Hub : Genes

RP11-538P18.2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.1450 0.0400 3.0e-11 0.153 NA 0.181 NA 0.182 1.6e-12 NA 1.0e-14 NA 9.4e-15
2 GTEx Adipose Visceral Omentum 0.2300 0.0730 2.9e-08 0.105 NA 0.159 NA 0.147 4.2e-06 NA 1.3e-08 NA 4.8e-08
3 GTEx Artery Aorta 0.1080 0.0440 1.4e-04 0.087 NA 0.082 NA 0.082 1.6e-05 NA 2.9e-05 NA 2.9e-05
4 GTEx Artery Coronary 0.1080 0.0460 9.3e-04 0.160 NA 0.078 NA 0.099 4.6e-06 NA 1.3e-03 NA 3.2e-04
5 GTEx Artery Tibial 0.1712 0.0454 1.1e-13 0.142 NA 0.207 NA 0.206 2.9e-11 NA 3.7e-16 NA 4.7e-16
6 GTEx Brain Cerebellar Hemisphere 0.1730 0.0800 4.2e-03 0.106 NA 0.029 NA 0.037 1.2e-03 NA 6.1e-02 NA 4.1e-02
7 GTEx Brain Cerebellum 0.1870 0.0730 2.9e-04 0.057 NA 0.098 NA 0.083 9.2e-03 NA 8.0e-04 NA 1.9e-03
8 GTEx Breast Mammary Tissue 0.1710 0.0540 2.1e-06 0.136 NA 0.156 NA 0.161 1.8e-07 NA 2.1e-08 NA 1.2e-08
9 GTEx Breast Mammary Tissue (Male) 0.3046 0.1263 8.7e-03 0.113 NA 0.071 NA 0.095 1.4e-03 NA 1.0e-02 NA 3.3e-03
10 GTEx Breast Mammary Tissue (Female) 0.1994 0.0759 3.1e-04 0.139 NA 0.169 NA 0.161 6.3e-05 NA 9.4e-06 NA 1.6e-05
11 GTEx Cells Transformed fibroblasts 0.0960 0.0350 2.4e-06 0.081 NA 0.131 NA 0.080 1.1e-06 NA 5.1e-10 NA 1.3e-06
12 GTEx Colon Sigmoid 0.1120 0.0520 4.8e-03 0.048 NA 0.078 NA 0.082 8.6e-03 NA 1.0e-03 NA 7.6e-04
13 GTEx Colon Transverse 0.0690 0.0340 3.9e-03 0.105 NA 0.078 NA 0.084 1.1e-05 NA 1.4e-04 NA 8.4e-05
14 GTEx Esophagus Gastroesophageal Junction 0.2150 0.0770 3.4e-05 0.115 NA 0.118 NA 0.123 6.2e-05 NA 4.9e-05 NA 3.5e-05
15 GTEx Esophagus Mucosa 0.1230 0.0420 2.1e-06 0.097 NA 0.133 NA 0.137 4.9e-07 NA 3.4e-09 NA 1.9e-09
16 GTEx Esophagus Muscularis 0.1130 0.0400 5.7e-06 0.157 NA 0.135 NA 0.154 8.3e-10 NA 1.5e-08 NA 1.2e-09
17 GTEx Lung 0.1570 0.0420 1.0e-11 0.114 NA 0.169 NA 0.165 5.3e-09 NA 6.6e-13 NA 1.2e-12
18 GTEx Muscle Skeletal 0.0863 0.0317 5.9e-06 0.077 NA 0.044 NA 0.049 4.9e-08 NA 3.6e-05 NA 1.3e-05
19 GTEx Nerve Tibial 0.2063 0.0530 1.2e-13 0.180 NA 0.203 NA 0.189 9.0e-13 NA 2.1e-14 NA 2.0e-13
20 GTEx Ovary 0.2330 0.1100 4.5e-03 0.082 NA 0.056 NA 0.130 4.7e-03 NA 1.7e-02 NA 4.5e-04
21 GTEx Pancreas 0.1420 0.0740 3.6e-03 0.016 NA 0.008 NA 0.019 7.0e-02 NA 1.4e-01 NA 5.3e-02
22 GTEx Pituitary 0.1660 0.0880 9.8e-03 0.033 NA 0.010 NA 0.027 5.2e-02 NA 1.7e-01 NA 6.9e-02
23 GTEx Skin Not Sun Exposed Suprapubic 0.0940 0.0320 3.6e-06 0.098 NA 0.116 NA 0.043 4.8e-06 NA 6.8e-07 NA 2.1e-03
24 GTEx Skin Sun Exposed Lower leg 0.1320 0.0390 9.4e-10 0.116 NA 0.142 NA 0.096 7.8e-10 NA 7.8e-12 NA 2.6e-08
25 GTEx Stomach 0.0630 0.0330 6.0e-03 0.042 NA 0.037 NA 0.044 4.5e-03 NA 7.1e-03 NA 3.4e-03
26 GTEx Thyroid 0.1440 0.0470 2.9e-08 0.127 NA 0.107 NA 0.123 5.8e-10 NA 1.6e-08 NA 1.2e-09
27 GTEx Vagina 0.2460 0.1050 5.7e-03 0.189 NA 0.164 NA 0.179 4.1e-05 NA 1.4e-04 NA 6.7e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bipolar Disorder (2018) 3.6 5.7 9.2 2.7 2.6 2.5 2.4 2.5 1.7 2.4 2.5 2.2 2.8 2.5 1.6 2.0 3.0 2.0 -2.4 2.8 2.3 3.0 2.1 2.3 1.8 2.8 2.3 2.4 2.0 1.7
Bipolar Disorder or Schizophrenia 2.3 5.6 8.8 2.5 2.8 2.6 2.8 2.7 1.9 2.2 2.5 1.5 3.0 2.6 1.6 1.6 2.7 2.4 -2.8 2.9 2.2 2.6 2.1 2.5 1.1 2.8 2.6 2.3 1.9 1.8
Depressed Affect (Nagel 2018) 0.2 0.4 1.3 0.5 -1.2 0.1 -0.7 0.1 -1.0 -0.6 0.5 0.3 1.0 -0.1 -0.6 0.3 0.8 -0.2 0.9 0.7 0.0 0.7 0.3 -0.4 0.9 0.3 0.2 0.3 1.0 -0.9
Depression (Nagel 2018) 2.0 3.0 7.1 2.2 1.0 1.8 0.5 1.6 1.3 0.1 2.2 2.1 2.0 1.7 -0.2 2.3 1.5 1.4 -0.3 1.9 2.1 2.2 1.9 1.1 2.3 1.7 2.0 2.2 2.7 1.1
Intelligence (Savage-Jansen 2018) 0.1 0.4 2.4 -0.7 -0.3 -0.7 -0.1 -0.9 0.1 0.1 -1.0 -0.3 -1.6 -0.5 0.8 -0.6 -0.5 -0.3 0.0 -0.9 -0.5 -0.9 -0.2 -0.7 -0.7 -0.9 -0.5 -0.7 -0.5 -0.3
Neuroticism (Nagel 2018) 0.5 1.2 6.0 -0.4 -2.4 -1.0 -1.4 -1.0 -1.9 -0.7 -0.7 -0.6 -0.0 -1.3 -1.2 -0.9 0.5 -1.2 1.6 -0.1 -1.1 -0.3 -0.4 -1.5 -0.3 -0.6 -0.9 -0.9 0.3 -1.9
Schizophrenia (2018) 0.6 1.3 2.8 1.0 1.5 1.3 1.7 1.5 1.0 0.9 1.1 0.2 1.5 1.4 0.7 0.4 1.0 1.4 -1.6 1.5 0.9 0.9 0.9 1.3 -0.0 1.2 1.4 1.0 0.8 1.0
Schizophrenia vs Biploar Disorder 1.6 2.1 3.6 -1.8 -1.2 -1.4 -1.4 -1.7 -1.0 -1.5 -1.3 -1.7 -1.1 -1.5 -1.1 -1.3 -1.8 -1.8 1.5 -1.4 -1.6 -1.9 -1.5 -1.2 -0.9 -1.8 -1.4 -1.3 -1.6 -1.0
Worry (Nagel 2018) 2.3 4.9 10.7 -1.9 -3.3 -2.6 -2.4 -2.4 -2.8 -1.7 -2.3 -1.5 -1.8 -2.6 -2.1 -2.1 -1.0 -2.4 2.5 -1.8 -2.4 -1.9 -1.6 -2.6 -1.4 -2.1 -2.3 -2.3 -1.2 -2.8
Alzheimer’s Disease (in mother) 0.7 0.8 1.9 -0.9 -0.7 -0.8 -1.0 -1.3 -0.8 -1.3 -0.8 -0.4 -1.0 -0.9 -0.5 -0.5 -1.1 -0.9 1.0 -1.2 -0.7 -1.4 -1.0 -0.8 -0.2 -0.8 -0.9 -0.7 -1.1 -0.5
Alzheimer’s Disease (in father) 1.5 1.7 3.2 -1.1 -1.8 -1.7 -1.3 -1.6 -1.7 -0.7 -1.5 -1.0 -1.2 -1.7 -0.3 -1.3 -0.4 -0.9 1.4 -1.2 -1.4 -1.1 -0.9 -1.5 -1.0 -1.0 -1.5 -1.5 -0.9 -1.8
Alzheimer’s Disease (including proxy) 1.5 2.2 3.8 -1.2 -1.4 -1.9 -1.8 -2.0 -1.6 -1.5 -1.5 -0.6 -1.6 -1.8 -0.8 -1.1 -1.0 -1.5 1.8 -1.8 -1.4 -1.7 -1.4 -1.5 -0.6 -1.2 -1.7 -1.4 -1.3 -1.4
Crohns Disease (2017) 1.0 2.2 5.8 -1.3 -1.5 -1.5 -1.5 -1.7 -1.9 -2.4 -1.1 -1.2 -0.7 -1.6 -1.8 -1.1 -1.4 -1.2 1.5 -1.2 -1.4 -1.6 -1.6 -1.6 -0.8 -1.3 -1.6 -1.2 -1.3 -1.9
Irritable Bowel Disease (IBD) 2.3 5.4 16.6 -1.9 -2.6 -2.5 -3.1 -2.3 -2.8 -4.1 -1.4 -2.1 -0.6 -2.7 -2.1 -1.4 -1.7 -2.4 3.2 -1.9 -2.4 -2.0 -2.4 -2.3 -0.8 -1.8 -2.5 -1.7 -1.8 -2.9
Ulcerative Colitis (UC) 1.6 3.0 9.5 -1.3 -2.1 -1.8 -2.9 -1.5 -2.1 -3.1 -0.7 -1.5 -0.1 -2.1 -1.2 -0.5 -1.5 -1.7 3.1 -1.3 -1.6 -1.1 -1.8 -1.8 0.0 -1.4 -1.9 -0.9 -1.1 -2.2
Major Depression (MDD) 2.0 2.5 4.5 1.9 1.8 1.5 1.5 0.9 1.7 1.6 1.2 1.2 0.6 1.6 0.7 1.3 2.1 1.5 -1.5 1.1 1.7 1.6 2.1 1.7 1.6 1.9 1.8 1.3 2.1 1.8
Reaction Time 0.1 0.2 0.7 0.6 0.4 0.4 0.3 0.5 -0.0 0.8 0.6 0.7 0.3 0.5 -0.7 0.7 0.3 0.5 -0.3 0.7 0.6 0.8 0.2 0.1 -0.0 0.4 0.5 0.6 0.3 0.2
Verbal and Numeric Reasoning (VNR) 0.2 0.5 1.6 -0.6 -0.7 -0.9 0.1 -0.6 -0.7 0.2 -1.0 -0.2 -1.1 -0.5 0.7 -0.9 -0.0 -0.4 -0.1 -0.4 -0.7 -0.6 -0.4 -1.0 -1.2 -0.6 -0.6 -0.9 -0.7 -0.9
Breast Cancer 1.3 3.0 9.3 -1.1 -1.9 -1.4 -2.6 -1.7 -2.7 -2.9 -0.8 -0.6 -0.9 -1.9 -0.5 -0.1 -1.4 -0.9 2.7 -1.2 -1.1 -1.2 -2.4 -2.6 -0.2 -1.7 -1.6 -0.7 -1.3 -3.0
Ovarian Cancer 0.5 0.6 2.8 -0.1 -0.2 -0.6 -0.8 -1.1 -1.5 -0.6 -0.5 -0.2 -0.9 -0.8 0.9 -0.1 0.1 -0.1 0.6 -0.6 -0.3 -0.5 -0.7 -1.5 -0.8 -0.5 -0.7 -0.4 -0.7 -1.7
Prostate Cancer 0.1 0.1 0.5 -0.1 -0.2 0.0 0.2 -0.4 -0.4 -0.6 -0.3 -0.2 -0.5 -0.1 0.7 -0.1 -0.0 0.2 -0.2 -0.2 -0.0 -0.1 -0.2 -0.3 -0.3 -0.4 0.0 -0.1 0.1 -0.4
Age at First Birth 0.5 0.7 1.8 -0.6 0.3 -0.6 -0.4 -0.5 -0.8 -0.8 -0.8 -0.7 -0.7 -0.8 -0.9 -1.1 0.3 -0.8 0.4 -0.9 -1.1 -0.9 -0.9 -0.9 -1.4 -0.4 -0.9 -1.1 -1.1 -0.9
Bipolar Disorder (2011) 1.6 1.6 3.3 1.4 1.7 1.2 1.0 1.1 1.7 0.5 1.1 0.9 0.6 1.4 0.9 1.2 1.5 1.0 -1.0 0.8 1.3 1.1 1.5 1.5 1.2 1.4 1.4 1.2 1.3 1.8
Body Mass Index (BMI) (2010) 5.0 6.8 10.0 -2.4 -1.8 -2.7 -2.6 -3.0 -3.2 -3.1 -2.4 -2.2 -2.2 -2.9 -1.9 -2.1 -2.2 -2.3 2.4 -2.7 -2.5 -3.1 -3.1 -2.8 -2.6 -2.4 -2.9 -2.4 -3.0 -2.9
Coronary Artery Disease (CAD) 0.2 0.3 1.2 -0.1 0.8 0.0 1.1 0.2 0.6 1.1 -0.0 0.1 0.4 0.2 -0.0 -0.8 0.3 0.5 -1.0 0.3 -0.1 0.5 0.0 0.3 -0.5 0.4 0.0 -0.5 0.1 0.3
Crohns Disease (2012) 0.5 0.8 1.8 -1.0 -0.7 -1.0 -0.1 -1.1 -0.5 -0.5 -1.1 -1.1 -0.9 -0.8 -1.2 -1.3 -0.7 -0.5 0.0 -0.9 -1.1 -1.0 -0.8 -0.4 -1.2 -0.8 -0.8 -1.1 -0.8 -0.6
Mean Putamen Volume 5.7 6.6 10.8 3.2 2.4 2.7 1.6 2.9 1.5 1.2 3.0 3.3 2.6 2.6 2.1 3.0 2.9 2.9 -1.6 2.9 2.9 2.9 2.3 1.9 2.5 2.6 2.7 3.0 2.7 1.6
Fasting Glucose 0.2 0.2 1.5 -0.4 -0.2 -0.6 -0.2 0.1 0.4 -0.5 -0.4 -0.0 -0.1 -0.4 -1.2 -0.7 -0.3 -0.3 0.3 -0.4 -0.5 -0.7 -0.1 0.6 -0.2 -0.0 -0.4 -0.5 -0.3 0.4
