Hub : Genes

UBXN2A

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.22 0.044 0.0e+00 0.183 0.222 0.235 0.221 0.232 9.3e-22 1.3e-26 3.0e-28 1.7e-26 8.6e-28
2 GTEx Adipose Subcutaneous 0.06 0.026 5.9e-04 0.043 NA 0.031 NA 0.037 2.0e-04 NA 1.3e-03 NA 5.2e-04
3 GTEx Adipose Visceral Omentum 0.10 0.041 4.4e-04 0.082 NA 0.031 NA -0.002 4.7e-05 NA 9.8e-03 NA 4.1e-01
4 GTEx Adrenal Gland 0.42 0.084 9.8e-09 0.081 NA 0.217 NA 0.142 7.8e-04 NA 2.6e-08 NA 8.5e-06
5 GTEx Artery Aorta 0.20 0.065 2.4e-07 0.088 NA 0.069 NA 0.079 1.4e-05 NA 1.1e-04 NA 4.1e-05
6 GTEx Artery Tibial 0.12 0.040 1.6e-07 0.062 NA 0.090 NA 0.080 1.2e-05 NA 1.5e-07 NA 7.4e-07
7 GTEx Breast Mammary Tissue (Male) 0.34 0.144 7.6e-03 0.022 NA 0.113 NA -0.006 1.0e-01 NA 1.4e-03 NA 4.6e-01
8 GTEx Cells Transformed fibroblasts 0.12 0.042 1.1e-05 0.073 NA 0.117 NA 0.113 3.7e-06 NA 4.7e-09 NA 7.9e-09
9 GTEx Colon Transverse 0.11 0.050 3.1e-03 0.012 NA 0.035 NA 0.013 8.6e-02 NA 8.7e-03 NA 7.3e-02
10 GTEx Esophagus Mucosa 0.12 0.048 5.9e-04 0.063 NA 0.040 NA 0.053 4.9e-05 NA 1.1e-03 NA 1.9e-04
11 GTEx Esophagus Muscularis 0.08 0.036 3.5e-03 0.066 NA 0.056 NA 0.056 7.6e-05 NA 2.7e-04 NA 2.4e-04
12 GTEx Heart Atrial Appendage 0.08 0.036 6.7e-03 0.016 NA 0.008 NA 0.018 5.9e-02 NA 1.4e-01 NA 5.2e-02
13 GTEx Lung 0.09 0.032 3.6e-05 0.060 NA 0.068 NA 0.062 2.4e-05 NA 6.1e-06 NA 1.6e-05
14 GTEx Muscle Skeletal 0.10 0.032 1.0e-06 0.045 NA 0.024 NA 0.030 3.0e-05 NA 2.0e-03 NA 5.5e-04
15 GTEx Nerve Tibial 0.14 0.050 1.3e-04 0.026 NA 0.044 NA 0.047 5.4e-03 NA 4.4e-04 NA 2.9e-04
16 GTEx Skin Not Sun Exposed Suprapubic 0.12 0.047 1.7e-04 0.059 NA 0.116 NA 0.074 3.8e-04 NA 6.8e-07 NA 7.0e-05
17 GTEx Skin Sun Exposed Lower leg 0.08 0.032 2.1e-04 0.038 NA 0.031 NA 0.019 4.0e-04 NA 1.3e-03 NA 1.0e-02
18 GTEx Small Intestine Terminal Ileum 0.18 0.070 1.3e-03 0.083 NA 0.156 NA -0.013 6.5e-03 NA 2.5e-04 NA 8.3e-01
19 GTEx Spleen 0.31 0.112 4.5e-05 0.107 NA 0.169 NA 0.130 1.1e-03 NA 4.1e-05 NA 3.3e-04
20 GTEx Stomach 0.13 0.054 1.3e-03 0.145 NA 0.139 NA 0.108 1.9e-07 NA 3.6e-07 NA 8.0e-06
21 GTEx Whole Blood 0.17 0.049 1.3e-08 0.070 NA 0.075 NA 0.087 4.9e-07 NA 2.0e-07 NA 2.0e-08
22 METSIM Adipose 0.07 0.022 9.3e-08 0.033 0.064 0.055 0.065 0.044 7.7e-06 6.4e-10 1.2e-08 5.3e-10 2.8e-07
23 ROSMAP Brain Pre-frontal Cortex 0.03 0.015 8.4e-03 0.014 0.009 0.009 0.012 0.017 6.2e-03 2.3e-02 2.4e-02 1.0e-02 2.2e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Alzheimer’s Disease (in mother) 3.6 4.1 7.4 -0.0 -2.3 -2.7 -1.9 -2.5 -2.3 -1.3 -1.8 -2.2 -1.8 -2.1 -0.9 -2.4 -2.6 -1.8 -2.0 -1.8 -1.8 -2.7 -2.4 -2.4 -1.7 -0.5
Alzheimer’s Disease (in father) 1.4 1.6 7.1 0.8 -0.9 -1.5 -1.9 -1.3 -0.8 0.6 -0.9 -0.5 -0.9 -0.6 -0.9 -0.9 -1.1 -1.7 -1.7 -0.9 -1.7 -1.0 -0.8 -1.1 -1.1 2.7
Alzheimer’s Disease (including proxy) 2.4 3.4 6.4 0.5 -1.9 -2.5 -1.5 -2.4 -1.9 -0.8 -1.4 -1.9 -1.8 -1.7 -1.4 -2.1 -2.3 -2.2 -2.2 -1.7 -1.6 -1.7 -2.2 -1.9 -1.7 1.4
Crohns Disease (2017) 0.5 1.1 5.8 2.4 -1.0 -0.7 -0.1 -0.0 -0.4 0.1 0.0 -0.8 0.1 0.3 -1.7 -0.7 -0.2 0.4 1.6 -1.0 -0.4 -1.3 0.0 -0.5 -1.9 1.9
Irritable Bowel Disease (IBD) 0.7 1.7 10.0 3.2 -1.4 -0.3 0.0 0.4 -0.5 -0.6 0.2 -1.6 0.6 0.4 -2.3 -0.9 0.1 1.3 1.2 -1.7 -0.4 -0.9 -0.3 -0.6 -2.2 2.4
Ulcerative Colitis (UC) 0.4 0.8 3.9 2.0 -0.7 0.6 0.2 0.7 0.1 -0.5 0.2 -1.1 0.8 0.5 -1.1 -0.3 0.4 1.7 0.6 -1.2 0.0 0.4 -0.3 -0.0 -1.0 1.6
Major Depression (MDD) 0.5 0.6 1.5 -1.1 0.8 0.8 0.5 0.8 0.0 0.2 0.6 0.7 0.6 0.4 1.2 0.8 0.7 0.9 0.1 0.5 1.0 0.4 0.9 0.7 1.2 -0.8
Reaction Time 4.7 9.0 27.9 3.0 -3.3 -3.0 -4.0 -2.7 -3.0 -0.8 -3.2 -3.2 -1.2 -1.2 -3.5 -3.1 -2.6 -0.3 -2.4 -3.1 -5.3 -3.5 -2.2 -3.8 -3.2 2.9
Verbal and Numeric Reasoning (VNR) 4.9 11.9 28.2 -1.0 -3.8 -3.5 -3.5 -3.5 -4.3 -2.3 -4.3 -4.2 -3.0 -3.4 -0.4 -4.0 -4.1 -1.3 -3.7 -3.3 -4.0 -5.3 -4.0 -4.4 -1.3 -0.5
Breast Cancer 0.4 1.0 4.0 -1.6 1.1 2.0 1.3 0.5 0.8 1.7 0.9 0.6 0.1 0.0 1.5 0.5 0.2 0.6 0.1 0.8 1.0 1.1 0.4 0.7 1.3 -1.0
