Hub : Genes

NBN

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0750	0.0310	6.7e-04	0.033	NA	0.035	NA	0.025	9.1e-04	NA	6.5e-04	NA	3.5e-03
2	GTEx	Artery Aorta	0.2350	0.0770	9.1e-04	0.119	NA	0.070	NA	0.123	4.5e-07	NA	1.1e-04	NA	2.8e-07
3	GTEx	Artery Tibial	0.1447	0.0390	9.3e-10	0.091	NA	0.133	NA	0.144	1.3e-07	NA	1.3e-10	NA	2.3e-11
4	GTEx	Muscle Skeletal	0.0541	0.0241	1.1e-03	0.020	NA	0.021	NA	0.018	4.3e-03	NA	3.5e-03	NA	5.6e-03
5	GTEx	Testis	0.3550	0.0780	4.0e-11	0.133	NA	0.201	NA	0.197	1.7e-06	NA	2.6e-09	NA	3.8e-09
6	METSIM	Adipose	0.0865	0.0252	5.9e-11	0.079	0.084	0.091	0.085	0.095	6.0e-12	1.5e-12	1.8e-13	9.2e-13	5.0e-14
7	NTR	Blood	0.0126	0.0067	3.5e-03	0.009	0.007	0.003	0.007	0.009	4.5e-04	1.5e-03	2.3e-02	2.3e-03	3.5e-04
8	YFS	Blood	0.0915	0.0193	0.0e+00	0.133	0.121	0.127	0.129	0.133	3.7e-41	1.4e-37	2.4e-39	5.2e-40	2.5e-41

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.3	0.5	1.7	0.6	-0.1	0.5	0.8	1.3	0.0	-0.7	-0.8
Bipolar Disorder or Schizophrenia	0.7	1.7	3.5	1.4	0.6	1.3	1.4	1.9	0.6	-1.3	-1.5
Depressed Affect (Nagel 2018)	6.1	12.9	17.3	4.2	2.5	3.9	3.4	3.9	3.6	-3.7	-3.4
Depression (Nagel 2018)	3.5	5.3	10.4	2.1	2.3	3.2	1.9	2.2	2.2	-2.5	-1.8
Intelligence (Savage-Jansen 2018)	0.1	0.2	0.6	-0.1	-0.2	-0.7	-0.2	-0.7	-0.3	0.8	0.2
Neuroticism (Nagel 2018)	3.7	8.7	14.2	2.9	2.8	3.8	2.5	3.0	3.2	-2.6	-2.5
Schizophrenia (2018)	0.6	1.3	1.9	1.3	0.9	1.3	1.2	1.4	0.7	-1.1	-1.2
Schizophrenia vs Biploar Disorder	0.5	0.6	2.9	-0.5	-0.2	-0.7	-0.3	-0.8	-0.6	1.7	0.3
Worry (Nagel 2018)	1.2	2.6	6.0	1.3	2.4	2.3	0.7	1.0	2.0	-1.3	-0.8
Alzheimer’s Disease (in mother)	1.0	1.2	3.4	-1.1	-0.8	-1.9	-0.8	-0.9	-1.2	0.8	0.8
Alzheimer’s Disease (in father)	0.2	0.2	0.5	0.7	0.0	-0.4	0.2	0.3	0.3	-0.7	-0.0
Alzheimer’s Disease (including proxy)	0.8	1.2	5.7	-0.5	-0.6	-2.4	-1.0	-1.0	-0.7	0.3	1.0
Crohns Disease (2017)	2.0	4.3	8.8	-3.0	-3.0	-0.2	-1.1	-1.7	-3.0	1.7	1.0
Irritable Bowel Disease (IBD)	1.7	4.1	9.2	-2.2	-3.0	-0.9	-1.2	-1.8	-2.9	1.8	1.2
Ulcerative Colitis (UC)	0.5	0.9	2.2	-0.3	-1.5	-1.1	-0.4	-0.8	-1.3	1.1	0.4
Major Depression (MDD)	1.5	1.8	4.8	1.5	0.3	2.2	1.1	1.0	1.3	-1.3	-1.2
Reaction Time	2.4	4.5	8.1	1.8	1.7	1.8	1.9	2.1	2.8	-2.7	-1.8
Verbal and Numeric Reasoning (VNR)	0.2	0.4	1.2	-0.3	0.0	0.8	1.1	0.6	-0.0	0.1	-1.1
Breast Cancer	0.2	0.5	2.1	-0.3	-1.4	-0.2	0.1	0.6	-1.0	0.4	-0.3
Ovarian Cancer	2.1	2.7	5.6	-2.4	-0.8	-1.1	-1.7	-1.7	-1.7	1.8	1.7
Prostate Cancer	0.2	0.3	1.0	-0.2	-1.0	-0.7	-0.1	-0.3	-0.6	-0.7	0.2
Age at First Birth	2.3	3.3	4.8	-1.7	-1.1	-1.6	-2.0	-2.2	-1.8	1.7	2.1
Bipolar Disorder (2011)	1.8	1.8	4.8	0.2	0.1	0.7	2.0	1.9	0.5	-1.0	-2.2
Body Mass Index (BMI) (2010)	0.5	0.7	1.3	0.6	-1.1	1.1	0.8	0.8	-0.1	-1.1	-0.6
Coronary Artery Disease (CAD)	0.2	0.3	0.8	0.6	-0.8	0.9	0.1	0.5	-0.3	-0.4	-0.0
Crohns Disease (2012)	1.3	2.2	6.4	-2.5	-2.3	0.6	-0.2	-0.9	-1.9	0.9	0.1
Mean Putamen Volume	0.1	0.1	0.4	-0.6	0.2	0.2	-0.2	0.3	-0.4	0.0	0.3
Fasting Glucose	0.1	0.1	0.8	0.9	-0.3	0.1	0.2	0.3	0.1	-0.3	-0.1
HbA1C	0.1	0.2	0.3	-0.2	0.0	-0.6	-0.5	-0.2	-0.4	0.2	0.6
HDL Cholesterol	0.1	0.2	0.5	0.7	0.3	0.7	0.3	0.3	0.5	0.2	-0.2
LDL Cholesterol	0.8	1.3	2.7	-1.3	-1.0	-1.6	-1.0	-0.9	-1.2	0.9	1.0
Lupus	1.0	1.5	2.2	1.3	1.2	1.4	1.2	1.5	1.1	-1.2	-1.1
Neuroticism (2016)	0.8	1.2	2.6	1.4	1.6	1.6	0.1	0.2	1.5	-0.8	0.2
Primary Biliary Cirrhosis	0.1	0.2	0.6	-0.5	-0.6	0.8	-0.2	-0.2	-0.5	0.0	0.3
Rheumatoid Arthritis	1.1	1.5	3.5	-1.9	-1.1	-0.5	-1.0	-1.3	-1.7	0.6	1.1
Schizophrenia (2014)	0.7	1.6	3.0	1.4	0.3	0.9	1.7	1.7	0.5	-0.9	-1.7
