Hub : Genes

RP3-486I3.5

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Artery Tibial 0.0956 0.0453 0.00200 0.004 NA 0.049 NA 0.009 0.16000 NA 9.7e-05 NA 0.05900
2 GTEx Muscle Skeletal 0.0777 0.0310 0.00037 0.037 NA 0.033 NA 0.027 0.00014 NA 2.9e-04 NA 0.00094

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 1.4 2.2 2.6 -1.3 1.6
Bipolar Disorder or Schizophrenia 0.6 1.5 2.8 -1.7 0.5
Depressed Affect (Nagel 2018) 0.6 1.2 1.9 0.7 -1.4
Depression (Nagel 2018) 0.5 0.7 1.4 -1.2 0.2
Intelligence (Savage-Jansen 2018) 0.7 2.2 2.8 -1.7 1.3
Neuroticism (Nagel 2018) 0.4 0.9 1.7 -0.2 -1.3
Schizophrenia (2018) 0.4 0.8 1.1 -1.1 -0.7
Schizophrenia vs Biploar Disorder 0.3 0.4 0.4 -0.7 -0.5
Worry (Nagel 2018) 0.5 1.1 2.2 -1.5 -0.1
Alzheimer’s Disease (in mother) 1.1 1.3 2.5 1.6 -0.4
Alzheimer’s Disease (in father) 0.4 0.4 0.8 -0.0 0.9
Alzheimer’s Disease (including proxy) 0.4 0.6 0.6 0.8 -0.7
Crohns Disease (2017) 0.1 0.2 0.3 0.1 -0.5
Irritable Bowel Disease (IBD) 0.0 0.1 0.1 -0.2 0.4
Ulcerative Colitis (UC) 0.3 0.5 0.8 -0.5 0.9
Major Depression (MDD) 0.5 0.6 1.1 -0.2 1.1
Reaction Time 0.2 0.3 0.6 0.2 -0.8
Verbal and Numeric Reasoning (VNR) 0.2 0.5 1.0 0.0 1.0
Breast Cancer 0.3 0.8 1.3 -0.5 -1.1
Ovarian Cancer 0.7 0.9 1.6 -1.2 0.6
Prostate Cancer 0.0 0.0 0.0 0.0 0.0
Age at First Birth 0.0 0.1 0.1 -0.2 -0.2
Bipolar Disorder (2011) 1.4 1.4 2.2 -0.7 1.5
Body Mass Index (BMI) (2010) 0.2 0.2 0.3 -0.4 -0.6
Coronary Artery Disease (CAD) 1.0 1.2 2.2 -1.5 0.5
Crohns Disease (2012) 0.1 0.1 0.2 0.0 -0.5
Mean Putamen Volume 2.5 2.8 4.1 1.2 -2.0
Fasting Glucose 0.7 0.9 1.2 -0.7 -1.1
HbA1C 0.5 0.6 1.0 0.3 1.0
HDL Cholesterol 1.1 1.9 2.3 -1.2 1.5
LDL Cholesterol 11.7 18.5 30.1 -2.6 5.5
Lupus 1.3 1.9 3.8 -0.0 -1.9
Neuroticism (2016) 0.8 1.2 2.3 0.4 1.5
Primary Biliary Cirrhosis 0.5 0.8 1.2 0.5 -1.1
Rheumatoid Arthritis 0.4 0.6 1.2 1.1 -0.2
Schizophrenia (2014) 0.4 0.8 1.5 -1.2 0.3
Triglycerides 2.7 4.5 5.5 -1.9 2.3
Type 2 Diabetes (T2D) (2012) 0.4 0.5 0.5 0.7 -0.7
Ulcerative Colitis 0.8 1.2 1.7 1.3 0.8
Blood Eosinophil Count 0.0 0.3 0.4 -0.7 0.4
Blood Platelet Count 0.0 0.1 0.1 0.3 -0.3
Blood Red Count 0.6 6.2 8.9 1.9 -3.0
Blood White Count 0.3 2.2 2.3 -1.5 1.5
Heel T-Score 0.0 0.1 0.1 -0.3 0.2
BMI 0.3 1.9 2.0 -1.4 -1.3
Height 2.9 56.4 69.2 6.6 -8.3
Waist Hip Ratio (WHR) 0.3 1.2 1.8 1.4 0.8
Systolic Blood Pressure 0.4 2.2 2.4 1.4 1.5
Smoking Status 1.0 2.3 4.7 2.2 -0.2
Allergy or Eczema 1.2 3.1 6.0 -0.5 2.4
Cardiovascular Disease 2.8 9.2 11.9 -2.5 3.5
Hypothyroidism (self reported) 0.2 0.4 0.8 0.3 -0.9
