Hub : Genes

RP11-1017G21.6

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1370	0.0490	0.00056	0.036	NA	0.043	NA	0.049	6.2e-04	NA	1.9e-04	NA	6.9e-05
2	GTEx	Artery Aorta	0.1390	0.0500	0.00120	0.056	NA	0.128	NA	0.136	4.9e-04	NA	1.5e-07	NA	6.0e-08
3	GTEx	Brain Cerebellar Hemisphere	0.3840	0.1200	0.00290	-0.010	NA	0.191	NA	-0.006	7.0e-01	NA	1.2e-05	NA	5.1e-01
4	GTEx	Colon Sigmoid	0.2570	0.0780	0.00130	0.171	NA	0.097	NA	0.168	1.2e-06	NA	2.7e-04	NA	1.5e-06
5	GTEx	Esophagus Mucosa	0.1360	0.0540	0.00680	0.040	NA	0.021	NA	0.025	1.1e-03	NA	1.4e-02	NA	8.6e-03
6	GTEx	Nerve Tibial	0.1798	0.0683	0.00220	0.030	NA	0.018	NA	0.032	3.4e-03	NA	1.7e-02	NA	2.3e-03
7	GTEx	Skin Sun Exposed Lower leg	0.1420	0.0440	0.00010	0.093	NA	0.062	NA	0.069	3.7e-08	NA	8.0e-06	NA	2.3e-06
8	METSIM	Adipose	0.0729	0.0269	0.00015	0.050	0.024	0.040	0.031	0.046	4.5e-08	0.00012	9.3e-07	1.5e-05	1.6e-07

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.5	0.8	1.7	1.0	-1.3	0.0	0.8	1.1	0.9	1.0	0.6
Bipolar Disorder or Schizophrenia	0.1	0.2	1.3	0.0	-0.7	1.1	-0.1	0.0	-0.0	0.1	-0.2
Depressed Affect (Nagel 2018)	4.0	8.3	11.8	-3.0	-3.1	-2.3	-2.7	-3.4	-2.9	-2.7	-2.7
Depression (Nagel 2018)	1.0	1.5	2.7	-1.3	-0.6	-0.7	-1.2	-1.6	-1.1	-1.3	-1.5
Intelligence (Savage-Jansen 2018)	0.1	0.2	0.4	-0.2	-0.6	-0.1	0.5	0.6	0.2	0.5	-0.0
Neuroticism (Nagel 2018)	1.2	2.8	3.3	-1.7	-1.7	-1.8	-1.5	-1.8	-1.6	-1.5	-1.7
Schizophrenia (2018)	0.3	0.6	1.6	-0.8	-0.2	1.3	-0.7	-0.9	-0.8	-0.7	-0.7
Schizophrenia vs Biploar Disorder	0.2	0.2	0.5	-0.6	-0.0	0.1	-0.6	-0.6	-0.7	-0.5	-0.4
Worry (Nagel 2018)	0.0	0.1	0.3	0.3	0.2	-0.5	0.3	-0.0	0.3	0.0	-0.1
Alzheimer’s Disease (in mother)	0.3	0.3	0.7	0.8	0.6	-0.4	0.5	0.4	0.6	0.4	0.6
Alzheimer’s Disease (in father)	0.2	0.2	0.7	0.1	0.7	0.8	-0.2	0.3	-0.1	-0.2	-0.0
Alzheimer’s Disease (including proxy)	0.1	0.2	0.9	0.5	0.9	0.0	0.2	0.5	0.3	0.2	0.4
Crohns Disease (2017)	0.2	0.4	0.8	-0.9	-0.8	0.8	-0.5	-0.5	-0.8	-0.4	-0.2
Irritable Bowel Disease (IBD)	0.1	0.2	0.4	-0.6	-0.6	0.5	-0.3	-0.2	-0.5	-0.1	-0.1
Ulcerative Colitis (UC)	0.1	0.1	0.5	-0.4	-0.7	0.1	-0.4	0.0	-0.4	-0.2	-0.3
Major Depression (MDD)	0.5	0.5	2.3	-0.2	-1.5	-1.1	-0.2	-0.3	-0.3	-0.3	-0.8
Reaction Time	0.3	0.6	4.6	0.0	2.1	0.3	-0.1	0.4	-0.2	-0.0	-0.4
Verbal and Numeric Reasoning (VNR)	0.4	1.0	2.2	0.6	-1.0	-0.0	1.1	1.5	1.0	1.2	1.0
Breast Cancer	0.3	0.7	1.2	-1.1	0.6	0.7	-0.8	-1.1	-0.9	-0.8	-0.8
Ovarian Cancer	2.0	2.7	3.3	-1.8	-1.7	1.6	-1.7	-1.5	-1.8	-1.7	-1.4
Prostate Cancer	0.1	0.1	0.4	0.2	0.5	-0.6	0.2	-0.5	0.3	-0.0	-0.2
Age at First Birth	0.6	0.9	1.4	-1.1	-0.8	0.2	-0.9	-1.2	-0.9	-1.0	-0.9
Bipolar Disorder (2011)	0.7	0.7	1.7	0.8	-0.6	-0.2	0.7	1.3	0.8	0.9	0.8
Body Mass Index (BMI) (2010)	0.8	1.2	2.7	-0.9	0.1	-0.2	-1.1	-1.6	-1.1	-1.5	-1.1
Coronary Artery Disease (CAD)	1.0	1.2	2.4	-1.1	-1.6	0.6	-1.0	-1.3	-1.1	-1.0	-0.9
Crohns Disease (2012)	0.3	0.5	1.1	-1.1	-0.3	0.8	-0.7	-0.6	-0.9	-0.5	-0.4
Mean Putamen Volume	0.1	0.1	0.3	0.2	0.3	0.6	0.1	0.4	0.1	-0.2	0.2
Fasting Glucose	1.2	1.5	4.4	0.9	2.1	0.6	1.4	0.9	1.2	1.0	1.1
HbA1C	0.1	0.1	0.2	0.1	-0.5	0.2	0.1	0.5	0.2	0.4	0.1
HDL Cholesterol	0.2	0.3	1.0	0.5	-0.3	-1.0	0.3	0.3	0.4	0.4	0.5
LDL Cholesterol	0.4	0.6	2.2	0.3	0.6	-1.5	0.6	1.0	0.3	0.4	0.5
Lupus	3.0	4.6	6.2	2.3	1.8	2.5	2.3	1.9	2.1	2.1	2.2
Neuroticism (2016)	1.7	2.4	4.1	-1.1	-0.6	-0.0	-2.0	-2.0	-1.6	-1.8	-1.9
Primary Biliary Cirrhosis	1.0	1.5	6.3	-1.3	-2.5	-0.7	-0.8	-0.4	-1.0	-0.9	-0.9
Rheumatoid Arthritis	2.0	2.7	4.0	2.0	-0.0	1.2	1.7	1.9	1.9	1.7	1.8
Schizophrenia (2014)	0.1	0.3	1.9	0.2	0.2	1.4	0.3	0.2	0.2	0.3	0.2