Ovarian Cancer 0.2 0.3 1.0 -0.1 -0.6 -0.2 -0.2 -0.4 -0.5 0.1 -0.6 -1.0 -0.1 -0.4 -0.2 -0.6 -0.8 -0.3 -0.1 -0.1 -0.7 -0.9 -0.8 -1.0 0.2 0.0
Prostate Cancer 1.0 1.4 7.5 2.7 -0.9 -1.4 -0.8 0.1 0.0 -0.0 -0.1 -1.4 0.8 0.7 -2.5 -0.5 0.3 0.4 -0.7 -0.8 -0.8 -0.1 -0.3 0.2 -2.2 2.1
Age at First Birth 0.3 0.4 2.6 -0.2 0.6 -0.3 0.3 1.2 0.8 0.2 0.7 0.7 0.4 0.4 -0.2 0.6 1.0 -0.0 -0.2 -0.0 1.6 0.6 0.7 0.8 0.4 0.8
Bipolar Disorder 0.6 0.6 3.1 -1.8 -0.2 0.3 -0.4 -0.4 -0.5 0.4 -0.9 -0.5 -0.3 -0.6 1.4 -0.5 -0.6 0.3 0.3 0.0 -0.9 -0.1 -0.4 -0.8 1.7 -1.1
Body Mass Index (BMI) (2010) 0.8 1.2 2.3 0.4 0.8 1.3 1.4 1.2 1.3 0.9 0.9 1.4 1.2 1.5 0.1 1.3 1.3 1.3 0.4 0.7 1.1 1.2 1.2 1.3 -0.2 0.1
Coronary Artery Disease (CAD) 1.6 2.0 7.8 -1.5 1.6 1.5 0.9 0.8 1.6 1.4 1.9 1.6 0.5 0.4 1.7 1.5 1.3 -0.1 0.4 1.2 1.9 2.8 0.9 1.8 1.4 -1.1
Crohns Disease (2012) 0.3 0.5 3.0 -1.7 -0.1 0.3 -0.0 -0.6 -0.2 0.2 -0.0 -0.3 -0.5 -0.7 1.1 -0.3 -0.3 -0.3 -1.7 0.0 -0.3 0.3 -0.6 -0.1 0.9 -0.9
Mean Putamen Volume 0.5 0.6 2.2 1.1 0.3 0.1 1.5 0.6 -0.0 0.1 0.3 -0.3 1.3 1.1 -0.7 0.4 0.8 1.4 0.8 0.3 0.3 -0.7 0.5 0.3 -0.4 1.0
Fasting Glucose 3.3 4.0 8.5 0.0 2.1 2.9 0.2 2.0 2.5 0.6 2.5 2.0 2.2 2.3 0.7 2.3 2.1 2.6 1.8 2.9 1.6 2.2 2.3 1.8 0.4 -1.7
HbA1C 2.9 3.2 15.9 -3.8 -0.3 1.5 -0.6 -1.7 -1.1 -1.1 -0.3 -0.5 -1.8 -2.2 3.6 -0.7 -1.4 -0.2 -0.6 -0.2 0.0 -0.5 -1.9 -1.3 2.4 -4.0
HDL Cholesterol 1.2 1.9 10.4 1.2 0.6 1.4 1.0 1.8 1.2 -0.2 0.6 0.7 2.1 2.3 -0.3 1.2 1.9 3.2 1.8 0.7 0.5 0.7 1.5 1.3 0.2 0.6
LDL Cholesterol 0.9 1.3 3.8 -0.3 1.2 1.5 0.2 1.3 1.1 0.9 1.2 0.9 1.2 1.0 0.8 1.2 1.1 1.9 1.2 1.4 1.6 1.2 0.8 0.7 0.7 -1.6
Lupus 0.5 0.7 4.4 -1.2 -0.4 0.2 -2.1 -0.7 -0.4 1.0 -0.7 0.0 -1.2 -1.0 1.1 -0.4 -1.0 -0.2 0.8 0.1 -0.6 -0.2 -0.5 -0.9 1.1 -0.7
Neuroticism 2.3 3.4 6.4 -0.8 2.1 2.5 0.6 2.3 1.6 0.0 2.4 1.9 2.0 1.9 1.0 2.1 1.9 2.4 2.0 2.5 1.4 0.5 2.3 1.9 1.5 -1.9
Primary Biliary Cirrhosis 0.2 0.3 1.0 0.7 -0.1 0.0 0.9 0.2 -0.3 -0.2 1.0 0.4 0.3 0.6 -0.6 0.3 0.7 0.9 -0.3 0.3 0.0 -1.0 0.4 0.1 0.0 0.5
Rheumatoid Arthritis 0.2 0.3 1.2 0.3 -0.4 0.0 -0.9 -0.5 -0.7 -0.8 0.7 -0.4 -0.5 -0.5 -0.5 -0.3 -0.5 -0.4 -1.1 -0.5 -0.3 0.1 -0.8 -0.6 -0.1 0.4
Schizophrenia 0.7 1.5 5.4 -1.9 1.4 0.2 1.1 0.1 0.6 0.7 1.6 0.9 -0.2 -0.3 1.6 0.8 0.4 -0.9 0.3 0.6 2.3 1.3 0.4 1.5 2.0 -2.0
Triglycerides 0.5 0.8 3.7 -1.5 -0.3 0.1 0.7 -0.8 -0.4 1.0 0.0 -0.1 -1.3 -1.4 1.4 -0.5 -0.8 -1.1 0.5 -0.2 0.3 0.3 -0.9 -0.7 1.2 -1.9
Type 2 Diabetes (T2D) 2.8 3.3 6.5 0.5 -2.1 -1.2 -1.5 -2.0 -2.3 -2.3 -2.1 -2.1 -1.9 -1.9 -0.8 -2.2 -2.5 -1.6 -1.0 -2.2 -1.1 -1.5 -2.4 -2.4 -1.1 -0.6
Ulcerative Colitis 0.3 0.4 1.2 -1.0 0.0 -1.0 -0.5 -0.6 -0.4 -0.7 -0.2 0.3 -0.4 -0.3 0.2 -0.1 -0.3 -1.1 -1.0 1.1 -0.6 -0.9 0.1 -0.4 0.3 -0.6
Blood Eosinophil Count 0.1 1.1 3.0 0.5 1.1 -0.6 1.7 0.8 1.4 1.0 1.1 0.5 1.2 1.2 -1.0 1.1 1.1 -0.9 -0.0 0.8 1.0 0.9 1.0 1.7 -0.5 1.0
Blood Platelet Count 1.6 18.4 53.3 7.3 2.7 -0.7 2.3 5.2 4.1 1.2 4.5 3.6 5.4 6.2 -6.0 4.3 5.6 2.1 2.0 3.1 2.6 1.6 5.4 4.2 -3.1 6.3
Blood Red Count 3.2 31.6 173.8 -13.2 0.4 4.6 -2.2 -3.4 -1.7 -0.2 -0.2 1.1 -6.7 -7.2 11.8 -1.3 -3.3 -2.4 0.2 -0.2 2.0 4.0 -4.1 -1.0 8.9 -11.8
Blood White Count 4.5 32.7 110.2 -9.8 5.6 8.1 3.5 3.1 3.8 1.9 4.9 5.6 0.6 0.0 10.5 5.0 3.3 3.4 3.3 4.9 7.0 5.7 2.4 4.7 9.8 -8.3
Heel T-Score 0.1 0.7 2.8 -0.5 0.6 0.8 0.1 -0.1 0.7 -0.0 -0.6 1.7 -0.3 0.6 -0.0 0.6 1.0 -1.0 0.2 1.3 0.3 1.5 1.2 1.3 0.2 0.2
BMI 1.3 7.7 15.0 1.2 2.8 3.1 3.9 3.7 3.5 1.5 2.4 2.6 3.3 3.5 -0.4 3.4 3.5 2.1 1.6 1.7 3.5 2.7 3.4 3.6 0.3 1.8
Height 6.4 126.5 320.4 10.3 -12.5 -11.8 -9.7 -8.5 -12.3 -7.6 -10.7 -16.6 -3.1 -5.4 -11.9 -13.0 -10.6 0.1 -6.6 -11.2 -16.7 -17.9 -9.6 -15.1 -10.9 8.4
Waist Hip Ratio (WHR) 1.8 8.1 24.1 -4.0 3.5 4.2 0.3 1.7 2.4 1.0 2.1 2.5 1.8 1.0 4.9 2.5 1.6 3.1 4.4 3.6 1.7 1.3 1.9 1.4 4.5 -3.3
Systolic Blood Pressure 3.2 16.3 40.1 1.3 4.6 2.2 2.8 4.9 4.8 0.1 3.7 4.8 4.6 4.9 1.2 5.1 5.5 3.9 6.3 4.6 4.1 2.9 5.0 5.0 1.4 -0.2