Respiratory disease 1.3 2.8 4.1 -1.2 2.0
Type 2 Diabetes (T2D) (2018) 0.1 0.2 0.3 0.4 0.5
Lung FEV1/FVC ratio 3.0 15.2 17.8 3.6 -4.2
Lung FVC 0.1 0.5 0.8 0.9 0.4
Neuroticism 0.5 1.2 2.4 0.0 -1.6
Chronotype (morning person) 0.3 0.8 1.2 0.6 1.1
Hair Pigment 0.1 4.0 6.0 1.5 -2.4
Tanning 0.0 0.0 0.0 -0.0 0.1
Hand grip strength (left) 1.0 2.6 5.1 2.3 -0.2
Number of treatments/medications taken 0.4 0.7 0.8 -0.7 0.9
Average weekly spirits intake 0.2 0.3 0.5 0.2 -0.7
Sensitivity / hurt feelings 0.3 0.6 1.1 -0.2 -1.1
Frequency of depressed mood in last 2 weeks 0.8 1.1 1.3 -1.2 0.9
Hearing difficulty/problems: Yes 1.0 1.5 3.0 -0.4 1.7
Relative age of first facial hair 0.6 1.3 2.6 -0.0 -1.6
Other serious medical condition/disability diagnosed by doctor 0.9 1.1 2.2 -1.5 -0.2
Ever used hormone-replacement therapy (HRT) 0.4 0.5 0.6 -0.8 0.6
Ever had hysterectomy (womb removed) 1.2 1.4 1.8 1.0 -1.3
Systolic blood pressure, automated reading 1.0 2.8 5.3 2.3 0.6
Eye problems/disorders: Diabetes related eye disease 0.1 0.1 0.3 -0.5 0.2
Angina 0.1 0.1 0.1 -0.4 -0.1
Medication for hormone replacement therapy 0.5 0.6 0.9 0.6 0.9
Vitamin and mineral supplements 1.6 2.2 3.9 -0.7 2.0
Supplements: Zinc 0.1 0.1 0.1 -0.4 0.4
Medication: Co-codamol 0.1 0.2 0.2 -0.4 0.4
Medication: Metformin 0.0 0.0 0.1 -0.2 -0.2
Diabetes (father) 0.1 0.1 0.1 0.4 -0.3
Diabetes (mother) 0.2 0.2 0.5 0.1 0.7
Severe depression (siblings) 0.1 0.1 0.2 -0.0 -0.5
Pack years adult smoking proportion 1.0 1.6 3.0 -0.4 -1.7
Impedance of leg (right) 1.0 4.8 6.9 2.6 -1.6
Leg fat-free mass (left) 0.4 2.1 4.1 0.3 -2.0
Trunk fat percentage 3.1 12.5 24.3 0.8 -4.9
Hand grip strength (right) 0.9 2.6 3.5 1.9 -1.3
Townsend deprivation index at recruitment 0.5 0.7 1.3 0.3 -1.1
Current tobacco smoking 1.2 2.0 3.8 2.0 0.4
Average weekly fortified wine intake 0.2 0.3 0.5 -0.2 -0.7
Maternal smoking around birth 0.3 0.4 0.6 0.7 -0.5
Fed-up feelings 0.2 0.4 0.6 0.5 -0.8
Frequency of unenthusiasm / disinterest in last 2 weeks 0.2 0.3 0.6 -0.8 0.1
Relative age voice broke 1.2 1.9 3.7 -1.9 -0.3
Taking other prescription medications 1.1 1.7 1.8 -1.3 1.4
Age when periods started (menarche) 1.5 3.7 7.2 -0.3 -2.7
Bilateral oophorectomy (both ovaries removed) 0.2 0.3 0.5 -0.2 -0.7
Heel bone mineral density (BMD) T-score, automated (left) 0.4 0.8 1.0 -1.0 0.8
Tinnitus: Yes, but not now, but have in the past 1.1 1.2 1.4 -1.0 -1.2
Qualifications: CSEs or equivalent 0.7 0.9 1.1 -0.8 -1.0
Serious illness, injury or assault to yourself 2.9 3.5 6.4 -2.5 0.8
