Hub : Genes

TRIM24

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.2550	0.0460	2.9e-10	0.075	NA	0.178	NA	0.171	9.3e-07	NA	1.9e-14	NA	6.1e-14
2	GTEx	Adipose Visceral Omentum	0.2940	0.0760	1.4e-04	-0.005	NA	0.038	NA	0.004	9.7e-01	NA	4.8e-03	NA	1.8e-01
3	GTEx	Breast Mammary Tissue (Female)	0.2116	0.1076	3.6e-02	0.025	NA	0.048	NA	0.031	6.2e-02	NA	1.5e-02	NA	4.2e-02
4	GTEx	Testis	0.3830	0.0910	5.1e-05	0.137	NA	0.076	NA	0.164	1.2e-06	NA	2.9e-04	NA	9.6e-08
5	METSIM	Adipose	0.1688	0.0351	1.3e-07	0.018	0.043	0.078	0.054	0.059	8.4e-04	3.9e-07	9.8e-12	1.5e-08	3.0e-09
6	ROSMAP	Brain Pre-frontal Cortex	0.0858	0.0262	2.9e-04	0.014	0.018	0.017	0.019	0.021	4.8e-03	2.0e-03	2.2e-03	1.6e-03	8.3e-04
7	YFS	Blood	0.1358	0.0225	0.0e+00	0.072	0.077	0.099	0.100	0.098	2.2e-22	5.8e-24	9.1e-31	6.7e-31	2.3e-30
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.0847	0.0349	1.4e-03	0.034	0.046	0.030	NA	0.026	8.5e-05	6.0e-06	2.3e-04	NA	5.5e-04
9	TCGA	Thyroid Carcinoma	0.0810	0.0330	2.0e-03	0.014	0.032	0.034	NA	0.036	1.3e-02	4.0e-04	2.6e-04	NA	1.9e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.6	0.9	2.9	-0.4	-0.7	-1.7	0.7	-1.3	1.1	-0.1	1.2	-0.5
Bipolar Disorder or Schizophrenia	0.6	1.5	3.6	-0.1	0.2	-1.9	1.6	-1.4	1.5	-0.1	1.1	-1.5
Depressed Affect (Nagel 2018)	0.5	1.1	5.4	-0.6	-0.2	-0.7	-1.4	-0.5	2.3	0.6	-0.5	-0.8
Depression (Nagel 2018)	0.5	0.7	2.5	0.8	1.6	0.4	-0.5	0.3	0.4	-0.8	0.2	-1.3
Intelligence (Savage-Jansen 2018)	0.2	0.6	2.0	-0.3	-0.6	-0.1	-0.2	-0.6	1.4	0.8	0.9	-0.8
Neuroticism (Nagel 2018)	0.6	1.4	3.6	-1.1	-1.6	-0.7	-1.1	-1.0	1.9	0.7	-0.8	-1.2
Schizophrenia (2018)	0.5	1.1	2.5	0.2	1.0	-1.5	1.5	-0.7	1.1	-0.0	0.6	-1.6
Schizophrenia vs Biploar Disorder	1.6	2.1	4.5	-1.3	-0.4	-1.6	1.7	-0.5	1.9	-0.3	-2.1	-1.7
Worry (Nagel 2018)	0.4	0.8	1.8	-0.9	-1.3	1.0	-1.2	-0.4	-0.6	-0.0	-0.0	-1.3
Alzheimer’s Disease (in mother)	1.5	1.7	6.3	1.0	-0.2	2.5	0.4	0.8	-1.5	-2.1	0.7	-0.7
Alzheimer’s Disease (in father)	0.4	0.4	1.2	0.8	-0.4	-0.1	0.9	0.1	-0.4	-1.1	-0.8	-0.6
Alzheimer’s Disease (including proxy)	1.4	2.1	11.3	0.7	-0.8	1.4	0.5	-0.5	-1.7	-3.4	0.6	-0.8
Crohns Disease (2017)	0.9	1.9	7.5	0.2	-0.0	-1.1	-2.7	-0.5	-0.6	-0.7	2.6	0.5
Irritable Bowel Disease (IBD)	0.7	1.6	5.8	-0.6	-0.4	-1.6	-1.2	-0.9	-0.7	-1.7	2.4	-0.2
Ulcerative Colitis (UC)	0.6	1.1	4.7	-0.8	-0.0	-1.1	0.8	-0.9	-0.5	-2.2	1.1	-0.7
Major Depression (MDD)	0.5	0.6	3.5	0.1	0.2	-0.8	-0.2	0.1	1.9	-0.5	0.3	-0.9
Reaction Time	0.5	0.9	2.5	-0.4	-0.6	-0.6	1.5	1.6	0.6	1.4	0.4	-0.5
Verbal and Numeric Reasoning (VNR)	0.4	0.9	3.7	-0.5	0.8	0.1	-0.5	-0.0	1.9	1.5	0.8	0.8
Breast Cancer	0.2	0.5	1.8	-1.2	-0.3	-0.0	-0.7	1.3	-0.4	0.1	0.3	0.6
Ovarian Cancer	0.6	0.8	2.1	0.7	0.5	0.4	0.9	1.3	0.2	1.3	-0.3	-1.4
Prostate Cancer	0.6	0.8	2.1	1.0	1.5	1.3	0.1	1.0	0.4	0.8	-0.2	0.9
Age at First Birth	0.6	0.9	4.9	0.6	-1.1	-0.2	0.3	0.5	0.8	-0.4	-2.2	-0.8
Bipolar Disorder (2011)	1.1	1.1	7.7	2.8	0.0	0.0	0.4	0.0	0.7	-0.6	0.6	-0.8
Body Mass Index (BMI) (2010)	0.6	0.8	4.7	-0.3	0.3	0.5	-2.2	0.2	-1.0	-0.4	1.1	-0.0
Coronary Artery Disease (CAD)	2.3	2.7	7.0	2.6	2.0	2.5	0.7	0.7	-1.8	-0.1	-1.6	0.6
Crohns Disease (2012)	0.8	1.2	4.6	1.5	0.7	0.1	-2.1	-0.4	-0.6	-1.4	0.7	0.9
Mean Putamen Volume	0.7	0.8	1.9	-1.3	-1.4	0.6	1.0	-1.0	-0.0	-0.8	0.6	0.5
Fasting Glucose	1.0	1.2	4.1	-2.0	-0.7	0.0	-1.2	-0.3	-0.7	0.7	1.0	1.5
HbA1C	1.1	1.2	4.1	-1.7	-0.7	-0.4	-1.3	-2.0	1.2	-0.1	-0.3	0.3
HDL Cholesterol	0.6	1.1	2.8	1.5	1.1	-0.3	-0.8	1.7	-0.7	-0.6	-1.2	-0.5
LDL Cholesterol	0.4	0.6	4.0	0.1	0.3	0.1	0.8	-2.0	0.1	0.4	-0.2	0.7
Lupus	0.8	1.2	2.6	-1.1	-1.4	0.7	-0.8	0.9	-1.6	-0.3	-1.5	-0.7
Neuroticism (2016)	0.8	1.2	3.9	1.0	1.2	0.3	-2.0	-0.2	-0.9	-1.4	1.1	0.4
Primary Biliary Cirrhosis	1.6	2.2	6.1	-2.5	-0.8	-0.0	-2.0	-1.5	-1.1	0.1	1.4	1.9