Triglycerides	0.2	0.3	1.3	-1.1	0.2	0.2	-0.5	-0.3	-0.3	0.1	0.6
Type 2 Diabetes (T2D) (2012)	0.5	0.6	1.3	-0.4	0.7	-0.6	-1.1	-0.7	-0.0	0.9	1.2
Ulcerative Colitis	0.3	0.4	0.7	0.1	-0.8	-0.8	-0.4	-0.8	-0.8	0.3	0.4
Blood Eosinophil Count	1.1	8.5	16.3	2.0	-0.1	2.4	4.0	4.0	1.4	-2.8	-4.0
Blood Platelet Count	0.1	0.7	1.5	0.8	1.1	0.9	0.5	0.9	1.2	-0.5	-0.5
Blood Red Count	1.2	11.3	16.6	3.8	2.5	3.5	3.2	4.1	2.9	-3.6	-3.1
Blood White Count	0.2	1.7	3.5	0.8	0.1	1.2	1.9	1.7	0.8	-0.8	-1.8
Heel T-Score	0.1	1.0	2.0	-1.2	-0.3	-0.3	-1.4	-1.4	-0.7	0.7	1.3
BMI	0.3	1.6	2.7	-1.3	-1.7	-1.2	-1.1	-1.1	-1.5	1.0	1.0
Height	0.2	2.9	7.7	2.2	0.1	2.0	1.4	1.5	1.0	-2.8	-1.3
Waist Hip Ratio (WHR)	0.7	3.3	4.9	2.1	1.0	1.6	2.0	2.2	1.5	-1.7	-2.0
Systolic Blood Pressure	2.0	10.1	14.1	-3.4	-1.0	-3.0	-3.8	-3.0	-3.0	3.6	3.7
Smoking Status	4.8	11.4	15.8	4.0	-0.1	3.8	3.8	3.7	2.4	-3.6	-3.7
Allergy or Eczema	0.2	0.6	1.6	-0.2	-0.7	-1.3	-0.6	-0.6	-0.9	0.8	0.6
Cardiovascular Disease	2.9	9.7	18.1	-3.0	0.4	-2.2	-4.3	-3.9	-2.1	3.0	4.1
Hypothyroidism (self reported)	0.4	0.9	2.4	-0.4	-1.6	0.2	1.0	0.8	-1.4	-0.1	-1.0
Respiratory disease	0.3	0.6	1.1	0.5	-1.0	0.6	1.0	0.9	-0.0	-0.7	-1.0
Type 2 Diabetes (T2D) (2018)	1.3	2.5	4.0	-1.4	-1.6	-1.6	-1.6	-1.4	-2.0	1.6	1.6
Lung FEV1/FVC ratio	0.1	0.7	1.7	0.5	0.6	-0.3	1.2	1.2	0.3	-0.3	-1.3
Lung FVC	0.3	1.6	4.0	-0.8	1.1	0.1	-1.8	-2.0	-0.1	1.0	1.7
Neuroticism	3.1	7.5	14.3	3.0	2.6	3.8	2.2	2.5	2.7	-2.5	-2.2
Chronotype (morning person)	0.1	0.2	0.8	0.5	-0.3	0.5	0.2	0.9	-0.1	-0.7	-0.2
Hair Pigment	0.1	1.7	3.7	-0.8	-0.7	-0.3	-1.9	-1.8	-1.5	0.4	1.9
Tanning	0.1	0.9	1.5	-0.3	-1.0	-0.6	-0.9	-1.1	-1.2	0.9	1.0
Hand grip strength (left)	0.3	0.8	2.9	0.8	-0.3	1.7	0.7	0.9	-0.0	-1.0	-0.7
Number of treatments/medications taken	0.8	1.5	3.6	-0.5	-0.3	-0.3	-1.7	-1.9	-0.5	1.1	1.8
Average weekly spirits intake	1.1	1.4	3.6	0.9	-1.2	0.9	1.2	1.4	0.1	-1.9	-1.1
Sensitivity / hurt feelings	3.3	5.7	6.8	2.3	1.6	2.5	2.5	2.6	2.5	-2.5	-2.5
Frequency of depressed mood in last 2 weeks	2.5	3.4	6.1	1.7	2.1	2.5	1.4	1.6	1.9	-2.0	-1.4
Hearing difficulty/problems: Yes	0.4	0.6	1.0	0.3	-0.9	-0.9	-0.8	-1.0	0.3	-0.4	0.9
Relative age of first facial hair	0.6	1.3	2.8	0.7	0.0	1.1	1.6	1.7	0.4	-0.9	-1.5
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	3.8	0.3	-2.0	-0.3	0.8	0.3	-1.2	-0.6	-0.7
Ever used hormone-replacement therapy (HRT)	0.6	0.7	2.5	-0.4	-1.0	-1.6	-0.6	-0.9	-0.6	0.7	0.4
Ever had hysterectomy (womb removed)	0.1	0.1	0.3	0.2	-0.2	-0.1	-0.5	-0.5	-0.1	-0.3	0.3
Systolic blood pressure, automated reading	3.0	8.7	11.9	-3.0	-2.7	-3.2	-3.1	-2.8	-3.5	2.2	3.0
Eye problems/disorders: Diabetes related eye disease	1.8	2.0	4.1	1.7	0.0	-0.0	1.8	2.0	0.8	-1.5	-1.7
Angina	3.0	4.0	7.5	2.3	2.5	2.1	1.3	1.6	2.7	-1.7	-1.2
Medication for hormone replacement therapy	0.4	0.5	1.4	1.2	-0.3	0.0	0.8	0.6	0.6	-0.5	-0.7
Vitamin and mineral supplements	0.3	0.3	0.8	-0.9	-0.3	-0.5	0.4	-0.2	-0.7	0.8	-0.5
Supplements: Zinc	1.5	1.6	2.8	1.1	0.3	1.3	1.7	1.6	0.9	-1.3	-1.5
Medication: Co-codamol	0.2	0.2	1.1	-0.3	-0.1	1.1	0.1	0.0	-0.4	0.6	0.0
Medication: Metformin	1.5	2.2	3.8	-1.4	-0.6	-1.5	-1.5	-1.8	-1.4	1.9	1.4
Diabetes (father)	0.5	0.7	1.8	-0.2	0.3	0.3	-1.2	-0.9	-0.2	0.9	1.4
Diabetes (mother)	2.1	2.7	4.7	-0.3	-1.2	-2.2	-1.7	-1.3	-1.8	2.1	1.7
Severe depression (siblings)	0.1	0.2	0.4	0.6	0.6	0.7	-0.0	0.2	0.2	-0.2	0.0
Pack years adult smoking proportion	0.2	0.3	0.8	0.6	0.6	0.9	0.4	0.5	0.8	-0.4	-0.1