High blood pressure 1.4 3.9 5.7 -1.4 2.4
Hayfever, allergic rhinitis or eczema 0.6 1.3 1.8 -0.9 1.3
Multivitamins +/- minerals 1.2 1.6 2.7 -0.7 -1.6
Stomach or abdominal pain in last month 1.0 1.3 1.8 0.9 -1.3
Supplements: Glucosamine 0.7 0.9 1.7 -0.1 1.3
Diverticular disease/diverticulitis (self-reported) 0.2 0.2 0.4 0.0 -0.6
Medication: Atenolol 0.7 0.9 1.7 0.3 -1.3
Medication: Levothyroxine sodium 0.0 0.1 0.1 -0.4 0.1
Sitting height 2.6 18.8 25.4 5.0 -3.5
Chronic bronchitis/emphysema (father) 1.3 1.5 2.0 1.4 -1.0
High blood pressure (mother) 0.6 0.9 1.7 -0.2 1.3
Body mass index (BMI) 0.2 0.9 1.2 -1.1 -0.7
Impedance of leg (left) 1.2 5.8 7.4 2.7 -2.0
Leg predicted mass (left) 0.4 2.1 4.0 0.4 -2.0
Trunk fat mass 2.5 10.9 20.3 1.2 -4.5
Waist circumference 0.2 0.6 1.2 0.1 -1.1
Number of incorrect matches in round 0.6 1.1 2.1 1.4 -0.2
Past tobacco smoking 0.2 0.5 0.5 -0.6 0.7
Alcohol usually taken with meals 0.5 0.7 1.1 0.6 1.1
Nervous feelings 2.1 3.9 5.2 -2.3 1.6
Frequency of tenseness / restlessness in last 2 weeks 1.2 1.9 2.2 -1.5 1.3
Hearing difficulty/problems with background noise 0.2 0.3 0.6 -0.7 0.4
Hair/balding pattern: Pattern 2 2.4 3.0 5.1 -2.3 -0.9
Had menopause 0.3 0.4 0.5 0.5 0.7
Had other major operations 0.3 0.3 0.7 -0.8 0.0
Forced vital capacity (FVC) 1.0 3.8 4.4 2.1 -1.8
Heel bone mineral density (BMD) T-score, automated (right) 0.0 0.0 0.1 0.3 0.1
Ever unenthusiastic/disinterested for a whole week 0.1 0.2 0.2 0.5 -0.3
Qualifications: None of the above 0.4 0.9 1.0 1.0 -0.8
Financial difficulties in last 2 years 0.3 0.5 0.7 -0.8 -0.5
Mouth/teeth dental problems 3.9 6.0 6.2 -2.4 2.5
Heart attack 0.3 0.4 0.6 0.5 0.8
Allergy 0.4 0.9 1.4 0.6 -1.2
Pain all over the body in last month 0.6 0.6 1.1 1.1 0.4
Diabetes (self-reported) 0.1 0.1 0.2 -0.5 0.2
Hayfever/allergic rhinitis (self-reported) 0.6 0.8 0.9 -0.8 1.0
Medication: Ramipril 0.1 0.1 0.1 -0.3 0.3
Medication: Simvastatin 2.9 4.3 6.8 -1.3 2.6
Fluid intelligence score 0.5 1.0 1.2 -0.9 1.1
Illnesses of siblings 0.9 1.3 2.5 0.2 -1.6
Neuroticism score 0.2 0.4 0.5 -0.5 -0.7
Weight 0.9 4.3 7.4 1.1 -2.7
Impedance of arm (right) 2.1 9.6 15.1 2.0 -3.9
Arm fat percentage (right) 0.7 2.7 5.3 -0.1 -2.3
Trunk fat-free mass 0.2 1.0 2.0 1.4 -0.2
Hip circumference 0.4 1.8 3.5 -0.3 -1.9
Time employed in main current job 1.8 2.1 3.5 0.9 -1.9
Alcohol intake versus 10 years previously 0.2 0.2 0.4 0.7 0.2
Father’s age at death 0.4 0.5 0.7 -0.9 0.5
Worrier / anxious feelings 0.5 0.9 1.6 -1.3 0.2
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.7 0.7 -0.8 -0.8