Rheumatoid Arthritis	1.8	2.4	10.1	0.4	1.9	-0.5	-2.0	-1.4	-0.1	0.0	3.2	1.4
Schizophrenia (2014)	0.5	1.2	3.6	0.1	0.6	-0.6	1.7	-1.1	1.2	0.3	1.0	-1.9
Triglycerides	0.8	1.3	3.1	-0.4	-1.5	-0.4	0.9	-1.8	1.2	1.3	1.3	0.5
Type 2 Diabetes (T2D) (2012)	0.7	0.9	2.4	-1.6	-0.8	-1.5	0.6	-0.6	0.1	0.1	0.7	1.1
Ulcerative Colitis	0.4	0.6	2.0	0.1	-0.4	-0.7	0.5	0.2	-1.4	-1.1	0.6	1.0
Blood Eosinophil Count	0.7	5.4	14.5	-3.8	0.0	-2.5	0.7	1.3	3.7	2.3	-1.6	-2.0
Blood Platelet Count	0.2	2.4	8.1	0.5	1.2	2.2	0.8	2.9	-1.5	-0.0	-1.7	1.1
Blood Red Count	0.2	1.7	5.6	-2.4	-0.5	0.2	2.4	-1.4	-0.8	-0.6	1.0	0.4
Blood White Count	0.3	2.2	7.2	-1.2	1.0	0.2	-0.5	1.4	1.2	2.7	2.2	1.4
Heel T-Score	0.3	2.7	8.0	0.6	-2.5	1.0	2.8	0.3	-1.1	-1.6	-2.1	-0.6
BMI	0.3	1.7	4.3	0.5	1.1	-0.1	-1.7	-1.9	1.5	0.4	2.1	0.9
Height	0.1	1.9	7.5	-2.7	-0.5	-0.2	-1.5	-2.0	-0.1	-0.8	1.2	0.8
Waist Hip Ratio (WHR)	2.1	9.4	21.9	-3.8	-4.2	-2.7	1.4	-4.7	1.8	-2.4	-1.7	-3.1
Systolic Blood Pressure	0.2	1.0	2.3	1.0	1.4	0.5	0.2	0.9	-1.4	-1.5	0.1	-0.1
Smoking Status	0.5	1.2	4.7	-0.7	0.6	-0.7	0.6	-2.2	1.5	-1.2	0.1	-0.5
Allergy or Eczema	0.3	0.9	5.4	-0.4	0.1	-0.2	-0.4	1.4	0.3	2.3	-0.4	-0.4
Cardiovascular Disease	0.4	1.2	7.5	0.7	0.4	0.4	-0.0	-2.7	0.2	-0.9	0.5	1.1
Hypothyroidism (self reported)	0.6	1.4	5.1	-2.3	-0.8	-0.8	-1.2	-1.2	-0.3	0.9	1.4	0.3
Respiratory disease	0.3	0.6	1.3	0.5	0.1	0.6	0.9	0.8	0.8	1.1	-0.9	-0.6
Type 2 Diabetes (T2D) (2018)	2.1	4.0	13.0	-1.6	-1.9	0.1	3.6	-2.7	-0.4	-1.6	-2.5	0.7
Lung FEV1/FVC ratio	0.3	1.6	3.4	-1.6	-1.4	-0.2	1.2	-1.8	-0.9	-0.5	1.0	-1.8
Lung FVC	1.5	7.4	26.1	1.4	-1.0	-0.4	5.1	2.6	1.8	0.9	-4.3	-2.9
Neuroticism	0.5	1.3	3.1	0.2	-0.8	-0.3	-1.8	-1.4	1.6	-0.5	-0.7	-1.5
Chronotype (morning person)	0.4	0.8	2.5	-0.6	0.1	-1.6	-1.4	-1.2	0.2	-0.5	0.3	-0.9
Hair Pigment	0.0	0.6	2.2	0.5	0.6	0.5	0.8	0.3	0.3	-1.5	-1.2	-0.5
Tanning	0.1	1.0	3.8	0.9	0.4	0.6	0.3	1.9	0.2	1.9	0.8	0.3
Hand grip strength (left)	0.8	2.1	5.8	0.1	-1.8	-0.7	2.4	-0.1	2.4	1.4	0.4	-1.2
Number of treatments/medications taken	0.7	1.2	6.8	-0.3	0.6	1.0	0.7	-2.6	0.5	-0.9	0.3	1.0
Average weekly spirits intake	1.0	1.2	4.2	-0.8	1.1	0.6	-1.2	-2.0	-0.5	-1.6	-0.4	-0.5
Sensitivity / hurt feelings	0.5	0.9	4.2	-1.0	-0.9	-2.0	-0.6	-0.0	1.3	-0.0	0.1	-0.2
Frequency of depressed mood in last 2 weeks	0.4	0.6	2.8	0.8	1.7	0.4	-0.4	0.9	0.2	-0.1	0.5	-0.7
Hearing difficulty/problems: Yes	0.4	0.7	2.3	0.8	0.7	1.1	-1.5	0.6	-0.1	0.1	-0.2	-0.9
Relative age of first facial hair	0.2	0.5	1.6	0.2	0.2	1.2	-1.3	0.4	-0.1	0.5	0.7	-0.1
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	3.6	-1.9	0.6	0.1	-0.9	-0.6	0.1	-0.0	1.7	1.8
Ever used hormone-replacement therapy (HRT)	1.5	1.9	5.6	-0.8	0.6	2.4	-1.6	-0.9	-2.0	-1.0	1.2	0.5
Ever had hysterectomy (womb removed)	0.7	0.8	2.5	0.7	1.6	0.5	1.0	-0.1	-0.4	-1.3	0.7	-0.7
Systolic blood pressure, automated reading	0.6	1.9	5.8	1.4	2.4	1.1	-1.4	-0.3	-0.4	-1.3	0.9	1.8
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	4.1	-0.4	0.0	0.6	0.6	-0.8	-2.0	-0.8	0.6	1.5
Angina	0.2	0.3	1.3	0.0	-0.1	-0.1	-0.2	-1.2	0.9	-0.4	0.5	0.4
Medication for hormone replacement therapy	0.9	1.0	2.0	-1.4	0.6	1.1	-0.7	-1.3	-1.3	-1.1	0.1	0.7
Vitamin and mineral supplements	0.7	0.9	3.3	-0.6	-0.8	-1.8	-0.2	-0.3	0.9	-0.1	1.6	0.8
Supplements: Zinc	1.1	1.2	5.2	0.8	-0.3	0.6	2.3	1.3	-0.7	0.2	-1.4	-0.7
Medication: Co-codamol	0.3	0.3	1.5	0.2	-1.2	0.4	0.3	0.7	0.2	-0.0	-0.5	0.3
Medication: Metformin	0.9	1.3	3.5	-1.2	-0.2	1.0	1.1	-1.1	-1.1	-1.9	-1.2	0.8
Diabetes (father)	0.2	0.2	0.6	0.6	0.8	0.4	0.3	-0.1	0.3	-0.4	-0.7	-0.5
Diabetes (mother)	0.6	0.7	2.6	-0.1	-0.1	-0.3	1.6	-0.5	0.4	0.8	0.9	1.4
Severe depression (siblings)	0.6	0.7	3.0	-0.8	0.1	0.9	0.9	0.6	-0.5	-0.0	-0.4	-1.7