Impedance of leg (right)	0.3	1.6	4.4	1.2	2.1	1.0	1.0	1.1	1.7	-0.1	-1.1
Leg fat-free mass (left)	0.1	0.5	1.6	0.6	-1.3	0.5	0.4	0.6	-0.5	-1.1	-0.3
Trunk fat percentage	0.1	0.2	1.0	-0.1	-1.0	-0.4	-0.3	0.2	-0.5	-0.6	0.3
Hand grip strength (right)	0.3	0.7	2.0	0.7	-1.4	1.1	0.6	0.7	-0.8	-0.7	-0.5
Townsend deprivation index at recruitment	0.7	1.0	1.9	1.3	-0.4	0.9	1.1	1.1	0.5	-1.4	-1.0
Current tobacco smoking	2.3	3.8	8.0	1.7	0.2	2.8	2.2	2.2	1.4	-1.7	-2.1
Average weekly fortified wine intake	0.1	0.1	0.3	0.5	0.3	-0.0	0.2	-0.0	0.5	-0.2	-0.3
Maternal smoking around birth	0.7	1.1	2.2	0.5	0.2	1.5	1.4	1.0	0.2	-1.0	-1.5
Fed-up feelings	3.8	7.0	9.7	3.0	1.9	2.6	2.8	3.1	2.7	-2.2	-2.7
Frequency of unenthusiasm / disinterest in last 2 weeks	1.6	2.1	4.1	1.5	1.3	2.0	1.0	1.2	1.5	-1.7	-1.0
Relative age voice broke	0.5	0.7	1.9	0.4	0.6	1.4	0.9	0.9	0.8	-0.8	-0.8
Taking other prescription medications	0.2	0.3	2.2	0.2	0.4	1.5	0.0	0.1	0.2	-0.4	0.0
Age when periods started (menarche)	0.6	1.4	2.9	1.2	0.0	1.2	1.5	1.7	0.6	-0.7	-1.5
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.8	0.6	-0.9	-0.5	0.0	0.1	-0.2	0.1	-0.0
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	0.5	0.1	-0.7	0.3	0.5	0.2	-0.2	-0.1	-0.6
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.1	0.0	0.2	0.2	1.0	0.9	-0.0	-0.1	-1.1
Qualifications: CSEs or equivalent	3.1	4.1	5.3	1.8	2.2	1.7	2.2	2.2	2.3	-1.4	-2.2
Serious illness, injury or assault to yourself	0.9	1.1	1.7	1.3	-0.9	0.4	1.2	1.3	-0.5	-1.2	-1.0
High blood pressure	5.5	15.3	25.4	-3.8	-0.3	-3.9	-5.0	-5.0	-2.6	3.6	4.8
Hayfever, allergic rhinitis or eczema	0.3	0.6	1.8	1.3	-0.7	-0.9	0.8	0.7	-0.0	-0.4	-0.8
Multivitamins +/- minerals	0.4	0.6	1.5	0.7	0.6	1.2	0.0	0.6	0.7	-1.1	0.1
Stomach or abdominal pain in last month	2.5	3.2	4.2	1.7	1.6	2.0	1.7	1.7	1.8	-2.1	-1.6
Supplements: Glucosamine	0.2	0.3	0.9	-0.9	-0.9	-0.4	-0.0	-0.3	-0.7	-0.0	0.1
Diverticular disease/diverticulitis (self-reported)	1.4	1.7	4.4	-1.0	-1.2	-2.1	-0.8	-1.5	-1.2	1.2	0.8
Medication: Atenolol	1.9	2.4	5.6	-1.2	-0.8	-2.4	-1.8	-1.8	-0.8	1.1	1.7
Medication: Levothyroxine sodium	0.2	0.4	1.0	-0.2	-0.5	-0.5	0.9	0.7	-0.4	0.1	-1.0
Sitting height	0.1	0.9	2.1	1.2	-0.1	0.5	1.0	1.0	0.4	-1.5	-0.9
Chronic bronchitis/emphysema (father)	0.1	0.2	0.5	0.6	0.3	0.1	0.4	0.7	0.2	0.2	-0.5
High blood pressure (mother)	0.1	0.1	0.6	0.6	0.2	0.0	0.1	0.3	-0.1	-0.8	-0.1
Body mass index (BMI)	0.2	0.8	2.4	-0.9	-1.6	-0.7	-0.7	-0.5	-1.2	0.3	0.6
Impedance of leg (left)	0.4	2.0	4.4	1.5	2.1	1.1	1.1	1.4	1.9	-0.6	-1.2
Leg predicted mass (left)	0.1	0.5	1.8	0.4	-1.4	0.5	0.2	0.5	-0.7	-0.9	-0.2
Trunk fat mass	0.1	0.4	1.6	0.2	-1.3	-0.2	-0.1	0.4	-0.6	-0.8	0.1
Waist circumference	0.0	0.2	0.7	0.3	-0.9	-0.2	0.1	0.3	-0.1	-0.6	-0.1
Number of incorrect matches in round	2.0	3.3	4.6	1.4	2.0	2.0	1.8	1.8	2.1	-1.3	-1.8
Past tobacco smoking	1.8	3.3	5.4	-2.3	-0.5	-1.4	-1.9	-2.1	-1.4	2.2	2.0
Alcohol usually taken with meals	0.6	1.0	2.9	-0.5	-0.8	-1.7	-1.1	-1.4	-0.4	0.2	1.1
Nervous feelings	0.4	0.7	1.5	0.8	1.2	0.9	0.4	0.6	1.1	-1.0	-0.3
Frequency of tenseness / restlessness in last 2 weeks	3.3	5.1	6.6	2.2	1.8	2.0	2.5	2.3	2.6	-2.0	-2.5
Hearing difficulty/problems with background noise	1.1	1.7	4.2	1.0	-0.1	2.0	1.1	1.3	1.0	-1.9	-1.0
Hair/balding pattern: Pattern 2	1.5	2.0	3.2	1.4	0.4	1.1	1.8	1.7	1.0	-1.6	-1.7
Had menopause	1.6	2.1	4.8	-1.8	-1.4	-2.2	-1.3	-1.4	-1.2	0.6	1.0
Had other major operations	0.8	1.0	3.3	1.8	0.1	1.3	0.7	0.6	0.9	-0.9	-0.6