Falls in the last year 0.1 0.1 0.3 -0.2 0.5
Hair/balding pattern: Pattern 3 3.3 4.9 9.8 -0.0 3.1
Number of live births 1.6 2.2 4.3 2.1 -0.4
Forced expiratory volume in 1-second (FEV1) 1.7 5.9 6.3 2.3 -2.5
Pulse rate 0.3 0.5 0.7 -0.4 0.9
Happiness 1.1 1.3 2.7 -0.1 -1.6
Noisy workplace 1.5 1.9 2.2 1.5 -1.3
Qualifications: A levels/AS levels or equivalent 1.7 3.8 6.2 -2.5 1.2
Serious illness, injury or assault of a close relative in last 2 years 1.1 1.3 1.4 -1.1 1.2
Mouth/teeth dental problems: Dentures 3.1 5.3 5.6 2.4 -2.2
Asthma 1.3 2.5 4.9 -0.3 2.2
Medication: Ibuprofen (e.g. Nurofen) 0.0 0.0 0.0 -0.0 -0.1
Medication: Cholesterol lowering 3.0 4.7 6.0 -1.8 2.5
Depression (self-reported) 2.6 3.1 5.3 -0.9 2.3
Medication: Lansoprazole 0.2 0.3 0.3 0.5 -0.5
Prospective memory result 0.8 0.9 1.8 1.4 0.2
Lung cancer (father) 0.4 0.5 0.9 0.9 0.3
Illnesses of mother 1.6 2.0 3.6 -0.6 -1.9
Forced expiratory volume in 1-second (FEV1), Best measure 3.0 9.6 11.1 2.9 -3.3
Pulse wave Arterial Stiffness index 2.5 3.0 5.6 2.4 0.6
Impedance of arm (left) 3.0 13.9 23.9 2.0 -4.9
Arm fat mass (right) 0.8 3.4 6.7 0.3 -2.6
Trunk predicted mass 0.2 1.0 2.0 1.4 -0.2
Standing height 2.1 21.1 21.9 4.5 -4.7
Length of working week for main job 0.6 0.7 0.8 0.8 -0.9
Exposure to tobacco smoke at home 1.0 1.2 1.2 -1.1 -1.0
Breastfed as a baby 0.3 0.4 0.7 -0.4 0.8
Tense / ‘highly strung’ 0.5 0.9 1.7 -0.1 1.3
Seen doctor (GP) for nerves, anxiety, tension or depression 0.5 0.8 1.3 -0.5 1.1
Hair/balding pattern: Pattern 4 1.2 2.8 3.0 -1.7 1.6
Birth weight of first child 0.1 0.2 0.3 -0.6 0.4
Peak expiratory flow (PEF) 0.4 1.0 1.2 -0.9 1.1
Pulse wave reflection index 2.9 3.6 6.2 2.5 1.0
Ever highly irritable/argumentative for 2 days 0.8 1.0 1.9 1.4 0.3
Loud music exposure frequency 0.8 0.8 1.1 0.7 -1.1
Qualifications: O levels/GCSEs or equivalent 3.7 5.9 7.9 -2.8 2.0
Mouth/teeth dental problems: Bleeding gums 0.5 0.6 0.7 0.7 -0.9
Blood clot in the leg (DVT) 1.1 1.4 2.4 0.7 -1.6
Medication: Paracetamol 0.4 0.6 1.3 0.1 -1.1
Headache pain in last month 1.7 2.9 5.4 -2.3 0.6
Medication for cholesterol, blood pressure or diabetes 1.0 1.6 2.2 1.5 -1.0
Glaucoma (self-reported) 0.3 0.4 0.6 0.8 0.4
Gout (self-reported) 5.1 7.0 9.7 -2.1 3.1
Hypothyroidism/myxoedema (self-reported) 0.1 0.3 0.5 -0.3 -0.7
Medication: Amlodipine 2.5 3.5 6.5 -0.7 2.5
Medication: Ventolin 100micrograms inhaler 2.3 2.9 3.9 -1.4 2.0
Birth weight 0.7 1.5 2.8 0.5 -1.7
Chronic bronchitis/emphysema (mother) 1.8 2.1 3.9 -0.5 2.0