Pack years adult smoking proportion	1.5	2.3	12.9	1.3	0.8	0.4	-1.6	-0.5	-0.5	-0.8	3.6	1.1
Impedance of leg (right)	0.2	1.0	6.9	0.9	0.1	0.2	2.6	-0.0	-0.5	-0.2	-1.0	0.4
Leg fat-free mass (left)	0.4	2.3	6.4	-2.0	0.2	-1.4	-2.5	-1.4	1.8	0.2	1.7	0.2
Trunk fat percentage	0.9	3.7	12.7	0.8	1.1	-0.1	-2.8	-3.6	0.9	-0.7	2.8	1.3
Hand grip strength (right)	0.4	1.0	3.7	0.2	-0.5	0.2	1.9	0.3	1.7	1.1	-0.1	-0.9
Townsend deprivation index at recruitment	0.9	1.3	5.3	-0.5	-1.1	0.0	2.3	-1.5	1.3	-0.1	0.1	0.9
Current tobacco smoking	0.6	1.0	3.0	-1.2	0.3	0.4	1.7	-1.1	0.4	-0.4	0.4	-1.6
Average weekly fortified wine intake	1.0	1.2	5.1	-1.2	1.2	-0.8	-0.4	-0.2	0.5	-0.9	-1.0	-2.3
Maternal smoking around birth	0.9	1.3	4.0	-0.4	-0.8	-1.4	-0.8	-2.0	1.7	0.5	-0.1	0.8
Fed-up feelings	0.6	1.1	2.8	-0.5	0.7	-1.2	-1.7	0.9	1.6	1.1	-0.3	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.1	3.1	0.0	0.3	-0.9	0.7	-1.0	1.5	-1.7	-1.2	-1.1
Relative age voice broke	0.4	0.6	1.2	-0.3	-0.5	1.1	-1.0	-0.6	0.6	0.8	1.0	0.3
Taking other prescription medications	0.6	1.0	2.6	0.0	0.2	0.5	-0.9	-1.6	0.3	-0.5	1.6	1.6
Age when periods started (menarche)	0.1	0.2	0.5	0.2	0.0	0.1	-0.5	0.6	0.1	-0.1	0.7	0.6
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	3.7	-0.0	-0.2	0.5	0.6	-0.5	-0.7	-1.9	0.5	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.6	2.9	0.7	-1.6	1.5	1.7	-0.9	-0.5	-1.7	-1.3	-0.9
Tinnitus: Yes, but not now, but have in the past	1.1	1.1	2.7	0.1	0.2	1.4	-0.5	0.3	-1.6	-0.0	1.6	1.6
Qualifications: CSEs or equivalent	1.9	2.6	7.5	-0.8	-2.7	-2.4	0.6	-1.6	2.2	0.0	-1.1	0.2
Serious illness, injury or assault to yourself	1.2	1.5	5.4	-1.0	-0.1	0.0	-0.8	-2.3	0.8	0.9	1.7	1.4
High blood pressure	0.6	1.7	9.0	1.0	0.3	0.7	0.1	-3.0	-0.7	-2.0	0.5	0.2
Hayfever, allergic rhinitis or eczema	0.6	1.4	5.2	-1.3	0.1	-0.5	-0.1	2.0	0.4	2.3	0.6	0.8
Multivitamins +/- minerals	0.6	0.7	4.3	1.0	0.7	0.6	-0.2	0.2	0.2	-0.0	-2.1	-0.7
Stomach or abdominal pain in last month	1.3	1.6	4.9	-1.4	-0.7	-2.2	-0.2	-0.3	1.9	-1.0	-1.2	-1.0
Supplements: Glucosamine	1.3	1.7	4.9	-0.6	2.2	-0.9	-2.0	-1.4	1.3	-1.0	0.2	-0.5
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	1.7	-1.2	-0.7	0.4	-0.2	-1.3	-0.1	-0.1	1.3	1.2
Medication: Atenolol	1.2	1.5	4.3	-1.1	1.0	-0.4	-0.7	-2.1	1.5	-0.4	2.1	0.2
Medication: Levothyroxine sodium	0.8	1.3	5.3	-2.3	0.1	-1.4	-0.6	-1.1	1.0	0.1	1.2	0.4
Sitting height	0.3	2.1	6.1	-1.3	-0.7	-1.1	1.7	-2.5	0.3	-1.7	-0.8	-1.8
Chronic bronchitis/emphysema (father)	0.6	0.7	1.7	-0.6	1.3	-0.9	1.0	1.1	0.4	0.5	-0.9	0.6
High blood pressure (mother)	0.7	0.9	2.5	-0.9	-0.6	1.4	-1.3	0.5	-0.8	-0.1	-0.5	1.6
Body mass index (BMI)	0.5	2.0	6.7	0.1	0.2	-0.7	-2.3	-2.6	1.9	0.1	1.4	0.4
Impedance of leg (left)	0.2	1.0	6.4	1.3	0.1	0.3	2.5	-0.4	-0.6	-0.3	-0.7	0.2
Leg predicted mass (left)	0.4	2.2	6.5	-2.0	0.2	-1.3	-2.5	-1.4	1.7	0.2	1.6	0.2
Trunk fat mass	0.8	3.5	14.1	-0.1	0.6	-0.4	-2.9	-3.8	1.3	-0.6	2.5	0.8
Waist circumference	0.8	3.0	13.7	-1.3	-0.6	-1.6	-1.7	-3.7	2.4	-0.6	0.3	-0.4
Number of incorrect matches in round	1.5	2.4	7.7	1.2	-0.5	0.1	2.8	1.6	0.5	2.1	-2.3	-0.4
Past tobacco smoking	0.8	1.5	5.4	-1.0	-0.5	1.2	-0.2	2.3	-1.4	1.5	0.0	-1.2
Alcohol usually taken with meals	1.6	2.5	8.8	1.1	0.1	2.0	0.3	2.9	-3.0	0.4	0.3	0.5
Nervous feelings	0.5	0.9	3.5	0.7	0.9	1.3	-1.9	-0.0	-1.1	-0.2	0.2	-0.4
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	4.7	1.1	-0.9	0.4	-0.6	1.2	-0.6	-2.2	-1.1	-0.4
Hearing difficulty/problems with background noise	0.1	0.1	0.6	0.1	-0.5	0.1	0.8	0.2	0.1	0.2	0.2	-0.4
Hair/balding pattern: Pattern 2	0.4	0.5	2.4	0.1	0.6	-0.2	-0.6	1.0	0.2	1.5	0.0	-0.1
Had menopause	0.8	1.0	2.0	0.6	1.4	1.2	-1.3	0.5	-1.4	-0.9	-0.6	0.1
Had other major operations	0.5	0.6	2.0	-1.4	-0.9	0.5	0.7	-1.0	-0.3	0.9	0.6	-0.4
