Hub : Genes

RP11-33B1.4

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adrenal Gland 0.1078 0.0436 2.4e-04 0.100 NA 0.155 NA 0.145 1.9e-04 NA 3.2e-06 NA 7.2e-06
2 GTEx Artery Aorta 0.1110 0.0480 1.6e-04 0.040 NA 0.045 NA 0.025 2.9e-03 NA 1.7e-03 NA 1.5e-02
3 GTEx Artery Coronary 0.1030 0.0540 5.4e-03 0.019 NA -0.003 NA 0.010 7.4e-02 NA 4.2e-01 NA 1.5e-01
4 GTEx Artery Tibial 0.1422 0.0500 2.0e-06 0.100 NA 0.062 NA 0.065 3.0e-08 NA 1.2e-05 NA 8.5e-06
5 GTEx Brain Caudate basal ganglia 0.1160 0.0500 1.1e-03 0.162 NA 0.117 NA 0.146 2.2e-05 NA 3.1e-04 NA 5.7e-05
6 GTEx Brain Cerebellar Hemisphere 0.1270 0.0630 2.9e-03 0.045 NA -0.008 NA 0.012 2.6e-02 NA 5.5e-01 NA 1.6e-01
7 GTEx Brain Cerebellum 0.1350 0.0740 6.9e-03 -0.009 NA -0.009 NA -0.010 7.7e-01 NA 7.4e-01 NA 8.4e-01
8 GTEx Colon Sigmoid 0.0970 0.0420 1.9e-03 0.032 NA 0.018 NA 0.045 2.6e-02 NA 7.2e-02 NA 1.1e-02
9 GTEx Esophagus Mucosa 0.2100 0.0690 4.2e-04 0.029 NA 0.023 NA 0.002 4.7e-03 NA 1.0e-02 NA 2.3e-01
10 GTEx Esophagus Muscularis 0.1630 0.0600 1.5e-03 0.000 NA 0.001 NA -0.003 3.1e-01 NA 2.8e-01 NA 5.5e-01
11 GTEx Heart Atrial Appendage 0.1190 0.0610 1.5e-03 0.105 NA 0.027 NA 0.053 2.0e-05 NA 2.1e-02 NA 2.0e-03
12 GTEx Liver 0.1800 0.0690 9.4e-05 0.143 NA 0.023 NA 0.120 8.8e-05 NA 7.5e-02 NA 3.2e-04
13 GTEx Lung 0.0975 0.0340 2.9e-07 0.100 NA 0.083 NA 0.086 4.2e-08 NA 6.3e-07 NA 4.2e-07
14 GTEx Muscle Skeletal 0.0428 0.0235 5.2e-03 0.019 NA 0.013 NA 0.020 5.6e-03 NA 1.6e-02 NA 4.2e-03
15 GTEx Nerve Tibial 0.2073 0.0644 2.2e-04 0.100 NA 0.094 NA 0.122 1.5e-07 NA 3.6e-07 NA 6.2e-09
16 GTEx Ovary 0.1320 0.0710 7.4e-03 0.067 NA 0.002 NA 0.018 1.0e-02 NA 2.9e-01 NA 1.2e-01
17 GTEx Pancreas 0.1980 0.0770 3.0e-05 0.051 NA 0.034 NA 0.050 3.3e-03 NA 1.4e-02 NA 3.8e-03
18 GTEx Skin Sun Exposed Lower leg 0.1170 0.0480 5.3e-03 0.010 NA 0.004 NA 0.010 4.5e-02 NA 1.5e-01 NA 4.7e-02
19 GTEx Testis 0.2280 0.0530 6.1e-16 0.314 NA 0.373 NA 0.369 1.6e-14 NA 1.5e-17 NA 2.5e-17
20 GTEx Thyroid 0.0660 0.0300 3.7e-04 0.066 NA 0.010 NA 0.046 8.7e-06 NA 5.7e-02 NA 1.8e-04
21 GTEx Uterus 0.2290 0.1200 2.9e-03 0.238 NA 0.087 NA 0.155 1.3e-05 NA 8.0e-03 NA 4.9e-04
22 GTEx Whole Blood 0.1310 0.0380 1.9e-12 0.155 NA 0.145 NA 0.148 3.5e-14 NA 2.9e-13 NA 1.4e-13

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bipolar Disorder (2018) 0.1 0.1 0.6 0.3 0.1 0.3 -0.2 0.2 0.1 -0.1 0.1 -0.3 -0.1 0.2 0.4 -0.0 -0.4 0.4 0.2 0.8 0.5 0.2 0.5 -0.2 0.1
Bipolar Disorder or Schizophrenia 0.2 0.4 1.1 1.1 0.4 -0.6 -0.5 0.4 -0.7 -0.4 -0.6 -0.9 -0.7 -0.0 0.8 -0.4 -0.3 -0.2 -0.7 0.8 -0.1 0.6 0.5 -1.0 -0.2
Depressed Affect (Nagel 2018) 0.3 0.7 3.3 -0.1 -0.1 0.5 -0.5 -0.3 -0.2 -0.4 -1.1 -1.4 -1.3 -0.3 -0.3 0.1 -0.9 -1.8 0.1 -0.8 -1.6 -0.4 -0.9 -0.6 0.0
Depression (Nagel 2018) 0.7 1.1 2.8 0.9 -1.1 -0.5 -1.0 1.2 -1.2 -0.9 -1.2 -0.4 -1.5 -0.9 1.5 -1.0 0.4 0.5 -1.0 1.2 0.2 1.1 1.1 -1.7 -1.3
Intelligence (Savage-Jansen 2018) 0.2 0.6 3.7 -0.5 -0.1 -0.3 -1.6 0.2 -0.1 -0.5 -0.5 -1.0 -0.8 -1.1 -0.1 -0.5 0.4 -1.7 -0.4 0.1 -1.9 0.1 -0.3 -0.7 -0.2
Neuroticism (Nagel 2018) 0.2 0.4 1.8 0.1 0.1 0.7 -0.7 -0.1 -0.2 -0.2 -0.6 -1.4 -0.9 -0.6 -0.1 -0.2 -0.2 -1.2 0.3 -0.6 -1.3 -0.3 -0.6 -0.6 0.0
Schizophrenia (2018) 0.2 0.5 1.1 1.1 0.5 -1.0 -0.5 0.4 -1.0 -0.5 -0.8 -0.9 -0.8 -0.2 0.7 -0.4 -0.1 -0.6 -1.1 0.4 -0.5 0.7 0.3 -1.1 -0.3
Schizophrenia vs Biploar Disorder 1.2 1.6 4.8 1.4 -0.5 -1.0 -1.4 1.4 -1.9 -1.2 -0.4 -0.2 -0.5 -1.5 1.3 -1.8 2.2 -0.1 -1.2 1.9 -0.3 1.4 1.2 -1.2 -1.2
Worry (Nagel 2018) 0.1 0.3 0.8 0.4 0.9 0.5 0.1 -0.6 0.4 0.6 0.9 -0.9 0.6 0.3 -0.5 0.2 0.2 -0.1 0.5 -0.5 0.0 -0.5 -0.7 0.1 0.5
Alzheimer’s Disease (in mother) 2.2 2.6 6.0 2.0 -2.4 -1.4 -1.5 2.1 -1.8 -1.2 -1.3 0.1 -0.9 -1.7 1.8 -1.8 1.7 -0.6 -1.6 1.9 -0.8 1.7 1.6 -1.9 -1.7
Alzheimer’s Disease (in father) 0.5 0.5 4.4 -0.8 2.1 0.2 1.0 -0.2 0.5 0.0 0.4 1.1 1.6 0.4 -0.3 0.4 0.4 0.4 0.3 -0.0 0.4 -0.4 -0.1 0.3 0.6
Alzheimer’s Disease (including proxy) 0.8 1.2 3.0 1.3 -0.8 -1.0 -0.5 1.5 -1.0 -0.9 -0.7 1.0 0.6 -1.0 1.2 -1.2 1.7 -0.3 -1.2 1.5 -0.6 1.1 1.1 -1.7 -1.0
Crohns Disease (2017) 1.7 3.7 11.6 0.5 -2.1 -1.7 -1.5 2.0 -2.2 -2.6 -2.0 0.6 -1.5 -2.2 2.7 -1.2 0.1 1.1 -2.2 1.7 0.7 2.3 2.3 -3.4 -1.9
Irritable Bowel Disease (IBD) 0.2 0.5 2.7 -0.3 -0.4 0.6 0.1 0.6 -0.5 -1.0 0.2 0.8 0.1 -0.3 1.1 0.2 -0.4 1.2 -0.0 0.4 0.8 0.4 0.9 -1.6 -0.2
Ulcerative Colitis (UC) 0.5 0.9 4.3 -0.3 0.7 2.1 0.8 -0.5 1.0 0.2 1.5 0.5 0.8 0.9 -0.6 1.1 -0.6 0.6 1.7 -0.5 0.4 -1.2 -0.5 0.3 1.0
Major Depression (MDD) 0.4 0.5 1.6 0.6 -1.3 -0.3 -1.2 0.6 -0.5 -0.1 -0.4 -0.7 -0.8 -0.9 0.3 -0.7 0.6 -1.0 -0.3 0.8 -0.6 0.6 0.3 -0.2 -0.4
Reaction Time 0.4 0.8 4.2 0.5 -0.1 0.2 1.3 -0.0 0.2 0.5 1.2 1.8 1.2 1.0 0.3 0.6 0.0 2.0 0.3 -0.0 1.8 0.1 0.6 0.1 0.5
Verbal and Numeric Reasoning (VNR) 0.5 1.2 4.6 0.8 -0.8 -1.0 -2.2 0.7 -0.5 -0.6 -0.7 -1.8 -1.9 -1.7 0.6 -1.1 0.8 -1.1 -1.1 1.0 -1.3 0.5 0.3 -1.0 -0.6
Breast Cancer 0.4 1.0 3.7 -0.8 1.2 0.3 1.2 -0.9 1.3 0.7 0.9 0.3 0.1 0.8 -0.8 1.2 -1.2 1.2 0.7 -0.8 1.9 -0.6 -0.6 1.3 1.2
Ovarian Cancer 1.7 2.3 9.9 -0.9 0.8 0.1 2.4 -0.9 0.0 1.6 1.1 2.6 2.1 2.3 0.0 0.9 -0.3 3.1 0.3 -0.5 3.1 -0.2 0.4 0.4 0.6
Prostate Cancer 0.5 0.7 3.3 -0.9 0.0 0.0 -0.2 -0.6 0.8 0.6 0.6 -1.8 -0.7 0.1 -0.7 0.6 -1.0 -1.7 0.1 -0.4 -1.1 -0.7 -1.1 0.4 0.6
Age at First Birth 3.2 4.6 8.8 0.9 -1.9 -1.8 -1.3 2.9 -3.0 -2.6 -2.6 1.5 -0.3 -2.1 2.6 -2.5 2.5 0.3 -2.2 2.1 -0.4 2.3 2.4 -2.9 -2.5
Bipolar Disorder (2011) 1.8 1.8 3.1 1.8 -0.9 -1.1 -1.3 1.6 -1.2 -1.8 -1.0 -0.0 -1.3 -1.2 1.7 -1.3 1.0 1.0 -1.4 1.5 0.7 1.6 1.6 -1.6 -1.3
Body Mass Index (BMI) (2010) 2.7 3.6 8.1 -2.1 1.8 1.2 1.1 -2.6 1.8 2.1 1.2 -1.6 -0.6 2.0 -2.1 2.3 -2.8 -0.6 1.4 -2.6 0.2 -2.3 -2.4 1.8 2.4
Coronary Artery Disease (CAD) 1.9 2.3 5.0 0.8 -0.5 -2.2 -2.1 1.7 -1.2 -1.7 -0.3 -0.1 -0.6 -2.1 1.6 -1.9 2.2 0.4 -2.1 2.2 0.8 1.8 1.4 -1.0 -1.2
Crohns Disease (2012) 1.9 3.1 8.7 1.0 -1.9 -1.2 -1.6 1.7 -2.4 -2.9 -1.8 0.4 -1.1 -2.3 2.1 -1.7 1.2 -0.2 -1.8 1.4 -0.5 1.9 1.6 -2.9 -2.1
Mean Putamen Volume 0.8 0.9 2.8 -0.3 0.5 0.3 1.7 -1.2 0.8 0.7 1.0 0.7 1.0 1.4 -1.2 1.3 -0.7 -0.4 0.6 -1.2 -0.5 -1.0 -1.1 1.1 1.0
Fasting Glucose 0.3 0.3 1.0 0.1 -0.2 0.7 0.6 -0.6 0.5 0.7 0.4 0.5 0.0 0.6 -0.6 0.4 -0.7 0.6 0.8 -0.4 0.4 -0.7 -0.2 1.0 0.8
HbA1C 0.1 0.1 0.5 -0.7 0.7 0.3 0.1 -0.0 0.0 0.1 -0.0 -0.2 0.3 -0.2 0.0 0.7 -0.4 0.2 0.2 0.2 0.2 -0.2 -0.0 -0.0 0.2
HDL Cholesterol 2.0 3.4 6.7 2.6 -2.4 -2.0 -2.0 2.3 -1.7 -1.2 -0.4 0.6 -0.9 -1.7 2.1 -1.7 1.5 1.9 -2.0 2.2 1.6 2.3 2.4 -1.3 -1.7