Triglycerides	0.1	0.1	0.5	0.1	0.6	0.7	0.0	0.4	0.0	0.0	0.1
Type 2 Diabetes (T2D) (2012)	0.7	0.9	1.4	-0.9	0.8	-0.1	-1.0	-1.0	-0.9	-1.1	-1.2
Ulcerative Colitis	0.1	0.2	1.0	-0.5	-1.0	-0.1	-0.2	0.1	-0.3	-0.1	-0.4
Blood Eosinophil Count	0.1	0.8	4.8	0.1	-2.2	0.1	0.3	0.8	0.2	0.2	0.7
Blood Platelet Count	0.0	0.5	1.8	0.7	-0.3	1.3	0.1	-1.0	0.2	0.7	-0.2
Blood Red Count	0.4	3.6	7.1	-1.7	0.2	0.3	-2.2	-2.3	-2.0	-2.1	-2.7
Blood White Count	1.2	8.7	16.6	-2.7	-1.6	-1.6	-3.0	-4.1	-3.0	-3.1	-3.5
Heel T-Score	0.2	1.7	2.6	1.4	0.5	1.2	1.4	1.6	1.6	1.3	1.3
BMI	4.1	23.7	42.5	-5.1	-2.4	-0.1	-5.2	-6.5	-5.4	-5.9	-5.0
Height	0.1	1.5	7.1	-1.0	-1.4	2.7	-0.8	-0.2	-0.8	-0.2	-0.5
Waist Hip Ratio (WHR)	0.0	0.1	0.4	0.6	0.1	-0.1	-0.1	-0.5	0.1	-0.1	-0.3
Systolic Blood Pressure	0.1	0.4	0.9	-0.3	-0.8	-0.9	-0.6	-0.8	-0.4	-0.5	-0.7
Smoking Status	0.3	0.7	2.0	1.0	1.4	1.0	0.3	-0.0	0.6	0.4	0.6
Allergy or Eczema	0.2	0.7	1.6	0.9	0.6	-1.3	0.7	0.8	0.8	0.5	0.8
Cardiovascular Disease	0.2	0.7	1.4	1.2	0.9	-0.5	1.0	-0.2	1.2	0.8	0.6
Hypothyroidism (self reported)	0.2	0.5	2.2	-0.6	1.0	1.5	-0.4	-0.1	-0.5	-0.3	-0.1
Respiratory disease	1.5	3.4	6.5	-2.0	-2.5	-1.0	-1.9	-1.5	-1.9	-1.6	-1.8
Type 2 Diabetes (T2D) (2018)	0.2	0.5	0.9	-0.2	-0.4	0.8	-0.6	-0.9	-0.5	-0.9	-0.6
Lung FEV1/FVC ratio	0.1	0.5	1.1	-0.6	-1.0	1.1	-0.5	-0.8	-0.5	-0.6	-0.3
Lung FVC	1.8	9.0	13.3	2.9	-0.4	2.4	3.4	3.6	3.3	3.0	3.6
Neuroticism	1.0	2.4	4.4	-1.4	-0.4	-1.1	-1.6	-2.1	-1.5	-1.7	-1.9
Chronotype (morning person)	0.1	0.3	0.5	0.6	-0.4	0.0	0.7	0.6	0.6	0.6	0.7
Hair Pigment	0.1	3.1	5.7	-1.4	-0.8	1.3	-1.8	-2.4	-1.7	-2.2	-2.0
Tanning	0.1	0.6	1.3	0.8	0.5	1.1	0.9	0.5	0.7	0.9	0.7
Hand grip strength (left)	0.2	0.5	1.3	0.2	-0.7	0.6	0.7	1.1	0.5	0.7	0.6
Number of treatments/medications taken	0.3	0.6	4.8	-0.0	0.0	-2.2	-0.1	-0.3	-0.2	-0.0	-0.0
Average weekly spirits intake	0.7	0.9	1.7	-0.5	-1.1	-0.1	-1.0	-1.3	-0.8	-1.2	-1.0
Sensitivity / hurt feelings	0.3	0.5	2.6	-0.4	-0.3	-1.6	-0.4	-0.8	-0.5	-0.2	-0.7
Frequency of depressed mood in last 2 weeks	1.9	2.7	3.7	-1.6	-0.7	-1.8	-1.7	-1.6	-1.7	-1.8	-1.9
Hearing difficulty/problems: Yes	0.9	1.4	2.5	-0.9	-0.7	-0.4	-1.5	-1.4	-1.1	-1.2	-1.6
Relative age of first facial hair	0.3	0.7	3.9	-0.4	-0.9	2.0	-0.4	0.3	-0.5	-0.0	-0.3
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	2.6	-0.1	0.6	1.6	-0.3	-0.5	-0.2	-0.2	-0.1
Ever used hormone-replacement therapy (HRT)	0.5	0.6	0.9	-0.6	-0.1	0.5	-0.9	-0.9	-0.9	-0.9	-0.9
Ever had hysterectomy (womb removed)	0.3	0.4	2.4	-0.5	-0.0	-1.6	-0.2	-0.2	-0.4	-0.4	-0.0
Systolic blood pressure, automated reading	0.0	0.1	0.3	0.6	0.1	-0.4	0.2	0.2	0.2	0.1	0.1
Eye problems/disorders: Diabetes related eye disease	0.3	0.4	2.4	-0.1	-0.3	1.6	-0.2	-0.4	-0.1	-0.2	-0.2
Angina	1.5	2.0	3.0	-1.7	-0.8	-0.9	-1.5	-1.5	-1.7	-1.5	-1.3
Medication for hormone replacement therapy	1.1	1.2	1.6	-1.2	-0.8	0.9	-1.2	-0.6	-1.2	-1.3	-1.3
Vitamin and mineral supplements	1.0	1.4	2.6	1.6	-0.4	1.5	1.2	0.9	1.4	1.1	1.0
Supplements: Zinc	4.0	4.3	6.3	2.1	0.8	-0.5	2.4	2.3	2.3	2.5	2.5
Medication: Co-codamol	0.4	0.5	1.6	-0.4	1.3	0.2	-0.4	-0.8	-0.5	-0.7	-0.6
Medication: Metformin	1.7	2.4	3.7	-1.4	-1.6	-0.7	-1.7	-1.6	-1.6	-1.9	-1.5
Diabetes (father)	0.6	0.7	3.5	-0.0	-1.4	-1.9	-0.2	-0.3	-0.1	-0.2	-0.3
Diabetes (mother)	0.4	0.6	2.5	-0.2	-0.1	-1.6	-0.4	-1.0	-0.3	-0.6	-0.5
Severe depression (siblings)	0.2	0.2	0.4	-0.3	0.5	-0.2	-0.7	-0.3	-0.4	-0.4	-0.6
Pack years adult smoking proportion	1.4	2.1	3.1	-1.2	-1.4	-1.3	-1.4	-1.8	-1.4	-1.5	-1.5
Impedance of leg (right)	0.2	1.1	4.2	0.7	-0.1	-2.1	0.5	1.3	0.8	1.2	0.5