HbA1C 0.4 0.4 1.5 0.6 0.1 0.5 -0.1 0.3 0.3 0.3 0.5 1.0 0.1 0.4 1.0 0.9 0.3 0.7 0.2 0.3 0.8 0.3 0.8 0.5 1.2 0.2 0.7 0.7 1.2 0.3
HDL Cholesterol 1.0 1.7 4.2 1.1 0.5 1.3 0.7 1.4 2.0 1.6 1.4 1.4 1.1 1.3 1.3 1.6 0.0 1.0 -0.6 1.3 1.5 1.6 1.2 1.4 1.6 0.9 1.3 1.4 1.3 1.4
LDL Cholesterol 0.7 1.1 2.0 -1.1 -1.3 -1.0 -1.1 -1.2 -1.2 -1.4 -1.0 -1.1 -0.8 -1.1 0.6 -0.8 -1.0 -0.8 1.0 -1.0 -0.9 -1.1 -0.7 -1.3 -1.0 -1.2 -1.1 -0.9 -0.8 -1.2
Lupus 0.2 0.3 1.6 0.8 0.6 0.4 0.4 0.0 0.3 -0.3 0.3 0.0 0.4 0.3 0.4 0.2 1.3 0.2 -0.3 0.4 0.4 0.7 0.6 0.4 0.2 0.9 0.5 0.2 1.0 -0.0
Neuroticism (2016) 1.1 1.6 4.0 1.6 0.5 1.4 0.2 0.9 -0.0 0.4 1.7 1.4 1.7 1.1 0.9 1.9 1.1 1.1 -0.2 1.6 1.5 1.6 1.1 0.6 2.0 1.1 1.3 1.8 1.7 0.1
Primary Biliary Cirrhosis 0.5 0.7 2.6 -0.5 -1.1 -0.6 -0.6 -1.5 -1.2 -0.6 -0.8 -1.2 -0.7 -0.8 0.6 -0.6 0.1 -0.9 0.4 -0.7 -0.7 -0.3 -0.7 -1.2 -0.8 -0.5 -0.8 -0.7 -0.8 -1.6
Rheumatoid Arthritis 1.1 1.6 2.9 1.1 1.0 1.6 1.7 0.9 1.7 1.4 1.1 0.9 0.4 1.6 1.0 1.3 0.4 1.1 -1.7 1.1 1.5 1.5 1.3 1.3 0.7 0.7 1.6 1.4 1.1 1.4
Schizophrenia (2014) 0.4 0.8 2.0 0.7 1.3 1.1 1.4 0.7 0.8 0.7 0.9 0.2 1.0 1.1 -0.1 0.5 0.3 1.1 -1.4 1.1 0.9 0.7 0.6 1.0 0.2 0.7 1.2 1.0 0.8 0.8
Triglycerides 0.5 0.8 5.2 -0.3 -1.1 -0.5 -1.2 -1.2 -1.4 -2.3 -0.3 -0.3 -0.7 -0.7 0.1 0.2 -0.7 -0.4 1.1 -0.7 -0.4 -0.9 -0.5 -1.3 0.0 -1.1 -0.7 -0.1 -0.4 -1.1
Type 2 Diabetes (T2D) (2012) 2.9 3.4 6.0 -1.9 -1.2 -2.1 -1.1 -2.1 -1.3 -1.0 -2.1 -2.0 -1.7 -1.9 -2.5 -2.3 -1.2 -1.8 1.1 -1.9 -2.2 -1.9 -1.7 -1.6 -2.0 -1.4 -2.1 -2.3 -2.2 -1.7
Ulcerative Colitis 0.9 1.2 5.4 -0.7 -1.2 -1.2 -1.8 -0.9 -1.2 -2.3 -0.4 -0.8 0.2 -1.4 -1.1 -0.4 -0.5 -0.9 1.9 -0.8 -1.1 -0.4 -1.3 -1.0 -0.2 -0.6 -1.1 -0.6 -0.7 -1.8
Blood Eosinophil Count 0.1 0.9 2.9 -0.2 -1.3 -0.8 -1.7 -1.0 -1.5 -1.7 -0.0 -0.0 0.2 -1.0 -0.8 0.1 -0.6 -0.6 1.7 -0.5 -0.4 -0.6 -1.2 -1.2 0.4 -0.5 -1.0 -0.1 -0.5 -1.7
Blood Platelet Count 0.1 0.7 2.7 0.8 -0.5 1.0 0.1 0.6 -0.4 0.8 1.3 0.6 1.6 0.6 -0.3 1.2 0.1 0.7 -0.1 1.4 1.0 1.6 -0.2 0.4 0.4 0.5 0.8 1.2 0.6 -0.7
Blood Red Count 0.1 1.1 3.0 -1.1 -0.4 -0.8 -0.2 -1.1 -0.3 -0.6 -1.2 -1.0 -1.2 -0.8 -0.4 -1.5 -0.4 -1.7 0.3 -1.4 -1.2 -1.6 -1.1 -0.6 -1.5 -0.7 -1.0 -1.3 -1.4 -0.3
Blood White Count 0.5 3.9 8.5 2.3 1.6 2.2 1.6 2.4 1.1 1.8 2.5 1.6 2.9 2.0 1.6 1.8 2.4 1.2 -1.4 2.6 2.0 2.6 1.5 1.8 1.5 2.4 1.9 2.1 1.8 1.0
Heel T-Score 0.8 6.5 15.6 -2.2 -2.3 -2.9 -1.0 -2.6 -3.1 -1.7 -2.8 -3.2 -1.4 -2.8 -1.3 -3.6 0.2 -2.6 1.1 -1.9 -3.3 -2.2 -3.0 -2.2 -4.0 -1.5 -2.5 -3.2 -2.2 -3.4
BMI 3.5 20.1 32.8 -5.0 -4.7 -4.7 -4.5 -4.5 -4.3 -3.9 -4.2 -3.0 -4.8 -4.8 -1.9 -3.1 -5.7 -3.6 4.2 -5.0 -4.1 -5.3 -5.6 -5.0 -3.2 -5.5 -4.9 -4.0 -5.2 -4.3
Height 3.1 60.6 121.0 7.9 8.0 7.1 9.6 7.7 9.4 9.3 5.2 4.6 5.7 8.2 5.3 2.9 11.0 6.1 -8.7 7.0 5.9 6.9 10.4 9.8 4.2 9.7 8.3 5.0 8.9 9.6
Waist Hip Ratio (WHR) 1.9 8.8 17.2 3.6 1.7 3.0 1.9 2.8 2.0 2.5 3.2 2.6 3.6 2.9 1.7 2.8 3.7 2.5 -1.6 3.6 2.9 3.4 3.5 2.9 3.3 3.6 3.3 3.1 4.2 1.9
Systolic Blood Pressure 5.5 27.4 37.3 -5.7 -6.1 -5.6 -5.0 -5.8 -4.7 -4.2 -5.2 -5.0 -4.7 -5.7 -3.8 -4.5 -6.0 -5.5 4.9 -5.4 -5.3 -4.9 -5.6 -5.8 -3.8 -6.0 -5.7 -5.1 -5.2 -5.6
Smoking Status 1.1 2.5 7.1 1.5 0.0 1.4 0.3 1.0 1.3 2.5 1.8 1.8 1.9 1.3 0.1 2.1 0.7 1.1 -0.1 2.0 1.8 2.7 1.7 1.3 2.1 1.1 1.6 1.9 2.4 0.9
Allergy or Eczema 0.4 1.0 1.9 -1.2 -0.6 -1.0 -0.5 -1.0 -0.7 -1.2 -1.2 -1.0 -1.3 -0.9 -0.7 -1.1 -1.0 -1.0 0.4 -1.1 -1.0 -1.4 -0.9 -0.7 -0.9 -1.1 -1.0 -1.2 -1.0 -0.5
Cardiovascular Disease 4.8 16.0 26.4 -3.7 -4.1 -4.1 -4.2 -4.7 -5.1 -4.7 -3.6 -3.6 -3.2 -4.4 -3.6 -3.0 -3.4 -4.2 4.2 -3.7 -3.9 -3.5 -4.4 -4.5 -3.0 -3.9 -4.0 -3.6 -3.4 -5.0
Hypothyroidism (self reported) 1.4 3.2 5.7 -2.0 -1.2 -1.6 -0.6 -2.3 -0.9 -1.4 -2.1 -2.1 -2.4 -1.6 -1.1 -2.1 -1.7 -1.9 0.5 -2.2 -1.8 -2.1 -2.1 -1.4 -2.2 -1.7 -1.7 -2.1 -2.1 -1.2
Respiratory disease 0.9 2.0 6.6 -1.2 -2.1 -1.1 -2.4 -1.1 -1.8 -1.2 -0.6 -0.1 -0.9 -1.4 -0.9 0.3 -2.6 -0.6 2.3 -1.2 -0.7 -0.9 -1.6 -1.8 0.2 -2.0 -1.3 -0.4 -0.9 -1.6
Type 2 Diabetes (T2D) (2018) 2.6 4.8 8.2 -1.9 -1.8 -2.7 -2.5 -2.3 -2.9 -2.4 -1.9 -1.8 -1.3 -2.6 -2.6 -1.8 -1.3 -1.9 2.4 -1.8 -2.4 -2.0 -2.6 -2.3 -1.7 -1.6 -2.5 -2.0 -2.3 -2.8
Lung FEV1/FVC ratio 1.9 9.4 15.5 -3.0 -3.2 -3.4 -3.9 -3.2 -2.9 -3.9 -2.7 -2.3 -2.8 -3.4 -1.8 -1.9 -2.9 -2.9 3.9 -3.4 -2.9 -3.1 -3.2 -3.5 -1.1 -3.2 -3.5 -2.6 -3.3 -3.1
Lung FVC 21.9 111.6 140.7 10.8 10.2 11.7 10.5 11.4 10.1 10.1 11.1 10.5 10.4 11.9 8.4 9.6 9.3 10.7 -10.7 11.6 11.3 11.6 10.5 10.8 8.6 10.5 11.4 10.9 9.8 10.1
Neuroticism 0.5 1.1 6.7 -0.4 -2.6 -1.0 -1.5 -0.9 -1.9 -0.4 -0.6 -0.4 0.1 -1.1 -1.0 -0.5 0.1 -0.8 1.7 -0.0 -1.0 0.1 -0.5 -1.5 0.1 -0.8 -0.8 -0.6 0.2 -1.9
Chronotype (morning person) 0.5 1.1 3.8 1.2 -0.2 0.8 0.3 0.6 0.8 1.2 0.8 0.8 0.8 0.9 0.9 1.0 1.1 0.0 -0.1 1.1 1.0 1.2 1.9 0.9 1.9 0.9 1.0 0.9 1.9 1.1
Hair Pigment 0.0 0.7 2.2 0.8 0.3 0.8 -0.5 0.1 -0.2 -0.9 1.3 1.2 1.3 0.4 0.2 1.3 0.2 -0.2 0.7 0.7 1.0 0.7 0.3 0.3 1.5 0.5 0.7 1.2 1.3 -0.1
Tanning 0.0 0.2 1.1 -0.1 0.1 0.1 -0.5 0.0 0.1 0.7 0.0 0.8 -0.7 0.0 0.4 0.8 -1.1 0.5 0.3 -0.5 0.4 -0.1 -0.3 -0.5 0.6 -0.7 -0.2 0.4 -0.4 0.1
Hand grip strength (left) 3.3 8.6 16.4 3.2 2.9 2.9 3.5 3.3 2.2 3.4 2.6 2.7 3.0 3.0 2.1 1.8 4.0 2.8 -3.3 3.3 2.6 3.3 2.9 3.2 1.8 3.7 2.9 2.3 2.9 2.2
Number of treatments/medications taken 0.5 0.9 3.6 0.1 -0.9 0.2 -1.8 -0.7 -1.2 -1.7 0.8 0.9 0.5 -0.4 -0.6 1.4 -1.2 -0.8 1.9 0.1 0.5 0.1 -0.6 -0.6 1.5 -0.5 -0.1 0.9 0.4 -0.9
Average weekly spirits intake 0.9 1.2 3.6 -1.2 -0.6 -0.7 -1.5 -1.2 -0.4 -0.8 -1.0 -0.6 -1.6 -1.0 -0.5 -0.2 -1.9 -0.6 1.4 -1.8 -0.7 -1.4 -1.0 -1.2 -0.6 -1.5 -0.9 -0.7 -1.2 -0.4
Sensitivity / hurt feelings 0.2 0.3 1.6 0.3 -1.1 -0.1 -0.7 -0.3 -1.3 -1.2 0.2 -0.0 0.8 -0.4 0.2 -0.2 0.8 -0.4 0.8 0.3 -0.2 -0.0 0.2 -0.4 0.2 0.3 -0.0 0.0 0.6 -0.9
Frequency of depressed mood in last 2 weeks 1.9 2.7 6.8 2.0 0.8 1.5 0.5 1.5 1.2 -0.2 2.0 1.7 2.2 1.4 0.4 1.8 1.5 1.0 -0.2 1.8 1.7 1.8 2.0 1.6 2.5 1.9 1.8 1.9 2.6 1.1
Hearing difficulty/problems: Yes 0.2 0.2 1.7 0.0 -0.6 0.2 -0.4 -0.2 -0.2 1.3 0.2 0.4 0.0 -0.2 -1.2 0.5 -0.5 0.6 0.5 0.1 0.3 0.4 0.0 0.1 0.8 -0.2 0.1 0.3 0.5 -0.2
Relative age of first facial hair 0.1 0.3 2.1 0.0 -0.4 -0.3 -0.6 -0.6 -1.2 -1.4 -0.0 0.1 0.1 -0.5 -0.3 0.1 0.1 -0.3 0.6 -0.1 -0.2 -0.5 -0.6 -0.7 0.1 -0.1 -0.5 -0.1 -0.3 -1.1
Other serious medical condition/disability diagnosed by doctor 0.2 0.2 0.8 -0.6 0.1 -0.2 0.5 -0.1 0.2 0.5 -0.6 -0.4 -0.9 -0.0 -0.0 -0.7 -0.9 -0.2 -0.6 -0.5 -0.2 -0.7 0.1 0.0 -0.8 -0.6 -0.1 -0.5 -0.2 0.3
Ever used hormone-replacement therapy (HRT) 0.2 0.2 0.9 0.5 -0.1 0.2 0.0 0.3 0.6 0.6 0.3 1.0 0.0 0.4 0.3 0.5 0.0 0.7 -0.0 0.3 0.5 0.5 0.8 0.3 0.7 0.2 0.6 0.5 1.0 0.4
Ever had hysterectomy (womb removed) 0.5 0.6 1.7 -0.7 -0.3 -0.9 -0.5 -0.3 -0.6 -0.9 -0.7 -0.5 -0.6 -0.8 -0.7 -0.8 -0.1 -0.3 0.4 -0.6 -0.9 -0.9 -1.0 -0.7 -1.3 -0.5 -1.0 -0.8 -1.1 -0.8
Systolic blood pressure, automated reading 6.7 19.4 27.2 -5.1 -4.4 -4.8 -3.7 -4.9 -3.3 -2.7 -4.7 -4.5 -4.5 -4.7 -3.1 -4.2 -5.1 -5.2 3.6 -5.0 -4.7 -4.4 -4.6 -4.4 -3.2 -5.0 -4.8 -4.5 -4.8 -3.8
Eye problems/disorders: Diabetes related eye disease 2.3 2.5 5.3 -1.5 -1.6 -1.9 -2.1 -1.6 -1.6 -1.8 -1.4 -1.4 -1.2 -1.9 -1.4 -1.1 -1.5 -1.7 2.3 -1.6 -1.7 -1.7 -1.6 -1.4 -0.6 -1.4 -1.6 -1.4 -1.4 -1.5
Angina 1.3 1.7 2.4 -1.4 -1.1 -1.5 -1.5 -0.8 -1.2 -1.2 -1.3 -1.2 -0.9 -1.5 -1.0 -1.2 -1.3 -1.3 1.3 -1.3 -1.5 -1.5 -1.3 -1.3 -1.2 -1.3 -1.5 -1.3 -1.5 -1.3
Medication for hormone replacement therapy 0.4 0.4 1.4 -0.6 -0.7 -0.7 -0.1 -1.0 0.3 -0.1 -1.1 -1.1 -1.0 -0.5 0.0 -1.2 0.0 -0.6 0.2 -0.8 -0.8 -0.8 0.0 -0.2 -0.8 -0.3 -0.4 -1.0 -0.1 0.1