Forced vital capacity (FVC)	0.4	1.4	4.0	1.6	1.4	2.0	0.3	0.5	1.1	-1.1	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.0	0.1	0.2	-0.1	0.3	0.0	-0.3	0.1	0.1	-0.3
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	1.9	1.2	0.2	1.4	1.0	1.2	0.5	-0.2	-1.0
Qualifications: None of the above	0.2	0.4	0.9	-0.1	-0.3	0.8	0.7	0.9	0.4	-0.8	-0.8
Financial difficulties in last 2 years	1.0	1.3	2.8	1.5	1.0	1.7	0.8	1.0	1.2	-0.9	-0.8
Mouth/teeth dental problems	2.7	4.2	8.1	-2.1	-0.5	0.1	-2.8	-2.3	-1.8	2.1	2.8
Heart attack	0.7	0.9	1.9	-0.7	0.2	0.7	-1.4	-0.9	-0.5	1.0	1.4
Allergy	0.4	1.0	2.4	-1.5	0.8	0.2	-1.1	-1.1	-0.0	1.2	1.0
Pain all over the body in last month	0.2	0.2	0.5	0.7	0.6	0.4	0.3	0.5	0.2	-0.1	-0.4
Diabetes (self-reported)	1.2	1.9	3.1	-1.2	-1.6	-1.8	-1.1	-1.4	-1.5	1.2	1.0
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.7	0.4	0.2	-1.3	-0.4	-0.0	0.0	0.8	0.6
Medication: Ramipril	2.3	3.0	6.4	-0.2	2.2	0.0	-2.5	-1.9	0.8	1.3	2.5
Medication: Simvastatin	2.8	4.2	6.1	-2.4	-0.7	-1.6	-2.5	-2.4	-1.6	1.9	2.4
Fluid intelligence score	0.1	0.3	0.6	-0.8	-0.2	-0.3	0.4	0.0	-0.7	0.6	-0.6
Illnesses of siblings	0.4	0.6	1.5	-1.2	-1.2	-0.3	-0.3	-0.2	-1.2	0.6	0.3
Neuroticism score	4.4	9.1	12.0	3.1	2.3	3.5	2.9	3.0	3.1	-3.1	-2.9
Weight	0.1	0.4	1.8	0.3	-1.4	0.1	0.2	0.5	-0.7	-0.9	-0.2
Impedance of arm (right)	0.3	1.4	2.1	1.2	1.3	0.7	1.1	1.3	1.5	-1.3	-1.0
Arm fat percentage (right)	0.0	0.1	0.4	-0.3	-0.7	-0.2	-0.4	-0.1	-0.2	-0.3	0.4
Trunk fat-free mass	0.1	0.5	0.9	0.9	-1.0	0.5	0.6	0.8	-0.4	-0.8	-0.6
Hip circumference	0.1	0.4	1.9	-0.0	-1.4	-0.6	-0.3	-0.1	-0.9	-0.2	0.4
Time employed in main current job	3.5	4.0	8.1	-2.2	-2.6	-2.2	-1.3	-1.3	-2.8	1.6	1.3
Alcohol intake versus 10 years previously	0.2	0.2	0.7	0.5	0.8	0.4	0.1	0.2	0.8	-0.0	-0.2
Father’s age at death	0.9	1.1	3.5	-0.5	-0.8	-1.9	-0.9	-1.4	-0.8	0.8	0.8
Worrier / anxious feelings	2.1	3.9	6.9	2.4	1.0	2.1	1.9	1.7	1.8	-2.6	-1.9
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	2.3	0.7	0.1	1.5	0.8	0.8	0.6	-1.3	-0.7
Falls in the last year	0.4	0.5	1.8	-0.2	-1.3	-0.1	0.4	0.1	-0.5	-1.3	-0.4
Hair/balding pattern: Pattern 3	0.1	0.1	0.4	-0.6	-0.2	-0.5	-0.2	-0.3	-0.3	0.2	0.1
Number of live births	1.5	2.1	3.7	0.9	1.2	0.7	1.8	1.9	1.0	-1.7	-1.7
Forced expiratory volume in 1-second (FEV1)	0.2	0.5	1.6	0.9	1.3	1.0	-0.1	0.0	0.6	-0.4	0.0
Pulse rate	0.5	0.8	3.5	-0.4	0.4	-1.9	-0.7	-0.6	-0.3	1.1	0.7
Happiness	1.6	1.9	3.5	0.6	1.5	1.9	1.5	1.3	1.1	-1.0	-1.7
Noisy workplace	1.5	1.8	3.9	1.1	-0.5	0.7	1.6	1.3	1.1	-2.0	-1.7
Qualifications: A levels/AS levels or equivalent	0.1	0.3	0.7	0.7	0.8	-0.6	-0.4	-0.5	-0.2	0.7	0.5
Serious illness, injury or assault of a close relative in last 2 years	1.7	1.9	4.5	2.1	0.8	0.5	1.5	1.2	1.7	-1.3	-1.3
Mouth/teeth dental problems: Dentures	0.6	1.1	1.7	0.6	1.0	0.9	1.3	1.0	1.2	-0.8	-1.3
Asthma	0.7	1.3	2.4	1.4	0.0	1.3	1.1	1.3	0.7	-1.6	-1.0
Medication: Ibuprofen (e.g. Nurofen)	3.0	3.8	8.5	1.5	-0.3	1.7	2.9	2.5	1.2	-1.4	-2.7
Medication: Cholesterol lowering	3.1	4.9	8.7	-2.3	0.2	-1.3	-2.9	-2.8	-1.4	2.3	2.9
Depression (self-reported)	0.3	0.3	1.6	0.4	0.1	1.3	-0.6	-0.2	0.3	0.2	0.7
Medication: Lansoprazole	0.2	0.2	0.8	-0.1	-0.2	0.3	-0.4	-0.9	-0.3	-0.1	0.4
Prospective memory result	0.3	0.4	1.4	-1.2	-0.0	0.4	-0.6	0.0	-0.7	0.5	0.7
Lung cancer (father)	0.4	0.5	0.9	-0.6	-0.1	-0.8	-0.8	-0.7	-0.4	1.0	0.8
Illnesses of mother	1.3	1.6	5.6	0.4	1.8	2.4	0.6	0.8	1.4	-0.3	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	1.4	1.2	1.0	0.9	0.5	0.7	0.8	-0.7	-0.5
