Hub : Genes

SLC10A7

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1070	0.0390	3.2e-03	0.013	NA	-0.003	NA	-0.003	2.9e-02	NA	7.2e-01	NA	6.5e-01
2	GTEx	Esophagus Mucosa	0.2230	0.0590	3.2e-04	0.156	NA	0.144	NA	0.147	1.3e-10	NA	7.6e-10	NA	4.9e-10
3	GTEx	Thyroid	0.1340	0.0530	5.7e-03	0.021	NA	0.049	NA	0.031	9.1e-03	NA	1.2e-04	NA	1.8e-03
4	TCGA	Breast Invasive Carcinoma	0.0647	0.0264	6.6e-06	0.033	0.016	0.020	NA	0.025	1.6e-07	2.5e-04	3.8e-05	NA	5.7e-06
5	TCGA	Brain Lower Grade Glioma	0.1540	0.0464	6.9e-07	0.094	0.069	0.095	NA	0.104	7.5e-11	3.0e-08	5.9e-11	NA	7.7e-12
6	TCGA	Lung Adenocarcinoma	0.0418	0.0252	7.0e-03	0.000	0.007	0.006	NA	-0.002	3.4e-01	4.8e-02	5.7e-02	NA	7.6e-01
7	TCGA	Prostate Adenocarcinoma	0.0393	0.0196	7.2e-04	0.027	0.033	0.037	NA	0.035	6.4e-04	1.8e-04	8.8e-05	NA	1.2e-04
8	TCGA	Skin Cutaneous Melanoma	0.3110	0.1330	9.2e-03	0.034	0.073	0.043	NA	0.100	4.3e-02	5.2e-03	2.7e-02	NA	1.3e-03
9	TCGA	Thyroid Carcinoma	0.1310	0.0520	1.6e-04	0.073	0.027	0.050	NA	0.049	1.4e-07	1.0e-03	1.2e-05	NA	1.5e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	2.3	3.7	12.8	0.1	-2.0	-0.6	1.7	1.4	3.6	2.2	1.6	1.8
Bipolar Disorder or Schizophrenia	0.7	1.8	4.8	0.4	0.2	-0.7	1.6	1.5	2.2	1.0	1.2	1.9
Depressed Affect (Nagel 2018)	0.4	0.9	3.4	0.6	-0.0	1.8	-0.7	0.2	-0.1	-1.3	1.4	-0.0
Depression (Nagel 2018)	0.5	0.8	3.4	-0.1	0.4	0.6	0.0	0.8	-1.1	-1.0	1.9	0.3
Intelligence (Savage-Jansen 2018)	0.2	0.8	2.7	1.3	-1.0	-0.9	-0.0	-0.1	-0.6	0.3	-1.6	-0.4
Neuroticism (Nagel 2018)	0.4	0.9	2.9	0.4	-0.4	1.0	-1.3	-0.3	-0.4	-1.5	1.7	-0.4
Schizophrenia (2018)	0.3	0.7	3.8	0.4	1.9	-0.5	0.6	0.8	-0.1	-0.4	0.3	1.0
Schizophrenia vs Biploar Disorder	1.3	1.7	6.5	-0.4	1.2	0.8	0.4	0.1	-2.6	-0.5	-2.4	-0.0
Worry (Nagel 2018)	0.6	1.2	2.8	-0.9	-1.2	-0.0	-1.7	-1.0	-0.9	-1.4	1.1	-0.9
Alzheimer’s Disease (in mother)	1.0	1.2	5.0	0.6	-1.3	-0.7	0.8	0.2	1.4	2.2	0.8	0.4
Alzheimer’s Disease (in father)	3.0	3.3	7.5	-1.6	-0.1	-0.8	-2.7	-2.4	-1.8	-2.1	0.4	-2.4
Alzheimer’s Disease (including proxy)	1.8	2.6	6.1	-0.3	-0.5	-1.8	-2.3	-2.5	-1.4	-0.4	0.8	-2.3
Crohns Disease (2017)	0.6	1.3	2.4	-1.2	-1.0	1.2	1.5	1.2	0.4	0.6	1.1	1.5
Irritable Bowel Disease (IBD)	0.3	0.7	1.9	-0.8	-0.6	0.5	1.3	1.1	0.3	0.2	-0.1	1.4
Ulcerative Colitis (UC)	0.2	0.4	1.0	0.2	-0.1	-0.3	0.7	0.7	0.4	0.0	-1.0	1.0
Major Depression (MDD)	0.8	0.9	3.4	1.1	0.9	-1.3	0.4	0.7	-0.1	-0.6	1.9	0.6
Reaction Time	0.2	0.4	1.5	0.9	0.5	-0.5	-0.4	-0.2	1.2	-0.4	0.8	0.3
Verbal and Numeric Reasoning (VNR)	0.3	0.6	1.7	1.3	-1.1	-0.8	-0.2	-0.0	-0.6	-0.6	-1.1	-0.1
Breast Cancer	0.6	1.5	8.9	0.8	-0.7	-0.0	0.2	-0.6	-0.2	1.4	-3.0	-0.9
Ovarian Cancer	0.8	1.1	2.0	-0.1	-1.0	-0.0	1.4	1.2	1.4	1.2	1.0	1.1
Prostate Cancer	1.5	2.2	6.2	-1.3	-0.4	0.5	-0.9	-0.4	-2.5	-2.4	2.1	-0.3
Age at First Birth	0.6	0.9	3.6	-0.8	-1.9	0.2	-0.6	-1.3	-0.2	0.8	0.2	-1.0
Bipolar Disorder (2011)	0.8	0.8	3.3	-1.8	0.0	0.2	0.4	0.8	1.0	-0.7	-0.2	1.1
Body Mass Index (BMI) (2010)	2.2	3.0	7.1	0.9	0.1	-0.0	2.3	2.2	2.5	0.8	1.5	2.7
Coronary Artery Disease (CAD)	0.8	1.0	2.7	0.5	0.1	-1.6	-1.4	-1.4	0.4	-0.0	0.1	-1.3
Crohns Disease (2012)	1.1	1.7	3.7	-1.1	-0.1	0.8	1.9	1.3	0.9	1.2	1.8	1.6
Mean Putamen Volume	0.3	0.4	0.8	0.8	-0.9	0.1	0.7	0.7	-0.2	0.1	-0.3	0.7
Fasting Glucose	0.6	0.7	2.6	1.0	1.6	-0.0	-0.1	-0.2	-0.8	-0.3	1.2	-0.2
HbA1C	0.9	1.0	5.0	-0.6	-0.8	0.7	0.7	0.4	1.1	2.2	-0.1	0.8
HDL Cholesterol	0.1	0.2	0.7	-0.6	0.5	0.8	0.1	-0.2	0.0	0.5	-0.5	-0.3
LDL Cholesterol	0.5	0.8	3.1	0.3	-0.3	-0.3	0.5	0.9	1.3	0.0	1.8	1.1
Lupus	0.5	0.8	3.5	-1.9	0.4	-0.6	0.3	0.2	0.6	-0.3	1.4	0.6
Neuroticism (2016)	0.3	0.4	0.8	0.6	-0.9	0.8	0.3	0.8	0.5	-0.7	0.4	0.8
Primary Biliary Cirrhosis	0.6	0.8	3.0	-1.7	-0.8	-0.7	-0.4	-0.7	-0.1	0.9	-1.1	-0.9