Forced vital capacity (FVC)	0.5	1.9	6.8	-0.1	-1.1	-0.9	2.6	1.0	1.4	0.6	-1.7	-1.3
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.5	3.7	0.0	-1.9	1.3	1.8	-1.5	-0.2	-1.0	-0.7	-1.2
Ever unenthusiastic/disinterested for a whole week	1.1	1.4	4.8	-0.3	-0.4	1.7	2.0	0.5	-0.1	-0.1	-2.2	-0.3
Qualifications: None of the above	1.1	2.3	7.0	-0.4	2.6	-1.0	-2.4	-1.0	-0.7	-0.6	1.4	1.7
Financial difficulties in last 2 years	0.3	0.5	1.2	-1.1	-0.9	0.3	0.8	-0.6	0.0	-0.4	-0.8	-0.3
Mouth/teeth dental problems	0.6	0.9	2.8	-0.6	-0.5	-0.6	1.7	-0.4	-0.0	-1.2	-0.1	-1.7
Heart attack	1.0	1.2	2.5	-1.1	-0.6	-1.6	1.4	-1.6	1.2	-0.9	0.2	-0.5
Allergy	0.6	1.5	7.0	1.2	-0.5	0.0	0.4	-1.5	-1.1	-2.6	-0.1	-1.1
Pain all over the body in last month	0.6	0.7	3.8	-0.5	1.2	-0.5	0.4	-0.2	1.9	0.1	0.2	-0.2
Diabetes (self-reported)	1.8	2.7	7.3	-1.9	-0.6	0.1	2.7	-2.4	-0.2	-2.3	-1.4	-0.1
Hayfever/allergic rhinitis (self-reported)	0.7	1.0	2.5	1.6	-0.4	0.4	0.0	1.6	-0.2	1.3	-0.5	1.2
Medication: Ramipril	0.3	0.4	1.3	1.1	-1.2	0.3	0.1	-0.1	-0.4	-0.6	0.4	-0.4
Medication: Simvastatin	2.1	3.1	16.6	-0.5	-0.1	0.2	-0.3	-4.1	0.4	-2.8	-1.7	0.1
Fluid intelligence score	0.5	1.1	3.6	0.4	1.0	0.6	-0.3	0.4	0.9	1.7	1.9	0.7
Illnesses of siblings	0.4	0.6	2.6	0.3	0.5	0.7	1.6	1.0	0.6	0.1	-0.6	-0.2
Neuroticism score	0.5	1.0	3.0	-0.2	-0.4	-1.1	-1.2	-0.8	1.7	-0.5	-0.2	-1.5
Weight	0.5	2.4	8.5	-1.0	0.1	-1.0	-2.4	-2.9	1.9	-0.2	1.5	0.1
Impedance of arm (right)	0.4	1.7	4.9	2.2	1.2	1.4	-0.4	0.9	-1.5	-0.3	1.4	1.4
Arm fat percentage (right)	0.9	3.6	12.5	0.7	0.9	-0.4	-3.5	-3.0	1.2	-0.0	2.7	0.9
Trunk fat-free mass	0.2	1.3	5.2	-2.3	-0.8	-1.1	-1.2	-0.8	1.4	0.6	0.3	-0.6
Hip circumference	0.3	1.3	4.8	0.2	1.2	-0.3	-2.2	-1.3	1.4	0.1	1.1	0.8
Time employed in main current job	0.6	0.7	2.3	0.0	-0.4	-1.5	-0.1	0.3	-0.2	-0.5	1.1	1.3
Alcohol intake versus 10 years previously	1.1	1.6	4.6	-0.5	-2.1	-0.2	2.0	-1.8	0.3	-0.2	0.4	1.4
Father’s age at death	1.3	1.7	6.0	-0.1	1.2	-0.1	-2.4	0.1	-0.2	-0.0	2.3	1.5
Worrier / anxious feelings	0.5	1.0	2.3	-1.3	-0.2	-1.5	-1.5	0.7	1.1	0.4	0.4	-1.0
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	1.7	0.1	0.0	-1.2	1.1	0.8	1.3	0.5	-0.7	-0.1
Falls in the last year	1.0	1.4	4.1	0.0	-0.3	-0.1	2.0	-0.7	1.9	0.3	2.0	-0.1
Hair/balding pattern: Pattern 3	1.3	1.9	4.5	-2.0	-0.4	-0.1	-1.0	-2.0	0.0	-2.1	-0.0	-1.8
Number of live births	1.0	1.4	4.1	-1.9	-1.0	-1.0	-1.1	-0.3	1.0	0.0	-2.0	-0.9
Forced expiratory volume in 1-second (FEV1)	0.6	2.0	10.7	0.0	-1.3	-0.7	3.3	0.9	0.3	0.2	-1.4	-1.5
Pulse rate	1.0	1.6	3.4	-0.2	-1.1	-1.9	1.1	-1.7	1.7	0.0	1.5	0.9
Happiness	0.3	0.4	0.9	-0.1	0.4	0.1	0.1	0.9	0.9	-0.6	-0.7	1.0
Noisy workplace	1.0	1.3	4.0	0.8	0.2	2.0	-0.9	-1.1	-1.3	-1.4	-1.0	0.3
Qualifications: A levels/AS levels or equivalent	0.3	0.6	2.1	-0.1	-0.8	-1.3	0.6	0.1	0.6	0.1	-0.0	-1.5
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.5	3.7	-0.9	0.7	-0.8	-0.8	-0.9	1.9	1.5	0.9	1.9
Mouth/teeth dental problems: Dentures	1.0	1.7	4.0	1.3	2.0	1.5	-1.6	0.6	0.0	0.9	0.9	1.7
Asthma	0.2	0.5	1.0	0.8	1.0	0.8	-0.5	0.8	0.5	0.9	0.3	-0.0
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	1.6	-1.2	-0.7	-0.9	-0.2	-0.7	0.8	1.3	0.1	-0.7
Medication: Cholesterol lowering	1.5	2.3	9.8	-1.1	-0.9	-0.1	0.7	-3.1	0.2	-2.5	-1.2	0.5
Depression (self-reported)	1.3	1.6	5.8	-0.0	-1.5	-1.2	0.3	-0.7	-0.4	-2.4	-1.5	-1.2
Medication: Lansoprazole	0.6	0.7	1.2	0.4	-1.0	1.0	0.6	-0.9	-0.1	-0.9	0.9	1.1
Prospective memory result	1.6	2.0	3.9	0.3	1.9	-0.4	-2.0	1.7	0.5	2.0	0.8	1.5
Lung cancer (father)	0.9	1.0	6.2	2.5	-0.6	0.0	-0.8	0.8	-0.3	1.1	-0.4	-0.4
Illnesses of mother	0.5	0.7	1.8	-0.4	0.2	-1.4	0.8	0.1	0.7	1.0	-0.4	-1.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.2	3.5	-0.4	-1.1	-0.9	1.9	1.4	0.7	-0.3	-0.3	-1.6