Smoking Status 0.6 1.4 8.3 -2.1 0.6 2.2 1.3 -0.3 0.1 0.2 0.2 -0.1 -0.4 -0.8 2.9 0.0 -0.5 1.1 0.1 0.2 1.4 0.0 -0.4 0.5 0.9 -2.7
Allergy or Eczema 0.3 0.9 3.1 0.9 -0.9 -1.2 -0.2 -1.0 -1.1 0.8 -0.5 -1.8 -0.0 -0.5 -0.6 -1.2 -1.2 0.3 -0.7 -1.1 -0.5 -1.5 -1.0 -1.2 -0.9 0.3
Cardiovascular Disease 0.5 1.6 6.5 0.2 1.1 0.2 1.5 1.6 1.0 -0.6 2.5 0.2 1.6 1.3 0.2 1.4 1.6 2.0 2.0 0.5 1.1 -0.2 0.9 1.2 1.5 -0.1
Hypothyroidism (self reported) 0.3 0.6 2.5 -1.1 -0.5 -0.7 -0.7 -0.7 -0.4 1.1 0.5 0.1 -1.4 -1.2 0.6 -0.5 -0.8 -1.6 -0.7 -0.5 -0.6 0.5 -0.5 -0.4 0.5 -0.2
Respiratory disease 1.3 2.8 7.3 2.0 1.5 0.5 1.4 2.1 1.7 0.8 1.1 1.3 2.7 2.7 -1.4 1.9 2.1 1.4 1.7 1.4 1.5 0.1 2.2 1.8 -0.4 1.6
Type 2 Diabetes (T2D) 0.4 0.8 2.0 1.1 -0.1 1.4 0.1 1.0 1.1 -1.4 -0.6 0.2 0.8 1.0 -0.7 0.4 0.8 1.2 0.8 -0.3 -0.3 0.8 0.8 1.0 -0.5 1.4
Lung FEV1/FVC ratio 0.2 1.2 5.1 1.4 0.1 -2.2 0.6 0.6 -0.1 0.3 -0.1 0.4 1.0 1.4 -2.3 0.5 0.7 -0.7 -0.6 0.7 -1.1 -1.3 1.0 -0.0 -0.7 2.2
Lung FVC 6.6 34.5 58.4 2.6 -7.4 -6.5 -3.6 -6.2 -7.1 -2.6 -6.0 -7.5 -5.3 -5.5 -4.5 -7.4 -6.6 -3.7 -5.1 -7.6 -6.1 -7.1 -6.7 -7.5 -4.7 2.5
Neuroticism 4.6 11.2 26.9 -4.5 4.1 4.8 1.4 2.4 2.6 0.6 3.0 3.6 2.1 1.6 5.2 3.4 2.2 2.7 3.0 4.5 3.0 1.5 2.8 2.5 4.7 -5.1
Chronotype (morning person) 1.6 3.7 21.0 -4.6 1.3 2.2 -0.7 -0.1 0.9 -0.4 -0.7 2.3 -1.0 -1.2 4.0 0.8 -0.3 -1.0 0.9 0.7 0.2 1.9 0.4 0.2 3.8 -3.4
Hair Pigment 0.1 2.8 12.0 -3.5 1.2 2.1 0.1 -0.6 0.2 -0.5 0.7 1.7 -1.3 -1.1 3.1 0.8 -0.1 -1.2 -0.3 0.7 1.3 2.6 -0.3 1.2 2.5 -3.1
Tanning 0.3 4.0 9.4 -1.7 2.3 1.9 1.2 2.7 2.5 -0.2 1.5 3.1 1.4 1.5 1.9 2.4 2.3 0.7 1.6 2.2 2.7 2.1 2.4 2.5 1.4 -0.6
Hand grip strength (left) 2.0 5.3 17.7 -3.9 1.7 3.6 -1.6 0.7 1.9 3.1 0.4 3.1 -0.3 -0.0 4.2 1.6 0.5 0.5 0.2 2.5 0.5 3.5 1.0 1.6 2.4 -3.9
Number of treatments/medications taken 0.3 0.6 3.1 0.4 -0.4 -1.3 0.0 -0.1 -0.2 -1.1 -0.4 0.0 -0.7 -0.2 -1.2 -0.2 0.0 -1.8 -1.4 -0.3 -0.0 -0.1 0.0 0.1 -1.3 1.1
Average weekly spirits intake 3.8 4.7 10.3 -1.0 2.4 1.5 2.2 2.1 2.3 0.2 2.1 3.2 1.8 2.2 1.5 2.7 2.7 2.3 2.5 2.4 2.7 1.8 2.5 2.4 2.2 -0.5
Sensitivity / hurt feelings 0.5 0.9 5.8 -1.2 -0.8 -1.1 1.0 -0.9 -0.4 -2.4 -0.5 -0.8 -0.8 -1.1 0.9 -0.7 -0.7 -0.2 -0.0 -1.0 0.0 -0.2 -1.1 -1.0 1.0 -0.5
Frequency of depressed mood in last 2 weeks 7.0 9.9 22.3 3.8 -3.5 -4.2 -0.7 -2.4 -2.6 -2.0 -2.9 -3.4 -1.6 -1.4 -4.7 -3.1 -2.1 -2.9 -3.7 -3.6 -3.0 -2.9 -2.5 -3.0 -3.9 4.7
Hearing difficulty/problems: Yes 1.1 1.7 5.7 1.4 -1.1 -1.7 -2.4 -0.9 -1.1 -1.0 -1.7 -1.4 -0.3 -0.5 -1.4 -1.0 -1.0 -1.0 -1.4 -0.7 -2.1 -1.3 -0.9 -1.2 -1.6 1.0
Relative age of first facial hair 0.3 0.7 3.8 0.5 0.2 -1.2 -0.2 0.3 -0.2 0.8 0.1 0.0 1.1 0.9 -0.3 0.1 -0.0 1.3 0.3 0.3 -1.9 -1.5 0.7 -0.3 -0.4 1.3
Other serious medical condition/disability diagnosed by doctor 2.2 2.9 7.5 1.6 1.8 -0.0 1.4 2.2 2.3 0.3 1.5 1.2 2.7 2.6 -1.3 2.2 2.2 1.4 0.9 2.3 1.4 1.3 2.1 1.6 -0.5 0.7
Ever used hormone-replacement therapy (HRT) 2.4 3.1 11.4 0.4 1.7 0.5 3.4 1.9 1.3 -0.3 2.9 1.8 1.7 2.1 -0.3 2.1 2.3 1.1 0.0 1.7 2.2 0.9 2.1 2.3 0.7 1.1
Ever had hysterectomy (womb removed) 1.5 1.7 6.7 -0.1 1.8 1.0 1.9 0.5 1.3 -1.4 2.6 1.3 0.9 0.9 0.9 1.6 1.0 -0.1 0.9 1.6 2.1 0.8 1.1 1.8 0.2 -0.5
Systolic blood pressure, automated reading 5.9 17.6 38.1 -0.3 -4.6 -3.0 -2.8 -5.2 -4.9 -0.9 -4.2 -4.8 -4.6 -4.8 -1.8 -5.1 -5.2 -4.1 -6.2 -5.0 -4.5 -3.7 -5.2 -5.1 -2.0 1.3
Eye problems/disorders: Diabetes related eye disease 3.6 3.9 9.1 -3.0 2.5 3.0 1.9 1.1 1.4 -0.5 2.2 2.0 0.7 0.4 3.0 1.9 1.3 0.3 1.4 2.2 2.9 1.6 1.2 1.8 2.1 -2.8
Angina 0.6 0.7 4.3 0.3 -0.6 -0.4 -0.9 -0.8 -1.2 0.2 -0.8 -0.4 -0.3 -0.1 0.4 -0.7 -0.5 1.8 0.1 -0.6 -1.4 -2.1 -0.4 -1.1 -0.5 -0.1
Medication for hormone replacement therapy 0.8 0.9 2.9 1.6 0.2 -0.1 0.5 0.9 0.5 -0.8 1.2 1.1 0.9 1.3 -1.1 0.9 1.2 1.1 -0.3 0.3 -0.1 0.8 1.1 1.2 -0.9 1.7
Vitamin and mineral supplements 0.2 0.3 1.1 -0.7 0.3 0.8 0.1 -0.6 -0.3 0.5 0.5 -0.4 0.4 0.1 1.0 -0.1 -0.4 0.9 -0.7 0.4 -0.4 -0.2 -0.3 -0.5 0.5 -1.0