Pulse wave Arterial Stiffness index	1.7	1.9	4.8	-1.0	-2.2	-1.9	-1.0	-0.6	-1.8	0.5	1.1
Impedance of arm (left)	0.5	2.4	4.0	1.7	1.9	1.1	1.1	1.4	2.0	-1.8	-1.1
Arm fat mass (right)	0.1	0.3	1.4	-0.2	-1.2	-0.5	-0.3	0.0	-0.6	-0.3	0.3
Trunk predicted mass	0.1	0.6	1.0	1.0	-0.9	0.6	0.6	0.9	-0.3	-0.8	-0.6
Standing height	0.4	4.3	7.7	2.8	0.1	1.8	2.1	2.5	1.1	-2.7	-2.0
Length of working week for main job	0.3	0.3	0.4	0.6	0.2	0.5	0.6	0.6	0.5	-0.6	-0.5
Exposure to tobacco smoke at home	0.8	0.9	2.1	1.3	1.4	0.7	0.4	1.1	1.2	-0.3	-0.4
Breastfed as a baby	0.1	0.1	0.3	-0.3	-0.0	-0.6	-0.1	-0.4	-0.3	-0.1	0.2
Tense / ‘highly strung’	1.7	2.7	5.2	1.0	2.1	2.3	1.3	1.2	2.3	-0.9	-1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.7	2.6	7.3	1.7	1.6	2.7	1.0	1.6	1.4	-1.4	-0.9
Hair/balding pattern: Pattern 4	0.2	0.4	1.2	0.5	0.9	1.1	0.2	0.3	0.9	-0.2	-0.1
Birth weight of first child	0.1	0.2	0.4	0.1	-0.4	0.4	0.6	0.5	0.1	-0.4	-0.6
Peak expiratory flow (PEF)	0.1	0.2	0.8	-0.1	0.6	0.9	-0.3	-0.4	-0.1	0.1	0.2
Pulse wave reflection index	2.8	3.5	8.7	-1.9	-3.0	-1.7	-1.4	-1.0	-2.7	0.7	1.3
Ever highly irritable/argumentative for 2 days	1.2	1.4	3.7	-0.1	0.6	1.9	1.4	1.5	0.6	-0.2	-1.6
Loud music exposure frequency	1.3	1.4	2.8	0.9	1.6	1.7	1.0	1.1	1.3	-0.7	-0.9
Qualifications: O levels/GCSEs or equivalent	0.8	1.2	1.7	1.3	1.3	1.2	1.2	1.1	1.1	-0.7	-1.1
Mouth/teeth dental problems: Bleeding gums	0.1	0.2	0.6	0.8	0.2	-0.6	0.3	0.1	0.0	-0.3	-0.3
Blood clot in the leg (DVT)	1.6	2.0	3.4	1.1	1.7	1.4	1.4	1.1	1.9	-1.4	-1.4
Medication: Paracetamol	1.3	2.1	2.7	1.6	0.5	1.5	1.5	1.6	1.5	-1.6	-1.4
Headache pain in last month	1.9	3.3	6.0	1.2	2.5	1.4	1.5	1.7	2.3	-1.9	-1.6
Medication for cholesterol, blood pressure or diabetes	5.3	8.7	15.0	2.7	0.1	2.6	3.9	3.8	2.0	-2.9	-3.8
Glaucoma (self-reported)	0.2	0.3	0.9	0.1	-0.4	-0.0	-0.7	-0.6	-0.5	0.3	0.9
Gout (self-reported)	1.2	1.6	3.3	-1.4	-0.9	-1.4	-1.0	-1.4	-1.2	1.8	0.9
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	2.3	-0.9	-1.5	-0.5	0.8	0.5	-1.3	0.1	-0.9
Medication: Amlodipine	8.6	12.0	25.7	-5.1	-0.9	-2.2	-3.9	-4.1	-3.1	3.2	3.7
Medication: Ventolin 100micrograms inhaler	1.6	2.1	4.4	1.3	0.1	2.1	1.4	1.5	0.9	-1.9	-1.5
Birth weight	0.3	0.7	2.3	-0.9	-0.3	-0.8	-0.6	-1.0	-0.3	1.5	0.5
Chronic bronchitis/emphysema (mother)	1.9	2.2	4.8	1.0	1.0	2.2	1.5	1.8	1.0	-1.5	-1.4
High blood pressure (siblings)	0.6	0.9	1.4	-0.6	-1.0	-1.0	-1.0	-1.2	-1.1	0.5	0.9
Forced vital capacity (FVC), Best measure	0.3	1.0	2.2	1.5	0.6	1.4	0.7	0.8	0.8	-1.1	-0.7
Body fat percentage	0.0	0.1	0.5	-0.1	-0.7	-0.1	-0.2	0.2	-0.3	-0.5	0.2
Leg fat percentage (right)	0.1	0.3	0.8	-0.7	-0.9	-0.4	-0.6	-0.2	-0.5	0.1	0.5
Arm fat-free mass (right)	0.1	0.3	1.0	0.5	-1.0	0.3	0.2	0.4	-0.7	-0.5	-0.2
Exposure to tobacco smoke outside home	0.1	0.1	0.1	0.3	-0.4	-0.3	-0.2	-0.4	0.1	0.1	0.2
Comparative body size at age 10	0.2	0.4	1.1	-1.0	0.6	0.9	-0.0	0.2	0.1	-1.0	0.2
Number of full brothers	1.3	1.7	3.0	1.2	1.0	0.6	1.5	1.7	1.1	-1.3	-1.6
Worry too long after embarrassment	0.1	0.2	0.8	-0.3	-0.4	0.1	0.1	0.3	-0.9	0.6	0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	2.0	1.1	0.6	0.8	0.8	0.8	1.2	-1.4	-0.7
Wheeze or whistling in the chest in last year	3.6	6.5	10.7	2.5	1.1	1.6	3.0	3.2	1.9	-3.3	-2.9
Number of children fathered	1.3	1.4	2.9	1.2	1.6	1.4	0.8	0.6	1.7	-0.9	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	1.3	-0.3	-1.2	-0.9	-0.2	-0.1	-0.8	0.2	0.2
Age at first live birth	1.6	2.8	5.7	-2.2	-0.9	-0.7	-1.6	-2.4	-1.5	1.8	1.5