Vitamin and mineral supplements 0.3 0.4 1.5 0.8 0.4 0.5 0.2 0.1 0.2 -0.0 0.6 0.3 0.8 0.5 0.1 0.5 1.2 -0.1 -0.0 0.6 0.4 0.9 0.7 0.7 1.0 1.0 0.6 0.5 0.7 0.5
Supplements: Zinc 0.5 0.5 3.5 0.4 0.6 0.7 1.4 0.2 0.5 1.9 0.2 0.5 0.0 0.8 0.6 0.1 0.3 0.7 -1.4 0.5 0.6 0.5 0.5 0.7 -0.6 0.5 0.6 0.3 0.3 0.6
Medication: Co-codamol 0.3 0.4 2.0 -0.0 -0.4 -0.3 -1.2 -0.5 -0.2 -1.4 -0.0 -0.2 -0.2 -0.4 -1.1 0.3 -0.2 -0.7 1.4 -0.5 -0.2 -0.4 0.3 -0.3 1.0 -0.3 -0.2 0.1 0.3 0.1
Medication: Metformin 3.4 4.8 7.8 -2.1 -1.7 -2.5 -2.8 -1.8 -2.8 -2.8 -1.8 -1.5 -1.2 -2.6 -1.8 -1.6 -2.0 -1.2 2.7 -2.0 -2.3 -2.3 -2.8 -2.4 -1.6 -1.9 -2.5 -1.9 -2.6 -2.6
Diabetes (father) 0.7 0.8 3.7 1.0 1.4 0.5 0.7 0.4 1.1 0.2 0.5 -0.0 0.8 0.6 1.9 0.1 1.8 0.4 -0.5 0.5 0.4 0.4 1.3 1.4 0.1 1.6 0.6 0.4 0.9 1.1
Diabetes (mother) 1.2 1.5 2.6 -1.4 -0.9 -1.5 -1.0 -1.6 -1.1 -0.8 -1.2 -0.8 -1.5 -1.2 -1.5 -1.0 -1.5 -1.5 0.9 -1.4 -1.2 -1.2 -1.4 -1.2 -0.8 -1.5 -1.3 -1.1 -1.4 -1.0
Severe depression (siblings) 0.6 0.6 1.5 1.1 -0.1 0.5 -0.3 0.4 -0.4 -0.9 1.2 1.1 1.1 0.4 0.2 1.2 1.1 0.6 0.4 1.1 0.8 0.7 0.3 0.0 1.2 0.6 0.7 1.1 1.0 -0.5
Pack years adult smoking proportion 2.5 3.8 6.8 2.1 2.1 2.1 1.8 1.8 2.0 2.0 1.8 2.0 1.5 2.0 2.6 1.7 2.0 1.7 -1.7 1.8 2.0 1.8 2.5 2.0 1.5 2.1 2.1 1.9 2.2 1.8
Impedance of leg (right) 0.6 2.9 8.7 1.6 3.0 1.3 2.7 1.2 2.1 0.9 0.9 0.2 0.7 1.9 0.8 0.1 2.6 0.8 -2.7 1.2 1.2 0.6 2.3 2.4 -0.6 2.3 1.7 0.8 1.4 2.3
Leg fat-free mass (left) 0.0 0.1 0.8 -0.2 -0.9 -0.2 0.0 -0.2 -0.1 0.4 -0.2 -0.2 0.1 -0.3 0.1 -0.4 0.1 -0.2 0.2 0.0 -0.4 0.0 -0.4 -0.1 0.3 -0.1 -0.2 -0.3 0.1 -0.4
Trunk fat percentage 0.8 3.2 7.2 -2.2 -1.6 -1.7 -1.4 -1.8 -1.2 -1.0 -1.7 -1.3 -2.1 -1.8 1.0 -1.5 -2.5 -1.4 1.1 -2.1 -1.6 -2.7 -2.4 -1.6 -1.8 -2.2 -1.7 -1.7 -2.4 -1.4
Hand grip strength (right) 3.6 9.8 22.7 3.4 3.2 3.1 4.2 3.5 2.6 3.6 2.6 2.2 3.1 3.3 2.1 1.4 4.8 2.7 -4.0 3.6 2.6 3.3 3.0 3.4 1.6 4.1 3.0 2.2 2.8 2.5
Townsend deprivation index at recruitment 0.3 0.4 2.3 -0.9 -1.5 -0.7 -0.7 -0.3 -0.3 -0.1 -0.6 -0.6 -0.5 -0.6 -0.1 -0.6 -1.0 -0.4 0.6 -0.6 -0.7 -0.5 -0.4 -0.5 -0.2 -0.9 -0.5 -0.6 -0.6 -0.3
Current tobacco smoking 0.8 1.3 5.0 1.1 0.1 1.3 -0.2 0.3 0.7 0.9 1.4 1.5 1.0 0.9 0.2 1.9 0.1 0.2 0.3 1.0 1.5 1.6 1.5 0.7 2.2 0.5 1.2 1.6 1.8 0.9
Average weekly fortified wine intake 0.3 0.3 0.8 -0.3 -0.5 -0.5 -0.5 -0.7 -0.6 -0.6 -0.6 -0.6 -0.9 -0.6 -0.1 -0.4 0.0 -0.8 0.7 -0.8 -0.4 -0.4 -0.3 -0.7 -0.1 -0.4 -0.5 -0.5 0.0 -0.7
Maternal smoking around birth 2.4 3.5 7.1 2.1 0.6 1.7 0.7 1.6 1.5 1.0 2.3 1.8 2.2 1.7 0.4 2.5 1.3 1.8 -0.5 2.0 2.2 2.7 2.0 1.7 2.6 1.8 2.0 2.4 2.6 1.3
Fed-up feelings 0.6 1.2 5.1 1.1 -0.5 0.9 -0.4 0.9 0.4 0.2 1.3 1.1 1.7 0.6 -0.2 1.2 0.8 0.2 0.8 1.3 0.9 1.4 1.4 0.7 2.3 0.9 1.0 1.2 1.9 0.6
Frequency of unenthusiasm / disinterest in last 2 weeks 1.7 2.3 5.9 1.8 0.6 1.4 0.1 1.3 0.7 -0.8 2.1 1.8 2.2 1.2 -0.1 2.0 1.0 1.0 0.0 1.9 1.8 1.8 1.5 1.1 2.4 1.4 1.5 2.0 2.3 0.5
Relative age voice broke 1.1 1.7 4.8 1.6 1.6 1.1 1.2 0.9 1.0 1.3 1.1 0.8 1.4 1.3 0.2 0.6 2.2 1.0 -1.1 1.2 0.9 1.2 1.8 1.7 0.5 2.0 1.2 1.0 1.4 1.5
Taking other prescription medications 0.3 0.4 1.6 0.1 -0.8 0.2 -1.0 -0.7 -1.3 -1.0 0.2 0.6 -0.2 -0.3 0.1 0.7 -0.5 -0.4 1.2 -0.2 0.2 -0.1 -0.3 -0.7 1.2 -0.4 -0.1 0.3 0.3 -0.8
Age when periods started (menarche) 0.1 0.1 0.7 0.1 -0.0 0.4 0.5 0.6 -0.2 0.8 0.2 0.4 0.2 0.4 -0.0 0.1 -0.0 -0.1 -0.5 0.5 0.3 0.1 0.3 0.3 0.6 -0.0 0.4 0.2 0.4 0.3
Bilateral oophorectomy (both ovaries removed) 1.1 1.3 2.0 -1.3 -0.5 -1.2 -1.3 -0.8 -0.7 -1.3 -1.3 -0.9 -1.4 -1.2 0.1 -1.1 -0.9 -1.4 1.3 -1.4 -1.4 -1.4 -0.9 -1.3 -0.7 -1.3 -1.2 -1.3 -1.2 -0.7
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.2 3.5 -0.8 -1.2 -1.4 -0.6 -1.1 -1.9 -1.0 -1.0 -1.4 -0.3 -1.2 -0.7 -1.2 0.2 -1.4 0.7 -0.6 -1.3 -0.8 -1.6 -1.1 -1.2 -0.4 -1.1 -1.2 -0.9 -1.8
Tinnitus: Yes, but not now, but have in the past 1.2 1.3 3.4 -1.0 -1.1 -0.6 -1.2 -1.2 -1.3 -1.8 -0.6 -0.6 -1.0 -1.0 -1.4 -0.2 -1.9 -1.2 1.0 -1.0 -0.6 -1.3 -1.5 -1.3 -0.6 -1.5 -0.8 -0.5 -0.9 -1.3
Qualifications: CSEs or equivalent 2.0 2.6 6.3 -1.3 -1.9 -1.4 -2.4 -1.7 -1.8 -2.5 -1.1 -1.2 -1.1 -1.8 -1.2 -0.6 -1.5 -1.5 2.4 -1.6 -1.4 -1.3 -1.8 -2.0 -0.4 -1.6 -1.5 -1.1 -1.3 -2.0
Serious illness, injury or assault to yourself 0.6 0.7 2.1 0.6 -0.9 0.9 0.3 0.6 1.0 0.9 1.0 0.8 0.9 0.7 0.2 1.2 -0.1 0.6 -0.3 1.0 1.0 1.3 0.4 0.8 1.5 0.3 0.8 1.1 1.0 0.4
High blood pressure 7.8 21.9 33.4 -4.5 -4.6 -5.1 -4.8 -5.8 -5.5 -4.5 -4.5 -4.0 -4.0 -5.3 -4.3 -3.9 -3.9 -5.0 5.0 -4.7 -4.8 -4.3 -5.2 -5.0 -3.5 -4.5 -4.7 -4.5 -4.1 -5.5
Hayfever, allergic rhinitis or eczema 0.4 0.8 1.5 -1.1 -0.6 -1.2 -0.5 -0.6 -0.6 -0.9 -1.1 -1.1 -0.9 -1.0 -0.6 -1.2 -0.5 -0.9 0.5 -0.9 -1.1 -1.0 -0.9 -0.7 -1.2 -0.8 -1.1 -1.2 -1.1 -0.6
Multivitamins +/- minerals 0.3 0.4 1.1 -0.6 -0.4 -0.5 -0.3 -0.4 -0.7 -0.4 -0.6 -0.2 -0.9 -0.6 1.0 -0.3 -0.8 -0.5 0.2 -0.7 -0.2 -1.0 -0.6 -0.7 -0.6 -0.8 -0.5 -0.5 -0.5 -0.7
Stomach or abdominal pain in last month 4.9 6.2 14.3 -2.1 -3.8 -2.5 -3.0 -3.0 -3.5 -2.5 -2.0 -1.6 -1.9 -2.8 -2.5 -1.3 -2.4 -1.9 3.1 -2.0 -2.1 -1.8 -2.6 -3.2 -1.2 -2.7 -2.2 -1.9 -1.6 -3.4
Supplements: Glucosamine 0.1 0.1 0.8 0.3 0.5 0.6 -0.0 -0.0 0.2 -0.1 0.2 0.3 -0.5 0.3 0.6 0.9 -0.2 -0.2 -0.1 -0.3 0.7 0.1 -0.1 -0.3 0.3 -0.2 0.3 0.5 0.1 0.0
Diverticular disease/diverticulitis (self-reported) 0.4 0.5 1.2 -0.6 -1.0 -1.0 -0.6 -0.1 -0.6 -1.1 -0.7 -0.2 -0.9 -0.7 -0.4 -0.4 -0.8 -0.3 0.5 -0.7 -0.6 -0.8 -0.7 -0.9 -0.1 -0.8 -0.8 -0.6 -0.5 -0.8
Medication: Atenolol 0.4 0.5 2.6 -0.6 -0.9 -0.4 -1.0 -1.0 -0.3 -1.0 -0.3 -0.1 -0.5 -0.6 -1.1 0.2 -1.6 -1.1 1.0 -0.6 -0.2 -0.5 -0.2 -0.2 0.9 -0.9 -0.3 -0.1 0.2 -0.2
Medication: Levothyroxine sodium 0.2 0.3 1.2 -0.4 -0.0 -0.1 0.8 -0.4 -0.3 0.3 -0.7 -0.9 -0.7 -0.2 -0.5 -1.1 0.0 -0.3 -0.8 -0.4 -0.5 -0.3 -0.5 -0.1 -1.0 -0.1 -0.4 -0.8 -0.5 -0.3
Sitting height 3.5 24.7 42.3 5.3 5.4 4.9 6.0 5.2 5.6 4.8 4.0 3.8 4.1 5.5 3.0 2.8 6.5 4.6 -5.6 4.9 4.4 4.8 5.8 5.7 3.1 6.0 5.1 4.0 5.2 5.5
Chronic bronchitis/emphysema (father) 0.8 1.0 2.2 0.9 0.7 1.1 0.9 1.1 1.5 0.8 1.1 1.2 0.8 1.2 0.2 1.1 0.2 1.4 -0.9 1.1 1.2 0.6 0.7 1.2 0.7 0.9 1.2 1.1 1.0 1.1
High blood pressure (mother) 4.6 6.4 14.4 -2.4 -2.2 -2.5 -2.5 -3.4 -2.6 -3.0 -2.1 -2.5 -1.7 -2.6 -3.8 -2.1 -2.2 -2.8 2.5 -2.4 -2.5 -2.3 -3.0 -2.6 -1.6 -2.3 -2.5 -2.3 -2.4 -2.7
Body mass index (BMI) 2.2 9.3 18.5 -3.4 -3.2 -3.0 -3.2 -3.0 -3.0 -2.6 -2.6 -1.9 -3.0 -3.3 -0.5 -1.8 -4.2 -2.3 3.0 -3.4 -2.7 -3.5 -4.3 -3.4 -1.8 -3.8 -3.2 -2.5 -3.7 -3.2
Impedance of leg (left) 0.6 2.7 7.5 1.5 2.7 1.2 2.7 1.2 2.1 1.3 0.7 0.2 0.5 1.8 1.0 0.0 2.3 1.0 -2.7 1.1 1.1 0.6 2.3 2.2 -0.6 2.0 1.6 0.7 1.3 2.2
Leg predicted mass (left) 0.0 0.1 0.8 -0.2 -0.9 -0.2 0.0 -0.2 -0.1 0.4 -0.2 -0.2 0.1 -0.3 0.1 -0.5 0.1 -0.2 0.3 0.0 -0.4 0.0 -0.5 -0.1 0.3 -0.1 -0.2 -0.4 0.1 -0.3
Trunk fat mass 0.5 2.2 5.1 -1.8 -1.5 -1.5 -1.0 -1.5 -1.0 -0.7 -1.6 -1.1 -1.7 -1.5 0.9 -1.4 -1.8 -1.2 0.8 -1.8 -1.5 -2.3 -2.1 -1.3 -1.4 -1.7 -1.4 -1.6 -1.9 -1.2
Waist circumference 0.9 3.1 5.8 -1.9 -2.3 -1.8 -2.0 -1.8 -1.9 -1.3 -1.5 -0.8 -1.6 -2.0 0.2 -1.0 -2.4 -1.2 1.9 -1.9 -1.6 -2.2 -2.4 -1.9 -0.9 -2.1 -1.8 -1.4 -1.9 -2.0
Number of incorrect matches in round 1.9 3.1 4.7 -1.8 -2.1 -1.6 -1.7 -2.1 -2.2 -1.7 -1.6 -1.8 -1.5 -2.0 -0.8 -1.4 -1.7 -2.0 1.6 -1.8 -1.7 -1.7 -1.8 -2.0 -1.3 -1.9 -1.8 -1.6 -1.7 -2.1
Past tobacco smoking 0.9 1.6 4.7 -1.1 0.6 -1.0 -0.2 -1.3 -0.3 -2.0 -1.6 -1.7 -2.1 -0.8 -0.5 -1.5 -0.7 -1.1 0.0 -1.9 -1.2 -2.2 -0.6 -0.8 -1.3 -1.0 -1.1 -1.4 -1.6 0.1
Alcohol usually taken with meals 0.6 1.0 4.6 -0.6 0.7 -0.5 0.1 -0.8 -0.7 -1.1 -1.3 -1.3 -2.1 -0.5 0.5 -0.9 -0.3 -0.6 -0.2 -1.7 -0.6 -1.4 -0.8 -1.0 -1.6 -0.8 -0.7 -1.0 -1.3 -0.4