Pulse wave Arterial Stiffness index	0.9	1.0	3.0	-0.9	-0.8	-0.5	0.4	-1.7	-0.3	-1.6	-1.0	-0.9
Impedance of arm (left)	0.4	1.9	5.1	2.3	1.2	1.7	-0.6	0.8	-1.9	-0.3	1.5	1.0
Arm fat mass (right)	0.8	3.3	9.5	-0.1	0.3	-0.9	-3.0	-3.1	1.7	0.2	2.6	0.8
Trunk predicted mass	0.2	1.3	5.1	-2.2	-0.7	-1.1	-1.3	-0.8	1.4	0.6	0.3	-0.7
Standing height	0.1	0.8	4.5	-2.1	-0.5	-0.6	-0.1	-0.9	0.5	-0.6	0.6	-0.7
Length of working week for main job	1.7	1.9	5.9	-0.9	0.4	-1.7	-2.4	-1.5	0.8	-1.3	0.5	-1.5
Exposure to tobacco smoke at home	0.8	0.9	2.8	0.9	0.3	0.5	-0.1	-1.7	0.3	-0.9	0.6	1.7
Breastfed as a baby	0.4	0.4	1.7	-0.1	0.6	-0.1	-0.4	1.1	0.2	1.3	0.6	-0.5
Tense / ‘highly strung’	0.5	0.9	3.3	-0.3	-1.8	0.9	-0.3	-0.3	-1.8	-0.5	-0.2	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	2.5	0.7	0.0	0.4	-0.3	-0.3	-0.0	-0.9	0.6	-1.6
Hair/balding pattern: Pattern 4	0.1	0.3	0.7	-0.1	-0.6	0.0	0.4	0.4	-0.8	-0.8	0.4	0.3
Birth weight of first child	0.3	0.6	1.3	0.3	0.4	0.7	-0.8	-0.4	-0.7	-1.1	-1.1	-0.7
Peak expiratory flow (PEF)	0.2	0.6	2.8	0.9	-0.4	0.2	1.7	0.9	-0.7	0.4	-0.2	0.1
Pulse wave reflection index	1.4	1.7	3.1	-1.7	-1.2	-0.9	1.5	-1.4	0.3	-1.3	-1.8	-1.0
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.8	-0.2	-1.4	1.2	-0.1	0.7	-0.5	0.6	-1.1	-0.4
Loud music exposure frequency	0.4	0.4	2.2	-0.4	-0.1	-0.4	0.8	-0.2	0.5	0.4	-0.3	-1.5
Qualifications: O levels/GCSEs or equivalent	0.9	1.4	3.7	0.6	-1.4	-0.1	1.6	-0.5	0.8	-0.4	-1.9	-1.8
Mouth/teeth dental problems: Bleeding gums	0.8	1.1	3.5	-0.4	-0.8	-1.5	-1.9	-0.4	0.1	1.4	0.7	0.9
Blood clot in the leg (DVT)	0.6	0.8	1.8	-0.5	-1.1	-0.0	0.9	-0.8	0.7	0.7	-1.4	-1.3
Medication: Paracetamol	0.3	0.4	1.4	-0.3	-0.7	-0.5	0.7	-0.1	1.2	0.4	-0.9	0.6
Headache pain in last month	0.2	0.3	1.0	0.4	-0.3	-0.2	-0.6	0.6	0.2	0.6	-1.0	-0.4
Medication for cholesterol, blood pressure or diabetes	1.0	1.6	8.0	0.8	0.1	-0.3	-0.4	2.8	0.2	2.2	0.3	-0.5
Glaucoma (self-reported)	0.2	0.2	0.6	-0.2	0.8	-0.3	0.6	0.8	-0.0	-0.2	0.6	0.2
Gout (self-reported)	1.1	1.5	3.6	0.7	1.7	1.8	-1.6	0.3	-0.8	0.6	1.9	0.1
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	2.4	-1.5	-0.4	-0.2	-0.7	-0.5	-0.3	0.0	1.2	-0.6
Medication: Amlodipine	0.9	1.3	5.5	-1.0	-0.2	-0.4	-1.9	-2.4	0.2	-0.8	0.5	-0.2
Medication: Ventolin 100micrograms inhaler	0.8	1.0	2.8	1.7	0.8	0.2	-1.1	0.5	1.1	1.6	0.2	-0.4
Birth weight	2.2	4.9	13.7	1.6	2.7	1.7	-3.7	-0.9	-2.6	-2.4	1.7	1.0
Chronic bronchitis/emphysema (mother)	0.5	0.6	2.6	-0.3	-0.6	-0.0	0.5	-0.6	1.6	0.4	-1.0	-0.6
High blood pressure (siblings)	0.4	0.6	3.0	0.8	0.3	0.5	-1.7	-0.8	-0.9	0.3	0.5	0.1
Forced vital capacity (FVC), Best measure	0.3	1.2	2.7	-0.4	-1.0	-0.9	1.6	1.5	1.3	-0.1	-0.7	-1.5
Body fat percentage	0.9	3.4	13.5	0.7	1.0	-0.3	-2.7	-3.7	1.2	-0.5	2.4	1.1
Leg fat percentage (right)	0.7	2.4	13.2	0.5	0.6	-0.7	-1.6	-3.6	1.6	-0.4	1.2	0.8
Arm fat-free mass (right)	0.4	1.9	5.4	-2.3	-0.7	-1.6	-1.2	-1.9	1.8	0.4	0.5	-0.5
Exposure to tobacco smoke outside home	0.7	1.0	2.6	0.3	0.5	1.3	-1.4	-1.4	-0.1	-0.6	-1.6	0.1
Comparative body size at age 10	0.3	0.7	2.2	-0.9	0.1	0.3	-1.5	-0.9	-0.4	-0.0	0.5	1.4
Number of full brothers	0.4	0.5	2.0	-0.0	0.4	-1.2	-0.4	-0.3	-0.3	-0.3	-0.8	-1.4
Worry too long after embarrassment	0.7	1.2	3.9	0.5	0.4	0.1	1.4	-0.5	-0.0	-1.6	-1.2	-2.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.0	4.2	0.7	-0.1	-0.7	0.6	0.2	1.8	-0.1	-0.5	-2.0
Wheeze or whistling in the chest in last year	0.4	0.8	2.3	0.8	1.5	0.9	0.5	-0.1	0.3	0.4	-1.3	-1.1
Number of children fathered	1.4	1.6	6.1	-0.3	-0.7	-0.6	0.1	-1.9	-0.9	-2.5	-0.5	-1.5
Reason for reducing amount of alcohol drunk: Health precaution	0.8	1.0	2.8	1.2	-0.3	1.7	-0.3	-0.7	-0.8	-0.7	0.7	1.4
