1 0.1 -0.0 -0.3
Ovarian Cancer 0.7 0.9 1.5 0.6 -1.2
Prostate Cancer 0.5 0.7 0.8 0.7 0.9
Age at First Birth 0.3 0.4 0.8 -0.9 0.0
Bipolar Disorder (2011) 0.5 0.4 0.9 0.9 0.0
Body Mass Index (BMI) (2010) 0.4 0.5 0.6 0.7 -0.7
Coronary Artery Disease (CAD) 0.1 0.2 0.3 0.6 0.0
Crohns Disease (2012) 0.8 1.2 2.1 -0.6 1.4
Mean Putamen Volume 0.3 0.4 0.5 0.7 0.4
Fasting Glucose 0.1 0.1 0.2 0.1 -0.4
HbA1C 0.7 0.7 1.4 1.2 0.3
HDL Cholesterol 0.5 0.8 1.4 -1.2 0.3
LDL Cholesterol 0.2 0.4 0.7 0.2 0.8
Lupus 0.2 0.3 0.6 0.8 -0.1
Neuroticism (2016) 0.3 0.5 0.9 1.0 0.0
Primary Biliary Cirrhosis 0.0 0.1 0.1 0.1 0.4
Rheumatoid Arthritis 2.1 2.9 5.7 0.3 2.4
Schizophrenia (2014) 0.5 1.1 1.7 -0.8 -1.3
Triglycerides 0.6 0.9 1.6 0.5 -1.2
Type 2 Diabetes (T2D) (2012) 1.7 2.0 3.8 -1.9 0.4
Ulcerative Colitis 0.7 1.0 1.9 -1.4 0.4
Blood Eosinophil Count 0.7 5.7 11.3 -3.4 -0.3
Blood Platelet Count 0.7 7.6 14.7 -3.8 0.7
Blood Red Count 0.1 0.6 1.2 1.1 0.1
Blood White Count 0.7 5.0 9.0 -3.0 1.0
Heel T-Score 0.1 1.1 1.3 -1.2 -0.9
BMI 0.3 1.6 1.6 1.3 -1.3
Height 0.3 6.6 11.2 3.4 -1.4
Waist Hip Ratio (WHR) 0.4 1.6 2.6 1.6 0.8
Systolic Blood Pressure 0.5 2.7 3.2 -1.8 1.5
Smoking Status 1.1 2.6 4.5 2.1 0.8
Allergy or Eczema 1.3 3.4 5.3 -1.2 2.3
Cardiovascular Disease 0.1 0.3 0.4 0.4 0.6
Hypothyroidism (self reported) 2.8 6.4 10.3 3.2 1.6
Respiratory disease 0.5 1.1 2.0 -1.4 -0.4
Type 2 Diabetes (T2D) (2018) 0.0 0.1 0.1 -0.3 0.0
Lung FEV1/FVC ratio 0.4 2.0 3.2 -0.9 1.8
Lung FVC 0.0 0.2 0.3 -0.2 -0.5
Neuroticism 1.7 4.1 8.1 2.9 -0.1
Chronotype (morning person) 0.3 0.6 1.2 -0.0 1.1
Hair Pigment 0.0 0.1 0.2 -0.0 -0.4
Tanning 0.1 1.4 2.6 0.5 -1.6
Hand grip strength (left) 1.2 3.3 4.8 -1.3 -2.2
Number of treatments/medications taken 1.1 1.9 3.8 0.1 1.9
Average weekly spirits intake 0.1 0.1 0.1 -0.3 -0.3
Sensitivity / hurt feelings 1.7 2.9 4.4 1.2 2.1
Frequency of depressed mood in last 2 weeks 2.0 2.8 3.7 1.4 -1.9
Hearing difficulty/problems: Yes 1.2 1.8 3.0 -0.8 1.7
Relative age of first facial hair 0.6 1.3 2.5 1.6 -0.3
Other serious medical condition/disability diagnosed by doctor 1.1 1.4 2.0 -1.4 0.9
Ever used hormone-replacement therapy (HRT) 0.0 0.1 0.1 0.1 -0.3
Ever had hysterectomy (womb removed) 0.8 0.9 1.5 -0.6 -1.2
Systolic blood pressure, automated reading 1.3 3.7 6.1 -1.1 2.5
Eye problems/disorders: Diabetes related eye disease 1.5 1.6 3.3 0.0 -1.8
Angina 4.3 5.7 11.3 3.4 0.1
Medication for hormone replacement therapy 2.2 2.5 3.2 -1.8 1.3
Vitamin and mineral supplements 0.5 0.7 1.4 1.2 -0.3
Supplements: Zinc 0.1 0.1 0.2 -0.4 -0.2
Medication: Co-codamol 0.0 0.0 0.1 0.3 0.1
Medication: Metformin 0.6 0.8 1.2 -0.7 -1.1
Diabetes (father) 2.9 3.6 6.9 -0.6 2.6
Diabetes (mother) 0.4 0.5 1.0 -1.0 0.1