High blood pressure (siblings) 0.9 1.3 2.5 -0.4 1.6
Forced vital capacity (FVC), Best measure 1.9 7.0 7.3 2.7 -2.6
Body fat percentage 1.8 7.2 14.0 0.7 -3.7
Leg fat percentage (right) 0.5 1.7 3.2 0.4 -1.8
Arm fat-free mass (right) 0.2 0.9 1.1 0.8 -1.1
Exposure to tobacco smoke outside home 0.1 0.1 0.2 0.4 0.3
Comparative body size at age 10 1.5 4.1 7.6 -2.8 -0.8
Number of full brothers 1.8 2.2 3.7 1.9 0.8
Worry too long after embarrassment 1.8 3.0 5.5 0.7 -2.3
Seen a psychiatrist for nerves, anxiety, tension or depression 1.8 2.4 3.0 -1.7 1.4
Wheeze or whistling in the chest in last year 0.4 0.7 1.3 -1.1 -0.2
Number of children fathered 0.9 1.0 1.8 -0.4 -1.3
Reason for reducing amount of alcohol drunk: Health precaution 1.5 1.7 2.8 -1.7 -0.8
Age at first live birth 0.9 1.7 2.9 -1.7 -0.7
Pulse wave peak to peak time 2.2 2.6 3.7 -1.9 -1.2
Health satisfaction 0.1 0.1 0.2 -0.2 -0.4
Shortness of breath walking on level ground 0.7 0.9 1.5 -1.2 -0.5
Qualifications: College or University degree 0.8 2.6 4.5 -0.9 2.1
Eye problems/disorders: None of the above 0.3 0.4 0.6 -0.4 -0.8
Mouth/teeth dental problems: Loose teeth 0.3 0.4 0.7 0.3 -0.9
Emphysema/chronic bronchitis 2.2 2.5 5.0 -2.2 0.2
Medication for pain relief, constipation, heartburn 0.1 0.2 0.2 -0.5 0.3
Neck or shoulder pain in last month 4.5 6.5 12.2 -3.5 0.8
Medication: Blood pressure 0.1 0.2 0.3 -0.6 0.1
Angina (self-reported) 0.1 0.1 0.2 -0.4 -0.1
Migraine (self-reported) 0.2 0.3 0.5 0.3 -0.7
Medication: Ibuprofen 0.1 0.1 0.2 -0.4 0.0
Medication: Allopurinol 2.5 3.3 3.4 -1.8 1.8
Medication: Omeprazole 0.4 0.5 0.7 0.5 -0.8
Medication: Seretide 50 evohaler 0.7 0.8 1.3 -0.6 -1.1
Mean time to correctly identify matches 1.2 2.4 4.3 0.6 -2.1
Heart disease (mother) 0.3 0.3 0.6 0.8 -0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 2.5 2.9 4.8 1.0 2.2
Whole body fat mass 1.6 6.8 13.1 0.7 -3.6
Leg fat mass (right) 0.9 3.4 6.7 0.4 -2.6
Arm predicted mass (right) 0.2 1.1 1.3 1.0 -1.1
Pulse rate, automated reading 0.1 0.2 0.3 0.2 0.5
Alcohol intake frequency. 0.1 0.3 0.3 0.5 -0.5
Comparative height size at age 10 1.5 8.5 9.4 3.1 -2.8
Number of full sisters 3.8 4.6 7.3 -2.7 1.4
Suffer from ‘nerves’ 0.3 0.5 0.9 -1.0 0.3
Overall health rating 1.6 3.5 5.4 -2.3 1.3
Chest pain or discomfort 3.7 5.4 6.4 -2.1 2.5
Had major operations 2.4 2.8 2.8 -1.6 -1.7
Age at last live birth 0.4 0.6 1.2 -0.3 -1.1
Family relationship satisfaction 0.8 1.0 1.7 -0.6 -1.3
Leg pain on walking 1.5 1.8 3.0 -1.7 0.9
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.3 0.7 0.8 0.1