Age at first live birth	1.2	2.2	5.8	1.9	-0.0	1.7	0.7	2.4	-1.6	0.5	-2.0	-0.3
Pulse wave peak to peak time	1.0	1.2	3.5	1.0	0.8	0.8	-0.3	1.9	0.1	1.7	1.0	0.9
Health satisfaction	0.4	0.5	2.7	0.1	-0.0	0.2	0.0	-0.5	0.2	-1.6	0.5	1.1
Shortness of breath walking on level ground	1.2	1.4	8.1	-2.9	-0.8	-0.5	0.6	-0.7	-0.5	-0.0	-1.2	1.1
Qualifications: College or University degree	0.2	0.6	2.8	-0.4	0.7	-0.2	0.1	1.7	-0.7	0.1	-0.7	-1.1
Eye problems/disorders: None of the above	0.9	1.1	2.6	0.2	-1.2	-1.6	-0.6	0.4	1.6	0.6	-1.4	-0.5
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.8	-0.3	-0.3	-0.4	0.6	-0.9	0.7	-0.6	-1.0	-1.4
Emphysema/chronic bronchitis	0.3	0.4	1.1	0.7	0.7	-0.5	0.4	0.2	1.0	-0.3	-0.9	-0.0
Medication for pain relief, constipation, heartburn	0.4	0.7	2.2	0.6	0.1	-0.1	-1.0	1.5	-0.5	1.1	1.1	0.1
Neck or shoulder pain in last month	0.8	1.1	2.6	-0.9	-1.6	-0.6	1.0	-1.6	0.9	-0.2	0.2	1.6
Medication: Blood pressure	0.6	1.0	3.1	-0.2	0.3	1.2	0.5	-1.8	-0.9	-1.6	-0.7	-0.1
Angina (self-reported)	0.2	0.3	1.3	-0.3	-0.2	-0.2	-0.4	-1.2	0.6	-0.3	0.5	0.6
Migraine (self-reported)	0.7	0.9	2.0	1.4	0.8	0.9	-0.6	0.5	-1.2	-0.2	-1.0	-1.2
Medication: Ibuprofen	0.3	0.3	1.0	-0.3	-0.8	0.4	0.3	-0.3	0.1	1.0	-0.2	-0.9
Medication: Allopurinol	0.6	0.8	3.3	-0.0	0.5	1.8	-0.0	-0.6	-1.3	-0.4	1.1	-0.1
Medication: Omeprazole	1.6	1.9	7.1	1.6	1.3	1.2	0.3	-1.1	-0.2	-2.7	-1.7	0.4
Medication: Seretide 50 evohaler	2.0	2.3	5.2	-1.1	1.5	-1.8	0.1	1.3	2.3	2.0	-1.3	-1.1
Mean time to correctly identify matches	0.2	0.4	1.2	0.2	-0.2	0.6	1.0	1.1	-0.6	0.8	0.3	-0.0
Heart disease (mother)	0.6	0.7	2.2	-0.4	1.1	-0.5	0.7	-0.3	-1.5	-1.3	-0.3	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.4	1.7	4.8	0.5	1.2	-1.5	1.0	-2.1	2.2	0.0	1.1	0.6
Whole body fat mass	0.8	3.3	13.4	-0.3	0.5	-0.7	-2.6	-3.7	1.7	-0.3	2.3	0.8
Leg fat mass (right)	0.7	2.9	13.1	-0.6	0.4	-1.0	-2.2	-3.6	1.9	-0.2	1.7	0.7
Arm predicted mass (right)	0.4	2.1	6.4	-2.5	-0.8	-1.6	-1.2	-1.9	1.8	0.5	0.7	-0.3
Pulse rate, automated reading	0.6	1.8	6.0	-0.8	-0.9	-2.5	-0.6	-0.7	1.9	0.8	2.0	0.2
Alcohol intake frequency.	0.8	1.8	3.6	-1.2	-1.1	-1.9	-0.1	-1.1	-0.0	1.9	1.5	1.6
Comparative height size at age 10	0.2	1.0	5.4	-2.3	-1.3	-0.3	0.8	-0.4	0.0	-0.2	-0.5	-1.1
Number of full sisters	0.5	0.6	1.9	0.5	0.3	0.1	-0.9	-1.4	-0.1	-0.4	1.4	0.0
Suffer from ‘nerves’	0.7	1.0	3.1	-1.8	-1.1	0.4	-1.3	-0.6	-0.6	-0.4	-0.6	-1.3
Overall health rating	0.8	1.7	2.9	-1.7	-1.5	-1.4	-0.2	-1.2	1.4	-0.4	1.5	1.6
Chest pain or discomfort	0.8	1.2	3.8	-0.6	0.0	0.4	1.4	-1.9	1.0	-0.3	0.1	-1.7
Had major operations	1.4	1.7	7.8	-2.8	0.3	-1.9	-0.8	0.5	0.9	0.9	0.1	1.0
Age at last live birth	1.4	2.0	10.9	0.2	-0.4	0.8	0.7	2.3	-0.4	0.8	-3.3	-0.0
Family relationship satisfaction	1.1	1.3	5.1	1.2	0.3	1.7	-1.1	2.3	-0.4	0.6	-0.6	0.2
Leg pain on walking	0.7	0.9	2.5	-1.3	-0.5	-0.8	0.4	-1.2	1.6	-0.8	0.2	0.9
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.5	4.2	0.5	-1.0	2.0	0.3	0.3	0.6	1.4	2.0	-1.1
Commuting to job workplace: Car/motor vehicle	0.7	0.8	1.8	0.4	-1.2	0.9	-1.3	1.1	-0.7	0.8	0.3	-0.3
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.9	0.3	-0.7	-0.5	1.0	-0.3	-0.7	-0.8	0.3	-1.4
Medication: Aspirin	1.0	1.3	5.2	-1.3	-0.1	0.3	0.5	-2.3	-0.4	-1.7	-0.3	-1.1
Supplements: Vitamin C	1.3	1.5	3.8	0.7	0.3	1.6	1.8	0.1	-1.9	-0.1	-1.1	-1.6
Knee pain experienced in last month	1.0	1.5	4.3	-1.0	1.2	-1.1	0.3	-1.7	2.1	-0.3	1.3	-0.6
Hypertension (Self-reported)	0.5	1.4	6.3	1.3	0.8	0.9	-0.4	-2.5	-0.4	-1.7	0.3	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.3	3.1	1.1	-0.6	1.8	1.4	-0.9	-0.7	-1.1	-1.5	0.0
Illnesses of father: Heart disease	0.1	0.2	0.5	0.3	0.2	0.2	0.0	0.7	-0.6	-0.2	-0.1	-0.6
Illnesses of siblings: Diabetes	0.4	0.5	1.7	-0.5	-0.7	0.7	1.3	-0.7	-0.8	-0.4	-0.5	-0.1