Severe depression (siblings) 0.1 0.1 0.2 -0.0 0.5
Pack years adult smoking proportion 0.3 0.5 1.0 1.0 0.1
Impedance of leg (right) 0.1 0.3 0.4 0.7 0.4
Leg fat-free mass (left) 0.2 1.3 2.4 1.5 -0.4
Trunk fat percentage 0.1 0.3 0.6 0.8 -0.1
Hand grip strength (right) 0.7 2.0 3.1 -0.9 -1.8
Townsend deprivation index at recruitment 0.5 0.7 1.1 -0.5 1.0
Current tobacco smoking 0.4 0.7 1.4 1.2 0.2
Average weekly fortified wine intake 1.0 1.2 1.6 -1.3 0.9
Maternal smoking around birth 1.2 1.7 3.2 0.5 -1.8
Fed-up feelings 2.6 4.7 9.2 3.0 -0.3
Frequency of unenthusiasm / disinterest in last 2 weeks 1.9 2.5 3.4 1.9 -1.2
Relative age voice broke 1.4 2.1 3.4 1.8 -0.9
Taking other prescription medications 0.8 1.3 2.2 1.5 0.6
Age when periods started (menarche) 1.4 3.3 5.5 2.4 1.0
Bilateral oophorectomy (both ovaries removed) 0.6 0.7 0.8 -0.7 -0.9
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.7 1.4 -1.2 -0.1
Tinnitus: Yes, but not now, but have in the past 0.5 0.6 1.1 0.1 -1.1
Qualifications: CSEs or equivalent 2.4 3.2 6.4 -2.5 0.1
Serious illness, injury or assault to yourself 0.3 0.3 0.6 0.8 -0.1
High blood pressure 0.4 1.1 1.4 -0.9 1.2
Hayfever, allergic rhinitis or eczema 2.4 5.3 6.1 -2.1 2.5
Multivitamins +/- minerals 3.1 3.9 7.9 -2.8 0.1
Stomach or abdominal pain in last month 0.9 1.1 2.1 1.5 -0.3
Supplements: Glucosamine 0.6 0.8 1.0 -1.0 0.8
Diverticular disease/diverticulitis (self-reported) 0.8 0.9 1.7 -1.3 -0.3
Medication: Atenolol 0.2 0.2 0.4 0.6 -0.3
Medication: Levothyroxine sodium 2.4 4.0 4.5 2.1 1.9
Sitting height 0.4 2.6 5.0 2.2 -0.5
Chronic bronchitis/emphysema (father) 0.4 0.4 0.5 -0.6 0.7
High blood pressure (mother) 2.2 3.1 4.1 -1.4 2.0
Body mass index (BMI) 0.0 0.1 0.1 0.3 -0.4
Impedance of leg (left) 0.1 0.3 0.5 0.1 0.7
Leg predicted mass (left) 0.2 1.3 2.4 1.6 -0.4
Trunk fat mass 0.2 0.7 1.3 1.1 -0.1
Waist circumference 0.1 0.4 0.5 0.6 -0.7
Number of incorrect matches in round 0.6 0.9 1.8 -0.3 1.3
Past tobacco smoking 1.0 1.9 2.9 -1.7 -1.0
Alcohol usually taken with meals 0.7 1.1 1.1 1.0 -1.1
Nervous feelings 0.6 1.1 1.3 1.1 -0.9
Frequency of tenseness / restlessness in last 2 weeks 1.5 2.3 2.5 1.6 -1.4
Hearing difficulty/problems with background noise 0.0 0.0 0.0 0.2 0.1
Hair/balding pattern: Pattern 2 0.5 0.6 1.0 1.0 -0.5
Had menopause 0.6 0.7 1.3 -1.1 0.3
Had other major operations 0.7 0.8 1.6 0.2 1.3
Forced vital capacity (FVC) 0.1 0.4 0.4 0.6 -0.6
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.5 0.9 -0.9 0.2
Ever unenthusiastic/disinterested for a whole week 0.0 0.0 0.0 -0.0 0.1
Qualifications: None of the above 0.2 0.5 0.8 0.5 0.9
Financial difficulties in last 2 years 0.3 0.4 0.9 -0.9 -0.1
Mouth/teeth dental problems 0.9 1.4 2.8 -0.2 -1.7
Heart attack 3.3 4.3 8.5 2.9 -0.2