Rheumatoid Arthritis	1.8	2.5	8.4	-0.5	-1.6	0.0	-1.4	-1.0	-2.9	-2.3	1.2	-0.9
Schizophrenia (2014)	1.1	2.4	5.6	0.9	0.9	0.6	2.3	2.2	1.5	1.1	0.4	2.4
Triglycerides	1.4	2.3	6.1	1.1	0.1	-0.5	1.7	1.3	2.5	1.8	1.3	1.9
Type 2 Diabetes (T2D) (2012)	0.9	1.1	3.4	0.9	0.5	1.0	1.4	1.2	0.3	0.5	-1.8	0.9
Ulcerative Colitis	0.2	0.3	0.7	0.2	-0.3	-0.1	0.8	0.8	0.4	0.1	-0.8	0.8
Blood Eosinophil Count	0.1	0.9	3.8	0.5	0.4	0.7	-0.3	0.7	0.6	-1.6	2.0	0.6
Blood Platelet Count	0.2	2.6	9.5	-0.2	1.4	-0.1	1.3	1.3	2.2	1.1	3.1	1.4
Blood Red Count	0.1	0.6	1.5	1.2	-0.8	-0.1	0.7	0.6	0.6	0.4	1.2	0.3
Blood White Count	0.4	2.7	11.5	-0.9	1.8	-0.2	1.2	1.3	1.9	1.1	3.4	1.1
Heel T-Score	0.9	7.3	25.8	1.6	-2.9	-5.1	1.3	0.1	2.9	3.8	-2.2	-0.5
BMI	1.7	9.9	22.1	0.5	-1.8	1.7	4.2	4.7	3.8	1.7	2.7	4.3
Height	0.3	5.5	14.1	0.5	1.6	1.9	-3.3	-2.1	-3.0	-3.8	-0.7	-2.1
Waist Hip Ratio (WHR)	0.2	0.8	3.3	1.3	1.8	-0.1	-0.1	0.4	-0.9	-1.0	0.1	-0.2
Systolic Blood Pressure	0.2	1.1	3.9	-2.0	-0.9	-0.9	-0.4	-0.5	-1.0	0.4	-0.8	-1.5
Smoking Status	1.2	2.9	13.4	-2.0	3.7	0.1	-1.8	-1.3	0.0	-1.1	1.1	-1.3
Allergy or Eczema	2.1	5.6	13.1	0.0	-0.4	0.5	3.6	3.0	2.6	3.1	0.8	3.3
Cardiovascular Disease	0.7	2.3	4.8	0.0	-1.7	0.1	2.1	1.7	1.0	2.2	1.9	1.2
Hypothyroidism (self reported)	0.1	0.1	0.5	0.3	0.1	0.1	-0.4	-0.2	-0.4	-0.7	0.2	-0.2
Respiratory disease	0.4	1.0	1.9	0.2	-1.0	0.7	1.1	1.1	1.1	0.4	1.2	1.4
Type 2 Diabetes (T2D) (2018)	0.3	0.5	1.2	0.4	-0.2	0.1	0.8	0.9	0.8	0.1	1.0	1.1
Lung FEV1/FVC ratio	2.0	10.0	24.5	0.7	-0.7	1.9	4.3	4.4	5.0	2.7	-0.0	4.0
Lung FVC	1.2	5.9	13.2	-0.7	-1.0	3.4	2.5	1.9	3.6	3.2	1.3	2.2
Neuroticism	0.3	0.7	1.4	1.1	-0.7	0.5	-1.1	-0.2	0.5	-1.1	1.2	-0.4
Chronotype (morning person)	1.6	3.8	15.8	-1.5	-0.0	-0.8	-1.9	-1.8	-4.0	-1.9	-0.5	-2.2
Hair Pigment	0.1	1.5	3.6	-0.7	1.2	-1.3	-1.5	-1.9	0.1	0.5	-0.1	-1.9
Tanning	0.1	0.8	2.3	-0.5	0.1	0.8	1.1	0.7	0.9	1.5	-0.8	0.6
Hand grip strength (left)	0.6	1.7	5.2	1.0	1.4	-0.9	-1.1	-0.8	-2.3	-1.1	-1.5	-1.1
Number of treatments/medications taken	1.2	2.1	4.7	-1.3	-2.2	-1.1	-1.4	-1.4	-1.5	-0.7	1.6	-1.3
Average weekly spirits intake	0.8	1.0	4.2	0.0	-0.5	-0.3	-0.8	-1.2	-0.2	1.1	-2.1	-1.1
Sensitivity / hurt feelings	0.2	0.4	1.4	-0.3	-0.2	0.2	-1.2	-0.5	0.6	-0.8	0.5	-0.5
Frequency of depressed mood in last 2 weeks	0.9	1.3	3.5	-0.3	-0.2	0.0	-1.5	-1.2	-1.9	-1.1	0.9	-1.6
Hearing difficulty/problems: Yes	0.5	0.8	3.1	-0.1	-1.7	-0.5	-0.1	0.4	-0.5	-1.5	0.8	0.5
Relative age of first facial hair	0.4	0.9	5.0	-0.1	2.2	1.2	0.6	0.8	-0.2	-0.1	0.7	0.4
Other serious medical condition/disability diagnosed by doctor	1.3	1.7	4.5	-1.4	-0.3	-1.8	-0.7	-1.7	0.5	2.1	-0.5	-1.3
Ever used hormone-replacement therapy (HRT)	1.2	1.6	2.9	1.6	-1.0	0.9	1.7	1.1	1.1	1.5	-0.0	1.5
Ever had hysterectomy (womb removed)	0.3	0.3	1.5	0.0	-0.9	0.0	-0.2	0.1	-0.3	-1.2	0.3	0.5
Systolic blood pressure, automated reading	0.5	1.4	2.9	-1.7	-1.2	-1.6	-0.8	-1.3	-0.6	0.5	0.7	-1.4
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	3.8	-1.6	-1.9	0.6	0.7	1.1	-0.9	-0.9	0.6	1.1
Angina	3.3	4.4	9.1	-0.5	-0.1	-2.3	-2.9	-1.9	-2.8	-3.0	-0.1	-2.2
Medication for hormone replacement therapy	0.3	0.4	1.8	0.2	-1.3	0.4	0.6	0.7	-0.2	0.5	0.4	0.3
Vitamin and mineral supplements	1.1	1.4	4.2	0.7	-0.3	0.9	1.3	2.0	0.7	-1.3	-0.5	1.8
Supplements: Zinc	1.5	1.7	6.0	-1.0	-0.0	-2.4	-1.3	-1.7	1.2	0.8	0.4	-1.3
Medication: Co-codamol	0.8	1.0	3.8	-0.1	0.1	-1.1	0.3	0.7	1.0	-0.8	1.9	1.3
Medication: Metformin	0.6	0.9	2.6	0.4	0.8	-0.7	0.7	0.6	1.6	0.5	1.2	1.3
Diabetes (father)	1.2	1.5	4.0	0.3	-2.0	0.2	1.1	1.0	1.8	1.7	0.8	0.5
Diabetes (mother)	0.6	0.7	3.1	-0.5	-0.0	1.8	-0.3	-0.0	-0.8	-0.5	1.3	-0.6
Severe depression (siblings)	1.6	1.8	3.8	1.5	-0.4	-1.2	-2.0	-1.9	-0.5	-0.6	1.4	-1.7