LDL Cholesterol 0.5 0.8 3.6 -0.0 0.1 0.4 -0.6 -0.6 1.2 0.8 0.7 -1.7 -0.7 -0.0 -0.9 0.4 -0.5 -1.9 0.5 -0.7 -1.3 -1.0 -1.1 0.9 0.6
Lupus 0.8 1.1 3.7 -0.7 1.2 1.2 0.5 -1.0 1.5 1.9 1.9 -0.1 1.3 0.9 -0.9 1.2 -0.4 -0.2 1.2 -0.9 -0.1 -1.1 -0.9 0.6 1.3
Neuroticism (2016) 0.3 0.5 2.8 0.1 -0.7 0.9 -0.1 -0.4 0.2 0.3 0.4 -1.0 -0.4 0.0 -0.7 0.1 -0.0 -1.5 0.7 -0.9 -1.7 -0.5 -1.0 0.1 0.3
Primary Biliary Cirrhosis 0.8 1.1 2.2 1.4 -1.1 -0.8 -1.0 1.5 -1.1 -0.2 0.1 -0.1 -0.3 -1.0 1.4 -1.4 1.3 0.7 -0.8 1.4 0.9 1.3 1.5 -0.5 -1.2
Rheumatoid Arthritis 0.6 0.8 2.4 -0.7 0.7 0.6 1.6 -0.8 0.6 0.4 0.7 1.4 0.8 1.3 -0.8 0.9 -0.4 0.7 0.9 -0.7 1.0 -0.7 -0.6 1.3 0.6
Schizophrenia (2014) 0.6 1.3 4.4 1.4 -0.2 -1.0 -1.8 0.9 -1.0 -0.5 -0.8 -2.1 -1.8 -1.1 1.2 -1.0 0.0 -1.1 -1.2 1.2 -0.9 1.0 0.7 -1.3 -0.5
Triglycerides 1.5 2.4 5.7 -1.4 1.1 1.3 0.3 -2.0 1.3 1.0 0.2 -2.3 -0.8 0.9 -2.0 1.3 -1.8 -2.1 1.3 -2.0 -1.9 -1.8 -2.4 1.3 1.4
Type 2 Diabetes (T2D) (2012) 0.6 0.7 1.6 0.3 -0.5 -1.0 0.2 1.0 -0.5 -0.8 -1.1 0.8 1.0 -0.6 1.0 -0.7 0.2 1.2 -0.9 0.8 1.0 1.2 1.2 -0.5 -0.8
Ulcerative Colitis 0.9 1.3 3.8 -0.5 1.1 2.0 1.4 -1.0 0.8 0.5 1.6 1.2 1.9 1.5 -1.0 0.9 0.3 0.4 1.8 -0.8 0.1 -1.2 -0.8 0.8 0.9
Blood Eosinophil Count 0.2 1.2 3.8 -1.8 1.9 0.8 0.8 -1.3 0.8 0.2 -0.7 -1.4 -0.4 1.1 -1.3 0.6 -1.5 -0.8 1.0 -1.4 -0.4 -0.8 -1.4 1.4 0.6
Blood Platelet Count 3.2 37.3 58.7 5.4 -5.4 -7.3 -7.3 7.0 -6.2 -5.8 -4.8 -2.5 -5.0 -7.7 6.9 -7.6 6.2 1.5 -7.5 7.0 1.2 7.2 6.4 -5.7 -6.5
Blood Red Count 0.0 0.3 2.1 0.4 0.5 0.1 -0.8 0.0 0.2 0.1 0.3 -1.4 -1.3 -0.5 0.1 0.2 -0.9 -1.0 -0.1 -0.1 -0.4 -0.5 -0.4 -0.4 0.2
Blood White Count 3.0 21.9 42.4 4.1 -4.3 -4.5 -6.1 5.1 -5.0 -5.2 -4.7 -3.6 -6.5 -6.0 5.1 -5.3 2.7 -0.4 -5.0 4.8 -0.0 5.0 4.3 -4.4 -4.9
Heel T-Score 0.1 0.7 4.5 -2.1 0.6 -0.1 0.3 -0.6 0.1 -0.0 -0.2 0.5 0.1 0.5 -0.7 0.3 0.3 -1.6 -0.3 -1.1 -2.0 -0.7 -1.0 -0.6 0.3
BMI 3.4 19.6 31.1 -4.9 5.0 4.9 3.7 -5.3 5.0 4.3 3.7 -1.0 2.5 4.8 -5.2 4.6 -3.4 -2.4 5.1 -5.5 -1.5 -5.6 -5.3 4.4 5.0
Height 1.0 18.7 50.6 1.3 -2.0 -5.7 -0.4 4.7 -3.7 -3.1 -3.3 3.7 0.6 -2.0 5.3 -3.1 1.2 7.1 -5.0 6.2 7.0 5.8 6.2 -2.6 -3.9
Waist Hip Ratio (WHR) 0.7 3.3 9.4 0.7 -0.4 -1.9 -1.2 1.7 -1.2 -2.6 -3.1 -1.2 -2.6 -2.5 2.1 -0.9 -1.7 1.7 -1.9 1.5 2.4 1.7 1.9 -1.3 -1.2
Systolic Blood Pressure 1.8 8.8 23.0 2.8 -1.4 -3.3 -4.8 3.3 -2.6 -2.2 -1.6 -3.6 -4.1 -3.5 3.0 -3.8 2.3 0.2 -3.1 3.6 0.6 3.4 2.9 -1.7 -2.8
Smoking Status 0.1 0.2 1.4 -0.4 1.2 0.3 0.6 -0.3 0.5 0.5 0.7 0.2 0.2 0.5 -0.2 0.4 -0.2 0.2 0.5 0.1 0.6 -0.4 -0.2 0.5 0.7
Allergy or Eczema 0.2 0.4 1.5 0.5 0.1 -0.4 -0.1 0.7 -0.5 -0.5 -1.0 0.7 0.7 -0.4 0.5 -0.7 0.6 -0.1 -0.4 1.2 -0.6 0.8 0.5 -0.7 -0.9
Cardiovascular Disease 0.6 1.8 6.9 1.8 -0.4 -1.1 -2.3 1.5 -1.0 -0.1 0.1 -1.7 -0.9 -1.4 1.3 -2.0 2.6 -0.3 -1.3 1.8 -0.3 1.0 1.0 -1.0 -0.9
Hypothyroidism (self reported) 0.1 0.2 1.2 -0.3 0.0 -0.5 -0.4 0.3 0.3 0.6 0.1 -1.1 -0.1 -0.1 0.3 -0.5 0.4 0.1 -0.4 0.7 0.3 0.1 0.2 -0.1 -0.0
Respiratory disease 0.1 0.3 0.8 -0.3 0.8 -0.8 0.3 -0.7 0.5 0.2 0.4 -0.7 -0.4 0.9 -0.4 0.4 -0.3 0.1 -0.3 -0.2 0.7 -0.4 -0.5 0.6 0.7
Type 2 Diabetes (T2D) (2018) 0.2 0.4 2.1 0.3 -0.8 -0.1 -0.5 0.3 -0.4 -0.9 -1.2 -0.7 -0.9 -0.4 0.0 -0.4 0.2 -1.4 -0.2 0.1 -1.4 0.0 -0.4 -0.4 -0.5
Lung FEV1/FVC ratio 1.1 5.7 12.7 2.5 -3.6 -1.3 -2.7 2.8 -2.6 -1.7 -1.5 0.9 -1.4 -2.7 2.8 -3.0 3.3 -0.1 -1.9 2.1 -1.1 2.6 2.6 -3.1 -3.1
Lung FVC 0.2 0.8 4.5 -2.1 0.7 1.7 0.9 -0.5 -0.5 -0.2 -0.4 -0.0 0.3 0.7 -0.3 0.9 -1.3 -0.9 1.1 -0.0 -1.0 -0.7 -0.8 -0.8 0.5
Neuroticism 0.3 0.7 4.1 -0.1 0.6 0.6 -0.5 -0.7 0.5 0.4 0.1 -2.0 -0.9 0.0 -0.7 0.4 -0.9 -1.5 0.4 -0.9 -1.4 -0.8 -1.2 -0.0 0.6
Chronotype (morning person) 1.6 3.8 8.9 -1.8 1.3 3.0 2.0 -1.9 2.1 1.9 2.3 0.9 2.1 1.6 -2.3 1.5 0.1 -1.0 2.8 -2.1 -1.2 -2.6 -2.0 2.1 1.8
Hair Pigment 0.0 0.2 0.5 0.7 0.2 -0.3 -0.6 0.1 -0.4 -0.3 -0.1 -0.6 -0.3 -0.1 0.0 -0.3 0.4 -0.5 -0.1 0.3 -0.7 0.5 0.1 0.5 -0.4
Tanning 0.3 3.2 5.4 -2.1 1.9 2.3 1.3 -2.0 1.6 2.0 1.7 0.2 0.9 2.0 -1.8 2.3 -1.8 -1.0 2.1 -2.0 -0.6 -2.2 -1.9 1.2 2.2
Hand grip strength (left) 0.1 0.1 0.5 -0.7 0.7 -0.2 0.2 0.1 -0.2 -0.2 -0.7 0.5 -0.0 0.6 -0.0 -0.1 -0.1 -0.5 -0.1 -0.0 -0.6 0.4 0.0 -0.0 -0.5
Number of treatments/medications taken 0.2 0.3 2.1 0.8 0.4 -0.5 -0.3 0.4 0.2 0.6 1.0 -0.2 0.8 0.1 0.2 -0.5 1.4 0.3 -0.3 0.9 0.4 0.2 0.1 0.3 0.3
Average weekly spirits intake 0.2 0.2 1.3 0.5 1.1 -0.5 -0.3 -0.3 0.7 0.7 0.8 -0.4 0.1 0.2 -0.3 0.4 -0.2 -0.0 -0.3 0.0 0.1 -0.4 -0.2 0.6 0.8
Sensitivity / hurt feelings 0.1 0.2 1.5 0.1 -0.1 0.9 -0.2 -0.1 0.0 0.3 0.4 -0.1 0.3 -0.2 -0.1 -0.1 0.5 -0.6 0.4 -0.5 -1.2 -0.7 -0.4 -0.5 0.1
Frequency of depressed mood in last 2 weeks 0.4 0.5 1.3 0.5 -0.8 -1.1 -0.5 0.8 -0.7 -0.3 -0.5 0.2 -0.7 -0.6 0.9 -0.4 0.0 0.9 -1.2 0.7 0.6 0.8 0.7 -0.9 -0.7
Hearing difficulty/problems: Yes 0.3 0.5 3.2 -0.9 0.2 0.0 1.1 -0.4 0.6 0.3 0.5 1.8 1.4 0.6 -0.5 0.3 0.6 1.0 0.3 -0.3 0.5 -0.3 -0.1 0.5 0.2
Relative age of first facial hair 0.2 0.5 1.6 -1.3 0.1 -0.1 0.3 -0.6 0.5 0.8 -0.4 -1.1 -1.1 0.3 -0.6 0.5 -1.2 -0.9 0.2 -0.3 -0.4 -0.3 -0.6 0.9 0.4
Other serious medical condition/disability diagnosed by doctor 0.3 0.4 2.7 0.7 0.1 -1.1 -0.8 0.0 0.2 0.6 0.5 -1.6 -0.7 -0.1 0.1 0.0 -0.3 0.5 -0.7 1.0 0.7 0.2 0.0 0.2 0.4
Ever used hormone-replacement therapy (HRT) 1.7 2.2 5.5 -1.7 2.1 0.9 2.0 -1.9 1.4 1.1 1.4 0.7 1.5 2.4 -1.7 1.6 -1.1 0.1 1.2 -1.2 0.4 -1.5 -1.5 1.6 1.5
Ever had hysterectomy (womb removed) 0.2 0.3 1.1 0.5 -0.9 -0.0 -0.4 0.4 -0.4 -0.3 -0.7 -0.2 -0.8 -0.1 0.1 -0.2 0.1 -0.9 -0.3 0.0 -1.0 -0.1 -0.2 -0.8 -0.2
Systolic blood pressure, automated reading 0.7 1.9 9.0 0.4 -0.4 -1.3 -3.0 1.0 -0.6 -0.6 0.3 -2.9 -2.3 -1.4 0.8 -2.0 1.6 -0.8 -1.2 1.3 -0.3 1.1 0.4 -0.5 -1.0
Eye problems/disorders: Diabetes related eye disease 0.9 1.0 2.9 1.7 -1.3 -0.1 -1.6 1.0 -0.6 -1.0 -0.1 -0.6 -1.6 -1.4 0.8 -0.9 0.8 -1.1 -0.4 0.8 -1.0 0.6 0.4 -1.1 -0.8
Angina 2.5 3.3 5.7 2.1 -1.1 -1.5 -2.3 2.2 -1.8 -2.3 -1.2 -0.1 -0.8 -2.0 2.2 -2.4 2.4 0.7 -1.8 2.4 0.5 1.9 2.1 -1.9 -1.8
Medication for hormone replacement therapy 0.8 0.9 4.0 -0.6 1.0 0.7 0.3 -0.8 0.9 0.9 0.8 -0.6 0.4 0.6 -1.1 0.3 0.6 -1.9 0.7 -1.1 -2.0 -1.1 -1.3 0.6 0.7
Vitamin and mineral supplements 0.1 0.1 0.8 -0.6 0.3 -0.2 -0.5 -0.2 0.1 -0.1 0.8 -0.7 -0.9 0.3 -0.0 0.2 -0.1 0.1 -0.3 -0.2 0.1 -0.2 -0.2 -0.1 0.3
Supplements: Zinc 0.3 0.3 2.9 0.4 0.2 -0.9 -0.9 -0.1 0.3 0.4 0.0 -1.7 -0.5 -0.5 0.2 -0.3 -0.3 0.5 -0.7 0.6 0.8 0.2 0.2 0.1 -0.1