Smoking status: Previous	1.0	1.5	2.9	1.1	0.5	-1.7	-0.4	-1.6	1.4	-1.3	-0.1	1.6
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.3	0.6	-0.7	-0.3	0.1	0.7	0.5	0.6	-0.4	-0.6	0.2
Whole body fat-free mass	0.3	1.7	5.2	-2.3	-0.3	-1.3	-1.9	-1.2	1.6	0.3	0.8	-0.3
Leg fat-free mass (right)	0.4	2.0	6.7	-1.8	0.2	-1.2	-2.6	-1.3	1.6	0.2	1.6	0.0
Arm fat percentage (left)	0.9	3.7	13.8	0.9	0.9	-0.2	-3.7	-2.9	1.1	-0.1	2.7	0.9
Average weekly red wine intake	0.8	1.2	6.6	-1.2	-2.6	-0.1	0.4	0.2	-1.1	0.3	0.0	0.9
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.3	-0.5	-0.7	-0.3	0.1	-0.3	0.6	-0.6	1.0	1.2
Mood swings	0.3	0.5	2.7	0.4	-0.2	-0.4	-1.7	-0.2	1.1	-0.2	-0.4	0.5
Loneliness, isolation	1.0	1.4	3.1	-1.7	-1.0	-1.2	-0.4	-0.8	1.0	-0.5	-1.6	-1.8
Long-standing illness, disability or infirmity	1.8	2.7	6.0	-2.1	1.5	-0.4	-1.0	-2.4	1.7	-0.2	2.2	1.6
Ever had bowel cancer screening	0.4	0.5	1.5	-0.2	0.0	0.5	-0.7	-0.6	-1.1	-1.2	-0.3	0.5
Diabetes diagnosed by doctor	1.7	2.9	8.5	-2.5	-1.1	-0.0	2.9	-2.6	0.0	-1.4	-1.1	0.3
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	4.4	-2.1	-2.0	-1.2	0.9	0.3	0.4	0.2	-0.2	-1.6
Friendships satisfaction	0.6	0.7	2.3	-0.5	-0.1	0.6	0.0	1.1	1.5	1.2	1.1	0.1
Qualifications: nursing, teaching	1.2	1.9	5.1	0.7	-0.3	1.6	0.4	0.1	-1.9	-1.4	-2.3	-1.7
Commuting to job workplace: Walk	1.2	1.3	3.1	-0.9	0.9	-1.3	-0.6	-1.6	1.3	-1.8	0.2	0.8
Eye problems/disorders: Cataract	0.7	0.8	3.6	0.2	0.9	1.9	0.3	-0.4	-0.9	-0.3	1.3	0.1
Mouth/teeth dental problems: Mouth ulcers	0.8	1.2	3.2	0.9	-1.8	1.5	0.9	0.7	-1.1	-1.2	-0.8	0.7
Medication for cholesterol	0.9	1.3	4.0	-0.8	-1.2	-1.1	1.2	2.0	1.0	1.0	-0.9	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	4.0	0.4	0.3	-0.4	-1.0	-1.8	-0.8	-2.0	1.4	0.6
Back pain experienced in last month	0.8	1.1	3.1	-0.6	1.0	-0.3	-0.9	-0.3	1.8	1.3	0.9	1.4
Mineral and other dietary supplements	0.5	0.7	2.7	-0.6	-0.9	-0.2	-1.4	-0.1	-0.9	-0.1	1.6	-0.2
Breast cancer (self-reported)	1.0	1.2	4.3	-0.6	-0.3	1.0	1.9	0.1	0.9	0.5	-2.1	-0.5
Asthma (self-reported)	0.3	0.6	1.2	0.9	0.9	1.0	-0.4	0.9	0.6	1.1	0.5	0.0
Osteoporosis (self-reported)	0.7	0.8	2.7	-0.7	1.7	0.6	0.5	0.0	1.5	0.6	0.1	-0.9
Osteoarthritis (self-reported)	1.1	1.4	4.1	-2.0	0.3	-1.2	-1.4	-0.6	0.5	0.3	1.5	1.4
Medication: Aspirin	1.1	1.5	4.2	-0.8	0.2	1.4	0.4	-2.0	-0.6	-2.0	-0.2	-1.5
Medication: Gliclazide	0.7	0.8	2.9	-1.3	0.9	0.3	0.4	0.9	0.2	0.2	0.8	1.7
Illnesses of father: None of the above (group 1)	0.3	0.3	1.4	0.7	0.1	0.7	-0.3	-0.3	-0.0	0.5	0.4	1.2
Smoking status: Current	0.6	0.9	2.4	-1.0	0.4	0.5	1.4	-1.3	0.2	-0.6	0.2	-1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	2.9	0.9	-0.1	0.1	1.7	0.9	-0.6	-1.1	-1.3	-0.3
Whole body water mass	0.3	1.9	5.0	-2.2	-0.4	-1.3	-2.1	-1.2	1.6	0.4	1.1	-0.4
Leg predicted mass (right)	0.4	2.1	6.9	-1.8	0.2	-1.1	-2.6	-1.4	1.5	0.1	1.7	0.0
Arm fat mass (left)	0.8	3.5	11.0	0.1	0.3	-0.7	-3.3	-3.2	1.5	0.1	2.6	0.7
Number of self-reported non-cancer illnesses	0.7	1.2	2.7	1.4	1.5	1.2	-0.4	-1.7	0.9	-0.3	0.1	1.3
Average weekly champagne plus white wine intake	0.5	0.7	2.5	0.2	0.6	-0.1	1.0	1.6	-0.6	0.2	-0.8	-1.0
Miserableness	0.5	0.8	2.4	0.2	-0.8	0.4	-0.8	-0.5	0.9	-1.5	-0.2	-1.6
Guilty feelings	0.8	1.2	3.9	-0.5	-0.2	-1.3	-1.1	-0.8	2.0	0.1	-1.2	-1.3
Wears glasses or contact lenses	1.0	1.2	3.4	1.7	-0.2	0.8	-0.8	1.6	-0.3	0.1	-0.3	1.9
Ever taken oral contraceptive pill	1.7	1.9	8.5	0.9	0.9	1.6	-0.2	-0.6	-0.5	-2.9	-0.7	-1.8
Hearing aid user	0.6	0.7	1.5	-0.2	0.7	-1.2	-1.0	0.8	-0.1	1.1	0.9	0.7
Mother’s age at death	0.4	0.5	1.8	-1.3	-1.1	0.5	0.6	0.1	-0.4	0.4	-0.4	-0.8
Financial situation satisfaction	0.6	0.8	3.0	-1.7	-1.3	-1.1	0.2	-0.1	0.4	-0.6	0.4	-0.6