Pulse wave peak to peak time	1.8	2.1	5.0	1.1	2.2	1.9	1.1	0.8	1.8	-0.5	-1.2
Health satisfaction	0.2	0.3	0.8	-0.5	-0.9	0.0	0.5	0.4	-0.6	0.1	-0.5
Shortness of breath walking on level ground	2.1	2.5	5.9	1.9	-0.2	0.4	1.8	1.9	1.2	-2.4	-1.7
Qualifications: College or University degree	2.2	6.8	12.4	-1.9	-1.3	-2.5	-3.2	-3.5	-2.4	2.0	3.2
Eye problems/disorders: None of the above	1.5	1.8	4.4	0.6	1.2	2.1	1.5	1.3	1.1	-0.5	-1.6
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.4	-0.7	0.2	0.0	0.4	0.4	-0.0	0.1	-0.4
Emphysema/chronic bronchitis	2.4	2.7	5.3	1.4	-1.2	0.9	1.9	2.0	0.1	-2.3	-2.0
Medication for pain relief, constipation, heartburn	0.7	1.1	3.9	-1.0	-1.1	-2.0	-0.7	-0.8	-1.1	0.6	0.5
Neck or shoulder pain in last month	0.4	0.6	1.8	1.0	-0.3	0.3	0.8	0.9	0.5	-1.3	-0.7
Medication: Blood pressure	6.6	11.6	19.9	-2.8	-0.3	-3.2	-4.5	-4.3	-2.2	3.5	4.3
Angina (self-reported)	3.0	3.9	7.3	2.2	2.4	2.1	1.3	1.6	2.7	-1.7	-1.3
Migraine (self-reported)	0.5	0.6	1.2	0.8	-0.0	1.1	0.9	1.1	-0.2	-0.4	-0.9
Medication: Ibuprofen	2.2	2.7	6.2	1.5	-0.5	1.2	2.5	2.0	1.0	-1.0	-2.3
Medication: Allopurinol	0.1	0.2	0.7	-0.4	0.3	-0.5	0.0	-0.0	0.1	0.9	-0.1
Medication: Omeprazole	0.3	0.4	2.4	0.2	0.5	1.5	-0.0	0.3	0.1	-0.0	0.0
Medication: Seretide 50 evohaler	5.2	6.0	7.2	2.5	2.3	2.6	2.2	2.4	2.7	-2.6	-2.1
Mean time to correctly identify matches	1.1	2.0	5.3	1.0	0.9	0.8	1.2	1.3	2.0	-2.3	-1.2
Heart disease (mother)	0.6	0.8	2.8	0.5	-1.7	-1.6	0.1	-0.4	-0.2	-0.6	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.3	-0.1	-0.4	0.1	-0.3	-0.3	-0.2	-0.5	0.3
Whole body fat mass	0.1	0.3	1.6	-0.0	-1.3	-0.2	-0.1	0.3	-0.7	-0.7	0.1
Leg fat mass (right)	0.2	0.6	2.6	-0.6	-1.6	-0.5	-0.5	-0.2	-1.0	-0.0	0.4
Arm predicted mass (right)	0.1	0.3	1.4	0.4	-1.2	0.1	0.0	0.3	-0.8	-0.4	-0.0
Pulse rate, automated reading	1.2	3.9	6.5	-2.3	-0.7	-2.6	-1.8	-2.1	-1.7	2.3	1.7
Alcohol intake frequency.	0.1	0.2	1.6	-1.3	0.1	0.2	0.0	0.2	-0.2	0.2	-0.1
Comparative height size at age 10	0.1	0.3	0.5	0.7	-0.6	0.6	0.4	0.7	-0.4	-0.6	-0.2
Number of full sisters	3.2	3.9	5.3	2.2	1.4	1.6	2.2	2.1	2.3	-1.7	-2.1
Suffer from ‘nerves’	1.6	2.6	5.0	0.7	2.2	1.9	1.5	1.7	1.7	-1.2	-1.6
Overall health rating	0.1	0.3	1.6	0.8	0.0	0.2	0.1	0.1	0.4	-1.3	-0.0
Chest pain or discomfort	0.9	1.2	1.7	1.0	1.1	1.3	1.1	1.2	1.0	-1.1	-1.0
Had major operations	0.9	1.1	2.0	1.4	1.3	1.2	0.4	0.8	1.4	-0.8	-0.4
Age at last live birth	0.1	0.1	0.3	-0.6	0.5	0.5	0.2	-0.2	-0.0	0.2	-0.3
Family relationship satisfaction	5.6	6.9	12.2	2.1	1.1	3.1	3.3	3.0	1.7	-2.2	-3.5
Leg pain on walking	0.4	0.5	1.3	-0.4	-0.5	1.1	0.7	0.8	-0.5	-0.6	-0.7
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	2.4	1.6	0.9	0.8	0.2	0.2	1.5	-0.8	-0.1
Commuting to job workplace: Car/motor vehicle	0.0	0.1	0.1	0.3	-0.4	0.1	0.1	-0.3	0.1	-0.3	-0.1
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	2.8	-1.7	0.6	-0.6	-1.1	-1.1	-0.1	1.1	1.0
Medication: Aspirin	0.9	1.2	3.4	-0.6	0.6	0.4	-1.7	-1.2	-0.2	0.6	1.8
Supplements: Vitamin C	0.4	0.5	1.4	0.8	-1.0	0.7	-0.1	0.1	0.4	-1.2	0.2
Knee pain experienced in last month	1.4	2.2	3.9	2.0	0.5	0.5	1.7	1.5	1.4	-1.7	-1.7
Hypertension (Self-reported)	5.6	15.5	25.7	-3.6	-0.7	-4.0	-5.1	-5.0	-2.8	3.5	4.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.5	0.3	0.7	0.1	-0.3	-0.3	0.2	-0.1	0.2
Illnesses of father: Heart disease	0.2	0.2	0.9	0.4	0.4	0.9	0.4	0.5	0.1	0.3	-0.5
Illnesses of siblings: Diabetes	0.4	0.5	1.2	0.1	1.1	-0.8	-0.7	-0.9	0.4	0.8	0.7