Medication: Co-codamol 0.4 0.4 1.6 0.2 0.4 0.6 1.2 -0.5 0.4 0.1 0.5 1.2 1.2 0.7 -0.3 0.6 -0.0 0.9 0.5 -0.5 0.7 -0.5 -0.2 0.0 0.6
Medication: Metformin 0.4 0.6 3.0 0.4 -1.0 0.1 -1.1 0.5 -0.3 -0.7 -0.6 -1.4 -1.7 -0.9 0.3 -0.7 0.4 -1.1 0.0 0.2 -0.8 0.2 -0.0 -0.2 -0.6
Diabetes (father) 0.3 0.3 1.9 0.1 -0.6 0.9 0.2 -0.2 -0.0 0.1 -0.7 -0.3 -0.0 -0.1 -0.5 0.2 -0.0 -1.4 0.6 -0.8 -1.4 -0.6 -0.7 0.0 0.0
Diabetes (mother) 0.6 0.8 1.8 -0.5 0.9 0.6 1.3 -1.2 0.6 0.2 0.8 1.3 1.1 1.2 -0.9 1.3 -0.9 0.7 0.6 -1.1 0.4 -1.1 -0.9 0.3 0.7
Severe depression (siblings) 0.6 0.7 2.0 -0.8 1.1 0.6 -0.0 -0.7 0.8 1.4 1.4 -1.0 -0.3 0.8 -0.4 0.9 -0.9 0.7 0.6 0.0 0.8 -0.8 -0.6 0.4 1.2
Pack years adult smoking proportion 1.3 2.0 6.7 -0.7 1.1 1.8 1.5 -1.4 1.9 1.6 2.6 0.0 1.5 1.8 -1.4 1.0 0.0 0.6 2.1 -0.7 0.7 -1.2 -1.0 2.0 1.5
Impedance of leg (right) 15.2 73.5 114.5 7.4 -7.5 -8.7 -8.2 10.3 -9.7 -9.8 -9.6 0.1 -7.3 -10.0 10.7 -9.2 5.1 3.4 -9.6 9.7 2.6 10.3 10.2 -9.5 -9.6
Leg fat-free mass (left) 2.7 14.2 25.6 -4.1 4.0 3.0 4.7 -4.2 4.3 4.3 3.9 1.7 4.4 5.1 -4.1 4.1 -2.6 0.8 3.8 -3.6 1.1 -3.8 -3.4 4.3 4.0
Trunk fat percentage 0.2 0.9 2.6 -0.1 0.5 -1.1 -1.3 1.0 -0.6 -1.3 -1.6 -0.6 -1.0 -0.8 1.2 -1.2 0.2 0.7 -1.2 0.9 0.8 1.0 1.0 -1.0 -0.7
Hand grip strength (right) 0.1 0.3 2.4 -1.6 0.4 -0.6 -0.3 -0.1 0.2 0.1 -0.4 -0.6 -0.6 0.1 -0.4 -0.0 -0.4 -1.0 -0.2 -0.2 -0.9 0.2 -0.4 0.6 -0.1
Townsend deprivation index at recruitment 2.1 3.0 7.1 -1.9 1.6 1.1 1.6 -1.9 2.2 1.9 1.1 -0.5 0.3 2.1 -2.3 1.8 -1.7 -0.4 1.6 -2.0 0.1 -2.0 -2.1 2.7 2.0
Current tobacco smoking 0.3 0.5 1.7 -1.0 0.8 1.3 0.4 -0.4 0.4 0.3 0.5 -0.5 0.7 0.5 -0.6 0.1 0.4 -1.0 1.2 -0.4 -0.7 -0.7 -0.7 0.6 0.6
Average weekly fortified wine intake 1.9 2.3 4.2 1.7 -1.3 -1.6 -1.8 1.5 -1.8 -2.0 -1.1 -1.0 -2.1 -1.6 1.8 -1.4 0.7 0.4 -1.9 1.2 0.4 1.5 1.4 -2.0 -1.3
Maternal smoking around birth 0.3 0.4 1.5 0.0 0.1 1.2 0.3 -0.8 0.4 0.4 0.9 0.5 0.4 0.6 -0.6 0.7 -0.2 0.2 1.1 -0.9 0.1 -0.8 -0.6 0.5 0.8
Fed-up feelings 0.7 1.3 8.5 0.1 0.2 0.1 -1.1 -0.4 -0.2 -0.4 -0.8 -2.4 -1.4 -0.8 -0.5 0.2 -0.9 -2.9 -0.1 -0.4 -2.5 -0.6 -1.2 -0.2 0.4
Frequency of unenthusiasm / disinterest in last 2 weeks 0.4 0.5 2.9 0.5 -0.8 -0.1 -0.9 0.6 -0.6 -0.4 -1.1 -0.7 -1.7 -0.8 0.7 -0.4 -0.4 -0.2 -0.5 0.1 -0.3 0.4 0.3 -1.0 -0.7
Relative age voice broke 0.1 0.2 1.1 -0.7 -0.1 0.2 0.4 -0.2 0.4 0.1 -0.0 -0.4 -0.6 0.1 -0.2 0.5 -1.1 0.1 0.4 -0.3 0.1 -0.2 -0.2 0.7 0.3
Taking other prescription medications 0.3 0.5 2.4 0.9 -0.4 -0.6 -0.7 1.0 -0.4 -0.4 -0.0 -0.6 0.0 -0.5 0.7 -1.0 1.2 0.5 -0.4 1.5 0.4 0.7 0.8 -0.1 -0.4
Age when periods started (menarche) 1.1 2.7 4.5 0.7 -1.7 -2.0 -1.7 1.9 -1.5 -1.4 -2.0 -0.2 -1.8 -1.9 1.9 -2.1 1.4 0.7 -1.9 1.4 0.7 2.1 1.9 -1.3 -1.9
Bilateral oophorectomy (both ovaries removed) 0.7 0.8 1.9 0.4 0.5 -0.1 0.8 -0.9 1.0 1.3 1.0 -0.1 0.3 1.1 -0.6 1.2 -1.3 0.8 0.2 -0.5 1.4 -0.8 -0.7 0.7 1.4
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.4 3.3 -0.7 0.1 -0.2 -0.3 0.4 -0.6 -0.8 -1.0 0.4 -0.5 -0.2 -0.0 -0.4 0.6 -1.4 -0.1 0.0 -1.8 0.4 -0.0 -0.3 -0.7
Tinnitus: Yes, but not now, but have in the past 0.2 0.2 0.9 0.4 -0.1 -0.6 0.1 0.5 -0.3 -0.5 -0.9 0.2 0.0 -0.4 0.6 -0.1 -0.1 0.0 -0.6 0.5 -0.2 0.4 0.6 -0.5 -0.3
Qualifications: CSEs or equivalent 0.2 0.2 0.7 0.4 -0.1 0.1 0.6 0.2 -0.7 -0.9 -0.8 0.8 0.3 -0.3 0.3 0.2 -0.8 0.4 -0.0 0.1 0.3 0.4 0.3 -0.5 -0.3
Serious illness, injury or assault to yourself 0.7 0.8 1.6 1.2 -1.0 -1.0 -0.5 1.0 -0.9 -0.8 -0.5 0.4 -0.7 -0.8 1.1 -0.5 -0.2 1.2 -1.0 1.2 1.2 1.1 1.2 -0.6 -0.8
High blood pressure 0.2 0.7 3.2 1.0 0.4 -0.5 -1.5 0.7 -0.1 0.5 1.0 -1.4 -0.4 -0.7 0.5 -1.1 1.8 -0.3 -0.6 1.2 -0.2 0.2 0.2 -0.2 -0.2
Hayfever, allergic rhinitis or eczema 0.2 0.4 1.0 0.5 -0.1 -0.3 -0.1 0.8 -0.7 -0.6 -0.8 1.0 0.7 -0.5 0.5 -0.5 0.4 -0.1 -0.4 1.0 -0.7 0.8 0.6 -0.8 -0.9
Multivitamins +/- minerals 0.5 0.6 2.2 -0.1 0.1 1.0 1.1 -0.7 0.6 0.7 -0.1 0.7 1.5 0.5 -1.0 0.7 -0.7 -0.7 1.2 -0.7 -0.7 -0.5 -0.7 0.9 0.4
Stomach or abdominal pain in last month 0.3 0.4 3.8 0.7 0.2 -0.1 0.2 0.1 -0.4 -0.1 -0.0 0.1 0.3 -0.2 -0.0 -0.1 0.3 -1.7 -0.4 -0.1 -2.0 -0.2 -0.4 -1.0 -0.4
Supplements: Glucosamine 1.5 2.0 9.4 -1.4 1.5 0.9 1.1 -1.9 1.3 0.8 0.3 -1.3 -0.6 1.0 -1.2 1.8 -3.1 0.7 1.1 -1.4 1.6 -1.4 -1.4 1.5 1.6
Diverticular disease/diverticulitis (self-reported) 1.8 2.2 4.2 1.3 -1.0 -1.4 -1.2 1.8 -1.7 -1.8 -1.0 0.1 -0.2 -2.0 1.7 -1.8 1.7 0.1 -1.7 2.0 -0.0 1.7 1.6 -1.7 -1.7
Medication: Atenolol 0.8 1.0 3.3 1.3 -0.7 -0.9 -1.4 0.7 -1.0 -0.4 -0.4 -1.8 -0.9 -1.0 0.3 -1.0 0.9 -1.7 -1.0 0.3 -1.6 0.5 -0.1 -0.8 -0.6
Medication: Levothyroxine sodium 0.4 0.7 1.5 -0.8 0.6 0.9 0.7 -0.8 1.1 0.9 0.8 -0.3 0.9 0.7 -1.0 0.5 0.1 -0.6 1.1 -0.6 -0.4 -1.1 -0.9 1.2 0.8
Sitting height 0.5 3.4 11.4 -2.5 1.9 -0.2 3.4 -1.0 1.4 1.5 0.9 3.0 2.8 2.5 -0.9 1.8 -1.6 2.5 0.5 -0.3 2.6 -0.6 -0.2 1.5 1.0
Chronic bronchitis/emphysema (father) 1.7 2.0 4.1 -0.9 0.3 2.0 0.4 -1.5 1.7 1.0 1.1 -0.7 -0.7 0.9 -1.6 1.7 -1.9 -1.2 2.0 -1.5 -1.0 -1.7 -1.7 1.4 1.7
High blood pressure (mother) 0.1 0.2 0.9 -0.6 0.9 -0.2 -0.6 -0.0 -0.0 -0.9 -0.1 -0.7 -0.4 -0.6 -0.1 0.4 -0.8 -0.1 -0.1 -0.0 -0.1 -0.0 -0.1 0.3 0.2
Body mass index (BMI) 2.6 11.1 18.1 -3.5 3.7 3.7 2.7 -4.0 3.9 3.6 2.8 -0.6 2.0 3.7 -4.0 3.2 -2.2 -1.7 3.8 -4.1 -1.3 -4.3 -4.1 3.4 3.6
Impedance of leg (left) 13.7 66.6 102.4 7.1 -6.9 -8.3 -8.1 9.8 -9.3 -9.5 -9.0 -0.6 -7.1 -9.6 10.1 -8.7 4.8 2.9 -9.2 9.3 2.2 9.8 9.5 -9.2 -9.0
Leg predicted mass (left) 2.7 14.4 25.8 -4.1 4.1 3.1 4.8 -4.2 4.3 4.3 3.9 1.8 4.4 5.1 -4.1 4.1 -2.6 0.8 3.8 -3.7 1.1 -3.9 -3.4 4.3 4.1
Trunk fat mass 0.1 0.3 2.3 -1.3 1.5 -0.4 -0.0 -0.1 0.5 -0.2 -0.5 -0.1 0.2 0.5 0.1 -0.1 -0.4 0.8 -0.2 0.0 1.1 -0.0 0.1 0.1 0.3
Waist circumference 0.8 2.9 7.4 -2.5 2.7 1.1 1.7 -1.9 2.1 1.3 0.4 -0.5 0.9 1.9 -1.7 1.9 -2.3 0.2 1.4 -1.8 0.7 -1.8 -1.8 1.8 2.0
Number of incorrect matches in round 0.2 0.3 1.3 0.4 -0.1 0.2 0.5 -0.3 0.6 -0.2 1.0 1.2 0.7 0.7 -0.4 0.2 0.9 0.5 0.5 -0.4 0.5 -0.3 -0.2 0.5 0.3
Past tobacco smoking 0.2 0.3 1.4 0.7 -1.2 0.8 -0.1 0.4 -0.6 -0.5 -0.0 0.1 0.5 -0.5 0.1 -0.6 1.2 -0.1 0.5 0.2 -0.5 0.3 0.2 -0.0 -0.6
Alcohol usually taken with meals 0.5 0.8 1.9 0.4 -0.8 -1.1 -1.0 0.8 -1.1 -0.6 -1.4 -0.7 0.0 -0.9 0.5 -1.2 1.0 -0.7 -1.0 0.7 -1.3 1.1 0.5 -0.5 -1.3
Nervous feelings 0.1 0.1 0.8 0.2 0.2 -0.1 -0.5 0.1 -0.2 0.1 0.4 -0.9 0.3 -0.5 0.0 -0.3 0.5 0.1 -0.0 -0.1 -0.0 0.1 -0.0 -0.1 0.0