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.0	-0.9	-0.8	-0.4	0.6	-0.9	0.3	0.8	-1.0	-0.7
Commuting to job workplace: Public transport	0.8	1.0	4.6	-1.2	0.5	-1.0	2.1	-0.5	0.5	-0.3	0.8	-0.7
Eye problems/disorders: Glaucoma	0.5	0.6	3.0	-0.3	0.2	0.2	0.7	1.0	-0.6	0.1	1.7	0.6
Medication: Blood pressure	0.6	1.1	1.8	1.3	1.2	1.1	-1.2	-1.3	-1.0	-0.8	0.5	-0.8
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.3	0.6	-0.9	-0.9	1.1	-0.8	0.0	0.1	-0.9	-0.1
Supplements: Fish oil (including cod liver oil)	1.1	1.5	6.7	-0.1	-0.5	0.1	2.6	-1.2	0.6	-0.8	-2.0	-0.2
High cholesterol (Self-reported)	1.1	2.0	11.6	-0.2	-0.4	0.1	-0.5	-3.4	1.1	-2.0	-0.4	-0.5
Medication: Bendroflumethiazide	0.4	0.6	2.9	0.4	1.7	0.3	-0.3	-0.6	-0.4	-0.8	-0.6	-1.0
Medication: Paracetamol	0.4	0.6	1.4	-0.8	-0.7	-0.5	0.9	-0.0	1.2	0.8	-0.5	0.9
Medication: Lisinopril	0.7	0.9	3.4	-1.3	0.6	-0.5	-1.0	-1.8	0.4	-0.7	1.0	0.1
Medication: Atorvastatin	0.7	0.9	2.8	-0.8	-1.4	-1.1	0.7	-1.7	0.6	-0.7	0.2	-0.1
Illnesses of father: High blood pressure	0.5	0.6	1.3	0.2	-0.5	-1.0	0.7	-0.7	1.1	-1.1	-0.3	-0.9
Alcohol drinker status: Never	0.2	0.3	0.6	0.5	-0.0	-0.5	-0.6	-0.3	-0.5	-0.7	0.5	0.7
Ever smoked	0.6	1.1	3.0	0.6	-0.0	-0.7	1.7	-1.7	0.9	-1.4	-0.3	-0.2
Basal metabolic rate	0.4	2.0	4.4	-2.1	-0.3	-1.4	-2.1	-1.7	1.8	0.3	1.0	-0.3
Leg fat percentage (left)	0.7	2.6	13.7	0.5	0.6	-0.8	-1.8	-3.7	1.6	-0.4	1.4	0.7
Arm fat-free mass (left)	0.4	2.2	4.7	-2.2	-0.6	-2.0	-1.5	-1.9	2.0	0.3	0.7	-0.4
Number of operations (self-reported)	0.6	0.8	3.5	-1.9	-1.2	-0.1	-0.3	-0.6	-0.5	0.7	0.9	0.7
Average weekly beer plus cider intake	0.9	1.3	6.3	0.6	-0.1	-0.6	0.5	-2.5	0.1	-0.6	1.9	-0.3
Irritability	0.6	1.0	4.2	-0.5	-2.0	-0.5	-0.5	0.0	1.4	1.2	0.3	1.0
Risk taking	0.3	0.5	1.5	-0.4	-0.2	0.3	1.2	-0.3	1.2	0.9	-0.2	-0.5
Ever had prostate specific antigen (PSA) test	1.8	2.0	6.1	0.3	0.2	2.5	-0.5	1.8	-2.5	-1.0	-1.0	-0.9
Fractured/broken bones in last 5 years	1.1	1.4	3.2	-1.8	-0.7	-1.7	-1.0	-1.2	-0.1	-0.2	-0.9	-1.4
Age started oral contraceptive pill	1.7	2.1	7.1	1.6	2.0	1.2	-1.2	0.8	-1.1	-0.3	0.6	2.7
Diastolic blood pressure, automated reading	0.4	1.2	3.3	1.8	0.1	-0.6	-0.4	-0.7	1.0	-1.2	0.9	1.8
Ever depressed for a whole week	0.8	0.9	4.3	0.1	0.1	0.4	2.1	1.1	1.1	0.8	-0.1	-0.9
Unable to work because of sickness or disability	0.8	1.1	2.0	-0.5	-0.4	-1.2	0.8	-1.3	1.0	-1.2	0.9	1.4
Commuting to job workplace: Cycle	0.7	0.9	2.1	1.0	-0.8	1.2	0.1	1.0	-0.6	-0.8	-1.4	-0.8
Myopia	0.4	0.6	2.7	-0.1	-0.1	-0.6	1.6	-0.7	1.0	-0.7	0.4	0.1
Vascular/heart problems diagnosed by doctor	0.6	1.8	9.9	-1.2	-0.7	-0.2	-0.6	3.1	0.1	1.8	-0.4	-0.5
Cholesterol lowering medication	0.9	1.4	6.5	1.1	0.3	0.5	0.6	-2.5	0.5	-1.7	-0.5	-0.8
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	4.0	2.0	1.2	1.4	0.0	-1.2	0.2	-2.0	-1.3	0.5
Pain experienced in last month	0.4	0.7	3.1	0.0	-0.5	0.5	-0.4	-0.5	-1.8	-1.4	0.2	0.0
Supplements: Calcium	0.5	0.6	2.7	-0.6	0.5	-0.6	1.6	0.5	0.4	0.5	0.3	-0.9
Basal cell carcinoma (self-reported)	0.8	0.9	4.5	-2.1	-0.8	-1.6	0.3	-0.2	0.2	-0.7	-0.4	-0.2
Heart attack/myocardial infarction (self-reported)	1.2	1.5	3.2	-1.3	-0.6	-1.8	1.6	-1.8	1.3	-0.9	0.0	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.5	0.7	1.1	-0.9	-0.9	-0.4	0.5	-1.0	0.8	0.9	-0.7	-1.0
Heart disease (siblings)	0.4	0.5	1.3	-0.5	0.4	-0.8	-0.6	-0.3	-1.1	-0.3	0.2	1.1
Alcohol drinker status: Previous	0.5	0.6	1.8	-0.1	1.0	0.2	-0.9	-0.8	-0.9	0.1	1.3	0.2
Pack years of smoking	2.1	3.0	15.7	1.6	1.0	0.7	-1.6	-0.5	-0.9	-0.9	4.0	1.7
Impedance of whole body	0.2	0.9	3.4	1.8	0.8	0.9	0.9	0.1	-1.1	-0.3	0.5	0.7
Leg fat mass (left)	0.8	3.0	13.2	-0.6	0.4	-1.1	-2.1	-3.6	1.9	-0.1	1.8	0.5
Arm predicted mass (left)	0.5	2.3	5.3	-2.3	-0.3	-1.8	-1.8	-2.0	2.0	0.2	0.9	-0.4