Supplements: Zinc 0.9 1.0 3.8 -0.3 0.8 1.1 1.1 1.4 1.1 -0.3 0.9 0.6 0.6 0.7 0.2 1.1 1.1 0.5 1.2 -0.0 1.7 1.5 0.9 1.9 0.9 0.6
Medication: Co-codamol 1.3 1.5 5.5 1.6 -1.1 -1.9 -0.3 -0.7 -1.0 -0.2 -1.0 -1.8 -0.5 -0.5 -2.3 -1.2 -0.7 -1.9 -0.8 -1.1 -0.6 -1.1 -1.0 -1.1 -1.3 1.2
Medication: Metformin 0.4 0.6 2.3 -0.0 -0.3 -0.7 -0.5 -1.3 -1.2 -0.4 0.2 -0.7 -0.5 -0.7 -0.2 -0.6 -0.7 -0.7 -0.8 -0.3 -0.1 -1.5 -1.0 -1.5 0.2 -0.6
Diabetes (father) 0.2 0.2 1.3 -0.2 0.2 -0.3 0.3 0.5 -0.0 1.1 0.5 0.2 0.5 0.4 0.0 0.3 0.2 -0.1 -0.4 0.6 -0.1 0.1 0.4 -0.5 0.8 -0.2
Diabetes (mother) 0.7 0.9 2.3 -0.6 -0.6 -0.4 -1.5 -1.2 -1.1 0.4 -1.3 -0.8 -1.1 -1.3 0.8 -1.0 -1.4 -1.0 -0.9 -0.3 -0.9 -0.2 -1.2 -1.4 -0.4 -0.5
Severe depression (siblings) 1.5 1.7 4.0 0.3 -1.9 -0.6 -1.2 -1.6 -0.8 -2.0 -1.2 -1.2 -1.8 -1.6 -0.5 -1.7 -1.1 -1.2 -1.3 -0.9 -1.1 0.2 -1.7 -1.0 -1.1 -1.4
Pack years adult smoking proportion 0.5 0.8 6.6 0.8 -0.4 -2.6 -0.7 -0.4 -0.8 -0.9 0.8 -0.5 0.4 0.4 -0.9 -0.3 -0.2 0.9 -0.2 0.7 -0.7 -1.8 0.1 -0.8 -0.5 -0.3
Impedance of leg (right) 1.9 9.5 54.8 6.8 -1.1 -3.0 0.9 1.5 0.3 0.4 -1.5 -1.9 2.6 2.7 -6.6 -0.3 0.6 0.1 -0.8 -1.9 -1.6 -2.3 1.0 -0.5 -5.1 7.4
Leg fat-free mass (left) 2.7 14.5 43.2 -6.6 3.4 4.0 0.8 0.5 2.7 1.1 2.6 5.2 -1.5 -0.8 6.5 3.0 1.8 -1.6 1.6 3.7 4.2 6.2 1.5 3.6 5.3 -6.6
Trunk fat percentage 2.8 11.3 20.2 1.3 -3.8 -4.5 -2.8 -3.9 -3.6 -3.0 -3.1 -3.2 -3.6 -3.2 -2.8 -4.2 -3.5 -3.9 -3.8 -3.4 -3.5 -3.1 -3.3 -3.5 -3.0 1.2
Hand grip strength (right) 1.5 4.0 12.9 -3.1 1.6 3.5 -0.9 0.8 1.9 2.2 0.7 2.8 -0.2 0.1 3.4 1.6 0.6 0.4 0.5 2.1 0.4 3.6 0.9 1.6 1.9 -3.3
Townsend deprivation index at recruitment 0.2 0.3 2.1 0.1 -0.6 -0.7 -0.8 -0.2 -0.2 -1.4 -0.2 0.2 -0.5 -0.2 -0.1 -0.5 -0.6 0.0 -0.7 0.3 -0.9 0.5 0.3 -0.3 -0.6 -0.5
Current tobacco smoking 2.1 3.5 17.4 3.7 -0.9 -2.3 -0.2 0.8 -0.2 -2.8 0.2 -1.0 1.6 1.8 -4.2 -0.0 0.7 0.2 -0.5 0.1 -1.2 -2.0 0.6 -0.6 -2.9 3.5
Average weekly fortified wine intake 1.6 1.9 10.4 -3.2 0.9 1.2 -0.8 -0.8 0.4 1.2 -0.4 0.9 -1.4 -1.6 2.9 0.2 -0.4 -1.4 0.0 0.4 0.2 1.4 -0.5 0.3 2.1 -2.3
Maternal smoking around birth 2.1 3.0 11.3 1.3 -1.9 -3.4 -2.5 -1.8 -1.6 0.2 -1.1 -1.7 -1.3 -1.2 -1.9 -1.8 -1.6 -1.7 -2.3 -1.4 -1.9 -1.4 -1.8 -1.9 -1.5 0.4
Fed-up feelings 5.7 10.6 35.4 5.2 -3.4 -4.8 -0.3 -2.2 -2.3 -2.1 -2.5 -3.1 -1.5 -0.8 -6.0 -3.0 -1.8 -3.2 -2.6 -3.3 -2.8 -2.7 -1.8 -2.0 -5.4 4.8
Frequency of unenthusiasm / disinterest in last 2 weeks 6.6 8.9 20.3 3.3 -3.4 -4.0 -1.1 -2.2 -2.8 -1.7 -2.6 -3.8 -1.3 -1.3 -4.5 -3.0 -2.1 -2.2 -3.5 -3.3 -2.8 -3.0 -2.5 -2.7 -3.7 4.3
Relative age voice broke 0.9 1.4 4.8 1.0 -0.8 -2.0 -1.5 -0.3 -0.9 -0.3 -0.5 -0.8 -0.1 -0.2 -1.3 -0.9 -0.8 0.1 -1.1 -0.7 -2.2 -2.1 -0.3 -1.4 -1.1 2.2
Taking other prescription medications 0.2 0.3 2.3 -0.6 0.4 -0.4 0.1 -0.5 0.2 -1.5 0.1 0.2 -0.3 -0.3 0.6 0.1 -0.2 -0.4 -0.4 1.0 0.3 -0.0 -0.1 -0.3 -0.3 -1.2
Age when periods started (menarche) 0.3 0.8 2.6 -0.8 1.4 0.8 -0.3 0.6 0.8 1.6 1.0 1.1 1.0 0.9 1.3 0.8 0.2 0.8 0.2 1.6 -0.4 -0.3 1.2 0.1 0.9 0.5
Bilateral oophorectomy (both ovaries removed) 1.7 2.0 8.2 -0.8 1.8 0.1 2.6 0.7 0.8 -1.1 2.9 1.6 0.7 0.8 0.9 1.6 1.4 0.0 0.4 1.8 1.9 1.1 1.1 1.2 1.7 -1.5
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.5 2.0 -1.2 0.1 -0.5 0.0 -0.6 -0.5 0.6 1.4 -0.1 -0.4 -0.6 1.0 -0.1 -0.4 0.5 -0.8 0.0 -0.5 -0.6 -0.5 -0.5 1.3 -1.0
Tinnitus: Yes, but not now, but have in the past 3.3 3.5 6.2 -0.4 -1.6 -1.7 -1.7 -2.2 -2.4 -0.5 -2.5 -1.9 -2.1 -2.1 -0.2 -2.3 -2.5 -1.8 -2.2 -1.4 -2.0 -2.1 -2.2 -2.3 -1.1 -0.8
Qualifications: CSEs or equivalent 1.0 1.3 3.8 1.6 -0.6 -1.9 -1.0 -0.6 -1.0 0.3 -1.4 -1.5 0.2 -0.0 -1.5 -1.0 -0.9 0.3 -0.9 -0.6 -1.6 -1.6 -0.6 -1.3 -1.4 1.2
Serious illness, injury or assault to yourself 2.1 2.5 6.0 -0.4 2.1 1.7 1.1 1.8 2.4 0.6 1.8 1.7 1.3 1.2 0.8 1.8 1.5 0.4 1.6 2.3 2.5 2.2 1.7 1.5 0.3 -1.2