Pack years adult smoking proportion	0.6	1.0	3.3	1.8	-0.9	0.6	1.0	1.1	1.0	0.4	0.2	0.9
Impedance of leg (right)	0.2	1.0	3.1	-0.5	-0.3	-0.5	-1.4	-1.8	-0.4	0.1	-1.1	-1.3
Leg fat-free mass (left)	0.7	3.5	9.2	1.0	1.2	2.8	1.7	3.0	0.6	-1.3	1.7	2.1
Trunk fat percentage	1.0	4.0	9.6	-0.9	-1.2	2.5	2.3	3.1	1.2	-0.6	2.0	2.6
Hand grip strength (right)	0.5	1.3	4.6	1.2	1.3	-0.7	-0.9	-0.8	-2.1	-0.9	-0.6	-1.0
Townsend deprivation index at recruitment	1.1	1.6	6.2	-1.6	-1.8	2.5	0.6	0.6	-1.2	-0.2	-0.2	0.1
Current tobacco smoking	0.4	0.6	3.4	-0.8	1.9	0.2	-0.3	-0.2	-0.2	-0.2	1.0	-0.2
Average weekly fortified wine intake	1.6	1.8	6.9	0.1	-0.6	-1.5	-0.1	-1.2	0.9	2.6	-2.0	-0.9
Maternal smoking around birth	0.9	1.3	7.1	0.8	1.7	-0.2	0.0	-0.0	1.0	0.2	2.7	0.2
Fed-up feelings	0.5	0.9	3.5	0.2	-1.1	1.1	-0.6	0.3	-1.1	-1.9	-0.1	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	1.0	2.5	-0.6	0.6	1.2	-0.3	0.5	-1.4	-1.3	1.6	-0.1
Relative age voice broke	0.2	0.2	0.6	0.7	0.0	0.5	0.5	0.0	0.4	0.6	0.7	0.4
Taking other prescription medications	0.1	0.2	0.7	-0.5	-0.8	0.1	-0.2	-0.5	-0.8	-0.3	0.0	-0.3
Age when periods started (menarche)	0.3	0.7	1.6	0.4	1.0	-0.4	-1.3	-1.0	-0.2	0.1	1.2	-1.0
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	3.1	-0.5	-0.9	-1.8	-0.8	-0.9	-0.3	-0.4	0.6	-0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	7.3	-0.4	-0.8	-2.7	0.0	0.0	0.5	0.7	-1.1	-0.5
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.3	0.5	0.1	0.2	-0.4	-0.3	-0.1	0.1	-0.6	-0.4
Qualifications: CSEs or equivalent	1.0	1.4	2.8	-1.3	1.7	0.7	-1.0	-0.6	-1.5	-1.1	-1.1	-1.0
Serious illness, injury or assault to yourself	0.8	1.0	2.8	0.5	0.2	-0.4	1.2	1.0	1.7	1.2	0.6	1.3
High blood pressure	0.4	1.0	4.4	-1.0	-2.1	-0.8	0.1	0.0	0.3	0.7	1.5	-0.3
Hayfever, allergic rhinitis or eczema	1.9	4.0	9.1	0.6	-0.2	1.0	3.0	2.8	2.0	2.2	0.9	2.9
Multivitamins +/- minerals	0.6	0.8	4.7	0.7	0.7	0.0	-0.0	-0.8	0.6	2.2	-0.2	-0.5
Stomach or abdominal pain in last month	1.3	1.6	4.2	1.2	-0.5	1.2	1.5	1.2	1.6	2.1	0.4	1.0
Supplements: Glucosamine	1.0	1.3	6.4	0.3	-1.1	-0.1	0.2	-0.7	1.5	2.5	-0.8	-0.3
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	4.6	-0.7	-0.3	-0.4	0.8	0.7	2.2	1.4	0.8	0.5
Medication: Atenolol	0.4	0.5	1.6	-0.4	-0.3	-0.8	-0.6	-0.8	-1.2	-0.3	-0.2	-1.0
Medication: Levothyroxine sodium	0.3	0.5	2.4	0.7	0.8	0.9	-0.8	0.1	-0.1	-1.5	0.0	0.1
Sitting height	0.1	0.4	1.0	0.1	1.0	0.5	0.5	1.0	0.5	-0.1	0.6	0.4
Chronic bronchitis/emphysema (father)	1.8	2.1	4.6	1.4	1.1	0.9	1.7	1.4	2.1	1.6	-0.5	1.7
High blood pressure (mother)	1.7	2.4	5.7	-2.1	-1.0	-1.3	-1.4	-0.7	-1.1	-2.4	2.3	-0.6
Body mass index (BMI)	1.1	4.6	11.1	0.0	-0.7	1.5	2.7	3.3	2.0	0.1	2.9	2.8
Impedance of leg (left)	0.2	1.1	2.8	-0.9	-0.7	-0.7	-1.2	-1.6	-0.5	0.2	-1.7	-1.1
Leg predicted mass (left)	0.7	3.5	9.0	1.0	1.2	2.9	1.6	3.0	0.5	-1.3	1.6	2.0
Trunk fat mass	1.0	4.1	10.8	-0.6	-0.5	2.8	2.2	3.3	1.1	-0.8	2.1	2.6
Waist circumference	0.8	2.7	7.1	0.3	-0.3	2.0	1.6	2.7	0.6	-1.0	2.3	2.0
Number of incorrect matches in round	0.8	1.3	2.4	-0.7	0.2	1.5	1.4	1.6	1.1	0.3	1.2	1.5
Past tobacco smoking	0.6	1.2	3.2	0.5	-1.8	-0.4	1.3	0.7	0.4	1.3	-1.4	0.9
Alcohol usually taken with meals	0.6	1.0	3.5	0.8	-0.4	-0.3	0.8	0.0	1.3	1.9	-1.4	-0.0
Nervous feelings	1.0	1.9	4.2	-1.9	-0.4	0.2	-2.0	-1.9	-0.8	-0.3	0.8	-2.1
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	1.7	0.2	0.8	0.1	-1.3	-0.7	-1.3	-1.1	0.9	-1.2
Hearing difficulty/problems with background noise	0.8	1.2	3.5	-0.7	0.1	0.2	-1.3	-1.2	-1.9	-1.0	-0.9	-1.5
Hair/balding pattern: Pattern 2	1.3	1.7	3.2	1.5	-0.7	-1.4	1.8	1.2	0.7	1.7	-0.8	1.4
Had menopause	0.9	1.1	4.8	-1.2	-2.2	-0.4	-0.6	-0.8	-0.9	-0.3	1.0	-0.7
Had other major operations	3.9	4.8	9.2	0.6	-1.4	1.9	3.0	2.5	2.8	2.4	0.7	2.8