Nervous feelings 0.5 0.9 2.4 -0.7 -1.4 -1.0 -1.2 -0.9 -1.6 -1.0 -0.8 0.2 -0.6 -1.1 -1.0 -0.5 -0.5 -0.6 1.2 -0.5 -0.9 -0.7 -0.6 -1.4 0.1 -1.0 -0.9 -0.7 -0.5 -1.5
Frequency of tenseness / restlessness in last 2 weeks 1.2 1.9 9.0 1.5 -0.4 1.1 -0.9 0.8 -0.5 -1.1 1.9 2.0 1.7 0.7 -0.0 2.4 0.3 0.6 0.9 1.4 1.6 1.5 0.8 0.2 3.0 0.6 1.1 2.0 1.9 -0.4
Hearing difficulty/problems with background noise 1.4 2.2 4.8 1.7 0.8 1.3 0.9 1.3 0.2 1.7 1.8 1.9 2.1 1.1 0.0 1.5 1.7 2.1 -0.8 2.0 1.4 2.2 1.1 1.1 1.4 1.6 1.3 1.6 1.8 0.0
Hair/balding pattern: Pattern 2 1.6 2.0 4.3 1.4 2.1 1.2 2.0 1.4 1.7 1.2 0.9 0.8 0.9 1.6 -0.1 0.3 2.0 1.4 -1.8 1.1 1.0 1.1 1.7 1.9 -0.1 1.9 1.5 0.8 1.5 1.8
Had menopause 0.7 0.8 3.0 0.6 1.1 0.8 1.2 0.7 1.4 1.7 0.5 0.8 0.4 1.0 0.9 0.4 0.6 0.8 -1.3 0.8 0.8 0.7 0.9 1.2 0.0 0.8 0.9 0.5 0.8 1.3
Had other major operations 0.6 0.8 1.6 -1.0 -0.9 -0.9 -1.0 -0.9 -0.6 -0.8 -0.6 -0.6 -0.7 -1.0 -0.3 -0.6 -1.2 -0.7 0.9 -0.9 -0.8 -0.7 -1.3 -1.0 -0.5 -1.1 -1.0 -0.7 -1.2 -1.0
Forced vital capacity (FVC) 19.2 73.8 93.2 8.9 7.8 9.3 8.9 9.0 8.7 8.2 8.6 7.8 8.1 9.7 6.1 7.3 8.4 7.9 -8.5 9.5 8.9 9.3 9.4 9.2 7.1 8.9 9.1 8.5 9.1 8.6
Heel bone mineral density (BMD) T-score, automated (right) 1.0 2.3 5.4 -1.2 -1.9 -1.8 -0.8 -1.6 -2.3 -1.3 -1.5 -2.0 -0.7 -1.7 -1.1 -1.6 -0.2 -2.2 1.0 -1.0 -1.7 -1.1 -2.0 -1.4 -1.3 -0.9 -1.4 -1.6 -1.0 -2.3
Ever unenthusiastic/disinterested for a whole week 0.3 0.3 1.6 -0.2 -1.2 0.3 -0.8 -0.4 -0.4 -0.0 0.4 0.5 0.2 -0.1 0.3 0.9 -1.3 0.4 0.7 0.0 0.3 0.1 -0.3 -0.4 1.1 -0.6 0.1 0.5 0.3 -0.7
Qualifications: None of the above 0.3 0.7 3.0 0.2 -1.0 0.2 -0.5 0.3 0.8 0.7 0.8 0.7 1.0 0.3 0.6 1.0 -0.8 0.4 0.6 0.6 0.7 1.0 0.9 1.1 1.7 0.1 0.6 0.8 1.5 0.7
Financial difficulties in last 2 years 2.6 3.5 5.9 1.7 0.7 2.0 1.8 2.2 2.3 2.2 1.8 1.3 1.9 2.1 0.8 1.4 1.5 1.5 -1.7 2.2 1.8 2.0 2.4 2.2 1.9 1.8 2.1 1.7 2.4 2.1
Mouth/teeth dental problems 0.2 0.3 1.1 -0.3 1.0 0.0 0.0 0.5 0.2 -0.9 -0.4 0.1 -1.0 0.1 0.4 -0.1 -0.6 -0.2 -0.4 -0.7 -0.1 -1.0 0.1 -0.0 -0.5 -0.4 -0.2 -0.2 -1.0 0.8
Heart attack 0.7 0.9 3.8 -0.6 -1.4 -0.9 -1.4 -0.8 -1.8 -1.7 -0.3 -0.4 -0.2 -1.1 0.2 -0.1 -0.8 -0.3 1.4 -0.3 -0.6 -0.4 -1.1 -1.3 -0.1 -0.9 -0.7 -0.4 -0.4 -2.0
Allergy 1.0 2.3 3.6 1.9 1.5 1.7 1.3 1.1 1.5 1.2 1.6 1.3 1.6 1.6 0.1 1.4 1.7 1.1 -1.1 1.6 1.5 1.8 1.6 1.6 1.7 1.9 1.7 1.5 1.9 1.2
Pain all over the body in last month 0.3 0.3 1.2 0.3 0.1 0.7 0.8 0.5 1.0 1.1 0.4 0.2 0.9 0.5 0.2 -0.2 0.4 0.3 -0.8 0.8 0.3 0.6 0.6 0.7 0.5 0.6 0.4 0.2 0.2 0.4
Diabetes (self-reported) 5.8 8.9 18.6 -2.5 -2.6 -3.3 -4.3 -3.0 -3.8 -4.2 -2.2 -2.4 -1.7 -3.5 -2.6 -1.6 -2.3 -2.8 4.3 -2.7 -2.9 -2.7 -3.4 -3.4 -1.3 -2.5 -3.3 -2.3 -3.0 -3.6
Hayfever/allergic rhinitis (self-reported) 1.0 1.4 3.6 -1.0 -0.6 -1.2 -1.3 -1.1 -1.1 -1.9 -1.3 -1.0 -1.0 -1.3 -0.3 -1.2 -0.4 -1.6 1.3 -1.4 -1.4 -1.8 -0.8 -1.0 -0.8 -0.8 -1.2 -1.2 -1.1 -0.7
Medication: Ramipril 0.2 0.3 1.6 -0.0 -0.6 -0.1 -0.5 -0.2 -1.1 -0.7 0.1 -0.1 0.4 -0.4 -0.3 -0.0 0.1 -0.6 0.5 0.1 -0.2 0.2 -0.9 -0.7 -0.4 -0.1 -0.3 -0.0 -0.4 -1.3
Medication: Simvastatin 1.8 2.7 6.2 -1.6 -1.0 -1.7 -1.3 -1.7 -2.5 -1.5 -1.5 -1.4 -1.1 -1.9 -1.1 -1.5 -1.6 -1.6 1.3 -1.4 -1.6 -1.5 -2.2 -1.7 -1.4 -1.4 -1.8 -1.6 -1.9 -2.4
Fluid intelligence score 0.3 0.7 3.0 -0.6 -0.1 -1.0 0.1 -0.7 -0.6 -0.5 -1.1 -0.8 -1.1 -0.6 -0.2 -1.2 0.3 -0.5 -0.1 -0.7 -1.0 -0.9 -0.8 -0.8 -1.7 -0.4 -0.8 -1.1 -1.1 -0.7
Illnesses of siblings 0.8 1.1 4.2 0.4 0.9 0.8 1.9 0.6 1.7 1.8 -0.2 -1.0 -0.1 1.0 0.9 -0.8 1.5 -0.3 -2.0 0.4 0.1 0.4 1.2 1.1 -0.5 0.9 0.7 -0.2 0.3 1.6
Neuroticism score 0.6 1.2 6.0 -0.4 -2.5 -0.8 -1.7 -0.8 -2.0 -1.2 -0.3 -0.1 0.3 -1.2 -1.1 -0.2 -0.2 -1.1 2.0 -0.0 -0.8 -0.3 -0.5 -1.4 0.7 -0.8 -0.6 -0.4 0.3 -1.9
Weight 0.2 0.8 1.8 -1.1 -1.1 -1.0 -0.3 -0.9 -0.6 -0.2 -1.1 -0.7 -1.1 -0.9 0.6 -1.1 -1.0 -0.7 0.4 -1.1 -1.0 -1.3 -1.4 -0.7 -0.7 -1.0 -0.9 -1.1 -1.0 -0.8
Impedance of arm (right) 1.0 4.9 10.8 2.2 2.8 2.0 2.2 2.4 2.9 2.3 1.7 1.2 1.8 2.4 0.7 1.3 2.4 1.9 -2.2 2.0 1.9 1.9 3.3 2.8 0.8 2.5 2.3 1.7 2.4 3.0
Arm fat percentage (right) 1.4 5.4 11.8 -2.7 -2.3 -2.4 -2.7 -2.1 -2.0 -1.7 -2.0 -1.2 -2.4 -2.6 -0.0 -1.2 -3.4 -1.6 2.4 -2.8 -2.0 -2.9 -3.3 -2.5 -1.3 -3.0 -2.5 -1.8 -3.0 -2.2
Trunk fat-free mass 0.1 0.4 3.0 0.6 -0.0 0.3 1.2 0.4 0.6 0.9 0.0 -0.0 0.5 0.4 -0.1 -0.6 1.7 0.1 -0.8 0.6 -0.1 0.6 0.5 0.7 0.5 1.1 0.4 -0.1 0.8 0.3
Hip circumference 1.1 4.9 10.1 -2.8 -2.3 -2.2 -1.6 -2.1 -1.4 -1.1 -2.4 -1.7 -2.6 -2.2 -0.4 -2.1 -3.2 -1.9 1.4 -2.6 -2.2 -2.7 -2.8 -2.1 -2.0 -2.8 -2.3 -2.3 -2.9 -1.6
Time employed in main current job 0.4 0.4 1.1 -0.4 -0.4 -0.6 -0.4 -0.7 -1.1 -1.0 -0.5 -1.0 -0.2 -0.7 0.4 -0.7 0.0 -1.0 0.5 -0.4 -0.7 -0.7 -0.4 -0.4 -1.0 -0.3 -0.5 -0.6 -0.2 -1.0
Alcohol intake versus 10 years previously 0.7 1.1 3.8 0.9 0.4 1.0 -1.0 0.7 -0.1 -1.4 1.7 1.7 1.9 0.5 1.0 1.7 -0.2 1.0 1.0 1.0 1.0 0.4 0.1 0.3 1.9 0.7 0.5 1.5 0.3 0.2
Father’s age at death 0.4 0.6 1.8 -0.4 0.9 -0.1 1.0 -0.1 1.1 0.9 -0.9 -0.7 -1.2 0.3 -0.5 -1.0 0.2 0.1 -1.2 -0.8 -0.4 -0.8 0.3 0.3 -1.3 0.1 -0.1 -0.8 -0.9 1.2
Worrier / anxious feelings 2.7 5.2 8.6 -2.1 -2.9 -2.6 -2.6 -2.2 -2.8 -2.1 -2.3 -1.4 -2.0 -2.7 -1.9 -2.0 -1.5 -2.2 2.6 -2.0 -2.4 -2.4 -2.1 -2.8 -1.4 -2.4 -2.2 -2.3 -1.8 -2.7
Frequency of tiredness / lethargy in last 2 weeks 0.9 1.5 3.8 -1.1 -1.5 -1.1 -1.6 -0.9 -1.9 -1.8 -0.7 -0.3 -0.8 -1.3 -1.4 -0.2 -1.8 -0.7 1.5 -0.9 -0.7 -0.9 -1.4 -1.7 -0.4 -1.6 -1.1 -0.5 -0.9 -2.0
Falls in the last year 0.6 0.8 4.2 -0.5 -1.9 -0.3 -1.3 -0.4 -1.1 -0.8 0.4 0.9 0.2 -0.6 0.7 0.9 -2.1 0.4 1.3 0.1 0.2 0.1 -0.7 -0.9 1.1 -1.2 -0.3 0.4 0.3 -1.4
Hair/balding pattern: Pattern 3 1.6 2.3 5.3 1.2 1.3 1.4 1.8 1.4 1.1 1.9 1.4 2.0 0.8 1.6 2.3 1.4 0.6 1.7 -1.8 1.6 1.8 1.2 1.4 1.6 1.0 1.0 1.7 1.6 1.6 1.4
Number of live births 0.2 0.3 1.0 0.5 0.8 0.2 -0.2 0.7 0.9 -0.1 0.6 0.8 0.6 0.3 0.6 0.7 0.3 1.0 0.1 0.3 0.5 0.6 0.6 0.6 0.8 0.5 0.4 0.6 0.4 0.5
Forced expiratory volume in 1-second (FEV1) 12.1 40.8 52.6 6.6 6.0 6.9 6.6 6.7 6.7 6.0 6.4 5.8 5.9 7.2 4.4 5.5 6.1 5.8 -6.4 6.9 6.7 6.9 7.0 6.8 5.5 6.6 6.8 6.4 6.5 6.6
Pulse rate 1.1 1.8 3.7 -1.4 -0.9 -1.5 -0.6 -1.3 -0.6 -0.1 -1.9 -1.8 -1.9 -1.4 -0.2 -1.8 -0.4 -1.5 0.5 -1.8 -1.6 -1.4 -0.8 -1.1 -1.8 -1.0 -1.4 -1.8 -1.5 -0.8
Happiness 2.7 3.2 5.4 1.7 1.9 2.2 2.2 1.6 1.9 1.5 1.7 2.2 1.1 2.2 0.1 1.7 0.8 2.3 -2.1 1.7 2.2 1.5 1.7 1.8 1.6 1.5 2.1 1.9 1.9 1.8
Noisy workplace 0.2 0.2 0.9 -0.2 -0.8 -0.3 -0.5 -0.9 -0.7 -0.6 0.2 -0.3 0.6 -0.4 -0.3 0.2 -0.5 -0.6 0.6 0.2 -0.2 0.5 -0.6 -0.3 0.4 -0.3 -0.2 0.1 0.1 -0.9
Qualifications: A levels/AS levels or equivalent 0.3 0.6 1.5 -0.5 0.1 -0.8 -0.9 -0.2 -1.1 -1.2 -0.6 0.1 -1.1 -0.7 0.3 0.1 -0.7 -0.0 0.6 -0.8 -0.4 -0.7 -1.0 -1.2 -0.5 -0.8 -0.9 -0.4 -1.1 -1.0
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.4 1.2 0.4 0.1 0.6 0.9 1.1 0.4 0.5 0.6 0.9 0.9 0.5 0.3 0.1 0.5 1.0 -0.9 0.7 0.4 0.6 0.1 0.8 0.0 0.7 0.6 0.4 0.4 0.1
Mouth/teeth dental problems: Dentures 0.8 1.4 4.5 1.1 -0.1 1.1 0.3 0.6 1.2 1.9 1.2 0.8 1.4 0.9 0.8 1.3 0.5 1.1 -0.1 1.1 1.2 1.9 1.4 1.0 2.1 0.9 1.1 1.3 1.9 0.6
Asthma 0.7 1.4 4.9 -1.1 -1.6 -1.0 -1.8 -0.8 -1.9 -0.3 -0.4 0.3 -0.4 -1.2 -0.2 0.2 -2.2 0.1 1.7 -0.4 -0.6 -0.4 -1.5 -1.8 0.0 -1.8 -1.1 -0.3 -0.9 -1.9
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 2.0 0.6 -0.3 0.5 -0.9 0.3 0.5 -1.1 1.0 0.3 0.8 0.3 -0.3 1.4 -0.3 -0.2 0.8 0.4 0.8 0.8 0.2 0.1 1.2 0.2 0.3 1.1 0.4 0.4
Medication: Cholesterol lowering 0.9 1.3 2.8 -1.1 -1.3 -1.2 -1.3 -1.0 -1.6 -1.2 -0.8 -0.9 -0.3 -1.5 0.1 -1.0 -0.7 -1.5 1.5 -0.9 -1.3 -1.1 -1.4 -1.0 -0.2 -0.8 -1.4 -1.0 -1.2 -1.7