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.6 1.2 -0.5 0.9 0.9 1.1 -0.8 0.6 0.4 0.5 0.4 0.6 0.7 -1.0 1.1 -0.9 -0.2 1.0 -0.9 -0.2 -0.8 -0.9 0.9 0.7
Hearing difficulty/problems with background noise 1.6 2.6 5.7 -2.4 2.2 0.9 1.6 -2.0 2.2 1.2 1.3 0.3 1.3 1.8 -1.8 1.8 -1.3 0.1 1.3 -1.9 0.2 -1.8 -1.8 1.5 1.9
Hair/balding pattern: Pattern 2 0.1 0.2 0.8 0.1 -0.4 0.6 -0.1 0.3 -0.4 -0.5 -0.1 0.1 0.5 -0.1 0.4 -0.1 0.2 -0.6 0.1 -0.2 -0.9 0.1 0.2 -0.7 -0.2
Had menopause 0.9 1.2 2.6 -0.7 0.9 1.4 0.0 -1.1 0.8 0.9 1.0 -1.2 0.4 1.1 -1.5 0.0 1.2 -1.3 1.3 -1.0 -1.4 -1.3 -1.6 1.0 0.8
Had other major operations 3.6 4.3 8.1 -2.5 2.3 1.6 2.9 -2.0 2.1 2.8 1.9 1.3 2.4 2.5 -1.9 2.3 -1.8 1.3 2.1 -1.2 1.7 -1.9 -1.3 2.5 2.3
Forced vital capacity (FVC) 1.1 4.2 10.9 0.1 -0.9 -1.3 0.1 2.3 -2.6 -1.8 -1.6 2.0 0.5 -0.8 2.9 -1.1 -0.1 3.3 -1.6 3.1 3.0 2.6 3.0 -2.3 -1.8
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.5 1.9 -0.4 -0.1 -0.5 -0.1 0.7 -0.8 -1.2 -1.2 1.4 -0.3 -0.3 0.5 -0.6 0.9 -0.5 -0.5 0.6 -0.9 0.7 0.5 -0.9 -1.0
Ever unenthusiastic/disinterested for a whole week 1.1 1.4 4.2 1.4 -1.0 -1.1 -2.0 0.9 -1.1 -1.3 -1.0 -1.4 -1.4 -1.6 1.3 -1.1 0.2 0.4 -1.3 0.9 0.4 1.3 0.9 -1.3 -1.1
Qualifications: None of the above 0.4 0.8 4.0 0.8 0.7 -0.2 1.3 -0.2 0.5 1.2 1.6 2.0 1.5 1.1 -0.4 0.4 0.8 0.6 0.1 0.0 0.5 -0.3 -0.0 0.8 0.5
Financial difficulties in last 2 years 1.3 1.7 4.3 0.7 -1.2 -1.2 -0.4 1.4 -1.7 -1.1 -1.0 0.9 -0.2 -1.2 1.8 -0.8 0.1 2.1 -1.4 1.2 2.1 1.5 2.0 -1.2 -1.0
Mouth/teeth dental problems 0.7 1.1 2.2 0.9 -1.2 -0.6 -0.5 1.2 -1.1 -1.4 -0.9 0.7 -0.8 -0.8 1.3 -0.9 0.3 1.2 -0.7 1.4 0.8 1.3 1.5 -1.0 -1.3
Heart attack 1.5 1.9 5.0 1.6 -1.5 -0.3 -1.7 1.5 -1.5 -1.8 -0.8 -0.4 -1.0 -1.8 1.3 -1.9 2.2 -0.5 -0.8 1.1 -0.8 1.3 1.0 -1.5 -1.5
Allergy 0.5 1.1 2.9 -1.3 0.8 1.1 0.7 -1.1 1.0 1.1 1.1 -0.3 0.4 0.8 -1.2 1.0 -0.4 -0.7 1.0 -1.7 -0.6 -1.4 -1.3 1.0 1.2
Pain all over the body in last month 1.8 1.9 6.2 -1.3 1.0 0.2 1.7 -0.2 1.4 1.6 2.2 2.0 1.5 1.4 -0.3 0.9 0.5 2.5 0.8 0.5 2.5 -0.5 0.3 1.3 1.3
Diabetes (self-reported) 0.5 0.8 1.9 1.0 -1.1 -0.4 -1.3 0.7 -0.7 -1.3 -0.9 -0.7 -1.2 -0.9 0.5 -0.9 0.9 -1.4 -0.5 0.5 -1.2 0.5 0.0 -0.8 -0.8
Hayfever/allergic rhinitis (self-reported) 0.6 0.7 3.2 -1.8 1.7 0.4 0.5 -0.9 0.9 1.1 0.7 0.0 1.1 1.0 -0.7 0.8 -0.6 -0.1 0.4 -0.6 -0.1 -0.7 -0.9 0.2 0.9
Medication: Ramipril 0.1 0.2 2.2 0.3 0.5 -0.3 0.0 -0.2 0.2 0.1 -0.2 -0.7 -1.5 0.2 -0.0 -0.0 -0.5 0.3 -0.1 -0.0 0.6 -0.1 -0.3 0.1 0.2
Medication: Simvastatin 0.2 0.2 0.8 0.2 -0.5 -0.2 -0.4 -0.1 0.7 0.5 0.7 -0.6 0.5 0.0 -0.5 -0.1 0.8 -0.9 -0.1 -0.2 -0.8 -0.4 -0.7 0.2 0.4
Fluid intelligence score 0.2 0.4 2.1 0.5 -0.7 -0.6 -1.4 -0.1 -0.1 0.3 0.5 -1.5 -0.7 -1.2 -0.0 -0.4 0.6 -0.7 -0.6 0.7 -0.6 0.1 -0.3 -0.2 0.1
Illnesses of siblings 0.1 0.2 1.1 0.2 -0.4 -0.0 0.6 -0.0 -0.2 0.2 -0.6 0.4 0.6 0.3 0.2 0.1 -0.6 0.8 -0.0 -0.3 1.1 0.3 0.5 0.1 -0.4
Neuroticism score 0.5 0.9 4.5 -0.3 0.7 0.6 -0.5 -0.8 0.3 0.3 -0.5 -1.9 -0.9 -0.3 -0.8 0.4 -0.9 -2.1 0.4 -1.1 -2.1 -0.9 -1.3 -0.2 0.4
Weight 0.9 4.4 9.2 -3.0 3.0 1.4 2.5 -2.2 2.5 2.4 1.6 0.7 2.2 3.0 -2.0 2.1 -1.7 0.9 1.8 -1.9 1.2 -2.0 -1.8 2.3 2.2
Impedance of arm (right) 5.8 27.1 44.1 5.2 -5.2 -5.2 -4.5 6.3 -5.7 -5.8 -5.1 1.2 -3.1 -5.8 6.6 -5.1 3.0 3.4 -5.7 6.1 2.8 6.4 6.6 -5.8 -5.6
Arm fat percentage (right) 0.4 1.6 3.4 -1.8 1.8 1.5 0.8 -1.5 1.6 0.9 0.5 -0.2 0.7 1.4 -1.4 1.1 -1.1 -0.5 1.4 -1.8 -0.3 -1.7 -1.5 1.1 1.4
Trunk fat-free mass 1.8 10.1 19.8 -3.7 3.5 2.2 4.4 -3.3 3.3 3.8 3.4 2.3 4.1 4.5 -3.1 3.4 -2.1 1.5 2.9 -2.6 1.7 -2.8 -2.4 3.6 3.2
Hip circumference 0.5 2.0 5.3 -1.9 2.3 0.8 1.6 -1.5 1.7 1.6 1.0 0.7 1.8 2.1 -1.5 1.3 -0.7 0.1 1.1 -1.1 0.1 -1.3 -1.3 1.5 1.5
Time employed in main current job 0.9 1.0 5.5 -0.4 -1.1 -0.2 -1.1 0.8 -0.4 -0.6 -1.4 -1.3 -1.2 -1.4 0.2 -0.6 -0.1 -2.3 -0.3 0.1 -2.0 0.3 0.0 -0.2 -0.8
Alcohol intake versus 10 years previously 1.6 2.4 6.7 -1.1 0.8 1.3 2.4 -1.9 1.5 0.5 0.9 1.9 2.6 1.7 -2.0 1.5 -0.5 -0.3 1.6 -2.0 -0.2 -1.5 -1.6 2.0 1.1
Father’s age at death 0.2 0.3 1.7 0.2 -0.4 -0.3 -0.4 0.0 -0.6 -0.8 -0.8 -0.4 -1.3 -0.1 -0.0 0.0 -0.5 -0.8 -0.4 -0.3 -0.5 0.4 -0.1 -0.3 -0.3
Worrier / anxious feelings 0.1 0.3 1.4 0.0 1.2 0.8 0.3 -0.4 0.1 0.5 0.7 -0.2 0.3 0.3 -0.5 0.3 -0.1 -0.5 0.7 -0.7 -0.6 -0.7 -0.5 0.1 0.3
Frequency of tiredness / lethargy in last 2 weeks 1.2 1.9 4.4 -1.2 1.3 1.0 1.3 -1.6 1.7 1.6 2.0 -0.4 0.4 1.1 -1.1 2.0 -2.1 0.5 1.1 -1.4 0.9 -1.5 -1.3 1.2 1.9
Falls in the last year 1.5 2.0 5.8 -1.3 1.2 -0.1 2.4 -1.1 1.4 0.9 1.2 2.0 1.7 2.0 -0.9 1.7 -1.3 1.7 0.6 -0.6 2.1 -0.8 -0.4 1.6 1.3
Hair/balding pattern: Pattern 3 0.3 0.5 2.3 -0.8 0.7 -0.9 -0.7 -0.6 0.4 -0.2 -0.7 -1.5 -1.3 -0.3 -0.5 0.2 -1.1 -0.5 -0.5 -0.5 0.2 0.0 -0.7 0.4 0.3
Number of live births 1.4 2.0 4.8 -0.3 1.3 1.6 1.8 -0.6 1.2 2.0 2.2 1.2 2.2 1.6 -0.6 0.8 0.2 2.0 1.7 -0.1 2.1 -1.0 -0.0 1.5 1.1
Forced expiratory volume in 1-second (FEV1) 1.4 4.7 9.4 0.8 -1.8 -1.6 -0.5 2.5 -3.0 -2.2 -1.9 2.2 0.1 -1.4 3.0 -1.6 0.7 2.4 -1.9 3.1 1.8 2.9 3.1 -2.8 -2.4
Pulse rate 0.2 0.3 2.0 0.7 -0.5 0.3 -0.1 0.3 -0.1 0.0 0.7 0.4 -0.3 -0.1 0.7 0.2 -0.3 1.2 0.1 0.6 1.4 0.1 0.6 -0.6 0.1
Happiness 1.7 2.0 6.0 0.9 -1.9 -2.4 -1.0 1.4 -1.5 -1.9 -1.6 0.5 -1.1 -1.4 1.3 -1.4 0.9 0.6 -2.1 0.9 0.0 1.8 1.4 -1.0 -1.8
Noisy workplace 1.4 1.7 4.8 1.1 -1.8 -0.8 -1.0 1.6 -1.1 -1.3 -2.2 0.3 -0.3 -1.4 1.3 -1.7 1.2 -0.7 -1.2 1.1 -0.9 1.2 1.3 -1.5 -1.8
Qualifications: A levels/AS levels or equivalent 0.1 0.2 0.9 -0.0 -0.8 -0.4 -0.1 0.1 -0.4 0.1 -0.3 0.2 0.3 -0.4 0.6 -0.4 0.7 0.8 -0.7 -0.1 0.1 0.3 0.4 -0.9 -0.5
Serious illness, injury or assault of a close relative in last 2 years 0.9 1.0 2.0 0.8 -1.4 -0.9 -0.3 1.2 -1.3 -0.9 -1.3 1.1 -0.9 -0.4 1.1 -0.8 0.3 0.9 -0.9 1.2 0.5 1.2 1.4 -0.8 -1.1
Mouth/teeth dental problems: Dentures 1.2 2.1 3.4 -1.4 1.7 1.4 1.5 -1.4 1.5 1.5 1.3 -0.1 1.8 1.5 -1.8 1.3 -0.4 -1.0 1.5 -1.4 -0.8 -1.6 -1.7 1.7 1.7
Asthma 0.4 0.8 2.5 -0.7 1.2 0.0 1.0 -0.9 0.9 0.5 0.7 -0.4 0.5 1.3 -0.5 0.9 -1.2 1.0 0.4 -0.1 1.6 -0.6 -0.4 1.0 1.0
Medication: Ibuprofen (e.g. Nurofen) 0.1 0.1 0.7 -0.1 -0.3 -0.7 -0.1 0.2 -0.3 -0.4 -0.7 -0.4 -0.2 -0.8 0.1 -0.2 -0.4 -0.2 -0.5 -0.1 -0.0 0.5 0.2 0.2 -0.5
Medication: Cholesterol lowering 1.8 2.8 7.1 2.4 -1.7 -1.7 -2.1 1.9 -1.5 -1.6 -0.5 -0.1 -0.5 -1.7 1.8 -2.2 2.7 -0.4 -1.9 2.0 -0.5 1.5 1.5 -1.9 -1.5
Depression (self-reported) 0.4 0.4 1.6 0.9 0.0 0.5 0.7 -0.4 0.4 0.9 0.9 0.9 1.2 0.6 -0.2 0.4 0.1 1.1 0.6 0.0 1.2 -0.1 0.1 0.5 0.5