High blood pressure 0.8 2.1 10.2 -0.8 -1.0 -0.4 -1.1 -2.0 -1.1 0.5 -2.1 -0.3 -2.0 -1.7 -0.1 -1.3 -1.5 -3.2 -3.1 -0.6 -0.5 0.5 -1.5 -1.1 -0.9 0.5
Hayfever, allergic rhinitis or eczema 0.4 0.8 2.3 -1.1 0.8 1.3 -0.3 0.7 0.7 -0.5 0.4 1.5 -0.1 0.2 1.2 0.9 0.7 0.1 1.0 1.2 0.4 1.2 0.7 0.9 0.7 -1.4
Multivitamins +/- minerals 0.2 0.3 0.7 -0.2 0.2 -0.4 0.5 0.5 0.4 -0.6 -0.0 0.9 -0.3 0.0 -0.2 0.5 0.6 -0.8 0.8 -0.1 0.7 0.3 0.4 0.7 0.7 0.7
Stomach or abdominal pain in last month 0.7 0.8 4.9 -1.6 0.6 0.6 -0.3 0.2 0.6 -0.6 -1.0 0.6 -0.0 -0.3 1.7 0.4 -0.0 -0.5 0.9 0.8 0.6 1.3 -0.1 0.3 1.4 -2.2
Supplements: Glucosamine 0.4 0.5 1.5 -0.8 -0.1 0.0 1.2 -0.3 -0.3 0.4 -0.9 -0.7 -0.8 -1.0 0.1 -0.3 -0.6 -1.0 -0.7 -1.2 0.4 0.8 -0.8 0.0 0.9 -0.0
Diverticular disease/diverticulitis (self-reported) 0.2 0.3 1.8 -0.4 0.1 -0.3 0.3 -0.5 -0.0 -0.2 0.1 -0.2 -0.6 -0.6 -0.0 -0.2 -0.6 -1.3 -1.3 -0.4 0.6 0.5 -0.2 0.1 0.1 0.4
Medication: Atenolol 0.4 0.5 4.4 -0.8 0.1 0.6 0.1 -0.6 0.4 0.6 -0.2 0.6 -0.8 -0.5 0.8 -0.1 0.2 -0.9 -1.0 -0.2 0.2 2.1 -0.3 0.3 0.3 -0.8
Medication: Levothyroxine sodium 0.2 0.3 1.4 -0.7 0.1 0.8 -0.9 -0.6 0.3 -1.0 -1.2 0.4 -0.3 -0.2 0.8 0.0 0.1 0.1 -0.2 0.4 -0.1 0.6 -0.3 -0.1 0.5 -1.1
Sitting height 14.7 106.0 216.1 -9.8 11.6 10.9 9.7 8.0 10.6 5.1 10.2 13.9 4.4 5.5 11.7 11.8 9.5 2.7 8.7 10.9 14.7 14.0 8.7 13.0 11.3 -9.7
Chronic bronchitis/emphysema (father) 0.6 0.8 1.7 -1.0 0.9 0.5 1.0 0.4 1.3 -0.1 1.1 0.8 0.2 0.2 1.3 0.7 0.3 0.1 0.8 1.1 1.3 1.0 0.7 1.2 0.6 -1.3
High blood pressure (mother) 0.3 0.4 2.0 -0.5 0.3 1.4 -1.2 0.3 0.8 0.5 -0.0 0.3 0.1 0.2 0.8 0.3 0.3 0.2 -0.1 -0.0 0.4 1.4 0.0 1.1 0.1 -0.5
Body mass index (BMI) 1.5 6.6 13.0 -1.2 -2.4 -2.6 -3.1 -3.6 -3.0 -2.3 -2.2 -2.1 -3.4 -3.4 0.3 -3.1 -3.1 -2.8 -2.0 -1.7 -2.9 -1.9 -2.9 -2.9 -0.5 -1.7
Impedance of leg (left) 1.9 9.6 50.6 6.7 -1.6 -3.2 0.7 0.9 -0.3 -0.6 -1.8 -2.3 2.1 2.2 -6.6 -0.9 0.0 -0.1 -1.4 -2.3 -1.9 -3.1 0.4 -1.0 -5.4 7.1
Leg predicted mass (left) 2.6 14.1 43.0 -6.5 3.3 4.0 0.7 0.5 2.6 1.1 2.5 5.1 -1.6 -0.8 6.5 2.9 1.7 -1.6 1.6 3.6 4.2 6.1 1.4 3.6 5.3 -6.6
Trunk fat mass 0.9 3.8 14.3 -1.1 -1.7 -2.4 -1.9 -2.9 -1.8 -1.7 -1.5 -0.5 -3.3 -2.7 -0.1 -2.1 -2.1 -3.8 -2.4 -1.3 -1.3 -0.3 -2.0 -1.4 -0.7 -1.1
Waist circumference 1.3 4.7 15.8 -0.8 -2.2 -2.8 -2.2 -3.0 -2.3 -1.8 -2.0 -1.0 -3.4 -2.8 -0.5 -2.3 -2.2 -4.0 -2.6 -1.8 -1.6 -0.5 -2.3 -1.8 -0.7 -0.8
Number of incorrect matches in round 3.8 6.3 12.5 -1.1 -3.0 -1.4 -2.2 -3.4 -3.3 -1.0 -1.9 -2.5 -3.5 -3.4 0.6 -3.2 -3.0 -1.8 -3.4 -2.2 -1.5 -2.3 -3.5 -3.2 -0.7 -1.5
Past tobacco smoking 0.4 0.7 2.3 0.3 -0.4 1.0 0.9 -0.3 -0.7 -1.5 0.4 -1.2 0.1 -0.2 0.2 -0.6 -0.6 1.3 -0.7 0.1 0.6 -1.4 -0.6 -0.3 -1.5 -1.1
Alcohol usually taken with meals 0.2 0.3 1.4 -1.2 -0.3 1.0 -0.1 -0.0 -0.3 -0.2 -0.9 -0.5 -0.0 -0.4 0.7 -0.1 0.0 0.4 -0.3 -0.5 -0.2 0.6 -0.6 -0.5 0.7 -0.9
Nervous feelings 1.6 3.1 6.0 -1.0 -1.9 -1.6 -2.0 -2.1 -2.0 -0.4 -2.5 -1.6 -2.3 -2.3 0.2 -2.1 -2.4 -1.9 -1.8 -2.0 -1.1 -1.2 -2.2 -2.0 -0.1 0.3
Frequency of tenseness / restlessness in last 2 weeks 3.1 5.0 11.7 2.6 -2.5 -3.4 -0.8 -1.7 -2.1 -1.2 -1.5 -2.4 -1.7 -1.4 -3.1 -2.4 -1.8 -2.7 -2.7 -2.8 -1.2 -0.9 -1.9 -1.7 -3.1 2.7
Hearing difficulty/problems with background noise 3.5 5.7 13.8 0.7 -2.6 -2.1 -3.4 -2.1 -2.8 -2.7 -3.0 -2.5 -1.5 -1.5 -1.7 -2.4 -2.1 -1.1 -3.2 -1.2 -3.7 -2.9 -2.3 -3.3 -2.1 0.9
Hair/balding pattern: Pattern 2 0.8 1.1 2.9 -0.9 -1.3 -0.0 -0.6 -1.0 -0.8 -0.3 -1.7 -1.2 -1.4 -1.4 0.2 -1.3 -1.1 -0.6 -0.8 -1.3 -1.4 -0.5 -1.4 -1.0 -0.3 -0.8
Had menopause 0.2 0.2 0.9 0.8 -0.1 0.5 0.9 -0.4 -0.2 -0.3 0.7 0.3 0.1 0.4 -0.5 0.2 0.7 0.7 -0.9 0.0 -0.4 -0.6 0.0 -0.1 -0.1 0.6
Had other major operations 2.4 2.9 5.5 -0.7 2.2 1.6 1.1 1.7 2.3 0.4 1.1 2.3 1.4 1.4 1.3 2.3 1.9 0.5 1.9 2.2 2.4 2.3 1.7 2.1 0.6 -1.4
Forced vital capacity (FVC) 7.1 28.0 69.3 -3.2 6.1 6.0 3.7 5.2 6.4 3.2 4.9 7.3 3.6 4.3 4.4 6.6 5.8 2.3 2.9 5.9 6.4 8.3 5.4 7.4 4.1 -2.3