Smoking status: Previous	1.2	1.8	3.4	1.8	0.6	0.7	1.4	1.4	1.1	-1.7	-1.4
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.3	4.9	2.2	-0.4	1.1	1.7	1.8	0.5	-1.5	-1.8
Whole body fat-free mass	0.1	0.5	1.6	0.6	-1.2	0.3	0.4	0.7	-0.6	-0.8	-0.4
Leg fat-free mass (right)	0.1	0.6	2.0	0.6	-1.4	0.5	0.4	0.7	-0.6	-1.2	-0.3
Arm fat percentage (left)	0.0	0.1	0.2	-0.1	-0.5	-0.1	-0.5	-0.2	-0.1	-0.5	0.4
Average weekly red wine intake	0.4	0.7	2.0	-0.9	-0.7	-1.4	-0.3	-0.6	-0.9	0.8	0.3
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.5	-0.9	-1.2	-0.2	-0.6	-0.5	-1.0	0.5	0.6
Mood swings	8.3	15.1	19.8	4.4	2.1	4.4	4.0	4.3	3.5	-4.0	-3.9
Loneliness, isolation	7.6	10.5	14.9	3.7	1.8	2.9	3.3	3.3	3.4	-3.9	-3.1
Long-standing illness, disability or infirmity	0.3	0.5	2.8	0.5	-1.7	0.3	-0.1	-0.2	-1.0	-0.2	0.2
Ever had bowel cancer screening	0.0	0.0	0.1	-0.0	0.1	-0.3	-0.0	-0.3	0.2	-0.0	0.0
Diabetes diagnosed by doctor	0.6	1.1	1.5	-0.8	-1.2	-1.1	-1.0	-1.2	-1.2	0.8	0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	1.0	-0.5	-1.0	0.7	0.2	0.1	-0.7	-0.8	-0.2
Friendships satisfaction	3.8	4.7	7.0	2.4	1.0	2.2	2.6	2.6	1.2	-2.0	-2.6
Qualifications: nursing, teaching	1.4	2.2	4.8	-1.0	0.2	-1.5	-1.8	-2.2	-0.8	1.2	1.9
Commuting to job workplace: Walk	0.2	0.3	0.5	-0.3	-0.7	-0.1	0.6	0.5	-0.7	-0.1	-0.6
Eye problems/disorders: Cataract	3.5	4.0	7.4	-1.2	-0.7	-1.6	-2.7	-2.6	-1.8	1.8	2.7
Mouth/teeth dental problems: Mouth ulcers	10.1	16.1	22.7	4.8	2.8	0.8	4.5	4.5	4.7	-3.7	-4.5
Medication for cholesterol	0.3	0.4	1.1	0.2	-1.0	0.2	0.9	0.8	-0.3	-0.5	-0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.7	3.4	1.3	1.3	1.8	1.1	1.4	1.1	-1.3	-1.0
Back pain experienced in last month	0.7	1.0	1.9	1.0	-0.3	1.1	1.2	1.4	0.4	-0.8	-1.1
Mineral and other dietary supplements	0.5	0.6	1.4	0.2	0.0	0.9	1.1	1.1	0.4	-0.5	-1.2
Breast cancer (self-reported)	0.9	1.1	1.8	1.1	0.7	0.6	1.3	1.1	1.2	-1.0	-1.3
Asthma (self-reported)	0.8	1.5	2.9	1.4	0.1	1.5	1.2	1.4	0.7	-1.7	-1.1
Osteoporosis (self-reported)	0.5	0.7	1.3	-1.0	-0.4	-1.1	-0.8	-0.7	-0.4	0.9	0.9
Osteoarthritis (self-reported)	0.1	0.1	0.4	-0.4	0.0	0.6	-0.1	-0.3	0.2	-0.2	-0.0
Medication: Aspirin	0.8	1.1	3.1	-0.6	0.5	0.4	-1.7	-1.3	-0.2	0.4	1.8
Medication: Gliclazide	0.5	0.6	1.8	-0.7	-0.0	-0.7	-0.6	-0.8	-0.8	1.3	0.5
Illnesses of father: None of the above (group 1)	0.5	0.6	1.5	0.6	0.1	-0.2	1.0	1.1	0.5	-1.2	-0.9
Smoking status: Current	2.5	4.0	7.8	1.9	0.3	2.8	2.2	2.3	1.6	-1.9	-2.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.5	0.5	0.7	0.2	-0.2	-0.2	0.7	-0.3	0.1
Whole body water mass	0.1	0.5	1.3	0.7	-1.1	0.4	0.5	0.7	-0.5	-0.9	-0.4
Leg predicted mass (right)	0.1	0.6	1.9	0.6	-1.4	0.6	0.4	0.7	-0.6	-1.1	-0.3
Arm fat mass (left)	0.1	0.2	1.1	-0.2	-1.1	-0.3	-0.3	0.0	-0.6	-0.5	0.3
Number of self-reported non-cancer illnesses	2.0	3.5	7.2	-1.0	-0.7	-1.7	-2.6	-2.7	-1.1	1.4	2.6
Average weekly champagne plus white wine intake	0.7	0.9	1.9	-0.3	1.3	-0.4	-0.9	-1.4	1.0	0.9	0.9
Miserableness	1.5	2.6	8.2	2.9	0.8	1.3	1.2	1.4	1.5	-1.9	-1.2
Guilty feelings	2.1	3.2	5.1	1.9	1.7	2.1	1.7	1.8	2.3	-0.8	-1.6
Wears glasses or contact lenses	0.8	0.9	3.0	-0.4	-1.1	-1.7	-0.8	-0.9	-0.9	0.1	0.7
Ever taken oral contraceptive pill	0.1	0.1	0.6	0.1	0.5	0.2	0.2	0.2	0.2	0.8	-0.3
Hearing aid user	0.2	0.2	0.7	0.1	0.7	0.8	-0.4	-0.1	0.2	0.1	0.4
Mother’s age at death	2.3	2.8	7.2	-1.4	-0.9	-2.7	-1.8	-1.9	-1.0	1.5	1.7
Financial situation satisfaction	0.7	0.8	1.9	0.1	-0.1	0.9	1.3	1.2	0.3	-0.9	-1.4