Allergy 2.5 5.9 6.0 2.4 -2.5
Pain all over the body in last month 0.0 0.1 0.1 0.1 0.3
Diabetes (self-reported) 0.2 0.3 0.3 -0.6 -0.5
Hayfever/allergic rhinitis (self-reported) 1.1 1.5 2.9 -0.2 -1.7
Medication: Ramipril 0.4 0.6 1.1 1.1 0.1
Medication: Simvastatin 0.0 0.0 0.0 -0.2 -0.2
Fluid intelligence score 0.1 0.3 0.5 -0.7 0.4
Illnesses of siblings 1.3 1.8 3.3 0.5 -1.8
Neuroticism score 1.6 3.3 6.1 2.5 0.7
Weight 0.2 0.9 1.8 1.4 -0.2
Impedance of arm (right) 0.0 0.0 0.0 -0.1 0.1
Arm fat percentage (right) 0.0 0.1 0.1 -0.2 -0.3
Trunk fat-free mass 0.2 1.1 2.2 1.5 -0.0
Hip circumference 0.1 0.5 1.0 -0.1 -1.0
Time employed in main current job 0.7 0.9 1.5 0.5 -1.2
Alcohol intake versus 10 years previously 0.6 0.9 1.3 0.8 1.1
Father’s age at death 0.1 0.1 0.2 0.3 0.4
Worrier / anxious feelings 2.2 4.2 5.8 2.4 1.6
Frequency of tiredness / lethargy in last 2 weeks 1.5 2.5 3.1 1.4 -1.8
Falls in the last year 0.3 0.4 0.8 0.9 -0.1
Hair/balding pattern: Pattern 3 0.1 0.1 0.2 -0.5 0.1
Number of live births 1.6 2.3 4.2 0.6 2.0
Forced expiratory volume in 1-second (FEV1) 0.0 0.0 0.0 -0.1 -0.2
Pulse rate 1.3 2.1 4.1 -2.0 0.3
Happiness 0.7 0.9 1.5 1.2 -0.5
Noisy workplace 0.2 0.3 0.5 0.2 -0.7
Qualifications: A levels/AS levels or equivalent 0.3 0.6 1.2 0.1 1.1
Serious illness, injury or assault of a close relative in last 2 years 2.1 2.5 2.9 -1.7 1.4
Mouth/teeth dental problems: Dentures 1.2 2.0 3.9 -0.2 2.0
Asthma 0.1 0.3 0.3 -0.5 -0.6
Medication: Ibuprofen (e.g. Nurofen) 0.9 1.1 2.2 0.2 1.5
Medication: Cholesterol lowering 0.1 0.2 0.4 0.6 -0.0
Depression (self-reported) 2.6 3.1 4.6 2.1 -1.2
Medication: Lansoprazole 0.1 0.2 0.3 0.6 0.0
Prospective memory result 2.1 2.6 5.0 2.2 -0.5
Lung cancer (father) 0.3 0.3 0.3 -0.5 0.6
Illnesses of mother 0.1 0.1 0.1 0.4 0.2
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.3 0.4 -0.6 0.4
Pulse wave Arterial Stiffness index 1.3 1.6 3.1 1.8 0.1
Impedance of arm (left) 0.0 0.2 0.3 -0.2 0.6
Arm fat mass (right) 0.1 0.4 0.4 0.6 -0.5
Trunk predicted mass 0.2 0.9 1.8 1.3 -0.0
Standing height 0.4 3.5 7.0 2.6 -0.1
Length of working week for main job 2.2 2.5 3.3 1.3 -1.8
Exposure to tobacco smoke at home 1.7 1.9 2.2 1.2 -1.5
Breastfed as a baby 1.4 1.7 2.0 -1.4 1.2
Tense / ‘highly strung’ 1.4 2.2 2.9 1.2 1.7
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.4 0.4 0.6 0.6
Hair/balding pattern: Pattern 4 0.1 0.3 0.5 -0.7 -0.3
Birth weight of first child 0.8 1.4 1.6 1.2 -1.1
Peak expiratory flow (PEF) 0.3 0.6 0.9 -0.6 -1.0
Pulse wave reflection index 4.3 5.3 6.2 2.5 -2.1
Ever highly irritable/argumentative for 2 days 0.7 0.9 1.0 1.0 0.9
Loud music exposure frequency 0.1 0.1 0.2 -0.1 0.5
Qualifications: O levels/GCSEs or equivalent 0.0 0.0 0.1 -0.1 -0.2