Medication: Lansoprazole 0.9 1.0 2.1 -0.4 1.1 0.8 1.0 -1.0 1.4 1.4 1.5 0.4 0.5 1.4 -1.1 1.1 -0.3 0.1 1.1 -0.5 0.3 -1.1 -1.0 1.2 1.2
Prospective memory result 2.1 2.6 4.9 -1.4 2.2 2.0 1.9 -1.9 1.4 0.8 1.5 0.2 1.8 1.9 -1.8 1.8 -1.1 -0.1 2.2 -1.6 0.6 -1.8 -1.7 1.8 1.7
Lung cancer (father) 0.4 0.5 3.1 0.4 -0.9 -1.8 -0.5 0.4 0.2 0.6 0.7 0.1 -0.6 -0.2 0.4 0.2 -0.5 1.0 -1.3 0.8 0.9 0.5 0.7 0.1 0.1
Illnesses of mother 0.4 0.5 2.1 -0.6 0.1 0.7 1.4 -0.7 0.5 1.3 0.1 1.1 0.8 1.3 -0.5 0.4 -0.1 0.2 0.8 -0.8 0.2 -0.3 -0.4 0.3 0.1
Forced expiratory volume in 1-second (FEV1), Best measure 1.0 3.2 6.5 0.6 -1.8 -1.1 -0.3 2.1 -2.4 -1.8 -1.5 1.9 0.3 -1.2 2.5 -1.2 0.5 2.0 -1.5 2.5 1.6 2.3 2.5 -2.4 -1.9
Pulse wave Arterial Stiffness index 1.8 2.1 4.7 -0.6 1.1 1.1 0.8 -1.8 1.7 1.5 1.7 -1.4 0.2 1.3 -1.9 1.4 -1.2 -1.2 1.3 -1.5 -0.2 -1.8 -2.2 1.9 1.7
Impedance of arm (left) 5.8 27.0 41.3 5.3 -4.8 -5.4 -5.1 6.3 -5.6 -5.9 -5.0 0.4 -3.5 -6.1 6.4 -5.3 3.2 2.9 -5.8 6.1 2.4 6.4 6.4 -5.5 -5.5
Arm fat mass (right) 0.9 3.7 7.4 -2.7 2.7 1.6 1.8 -2.2 2.4 1.9 1.2 0.0 1.4 2.5 -2.2 1.8 -1.5 -0.4 1.9 -2.3 -0.1 -2.3 -2.1 2.0 2.1
Trunk predicted mass 1.8 10.4 20.5 -3.8 3.5 2.2 4.5 -3.3 3.4 3.8 3.5 2.3 4.1 4.5 -3.2 3.5 -2.2 1.4 2.9 -2.7 1.6 -2.9 -2.5 3.7 3.2
Standing height 1.1 10.9 32.0 0.9 -1.2 -4.6 -0.0 3.4 -2.8 -2.4 -2.3 3.3 1.1 -1.3 4.0 -2.2 1.0 5.7 -4.0 4.4 5.4 4.5 4.8 -2.1 -2.8
Length of working week for main job 0.7 0.8 3.6 -0.9 0.7 -0.6 -0.6 -1.0 0.9 -0.1 0.2 -1.9 -1.2 -0.0 -1.1 0.4 -0.4 -1.3 -0.2 -0.7 -1.0 -0.7 -1.5 0.9 0.6
Exposure to tobacco smoke at home 0.4 0.4 1.7 0.8 -0.6 -0.7 -0.9 0.4 -0.0 -0.2 0.0 -0.7 -0.6 -0.8 0.1 -0.5 0.6 -1.3 -0.7 0.1 -1.2 0.3 -0.1 -0.6 -0.2
Breastfed as a baby 0.3 0.3 2.5 0.1 -0.4 -0.4 -1.0 0.5 -0.2 0.4 0.6 -0.1 -0.2 -0.8 0.4 -0.7 1.6 -0.2 -0.5 0.8 -0.5 0.1 0.1 -0.7 -0.1
Tense / ‘highly strung’ 0.5 0.8 2.6 -0.2 1.5 -0.2 -0.5 -0.9 0.6 0.7 0.8 -1.6 0.1 0.2 -1.2 0.3 0.3 -1.4 0.1 -0.6 -1.4 -0.8 -1.5 0.5 0.8
Seen doctor (GP) for nerves, anxiety, tension or depression 0.4 0.6 2.6 0.8 0.5 0.5 0.1 -0.3 0.8 1.2 1.0 -0.8 -0.7 0.7 -0.3 0.9 -1.6 0.7 0.8 0.6 1.1 -0.2 0.0 1.1 0.8
Hair/balding pattern: Pattern 4 0.3 0.7 4.0 0.0 -1.0 -0.4 -0.4 0.3 -0.7 -0.7 -0.9 0.5 0.3 -0.7 -0.0 -0.9 1.9 -1.6 -0.5 -0.0 -2.0 0.2 -0.2 -1.0 -0.6
Birth weight of first child 4.1 7.5 13.0 -2.5 2.5 3.6 2.3 -3.2 2.8 2.0 1.8 -1.4 0.8 2.5 -3.2 3.2 -3.1 -1.9 3.4 -3.6 -1.1 -3.6 -3.4 2.4 3.1
Peak expiratory flow (PEF) 0.4 0.8 3.2 -0.5 -0.6 -0.6 -0.2 0.7 -1.6 -1.0 -1.0 1.1 0.5 -0.6 1.2 -0.6 0.2 0.3 -0.9 1.1 -0.1 1.1 1.0 -1.8 -1.1
Pulse wave reflection index 4.7 5.8 13.5 -2.3 2.2 1.8 2.1 -3.1 2.3 1.6 1.2 -0.4 1.2 2.4 -3.3 2.6 -2.1 -2.8 1.9 -3.5 -2.2 -3.1 -3.7 2.2 2.4
Ever highly irritable/argumentative for 2 days 0.2 0.2 1.0 -0.2 0.1 0.3 -0.2 0.5 0.1 0.5 0.1 -0.2 0.1 -0.2 0.7 -0.2 -0.0 1.0 0.2 0.7 1.0 0.3 0.9 0.0 0.1
Loud music exposure frequency 0.7 0.8 3.1 0.4 -0.5 -1.3 -0.9 0.5 -0.9 -1.3 -1.4 -0.5 -1.8 -0.6 0.8 -0.7 -0.3 -0.6 -1.4 0.2 -0.4 0.9 0.4 -1.2 -0.8
Qualifications: O levels/GCSEs or equivalent 0.3 0.4 1.7 -0.9 -0.3 0.1 -0.7 0.1 -0.4 -1.2 -1.2 -0.9 -0.8 -0.8 0.5 -0.3 -0.2 -0.2 -0.3 -0.4 -0.5 0.2 0.1 -1.3 -0.4
Mouth/teeth dental problems: Bleeding gums 0.3 0.4 3.1 -0.2 0.2 -0.2 -1.3 -0.2 0.3 0.1 -0.2 -1.8 -1.2 -0.6 -0.0 -0.2 -0.1 -1.3 -0.4 -0.2 -0.8 -0.3 -0.5 -0.3 0.2
Blood clot in the leg (DVT) 2.1 2.8 7.0 1.8 -2.0 -1.2 -2.0 1.3 -1.7 -1.6 -2.2 -1.2 -2.1 -1.9 0.9 -1.8 1.5 -2.2 -1.3 0.9 -2.6 1.3 0.6 -1.4 -1.6
Medication: Paracetamol 0.4 0.7 2.6 -0.9 0.5 0.6 0.8 -0.4 0.9 1.6 0.7 -0.3 0.7 0.7 -0.3 0.9 -1.6 0.8 0.8 -0.1 1.0 -0.4 -0.1 0.8 0.8
Headache pain in last month 0.7 1.1 2.2 -1.0 1.0 1.3 0.4 -1.0 1.1 1.5 1.0 -0.9 0.8 0.6 -1.1 1.1 -1.1 -0.9 1.3 -0.8 -0.7 -1.2 -1.2 1.2 1.4
Medication for cholesterol, blood pressure or diabetes 1.7 2.9 13.3 -2.5 1.4 1.3 1.2 -2.0 1.7 1.4 -0.2 -1.3 -0.8 1.2 -1.8 2.2 -3.6 -0.6 1.5 -2.2 0.1 -1.5 -1.8 1.9 1.4
Glaucoma (self-reported) 1.5 1.8 3.8 1.9 -1.8 -1.4 -0.9 1.5 -1.7 -1.5 -0.9 1.2 -0.7 -1.1 1.2 -1.2 1.3 0.6 -1.2 1.5 0.2 1.7 1.4 -1.0 -1.7
Gout (self-reported) 0.4 0.5 1.7 0.6 0.6 1.3 0.0 -0.5 0.7 0.9 1.0 -0.8 0.4 0.5 -0.5 0.5 -0.4 0.4 1.3 0.1 0.6 -0.7 -0.4 1.1 0.9
Hypothyroidism/myxoedema (self-reported) 0.3 0.6 1.3 -0.9 0.7 0.7 0.7 -0.7 1.1 1.1 0.6 -0.6 0.8 0.7 -0.9 0.3 0.1 -0.3 0.8 -0.3 -0.2 -1.0 -0.7 1.1 0.7
Medication: Amlodipine 0.1 0.1 0.5 0.6 -0.1 0.3 -0.1 0.2 0.0 -0.2 -0.0 -0.0 -0.0 -0.0 0.4 -0.4 0.7 0.3 0.0 -0.2 -0.1 -0.1 0.3 -0.7 -0.3
Medication: Ventolin 100micrograms inhaler 0.3 0.4 1.8 -0.7 0.5 -0.4 0.4 -0.4 0.4 0.6 1.3 -0.1 0.5 0.7 -0.2 0.6 -0.6 1.2 0.0 0.7 1.3 0.0 -0.0 0.8 0.7
Birth weight 0.5 1.1 6.9 -0.8 -0.4 0.6 1.8 -0.0 -0.0 0.2 -0.1 2.6 1.7 0.9 0.3 0.8 -0.8 1.8 0.7 -0.2 1.7 0.1 0.7 0.2 0.1
Chronic bronchitis/emphysema (mother) 2.0 2.4 8.8 -0.8 1.6 0.7 2.2 -0.6 1.1 1.5 2.0 2.6 3.0 1.5 -0.6 1.0 0.3 2.4 1.1 -0.1 2.2 -0.7 0.2 1.6 1.2
High blood pressure (siblings) 0.3 0.4 2.1 -0.4 0.5 0.4 -0.4 -0.4 0.3 -0.5 0.5 -0.7 -0.9 0.1 -0.6 0.4 0.0 -1.5 0.4 -0.4 -1.4 -0.6 -1.0 0.0 0.6
Forced vital capacity (FVC), Best measure 0.7 2.4 7.0 0.1 -0.8 -1.1 0.1 1.7 -2.0 -1.4 -1.1 1.3 0.5 -0.6 2.2 -0.8 -0.2 2.4 -1.3 2.6 2.3 1.9 2.2 -1.8 -1.3
Body fat percentage 0.2 0.7 2.6 -0.4 0.7 -0.7 -1.4 0.8 -0.4 -1.2 -1.6 -0.9 -1.2 -0.8 0.9 -1.0 0.1 0.1 -0.8 0.5 0.4 0.6 0.6 -0.9 -0.5
Leg fat percentage (right) 0.2 0.8 3.3 -0.6 0.7 -0.3 -1.3 0.8 -0.6 -1.2 -1.8 -0.9 -1.5 -1.0 1.0 -1.1 0.2 -0.3 -0.6 0.3 0.0 0.4 0.6 -1.1 -0.7
Arm fat-free mass (right) 1.5 7.7 14.6 -3.5 3.5 1.7 3.4 -3.2 3.1 3.1 2.7 0.8 2.8 3.8 -3.1 2.9 -2.0 0.4 2.4 -2.6 0.7 -2.7 -2.7 3.3 2.9
Exposure to tobacco smoke outside home 0.6 0.8 2.9 -0.4 0.6 0.8 0.4 -1.0 0.8 0.5 0.1 0.1 -0.1 0.7 -1.2 0.6 0.1 -1.5 0.7 -1.3 -1.7 -1.1 -1.4 0.4 0.7
Comparative body size at age 10 0.5 1.3 5.1 -0.5 0.1 2.2 1.8 -0.9 0.4 0.5 1.1 1.9 2.1 1.3 -0.7 0.6 0.6 0.3 1.6 -1.5 0.1 -1.4 -0.7 -0.3 0.5
Number of full brothers 0.7 0.9 2.0 0.5 -1.4 -1.1 -0.5 1.0 -1.0 -0.8 -1.0 0.8 -0.4 -1.1 0.9 -0.8 0.3 1.0 -1.0 0.7 0.5 1.3 1.2 -0.4 -1.2
Worry too long after embarrassment 0.3 0.4 1.6 -0.0 0.1 0.6 -0.9 0.0 -0.2 -0.8 -0.2 -1.1 -1.2 -1.0 0.0 -0.1 -0.4 -1.1 0.1 -0.4 -1.3 -0.4 -0.4 -0.8 0.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.7 0.9 1.7 -0.4 1.3 0.2 0.4 -1.2 1.1 1.1 0.9 -1.0 -0.1 0.9 -1.2 1.1 -1.3 -0.5 0.5 -0.8 0.0 -0.9 -1.3 1.2 1.1
Wheeze or whistling in the chest in last year 3.0 5.3 8.4 -2.2 1.9 2.1 2.0 -2.8 2.8 2.9 2.7 -0.7 1.6 2.9 -2.7 2.6 -2.1 -0.4 2.5 -2.0 -0.1 -2.5 -2.6 2.9 2.7