Depression (self-reported) 0.1 0.1 0.7 0.0 0.2 -0.3 0.1 0.3 0.1 0.8 -0.2 -0.2 0.2 -0.1 0.8 -0.3 0.3 0.0 -0.1 0.1 -0.2 0.2 0.4 0.4 -0.4 0.4 -0.0 -0.3 0.1 0.2
Medication: Lansoprazole 1.4 1.6 4.0 -1.5 -1.6 -1.1 -1.3 -1.3 -0.6 -0.4 -1.2 -1.6 -1.3 -1.3 -0.9 -1.0 -1.4 -2.0 1.2 -1.4 -1.3 -0.9 -1.2 -1.4 -0.9 -1.5 -1.4 -1.2 -1.5 -0.9
Prospective memory result 0.6 0.7 2.0 0.9 -0.1 0.7 0.7 0.7 0.3 1.0 0.9 0.7 1.3 0.6 -0.0 0.6 0.8 0.4 -0.5 1.1 0.8 1.1 1.0 0.9 1.0 0.9 0.8 0.8 1.4 0.3
Lung cancer (father) 2.2 2.6 4.6 1.6 1.0 1.7 1.2 1.9 1.1 1.8 1.9 1.7 2.1 1.6 0.8 1.8 1.1 2.1 -1.1 2.0 1.7 1.9 1.1 1.7 1.5 1.6 1.7 1.9 1.6 0.9
Illnesses of mother 3.9 4.8 9.4 2.4 2.2 2.3 2.1 3.1 1.9 2.1 2.2 2.3 2.2 2.3 1.9 1.9 2.4 2.6 -2.1 2.6 2.2 2.3 2.2 2.0 1.2 2.4 2.1 2.1 1.9 1.7
Forced expiratory volume in 1-second (FEV1), Best measure 11.3 36.0 46.5 6.3 5.8 6.5 6.3 6.5 6.4 5.8 6.0 5.0 5.7 6.8 3.9 5.0 6.0 5.5 -6.2 6.5 6.1 6.5 6.5 6.4 4.9 6.4 6.2 5.9 5.7 6.2
Pulse wave Arterial Stiffness index 0.2 0.2 0.6 -0.6 -0.8 -0.2 -0.2 -0.3 -0.3 -0.7 -0.4 -0.1 -0.5 -0.3 -0.2 -0.4 -0.7 -0.7 0.2 -0.3 -0.4 -0.4 -0.3 -0.5 0.1 -0.7 -0.4 -0.4 -0.3 -0.4
Impedance of arm (left) 0.8 3.8 9.2 1.9 2.7 1.8 2.1 2.0 2.5 1.9 1.4 1.1 1.4 2.2 0.7 1.0 2.0 1.9 -2.0 1.8 1.7 1.5 3.0 2.4 0.5 2.1 2.1 1.5 2.2 2.7
Arm fat mass (right) 1.1 4.4 8.4 -2.4 -2.2 -2.3 -2.1 -2.0 -1.7 -1.4 -2.0 -1.4 -2.2 -2.3 0.1 -1.5 -2.7 -1.6 2.0 -2.5 -2.0 -2.7 -2.9 -2.1 -1.4 -2.5 -2.2 -1.9 -2.6 -1.9
Trunk predicted mass 0.1 0.6 3.5 0.7 0.1 0.4 1.3 0.5 0.7 1.1 0.1 0.1 0.6 0.5 0.0 -0.5 1.9 0.3 -0.9 0.7 0.1 0.7 0.6 0.9 0.5 1.3 0.5 -0.0 1.0 0.4
Standing height 1.9 19.0 45.3 4.5 4.1 4.0 5.9 4.2 4.8 4.8 2.9 2.1 3.6 4.7 2.1 1.2 6.7 3.3 -5.2 4.5 3.2 4.3 5.7 5.3 2.1 5.7 4.5 2.6 5.3 4.8
Length of working week for main job 2.7 3.0 5.4 -2.1 -1.7 -1.9 -0.8 -1.9 -0.9 -0.9 -2.1 -2.3 -2.0 -1.7 -0.8 -2.1 -1.9 -1.6 0.7 -1.9 -1.9 -2.3 -1.3 -1.3 -1.8 -1.9 -1.8 -2.0 -1.8 -1.2
Exposure to tobacco smoke at home 0.7 0.8 3.3 0.9 -0.5 0.8 -0.4 0.0 0.3 0.1 1.2 0.9 1.1 0.6 0.8 1.5 0.5 0.3 0.5 1.0 1.0 1.1 1.0 0.7 1.8 0.6 0.9 1.2 1.6 0.3
Breastfed as a baby 0.2 0.3 1.2 0.2 1.1 0.2 0.8 0.7 0.7 0.6 -0.1 -0.2 -0.2 0.4 0.6 -0.4 0.8 -0.1 -1.0 -0.1 0.1 -0.3 0.1 0.3 -0.5 0.5 -0.1 -0.1 -0.7 0.7
Tense / ‘highly strung’ 0.5 0.9 3.8 -0.2 -1.8 -0.6 -1.3 -1.4 -2.0 -1.4 -0.1 -0.3 0.4 -0.9 -0.9 -0.1 -0.1 -1.2 1.6 0.1 -0.6 -0.0 -0.4 -0.9 0.4 -0.4 -0.4 -0.2 0.5 -1.6
Seen doctor (GP) for nerves, anxiety, tension or depression 4.3 6.5 11.4 2.6 1.8 2.6 2.2 2.9 2.9 3.2 2.4 1.7 2.8 2.6 1.1 1.8 2.8 1.8 -2.1 2.8 2.2 3.0 3.4 3.0 2.2 2.9 2.6 2.2 3.0 2.8
Hair/balding pattern: Pattern 4 0.4 0.9 3.1 -0.7 -1.8 -0.8 -0.8 -0.8 -1.4 -0.0 -0.7 -1.4 -0.2 -1.0 -0.2 -0.8 -0.3 -0.9 0.6 -0.4 -1.0 -0.0 -0.9 -1.6 -0.5 -0.8 -1.1 -0.8 -1.1 -1.6
Birth weight of first child 0.5 0.8 2.5 0.9 1.0 1.0 0.1 0.8 0.8 -0.0 0.8 1.4 0.1 0.9 1.2 1.4 0.5 0.9 -0.1 0.3 1.0 0.5 1.3 0.7 1.3 0.5 0.9 1.1 0.8 1.6
Peak expiratory flow (PEF) 0.1 0.2 1.3 -0.1 0.5 0.4 0.5 0.0 0.5 0.5 -0.1 0.4 -1.2 0.4 0.0 0.3 -0.6 0.2 -0.7 -0.4 0.5 -0.2 0.1 -0.1 -0.0 -0.5 0.2 0.2 -0.5 0.7
Pulse wave reflection index 0.0 0.1 0.4 -0.1 -0.3 0.3 0.1 0.1 0.1 -0.5 0.1 -0.1 0.1 0.2 -0.6 0.1 -0.6 -0.0 -0.0 0.2 0.2 0.2 0.0 0.2 0.1 -0.1 0.1 0.1 0.3 0.1
Ever highly irritable/argumentative for 2 days 0.9 1.1 3.3 1.1 -0.0 0.7 0.4 0.2 0.1 0.2 1.3 1.5 0.9 0.9 0.5 1.6 0.1 1.6 -0.4 1.3 1.4 1.2 1.1 0.7 1.2 0.5 1.2 1.4 1.8 0.3
Loud music exposure frequency 0.5 0.5 1.6 0.7 -0.6 0.6 0.3 0.7 -0.3 0.5 0.9 1.0 1.1 0.5 0.5 0.9 0.4 1.2 -0.4 1.3 0.8 1.1 -0.0 -0.1 0.7 0.3 0.5 0.9 0.7 -0.5
Qualifications: O levels/GCSEs or equivalent 0.6 1.0 2.7 -0.6 -0.9 -0.7 -1.7 -1.4 -1.2 -1.3 -0.5 -0.1 -1.1 -1.0 -1.1 0.3 -1.2 -0.6 1.7 -1.1 -0.5 -0.9 -1.0 -1.5 0.2 -1.3 -0.8 -0.3 -0.5 -1.2
Mouth/teeth dental problems: Bleeding gums 0.4 0.6 4.2 0.7 0.8 0.2 1.2 0.1 -0.3 0.3 0.3 -0.2 1.1 0.4 0.8 -0.6 2.0 0.4 -1.0 0.8 -0.0 0.5 0.3 0.8 -0.5 1.4 0.4 -0.1 0.5 -0.1
Blood clot in the leg (DVT) 0.4 0.5 3.0 -0.6 0.1 -0.1 0.9 0.2 -0.3 0.4 -0.5 -0.6 -0.2 -0.1 0.9 -1.0 -0.3 -0.1 -1.1 -0.2 -0.4 -0.7 -1.0 -0.3 -1.7 -0.2 -0.5 -0.7 -1.4 -0.5
Medication: Paracetamol 0.7 1.2 7.4 0.6 -0.4 0.8 -1.6 0.2 0.4 -0.7 1.3 1.5 0.6 0.4 -0.5 2.3 -1.0 0.6 1.5 0.3 1.2 1.1 0.4 -0.2 2.7 -0.3 0.6 1.5 1.1 0.4
Headache pain in last month 3.1 5.4 9.2 -2.4 -2.7 -2.4 -2.7 -2.9 -2.0 -3.0 -2.2 -2.3 -1.9 -2.5 -1.9 -2.0 -2.5 -2.5 2.7 -2.3 -2.4 -2.5 -1.7 -2.4 -1.2 -2.5 -2.1 -2.1 -1.6 -2.2
Medication for cholesterol, blood pressure or diabetes 6.1 10.0 14.8 3.2 3.6 3.3 3.3 3.7 3.6 2.9 3.0 2.8 2.8 3.7 1.6 2.5 3.1 3.4 -3.4 3.2 3.2 3.1 3.5 3.5 1.8 3.3 3.4 2.9 3.0 3.9
Glaucoma (self-reported) 1.7 2.0 3.4 -1.7 -0.9 -1.5 -1.5 -1.2 -0.6 -1.2 -1.5 -1.5 -1.6 -1.5 -0.9 -1.1 -1.7 -1.2 1.4 -1.8 -1.5 -1.3 -1.7 -1.4 -1.3 -1.5 -1.6 -1.5 -1.8 -1.0
Gout (self-reported) 0.5 0.6 3.7 -0.7 -1.1 -0.7 -0.4 -0.8 -0.7 0.3 -0.8 -1.0 -0.2 -0.8 -1.5 -1.0 0.1 -1.9 0.6 -0.5 -1.0 -0.2 -0.5 -0.4 -0.2 -0.4 -0.6 -0.9 -0.1 -0.8
Hypothyroidism/myxoedema (self-reported) 0.0 0.1 0.4 -0.0 -0.1 0.1 0.6 -0.5 0.0 -0.0 -0.1 -0.6 -0.1 0.1 -0.1 -0.4 0.1 -0.4 -0.6 -0.1 -0.0 0.1 -0.4 0.1 -0.5 0.2 -0.1 -0.2 -0.1 -0.2
Medication: Amlodipine 0.4 0.5 2.4 -0.3 -0.9 -0.4 -0.7 -1.2 -1.5 -0.6 -0.2 -0.1 -0.1 -0.8 -0.8 -0.2 -0.3 -0.7 0.7 -0.2 -0.4 -0.2 -1.1 -1.0 -0.6 -0.5 -0.6 -0.3 -0.4 -1.6
Medication: Ventolin 100micrograms inhaler 0.3 0.4 1.6 0.1 0.2 -0.1 -1.1 -0.1 -1.2 -1.2 0.3 1.0 0.1 -0.3 1.0 0.7 -0.4 0.4 0.9 -0.1 0.1 -0.6 -0.5 -0.6 0.1 -0.4 -0.3 0.4 -0.3 -0.7
Birth weight 0.1 0.3 2.1 -0.7 0.2 -0.5 -0.1 0.0 -0.0 0.2 -0.5 -0.8 -0.2 -0.5 0.5 -0.8 -0.1 -0.8 -0.1 -0.3 -0.7 -0.8 -0.6 -0.0 -1.4 -0.3 -0.5 -0.7 -0.9 -0.0
Chronic bronchitis/emphysema (mother) 0.6 0.7 2.5 0.9 -0.1 0.8 0.4 0.5 0.2 0.7 0.9 1.0 0.8 0.8 0.1 1.1 0.4 1.6 -0.3 0.9 0.9 1.0 0.8 0.6 1.0 0.7 0.9 1.0 1.1 0.3
High blood pressure (siblings) 1.7 2.5 5.8 -1.5 -1.4 -1.5 -2.2 -1.4 -2.0 -1.9 -1.0 -0.0 -1.3 -1.7 -0.8 -0.4 -2.4 -0.8 2.1 -1.7 -1.1 -1.7 -2.3 -2.0 -0.7 -1.9 -1.7 -0.9 -1.8 -1.8
Forced vital capacity (FVC), Best measure 16.4 59.9 76.9 8.0 7.3 8.4 8.4 8.3 8.1 7.9 7.6 6.5 7.3 8.8 5.2 6.1 7.8 7.1 -8.2 8.5 7.8 8.4 8.4 8.3 6.0 8.3 8.1 7.4 7.6 7.8
Body fat percentage 1.2 4.6 9.2 -2.5 -1.9 -2.1 -1.8 -2.2 -1.6 -1.4 -2.0 -1.5 -2.5 -2.2 0.7 -1.6 -3.0 -1.7 1.5 -2.6 -1.9 -3.0 -2.9 -2.1 -1.9 -2.6 -2.1 -2.0 -2.8 -1.8
Leg fat percentage (right) 1.4 5.0 10.7 -2.4 -1.6 -2.3 -1.9 -2.5 -2.0 -2.2 -2.0 -1.4 -2.5 -2.3 0.6 -1.6 -2.6 -1.9 1.6 -2.6 -2.0 -3.3 -3.2 -2.2 -2.1 -2.5 -2.3 -1.9 -3.0 -2.2
Arm fat-free mass (right) 0.0 0.2 0.9 -0.1 -0.6 -0.2 0.7 -0.3 -0.1 0.3 -0.5 -0.4 -0.2 -0.1 0.6 -1.0 0.7 -0.3 -0.4 -0.0 -0.5 -0.3 -0.3 0.1 -0.1 0.3 -0.1 -0.6 0.1 -0.3
Exposure to tobacco smoke outside home 0.3 0.4 1.0 0.2 -1.0 0.4 -0.5 0.4 -0.6 -0.5 0.8 0.7 0.9 0.1 0.7 1.0 -0.6 0.3 0.4 0.8 0.5 0.7 -0.6 -0.3 0.6 -0.2 0.4 0.8 0.2 -0.7
Comparative body size at age 10 3.1 8.7 14.4 -3.5 -2.5 -3.1 -2.3 -3.1 -2.8 -2.0 -2.9 -2.6 -2.6 -3.0 -2.1 -2.7 -3.6 -2.8 2.1 -3.0 -3.0 -3.4 -3.8 -2.8 -3.5 -3.4 -2.9 -2.9 -3.3 -2.6
Number of full brothers 1.3 1.6 5.8 -1.4 -1.4 -1.4 -1.9 -1.2 -1.2 -1.1 -0.8 -0.2 -1.0 -1.2 -2.1 -0.2 -2.4 -0.5 1.9 -1.2 -0.9 -1.1 -1.2 -1.2 -0.1 -1.8 -1.0 -0.6 -0.7 -0.9
Worry too long after embarrassment 0.2 0.3 1.3 -0.3 -1.1 -0.2 -0.4 -0.2 -0.6 -0.5 -0.2 -0.7 0.2 -0.5 -0.4 -0.5 0.0 -0.8 0.5 -0.0 -0.5 0.1 -0.2 -0.8 -0.6 -0.4 -0.3 -0.3 -0.2 -1.0
Seen a psychiatrist for nerves, anxiety, tension or depression 1.7 2.1 3.9 1.5 0.9 1.5 1.3 1.9 1.0 2.0 1.4 1.3 1.8 1.5 0.2 1.0 1.3 1.9 -1.2 1.8 1.3 1.8 1.8 1.4 1.4 1.5 1.5 1.4 1.7 1.0