Forced vital capacity (FVC)	0.8	3.2	13.0	0.1	0.7	3.6	1.7	2.4	1.6	0.5	-0.2	2.1
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.5	9.7	-0.4	-0.9	-3.1	-0.6	-0.7	0.3	0.7	-0.7	-1.0
Ever unenthusiastic/disinterested for a whole week	2.8	3.5	8.1	-1.8	0.6	-1.6	-2.8	-2.1	-1.6	-1.9	-0.8	-2.3
Qualifications: None of the above	1.0	2.2	5.1	-1.1	0.4	-0.5	-1.9	-1.5	-1.5	-2.3	1.9	-1.3
Financial difficulties in last 2 years	0.5	0.7	2.4	1.0	0.8	0.3	0.5	0.4	0.9	0.7	1.6	0.3
Mouth/teeth dental problems	0.2	0.2	1.1	-0.4	-0.0	-0.2	0.6	0.3	0.2	0.4	-1.1	0.4
Heart attack	3.8	4.8	9.2	-0.2	1.0	-2.7	-2.8	-2.8	-2.8	-1.5	0.5	-3.0
Allergy	0.7	1.6	3.7	0.0	0.6	-1.1	-1.6	-1.9	-1.0	-0.4	-1.3	-1.9
Pain all over the body in last month	1.1	1.2	2.1	-0.8	0.2	1.2	1.5	1.5	1.3	0.9	-0.1	1.4
Diabetes (self-reported)	0.2	0.4	0.9	0.9	0.0	0.7	0.1	0.3	-0.4	-0.9	0.6	0.8
Hayfever/allergic rhinitis (self-reported)	1.6	2.1	5.1	0.3	-0.3	0.3	2.0	1.7	2.2	1.9	-0.4	1.7
Medication: Ramipril	1.9	2.5	5.1	-0.5	1.6	-1.5	-2.3	-2.1	-0.8	-1.1	0.8	-2.2
Medication: Simvastatin	0.5	0.7	4.2	0.8	-2.1	0.2	-0.2	0.0	-0.2	-0.6	1.1	0.2
Fluid intelligence score	0.4	0.7	2.0	0.7	-0.7	-1.1	-0.3	-0.9	-0.2	1.0	-1.4	-0.8
Illnesses of siblings	1.0	1.4	7.6	-0.8	1.6	0.9	0.6	0.4	-0.0	0.2	-2.8	0.1
Neuroticism score	0.2	0.5	1.9	0.3	-0.7	0.6	-0.9	-0.1	-0.6	-1.4	0.8	-0.3
Weight	0.7	3.6	9.3	0.2	0.1	2.6	1.8	3.0	0.9	-1.1	2.5	2.2
Impedance of arm (right)	0.1	0.4	1.4	0.1	-0.7	1.2	-0.2	-0.4	0.3	0.1	-1.2	0.2
Arm fat percentage (right)	1.6	6.5	14.5	-0.0	-1.1	2.8	3.1	3.8	2.3	0.1	3.0	3.4
Trunk fat-free mass	0.4	2.1	6.6	1.1	2.6	2.0	0.1	1.5	-0.1	-1.6	1.2	0.6
Hip circumference	0.6	2.4	6.6	0.5	-0.4	1.7	1.6	2.6	0.9	-0.9	2.1	1.9
Time employed in main current job	0.6	0.7	1.7	-0.5	-0.1	-0.2	1.0	0.8	0.9	0.8	1.3	1.2
Alcohol intake versus 10 years previously	0.3	0.5	1.8	-0.4	-1.4	0.6	0.9	0.9	-0.5	0.5	-0.1	0.2
Father’s age at death	0.4	0.5	2.2	0.6	0.4	0.1	0.7	0.7	-0.3	0.2	1.5	0.7
Worrier / anxious feelings	0.6	1.1	3.7	-0.2	-1.0	1.2	-0.4	0.6	-1.4	-1.9	-1.1	0.1
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	1.9	0.6	-1.3	1.1	0.7	1.3	-0.6	-0.6	1.4	1.3
Falls in the last year	0.4	0.5	2.4	-0.9	0.3	0.2	0.2	0.2	-1.2	-0.2	1.6	-0.2
Hair/balding pattern: Pattern 3	0.4	0.6	1.4	-0.7	0.9	0.1	-1.2	-0.7	-0.6	-1.1	-0.6	-0.8
Number of live births	1.9	2.7	5.7	1.6	0.2	1.6	2.2	2.1	1.8	1.2	-0.1	2.4
Forced expiratory volume in 1-second (FEV1)	1.8	5.9	14.5	0.5	0.4	3.8	2.9	3.5	2.6	1.2	-0.7	3.1
Pulse rate	3.6	6.0	17.9	1.1	-0.8	0.6	3.1	2.7	4.2	2.9	0.5	2.9
Happiness	0.4	0.5	2.0	-1.4	0.4	0.2	-0.9	-0.7	-0.3	-0.4	0.7	-0.8
Noisy workplace	1.2	1.5	3.4	-0.1	-0.6	1.3	1.3	1.7	0.6	-0.3	1.7	1.8
Qualifications: A levels/AS levels or equivalent	0.8	1.7	3.1	1.8	-0.6	0.6	1.3	1.7	1.4	0.5	-1.6	1.3
Serious illness, injury or assault of a close relative in last 2 years	1.5	1.7	5.5	-0.7	-1.4	-1.2	1.1	1.1	2.3	0.7	0.2	1.8
Mouth/teeth dental problems: Dentures	0.3	0.5	2.1	-0.7	0.4	-0.4	0.3	-0.4	1.0	1.4	0.1	-0.1
Asthma	0.3	0.6	3.1	-0.4	-0.6	1.8	0.4	0.5	-0.1	-0.3	1.1	0.6
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	1.3	-0.9	-0.4	0.5	0.0	-0.3	0.1	1.1	-0.4	-0.4
Medication: Cholesterol lowering	0.9	1.4	2.5	0.5	-0.0	-1.6	-1.4	-1.3	-1.5	-1.0	1.3	-1.1
Depression (self-reported)	1.7	2.0	4.3	-0.6	0.4	-0.9	-1.8	-1.7	-1.9	-0.9	-1.5	-2.1
Medication: Lansoprazole	0.5	0.5	1.4	-0.8	-0.4	1.2	0.8	0.8	-0.4	-0.5	-0.2	0.8
Prospective memory result	0.3	0.4	1.6	-0.8	-0.1	0.5	0.4	0.6	1.2	0.5	-0.8	0.3
Lung cancer (father)	0.6	0.7	2.5	-1.6	1.2	0.3	-0.7	-0.8	0.9	0.1	0.6	-0.5
Illnesses of mother	1.3	1.6	2.2	1.5	0.3	1.4	1.4	1.3	1.2	1.3	-1.3	1.3