Number of children fathered 0.3 0.4 1.5 -0.8 0.6 0.3 1.1 -0.1 0.3 0.2 0.4 0.8 0.8 0.7 -0.1 0.4 -0.5 1.2 0.5 -0.1 1.1 -0.1 0.4 0.7 0.4
Reason for reducing amount of alcohol drunk: Health precaution 0.8 0.9 3.4 0.8 -0.8 -1.3 0.2 0.9 -1.0 -0.8 -0.8 1.3 0.5 -0.6 0.5 -1.1 1.8 -0.3 -1.1 1.1 -0.8 1.0 0.8 -0.5 -1.2
Age at first live birth 4.0 7.1 11.0 2.0 -2.8 -2.7 -2.6 3.1 -3.3 -2.9 -3.1 -0.1 -1.4 -3.2 3.1 -3.0 2.2 0.5 -3.0 3.0 0.1 3.2 2.9 -3.1 -3.1
Pulse wave peak to peak time 2.9 3.4 7.2 1.0 -1.5 -1.6 -1.2 2.4 -2.1 -1.9 -2.1 1.3 -0.5 -1.8 2.4 -1.9 1.5 1.4 -1.8 2.1 0.4 2.4 2.7 -2.2 -2.2
Health satisfaction 0.5 0.7 2.0 -0.9 0.4 -0.2 0.2 -0.7 1.1 1.1 0.6 -0.9 -0.1 0.5 -0.8 1.0 -1.4 -1.0 0.1 -0.8 -0.9 -1.1 -1.0 0.8 1.1
Shortness of breath walking on level ground 0.5 0.6 3.3 -0.5 0.5 0.6 -0.8 -0.3 0.8 0.9 1.4 -1.8 -0.8 0.0 -0.5 0.1 0.2 -1.2 0.5 -0.1 -1.0 -0.8 -0.9 0.3 0.8
Qualifications: College or University degree 0.1 0.4 2.5 0.4 0.3 -0.2 -0.6 -0.3 0.7 1.5 1.6 -0.9 -0.1 0.5 -0.2 0.4 0.2 0.2 -0.1 0.4 0.3 -0.3 -0.3 0.0 0.8
Eye problems/disorders: None of the above 1.1 1.3 3.2 -1.8 0.6 1.5 0.4 -1.3 0.9 0.9 0.5 -1.4 0.0 0.7 -1.1 1.0 -1.4 -1.3 1.3 -1.7 -1.3 -1.3 -1.4 0.8 1.0
Mouth/teeth dental problems: Loose teeth 0.8 1.0 2.3 1.5 -0.9 -1.5 -1.1 0.8 -0.9 -0.6 -0.2 -0.1 -1.1 -0.5 1.1 -0.9 0.9 0.8 -1.5 1.1 1.0 1.0 0.9 -1.1 -0.6
Emphysema/chronic bronchitis 0.2 0.2 1.4 0.0 -0.2 -1.2 0.1 0.0 0.2 0.4 1.0 0.1 -0.4 0.0 -0.0 0.2 0.1 0.2 -0.9 -0.1 0.5 -0.1 -0.2 -0.1 0.2
Medication for pain relief, constipation, heartburn 0.1 0.1 0.5 0.3 -0.5 0.3 -0.1 -0.1 -0.2 -0.5 -0.1 0.7 -0.1 -0.0 -0.1 0.0 0.3 -0.3 0.0 -0.2 -0.4 -0.2 -0.1 -0.6 -0.2
Neck or shoulder pain in last month 2.0 2.8 6.5 -1.5 2.1 1.2 1.0 -2.1 2.0 1.7 1.1 -1.6 0.4 1.5 -1.9 1.9 -2.5 -0.9 1.5 -1.4 0.2 -2.0 -2.1 2.1 2.1
Medication: Blood pressure 1.0 1.8 8.8 1.9 -0.9 -0.8 -1.4 1.6 -1.2 -1.0 0.0 0.2 -0.1 -1.3 1.5 -2.1 3.0 -0.1 -1.0 1.8 -0.6 1.2 1.2 -1.4 -1.3
Angina (self-reported) 2.9 3.9 7.6 2.3 -1.3 -1.6 -2.3 2.4 -2.0 -2.5 -1.4 0.3 -0.8 -2.1 2.3 -2.5 2.7 0.6 -1.9 2.6 0.3 2.1 2.2 -2.1 -2.0
Migraine (self-reported) 0.3 0.4 2.2 -0.7 0.4 0.8 0.2 -0.1 0.4 0.2 0.4 -0.3 0.8 0.0 -0.8 0.0 0.5 -1.2 0.9 -0.2 -1.5 -0.4 -0.5 1.2 0.2
Medication: Ibuprofen 0.1 0.1 0.5 -0.3 0.1 -0.5 0.7 -0.3 0.1 0.1 -0.0 0.5 0.7 0.0 -0.3 0.5 -0.6 0.2 -0.3 -0.4 0.3 -0.0 -0.3 0.3 0.1
Medication: Allopurinol 0.9 1.2 3.4 -0.6 1.0 1.9 0.7 -1.1 1.1 1.2 1.1 -0.3 0.7 1.1 -1.1 1.2 -1.1 0.1 1.9 -0.7 0.1 -1.3 -1.0 1.2 1.2
Medication: Omeprazole 0.7 0.9 3.2 1.1 0.3 -0.5 -0.9 1.0 -0.9 -0.1 0.1 -0.6 -0.4 -0.6 1.4 -1.1 0.9 0.9 -0.7 1.8 0.8 1.1 1.2 -1.3 -0.8
Medication: Seretide 50 evohaler 0.3 0.4 1.1 -0.6 0.4 0.1 0.3 -0.7 0.7 0.5 0.3 -0.5 -0.4 0.6 -0.6 0.8 -1.1 -0.4 0.1 -1.1 -0.6 -0.8 -0.7 0.0 0.7
Mean time to correctly identify matches 0.3 0.5 1.6 -0.1 0.1 0.3 0.8 -0.1 0.4 0.9 1.2 1.1 1.0 1.0 -0.0 0.6 -0.0 1.3 0.4 -0.3 1.2 -0.2 0.2 0.3 0.7
Heart disease (mother) 0.9 1.1 3.1 1.2 -1.5 -0.9 -1.4 1.3 -1.0 -1.5 -0.3 -0.0 -0.7 -1.8 1.1 -1.0 0.7 0.4 -1.0 1.3 0.0 1.1 1.1 -0.8 -1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.5 0.6 3.0 -0.4 0.2 -0.4 -0.0 0.5 -1.6 -1.7 -1.5 0.8 0.4 -0.8 0.6 -0.3 0.1 -0.3 -0.8 -0.2 -1.0 0.6 0.4 -1.3 -0.7
Whole body fat mass 0.1 0.4 3.1 -1.6 1.8 -0.0 0.1 -0.5 0.7 0.1 -0.4 -0.3 0.2 0.7 -0.3 0.2 -0.6 0.2 0.1 -0.5 0.5 -0.4 -0.4 0.4 0.6
Leg fat mass (right) 0.2 0.8 4.5 -2.1 2.1 0.7 0.5 -0.8 1.0 0.4 -0.3 -0.3 0.2 1.0 -0.6 0.5 -0.8 -0.3 0.7 -1.1 0.0 -1.0 -0.8 0.5 0.9
Arm predicted mass (right) 1.4 7.1 14.1 -3.3 3.3 1.7 3.4 -3.0 2.9 3.0 2.6 1.1 2.9 3.8 -2.9 2.7 -1.6 0.3 2.3 -2.6 0.6 -2.6 -2.6 3.2 2.7
Pulse rate, automated reading 0.5 1.6 5.0 2.2 -1.4 -0.3 -1.2 1.3 -1.1 -1.1 0.4 0.0 -0.8 -0.9 1.7 -1.0 0.7 1.8 -0.6 1.7 1.9 1.2 1.6 -1.2 -1.0
Alcohol intake frequency. 1.3 2.9 6.5 -1.4 0.6 1.6 1.5 -2.0 1.4 1.2 0.5 -0.4 0.4 1.5 -2.3 1.9 -1.9 -2.4 1.6 -2.6 -2.3 -2.0 -2.5 1.3 1.4
Comparative height size at age 10 0.9 4.9 21.3 0.7 -0.9 -2.5 0.3 1.9 -1.4 -1.1 -0.4 3.1 2.0 -0.5 2.3 -0.9 0.2 4.6 -2.1 2.9 4.2 2.7 3.1 -1.0 -1.5
Number of full sisters 0.1 0.1 0.6 0.3 -0.6 -0.7 0.3 -0.2 0.0 -0.1 -0.4 0.8 -0.1 0.6 -0.4 -0.0 0.4 -0.0 -0.3 -0.3 -0.1 -0.0 -0.3 0.5 -0.1
Suffer from ‘nerves’ 0.7 1.0 2.7 -1.0 0.9 0.7 0.0 -1.1 1.2 1.1 1.0 -1.6 -0.2 0.4 -1.3 0.9 -0.9 -0.7 1.1 -1.0 -0.3 -1.1 -1.3 1.4 1.3
Overall health rating 0.2 0.3 1.5 0.5 -0.2 -1.2 -0.6 0.3 0.0 -0.0 0.2 -1.2 -1.1 -0.5 0.3 -0.0 -0.6 0.2 -0.8 0.8 0.3 0.5 0.1 0.1 0.2
Chest pain or discomfort 0.4 0.6 2.2 -0.0 -0.6 -0.8 0.1 0.7 -0.4 0.1 0.5 1.3 0.5 0.0 0.9 -0.2 0.3 1.4 -0.7 0.9 1.5 0.6 1.0 -0.8 -0.4
Had major operations 0.5 0.6 1.7 0.4 -0.2 1.1 -0.0 -0.6 1.0 0.9 1.3 -0.7 -0.8 0.4 -0.6 0.8 -0.7 -0.5 1.0 -0.7 -0.3 -1.1 -0.7 0.8 1.0
Age at last live birth 5.8 8.4 12.2 2.9 -2.9 -3.1 -2.5 3.4 -3.5 -3.1 -2.7 0.4 -1.3 -3.2 3.2 -3.5 3.3 0.4 -3.3 3.3 0.2 3.5 3.2 -3.1 -3.4
Family relationship satisfaction 0.6 0.8 2.8 0.6 -1.7 -1.2 -0.5 0.7 -1.0 -1.2 -0.6 0.7 -0.4 -1.0 0.6 -0.8 1.0 -0.2 -1.1 0.0 -0.9 1.0 0.5 -0.8 -1.2
Leg pain on walking 1.0 1.3 2.5 -1.1 1.4 0.9 1.5 -1.0 1.3 1.5 1.6 -0.2 0.9 1.6 -0.8 1.2 -1.1 0.6 1.1 -0.8 0.9 -1.1 -0.7 1.2 1.5
Qualifications: NVQ or HND or HNC or equivalent 1.5 1.8 8.5 -2.4 1.4 1.3 1.2 -1.4 1.2 1.0 0.1 -0.9 -0.4 1.2 -1.0 1.6 -2.9 0.3 1.5 -1.4 0.9 -1.3 -0.9 1.4 1.3
Commuting to job workplace: Car/motor vehicle 1.4 1.6 3.1 -1.0 1.5 1.4 1.4 -1.1 1.3 1.4 1.4 0.9 1.4 1.8 -1.1 1.4 -0.6 0.1 1.5 -1.3 0.1 -1.3 -1.0 1.2 1.5
Illness, injury, bereavement, stress in last 2 years 0.5 0.6 1.7 -0.2 0.8 0.4 -0.3 -0.7 1.0 0.3 1.1 -0.7 0.7 0.3 -1.0 0.2 0.7 -1.2 0.5 -0.4 -1.3 -0.7 -1.2 0.4 0.7
Medication: Aspirin 0.2 0.3 2.2 0.2 -0.2 -0.5 -0.7 0.5 -0.4 -0.8 -0.1 -0.0 0.1 -0.5 0.3 -0.7 1.5 -0.0 -0.5 0.7 -0.3 0.2 0.2 -0.3 -0.1
Supplements: Vitamin C 0.9 1.0 2.8 1.0 -0.9 -0.8 -0.3 1.0 -1.4 -1.3 -1.7 0.8 0.1 -0.8 1.0 -1.2 1.0 0.4 -1.0 0.9 -0.1 1.2 1.0 -1.3 -1.5
Knee pain experienced in last month 2.4 3.7 6.7 -2.3 2.0 0.8 2.3 -2.5 2.2 1.3 2.0 0.4 1.4 2.1 -2.0 2.6 -2.5 0.4 1.4 -2.1 1.1 -2.0 -2.1 2.0 2.5
Hypertension (Self-reported) 0.2 0.6 3.9 1.1 0.2 -0.1 -1.2 0.4 0.2 0.9 1.3 -0.9 0.1 -0.4 0.1 -0.9 2.0 -0.7 -0.2 0.8 -0.8 -0.1 -0.1 -0.1 -0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.9 1.0 2.2 0.6 -0.3 -1.2 -1.1 0.8 -1.1 -0.6 -1.3 -0.7 -0.4 -0.9 0.5 -1.4 1.1 -1.5 -1.2 0.9 -1.2 1.0 0.2 -1.2 -1.4