Wheeze or whistling in the chest in last year 1.1 2.0 8.2 -0.7 -1.9 -1.0 -2.9 -1.4 -2.2 -2.0 0.1 0.7 -0.1 -1.4 -0.5 1.0 -1.9 -0.9 2.8 -0.6 -0.3 -0.6 -1.2 -1.6 0.8 -1.5 -1.1 0.2 -0.5 -1.8
Number of children fathered 1.9 2.2 4.5 -1.1 -0.8 -1.3 -1.1 -2.1 -1.4 -1.4 -1.6 -1.4 -2.1 -1.5 -1.4 -1.1 -0.8 -1.3 1.0 -1.9 -1.3 -1.3 -1.8 -1.9 -1.6 -1.4 -1.3 -1.4 -1.5 -1.8
Reason for reducing amount of alcohol drunk: Health precaution 1.2 1.4 3.6 1.1 1.0 1.2 1.1 1.6 0.9 1.9 1.1 1.2 1.3 1.1 0.9 1.0 1.2 0.3 -1.1 1.3 1.1 1.4 1.6 1.2 1.3 1.2 1.0 1.1 1.2 1.0
Age at first live birth 1.4 2.5 4.7 -1.7 -1.3 -1.2 -1.1 -1.7 -1.2 -1.7 -1.6 -2.1 -1.7 -1.4 -0.2 -1.7 -1.1 -2.2 0.9 -1.9 -1.6 -2.1 -1.4 -1.7 -1.7 -1.7 -1.6 -1.7 -1.8 -0.9
Pulse wave peak to peak time 0.4 0.5 1.4 0.9 1.1 0.4 0.5 0.5 0.4 0.8 0.6 0.3 0.7 0.6 0.4 0.5 1.2 1.0 -0.5 0.6 0.6 0.6 0.6 0.8 -0.0 1.1 0.7 0.6 0.6 0.6
Health satisfaction 0.5 0.7 3.1 1.0 0.3 1.0 0.4 -0.1 -0.2 -0.4 1.0 1.1 0.7 0.7 0.7 1.2 0.6 0.7 -0.2 0.8 1.0 0.7 0.4 0.3 1.8 0.7 0.8 1.1 1.0 -0.2
Shortness of breath walking on level ground 0.2 0.2 1.5 -0.1 -0.7 0.0 -0.6 -0.0 0.1 -0.7 0.3 0.2 -0.1 -0.1 1.2 0.7 -0.6 0.1 0.5 -0.1 0.4 0.2 -0.5 -0.6 0.4 -0.6 -0.0 0.4 -0.1 -0.4
Qualifications: College or University degree 0.5 1.4 7.4 -0.7 0.9 -0.7 1.4 0.1 0.2 0.6 -1.8 -1.4 -1.9 -0.3 -0.8 -2.1 1.0 -0.1 -1.5 -1.1 -1.1 -1.3 -0.5 -0.4 -2.7 -0.2 -0.7 -1.7 -1.3 0.2
Eye problems/disorders: None of the above 0.5 0.6 2.0 0.9 0.8 0.7 0.7 1.1 0.7 0.1 0.7 0.5 1.0 0.8 -0.0 0.3 1.4 0.3 -0.6 0.8 0.5 0.5 0.9 0.8 0.6 1.1 0.7 0.6 0.7 0.8
Mouth/teeth dental problems: Loose teeth 0.6 0.8 5.1 -0.2 0.1 0.4 1.8 0.6 1.2 2.3 -0.1 0.1 0.4 0.7 -0.2 -1.0 0.2 0.1 -1.7 0.7 -0.1 0.0 0.6 1.3 -0.8 0.6 0.6 -0.4 0.4 1.3
Emphysema/chronic bronchitis 0.1 0.1 0.3 0.3 -0.3 -0.1 -0.4 0.1 -0.1 -0.5 0.2 0.5 0.2 -0.0 0.1 0.4 0.2 0.4 0.4 0.0 0.2 0.0 0.2 0.2 0.3 0.2 0.1 0.3 0.5 0.1
Medication for pain relief, constipation, heartburn 2.6 4.5 13.7 -2.2 -1.0 -2.3 0.4 -1.6 -1.5 0.3 -3.0 -2.9 -2.4 -1.9 -0.8 -3.7 -0.3 -1.5 -0.4 -2.1 -2.8 -2.3 -1.8 -1.5 -3.7 -1.3 -2.2 -3.2 -2.4 -1.6
Neck or shoulder pain in last month 0.9 1.2 3.2 1.3 0.4 1.2 0.0 0.8 0.4 0.2 1.5 1.3 0.9 1.0 1.7 1.8 0.8 0.8 -0.1 1.1 1.5 1.3 1.4 0.5 1.6 0.7 1.1 1.6 1.3 0.6
Medication: Blood pressure 4.3 7.7 13.3 -2.8 -3.5 -2.9 -3.0 -3.6 -2.9 -2.6 -2.5 -2.3 -2.4 -3.1 -2.4 -1.9 -3.3 -3.2 3.2 -2.6 -2.5 -2.5 -2.8 -2.9 -1.3 -3.0 -2.7 -2.3 -2.0 -3.1
Angina (self-reported) 1.1 1.4 2.0 -1.3 -1.0 -1.3 -1.3 -0.7 -1.2 -1.1 -1.2 -1.1 -0.9 -1.4 -0.7 -1.1 -1.2 -1.2 1.1 -1.2 -1.4 -1.4 -1.2 -1.2 -1.1 -1.2 -1.4 -1.2 -1.4 -1.2
Migraine (self-reported) 0.4 0.5 1.6 -0.6 -0.4 -0.4 -0.2 -0.9 -0.3 -0.5 -0.8 -0.5 -1.3 -0.4 -1.1 -0.7 -0.8 -0.9 0.1 -0.9 -0.5 -1.0 -0.4 -0.7 -0.3 -0.8 -0.5 -0.7 -0.6 -0.2
Medication: Ibuprofen 0.3 0.3 2.1 0.4 -0.4 0.2 -1.0 -0.1 -0.0 -1.4 0.8 -0.1 0.8 -0.0 -0.3 1.0 -0.2 -0.8 0.9 0.2 0.5 0.5 0.1 -0.0 1.0 0.1 0.0 0.8 0.2 -0.1
Medication: Allopurinol 2.4 3.2 5.3 -1.9 -2.2 -1.9 -1.5 -2.0 -1.9 -0.4 -2.1 -2.0 -1.7 -2.0 -2.0 -1.9 -1.2 -2.3 1.7 -1.7 -2.1 -1.4 -1.7 -1.7 -1.4 -1.7 -1.7 -2.1 -1.1 -1.9
Medication: Omeprazole 2.9 3.5 6.2 2.2 1.7 2.0 1.1 1.3 2.5 1.1 2.1 2.0 1.8 2.0 1.7 2.1 1.6 1.4 -1.0 1.7 2.1 2.1 2.1 1.9 2.0 2.0 2.0 2.1 2.1 1.8
Medication: Seretide 50 evohaler 0.8 0.9 3.1 1.0 0.6 0.8 0.4 0.6 -0.8 -0.5 1.3 1.8 1.5 0.7 0.2 1.2 0.5 1.2 -0.4 1.4 1.2 1.2 0.2 0.3 0.7 0.8 0.8 1.2 0.9 -0.6
Mean time to correctly identify matches 0.4 0.8 1.6 0.9 1.0 1.0 1.1 1.1 0.5 1.3 1.0 1.2 0.9 1.1 0.1 0.9 0.5 1.1 -1.1 1.2 1.1 0.9 0.6 0.7 0.3 0.8 0.9 1.0 0.6 0.7
Heart disease (mother) 0.3 0.3 2.0 -0.6 -0.8 -0.1 -0.2 -0.5 0.1 -0.1 -0.5 -0.6 -0.7 -0.4 1.4 -0.5 -0.6 -0.6 0.2 -0.6 -0.5 -0.8 -0.0 -0.3 -0.2 -0.7 -0.3 -0.5 -0.6 -0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 10.4 12.4 17.1 -3.8 -3.3 -3.9 -3.1 -3.6 -3.3 -2.3 -3.8 -3.3 -3.2 -4.0 -2.6 -3.5 -2.8 -3.2 3.0 -3.5 -4.0 -3.9 -4.1 -3.8 -3.3 -3.5 -3.9 -3.9 -3.8 -3.7
Whole body fat mass 0.9 3.8 7.4 -2.3 -1.9 -2.0 -1.5 -2.0 -1.6 -1.1 -2.0 -1.5 -2.1 -2.1 0.5 -1.8 -2.3 -1.6 1.4 -2.3 -2.0 -2.7 -2.7 -1.9 -1.7 -2.2 -2.0 -2.0 -2.4 -1.8
Leg fat mass (right) 1.0 4.0 8.3 -2.2 -1.9 -2.1 -1.6 -2.1 -1.7 -1.5 -1.9 -1.4 -2.1 -2.1 0.3 -1.6 -2.3 -1.7 1.5 -2.3 -1.9 -2.7 -2.9 -1.9 -1.6 -2.2 -2.0 -1.9 -2.5 -1.9
Arm predicted mass (right) 0.0 0.1 0.8 0.0 -0.3 -0.0 0.8 -0.1 0.1 0.7 -0.3 -0.3 -0.1 0.0 0.5 -0.8 0.9 -0.1 -0.6 0.1 -0.3 -0.1 -0.2 0.3 -0.0 0.4 0.0 -0.5 0.2 -0.1
Pulse rate, automated reading 2.2 7.0 11.8 -2.8 -1.3 -2.7 -1.5 -2.7 -1.9 -1.6 -3.3 -3.1 -3.1 -2.7 -1.8 -3.4 -1.3 -2.9 1.4 -3.3 -3.1 -3.2 -2.6 -2.4 -3.4 -2.0 -2.8 -3.4 -3.3 -2.0
Alcohol intake frequency. 1.0 2.3 10.4 -1.3 -0.8 -1.5 -1.8 -1.3 -1.6 -3.2 -0.8 -1.3 -0.2 -1.6 -1.7 -1.1 -1.2 -1.3 1.8 -1.3 -1.5 -1.7 -2.0 -1.1 -0.8 -0.9 -1.6 -1.2 -2.0 -1.4
Comparative height size at age 10 0.5 2.8 8.0 1.4 1.0 1.4 2.8 1.4 2.0 1.9 0.6 -0.0 1.1 1.7 1.2 -0.3 2.7 0.8 -2.4 1.8 0.8 1.5 2.4 2.2 -0.0 2.0 1.9 0.5 2.2 1.8
Number of full sisters 0.3 0.4 1.3 1.0 0.9 0.5 0.4 0.4 0.2 -0.2 0.6 0.9 0.2 0.6 -0.7 0.7 0.8 1.1 -0.6 0.4 0.9 0.4 0.7 0.3 0.4 0.7 0.7 0.7 0.9 0.4
Suffer from ‘nerves’ 0.1 0.2 1.0 0.1 -0.8 -0.3 -0.8 -0.3 -0.7 -0.5 -0.2 -0.0 -0.3 -0.5 -0.8 0.1 0.1 -0.4 1.0 -0.2 -0.2 -0.2 0.4 -0.3 0.2 -0.2 0.1 -0.1 0.8 -0.4
Overall health rating 0.4 0.8 3.5 -0.7 -1.9 -0.7 -1.7 -0.6 -1.1 -0.8 -0.2 -0.3 0.2 -1.1 -0.4 -0.1 -1.0 -1.1 1.8 -0.4 -0.6 -0.5 -0.7 -0.8 0.8 -0.7 -0.9 -0.3 -0.4 -1.2
Chest pain or discomfort 2.9 4.2 7.8 -1.8 -2.2 -2.2 -2.2 -2.1 -2.6 -2.7 -1.6 -1.8 -1.1 -2.2 -2.3 -1.6 -1.6 -2.2 2.1 -1.6 -2.1 -1.5 -2.4 -2.4 -1.7 -1.9 -2.1 -1.7 -1.8 -2.8
Had major operations 0.3 0.4 2.1 0.2 -0.3 0.1 0.5 0.1 -0.8 -0.2 0.4 0.1 1.2 -0.0 1.5 -0.2 0.6 0.4 -0.6 1.0 0.0 0.5 -0.4 -0.0 -0.7 0.5 0.1 0.1 0.1 -1.3
Age at last live birth 0.2 0.3 1.3 -0.4 -0.4 -0.1 -0.6 -0.6 -0.5 -1.1 -0.1 -0.3 -0.3 -0.3 1.0 0.0 -0.5 -1.1 0.4 -0.6 -0.1 -0.7 -0.3 -0.5 0.1 -0.6 -0.4 -0.1 -0.5 -0.1
Family relationship satisfaction 0.8 1.0 3.1 1.1 1.3 0.9 0.9 0.7 0.4 0.3 1.0 1.8 0.6 1.0 0.1 1.1 0.9 1.7 -0.7 0.9 1.1 0.8 0.8 1.0 0.9 1.0 1.1 1.1 1.2 0.8
Leg pain on walking 1.5 1.8 5.4 1.6 0.7 1.4 0.6 1.3 1.0 0.8 1.6 1.0 1.5 1.2 2.3 1.5 1.6 1.6 -0.7 1.6 1.4 1.6 1.3 1.1 1.4 1.4 1.3 1.5 1.3 0.8
Qualifications: NVQ or HND or HNC or equivalent 0.2 0.2 1.1 0.4 -0.2 -0.0 -0.5 -0.2 -0.6 -0.2 0.5 0.5 0.5 -0.0 -1.0 0.8 -0.1 0.3 0.6 0.4 0.3 0.6 -0.2 -0.3 0.9 0.1 0.1 0.6 0.3 -0.6
Commuting to job workplace: Car/motor vehicle 0.7 0.8 3.0 1.2 0.7 0.7 0.1 0.2 0.5 -0.2 1.1 1.0 0.7 0.7 0.6 1.3 0.6 0.8 -0.1 0.7 1.1 1.1 0.8 0.7 1.7 0.8 0.8 1.2 1.2 0.3
Illness, injury, bereavement, stress in last 2 years 0.3 0.4 2.0 -0.5 0.4 -0.7 -0.3 -0.9 -0.4 -0.2 -0.6 -0.8 -0.5 -0.5 0.4 -0.8 0.0 -1.3 0.2 -0.6 -0.6 -0.8 -0.3 -0.4 -1.4 -0.2 -0.6 -0.7 -0.7 -0.1
Medication: Aspirin 0.5 0.6 2.5 0.2 -0.7 -0.0 -1.6 0.3 -1.2 -1.2 0.9 1.1 1.2 -0.4 0.4 1.0 -0.6 -0.0 1.6 0.5 0.3 0.1 -0.0 -0.3 1.3 -0.1 -0.1 0.8 0.1 -0.7
Supplements: Vitamin C 0.3 0.3 1.8 -0.6 -0.4 -0.2 -0.3 -0.3 -0.3 -0.3 -0.4 0.2 -0.7 -0.3 -1.3 0.1 -1.3 0.5 0.1 -0.4 -0.1 -0.4 -0.9 -0.6 -0.7 -0.9 -0.2 -0.2 -0.5 -0.5
Knee pain experienced in last month 0.2 0.3 1.4 0.3 0.0 0.4 -0.6 0.3 0.1 -1.2 0.8 0.9 0.2 0.3 0.7 1.2 -0.6 0.6 0.5 0.2 0.7 0.1 -0.2 -0.1 0.8 -0.2 0.4 0.9 0.2 0.1