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.5 3.6 -0.6 -0.1 -0.3 0.0 -0.4 -0.4 0.6 1.9 -0.3 -0.2 -0.5 0.7 -0.3 -0.4 0.7 -0.9 -0.2 -0.4 -0.6 -0.5 -0.9 0.9 -0.9
Ever unenthusiastic/disinterested for a whole week 2.0 2.5 4.4 1.2 -2.0 -1.9 -1.2 -1.4 -1.3 -1.1 -1.5 -1.9 -1.0 -1.0 -1.9 -1.9 -1.5 -0.6 -1.7 -1.7 -1.9 -2.1 -1.5 -1.8 -1.9 1.3
Qualifications: None of the above 0.6 1.3 7.7 1.7 -1.2 -1.8 -1.3 -0.4 -0.9 -0.2 -0.2 -0.9 0.2 0.4 -1.4 -0.9 -0.3 1.5 -0.4 -0.3 -1.1 -2.8 0.0 -1.0 -1.4 1.2
Financial difficulties in last 2 years 0.8 1.1 4.2 1.3 -1.2 -2.0 -1.0 -0.2 -1.2 -0.6 -1.3 -1.0 -0.1 -0.0 -1.1 -0.9 -0.8 0.1 -0.9 -0.2 -1.2 -1.4 -0.5 -0.7 -1.9 0.8
Mouth/teeth dental problems 0.4 0.6 2.7 -0.4 -0.7 0.6 -0.9 -0.4 -0.7 -0.1 -0.9 -1.6 0.2 -0.6 0.1 -0.8 -0.9 0.9 -0.3 -0.7 -0.9 -0.7 -1.2 -1.3 -0.4 -0.9
Heart attack 1.7 2.1 4.1 -0.9 2.0 1.4 1.3 1.1 1.6 1.0 1.7 1.2 1.1 0.9 1.9 1.5 1.0 1.3 2.0 1.5 2.0 0.9 1.3 1.6 1.3 -2.0
Allergy 0.3 0.6 2.8 1.0 -0.5 -1.2 -0.2 -0.4 -0.5 1.0 -0.9 -1.1 0.2 0.0 -1.3 -0.6 -0.5 -0.8 -0.7 -1.0 -0.6 -0.9 -0.2 -0.3 -0.5 1.7
Pain all over the body in last month 1.2 1.3 5.8 1.8 -1.3 -0.3 -0.2 -0.5 -0.8 -2.0 -1.1 -1.4 -0.1 -0.0 -1.8 -1.0 -0.4 0.2 -1.2 -0.7 -0.9 -1.1 -0.8 -0.8 -2.4 1.0
Diabetes (self-reported) 0.5 0.7 2.2 -0.4 -0.0 -1.2 -0.4 -1.3 -1.0 0.1 0.6 -0.1 -1.0 -0.9 0.2 -0.6 -0.8 -1.5 -1.1 -0.1 0.1 -1.3 -0.8 -1.1 -0.2 -1.3
Hayfever/allergic rhinitis (self-reported) 0.2 0.3 1.6 -0.2 -0.1 -0.1 -0.3 -0.3 -0.0 0.7 -0.4 0.3 -0.9 -0.5 0.2 -0.2 -0.3 -1.3 -0.9 -0.1 -0.4 0.9 -0.1 0.4 -0.3 -0.9
Medication: Ramipril 0.7 0.8 3.3 -0.7 -0.0 -0.2 -1.8 -1.3 -0.3 0.7 -1.4 0.0 -1.2 -1.0 0.6 -0.5 -1.0 -1.8 -1.2 0.2 -0.9 0.1 -0.6 -0.6 -0.1 -0.9
Medication: Simvastatin 0.3 0.5 2.1 1.0 0.3 -0.6 0.6 0.3 0.3 -0.7 0.5 0.5 0.8 1.0 -0.9 0.5 0.8 -0.1 -0.3 0.2 0.6 -0.0 0.8 0.8 -1.2 1.5
Fluid intelligence score 1.3 2.7 12.8 -0.6 1.7 1.3 1.1 0.9 1.5 3.1 2.0 2.3 0.2 0.6 1.2 1.6 1.4 -0.4 1.5 1.4 1.9 3.6 1.3 1.7 1.6 -0.4
Illnesses of siblings 2.3 3.2 8.9 0.9 1.2 2.3 1.6 2.8 1.3 -0.6 0.7 1.5 2.8 2.6 -0.4 2.1 2.8 3.0 1.3 0.6 1.7 1.7 1.9 1.7 0.7 0.7
Neuroticism score 5.1 10.9 25.5 4.0 -4.1 -5.0 -1.3 -2.6 -2.8 -1.6 -3.1 -3.7 -2.1 -1.8 -4.9 -3.4 -2.4 -2.8 -2.9 -4.5 -2.9 -2.1 -3.0 -2.6 -4.3 4.4
Weight 0.9 4.4 16.9 -4.1 1.3 1.0 -0.4 -1.0 0.8 -0.2 0.7 2.9 -2.3 -1.5 3.6 0.9 0.1 -2.6 -0.2 1.7 1.7 3.5 0.1 1.5 2.6 -4.0
Impedance of arm (right) 1.5 7.1 23.6 3.7 -2.9 -2.8 -1.0 -0.8 -1.6 -1.0 -2.3 -3.4 -0.2 -0.5 -4.9 -2.5 -1.5 -1.1 -2.5 -3.2 -2.5 -3.1 -1.4 -2.5 -3.8 4.7
Arm fat percentage (right) 2.6 10.6 17.1 0.3 -3.5 -3.9 -3.7 -4.1 -3.7 -2.5 -2.8 -3.4 -3.6 -3.5 -1.7 -4.1 -3.8 -3.3 -3.1 -2.9 -4.0 -3.3 -3.5 -3.9 -2.1 0.2
Trunk fat-free mass 6.7 39.2 102.0 -7.7 7.0 7.0 3.0 3.4 6.2 4.1 5.3 9.2 0.8 1.9 8.8 6.7 4.8 -0.0 3.9 7.0 7.4 10.1 4.5 7.2 7.3 -7.7
Hip circumference 0.7 3.3 12.2 -3.5 -0.3 -0.0 -1.7 -2.3 -0.8 -0.9 -0.6 0.7 -3.1 -2.7 2.7 -1.0 -1.6 -2.9 -0.8 0.0 -0.3 1.2 -1.4 -0.8 1.8 -3.2
Time employed in main current job 0.7 0.8 3.6 -1.3 -1.0 0.5 0.2 -0.9 -1.0 0.3 -0.6 -0.6 -1.4 -1.3 1.0 -1.1 -0.8 0.2 -0.7 -0.8 -0.0 -0.3 -1.1 -0.7 0.3 -1.9
Alcohol intake versus 10 years previously 3.8 5.7 14.8 2.3 -2.3 -3.9 -0.5 -1.7 -2.0 -2.2 -2.3 -3.1 -1.0 -1.2 -3.6 -2.4 -1.9 -2.5 -1.7 -2.2 -1.9 -3.4 -1.7 -2.4 -2.9 3.0
Father’s age at death 0.7 0.9 5.7 -2.4 0.8 1.6 0.2 -0.3 0.1 -0.1 0.4 0.1 -0.0 -0.5 1.8 0.5 0.1 0.5 0.1 -0.1 0.4 0.6 -0.3 0.4 2.3 -1.3
Worrier / anxious feelings 1.1 2.2 6.8 0.6 -1.8 -1.9 0.3 -1.7 -1.8 -0.1 -1.3 -2.0 -1.6 -1.5 -1.2 -1.6 -1.2 -1.8 -1.6 -2.6 -0.4 0.3 -2.2 -1.0 -0.8 1.3
Frequency of tiredness / lethargy in last 2 weeks 3.4 5.6 21.6 3.9 -2.3 -3.5 -0.4 -1.0 -1.5 -2.1 -1.6 -2.6 -0.2 -0.2 -4.7 -1.9 -0.9 -2.4 -2.4 -2.0 -2.0 -1.8 -1.2 -1.6 -3.4 3.9
Falls in the last year 0.5 0.6 3.0 0.9 -0.7 -1.7 -0.1 -0.5 -0.3 -0.9 -0.9 -1.1 0.0 -0.2 -1.7 -0.6 -0.1 -0.5 -0.5 -0.5 -0.5 -0.4 -0.7 -0.7 -1.2 0.2