Leg fat-free mass (left)	0.7	3.7	7.0	-2.0	-0.6	2.0	-1.7	-2.6	-2.0	-2.1	-1.8
Trunk fat percentage	3.3	13.1	28.4	-3.4	-0.4	-1.1	-3.9	-5.3	-4.0	-3.9	-4.1
Hand grip strength (right)	0.6	1.6	3.2	0.8	-0.3	1.6	1.3	1.8	1.1	1.2	1.3
Townsend deprivation index at recruitment	0.2	0.2	0.6	0.3	0.4	0.3	-0.6	-0.6	-0.3	-0.5	-0.8
Current tobacco smoking	0.6	0.9	2.2	-0.5	-0.5	0.9	-1.1	-1.5	-0.8	-0.9	-0.9
Average weekly fortified wine intake	0.8	1.0	2.9	0.4	1.7	0.4	1.0	1.1	0.8	0.9	1.0
Maternal smoking around birth	0.4	0.6	2.3	-0.4	0.3	-1.4	-0.2	-1.5	-0.4	-0.0	-0.7
Fed-up feelings	5.8	10.5	16.3	-3.3	-3.2	-1.2	-3.5	-4.0	-3.5	-3.1	-3.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	1.5	-0.3	0.7	-0.5	-0.8	-1.2	-0.6	-0.8	-1.2
Relative age voice broke	0.4	0.6	1.9	0.1	-1.4	1.4	0.0	0.7	0.1	0.4	0.4
Taking other prescription medications	0.1	0.2	0.4	-0.2	-0.1	-0.6	-0.5	-0.5	-0.4	-0.2	-0.2
Age when periods started (menarche)	1.1	2.7	3.8	1.9	-0.5	0.9	1.7	1.9	1.8	1.9	1.8
Bilateral oophorectomy (both ovaries removed)	3.2	3.7	5.0	2.0	1.9	1.4	2.1	1.9	1.9	2.0	2.2
Heel bone mineral density (BMD) T-score, automated (left)	2.1	4.9	7.6	-2.8	-1.8	-0.6	-2.5	-2.0	-2.6	-2.5	-2.2
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	3.0	0.7	-0.9	-1.7	0.6	0.9	0.8	0.7	0.3
Qualifications: CSEs or equivalent	1.6	2.1	2.7	-1.3	-1.0	-1.6	-1.5	-1.6	-1.4	-1.6	-1.5
Serious illness, injury or assault to yourself	0.1	0.2	0.7	0.4	-0.4	0.8	0.2	-0.0	0.3	0.3	0.4
High blood pressure	1.0	2.8	6.3	2.5	1.4	-0.6	1.8	1.1	2.2	1.8	1.2
Hayfever, allergic rhinitis or eczema	0.3	0.6	4.5	0.1	-0.3	-2.1	-0.3	-0.3	-0.0	-0.3	-0.3
Multivitamins +/- minerals	1.1	1.4	5.6	-1.3	0.4	-2.4	-0.9	-0.6	-1.0	-1.0	-0.8
Stomach or abdominal pain in last month	0.4	0.5	3.5	0.2	1.9	0.1	-0.2	-0.6	0.0	-0.2	-0.3
Supplements: Glucosamine	0.1	0.1	0.3	0.2	-0.4	-0.5	0.3	0.6	0.3	0.2	0.2
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	2.9	-1.0	-0.5	0.7	-1.1	-1.7	-1.0	-1.1	-1.3
Medication: Atenolol	1.2	1.5	3.1	1.8	0.7	-1.6	1.1	0.6	1.4	1.2	0.9
Medication: Levothyroxine sodium	0.2	0.4	1.1	0.4	1.0	1.0	0.3	0.5	0.3	0.4	0.6
Sitting height	0.0	0.3	1.0	-1.0	-0.8	0.2	-0.4	0.1	-0.6	-0.4	-0.3
Chronic bronchitis/emphysema (father)	0.9	1.0	1.8	0.9	-0.1	-1.3	1.0	1.2	1.2	1.1	0.8
High blood pressure (mother)	0.8	1.1	1.8	1.1	-0.1	-0.1	1.4	1.2	1.3	1.3	1.0
Body mass index (BMI)	2.4	10.2	21.9	-3.1	-0.8	-0.2	-3.3	-4.7	-3.5	-3.8	-3.4
Impedance of leg (left)	0.3	1.2	6.1	0.5	-0.8	-2.5	0.4	1.1	0.6	1.0	0.3
Leg predicted mass (left)	0.7	3.7	7.0	-2.0	-0.6	2.0	-1.7	-2.6	-2.0	-2.1	-1.7
Trunk fat mass	3.2	13.8	29.1	-3.7	-0.9	-0.6	-4.0	-5.4	-4.2	-4.1	-4.1
Waist circumference	2.2	8.2	18.5	-2.6	-0.6	0.2	-3.1	-4.3	-3.1	-3.3	-3.1
Number of incorrect matches in round	0.7	1.2	1.8	1.2	1.3	0.2	1.1	1.2	1.1	0.9	1.3
Past tobacco smoking	0.9	1.6	5.4	-1.3	-2.3	-1.3	-0.8	-0.9	-1.0	-0.9	-0.8
Alcohol usually taken with meals	0.4	0.6	1.0	0.5	-0.5	0.5	0.8	1.0	0.8	1.0	0.9
Nervous feelings	0.5	0.9	1.6	-0.4	1.0	-0.3	-1.0	-1.3	-0.8	-1.0	-1.2
Frequency of tenseness / restlessness in last 2 weeks	3.9	6.1	9.1	-2.5	-2.1	-1.8	-2.7	-2.6	-2.4	-2.5	-3.0
Hearing difficulty/problems with background noise	0.2	0.2	0.9	0.1	1.0	0.3	0.3	0.5	0.3	0.6	0.4
Hair/balding pattern: Pattern 2	1.0	1.2	1.9	1.4	-0.3	-0.7	1.3	1.1	1.3	1.3	1.0
Had menopause	1.4	1.7	2.2	1.4	0.8	0.6	1.5	1.5	1.5	1.4	1.5
Had other major operations	0.8	1.0	2.0	-0.8	-0.8	-1.4	-0.9	-0.9	-0.9	-1.2	-1.0
Forced vital capacity (FVC)	0.2	0.7	2.1	0.1	-0.6	1.4	0.6	1.3	0.5	0.4	0.8