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.3	0.0	-0.1	-0.7	-1.0	-1.1	0.0	1.1	1.1
Commuting to job workplace: Public transport	0.2	0.2	0.5	0.6	0.5	-0.5	0.0	0.4	0.4	0.7	-0.1
Eye problems/disorders: Glaucoma	0.2	0.2	0.8	0.5	-0.2	0.3	0.1	0.4	0.3	-0.9	-0.0
Medication: Blood pressure	2.1	4.0	6.5	-2.2	-0.2	-2.0	-2.5	-2.5	-1.3	1.8	2.3
Pain type(s) experienced in last month: Hip pain	0.5	0.6	2.7	-0.2	-1.6	-0.8	0.2	0.2	-1.2	0.3	-0.3
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.6	0.4	0.4	-0.8	-0.7	-0.4	0.1	0.6	0.7
High cholesterol (Self-reported)	2.8	5.0	6.7	-2.5	-0.4	-2.4	-2.6	-2.6	-1.8	2.1	2.5
Medication: Bendroflumethiazide	1.1	1.7	3.2	-1.4	-0.3	-0.9	-1.7	-1.8	-1.1	1.0	1.5
Medication: Paracetamol	0.6	0.9	1.6	1.1	-0.0	0.6	1.0	1.1	0.9	-1.3	-0.9
Medication: Lisinopril	5.7	7.4	11.2	-2.3	-0.6	-2.7	-3.2	-3.3	-2.1	3.1	3.2
Medication: Atorvastatin	0.2	0.3	0.6	-0.8	0.2	-0.4	-0.6	-0.6	-0.4	0.7	0.5
Illnesses of father: High blood pressure	0.8	1.0	4.1	0.5	1.2	2.0	0.7	0.5	0.8	-0.4	-0.8
Alcohol drinker status: Never	0.1	0.2	0.6	-0.8	0.5	0.3	0.0	0.1	0.0	0.5	0.1
Ever smoked	2.5	4.3	6.8	2.6	0.7	2.0	2.1	2.5	1.8	-2.3	-2.1
Basal metabolic rate	0.1	0.5	1.2	0.7	-1.1	0.5	0.5	0.8	-0.5	-0.9	-0.4
Leg fat percentage (left)	0.1	0.2	0.9	-0.5	-0.9	-0.3	-0.5	-0.1	-0.6	-0.1	0.4
Arm fat-free mass (left)	0.1	0.3	1.3	0.1	-1.1	-0.1	-0.1	0.1	-0.9	0.1	0.1
Number of operations (self-reported)	0.3	0.5	1.9	1.4	-0.0	1.1	0.4	0.3	0.3	-0.5	-0.4
Average weekly beer plus cider intake	4.9	7.1	8.7	2.9	2.3	2.9	2.6	3.0	2.9	-1.9	-2.6
Irritability	2.2	3.7	5.2	1.8	0.9	2.0	2.3	2.2	1.9	-1.7	-2.2
Risk taking	1.3	2.0	5.6	2.4	1.4	0.8	0.9	1.1	1.8	-1.2	-0.9
Ever had prostate specific antigen (PSA) test	2.4	2.7	6.7	2.1	2.6	1.4	0.9	1.1	2.1	-1.2	-0.9
Fractured/broken bones in last 5 years	0.2	0.2	0.9	0.9	-0.1	0.6	0.2	0.4	-0.1	-0.7	-0.1
Age started oral contraceptive pill	0.8	1.0	3.1	-1.6	-0.3	-1.8	-0.7	-0.7	-0.7	0.6	0.6
Diastolic blood pressure, automated reading	2.2	6.8	9.4	-2.6	-2.6	-2.7	-2.8	-2.5	-3.1	1.7	2.7
Ever depressed for a whole week	2.4	2.9	4.9	2.2	1.1	2.1	1.3	1.6	1.7	-2.0	-1.4
Unable to work because of sickness or disability	1.4	1.8	6.6	1.0	0.9	2.6	1.1	1.3	0.6	-1.2	-1.0
Commuting to job workplace: Cycle	0.2	0.3	0.8	-0.9	-0.5	-0.5	-0.3	-0.2	-0.9	0.2	0.3
Myopia	1.3	1.8	5.5	-0.7	-0.2	-1.3	-1.3	-1.7	-0.6	2.3	1.3
Vascular/heart problems diagnosed by doctor	4.1	11.3	21.3	3.1	-0.1	3.1	4.6	4.4	1.9	-2.7	-4.5
Cholesterol lowering medication	1.2	1.7	2.7	-1.5	-0.9	-1.6	-1.4	-1.3	-1.3	1.1	1.3
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	3.4	0.4	0.7	1.8	0.1	0.4	0.3	-0.0	-0.1
Pain experienced in last month	1.7	2.8	4.9	-2.2	-0.8	-1.0	-1.8	-1.8	-1.7	1.9	1.8
Supplements: Calcium	4.9	5.4	7.6	-2.6	-1.9	-2.4	-2.4	-2.8	-2.1	1.7	2.5
Basal cell carcinoma (self-reported)	0.3	0.3	0.9	0.9	-0.6	-0.1	0.5	0.6	-0.4	-0.5	-0.5
Heart attack/myocardial infarction (self-reported)	0.6	0.8	1.9	-0.5	0.5	0.7	-1.4	-0.9	-0.2	1.0	1.3
Deep venous thrombosis (DVT) (self-reported)	1.7	2.3	4.0	1.1	1.9	1.4	1.3	1.1	2.0	-1.5	-1.3
Heart disease (siblings)	1.2	1.5	4.9	1.0	2.2	0.9	0.2	0.1	2.2	-0.6	-0.1
Alcohol drinker status: Previous	2.4	2.8	5.4	1.3	0.9	2.3	1.7	1.6	1.6	-1.9	-1.7
Pack years of smoking	0.2	0.3	0.7	0.5	0.7	0.6	0.1	0.2	0.8	-0.2	0.1
Impedance of whole body	0.5	2.7	4.1	1.8	1.9	1.2	1.4	1.6	2.0	-1.4	-1.4
Leg fat mass (left)	0.1	0.4	2.0	-0.3	-1.4	-0.3	-0.4	-0.1	-0.9	-0.2	0.3
Arm predicted mass (left)	0.1	0.3	1.4	0.2	-1.2	-0.1	0.1	0.4	-0.8	-0.2	-0.1