Hypertension (Self-reported) 8.3 23.2 35.2 -4.7 -5.0 -5.2 -5.0 -5.9 -5.6 -4.6 -4.5 -4.0 -4.2 -5.4 -4.5 -3.8 -4.6 -5.0 5.2 -4.8 -4.8 -4.4 -5.4 -5.2 -3.4 -4.8 -4.8 -4.5 -4.1 -5.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.8 1.0 1.5 1.0 0.9 1.2 1.0 0.8 1.2 0.8 1.1 1.0 1.0 1.2 0.2 1.0 0.8 0.2 -0.9 1.1 1.1 1.1 1.0 1.1 0.7 1.0 1.2 1.1 1.1 1.0
Illnesses of father: Heart disease 0.2 0.3 1.2 0.2 0.4 0.6 0.4 1.1 0.3 0.5 0.7 0.9 0.5 0.4 -0.0 0.8 -0.6 0.9 -0.5 0.6 0.7 0.7 -0.4 0.0 0.3 0.0 0.4 0.7 -0.3 -0.3
Illnesses of siblings: Diabetes 0.2 0.2 1.1 -0.1 -0.1 -0.5 -0.7 -0.7 -0.9 -1.0 -0.3 0.3 -0.3 -0.4 -0.3 -0.0 -0.3 -0.4 0.7 -0.5 -0.2 -0.6 0.1 -0.3 -0.5 -0.2 -0.3 -0.2 0.2 -0.5
Smoking status: Previous 0.8 1.2 3.7 1.1 -0.2 0.8 0.5 1.1 -0.0 1.3 1.3 1.2 1.9 0.7 0.4 1.1 1.0 1.3 -0.3 1.8 1.0 1.8 0.3 0.9 0.8 1.2 1.0 1.1 1.5 -0.2
Forced expiratory volume in 1-second (FEV1), predicted 0.9 1.9 5.3 1.5 1.3 1.0 1.6 0.9 1.9 1.3 0.7 0.4 0.5 1.4 1.2 0.4 2.3 1.5 -1.4 1.0 1.0 1.1 2.3 1.7 0.9 1.7 1.4 0.7 1.9 1.8
Whole body fat-free mass 0.0 0.1 1.1 0.2 -0.5 0.0 0.6 0.0 0.2 0.7 -0.2 -0.2 0.3 0.0 0.1 -0.6 1.0 -0.1 -0.3 0.3 -0.3 0.4 0.0 0.3 0.3 0.6 0.1 -0.3 0.5 -0.1
Leg fat-free mass (right) 0.0 0.1 1.1 -0.2 -1.0 -0.2 0.1 -0.1 -0.1 0.7 -0.3 -0.2 0.1 -0.3 0.1 -0.5 0.1 -0.1 0.2 0.1 -0.4 0.2 -0.3 -0.2 0.3 -0.1 -0.2 -0.4 0.2 -0.3
Arm fat percentage (left) 1.5 6.1 13.5 -2.8 -2.4 -2.5 -2.7 -2.3 -2.2 -1.9 -2.1 -1.3 -2.6 -2.7 0.0 -1.4 -3.7 -1.5 2.5 -2.9 -2.1 -3.2 -3.4 -2.7 -1.5 -3.2 -2.5 -2.0 -3.1 -2.4
Average weekly red wine intake 0.2 0.3 1.3 0.3 0.7 0.4 0.9 0.3 0.3 1.1 -0.0 -0.0 -0.2 0.5 1.1 -0.1 0.7 -0.1 -0.7 -0.0 0.3 0.3 0.7 0.6 0.2 0.4 0.5 0.1 0.7 0.7
Handedness (chirality/laterality): Left-handed 0.2 0.3 1.3 0.3 -0.4 0.2 0.1 0.2 0.7 0.7 0.2 -0.2 0.6 0.2 1.1 0.2 0.4 -0.3 -0.0 0.5 0.1 1.1 0.8 0.5 0.4 0.4 0.4 0.2 0.8 0.3
Mood swings 0.3 0.6 2.0 0.3 -1.3 -0.4 -1.2 -0.2 -1.3 -1.4 0.2 -0.2 1.0 -0.6 -0.9 -0.0 0.9 -0.6 1.4 0.5 -0.4 0.3 0.1 -0.4 0.8 0.3 -0.0 -0.0 0.8 -1.0
Loneliness, isolation 1.9 2.6 6.6 1.7 0.4 2.0 0.8 2.3 0.7 0.4 2.1 1.7 2.6 1.5 2.1 1.6 1.2 1.8 -0.6 2.0 1.6 1.5 1.7 1.1 2.0 1.5 1.6 1.9 1.6 0.8
Long-standing illness, disability or infirmity 0.3 0.4 1.4 0.5 -0.1 0.6 -0.2 0.9 -0.2 0.7 1.0 1.0 1.2 0.4 0.8 0.9 0.0 0.4 0.2 1.0 0.6 0.8 0.1 0.4 1.2 0.4 0.5 0.9 0.4 0.1
Ever had bowel cancer screening 0.5 0.6 2.8 -0.2 -1.7 -0.3 -1.4 -0.7 -0.9 -0.4 -0.1 0.8 -0.4 -0.6 0.2 0.6 -0.9 -0.2 1.5 -0.3 0.0 -0.1 -0.3 -1.1 1.3 -0.8 -0.3 0.0 0.3 -0.9
Diabetes diagnosed by doctor 2.5 4.2 10.3 -1.4 -1.7 -2.4 -3.2 -1.8 -3.1 -3.1 -1.1 -1.1 -0.6 -2.5 -1.9 -0.9 -1.0 -1.6 3.2 -1.5 -1.9 -1.6 -2.6 -2.3 -0.7 -1.3 -2.3 -1.4 -2.0 -2.9
Ever had stillbirth, spontaneous miscarriage or termination 0.3 0.3 1.5 0.3 0.3 0.2 1.1 0.3 0.4 0.6 -0.2 -0.5 -0.1 0.3 -0.6 -0.5 1.0 -0.2 -1.2 0.2 0.1 0.5 0.3 0.5 -0.8 0.6 0.3 -0.2 0.4 0.2
Friendships satisfaction 2.3 2.9 4.4 2.0 1.6 1.7 1.8 1.3 1.1 1.4 1.7 1.7 1.6 1.9 0.4 1.6 1.8 1.5 -1.7 1.9 1.8 1.8 1.9 1.8 1.5 1.9 1.8 1.8 2.1 1.6
Qualifications: nursing, teaching 1.8 2.7 6.5 -1.9 -0.6 -1.5 -0.4 -1.4 -1.4 -0.9 -2.1 -1.5 -2.2 -1.5 -0.9 -2.1 -1.0 -1.6 0.2 -1.8 -1.8 -2.0 -1.9 -1.7 -2.2 -1.7 -1.7 -2.0 -2.5 -1.3
Commuting to job workplace: Walk 2.2 2.3 4.0 -1.7 -1.5 -1.7 -0.9 -1.2 -1.4 -0.4 -1.7 -1.8 -1.2 -1.7 -0.4 -1.9 -1.1 -1.1 0.8 -1.4 -1.8 -1.3 -1.8 -1.7 -2.0 -1.4 -1.7 -1.9 -1.9 -2.0
Eye problems/disorders: Cataract 0.6 0.7 2.1 0.9 0.4 0.9 0.5 0.5 0.2 0.8 1.1 1.4 0.7 0.8 0.8 1.3 0.2 1.3 -0.4 1.1 1.2 1.0 0.4 0.4 0.8 0.5 0.8 1.2 0.9 0.2
Mouth/teeth dental problems: Mouth ulcers 2.1 3.4 6.8 -1.9 -2.5 -2.3 -1.9 -1.8 -1.5 -0.7 -1.7 -1.7 -1.0 -2.1 -2.6 -1.7 -1.4 -1.6 2.1 -1.2 -2.1 -1.0 -2.3 -2.0 -1.6 -1.6 -2.0 -1.9 -1.4 -2.3
Medication for cholesterol 2.4 3.7 7.2 1.9 1.8 1.9 1.6 2.7 2.5 1.7 1.9 1.6 1.9 2.0 2.0 1.7 1.7 2.0 -1.6 1.9 1.8 1.9 2.4 2.0 1.8 1.9 1.8 1.9 1.5 2.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.5 0.6 2.0 0.7 0.3 1.1 1.2 0.6 0.3 0.8 0.8 0.2 1.1 1.0 -0.8 0.3 0.6 0.7 -1.2 1.4 0.7 0.8 0.5 0.7 0.6 0.6 0.9 0.7 0.8 0.3
Back pain experienced in last month 1.3 1.9 3.5 1.5 1.1 1.4 1.0 1.5 1.7 0.6 1.5 1.1 1.2 1.4 0.5 1.6 1.3 1.5 -0.8 1.3 1.5 1.9 1.5 1.3 1.1 1.3 1.6 1.6 1.8 1.3
Mineral and other dietary supplements 1.8 2.5 4.0 -1.5 -1.8 -2.0 -1.4 -1.7 -1.5 -1.7 -1.6 -1.8 -1.1 -1.7 -2.0 -1.9 -0.8 -1.4 1.5 -1.4 -2.0 -1.5 -1.2 -1.5 -1.3 -1.2 -1.7 -1.8 -1.4 -1.3
Breast cancer (self-reported) 0.3 0.3 2.3 0.4 -0.2 0.2 -0.2 0.5 0.6 0.6 0.4 0.9 -0.1 0.4 -0.4 0.9 -0.4 1.0 0.3 0.0 0.6 0.4 0.7 0.2 1.5 -0.0 0.4 0.7 0.6 0.7
Asthma (self-reported) 1.0 2.0 6.2 -1.4 -1.8 -1.2 -2.1 -1.1 -2.1 -0.9 -0.7 -0.1 -0.8 -1.5 -0.5 0.1 -2.5 -0.1 2.0 -0.9 -0.8 -0.9 -1.8 -2.1 -0.1 -2.1 -1.3 -0.5 -1.1 -2.0
Osteoporosis (self-reported) 1.2 1.5 3.9 1.0 1.3 1.5 1.9 1.4 0.5 1.6 1.1 1.2 1.3 1.4 0.9 0.6 1.0 1.1 -2.0 1.6 1.1 1.5 0.8 1.2 0.5 1.2 1.2 1.0 0.9 0.8
Osteoarthritis (self-reported) 0.2 0.3 1.3 0.4 1.0 0.3 -0.1 1.0 0.7 0.5 0.4 1.1 0.0 0.4 0.8 0.6 -0.0 0.9 -0.2 0.0 0.4 0.2 0.5 0.2 0.4 0.2 0.1 0.6 -0.5 0.7
Medication: Aspirin 0.5 0.6 2.5 0.3 -0.4 -0.1 -1.6 0.4 -1.1 -1.1 0.9 1.3 1.1 -0.4 0.6 1.1 -0.4 -0.1 1.6 0.4 0.3 0.1 0.1 -0.2 1.4 0.0 -0.2 0.8 0.1 -0.6
Medication: Gliclazide 0.3 0.3 1.4 0.1 0.4 -0.8 -0.2 -0.5 -1.1 -0.4 -0.4 -0.5 0.1 -0.6 -0.3 -0.6 0.9 0.5 0.2 0.0 -0.6 0.1 -0.4 -0.3 -1.0 0.5 -0.5 -0.5 -0.4 -1.2
Illnesses of father: None of the above (group 1) 0.1 0.2 0.9 0.4 0.2 0.2 0.3 -0.2 0.1 1.0 -0.1 -0.3 -0.2 0.3 0.2 -0.1 0.9 0.0 -0.3 -0.0 0.1 0.5 0.8 0.2 0.5 0.4 0.2 -0.1 0.6 0.5
Smoking status: Current 0.7 1.1 5.1 0.9 -0.2 1.1 -0.4 0.3 0.8 1.0 1.2 1.4 0.8 0.8 0.0 1.8 -0.2 0.1 0.5 0.9 1.3 1.5 1.3 0.6 2.2 0.3 1.0 1.4 1.6 0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage 9.3 19.6 25.3 4.6 4.6 4.9 4.3 4.8 4.9 4.2 4.5 3.9 3.8 5.0 2.5 4.1 4.2 4.0 -4.2 4.4 4.7 4.8 4.9 4.8 3.9 4.6 4.6 4.5 4.2 4.9
Whole body water mass 0.0 0.2 1.2 0.2 -0.5 0.0 0.7 0.1 0.3 0.8 -0.2 -0.2 0.3 0.1 0.1 -0.6 1.1 -0.0 -0.4 0.3 -0.3 0.4 0.0 0.3 0.3 0.6 0.1 -0.3 0.5 -0.0
Leg predicted mass (right) 0.0 0.1 1.2 -0.3 -1.1 -0.2 0.0 -0.2 -0.1 0.7 -0.3 -0.2 0.1 -0.3 0.1 -0.5 0.0 -0.1 0.2 0.1 -0.5 0.2 -0.3 -0.2 0.3 -0.2 -0.2 -0.4 0.1 -0.4
Arm fat mass (left) 0.9 3.6 7.6 -2.2 -1.9 -1.9 -1.8 -1.8 -1.6 -1.2 -1.8 -1.1 -2.1 -2.1 0.1 -1.3 -2.6 -1.3 1.7 -2.2 -1.8 -2.5 -2.8 -2.0 -1.2 -2.4 -2.0 -1.7 -2.3 -1.8
Number of self-reported non-cancer illnesses 1.1 1.9 6.2 -0.5 -1.7 -0.9 -2.5 -1.5 -2.3 -2.5 -0.4 -0.0 -0.5 -1.4 1.1 0.2 -0.6 -1.7 2.5 -1.0 -0.7 -1.0 -1.1 -1.8 0.7 -1.1 -1.1 -0.3 -0.6 -2.0
Average weekly champagne plus white wine intake 1.9 2.6 5.9 -1.7 -1.6 -1.7 -0.8 -1.4 -1.4 -1.0 -2.0 -1.4 -2.4 -1.4 0.0 -1.6 -1.5 -0.7 0.5 -1.6 -1.5 -1.8 -1.6 -2.1 -2.4 -2.0 -1.5 -1.8 -1.8 -1.5
Miserableness 0.2 0.3 1.4 0.2 -1.2 -0.1 -1.0 -0.1 -0.9 -0.5 0.3 0.2 0.6 -0.4 -0.5 0.4 0.1 0.3 1.1 0.4 -0.0 0.5 -0.2 -0.6 1.1 -0.2 -0.0 0.2 0.6 -0.9
Guilty feelings 0.3 0.4 3.1 0.6 -0.4 0.2 0.4 0.3 -0.1 0.8 0.1 -0.1 0.7 0.2 -0.1 -0.4 1.8 -0.5 -0.2 0.7 -0.1 0.6 1.2 0.5 0.4 0.8 0.5 -0.0 1.2 0.1
Wears glasses or contact lenses 0.7 0.8 2.7 0.8 0.7 0.5 0.5 0.5 1.6 1.2 0.5 0.3 0.4 0.8 1.3 0.5 1.1 0.1 -0.5 0.4 0.7 0.6 1.5 1.3 1.1 1.0 0.8 0.6 0.9 1.7
Ever taken oral contraceptive pill 1.6 1.8 4.9 1.4 1.1 1.1 1.2 0.9 1.9 1.2 1.0 0.6 1.2 1.3 1.7 0.6 1.9 0.8 -1.0 1.2 0.9 1.6 2.2 1.6 1.2 1.5 1.3 1.0 1.8 1.7
Hearing aid user 0.6 0.7 2.5 -1.0 -1.2 -0.7 0.3 -0.7 0.1 0.6 -1.0 -1.6 -0.5 -0.5 -1.2 -1.6 -0.7 -1.0 -0.4 -0.5 -1.0 -0.8 -0.2 -0.2 -1.2 -0.4 -0.7 -1.2 -0.9 0.1
Mother’s age at death 0.3 0.4 2.4 -0.2 0.1 -0.5 0.6 -0.4 -0.2 0.8 -0.8 -0.6 -0.5 -0.4 -1.0 -1.1 0.7 0.0 -0.7 -0.3 -0.7 -0.2 -0.6 -0.3 -1.6 0.3 -0.5 -0.9 -0.8 -0.7