Heel bone mineral density (BMD) T-score, automated (right)	1.7	3.9	5.5	-2.4	-1.7	-0.9	-2.4	-1.7	-2.2	-2.2	-2.0
Ever unenthusiastic/disinterested for a whole week	2.2	2.7	4.2	-1.4	-0.8	-1.5	-1.7	-2.0	-1.6	-1.8	-2.1
Qualifications: None of the above	0.1	0.3	0.6	0.8	0.6	-0.4	0.4	-0.4	0.6	0.3	0.4
Financial difficulties in last 2 years	0.1	0.1	0.5	0.0	0.7	-0.2	-0.1	-0.3	-0.1	0.0	-0.2
Mouth/teeth dental problems	0.8	1.2	1.8	-1.3	-1.3	0.8	-1.2	-0.6	-1.3	-1.0	-0.8
Heart attack	0.9	1.2	3.2	-0.7	0.5	-1.8	-1.0	-1.2	-0.9	-1.1	-1.0
Allergy	0.4	1.0	3.6	0.5	1.4	1.9	0.7	0.6	0.5	0.6	0.7
Pain all over the body in last month	2.5	2.6	4.0	-1.8	-0.5	0.2	-1.9	-2.0	-1.7	-1.9	-1.9
Diabetes (self-reported)	0.1	0.2	0.5	0.5	-0.5	0.7	0.3	0.0	0.4	0.1	0.3
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	1.4	0.4	0.4	-1.2	-0.1	0.3	0.1	-0.1	0.0
Medication: Ramipril	0.2	0.2	0.5	0.0	0.7	-0.1	-0.5	-0.6	-0.3	-0.6	-0.4
Medication: Simvastatin	2.7	3.9	5.9	2.0	1.6	-1.3	2.4	1.8	2.1	2.2	2.0
Fluid intelligence score	0.6	1.2	2.3	0.5	-1.5	1.0	1.0	1.4	0.8	1.1	1.1
Illnesses of siblings	0.3	0.4	0.9	-0.8	-0.9	0.5	-0.7	-0.5	-0.7	-0.5	-0.5
Neuroticism score	1.8	3.7	6.6	-1.8	-0.9	-1.3	-2.0	-2.6	-2.1	-1.9	-2.3
Weight	1.8	8.9	17.4	-3.1	-1.1	0.9	-3.2	-4.2	-3.3	-3.4	-3.1
Impedance of arm (right)	0.1	0.5	2.0	0.5	1.4	-0.1	0.2	0.4	0.3	1.1	0.1
Arm fat percentage (right)	2.5	10.0	23.3	-2.8	0.2	-0.1	-3.4	-4.8	-3.4	-3.5	-3.5
Trunk fat-free mass	0.3	2.0	5.5	-1.5	-1.1	2.4	-1.0	-1.2	-1.2	-1.4	-0.8
Hip circumference	1.9	8.1	16.4	-3.0	-0.3	0.9	-3.0	-4.1	-3.2	-3.3	-2.9
Time employed in main current job	2.0	2.4	3.9	1.3	1.2	0.9	2.0	1.2	1.6	1.9	1.9
Alcohol intake versus 10 years previously	0.2	0.3	1.0	0.2	1.0	0.1	-0.4	-0.8	-0.1	-0.5	-0.5
Father’s age at death	1.5	2.0	2.8	1.3	1.4	-0.4	1.6	1.7	1.6	1.5	1.4
Worrier / anxious feelings	0.1	0.2	1.1	0.0	0.8	-1.0	-0.1	0.1	0.1	-0.1	-0.2
Frequency of tiredness / lethargy in last 2 weeks	2.7	4.3	8.1	-1.6	-0.6	-1.9	-2.3	-2.6	-2.0	-2.0	-2.8
Falls in the last year	3.1	4.1	5.7	-2.3	-1.0	-0.1	-2.3	-2.4	-2.3	-2.2	-2.4
Hair/balding pattern: Pattern 3	1.0	1.5	2.4	-1.1	-1.5	0.6	-1.2	-1.5	-1.1	-1.4	-1.1
Number of live births	0.2	0.3	2.1	-0.2	-0.1	-1.4	-0.2	-0.2	-0.0	-0.1	-0.3
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	2.2	-0.3	-1.4	1.5	0.3	1.1	0.2	0.0	0.6
Pulse rate	0.4	0.6	2.1	-1.1	-1.4	-0.1	-0.6	0.0	-0.9	-0.6	-0.4
Happiness	1.4	1.7	2.5	-1.6	-1.4	0.5	-1.3	-1.0	-1.5	-1.4	-1.4
Noisy workplace	0.7	0.9	1.2	-0.8	0.8	-0.7	-1.1	-1.0	-1.0	-1.0	-1.1
Qualifications: A levels/AS levels or equivalent	0.3	0.7	2.4	0.5	0.2	-0.6	0.8	1.5	0.7	1.0	0.7
Serious illness, injury or assault of a close relative in last 2 years	2.7	3.1	6.0	-1.7	-0.6	-1.1	-1.9	-2.5	-1.8	-1.9	-2.0
Mouth/teeth dental problems: Dentures	0.8	1.3	4.1	1.2	2.0	-1.1	1.1	0.5	1.0	0.7	0.8
Asthma	3.2	6.3	13.6	-2.8	-3.7	-2.4	-2.3	-1.8	-2.5	-2.0	-2.0
Medication: Ibuprofen (e.g. Nurofen)	1.5	1.9	3.0	-1.2	-0.7	1.1	-1.4	-1.7	-1.3	-1.5	-1.7
Medication: Cholesterol lowering	0.6	1.0	4.8	0.6	0.2	-2.2	1.0	0.5	0.7	0.7	0.8
Depression (self-reported)	1.0	1.2	1.6	-1.2	-0.5	-1.1	-1.2	-0.9	-1.3	-1.2	-1.3
Medication: Lansoprazole	2.4	2.7	4.9	-1.3	-0.5	0.4	-1.9	-2.2	-1.7	-2.2	-1.7
Prospective memory result	1.0	1.3	4.8	0.8	2.2	-1.2	0.7	0.9	0.9	0.6	0.8
Lung cancer (father)	0.2	0.3	1.3	0.3	-0.1	1.1	0.3	0.4	0.3	0.5	0.3
Illnesses of mother	0.9	1.2	1.7	-1.1	-1.3	0.6	-1.2	-1.1	-1.1	-1.2	-0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.5	3.0	-0.3	-0.6	1.7	0.2	0.6	0.1	-0.1	0.3