Commuting to job workplace: Car/motor vehicle 0.5 0.6 1.2 0.2 -1.1
Illness, injury, bereavement, stress in last 2 years 0.9 1.1 1.6 1.3 0.8
Medication: Aspirin 0.3 0.5 0.8 -0.9 -0.4
Supplements: Vitamin C 2.6 3.0 4.8 1.1 -2.2
Knee pain experienced in last month 0.4 0.7 0.8 -0.8 -0.9
Hypertension (Self-reported) 1.2 3.2 5.7 -0.9 2.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 3.0 3.5 6.1 1.0 -2.5
Illnesses of father: Heart disease 0.5 0.7 1.2 -1.1 -0.3
Illnesses of siblings: Diabetes 0.2 0.2 0.4 -0.1 0.6
Smoking status: Previous 0.5 0.7 1.1 -0.6 -1.1
Forced expiratory volume in 1-second (FEV1), predicted 0.9 1.9 3.5 0.6 -1.9
Whole body fat-free mass 0.2 0.9 0.9 0.9 -0.9
Leg fat-free mass (right) 0.4 1.9 3.7 0.4 -1.9
Arm fat percentage (left) 1.0 4.1 8.1 -0.2 -2.9
Average weekly red wine intake 3.1 4.5 7.2 -1.4 2.7
Handedness (chirality/laterality): Left-handed 1.6 1.9 3.8 1.9 0.0
Mood swings 0.0 0.1 0.1 0.3 -0.2
Loneliness, isolation 0.3 0.4 0.6 0.8 0.4
Long-standing illness, disability or infirmity 0.7 1.0 1.8 -1.4 0.4
Ever had bowel cancer screening 0.3 0.4 0.6 0.8 0.5
Diabetes diagnosed by doctor 0.0 0.0 0.1 -0.3 0.0
Ever had stillbirth, spontaneous miscarriage or termination 0.9 1.0 1.9 1.4 0.3
Friendships satisfaction 0.9 1.2 2.3 -0.2 1.5
Qualifications: nursing, teaching 0.6 0.9 1.0 -0.9 1.0
Commuting to job workplace: Walk 2.5 2.7 4.2 -1.1 2.1
Eye problems/disorders: Cataract 1.0 1.2 2.0 0.7 1.4
Mouth/teeth dental problems: Mouth ulcers 0.7 1.1 1.8 1.3 -0.7
Medication for cholesterol 2.4 3.6 7.1 -0.4 -2.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.6 0.7 1.3 -1.2 0.4
Back pain experienced in last month 1.4 2.1 4.2 -2.0 -0.2
Mineral and other dietary supplements 0.5 0.6 1.2 -0.3 -1.1
Breast cancer (self-reported) 3.9 4.6 8.9 -0.6 3.0
Asthma (self-reported) 1.1 2.2 4.0 -0.6 2.0
Osteoporosis (self-reported) 0.5 0.6 0.6 0.8 -0.8
Osteoarthritis (self-reported) 0.4 0.5 0.9 -0.3 1.0
Medication: Aspirin 0.4 0.6 1.1 -1.1 0.1
Medication: Gliclazide 0.1 0.1 0.2 -0.1 -0.4
Illnesses of father: None of the above (group 1) 0.0 0.0 0.0 0.1 0.1
Smoking status: Current 1.7 2.7 5.0 2.2 0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.5 3.2 4.3 1.5 -2.1
Whole body water mass 0.1 0.8 0.8 0.9 -0.9
Leg predicted mass (right) 0.4 2.2 4.3 0.4 -2.1
Arm fat mass (left) 0.9 3.9 7.7 0.2 -2.8
Number of self-reported non-cancer illnesses 1.8 3.1 3.9 -1.5 2.0
Average weekly champagne plus white wine intake 0.6 0.8 0.9 0.8 -0.9
Miserableness 0.0 0.0 0.1 -0.3 0.1
Guilty feelings 0.2 0.2 0.3 0.4 0.6