Mouth/teeth dental problems: Bleeding gums 0.8 1.1 1.8 1.4 0.5
Blood clot in the leg (DVT) 0.4 0.5 1.0 -0.2 1.0
Medication: Paracetamol 0.1 0.1 0.2 -0.2 0.4
Headache pain in last month 0.4 0.6 1.1 1.0 -0.4
Medication for cholesterol, blood pressure or diabetes 1.0 1.6 2.7 -1.6 0.7
Glaucoma (self-reported) 0.2 0.2 0.4 -0.6 -0.3
Gout (self-reported) 0.0 0.1 0.1 -0.3 -0.1
Hypothyroidism/myxoedema (self-reported) 1.9 3.7 4.9 2.2 1.6
Medication: Amlodipine 0.3 0.4 0.7 -0.4 0.8
Medication: Ventolin 100micrograms inhaler 3.0 3.9 6.5 1.1 -2.6
Birth weight 0.1 0.2 0.2 0.5 0.3
Chronic bronchitis/emphysema (mother) 0.9 1.1 1.7 0.7 -1.3
High blood pressure (siblings) 0.6 0.9 1.3 -1.2 0.6
Forced vital capacity (FVC), Best measure 0.0 0.0 0.0 -0.0 0.2
Body fat percentage 0.0 0.1 0.2 0.4 -0.1
Leg fat percentage (right) 0.1 0.3 0.5 0.7 -0.2
Arm fat-free mass (right) 0.2 1.0 2.0 1.4 -0.2
Exposure to tobacco smoke outside home 0.4 0.5 1.0 0.2 1.0
Comparative body size at age 10 0.0 0.0 0.1 -0.3 0.1
Number of full brothers 0.5 0.6 1.2 1.1 0.1
Worry too long after embarrassment 0.7 1.2 1.8 -0.8 1.4
Seen a psychiatrist for nerves, anxiety, tension or depression 1.1 1.5 2.8 -0.5 1.7
Wheeze or whistling in the chest in last year 0.5 1.0 1.6 -1.2 -0.6
Number of children fathered 0.2 0.3 0.5 -0.3 0.7
Reason for reducing amount of alcohol drunk: Health precaution 0.3 0.4 0.5 -0.6 0.7
Age at first live birth 1.0 1.8 3.5 0.3 -1.9
Pulse wave peak to peak time 1.1 1.2 2.5 -1.6 0.0
Health satisfaction 0.8 1.0 2.0 0.0 1.4
Shortness of breath walking on level ground 0.4 0.4 0.6 0.5 -0.8
Qualifications: College or University degree 1.1 3.4 6.2 2.5 -0.8
Eye problems/disorders: None of the above 2.0 2.3 4.5 2.1 -0.4
Mouth/teeth dental problems: Loose teeth 1.0 1.2 2.4 1.6 -0.2
Emphysema/chronic bronchitis 0.4 0.4 0.5 -0.6 0.7
Medication for pain relief, constipation, heartburn 1.3 2.2 4.4 -0.2 -2.1
Neck or shoulder pain in last month 0.7 1.0 1.5 0.6 1.2
Medication: Blood pressure 1.1 2.0 3.4 1.9 -0.8
Angina (self-reported) 4.0 5.3 10.5 3.2 0.1
Migraine (self-reported) 0.3 0.3 0.4 0.6 -0.6
Medication: Ibuprofen 1.0 1.1 2.1 -0.4 1.4
Medication: Allopurinol 0.3 0.4 0.5 -0.6 0.7
Medication: Omeprazole 0.8 1.0 2.0 -0.1 1.4
Medication: Seretide 50 evohaler 0.3 0.3 0.5 -0.7 -0.4
Mean time to correctly identify matches 0.1 0.2 0.4 0.7 0.1
Heart disease (mother) 1.1 1.4 2.2 1.5 -0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.8 1.0 1.3 1.1 0.8
Whole body fat mass 0.1 0.5 0.9 0.9 -0.3
Leg fat mass (right) 0.1 0.5 0.8 0.9 -0.3
Arm predicted mass (right) 0.2 1.1 2.3 1.5 -0.1
Pulse rate, automated reading 4.0 13.0 25.7 -5.1 0.6
Alcohol intake frequency. 0.0 0.0 0.0 -0.2 0.0
Comparative height size at age 10 0.4 2.1 3.8 0.7 -1.9