Illnesses of father: Heart disease 1.6 2.2 5.3 1.4 -1.1 -0.7 -1.6 1.8 -1.4 -1.0 -0.5 -0.0 -0.4 -1.6 2.0 -2.1 2.2 1.4 -1.2 2.3 1.0 1.5 1.8 -1.8 -1.5
Illnesses of siblings: Diabetes 0.3 0.3 1.6 0.4 -0.5 -0.2 0.4 -0.1 0.3 0.9 0.9 0.7 0.0 0.4 0.1 0.7 -0.8 1.3 0.0 0.3 1.0 0.1 0.3 0.5 0.4
Smoking status: Previous 0.3 0.4 2.0 0.1 1.0 -1.4 -0.1 -0.1 0.3 0.3 0.1 0.1 -0.7 0.3 0.4 0.5 -1.3 0.9 -1.1 0.3 1.2 0.3 0.3 -0.3 0.3
Forced expiratory volume in 1-second (FEV1), predicted 2.2 4.6 10.4 0.3 -1.2 -3.0 0.5 2.2 -2.4 -2.1 -1.7 3.1 1.5 -1.0 2.4 -1.4 1.2 3.2 -2.7 2.1 2.4 2.7 2.9 -1.6 -2.0
Whole body fat-free mass 2.2 12.4 23.7 -4.0 3.9 2.6 4.7 -3.8 3.8 4.1 3.8 2.0 4.3 4.9 -3.6 3.8 -2.3 1.1 3.4 -3.1 1.4 -3.4 -3.0 4.0 3.7
Leg fat-free mass (right) 3.3 17.6 31.0 -4.4 4.5 3.4 5.1 -4.8 4.8 4.8 4.5 1.7 4.8 5.6 -4.7 4.7 -2.8 0.7 4.2 -4.0 1.0 -4.3 -4.0 4.8 4.6
Arm fat percentage (left) 0.5 2.1 4.6 -1.9 2.1 1.6 0.7 -1.7 1.9 1.1 0.7 -0.7 0.6 1.5 -1.7 1.2 -1.1 -0.8 1.6 -2.0 -0.4 -1.9 -1.7 1.4 1.7
Average weekly red wine intake 2.3 3.4 5.4 2.2 -1.6 -2.1 -2.0 2.2 -2.0 -1.9 -1.7 -0.6 -1.1 -2.0 2.0 -2.3 2.0 0.4 -2.1 2.1 -0.1 2.3 2.0 -1.7 -2.1
Handedness (chirality/laterality): Left-handed 1.5 1.8 5.1 -0.7 0.6 1.0 1.4 -1.5 1.5 2.3 1.8 0.2 0.7 1.8 -1.4 1.8 -1.7 0.5 1.3 -1.3 0.7 -1.3 -1.1 1.6 1.7
Mood swings 1.1 2.0 4.2 -1.1 1.3 1.4 0.9 -1.7 1.1 0.9 0.2 -1.0 -0.2 1.1 -1.9 1.4 -1.5 -1.9 1.4 -1.8 -1.7 -1.8 -2.1 1.4 1.3
Loneliness, isolation 1.1 1.6 4.1 0.7 -1.4 -1.2 -1.5 1.1 -1.4 -1.8 -2.0 -0.3 -1.8 -1.5 1.2 -1.1 0.1 -0.1 -1.4 0.9 -0.6 1.2 0.9 -1.6 -1.3
Long-standing illness, disability or infirmity 0.1 0.2 1.3 0.7 -0.1 -0.9 0.0 0.2 0.2 0.3 0.8 0.1 0.7 0.4 0.0 0.1 0.4 0.5 -0.4 1.1 0.2 0.4 0.3 0.3 0.3
Ever had bowel cancer screening 0.4 0.5 2.0 -0.4 0.3 0.6 0.6 -0.6 0.8 1.4 1.2 0.1 0.4 0.8 -0.6 0.8 -0.7 0.2 0.7 -0.5 0.2 -0.8 -0.4 0.8 0.8
Diabetes diagnosed by doctor 0.5 0.9 3.1 1.3 -0.8 -0.5 -1.2 0.6 -0.7 -1.4 -0.9 -0.6 -0.9 -0.8 0.3 -0.9 1.2 -1.7 -0.6 0.5 -1.5 0.4 -0.2 -0.8 -0.7
Ever had stillbirth, spontaneous miscarriage or termination 3.3 3.5 8.3 -0.6 2.3 1.5 1.7 -2.2 2.1 2.9 2.7 -0.1 2.2 2.6 -1.9 1.9 -1.1 0.1 1.9 -1.6 0.7 -1.7 -1.8 2.2 2.1
Friendships satisfaction 1.0 1.2 3.2 0.3 -1.8 -1.4 -1.0 0.8 -1.4 -1.2 -1.3 0.4 -1.1 -1.2 0.9 -0.9 0.4 -0.6 -1.4 0.0 -1.1 1.1 0.5 -1.3 -1.6
Qualifications: nursing, teaching 0.8 1.3 3.8 -1.0 0.6 0.9 1.9 -0.9 0.6 1.5 0.6 1.4 2.0 1.8 -0.5 1.2 -1.0 1.6 0.9 -0.5 1.6 -0.7 -0.3 0.3 0.8
Commuting to job workplace: Walk 1.3 1.3 3.2 1.1 -1.0 -1.3 -1.8 1.1 -0.9 -0.8 -0.5 -1.6 -1.8 -1.5 1.3 -1.2 0.5 0.0 -1.4 1.3 0.4 1.1 1.0 -1.2 -0.9
Eye problems/disorders: Cataract 0.5 0.6 1.4 0.6 -0.3 -0.5 -0.2 0.9 -0.6 -0.7 -0.7 1.1 0.4 -0.5 0.9 -0.5 0.7 1.2 -0.6 1.1 1.0 0.7 1.1 -0.6 -0.6
Mouth/teeth dental problems: Mouth ulcers 0.6 1.0 2.3 0.8 -0.6 -1.4 -0.7 1.1 -1.2 -0.7 -1.1 0.2 -0.2 -1.1 1.1 -1.1 0.8 -0.1 -1.5 0.8 -0.5 1.1 1.0 -1.4 -1.1
Medication for cholesterol 0.2 0.4 1.5 -0.4 -0.6 -0.5 0.2 0.2 -0.7 -1.2 -1.2 0.4 -0.2 -0.4 0.6 -0.0 -0.8 0.6 -0.5 0.3 0.8 0.6 0.7 -0.5 -0.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 2.2 2.5 7.2 -2.7 2.4 0.8 1.7 -1.8 1.7 1.4 0.9 -0.8 0.8 1.7 -1.3 2.0 -2.4 0.4 1.0 -1.2 1.1 -1.6 -1.7 1.1 2.1
Back pain experienced in last month 2.2 3.2 6.5 -1.7 1.8 2.1 2.0 -1.8 2.1 2.6 2.0 0.8 2.1 1.8 -1.7 2.0 -1.5 0.0 2.1 -1.8 0.2 -2.0 -1.5 1.7 1.9
Mineral and other dietary supplements 0.2 0.2 1.3 -0.4 -0.0 0.7 0.1 -0.1 0.4 0.2 1.1 1.1 0.8 0.4 -0.2 0.2 0.7 -0.1 0.5 -0.2 -0.4 -0.3 -0.1 -0.1 0.2
Breast cancer (self-reported) 1.8 2.2 4.4 1.4 -2.1 -1.1 -1.3 1.8 -1.7 -1.4 -1.1 0.5 -0.9 -1.3 1.8 -1.5 1.0 1.4 -1.2 1.8 1.3 1.8 2.0 -1.4 -1.7
Asthma (self-reported) 0.3 0.7 1.9 -0.5 1.2 0.1 1.0 -0.9 0.9 0.5 0.7 -0.3 0.5 1.3 -0.6 0.8 -0.9 0.9 0.4 -0.2 1.4 -0.7 -0.4 0.9 1.0
Osteoporosis (self-reported) 0.3 0.4 1.7 -0.3 -0.6 0.3 0.3 -0.1 -0.7 -0.5 -1.3 0.2 -0.1 0.1 -0.1 0.3 -0.8 -1.2 -0.0 -0.8 -1.2 -0.1 -0.4 -0.9 -0.2
Osteoarthritis (self-reported) 1.0 1.3 4.1 -0.5 1.0 0.7 0.2 -0.8 1.6 1.0 1.9 -1.2 -0.4 0.6 -0.5 1.2 -1.9 1.1 0.9 0.2 2.0 -0.9 -0.6 1.0 1.7
Medication: Aspirin 0.1 0.2 1.9 0.0 0.0 -0.3 -0.4 0.3 -0.1 -0.6 0.2 0.0 0.3 -0.3 -0.0 -0.5 1.4 -0.3 -0.2 0.4 -0.5 -0.1 -0.1 -0.0 0.1
Medication: Gliclazide 0.6 0.7 2.2 0.4 -0.4 1.1 0.4 -1.2 0.7 0.3 0.5 -0.5 0.1 0.8 -1.2 0.8 -0.4 -1.0 1.0 -1.2 -1.3 -1.1 -1.5 0.6 0.7
Illnesses of father: None of the above (group 1) 1.0 1.3 2.7 -0.8 1.2 -0.2 1.4 -1.5 1.1 1.2 0.8 0.7 1.3 1.5 -1.5 1.4 -0.8 -0.3 0.4 -1.6 0.1 -1.1 -1.2 1.6 1.2
Smoking status: Current 0.6 0.9 2.9 -1.4 0.9 1.7 0.6 -0.7 0.7 0.5 0.5 -0.5 0.7 0.7 -1.1 0.4 0.2 -1.4 1.5 -0.9 -1.0 -1.1 -1.1 0.9 0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.3 0.9 -0.5 -0.7 0.7 -0.0 0.3 -0.8 -0.2 -0.1 0.7 0.9 0.1 0.4 -0.2 0.6 0.2 0.3 0.8 -0.2 0.2 0.3 -0.9 -0.5
Whole body water mass 2.3 13.2 25.1 -4.1 3.9 2.7 4.8 -4.0 4.0 4.3 3.9 2.1 4.5 5.0 -3.8 3.9 -2.3 1.0 3.5 -3.3 1.2 -3.5 -3.1 4.1 3.8
Leg predicted mass (right) 3.4 18.2 31.7 -4.4 4.5 3.5 5.2 -4.8 4.9 4.9 4.6 1.7 4.9 5.6 -4.7 4.7 -2.9 0.6 4.3 -4.1 0.9 -4.4 -4.0 4.8 4.7
Arm fat mass (left) 1.1 4.6 9.0 -2.9 3.0 1.8 1.8 -2.5 2.7 2.1 1.5 -0.2 1.5 2.6 -2.5 2.0 -1.6 -0.5 2.1 -2.6 -0.0 -2.5 -2.4 2.4 2.4
Number of self-reported non-cancer illnesses 0.4 0.6 2.4 0.1 1.1 -0.3 -0.3 -0.5 0.9 1.4 1.5 -1.5 0.5 0.6 -0.7 0.1 0.6 -0.5 0.1 0.7 -0.0 -0.6 -0.8 0.8 1.1
Average weekly champagne plus white wine intake 0.4 0.5 1.9 0.1 0.1 -0.5 0.3 0.7 -0.8 -0.6 -0.9 0.8 0.2 -0.0 0.9 -0.2 -0.2 1.4 -0.6 0.8 1.1 0.7 1.0 -0.6 -0.6
Miserableness 0.5 0.9 6.1 -0.4 0.3 -0.3 -0.3 -0.5 0.1 -0.3 -0.9 -1.1 -1.0 -0.2 -0.8 0.3 -0.7 -2.4 -0.3 -1.2 -2.5 -0.6 -1.2 -0.1 0.2
Guilty feelings 0.2 0.3 1.5 -0.0 -0.7 0.6 0.1 -0.3 0.1 -0.3 -0.7 -0.3 -0.3 -0.3 -0.5 0.2 -0.3 -0.9 0.6 -0.9 -1.2 -0.3 -0.5 0.1 0.0
Wears glasses or contact lenses 2.0 2.3 5.1 -1.8 2.3 0.2 0.8 -2.0 2.0 1.7 0.8 -1.4 0.6 1.9 -1.9 1.5 -1.3 -0.7 0.7 -1.6 -0.1 -1.6 -2.1 1.6 2.0
Ever taken oral contraceptive pill 0.2 0.2 1.3 -0.2 0.4 -0.4 0.3 -0.4 0.4 0.3 0.4 0.6 1.2 0.3 -0.5 0.3 0.1 0.0 -0.0 -0.0 -0.2 -0.0 -0.4 0.7 0.2
Hearing aid user 0.3 0.3 2.0 -0.5 0.4 -0.2 0.4 -0.1 -0.1 -0.2 0.6 0.9 1.2 0.3 0.2 -0.1 0.8 1.4 -0.2 0.2 1.2 0.1 0.2 -0.1 0.1
Mother’s age at death 0.1 0.2 0.6 -0.7 0.5 -0.3 0.3 0.5 -0.4 -0.6 -0.6 0.8 0.3 -0.2 0.4 -0.2 0.0 0.3 -0.2 0.4 0.2 0.3 0.6 -0.1 -0.5