Hair/balding pattern: Pattern 3 1.1 1.6 4.9 2.1 -1.0 -1.8 0.1 -0.5 -1.0 -1.6 -0.3 -1.6 0.2 0.1 -2.0 -0.9 -0.7 -0.6 -1.5 -0.7 -0.7 -2.2 -0.4 -0.6 -2.0 1.8
Number of live births 0.3 0.4 2.0 -1.4 -0.1 -0.1 -0.2 -0.7 -0.8 0.8 0.1 -0.4 -0.8 -0.8 1.2 -0.5 -0.7 0.3 -0.4 -0.2 0.2 -0.2 -0.7 -0.1 0.8 -1.2
Forced expiratory volume in 1-second (FEV1) 6.6 22.8 59.1 -3.5 5.4 6.4 2.8 4.4 5.7 2.5 4.2 6.3 2.8 3.3 4.8 5.7 4.8 2.2 2.8 5.2 6.0 7.7 4.5 6.6 3.8 -2.9
Pulse rate 1.0 1.7 4.6 -1.7 1.8 1.4 0.2 1.1 1.1 -1.0 1.3 2.1 0.5 0.5 1.6 1.5 0.9 -0.6 0.4 2.1 1.6 1.2 1.5 1.3 1.3 -0.8
Happiness 1.2 1.4 4.8 1.7 -1.3 -1.7 -0.1 -0.5 -1.0 -1.0 -1.3 -0.7 -0.6 -0.1 -2.2 -0.9 -0.4 -1.4 -1.2 -1.8 -0.2 -0.6 -0.8 -0.4 -1.6 2.2
Noisy workplace 1.7 2.1 4.3 0.0 -1.8 -1.3 -1.4 -1.6 -1.7 -2.1 -1.7 -1.7 -1.4 -1.5 -0.5 -1.6 -1.4 -0.6 -1.5 -1.9 -1.2 -1.3 -1.8 -1.5 -1.1 1.1
Qualifications: A levels/AS levels or equivalent 2.1 4.8 11.8 -1.3 2.4 3.4 2.5 2.2 2.4 1.6 2.0 2.2 1.2 1.2 2.0 2.5 2.0 0.0 1.3 2.4 3.3 3.4 1.6 3.1 1.1 -1.7
Serious illness, injury or assault of a close relative in last 2 years 0.5 0.5 1.6 -1.1 1.1 0.5 -0.8 0.8 1.1 0.2 0.1 0.7 0.2 0.1 0.7 0.7 0.1 -0.5 0.8 1.0 0.4 0.9 0.6 1.1 0.0 -1.3
Mouth/teeth dental problems: Dentures 1.0 1.7 5.0 0.4 1.3 -0.7 1.2 1.0 1.5 1.3 2.2 2.2 0.8 1.4 0.4 1.5 1.5 0.8 1.2 1.8 1.2 0.7 2.0 1.6 0.9 0.2
Asthma 0.4 0.7 3.1 -1.7 0.0 1.6 -0.1 -0.7 -0.3 -0.5 0.2 0.2 -1.0 -1.0 1.8 -0.2 -0.3 0.3 0.2 0.2 -0.2 1.1 -0.6 -0.4 1.0 -1.8
Medication: Ibuprofen (e.g. Nurofen) 4.2 5.4 16.8 3.4 -2.0 -3.8 -1.8 -0.7 -1.9 -0.2 -1.8 -1.9 -0.6 -0.4 -4.1 -1.6 -1.4 -1.8 -2.8 -2.2 -2.5 -2.3 -0.9 -2.0 -3.1 3.8
Medication: Cholesterol lowering 0.6 0.9 3.2 0.7 -1.1 -1.7 -1.7 -0.9 -0.9 0.4 -0.9 -0.3 -0.6 -0.3 -0.6 -0.9 -0.8 -0.4 -0.7 -0.6 -1.2 -0.6 -0.5 -0.6 -1.8 1.1
Depression (self-reported) 3.2 3.9 8.5 1.4 -2.7 -2.2 -0.8 -1.1 -1.6 -1.4 -2.5 -2.5 -1.4 -1.5 -2.3 -2.3 -1.5 -1.3 -2.6 -2.9 -2.0 -1.5 -2.0 -2.2 -2.1 1.8
Medication: Lansoprazole 1.5 1.7 4.7 1.2 -1.5 -1.3 -0.7 -1.4 -1.6 -0.9 -2.2 -1.2 -0.8 -0.7 -1.2 -1.3 -1.1 -0.6 -1.9 -1.6 -1.9 -0.8 -1.3 -1.6 -1.4 0.6
Prospective memory result 4.2 5.1 10.2 0.9 -2.8 -2.3 -2.3 -2.1 -2.1 -1.0 -3.2 -3.0 -1.5 -1.8 -2.1 -2.7 -2.4 -2.1 -1.9 -2.3 -2.6 -2.9 -2.3 -2.5 -2.3 0.8
Lung cancer (father) 2.1 2.4 4.9 -0.1 -1.7 -1.2 -0.4 -2.2 -2.1 -1.1 -0.8 -1.9 -2.1 -2.1 -0.3 -2.0 -2.0 -1.6 -1.5 -1.4 -1.0 -1.5 -2.0 -1.9 -0.8 -0.6
Illnesses of mother 0.6 0.7 2.7 1.1 -0.2 -1.3 0.6 0.2 -0.5 -1.1 -0.6 -0.0 1.0 1.0 -1.5 0.2 0.4 1.2 0.3 0.1 -1.1 -1.6 0.5 -0.9 -0.4 1.0
Forced expiratory volume in 1-second (FEV1), Best measure 6.0 19.5 45.6 -2.9 5.1 5.8 2.3 4.1 5.6 3.2 3.9 5.8 2.6 3.0 4.3 5.2 4.3 1.8 2.9 5.0 5.7 6.8 4.2 6.2 3.2 -2.5
Pulse wave Arterial Stiffness index 0.6 0.7 3.0 -1.2 0.7 0.9 1.0 0.5 1.0 0.3 -0.1 1.3 0.0 0.3 1.1 0.9 0.8 0.1 0.0 0.1 0.6 1.7 0.5 1.3 1.0 -0.1
Impedance of arm (left) 1.5 7.1 25.9 4.0 -2.9 -3.0 -0.6 -0.8 -1.7 -0.8 -2.0 -3.4 -0.2 -0.3 -5.1 -2.4 -1.3 -1.1 -2.4 -3.3 -2.3 -3.0 -1.4 -2.2 -3.7 4.8
Arm fat mass (right) 0.9 4.0 11.0 -1.7 -1.6 -1.8 -2.5 -3.0 -1.9 -1.6 -1.3 -0.7 -3.3 -2.9 0.8 -2.2 -2.3 -3.1 -1.9 -1.0 -1.6 -0.4 -2.1 -1.8 -0.0 -1.9
Trunk predicted mass 6.7 38.8 100.0 -7.6 7.0 7.0 3.0 3.4 6.2 4.0 5.2 9.2 0.8 1.9 8.8 6.6 4.8 -0.1 3.9 7.0 7.3 10.0 4.5 7.2 7.2 -7.7
Standing height 5.4 54.5 148.8 -6.5 8.2 8.0 5.7 5.6 8.4 4.9 6.6 11.3 2.3 3.9 7.6 8.7 7.1 0.1 4.0 7.7 10.3 12.2 6.4 9.7 7.0 -5.6
Length of working week for main job 0.2 0.3 1.1 -0.1 -0.3 0.1 0.9 -0.3 -0.6 0.0 0.5 -0.4 -0.4 -0.1 -0.3 -0.2 -0.1 0.7 -1.0 -0.9 0.6 0.4 -0.3 0.4 -0.4 0.7
Exposure to tobacco smoke at home 0.2 0.2 0.8 0.5 -0.3 -0.9 0.4 -0.3 -0.3 -0.1 -0.1 -0.5 -0.3 -0.2 -0.6 -0.5 -0.4 -0.7 -0.3 -0.2 0.1 -0.6 -0.4 -0.3 -0.8 0.3
Breastfed as a baby 0.5 0.6 2.7 -1.6 -0.1 0.8 0.2 -0.5 -0.2 0.2 -0.2 -0.1 -0.9 -1.1 1.2 -0.4 -0.9 -0.7 -0.6 0.1 0.8 0.2 -0.7 -0.7 0.4 -1.6
Tense / ‘highly strung’ 0.7 1.2 2.9 -0.7 -1.0 -0.9 -0.5 -1.2 -1.0 1.4 -1.2 -0.9 -1.7 -1.6 0.2 -1.1 -1.3 -1.6 -0.7 -1.7 0.3 0.9 -1.5 -0.4 0.1 -0.2