Number of full sisters 0.4 0.4 0.5 0.7 0.6
Suffer from ‘nerves’ 0.4 0.6 1.2 1.1 -0.1
Overall health rating 0.9 1.9 2.2 1.2 1.5
Chest pain or discomfort 4.4 6.3 11.9 3.5 -0.9
Had major operations 1.7 2.0 3.7 1.9 0.5
Age at last live birth 0.5 0.8 0.9 0.8 -1.0
Family relationship satisfaction 0.5 0.6 1.2 0.2 -1.1
Leg pain on walking 4.0 5.0 6.5 1.9 2.5
Qualifications: NVQ or HND or HNC or equivalent 1.2 1.4 1.6 -1.3 -1.1
Commuting to job workplace: Car/motor vehicle 0.2 0.3 0.5 -0.2 -0.7
Illness, injury, bereavement, stress in last 2 years 0.4 0.4 0.6 0.5 -0.8
Medication: Aspirin 2.1 2.8 5.6 0.2 2.4
Supplements: Vitamin C 0.4 0.5 0.9 1.0 0.3
Knee pain experienced in last month 0.3 0.4 0.8 0.2 0.9
Hypertension (Self-reported) 0.3 0.9 1.1 -0.8 1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.5 0.9 1.0 -0.3
Illnesses of father: Heart disease 1.9 2.7 5.3 2.3 -0.0
Illnesses of siblings: Diabetes 0.0 0.0 0.1 0.3 0.2
Smoking status: Previous 2.0 2.9 3.9 2.0 1.4
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.8 1.3 -1.1 0.5
Whole body fat-free mass 0.2 1.0 1.9 1.4 -0.1
Leg fat-free mass (right) 0.2 0.9 1.6 1.3 -0.4
Arm fat percentage (left) 0.0 0.0 0.0 -0.0 -0.1
Average weekly red wine intake 0.0 0.1 0.1 -0.2 -0.3
Handedness (chirality/laterality): Left-handed 0.1 0.2 0.3 0.1 -0.6
Mood swings 0.6 1.1 1.7 0.8 1.3
Loneliness, isolation 0.0 0.0 0.0 0.1 -0.2
Long-standing illness, disability or infirmity 1.5 2.3 4.5 0.4 2.1
Ever had bowel cancer screening 2.4 2.9 3.5 -1.5 1.9
Diabetes diagnosed by doctor 0.1 0.1 0.2 0.2 -0.4
Ever had stillbirth, spontaneous miscarriage or termination 1.6 1.7 3.5 -0.1 1.9
Friendships satisfaction 0.0 0.0 0.0 -0.1 -0.0
Qualifications: nursing, teaching 0.5 0.8 1.3 -0.6 1.1
Commuting to job workplace: Walk 0.6 0.6 0.8 0.9 0.6
Eye problems/disorders: Cataract 0.4 0.5 0.8 -0.9 0.4
Mouth/teeth dental problems: Mouth ulcers 0.3 0.5 0.9 -1.0 0.3
Medication for cholesterol 2.4 3.6 5.3 1.3 -2.3
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.2 1.4 2.6 0.4 -1.6
Back pain experienced in last month 1.8 2.6 5.1 0.2 2.3
Mineral and other dietary supplements 0.9 1.2 1.4 1.1 -1.2
Breast cancer (self-reported) 0.1 0.1 0.1 0.3 -0.1
Asthma (self-reported) 0.3 0.5 0.9 -0.4 -0.9
Osteoporosis (self-reported) 0.2 0.2 0.3 0.6 0.3
Osteoarthritis (self-reported) 1.1 1.4 1.9 -0.9 1.4
Medication: Aspirin 2.2 2.8 5.6 0.1 2.4
Medication: Gliclazide 0.1 0.1 0.1 0.3 0.2
Illnesses of father: None of the above (group 1) 3.2 4.0 7.5 -2.7 -0.6
Smoking status: Current 0.3 0.5 1.0 1.0 -0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.3 0.5 -0.7 0.3
Whole body water mass 0.2 0.9 1.8 1.4 -0.1
Leg predicted mass (right) 0.2 0.9 1.7 1.3 -0.4
Arm fat mass (left) 0.1 0.3 0.4 0.7 -0.4