Financial situation satisfaction 0.9 1.1 2.9 1.0 0.5 1.1 1.7 0.8 0.7 0.7 1.1 0.8 1.6 1.2 0.2 0.5 0.9 1.3 -1.6 1.7 0.9 1.1 0.8 1.2 0.4 1.2 1.2 1.0 0.9 0.4
Tinnitus: Yes, now most or all of the time 3.8 4.5 7.3 -2.3 -1.8 -2.3 -2.2 -2.2 -1.5 -0.9 -2.4 -2.3 -2.4 -2.3 -1.4 -2.1 -2.3 -1.9 2.1 -2.7 -2.3 -2.4 -2.0 -2.0 -1.9 -2.2 -2.3 -2.4 -2.2 -1.4
Commuting to job workplace: Public transport 0.7 0.9 2.1 -1.2 -1.2 -0.8 -0.1 -0.5 -0.5 -0.4 -1.1 -0.9 -1.3 -0.7 -0.7 -1.1 -1.3 -0.5 -0.0 -1.0 -0.9 -1.5 -0.8 -0.8 -1.2 -1.2 -0.9 -1.1 -1.2 -0.4
Eye problems/disorders: Glaucoma 2.8 3.3 6.2 -2.2 -1.6 -1.8 -1.6 -1.8 -1.1 -1.2 -1.8 -2.0 -1.9 -1.9 -1.5 -1.5 -2.5 -1.4 1.4 -2.0 -1.8 -1.5 -2.2 -1.9 -1.8 -2.1 -1.9 -1.9 -2.2 -1.6
Medication: Blood pressure 3.0 5.8 10.1 -2.1 -1.9 -2.5 -2.5 -3.0 -3.2 -2.9 -2.0 -1.8 -1.8 -2.7 -2.4 -1.9 -1.8 -2.5 2.5 -2.3 -2.3 -2.4 -3.1 -2.6 -2.3 -2.1 -2.3 -2.1 -2.1 -3.0
Pain type(s) experienced in last month: Hip pain 3.4 4.3 10.9 2.5 1.0 2.3 0.5 2.0 1.9 0.6 2.6 2.2 2.1 2.0 1.8 2.8 1.9 1.4 -0.3 1.8 2.4 2.1 2.5 1.7 3.3 1.9 2.1 2.7 2.5 2.0
Supplements: Fish oil (including cod liver oil) 0.6 0.8 1.8 0.8 1.1 1.4 0.9 1.2 1.1 0.6 0.9 0.7 0.5 1.1 1.4 1.1 0.1 0.5 -1.0 0.7 1.2 0.5 0.7 0.8 0.8 0.5 1.1 1.1 0.7 0.9
High cholesterol (Self-reported) 0.3 0.5 2.4 -0.4 -0.6 -0.5 -0.6 -0.5 -1.4 -1.4 -0.1 -0.7 0.4 -0.8 0.0 -0.5 -0.4 -0.6 0.7 -0.1 -0.6 -0.6 -0.9 -0.6 -0.5 -0.3 -0.7 -0.3 -0.7 -1.5
Medication: Bendroflumethiazide 5.3 8.0 12.3 -2.7 -2.6 -3.4 -2.7 -3.5 -3.2 -2.5 -2.8 -2.6 -2.6 -3.2 -3.2 -2.5 -2.3 -2.9 2.9 -2.9 -2.9 -3.3 -2.9 -2.7 -2.3 -2.6 -2.9 -2.8 -2.2 -3.0
Medication: Paracetamol 0.5 0.8 5.5 0.4 -0.5 0.4 -1.5 -0.5 0.0 -1.1 0.8 0.9 -0.0 0.1 -0.5 1.9 -1.1 -0.1 1.5 -0.1 1.0 0.6 0.3 -0.5 2.3 -0.6 0.3 1.2 1.0 0.1
Medication: Lisinopril 2.1 2.7 4.6 -1.8 -1.7 -2.1 -1.8 -1.8 -1.2 -1.3 -1.8 -1.2 -1.7 -1.9 -0.8 -1.5 -1.7 -1.4 1.9 -1.9 -1.8 -1.5 -1.7 -1.6 -1.1 -1.6 -1.7 -1.8 -1.5 -1.4
Medication: Atorvastatin 0.1 0.1 0.4 -0.2 -0.6 -0.1 0.0 -0.3 -0.0 0.0 -0.0 -0.5 0.4 -0.1 -0.4 -0.5 0.0 -0.1 0.1 0.2 -0.2 -0.2 0.3 0.1 -0.4 -0.1 0.1 -0.2 0.4 0.1
Illnesses of father: High blood pressure 1.4 1.8 3.1 -1.5 -1.2 -1.3 -1.1 -1.4 -1.1 -1.6 -1.2 -1.2 -0.9 -1.4 -1.4 -1.2 -1.6 -1.8 1.2 -1.3 -1.4 -1.2 -1.7 -1.3 -0.7 -1.5 -1.3 -1.3 -1.5 -1.4
Alcohol drinker status: Never 2.9 3.5 6.1 -1.9 -1.4 -2.1 -1.2 -1.9 -1.5 -1.9 -2.0 -2.3 -1.4 -2.0 -2.4 -2.2 -1.1 -2.5 1.4 -1.9 -2.2 -1.8 -1.9 -1.7 -2.2 -1.5 -1.9 -2.1 -1.6 -2.0
Ever smoked 1.2 2.0 5.5 1.4 -0.4 1.4 0.1 1.4 0.4 2.1 1.8 2.1 1.8 1.0 1.2 2.1 0.6 1.2 0.1 2.0 1.6 2.4 0.7 0.5 1.9 0.7 1.4 1.8 1.9 -0.0
Basal metabolic rate 0.0 0.1 0.6 -0.1 -0.6 -0.2 0.5 -0.2 0.0 0.5 -0.4 -0.4 -0.1 -0.2 0.2 -0.8 0.6 -0.3 -0.2 -0.0 -0.5 -0.1 -0.3 0.0 -0.0 0.2 -0.2 -0.6 0.1 -0.2
Leg fat percentage (left) 1.6 5.7 11.4 -2.6 -1.9 -2.4 -2.1 -2.6 -2.2 -2.2 -2.1 -1.5 -2.6 -2.5 0.7 -1.6 -3.0 -1.8 1.8 -2.8 -2.1 -3.3 -3.4 -2.5 -2.0 -2.8 -2.4 -2.0 -3.1 -2.4
Arm fat-free mass (left) 0.0 0.1 0.5 -0.0 -0.6 -0.2 0.6 -0.2 0.0 0.5 -0.4 -0.2 -0.2 -0.1 0.3 -0.7 0.6 -0.1 -0.3 0.0 -0.4 -0.1 -0.3 0.1 0.1 0.3 -0.1 -0.5 0.1 -0.2
Number of operations (self-reported) 0.1 0.2 0.7 0.2 -0.1 0.1 -0.2 0.2 -0.3 -0.2 0.6 0.9 0.6 0.1 0.6 0.6 -0.0 0.5 0.3 0.4 0.3 0.5 -0.3 -0.1 0.4 0.1 0.0 0.5 0.2 -0.5
Average weekly beer plus cider intake 1.3 1.9 4.4 1.4 0.4 1.1 0.8 1.7 1.8 1.8 1.4 0.6 2.0 1.1 -0.1 0.8 1.9 0.9 -0.6 1.6 0.9 2.1 1.6 1.8 1.4 1.9 1.2 1.1 1.6 1.4
Irritability 0.4 0.7 2.8 -0.3 -1.5 -0.5 -1.5 -1.0 -1.6 -0.9 0.0 0.2 0.4 -0.8 -1.1 0.2 -0.4 -1.0 1.7 0.1 -0.4 -0.3 -0.7 -1.0 0.4 -0.6 -0.3 -0.0 0.2 -1.4
Risk taking 3.1 4.5 7.3 2.0 1.8 2.5 2.3 2.5 1.4 2.1 2.3 2.3 2.3 2.4 1.6 1.9 1.3 2.7 -2.3 2.6 2.4 2.4 1.6 2.0 1.3 1.9 2.3 2.2 2.1 1.6
Ever had prostate specific antigen (PSA) test 0.5 0.5 1.7 -0.4 0.3 -0.6 -0.4 -1.0 -0.4 -1.1 -0.8 -0.5 -0.7 -0.8 -0.6 -1.0 0.4 -1.3 0.5 -0.8 -0.8 -1.3 -0.5 -0.4 -0.6 -0.0 -0.7 -0.9 -0.6 -0.6
Fractured/broken bones in last 5 years 0.3 0.4 1.8 -0.7 -1.4 -0.8 -0.6 -0.4 -0.4 0.1 -0.6 0.3 -1.0 -0.5 0.3 -0.0 -1.3 -0.3 0.4 -0.6 -0.3 -0.4 -0.4 -0.6 -0.1 -1.1 -0.6 -0.2 -0.5 -0.2
Age started oral contraceptive pill 0.9 1.1 3.3 -1.2 -0.8 -0.9 -0.9 -1.4 -1.0 -0.6 -1.2 -0.1 -1.5 -1.0 -0.5 -0.7 -1.8 -0.9 0.7 -1.4 -0.9 -1.2 -1.0 -1.1 -0.7 -1.5 -1.0 -0.9 -1.0 -0.7
Diastolic blood pressure, automated reading 9.3 28.9 40.6 -6.0 -4.8 -6.0 -4.2 -5.6 -4.2 -3.7 -5.8 -6.0 -5.2 -5.7 -3.5 -5.6 -5.0 -5.8 4.1 -6.0 -6.0 -5.7 -5.9 -5.2 -5.2 -5.4 -5.9 -5.9 -6.4 -4.8
Ever depressed for a whole week 0.1 0.1 0.7 -0.4 -0.4 -0.0 -0.2 -0.5 -0.1 0.4 -0.3 -0.0 -0.3 -0.2 -0.2 -0.1 -0.9 0.0 0.2 -0.4 -0.1 -0.1 -0.1 -0.2 -0.1 -0.4 -0.1 -0.2 0.0 -0.4
Unable to work because of sickness or disability 1.4 1.8 3.9 1.0 1.5 1.3 1.9 1.6 1.8 1.9 0.9 1.1 0.7 1.5 -0.7 0.6 0.4 1.7 -2.0 1.4 1.3 1.1 1.6 1.6 0.4 1.1 1.5 1.0 1.1 1.5
Commuting to job workplace: Cycle 0.1 0.1 0.5 -0.4 -0.1 -0.3 0.3 -0.4 0.1 -0.5 -0.5 -0.4 -0.6 -0.1 -0.1 -0.6 -0.2 -0.7 -0.3 -0.3 -0.3 -0.7 -0.1 0.3 -0.6 -0.2 -0.1 -0.4 -0.1 0.3
Myopia 1.8 2.6 5.9 -1.2 -1.9 -1.4 -2.3 -1.8 -2.2 -2.3 -1.0 -1.2 -0.9 -1.7 -2.0 -0.5 -1.2 -1.8 2.4 -1.3 -1.4 -1.3 -1.9 -2.0 -0.4 -1.4 -1.4 -1.0 -1.2 -2.2
Vascular/heart problems diagnosed by doctor 6.9 18.8 27.4 4.2 4.4 4.8 4.7 5.2 5.1 4.3 4.1 4.0 3.5 5.0 3.5 3.6 3.6 4.7 -4.8 4.3 4.5 4.1 4.7 4.5 3.2 4.1 4.4 4.2 3.8 5.0
Cholesterol lowering medication 0.1 0.2 1.1 -0.3 0.3 0.2 0.0 -0.2 -1.0 -0.3 0.2 0.5 0.3 -0.0 -1.1 0.0 -1.1 0.1 -0.0 0.2 0.1 -0.2 -0.6 -0.0 -0.6 -0.3 0.1 0.2 -0.2 -0.4
Medication: Omeprazole (e.g. Zanprol) 3.0 3.6 5.4 2.2 1.8 2.1 1.2 1.4 2.3 1.3 2.1 2.0 1.6 2.0 1.7 2.2 1.8 1.7 -1.1 1.8 2.2 2.3 2.0 1.7 1.9 1.9 2.0 2.2 2.2 1.6
Pain experienced in last month 0.2 0.3 1.4 0.1 0.6 -0.1 0.9 0.3 -0.1 1.2 -0.2 -0.4 0.5 0.1 -0.6 -0.8 0.9 -0.2 -0.9 0.2 -0.4 0.2 -0.3 0.6 -0.6 0.8 -0.1 -0.4 -0.3 -0.1
Supplements: Calcium 0.9 1.0 2.7 1.1 0.6 0.9 0.6 0.4 0.1 0.9 1.3 1.6 1.6 0.8 0.8 1.1 0.8 1.0 -0.4 1.5 1.0 1.0 0.5 0.9 0.8 1.1 0.9 1.1 1.2 0.0
Basal cell carcinoma (self-reported) 0.9 1.1 2.2 1.0 0.8 0.8 0.7 1.1 1.3 1.3 0.9 0.8 0.7 1.0 0.6 0.9 1.3 0.7 -0.4 0.8 0.9 1.5 1.1 1.2 1.4 1.0 0.9 0.9 1.3 1.5
Heart attack/myocardial infarction (self-reported) 0.6 0.8 4.0 -0.5 -1.4 -0.8 -1.2 -0.8 -1.9 -1.5 -0.3 -0.3 -0.2 -1.0 0.2 -0.1 -0.7 -0.2 1.2 -0.2 -0.5 -0.3 -1.1 -1.4 -0.2 -0.9 -0.6 -0.3 -0.3 -2.0
Deep venous thrombosis (DVT) (self-reported) 0.6 0.7 3.8 -0.9 -0.2 -0.4 0.7 0.1 -0.5 0.2 -0.7 -0.9 -0.4 -0.4 1.1 -1.3 -0.7 -0.3 -0.9 -0.5 -0.7 -1.0 -1.2 -0.5 -2.0 -0.5 -0.8 -0.9 -1.8 -0.6
Heart disease (siblings) 1.2 1.5 5.0 1.0 0.2 0.8 -0.4 1.2 -0.1 -0.5 1.7 2.0 1.3 0.8 -0.7 2.2 -0.3 1.2 0.5 1.3 1.5 1.5 0.9 0.5 2.2 0.2 1.1 1.8 1.6 0.4
Alcohol drinker status: Previous 0.5 0.5 1.3 -0.9 -0.5 -1.1 -0.7 -0.2 -0.8 -0.2 -0.9 -0.4 -0.8 -0.9 0.2 -0.9 -0.6 -0.2 0.6 -0.8 -0.8 -0.9 -0.7 -0.6 -0.6 -0.7 -1.0 -1.0 -1.1 -0.3
Pack years of smoking 4.2 6.2 9.3 2.7 2.6 2.7 2.2 2.4 2.6 2.5 2.4 2.7 1.9 2.6 3.1 2.3 2.4 2.3 -2.2 2.4 2.7 2.4 2.9 2.5 2.1 2.5 2.6 2.5 2.7 2.3
Impedance of whole body 0.8 4.3 9.9 2.0 3.0 1.9 2.7 1.9 2.6 1.8 1.4 1.0 1.2 2.4 1.1 0.9 2.5 1.7 -2.7 1.8 1.8 1.4 3.1 2.6 0.2 2.4 2.3 1.4 2.1 2.8
Leg fat mass (left) 1.1 4.1 8.5 -2.3 -2.1 -2.1 -1.8 -2.2 -1.8 -1.5 -1.9 -1.4 -2.1 -2.2 0.4 -1.5 -2.5 -1.6 1.6 -2.3 -1.9 -2.7 -2.9 -2.0 -1.5 -2.3 -2.1 -1.9 -2.5 -2.0
Arm predicted mass (left) 0.0 0.2 0.9 0.0 -0.4 -0.1 1.0 -0.1 0.2 0.9 -0.3 -0.4 -0.1 0.1 0.5 -0.8 0.9 -0.2 -0.7 0.1 -0.3 0.1 -0.1 0.4 -0.1 0.5 0.1 -0.5 0.2 0.0