Wears glasses or contact lenses 2.2 2.5 3.2 1.3 -1.8
Ever taken oral contraceptive pill 0.6 0.7 1.2 -1.1 0.3
Hearing aid user 0.7 0.8 1.4 1.2 0.5
Mother’s age at death 0.1 0.1 0.1 0.2 0.3
Financial situation satisfaction 0.0 0.1 0.1 0.3 0.2
Tinnitus: Yes, now most or all of the time 0.4 0.4 0.8 -0.1 -0.9
Commuting to job workplace: Public transport 0.0 0.0 0.0 -0.0 -0.0
Eye problems/disorders: Glaucoma 0.2 0.3 0.6 0.8 -0.1
Medication: Blood pressure 0.5 0.9 0.9 -1.0 1.0
Pain type(s) experienced in last month: Hip pain 0.7 0.9 1.1 -0.9 1.1
Supplements: Fish oil (including cod liver oil) 0.5 0.7 1.3 1.1 -0.4
High cholesterol (Self-reported) 4.3 7.7 14.2 -1.1 3.8
Medication: Bendroflumethiazide 0.2 0.3 0.5 -0.7 0.1
Medication: Paracetamol 0.1 0.2 0.3 0.0 -0.6
Medication: Lisinopril 0.0 0.1 0.1 -0.1 0.3
Medication: Atorvastatin 0.2 0.3 0.5 -0.2 0.7
Illnesses of father: High blood pressure 0.0 0.0 0.0 -0.1 0.1
Alcohol drinker status: Never 1.3 1.6 1.7 -1.2 -1.3
Ever smoked 0.3 0.5 1.1 1.0 -0.2
Basal metabolic rate 0.3 1.5 2.0 1.0 -1.4
Leg fat percentage (left) 0.5 1.7 3.3 0.4 -1.8
Arm fat-free mass (left) 0.1 0.5 0.9 0.9 -0.4
Number of operations (self-reported) 0.5 0.8 0.8 -0.9 -0.9
Average weekly beer plus cider intake 0.1 0.2 0.3 0.1 -0.5
Irritability 1.3 2.3 4.5 0.3 -2.1
Risk taking 0.6 0.9 1.8 0.2 -1.4
Ever had prostate specific antigen (PSA) test 0.1 0.1 0.1 -0.4 0.3
Fractured/broken bones in last 5 years 0.7 0.9 1.8 -0.1 -1.3
Age started oral contraceptive pill 1.9 2.4 4.7 -2.2 -0.1
Diastolic blood pressure, automated reading 2.0 6.2 12.4 -0.0 3.5
Ever depressed for a whole week 0.2 0.3 0.4 -0.6 -0.4
Unable to work because of sickness or disability 1.0 1.3 1.4 -1.1 1.2
Commuting to job workplace: Cycle 0.5 0.6 1.3 0.0 1.1
Myopia 5.4 7.9 14.7 1.0 -3.8
Vascular/heart problems diagnosed by doctor 1.3 3.5 5.6 1.2 -2.4
Cholesterol lowering medication 0.4 0.6 0.9 0.5 1.0
Medication: Omeprazole (e.g. Zanprol) 1.8 2.2 2.2 1.5 -1.5
Pain experienced in last month 2.7 4.5 8.6 2.9 -0.6
Supplements: Calcium 0.6 0.6 1.0 -1.0 0.5
Basal cell carcinoma (self-reported) 0.3 0.3 0.5 -0.7 -0.4
Heart attack/myocardial infarction (self-reported) 0.3 0.4 0.5 0.6 0.7
Deep venous thrombosis (DVT) (self-reported) 0.6 0.8 1.0 0.7 -1.0
Heart disease (siblings) 0.4 0.5 0.6 -0.7 0.8
Alcohol drinker status: Previous 0.4 0.4 0.9 -0.0 -0.9
Pack years of smoking 0.9 1.3 2.4 -0.5 -1.6
Impedance of whole body 2.0 10.3 15.3 2.3 -3.9
Leg fat mass (left) 0.9 3.4 6.7 0.4 -2.6
Arm predicted mass (left) 0.2 1.0 1.6 1.2 -0.6