Number of self-reported non-cancer illnesses 0.1 0.1 0.2 -0.4 -0.3
Average weekly champagne plus white wine intake 1.5 2.0 2.2 -1.5 1.4
Miserableness 1.2 2.0 2.8 1.7 -1.1
Guilty feelings 0.0 0.0 0.0 -0.2 0.2
Wears glasses or contact lenses 0.5 0.5 0.9 -0.9 0.5
Ever taken oral contraceptive pill 0.7 0.7 1.4 -0.3 1.2
Hearing aid user 0.2 0.2 0.3 -0.5 0.3
Mother’s age at death 0.4 0.5 1.0 -1.0 0.2
Financial situation satisfaction 0.2 0.3 0.3 -0.6 -0.5
Tinnitus: Yes, now most or all of the time 0.5 0.5 1.1 1.0 0.1
Commuting to job workplace: Public transport 0.4 0.5 1.0 1.0 0.2
Eye problems/disorders: Glaucoma 0.2 0.2 0.3 -0.4 0.5
Medication: Blood pressure 1.8 3.4 5.2 -1.2 2.3
Pain type(s) experienced in last month: Hip pain 2.5 3.2 5.2 2.3 1.1
Supplements: Fish oil (including cod liver oil) 0.8 1.0 1.8 -0.6 1.3
High cholesterol (Self-reported) 1.5 2.7 4.5 2.1 -1.0
Medication: Bendroflumethiazide 2.2 3.3 5.6 -1.0 2.4
Medication: Paracetamol 0.3 0.4 0.4 -0.6 0.7
Medication: Lisinopril 0.8 1.0 1.3 -0.9 1.1
Medication: Atorvastatin 0.2 0.3 0.5 0.3 -0.7
Illnesses of father: High blood pressure 0.1 0.2 0.3 -0.0 0.6
Alcohol drinker status: Never 0.9 1.0 2.0 -1.4 0.1
Ever smoked 0.7 1.2 1.9 0.7 1.4
Basal metabolic rate 0.2 1.1 2.2 1.5 -0.2
Leg fat percentage (left) 0.0 0.1 0.1 0.4 -0.1
Arm fat-free mass (left) 0.2 1.1 1.8 1.3 -0.6
Number of operations (self-reported) 0.1 0.1 0.3 -0.5 0.1
Average weekly beer plus cider intake 0.6 0.8 1.6 -1.3 -0.1
Irritability 1.4 2.4 2.5 1.6 1.5
Risk taking 0.3 0.4 0.6 -0.7 0.6
Ever had prostate specific antigen (PSA) test 0.8 0.9 1.7 1.3 -0.3
Fractured/broken bones in last 5 years 1.2 1.6 2.4 -0.9 -1.6
Age started oral contraceptive pill 1.0 1.2 2.1 -1.4 -0.6
Diastolic blood pressure, automated reading 1.0 3.1 4.6 -2.1 1.2
Ever depressed for a whole week 0.6 0.8 1.1 -0.7 1.0
Unable to work because of sickness or disability 0.9 1.2 2.0 -0.6 1.4
Commuting to job workplace: Cycle 0.8 1.0 2.0 -1.4 -0.2
Myopia 0.7 1.1 1.2 1.1 -1.0
Vascular/heart problems diagnosed by doctor 0.3 0.9 1.9 0.1 -1.4
Cholesterol lowering medication 0.0 0.0 0.1 0.1 0.2
Medication: Omeprazole (e.g. Zanprol) 0.8 1.0 1.9 0.4 1.4
Pain experienced in last month 1.0 1.7 3.1 -0.5 -1.8
Supplements: Calcium 1.4 1.5 2.1 -1.0 1.5
Basal cell carcinoma (self-reported) 0.1 0.1 0.3 -0.5 -0.2
Heart attack/myocardial infarction (self-reported) 3.1 4.1 8.1 2.8 -0.2
Deep venous thrombosis (DVT) (self-reported) 0.2 0.3 0.5 -0.2 0.7
Heart disease (siblings) 1.6 2.0 3.6 -0.7 1.9
Alcohol drinker status: Previous 1.1 1.2 1.8 -1.4 0.8
Pack years of smoking 0.5 0.7 1.4 1.2 0.0
Impedance of whole body 0.0 0.1 0.2 0.1 0.4
Leg fat mass (left) 0.1 0.3 0.5 0.7 -0.2
Arm predicted mass (left) 0.1 0.7 1.3 1.1 -0.3