Pulse wave Arterial Stiffness index	0.1	0.1	0.5	-0.2	0.0	-0.1	-0.0	-0.7	-0.1	-0.3	-0.3
Impedance of arm (left)	0.1	0.3	1.6	0.2	1.3	-0.1	-0.1	0.2	-0.0	0.8	-0.1
Arm fat mass (right)	2.3	9.5	20.9	-2.9	-0.3	0.5	-3.3	-4.6	-3.4	-3.6	-3.4
Trunk predicted mass	0.4	2.0	5.7	-1.6	-1.1	2.4	-1.1	-1.2	-1.2	-1.4	-0.8
Standing height	0.1	1.0	6.3	-0.6	-1.1	2.5	-0.1	0.5	-0.2	0.3	0.1
Length of working week for main job	0.3	0.3	1.3	0.1	0.1	1.1	-0.4	-0.6	-0.3	-0.7	-0.5
Exposure to tobacco smoke at home	2.1	2.3	5.3	1.4	2.3	1.9	1.4	0.6	1.2	1.3	1.4
Breastfed as a baby	1.0	1.2	6.8	-0.3	-1.6	-2.6	-0.1	0.1	-0.0	-0.5	-0.2
Tense / ‘highly strung’	0.6	0.9	4.7	1.0	2.2	0.5	0.7	0.3	0.8	0.7	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	2.4	3.7	4.7	-1.8	-1.9	-1.5	-2.0	-2.1	-1.9	-1.9	-2.2
Hair/balding pattern: Pattern 4	0.3	0.6	2.4	0.0	1.6	1.3	0.4	0.4	0.2	0.4	0.5
Birth weight of first child	0.3	0.6	2.7	-0.2	-0.4	1.6	-0.6	-0.8	-0.5	-0.6	-0.5
Peak expiratory flow (PEF)	0.4	1.0	3.2	-1.3	-1.8	0.5	-0.7	-0.4	-1.0	-0.9	-0.3
Pulse wave reflection index	0.2	0.2	1.1	0.5	1.1	-0.2	0.2	-0.4	0.5	0.1	-0.3
Ever highly irritable/argumentative for 2 days	1.0	1.2	2.3	-1.0	-0.4	-0.1	-0.9	-1.5	-1.2	-1.2	-1.5
Loud music exposure frequency	0.6	0.6	1.6	-0.7	-0.5	1.3	-1.0	-0.4	-0.6	-0.6	-1.0
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	2.2	-1.0	-1.5	-0.4	-0.5	0.2	-0.7	-0.3	-0.5
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.2	-0.6	0.1	0.4	-0.6	-1.1	-0.6	-0.6	-0.8
Blood clot in the leg (DVT)	0.1	0.2	0.5	0.5	0.7	-0.3	0.3	0.4	0.3	0.3	0.3
Medication: Paracetamol	0.1	0.1	0.3	0.0	0.5	-0.5	-0.2	-0.6	-0.1	-0.2	-0.2
Headache pain in last month	0.4	0.6	3.4	0.2	1.8	-0.2	-0.3	-1.0	-0.2	-0.2	-0.6
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	0.7	-0.6	-0.5	0.9	-0.8	-0.2	-0.6	-0.6	-0.5
Glaucoma (self-reported)	0.8	1.0	1.8	1.1	0.7	0.3	1.2	0.8	1.3	1.3	0.6
Gout (self-reported)	1.2	1.6	2.2	1.5	-1.1	0.5	1.4	1.5	1.4	1.2	1.4
Hypothyroidism/myxoedema (self-reported)	0.7	1.4	4.2	0.6	1.6	2.0	0.7	1.3	0.6	0.9	1.1
Medication: Amlodipine	3.9	5.5	7.8	2.7	1.7	-0.9	2.7	2.5	2.8	2.6	2.1
Medication: Ventolin 100micrograms inhaler	2.1	2.6	9.9	-1.9	-3.2	-1.1	-1.2	-1.0	-1.4	-1.0	-1.0
Birth weight	0.2	0.4	2.8	-0.3	-0.2	1.7	-0.2	-0.0	-0.3	-0.2	0.0
Chronic bronchitis/emphysema (mother)	0.4	0.5	0.9	0.7	0.6	-0.5	0.6	0.9	0.7	0.9	0.4
High blood pressure (siblings)	0.9	1.2	2.3	1.3	1.5	0.2	1.2	1.0	1.2	1.0	1.0
Forced vital capacity (FVC), Best measure	0.2	0.6	3.4	-0.3	-0.8	1.8	0.1	0.6	0.0	-0.2	0.3
Body fat percentage	3.3	13.2	28.1	-3.4	-0.7	-1.3	-3.9	-5.3	-4.0	-4.0	-4.1
Leg fat percentage (right)	3.0	10.9	22.2	-3.1	-1.2	-1.6	-3.5	-4.7	-3.6	-3.7	-3.6
Arm fat-free mass (right)	0.5	2.8	4.0	-2.0	-1.4	1.1	-1.5	-1.9	-1.8	-2.0	-1.5
Exposure to tobacco smoke outside home	0.3	0.3	1.3	-0.3	0.4	1.1	-0.3	-0.8	-0.4	-0.2	-0.5
Comparative body size at age 10	1.3	3.6	7.3	-1.7	-0.6	-1.9	-1.8	-2.7	-1.9	-2.2	-1.9
Number of full brothers	0.2	0.2	0.6	0.1	-0.4	-0.7	-0.3	-0.4	-0.1	-0.5	-0.8
Worry too long after embarrassment	1.2	2.1	3.4	-1.4	-0.5	-1.2	-1.5	-1.8	-1.5	-1.4	-1.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.8	1.4	-0.8	-0.8	-0.3	-1.1	-1.1	-0.9	-1.0	-1.2
Wheeze or whistling in the chest in last year	1.5	2.8	4.8	-1.8	-2.2	-0.7	-1.5	-2.1	-1.7	-1.3	-1.5
Number of children fathered	0.7	0.8	3.7	0.1	-1.9	-0.3	0.5	1.1	0.3	0.6	0.9
Reason for reducing amount of alcohol drunk: Health precaution	2.5	2.9	4.1	2.0	2.0	0.2	1.6	1.8	1.9	1.6	1.7
Age at first live birth	0.3	0.6	2.2	-1.5	-0.6	1.1	-0.4	0.2	-1.0	-0.3	-0.1