Forced expiratory volume in 1-second (FEV1), Best measure	1.6	5.0	11.7	0.3	0.8	3.4	2.7	3.1	2.5	1.4	-0.3	2.7
Pulse wave Arterial Stiffness index	2.2	2.6	4.8	1.2	-1.2	1.3	2.2	2.2	1.7	1.1	-1.2	2.0
Impedance of arm (left)	0.2	0.8	3.4	-0.9	-0.9	1.0	-0.3	-0.6	-0.6	-0.1	-1.9	-0.3
Arm fat mass (right)	1.4	5.6	14.3	0.1	-0.4	2.7	2.8	3.8	2.0	-0.2	2.7	3.2
Trunk predicted mass	0.4	2.0	6.7	0.9	2.6	2.0	0.1	1.4	-0.1	-1.7	1.2	0.6
Standing height	0.3	3.0	8.0	0.6	2.1	2.4	-1.6	-0.2	-2.1	-2.8	-0.7	-1.0
Length of working week for main job	0.6	0.6	1.9	-0.1	0.1	-1.3	-0.2	-0.9	-1.4	0.5	0.8	-0.4
Exposure to tobacco smoke at home	3.9	4.4	11.0	-1.7	0.2	-1.6	-3.3	-2.7	-1.9	-2.1	0.4	-2.8
Breastfed as a baby	0.8	1.0	3.2	1.0	0.8	0.9	0.6	0.2	1.0	1.4	-1.8	0.1
Tense / ‘highly strung’	0.8	1.3	3.1	0.7	1.0	-0.0	-1.7	-1.1	-0.7	-1.4	1.8	-0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.7	2.3	-1.0	1.5	0.0	-0.7	-0.6	-0.9	-0.8	0.2	-0.6
Hair/balding pattern: Pattern 4	0.2	0.5	1.5	-0.0	-0.0	-0.6	-0.9	-0.6	-1.1	-1.2	0.4	-0.4
Birth weight of first child	0.3	0.6	2.0	-0.9	0.6	1.3	0.1	-0.2	-0.3	0.2	1.4	-0.1
Peak expiratory flow (PEF)	1.1	2.5	5.2	0.8	0.7	1.6	2.2	2.3	1.7	1.1	-1.1	1.9
Pulse wave reflection index	0.7	0.8	1.6	0.8	-1.0	0.8	0.7	1.1	-0.4	-0.8	1.2	1.1
Ever highly irritable/argumentative for 2 days	0.7	0.8	2.5	-0.3	1.3	-0.2	0.5	0.2	1.5	1.6	0.7	0.3
Loud music exposure frequency	2.1	2.3	5.7	1.2	0.6	0.6	1.6	2.0	2.4	0.8	0.4	2.4
Qualifications: O levels/GCSEs or equivalent	0.5	0.9	5.5	0.4	-0.7	0.4	0.6	0.3	0.5	0.8	-2.4	0.1
Mouth/teeth dental problems: Bleeding gums	1.2	1.6	5.6	-0.4	-1.3	2.4	-0.2	0.4	-2.0	-1.2	-0.7	-0.5
Blood clot in the leg (DVT)	0.7	0.9	4.9	0.8	-0.5	-0.6	-1.0	-0.2	-0.8	-2.2	-0.6	-0.0
Medication: Paracetamol	0.4	0.7	3.1	-1.8	-0.9	-0.8	0.2	0.0	0.3	1.0	-0.9	-0.0
Headache pain in last month	0.5	0.9	3.7	-0.2	-1.1	-0.6	-0.2	-0.6	0.3	1.3	-1.9	-0.6
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.4	-0.6	0.7	0.6	0.6	0.7	0.7	-0.2	-1.2	0.8
Glaucoma (self-reported)	0.6	0.7	2.0	0.1	0.1	1.4	-0.4	0.1	-1.3	-1.2	-1.1	-0.4
Gout (self-reported)	0.5	0.7	2.4	0.8	-0.0	-1.6	-0.7	-0.5	-0.9	-1.1	-0.6	-0.4
Hypothyroidism/myxoedema (self-reported)	0.1	0.3	0.8	0.9	0.2	0.5	-0.0	0.4	0.3	-0.9	0.1	0.6
Medication: Amlodipine	0.7	0.9	2.5	-0.2	-1.1	-0.1	-1.1	-0.8	-1.6	-0.8	-0.2	-1.4
Medication: Ventolin 100micrograms inhaler	1.4	1.8	3.4	-1.3	-0.1	1.5	-1.6	-1.4	-1.6	-0.9	0.9	-1.9
Birth weight	0.4	0.9	2.8	0.9	-0.6	0.4	-0.9	-0.5	-1.5	-1.7	0.1	-0.9
Chronic bronchitis/emphysema (mother)	1.2	1.4	4.9	0.0	-0.5	-0.4	-1.8	-1.8	-0.7	-0.3	0.1	-2.2
High blood pressure (siblings)	2.3	3.3	8.0	-0.9	-0.9	-2.2	-2.3	-2.1	-1.1	-1.0	2.8	-1.8
Forced vital capacity (FVC), Best measure	0.8	2.8	10.5	0.5	1.2	3.2	1.6	2.2	1.3	0.2	-0.2	1.9
Body fat percentage	1.2	4.9	11.4	-0.5	-1.1	2.3	2.7	3.4	1.9	0.1	2.3	3.0
Leg fat percentage (right)	1.2	4.2	10.4	-0.3	-0.9	1.6	2.4	2.8	2.0	0.6	3.2	2.6
Arm fat-free mass (right)	0.3	1.5	3.1	0.4	1.7	1.8	0.5	1.8	-0.4	-1.5	1.0	0.8
Exposure to tobacco smoke outside home	0.2	0.3	1.2	0.4	-1.1	0.1	0.4	0.3	0.3	0.9	-0.3	0.1
Comparative body size at age 10	2.3	6.3	14.6	-1.8	-0.6	-1.0	-3.6	-3.1	-2.9	-2.3	-1.1	-3.8
Number of full brothers	0.5	0.6	2.3	0.7	-0.6	-1.2	-0.1	-0.5	0.4	0.7	1.5	-0.4
Worry too long after embarrassment	0.4	0.6	2.6	-0.1	-1.6	-0.6	-0.6	-0.7	-0.5	0.4	0.0	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	5.1	-0.0	-0.6	2.3	0.3	0.5	0.3	-0.1	0.2	-0.0
Wheeze or whistling in the chest in last year	1.2	2.2	7.2	-1.0	-0.7	1.1	1.4	1.6	1.2	0.4	2.7	1.9
Number of children fathered	1.3	1.5	3.5	-0.0	1.4	0.2	-1.4	-1.4	-1.2	-0.6	-1.9	-1.6
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.2	4.4	-0.8	-0.1	0.3	-0.7	-0.3	-2.0	-2.1	0.7	-0.3