Financial situation satisfaction 1.0 1.2 4.3 -0.1 -1.2 -1.3 -0.7 1.2 -1.4 -1.4 -2.1 0.4 -0.6 -1.0 1.3 -1.0 0.1 0.3 -1.4 0.8 0.3 1.3 1.3 -1.2 -1.3
Tinnitus: Yes, now most or all of the time 0.2 0.2 1.4 0.3 -0.2 -0.3 -0.7 -0.3 0.2 -0.3 -0.2 -1.1 -1.2 -0.2 -0.3 0.0 -0.3 -0.9 -0.3 -0.2 -0.5 -0.4 -0.6 0.1 0.3
Commuting to job workplace: Public transport 0.4 0.5 2.4 0.8 -0.7 -1.5 -0.4 0.5 -0.6 -0.0 -0.7 -0.3 -0.4 -0.4 0.5 -0.8 0.5 0.5 -1.3 1.0 0.5 0.9 0.6 -0.1 -0.9
Eye problems/disorders: Glaucoma 2.0 2.3 7.4 2.7 -2.3 -1.9 -0.9 1.7 -1.5 -1.3 -0.4 1.6 -0.8 -1.3 1.4 -1.2 1.5 1.1 -1.6 1.7 0.8 1.7 1.7 -1.1 -1.6
Medication: Blood pressure 0.3 0.5 1.9 0.1 0.6 0.7 -0.0 -0.5 0.9 1.4 1.3 -0.7 0.0 0.7 -0.6 0.6 -0.4 0.6 0.7 -0.3 0.6 -0.8 -0.6 0.8 0.8
Pain type(s) experienced in last month: Hip pain 0.2 0.3 1.1 -0.2 -0.1 -0.3 0.6 -0.5 0.7 1.0 0.9 -0.0 1.0 0.6 -0.5 0.4 0.0 -0.6 -0.1 -0.1 -0.2 -0.3 -0.7 0.0 0.4
Supplements: Fish oil (including cod liver oil) 1.5 2.0 4.4 1.5 -0.9 -2.1 -1.5 1.1 -1.5 -1.2 -1.7 -1.5 -2.0 -1.6 1.5 -1.2 -0.3 0.4 -1.9 1.4 0.8 1.6 1.2 -1.0 -1.1
High cholesterol (Self-reported) 0.2 0.3 1.3 0.6 0.3 0.2 -1.0 -0.1 0.6 0.8 1.1 -1.2 -0.2 0.2 -0.2 -0.1 0.3 -0.3 0.1 0.2 0.1 -0.4 -0.5 0.2 0.5
Medication: Bendroflumethiazide 0.1 0.2 1.0 0.7 0.1 -0.3 -0.6 -0.0 0.5 0.5 1.0 -0.6 -0.2 -0.2 0.1 0.0 0.2 0.1 -0.3 0.4 0.4 -0.1 -0.1 -0.2 0.5
Medication: Paracetamol 0.9 1.4 4.9 -0.9 0.9 0.5 1.5 -1.0 1.4 2.2 1.4 0.1 1.5 1.5 -0.8 1.4 -1.5 0.9 0.8 -0.5 1.2 -0.8 -0.6 1.2 1.3
Medication: Lisinopril 0.5 0.6 1.3 0.3 -0.5 0.9 -1.1 0.8 -0.6 -0.1 -0.6 -1.2 -0.7 -0.9 0.4 -1.1 1.1 -1.1 0.5 1.2 -1.0 0.1 0.2 -0.3 -0.7
Medication: Atorvastatin 2.0 2.5 5.2 2.2 -1.6 -1.1 -2.3 2.0 -1.7 -1.0 -0.8 -0.5 -1.7 -1.7 1.7 -1.9 1.6 -0.4 -1.3 2.2 -0.4 1.8 1.6 -1.3 -1.7
Illnesses of father: High blood pressure 0.7 0.9 2.1 0.5 -1.1 -0.8 -0.8 1.1 -0.9 -0.7 -0.4 -0.5 -1.0 -1.3 1.3 -0.6 -0.2 0.2 -1.1 1.2 -0.2 1.1 1.0 -1.5 -1.0
Alcohol drinker status: Never 0.3 0.3 1.8 -0.7 0.1 -0.2 0.6 -0.4 -0.3 -0.5 -0.7 -0.0 0.1 0.3 -0.4 0.3 -0.6 -1.3 -0.2 -1.0 -1.1 -0.3 -0.6 -0.4 0.1
Ever smoked 0.2 0.4 1.5 -0.9 1.2 -0.9 -0.5 0.1 0.1 -0.0 -0.7 -1.1 -1.0 -0.1 0.1 -0.1 -0.5 -1.0 -0.7 0.1 -0.5 0.0 -0.2 -0.1 0.1
Basal metabolic rate 1.8 9.9 18.9 -3.8 3.7 2.3 4.1 -3.4 3.5 3.6 3.2 1.8 3.9 4.3 -3.2 3.3 -2.1 1.1 3.0 -2.8 1.4 -3.0 -2.6 3.5 3.3
Leg fat percentage (left) 0.1 0.5 1.9 -0.8 1.1 0.0 -1.1 0.4 -0.2 -0.8 -1.3 -1.3 -1.4 -0.6 0.5 -0.8 -0.1 -0.7 -0.3 0.0 -0.2 -0.1 -0.0 -0.7 -0.2
Arm fat-free mass (left) 1.5 7.5 15.0 -3.4 3.3 1.9 3.5 -3.1 3.0 3.2 2.6 1.3 3.1 3.9 -2.9 2.9 -1.8 0.4 2.5 -2.6 0.6 -2.7 -2.6 3.1 2.8
Number of operations (self-reported) 1.5 2.2 4.3 -1.3 1.4 1.4 1.0 -1.8 1.7 1.5 1.3 -0.7 0.0 1.6 -1.9 1.7 -1.6 -0.7 1.7 -1.3 -0.1 -1.9 -1.8 2.0 2.1
Average weekly beer plus cider intake 0.8 1.2 5.9 -0.6 1.4 0.5 1.5 -1.0 0.9 0.4 0.9 0.5 0.5 1.2 -0.4 1.2 -1.8 1.9 0.7 -0.8 2.4 -0.5 -0.2 0.9 0.8
Irritability 0.7 1.1 5.0 -0.5 0.2 -0.6 -1.0 -0.5 -0.1 -0.4 -1.8 -1.8 -1.8 -0.6 -0.1 0.1 -1.3 -2.2 -0.7 -0.8 -1.9 -0.2 -0.8 -1.0 -0.1
Risk taking 0.8 1.2 2.7 0.5 -0.2 0.7 1.6 -1.1 1.1 1.6 1.2 1.1 1.6 1.6 -1.1 1.3 -1.0 0.6 0.9 -0.7 0.4 -1.0 -0.8 1.2 1.0
Ever had prostate specific antigen (PSA) test 0.2 0.2 1.1 1.1 -0.3 -0.7 -0.3 0.5 -0.1 -0.3 0.1 0.1 0.2 -0.4 0.3 -0.3 0.5 0.7 -0.5 0.6 0.4 0.5 0.5 0.3 -0.1
Fractured/broken bones in last 5 years 0.3 0.4 1.4 0.8 -0.5 -1.2 0.1 0.5 -0.4 0.3 0.1 1.0 0.9 -0.4 0.6 -0.3 0.4 0.7 -1.0 0.6 0.5 0.6 0.7 -0.1 -0.5
Age started oral contraceptive pill 0.6 0.8 7.0 -0.9 0.1 0.1 -1.2 -0.5 0.6 0.5 0.3 -2.6 -1.4 0.0 -0.8 -0.2 -0.1 -1.3 0.2 -0.4 -0.9 -0.5 -1.2 0.5 0.4
Diastolic blood pressure, automated reading 2.3 7.1 12.9 3.1 -1.8 -3.1 -3.6 2.9 -2.7 -2.3 -0.5 -1.3 -2.2 -2.6 3.1 -3.4 3.0 1.4 -3.2 3.3 1.6 3.2 2.9 -2.3 -2.6
Ever depressed for a whole week 0.9 1.2 3.8 1.2 -0.7 -1.9 -1.5 0.5 -0.7 -0.9 -1.3 -1.6 -1.9 -1.0 0.7 -0.5 -0.6 -0.7 -1.8 0.3 -0.6 0.8 0.2 -1.0 -0.7
Unable to work because of sickness or disability 0.1 0.2 0.9 0.4 -0.9 0.8 0.6 0.1 0.2 0.3 0.4 0.5 -0.1 0.2 0.2 0.3 -0.2 0.5 0.7 0.3 0.4 -0.0 0.2 -0.2 0.1
Commuting to job workplace: Cycle 0.7 0.9 2.7 -1.1 0.7 0.9 0.8 -0.9 1.0 1.0 -0.0 -0.9 -0.4 0.8 -1.3 0.6 -1.1 -0.8 1.2 -0.9 -0.6 -1.1 -1.1 1.6 0.5
Myopia 0.7 1.0 3.1 0.4 -0.9 -1.2 -0.4 1.0 -1.3 -0.9 -1.0 1.3 0.3 -0.6 1.0 -0.9 1.5 -0.4 -1.5 0.0 -1.1 1.1 0.8 -1.8 -0.9
Vascular/heart problems diagnosed by doctor 0.3 0.9 6.0 -1.3 -0.3 0.5 1.7 -0.9 0.3 -0.2 -1.1 1.1 0.2 0.9 -0.7 1.4 -2.5 0.3 0.6 -1.4 0.2 -0.4 -0.5 0.5 0.3
Cholesterol lowering medication 0.5 0.7 1.7 -0.1 1.0 0.9 0.0 -0.6 1.2 1.2 1.3 -1.1 0.5 0.6 -0.9 0.5 -0.4 0.1 1.1 -0.2 0.4 -0.7 -0.9 1.3 0.8
Medication: Omeprazole (e.g. Zanprol) 1.0 1.2 3.4 1.4 -0.2 -0.8 -0.9 1.3 -1.4 -0.6 -0.6 -0.3 -0.8 -0.7 1.6 -1.3 0.7 0.8 -1.0 1.8 0.7 1.5 1.5 -1.4 -1.2
Pain experienced in last month 3.6 6.1 10.9 2.2 -2.4 -2.0 -2.1 2.8 -3.0 -3.3 -3.2 0.7 -1.6 -2.2 2.7 -3.0 2.7 1.1 -2.3 2.7 0.2 2.9 2.7 -2.7 -3.0
Supplements: Calcium 0.8 0.9 2.8 0.5 -1.0 -0.7 -1.0 0.7 -0.9 -1.0 -1.7 -0.1 -0.6 -1.0 0.6 -0.6 -0.0 -1.5 -0.9 0.1 -1.6 0.7 0.2 -1.5 -0.9
Basal cell carcinoma (self-reported) 1.4 1.7 3.2 -1.0 1.2 0.7 1.6 -1.8 1.6 1.3 1.0 0.5 0.9 1.7 -1.6 1.6 -1.3 -0.5 0.8 -1.8 -0.0 -1.7 -1.8 0.9 1.4
Heart attack/myocardial infarction (self-reported) 1.3 1.6 5.0 1.6 -1.4 -0.2 -1.6 1.4 -1.4 -1.7 -0.6 -0.4 -1.0 -1.6 1.1 -1.8 2.2 -0.8 -0.6 1.0 -1.1 1.1 0.8 -1.4 -1.4
Deep venous thrombosis (DVT) (self-reported) 1.6 2.1 7.4 1.3 -1.6 -0.9 -1.7 0.9 -1.4 -1.4 -2.0 -1.3 -2.0 -1.5 0.5 -1.4 1.0 -2.3 -1.0 0.6 -2.7 1.0 0.2 -1.1 -1.3
Heart disease (siblings) 0.5 0.6 2.9 0.3 -0.2 0.0 -1.3 0.6 -0.4 -1.0 -0.7 -0.7 -0.3 -1.3 0.1 -1.1 1.4 -1.1 -0.1 0.4 -1.7 0.1 0.0 -0.3 -0.5
Alcohol drinker status: Previous 0.6 0.7 3.9 0.9 -0.6 -0.4 -1.5 -0.1 0.1 0.5 0.1 -2.0 -1.9 -0.5 -0.2 0.0 -0.7 -1.2 -0.3 -0.0 -0.9 -0.1 -0.5 0.2 0.2
Pack years of smoking 1.8 2.7 8.5 -0.9 1.4 1.9 1.5 -1.8 2.3 1.9 2.9 -0.3 1.4 2.0 -1.7 1.3 -0.2 0.4 2.1 -1.0 0.7 -1.5 -1.4 2.1 1.9
Impedance of whole body 10.6 53.7 81.9 7.0 -6.4 -7.6 -7.2 8.8 -8.2 -8.5 -7.7 0.0 -5.7 -8.6 9.1 -7.7 4.5 3.2 -8.2 8.4 2.5 8.9 8.7 -8.0 -8.0
Leg fat mass (left) 0.3 1.1 5.2 -2.1 2.3 0.9 0.6 -1.0 1.2 0.6 -0.1 -0.6 0.2 1.1 -0.9 0.7 -1.0 -0.4 0.9 -1.2 -0.1 -1.2 -1.1 0.7 1.1
Arm predicted mass (left) 1.6 8.1 15.7 -3.7 3.4 2.1 3.9 -3.1 3.1 3.2 2.5 1.6 3.4 4.0 -3.0 2.9 -1.9 0.6 2.7 -2.7 0.7 -2.7 -2.5 3.2 2.8