Pulse wave peak to peak time	0.1	0.1	0.2	-0.2	-0.4	0.4	-0.3	0.5	-0.3	0.0	0.0
Health satisfaction	0.7	0.9	1.5	-1.0	-1.1	0.1	-1.0	-1.2	-1.1	-0.7	-1.0
Shortness of breath walking on level ground	0.4	0.5	1.5	-0.6	-0.3	1.0	-0.3	-1.2	-0.7	-0.4	-0.4
Qualifications: College or University degree	0.6	2.0	6.3	1.0	0.7	-0.4	1.4	2.5	1.4	1.7	1.1
Eye problems/disorders: None of the above	0.2	0.2	0.9	0.2	0.4	-0.4	0.2	1.0	0.2	0.2	0.5
Mouth/teeth dental problems: Loose teeth	0.8	1.0	3.5	-0.4	-0.4	-1.9	-0.7	-1.2	-0.6	-0.7	-1.1
Emphysema/chronic bronchitis	0.2	0.2	0.6	0.6	0.7	0.1	0.0	-0.5	0.3	-0.1	-0.3
Medication for pain relief, constipation, heartburn	0.6	1.0	2.7	0.6	-0.6	1.6	0.9	1.4	0.8	0.8	1.0
Neck or shoulder pain in last month	3.1	4.4	6.0	-1.9	-1.5	-1.9	-2.2	-2.4	-1.9	-2.3	-2.4
Medication: Blood pressure	0.1	0.1	0.4	0.6	-0.1	-0.3	0.4	-0.1	0.5	0.4	0.3
Angina (self-reported)	1.7	2.2	3.3	-1.8	-0.8	-0.9	-1.6	-1.7	-1.8	-1.6	-1.4
Migraine (self-reported)	0.8	1.0	2.0	-0.7	-1.4	-1.2	-1.2	-0.4	-0.8	-0.9	-0.9
Medication: Ibuprofen	0.3	0.3	0.8	-0.1	-0.4	0.9	-0.3	-0.9	-0.2	-0.5	-0.7
Medication: Allopurinol	0.8	1.0	6.1	0.6	-2.5	0.3	0.6	0.7	0.5	0.4	0.7
Medication: Omeprazole	0.4	0.5	0.8	-0.7	-0.5	0.9	-0.9	-0.7	-0.9	-0.5	-0.6
Medication: Seretide 50 evohaler	3.0	3.5	9.6	-1.4	-3.1	-3.1	-1.2	-0.9	-1.2	-1.4	-1.1
Mean time to correctly identify matches	0.4	0.7	3.5	-0.4	1.9	0.9	-0.5	0.0	-0.6	-0.4	-0.6
Heart disease (mother)	0.4	0.5	1.8	0.7	1.4	-0.0	0.4	0.5	0.6	0.6	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	5.0	-0.8	-2.1	-2.2	-0.3	0.6	-0.5	-0.2	0.1
Whole body fat mass	3.5	14.4	29.0	-3.8	-1.2	-0.6	-4.1	-5.4	-4.2	-4.3	-4.2
Leg fat mass (right)	2.6	10.1	21.2	-3.1	-1.0	-0.6	-3.3	-4.6	-3.5	-3.7	-3.4
Arm predicted mass (right)	0.6	3.0	4.2	-1.9	-1.3	1.5	-1.6	-2.0	-1.8	-2.0	-1.5
Pulse rate, automated reading	0.5	1.6	3.6	-0.6	-1.9	-0.3	-1.3	-1.1	-0.9	-1.7	-1.4
Alcohol intake frequency.	2.1	4.9	6.2	-2.5	-1.7	-1.4	-2.4	-2.3	-2.4	-2.3	-2.5
Comparative height size at age 10	0.5	2.7	4.3	-2.1	-0.6	0.3	-1.9	-1.7	-1.8	-1.8	-2.0
Number of full sisters	0.2	0.2	1.4	0.4	1.2	0.0	0.2	0.4	0.3	0.2	-0.1
Suffer from ‘nerves’	0.8	1.3	2.3	-0.5	1.5	-0.6	-1.2	-1.4	-1.0	-1.2	-1.4
Overall health rating	0.9	2.0	5.8	-0.9	0.3	0.4	-1.5	-2.4	-1.2	-1.5	-1.7
Chest pain or discomfort	3.2	4.7	5.6	-2.3	-1.7	-1.9	-2.1	-2.4	-2.3	-2.1	-2.3
Had major operations	2.7	3.2	6.5	1.6	-0.6	0.1	2.0	2.6	1.9	2.1	2.0
Age at last live birth	0.3	0.4	1.0	-0.9	-0.9	1.0	-0.3	0.3	-0.5	-0.1	-0.2
Family relationship satisfaction	1.2	1.5	2.0	1.1	0.4	1.3	1.4	1.4	1.1	1.3	1.3
Leg pain on walking	0.1	0.2	0.6	-0.2	-0.8	-0.2	-0.4	0.1	-0.3	-0.5	-0.3
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.7	3.2	0.1	1.8	-0.4	-0.4	-0.8	-0.3	-0.7	-0.7
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.4	0.2	-0.2	-0.4	-0.1	-0.6	0.1	-0.1	-0.5
Illness, injury, bereavement, stress in last 2 years	2.9	3.6	7.7	1.4	0.3	1.5	2.0	2.8	1.8	2.2	2.2
Medication: Aspirin	0.6	0.7	1.8	0.6	1.3	-1.4	0.7	0.3	0.5	0.7	0.8
Supplements: Vitamin C	1.1	1.3	2.0	-1.2	-0.4	-1.4	-1.2	-1.0	-1.1	-1.0	-1.4
Knee pain experienced in last month	0.1	0.1	0.4	0.3	0.6	0.5	-0.1	-0.5	0.0	-0.1	-0.1
Hypertension (Self-reported)	1.1	2.9	6.5	2.6	1.3	-0.7	1.9	1.0	2.2	1.9	1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	4.7	5.5	7.6	-2.4	-1.2	0.7	-2.8	-2.7	-2.6	-2.6	-2.7
Illnesses of father: Heart disease	0.5	0.7	4.5	-0.0	-0.8	-2.1	0.1	0.0	0.1	-0.2	0.2
Illnesses of siblings: Diabetes	1.7	2.1	3.3	-1.4	-1.6	-1.8	-1.4	-1.1	-1.4	-1.1	-1.6