Age at first live birth	0.8	1.4	5.9	2.4	0.2	0.4	0.9	1.0	1.1	0.7	1.3	1.0
Pulse wave peak to peak time	2.4	2.8	5.5	-1.1	1.4	-1.2	-2.3	-2.3	-1.7	-1.1	1.1	-2.2
Health satisfaction	0.9	1.2	3.6	-1.2	-1.5	1.9	0.9	0.9	0.5	0.9	-0.1	0.7
Shortness of breath walking on level ground	0.2	0.2	1.0	-1.0	-0.2	0.0	-0.5	-0.1	-0.1	-0.7	-0.3	-0.3
Qualifications: College or University degree	1.3	4.1	10.6	3.3	-1.6	1.2	2.3	1.7	1.2	2.1	-2.1	1.7
Eye problems/disorders: None of the above	1.4	1.6	5.5	0.4	-1.4	-0.6	1.3	0.6	1.1	2.4	-1.7	0.4
Mouth/teeth dental problems: Loose teeth	0.7	0.9	1.4	-1.1	-0.7	-1.0	-1.2	-1.1	-0.9	-1.0	0.9	-0.4
Emphysema/chronic bronchitis	0.5	0.5	1.1	1.1	-0.9	0.8	-0.5	-0.3	-0.4	-0.4	0.9	-0.7
Medication for pain relief, constipation, heartburn	0.2	0.4	1.8	0.6	0.3	1.3	0.5	0.6	0.3	-0.8	-0.1	0.6
Neck or shoulder pain in last month	0.8	1.1	2.0	-0.7	0.7	1.0	1.3	1.2	1.1	1.4	0.4	1.3
Medication: Blood pressure	0.4	0.6	3.9	-0.7	-2.0	-0.5	-0.2	-0.2	-0.4	0.2	0.5	-0.8
Angina (self-reported)	3.1	4.1	9.6	-0.3	0.4	-2.0	-2.8	-1.8	-2.7	-3.1	-0.1	-2.0
Migraine (self-reported)	0.1	0.2	0.6	-0.2	0.0	0.4	-0.5	-0.1	-0.5	-0.8	-0.4	0.1
Medication: Ibuprofen	0.5	0.6	1.6	-1.3	-1.2	0.5	-0.3	-0.6	-0.2	0.7	0.3	-0.8
Medication: Allopurinol	0.6	0.8	2.5	0.3	-0.7	-1.6	-1.0	-1.0	-0.8	-0.8	-0.8	-0.7
Medication: Omeprazole	0.6	0.7	1.3	-0.8	-0.5	-0.9	-0.9	-0.9	-0.6	-0.5	-1.1	-1.0
Medication: Seretide 50 evohaler	2.1	2.5	5.3	0.2	2.0	0.0	-2.3	-2.2	-1.4	-1.1	1.1	-2.0
Mean time to correctly identify matches	0.2	0.3	1.1	0.2	-0.3	-0.5	-0.5	-0.2	0.7	-0.8	1.1	0.3
Heart disease (mother)	0.6	0.8	2.5	-0.6	-0.1	-1.6	-0.9	-0.9	-0.9	-0.6	0.7	-0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	2.0	-1.1	0.3	-1.0	-1.0	-1.2	-0.4	0.1	-0.2	-1.4
Whole body fat mass	1.1	4.5	11.5	-0.2	-0.5	2.5	2.5	3.4	1.5	-0.4	2.5	2.7
Leg fat mass (right)	1.2	4.7	10.7	0.1	-0.5	2.0	2.4	3.3	1.8	-0.3	3.3	2.8
Arm predicted mass (right)	0.3	1.7	3.6	0.4	1.8	1.9	0.6	1.9	-0.2	-1.6	0.9	0.9
Pulse rate, automated reading	3.2	10.4	21.4	0.8	-0.1	2.4	4.2	4.2	4.6	2.8	2.2	4.1
Alcohol intake frequency.	0.7	1.6	5.2	-0.7	-1.7	-0.0	-0.4	0.3	-2.3	-2.3	0.7	0.2
Comparative height size at age 10	0.3	1.5	3.1	-0.9	1.4	0.3	-1.8	-1.1	-1.3	-1.6	-1.0	-1.4
Number of full sisters	1.0	1.2	2.5	0.5	-0.7	1.4	1.1	1.3	1.6	0.2	0.2	1.5
Suffer from ‘nerves’	0.2	0.4	1.2	-0.6	0.7	0.5	-0.2	0.2	-0.3	-0.8	1.1	-0.1
Overall health rating	0.9	1.8	4.9	-1.2	-1.5	2.2	0.8	1.2	-0.1	-0.2	2.2	1.0
Chest pain or discomfort	0.1	0.2	0.7	-0.3	-0.8	0.7	0.2	0.1	0.2	0.5	-0.1	0.0
Had major operations	0.6	0.7	2.8	1.7	-0.9	0.1	0.3	0.5	-0.5	-0.3	1.1	0.7
Age at last live birth	1.0	1.5	3.9	2.0	0.8	0.7	1.0	1.1	0.8	0.6	2.0	1.2
Family relationship satisfaction	0.3	0.4	1.3	-0.1	-1.0	-0.0	0.2	-0.1	1.1	1.0	0.6	0.1
Leg pain on walking	1.3	1.6	3.7	-0.2	-1.5	1.7	1.6	1.9	0.5	0.1	-1.0	1.3
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	2.9	-1.2	-0.6	-0.9	-1.1	-1.7	0.4	1.2	-0.1	-1.6
Commuting to job workplace: Car/motor vehicle	0.4	0.5	1.2	-0.7	-1.1	0.3	0.5	0.9	0.6	0.3	0.2	0.8
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	3.7	0.6	0.7	0.6	-0.6	-0.5	-1.0	-0.4	-1.9	-0.8
Medication: Aspirin	0.4	0.5	1.5	1.2	0.5	-1.1	-0.4	-0.4	0.0	-0.0	1.1	-0.3
Supplements: Vitamin C	0.4	0.5	1.1	-0.7	-0.7	-0.4	-0.5	-0.9	0.4	1.0	-0.1	-0.9
Knee pain experienced in last month	1.1	1.7	5.6	-0.5	-2.4	1.8	1.2	1.2	0.9	0.9	0.4	1.2
Hypertension (Self-reported)	0.4	1.1	5.6	-0.9	-2.4	-0.7	0.2	0.2	0.4	0.7	1.6	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	1.0	3.1	1.8	-1.2	0.8	0.7	0.6	-0.5	-0.1	-1.5	0.5
Illnesses of father: Heart disease	0.5	0.7	3.7	0.4	-0.8	-0.6	-0.1	-0.1	-1.2	-0.4	1.9	0.1
Illnesses of siblings: Diabetes	0.4	0.5	2.4	0.2	-0.1	0.7	0.1	0.4	0.7	-0.2	1.6	0.6