Smoking status: Previous	2.0	3.0	6.0	1.8	2.5	1.1	1.7	1.6	1.7	1.7	1.6
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.8	2.9	-1.7	-0.7	1.2	-1.3	-1.5	-1.5	-1.2	-1.5
Whole body fat-free mass	0.5	2.9	4.8	-1.9	-1.1	2.2	-1.4	-1.9	-1.7	-1.9	-1.3
Leg fat-free mass (right)	0.6	3.3	6.0	-1.9	-0.7	1.9	-1.6	-2.5	-1.9	-2.0	-1.6
Arm fat percentage (left)	2.6	10.6	24.6	-3.0	0.1	-0.2	-3.5	-5.0	-3.6	-3.6	-3.6
Average weekly red wine intake	0.3	0.5	1.3	-1.1	-1.0	-0.5	-0.4	0.1	-0.6	-0.7	-0.5
Handedness (chirality/laterality): Left-handed	2.5	3.0	4.9	-1.8	-1.1	-1.4	-1.8	-2.0	-1.7	-2.2	-1.6
Mood swings	3.2	5.9	9.0	-2.3	-2.6	-1.5	-2.5	-3.0	-2.5	-2.2	-2.4
Loneliness, isolation	0.2	0.3	1.2	-0.4	-0.3	-0.2	-0.7	-1.1	-0.5	-0.5	-0.5
Long-standing illness, disability or infirmity	0.0	0.1	0.1	0.2	0.4	-0.4	-0.2	-0.2	-0.0	-0.2	-0.3
Ever had bowel cancer screening	0.4	0.5	1.0	-0.4	-0.8	-0.5	-0.8	-0.5	-0.5	-1.0	-0.8
Diabetes diagnosed by doctor	0.0	0.0	0.1	0.0	-0.2	0.2	-0.1	-0.3	-0.1	-0.2	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.4	0.3	-0.6	0.1	0.3	0.4	0.3	0.2	0.3
Friendships satisfaction	0.4	0.5	3.9	-0.1	-2.0	-0.3	0.1	0.5	0.1	0.2	0.2
Qualifications: nursing, teaching	0.8	1.2	4.2	-1.2	-2.0	-1.7	-0.5	-0.0	-0.7	-0.1	-0.6
Commuting to job workplace: Walk	2.0	2.2	3.7	1.1	1.1	-0.4	1.8	1.9	1.3	1.9	1.6
Eye problems/disorders: Cataract	0.4	0.5	1.2	-0.5	-1.0	0.4	-0.6	-1.1	-0.6	-0.6	-0.6
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	1.8	0.2	-1.3	-0.6	0.5	0.7	0.4	0.6	0.4
Medication for cholesterol	0.2	0.4	0.7	-0.8	-0.7	0.8	-0.5	-0.3	-0.6	-0.5	-0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.7	3.0	-1.7	0.1	-0.6	-1.5	-1.2	-1.6	-1.4	-1.6
Back pain experienced in last month	0.9	1.4	3.3	0.9	1.6	1.8	1.1	0.5	1.1	0.9	0.9
Mineral and other dietary supplements	0.4	0.6	1.9	-0.2	-0.3	1.4	-0.6	-1.2	-0.4	-0.6	-0.6
Breast cancer (self-reported)	0.7	0.8	1.2	-0.9	-0.7	-0.4	-1.1	-0.9	-1.0	-1.0	-1.0
Asthma (self-reported)	3.5	7.1	15.2	-3.0	-3.9	-2.2	-2.5	-2.1	-2.7	-2.2	-2.2
Osteoporosis (self-reported)	0.7	0.9	3.8	0.9	1.9	1.3	0.5	-0.0	0.7	0.4	0.4
Osteoarthritis (self-reported)	0.0	0.1	0.2	0.1	-0.0	0.5	-0.0	-0.3	0.1	-0.3	-0.0
Medication: Aspirin	0.9	1.2	2.8	0.8	1.4	-1.7	1.0	0.6	0.7	1.0	1.1
Medication: Gliclazide	0.1	0.2	0.4	-0.2	0.4	-0.3	-0.5	-0.3	-0.3	-0.6	-0.5
Illnesses of father: None of the above (group 1)	1.0	1.2	4.5	-0.9	-0.3	2.1	-0.8	-1.1	-1.1	-0.8	-0.8
Smoking status: Current	0.8	1.3	3.1	-0.6	-0.6	0.9	-1.4	-1.8	-1.0	-1.2	-1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	5.1	-0.2	-1.3	2.3	-0.0	0.4	-0.1	-0.2	0.5
Whole body water mass	0.5	2.7	4.9	-1.8	-1.0	2.2	-1.4	-1.9	-1.6	-1.8	-1.3
Leg predicted mass (right)	0.7	3.7	6.7	-2.0	-0.8	2.0	-1.7	-2.6	-2.0	-2.1	-1.8
Arm fat mass (left)	2.5	10.1	22.4	-3.0	-0.3	0.4	-3.4	-4.7	-3.5	-3.7	-3.5
Number of self-reported non-cancer illnesses	0.7	1.2	2.8	-0.7	-1.1	-1.7	-1.1	-1.2	-0.8	-1.0	-1.1
Average weekly champagne plus white wine intake	2.5	3.4	6.7	1.8	0.1	0.6	1.9	2.6	2.1	2.2	2.0
Miserableness	2.5	4.4	5.4	-2.3	-2.1	-1.7	-2.0	-2.3	-2.2	-1.9	-2.2
Guilty feelings	0.2	0.4	2.1	-0.2	-0.7	-1.5	-0.1	-0.1	-0.1	0.1	-0.5
Wears glasses or contact lenses	0.1	0.1	0.4	0.1	0.4	0.6	0.5	0.1	0.3	0.4	0.2
Ever taken oral contraceptive pill	0.3	0.4	0.7	-0.5	-0.5	-0.7	-0.6	-0.6	-0.5	-0.6	-0.8
Hearing aid user	1.4	1.6	2.7	-1.1	-1.2	-0.1	-1.4	-1.5	-1.1	-1.4	-1.6
Mother’s age at death	0.2	0.2	1.0	-0.5	-1.0	-0.7	-0.2	0.3	-0.2	-0.0	-0.3
Financial situation satisfaction	3.3	4.0	5.7	-2.3	-1.8	0.5	-2.1	-2.2	-2.4	-1.9	-2.1
Tinnitus: Yes, now most or all of the time	3.6	4.2	6.4	-2.5	-1.2	-2.0	-2.1	-2.1	-2.4	-2.2	-1.7
Commuting to job workplace: Public transport	1.5	1.8	6.0	1.5	2.5	0.9	1.0	0.9	1.3	1.2	0.9
Eye problems/disorders: Glaucoma	0.2	0.2	0.4	0.6	0.2	-0.2	0.5	0.0	0.6	0.6	0.1
Medication: Blood pressure	1.8	3.3	5.8	2.4	2.1	-1.3	1.8	1.3	2.1	1.8	1.5
Pain type(s) experienced in last month: Hip pain	2.9	3.6	4.9	-2.1	-1.3	-1.0	-2.0	-2.2	-1.9	-2.2	-2.1
Supplements: Fish oil (including cod liver oil)	1.2	1.6	2.7	1.0	1.1	-0.7	1.4	1.6	1.3	1.4	1.4
High cholesterol (Self-reported)	3.3	5.8	8.9	2.6	0.9	-1.5	3.0	2.5	2.8	2.7	2.6
Medication: Bendroflumethiazide	2.1	3.3	5.1	2.3	1.0	-0.5	2.1	1.7	2.2	2.2	1.7
Medication: Paracetamol	0.1	0.1	0.4	0.3	0.6	-0.6	0.0	-0.4	0.1	-0.2	-0.1
Medication: Lisinopril	0.3	0.4	1.0	-1.0	-0.6	-0.2	-0.6	-0.4	-0.8	-0.6	-0.7
Medication: Atorvastatin	0.1	0.2	0.8	-0.2	-0.7	-0.9	-0.0	-0.3	-0.0	-0.1	0.1
Illnesses of father: High blood pressure	0.3	0.3	0.6	-0.5	-0.7	-0.8	-0.4	-0.5	-0.4	-0.5	-0.6
Alcohol drinker status: Never	0.7	0.8	1.4	-1.2	-0.6	-0.6	-0.8	-0.9	-1.1	-1.0	-1.0
Ever smoked	0.5	1.0	3.6	1.0	1.9	1.3	0.2	0.7	0.7	0.4	0.2
Basal metabolic rate	0.8	4.2	6.9	-2.2	-1.1	1.8	-1.9	-2.6	-2.2	-2.3	-1.9
Leg fat percentage (left)	3.4	12.4	24.5	-3.3	-1.7	-1.8	-3.7	-4.9	-3.8	-4.0	-3.7
Arm fat-free mass (left)	0.6	3.1	4.8	-2.0	-1.3	1.2	-1.7	-2.1	-1.9	-2.2	-1.6
Number of operations (self-reported)	0.6	0.9	5.7	-0.8	-2.4	-0.1	-0.5	-0.1	-0.6	-0.5	-0.1
Average weekly beer plus cider intake	0.2	0.4	1.1	0.5	1.0	-0.7	0.5	0.4	0.5	0.2	0.6
Irritability	1.0	1.7	2.6	-1.3	0.1	-0.1	-1.5	-1.5	-1.5	-1.4	-1.6
Risk taking	0.2	0.3	1.2	-0.4	-0.4	1.1	-0.4	-0.2	-0.3	-0.3	-0.4
Ever had prostate specific antigen (PSA) test	0.4	0.5	1.1	-0.8	0.4	0.2	-0.6	-1.0	-0.8	-0.6	-0.6
Fractured/broken bones in last 5 years	0.8	1.0	3.6	0.7	1.3	1.9	0.8	-0.1	0.7	0.9	0.7
Age started oral contraceptive pill	6.0	7.5	10.6	3.2	1.8	-1.0	3.0	3.3	3.2	2.8	2.8
Diastolic blood pressure, automated reading	0.8	2.4	5.6	-1.1	-1.6	-2.4	-1.4	-1.4	-1.3	-1.5	-1.5
Ever depressed for a whole week	0.7	0.8	4.3	0.2	-1.2	-2.1	0.3	0.5	0.3	0.4	-0.2
Unable to work because of sickness or disability	2.1	2.7	4.4	-1.3	-0.6	-1.0	-2.1	-1.7	-1.7	-2.0	-2.1
Commuting to job workplace: Cycle	0.5	0.6	2.9	-0.5	-0.6	1.7	0.2	0.7	-0.1	0.4	0.5
Myopia	0.9	1.3	2.4	1.4	0.3	0.4	1.3	1.0	1.3	1.5	1.1
Vascular/heart problems diagnosed by doctor	0.3	0.8	2.4	-1.5	-0.8	0.7	-0.8	-0.2	-1.2	-0.8	-0.3
Cholesterol lowering medication	3.2	4.7	7.4	2.5	1.1	-0.5	2.5	2.1	2.5	2.7	2.4
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	0.8	-0.8	-0.5	0.5	-0.8	-0.9	-0.8	-0.3	-0.6
Pain experienced in last month	0.3	0.5	1.6	0.4	-0.7	0.0	0.5	1.3	0.4	0.6	0.9
Supplements: Calcium	1.2	1.3	2.4	0.9	1.3	1.6	1.1	0.7	0.9	1.3	1.1
Basal cell carcinoma (self-reported)	1.3	1.5	2.2	1.1	0.3	1.5	1.2	1.3	1.2	1.3	1.5
Heart attack/myocardial infarction (self-reported)	0.8	1.1	3.0	-0.6	0.8	-1.7	-0.9	-1.1	-0.8	-1.0	-1.0
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.4	0.2	0.7	-0.4	-0.1	-0.0	-0.0	-0.0	0.0
Heart disease (siblings)	0.1	0.2	0.9	-0.3	-0.5	-0.9	0.1	-0.3	-0.1	0.1	0.3
Alcohol drinker status: Previous	2.3	2.6	4.9	-1.5	-2.2	-2.0	-1.4	-1.0	-1.5	-1.4	-1.5
Pack years of smoking	0.8	1.2	2.0	-0.8	-0.7	-1.3	-1.0	-1.4	-1.0	-1.2	-1.1
Impedance of whole body	0.1	0.4	1.8	0.1	0.4	-1.4	-0.1	0.4	0.0	0.7	-0.2
Leg fat mass (left)	2.8	10.8	22.3	-3.3	-1.4	-0.7	-3.4	-4.7	-3.6	-3.8	-3.5
Arm predicted mass (left)	0.9	4.4	6.6	-2.3	-1.6	1.2	-2.0	-2.6	-2.2	-2.6	-2.0