Smoking status: Previous	0.6	0.8	1.7	-0.7	1.1	0.9	-1.3	-0.7	-0.5	-1.2	0.6	-0.9
Forced expiratory volume in 1-second (FEV1), predicted	1.2	2.4	4.8	-0.9	1.9	1.5	-1.7	-0.7	-2.0	-2.2	-0.8	-1.4
Whole body fat-free mass	0.4	2.5	6.1	1.1	2.1	2.5	0.9	2.2	0.3	-1.4	1.3	1.3
Leg fat-free mass (right)	0.5	2.9	7.7	0.9	1.2	2.5	1.5	2.8	0.4	-1.3	1.4	1.9
Arm fat percentage (left)	1.5	6.0	14.4	-0.6	-1.2	2.8	3.2	3.8	2.0	0.2	2.3	3.3
Average weekly red wine intake	1.6	2.4	14.0	0.1	-0.2	-0.3	1.1	-0.3	1.7	3.7	-1.7	-0.0
Handedness (chirality/laterality): Left-handed	1.4	1.7	3.1	-1.2	0.9	-1.8	-1.5	-1.4	-1.7	-0.8	0.5	-1.6
Mood swings	0.4	0.7	3.5	1.0	0.0	1.9	-0.3	0.6	-0.1	-1.4	0.1	0.1
Loneliness, isolation	0.6	0.9	5.8	-0.2	-1.0	2.4	0.1	0.1	-0.7	-0.1	0.7	-0.1
Long-standing illness, disability or infirmity	1.4	2.1	11.8	-3.4	-0.2	-0.9	-1.1	-1.5	-0.2	0.7	0.8	-1.3
Ever had bowel cancer screening	0.5	0.6	2.7	-1.1	-1.6	0.5	0.4	0.1	-0.5	-0.0	0.8	0.1
Diabetes diagnosed by doctor	0.3	0.4	1.4	0.1	0.2	0.5	0.1	0.4	-0.3	-1.1	1.2	0.8
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	4.0	0.7	0.9	1.3	0.4	0.4	0.6	1.3	2.0	-0.0
Friendships satisfaction	2.1	2.7	9.7	-0.4	-1.1	1.0	1.8	0.9	2.4	3.1	-0.7	1.2
Qualifications: nursing, teaching	3.1	4.8	9.4	1.5	0.2	0.8	3.1	2.9	2.6	1.8	-1.7	3.0
Commuting to job workplace: Walk	1.0	1.1	3.3	0.1	-1.8	0.8	-0.7	-0.5	-1.3	-1.6	-0.7	-0.5
Eye problems/disorders: Cataract	2.5	2.9	6.7	-0.6	1.7	0.6	-2.6	-2.0	-1.6	-2.4	1.0	-1.5
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	4.2	1.4	1.1	-0.9	-0.9	-0.4	0.1	-1.0	2.0	-0.3
Medication for cholesterol	0.8	1.2	5.1	-0.8	2.3	-0.2	-0.6	-1.3	-0.4	0.8	-1.0	-1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	4.4	0.7	-0.9	-2.1	0.2	0.3	0.2	0.5	1.3	0.4
Back pain experienced in last month	0.2	0.3	0.8	-0.4	-0.7	0.6	0.9	0.8	-0.3	0.6	0.1	0.5
Mineral and other dietary supplements	1.0	1.3	3.6	0.2	1.2	1.2	0.6	1.8	0.3	-1.9	-0.6	1.2
Breast cancer (self-reported)	1.1	1.3	3.2	1.1	1.1	0.7	0.5	1.4	0.4	-1.8	0.1	1.7
Asthma (self-reported)	0.4	0.9	4.3	-0.2	-0.3	2.1	0.6	0.7	0.2	-0.2	1.3	0.7
Osteoporosis (self-reported)	0.6	0.8	3.8	-0.8	-0.2	1.5	0.3	0.4	0.1	0.1	-2.0	0.2
Osteoarthritis (self-reported)	1.1	1.4	4.5	-1.8	-0.3	-1.1	-0.9	-1.0	0.6	0.7	2.1	-0.8
Medication: Aspirin	0.4	0.5	1.1	0.8	0.4	-0.9	-0.7	-0.6	-0.4	-0.5	1.0	-0.6
Medication: Gliclazide	0.2	0.3	1.4	-0.2	-0.3	0.2	0.5	0.5	-0.2	-0.0	-1.2	0.3
Illnesses of father: None of the above (group 1)	0.6	0.8	1.4	0.9	1.2	1.0	0.7	0.8	0.8	-0.4	-1.0	0.9
Smoking status: Current	0.4	0.7	3.1	-0.7	1.8	0.1	-0.6	-0.5	-0.5	-0.5	1.0	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.5	5.4	9.1	-1.3	-2.0	2.6	2.9	2.6	3.0	2.4	-0.3	2.5
Whole body water mass	0.4	2.6	6.2	1.0	2.0	2.5	0.8	2.2	0.1	-1.6	1.4	1.3
Leg predicted mass (right)	0.5	2.9	7.8	0.8	1.1	2.5	1.5	2.8	0.3	-1.4	1.4	1.9
Arm fat mass (left)	1.3	5.5	14.8	-0.2	-0.7	2.7	2.8	3.8	1.4	-0.5	2.6	3.2
Number of self-reported non-cancer illnesses	0.4	0.7	3.1	-0.7	-1.5	0.2	0.0	0.2	0.4	0.0	1.8	0.4
Average weekly champagne plus white wine intake	0.6	0.8	2.1	0.4	-1.4	-0.6	0.6	0.1	0.8	1.1	-1.5	0.2
Miserableness	0.6	1.1	4.8	1.1	2.2	1.0	0.0	0.7	0.9	-0.9	0.4	0.6
Guilty feelings	0.2	0.3	1.6	0.1	-0.4	-0.2	-0.1	-0.5	0.0	1.0	1.3	-0.4
Wears glasses or contact lenses	0.7	0.8	2.0	1.2	0.3	0.0	-1.3	-1.4	-0.4	-0.3	-0.4	-1.3
Ever taken oral contraceptive pill	1.0	1.1	5.8	-0.1	0.9	-0.5	0.9	0.4	0.7	1.4	-2.4	0.1
Hearing aid user	0.1	0.2	0.7	-0.1	0.4	0.1	-0.3	-0.2	-0.6	-0.9	-0.1	-0.2
Mother’s age at death	1.5	1.9	5.5	0.5	-0.1	-2.3	-1.8	-1.9	-0.4	-0.4	1.2	-1.6
Financial situation satisfaction	0.3	0.4	1.4	-1.0	-0.8	0.2	0.1	0.2	-0.2	0.2	-1.2	-0.2
Tinnitus: Yes, now most or all of the time	0.3	0.4	0.9	0.2	-0.5	0.5	0.6	0.8	0.6	0.2	0.9	0.9
Commuting to job workplace: Public transport	0.7	0.9	3.6	0.9	0.3	-0.5	-0.3	-1.0	-0.2	0.9	-1.9	-1.1
Eye problems/disorders: Glaucoma	0.5	0.7	2.1	1.4	0.7	0.8	0.1	0.3	-0.5	-0.6	-1.5	0.0
Medication: Blood pressure	0.4	0.7	2.2	-0.1	-0.4	-1.1	-0.6	-0.1	-0.7	-1.4	1.5	-0.1
Pain type(s) experienced in last month: Hip pain	1.9	2.4	12.3	-1.0	-3.5	1.4	1.4	1.2	0.5	0.7	-1.3	0.6
Supplements: Fish oil (including cod liver oil)	0.4	0.6	1.7	0.4	-0.7	-0.4	-0.0	-0.8	-1.1	1.3	0.6	-0.6
High cholesterol (Self-reported)	0.7	1.2	2.1	0.2	-1.4	-1.1	-1.0	-1.2	-1.4	-0.4	1.4	-1.0
Medication: Bendroflumethiazide	0.5	0.8	2.7	-1.0	-1.6	0.2	0.7	1.0	1.0	0.0	-0.5	0.9
Medication: Paracetamol	0.5	0.8	2.9	-1.4	-1.7	-0.9	-0.1	-0.3	-0.4	0.7	-0.6	-0.4
Medication: Lisinopril	0.6	0.8	2.5	-0.5	-1.5	-0.0	-0.3	0.1	-1.6	-1.0	0.9	-0.3
Medication: Atorvastatin	3.1	3.8	9.5	-0.9	0.8	-3.1	-2.5	-2.6	-1.8	-1.2	1.3	-2.1
Illnesses of father: High blood pressure	1.4	1.7	13.5	-0.0	-3.7	0.8	0.6	0.5	-0.6	0.2	0.7	-0.0
Alcohol drinker status: Never	0.2	0.2	0.5	0.5	-0.6	-0.0	0.2	0.2	-0.5	-0.5	0.3	0.7
Ever smoked	0.6	1.0	4.9	-0.2	2.2	0.1	-1.0	-0.8	-0.1	-0.6	1.2	-0.9
Basal metabolic rate	0.5	2.9	6.9	0.9	1.6	2.5	1.2	2.6	0.5	-1.4	1.7	1.7
Leg fat percentage (left)	1.0	3.7	8.2	-0.6	-1.1	1.3	2.3	2.7	1.7	0.3	2.9	2.5
Arm fat-free mass (left)	0.3	1.7	3.7	0.8	1.5	1.7	0.7	1.9	0.3	-1.3	1.6	1.1
Number of operations (self-reported)	0.5	0.8	2.9	1.0	-1.2	0.7	0.3	0.4	-0.2	-0.3	1.7	0.7
Average weekly beer plus cider intake	1.7	2.5	6.8	1.1	1.6	0.8	1.5	2.1	2.6	0.3	-0.2	2.1
Irritability	0.6	1.1	4.2	1.7	0.0	0.5	-0.2	0.4	0.5	-1.1	2.1	0.6
Risk taking	3.5	5.1	16.7	1.2	-1.1	-0.6	2.6	1.3	2.9	4.1	2.3	1.9
Ever had prostate specific antigen (PSA) test	0.5	0.6	3.2	-1.2	-1.8	0.2	0.5	0.2	0.2	0.4	-0.2	0.2
Fractured/broken bones in last 5 years	0.7	0.9	3.8	0.8	0.9	1.9	0.9	1.0	-0.4	0.6	-0.1	0.7
Age started oral contraceptive pill	0.4	0.4	1.1	-0.1	-1.0	0.2	0.7	1.0	-0.2	-0.7	-0.2	1.1
Diastolic blood pressure, automated reading	0.6	1.7	3.4	-0.3	-1.2	-0.1	1.8	1.7	1.6	1.6	1.2	1.1
Ever depressed for a whole week	1.6	2.0	5.0	-0.8	0.8	-1.4	-2.2	-2.1	-0.4	-0.1	0.0	-2.2
Unable to work because of sickness or disability	1.3	1.7	4.9	-1.6	-0.3	-1.2	-1.4	-1.0	-1.0	-1.1	2.2	-1.1
Commuting to job workplace: Cycle	0.6	0.7	4.6	-0.5	2.1	1.0	0.1	0.2	-0.3	-0.4	0.5	0.2
Myopia	0.2	0.2	1.3	-1.1	-0.5	-0.2	-0.0	-0.1	0.7	0.1	-0.4	-0.2
Vascular/heart problems diagnosed by doctor	0.4	1.0	2.8	1.1	1.6	1.1	0.2	0.3	0.2	-0.5	-1.7	0.7
Cholesterol lowering medication	0.9	1.3	4.6	1.2	-2.1	-0.4	0.2	0.5	0.2	-0.6	2.1	0.8
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.5	-1.1	-0.7	-0.1	-0.1	-0.1	-0.4	-0.1	-1.2	-0.3
Pain experienced in last month	1.3	2.2	5.1	-0.4	1.5	-2.3	-1.8	-1.9	-1.2	-1.5	0.5	-1.4
Supplements: Calcium	0.6	0.7	2.3	0.3	-1.5	0.3	-0.3	-0.8	0.3	1.4	-0.9	-0.4
Basal cell carcinoma (self-reported)	0.4	0.5	1.7	-0.2	-1.3	-0.0	-0.4	-0.3	-1.3	-0.6	0.3	-0.4
Heart attack/myocardial infarction (self-reported)	3.3	4.2	7.8	-0.4	1.1	-2.2	-2.6	-2.5	-2.8	-1.8	0.3	-2.8
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	4.2	0.8	-0.6	-1.1	-1.1	-0.5	-0.8	-2.1	-0.3	-0.1
Heart disease (siblings)	1.9	2.4	3.7	1.3	-1.9	1.6	1.9	1.7	0.8	1.5	1.1	1.6
Alcohol drinker status: Previous	1.8	2.0	6.6	-0.2	1.4	0.2	-0.9	-0.2	-2.6	-2.5	1.5	-0.2
Pack years of smoking	0.6	0.8	3.8	1.9	-1.1	0.2	0.7	0.7	0.9	0.5	-0.2	0.6
Impedance of whole body	0.1	0.6	3.5	-0.9	-0.6	0.2	-0.5	-0.8	-0.2	0.0	-1.9	-0.3
Leg fat mass (left)	1.1	4.3	10.9	0.1	-0.5	1.9	2.4	3.3	1.6	-0.4	2.9	2.7
Arm predicted mass (left)	0.4	1.8	3.2	1.1	1.7	1.8	0.6	1.8	0.3	-1.3	1.7	1.0