Seen doctor (GP) for nerves, anxiety, tension or depression 1.3 1.9 5.7 0.5 -1.8 -0.9 -0.7 -1.1 -1.2 -2.4 -2.3 -1.0 -1.6 -1.4 -0.9 -1.5 -1.1 -1.4 -1.4 -1.8 -0.7 -0.0 -1.6 -1.5 -1.9 -0.1
Hair/balding pattern: Pattern 4 1.5 3.9 8.9 2.4 -2.2 -1.5 -2.4 -1.6 -2.1 1.1 -1.6 -2.8 -0.7 -1.0 -2.4 -2.2 -1.8 -0.3 -1.3 -2.2 -3.0 -1.8 -1.9 -2.2 -2.2 2.0
Birth weight of first child 1.3 2.4 5.8 -1.3 1.8 1.1 0.3 1.4 2.0 0.6 1.5 2.3 1.1 1.2 1.7 2.0 1.6 0.5 0.8 2.0 1.4 2.4 1.5 1.9 1.5 -1.4
Peak expiratory flow (PEF) 2.6 6.2 23.2 -3.3 2.4 3.3 0.2 1.2 2.3 2.2 2.0 3.5 -0.0 0.4 3.7 2.4 1.5 -0.3 0.7 2.6 2.7 4.8 1.4 3.0 2.8 -3.1
Pulse wave reflection index 2.0 2.4 7.2 0.6 -2.2 -1.3 -0.8 -1.7 -1.8 -0.0 -1.6 -2.0 -1.2 -1.2 -1.0 -2.0 -1.6 0.0 -1.6 -2.0 -2.7 -0.9 -1.9 -2.0 -1.4 0.4
Ever highly irritable/argumentative for 2 days 1.0 1.2 6.2 1.7 -1.4 -0.5 -0.5 -0.6 -0.7 -2.4 -0.7 -1.0 -0.4 -0.1 -2.0 -1.1 -0.3 -0.3 -0.7 -0.7 -0.6 -0.8 -0.6 -0.5 -2.5 0.3
Loud music exposure frequency 1.0 1.1 2.9 1.0 -1.3 -1.6 -1.3 -0.6 -0.6 -0.8 -1.4 -0.7 -0.9 -0.6 -1.6 -1.0 -0.8 -0.8 -0.8 -1.3 -1.2 -0.4 -0.6 -0.4 -1.7 1.2
Qualifications: O levels/GCSEs or equivalent 3.0 4.8 9.5 -0.8 2.7 2.8 2.2 2.7 2.6 1.3 2.3 2.0 2.2 1.9 1.2 2.6 2.5 1.0 1.8 2.3 3.1 2.5 2.2 2.9 1.4 -0.3
Mouth/teeth dental problems: Bleeding gums 0.2 0.3 1.9 0.4 -0.1 -0.3 0.3 -0.2 -0.1 0.9 -1.1 0.4 -0.7 -0.1 -0.3 -0.1 0.1 -1.4 0.1 -0.5 0.0 0.5 0.0 0.8 -0.4 0.6
Blood clot in the leg (DVT) 1.0 1.3 6.1 0.4 1.1 -0.3 1.8 0.9 1.1 -0.0 2.5 0.7 1.3 1.1 0.2 1.1 1.2 2.1 1.2 1.0 1.6 0.4 0.9 0.8 0.4 -0.3
Medication: Paracetamol 2.3 3.9 20.1 4.5 -0.8 -2.8 1.8 0.8 -0.3 -0.9 0.2 -1.1 1.1 1.4 -4.4 -0.2 0.7 -0.6 -0.7 -0.9 -0.1 -1.3 0.6 0.3 -3.6 3.8
Headache pain in last month 1.2 2.0 6.6 2.0 -1.4 -2.4 0.1 -0.9 -1.5 -0.5 -1.1 -1.5 -0.6 -0.4 -2.6 -1.2 -0.9 -1.8 -1.1 -1.3 -0.7 -2.3 -0.8 -1.1 -1.9 1.5
Medication for cholesterol, blood pressure or diabetes 0.6 1.0 3.5 0.1 0.8 1.5 1.0 1.4 1.0 -0.7 0.7 0.2 1.2 1.0 0.1 0.9 1.2 1.9 1.4 0.3 0.8 0.4 0.8 0.5 1.3 -0.6
Glaucoma (self-reported) 0.3 0.4 1.0 0.5 0.5 -0.5 0.7 0.6 0.4 1.0 0.7 0.9 0.3 0.5 -0.3 0.6 0.5 -0.7 0.7 -0.1 0.4 0.3 0.7 0.9 -0.0 0.9
Gout (self-reported) 0.9 1.2 3.2 0.3 1.2 1.8 1.5 0.8 1.1 -0.0 1.8 1.0 0.8 0.9 0.4 1.2 1.3 1.0 1.6 1.0 1.2 1.2 0.9 0.9 0.9 -0.4
Hypothyroidism/myxoedema (self-reported) 0.4 0.7 2.2 0.2 1.2 1.3 0.4 0.5 0.8 -0.5 -0.4 0.6 1.4 1.3 0.3 1.0 1.1 1.5 0.9 0.9 0.5 0.2 0.8 0.9 0.6 -0.6
Medication: Amlodipine 0.6 0.8 3.4 -0.2 0.9 0.9 1.1 -0.0 0.9 1.5 0.1 1.1 -0.4 0.0 0.5 0.6 0.6 -1.7 0.2 1.2 1.0 1.9 0.3 1.1 -0.1 -0.6
Medication: Ventolin 100micrograms inhaler 0.5 0.6 2.2 -0.7 -0.4 -0.2 -0.1 -1.0 -1.3 0.2 -0.7 -0.8 -0.9 -1.0 0.5 -0.8 -1.0 -0.4 -0.2 -0.7 -1.0 -0.4 -1.0 -1.5 0.7 -0.2
Birth weight 3.2 6.9 25.6 -5.1 2.3 2.8 -1.0 0.5 1.8 1.2 1.3 3.5 -0.9 -0.8 5.0 1.9 0.7 -0.4 -0.1 2.5 1.8 4.7 0.7 1.6 3.7 -4.6
Chronic bronchitis/emphysema (mother) 2.3 2.7 6.6 0.7 -1.8 -1.7 -2.6 -1.5 -1.3 0.8 -1.8 -1.6 -1.9 -1.9 -0.7 -1.9 -2.0 -2.4 -1.6 -1.5 -1.4 -0.8 -1.9 -1.6 -1.9 0.1
High blood pressure (siblings) 0.5 0.7 3.4 -1.3 0.2 -0.6 -0.0 -1.1 -0.0 0.3 -0.1 -0.3 -1.4 -1.3 1.0 -0.6 -1.3 -1.9 -0.4 0.3 0.5 -0.5 -0.6 0.0 -0.3 -1.1
Forced vital capacity (FVC), Best measure 6.9 25.7 55.8 -2.6 5.9 5.9 3.2 5.0 6.4 3.9 4.8 6.8 3.6 4.1 4.1 6.3 5.4 2.1 3.4 5.8 6.3 7.5 5.2 7.1 3.6 -2.0
Body fat percentage 2.8 11.5 21.7 1.6 -3.7 -4.7 -2.9 -3.9 -3.6 -3.0 -3.2 -3.3 -3.4 -3.1 -3.0 -4.1 -3.5 -3.8 -3.4 -3.3 -3.9 -3.5 -3.2 -3.7 -3.1 1.6
Leg fat percentage (right) 3.2 12.0 28.9 2.5 -3.4 -5.4 -3.0 -3.7 -3.5 -2.6 -3.4 -3.5 -2.7 -2.5 -3.6 -3.9 -3.4 -3.8 -2.8 -3.1 -4.4 -4.1 -2.8 -3.8 -3.6 2.7
Arm fat-free mass (right) 4.1 21.7 62.4 -6.0 4.9 5.0 2.4 2.0 4.4 2.2 3.8 7.0 -0.3 0.8 6.8 4.7 3.3 -0.8 2.5 4.9 5.7 7.9 3.0 5.5 5.3 -6.4
Exposure to tobacco smoke outside home 0.5 0.6 2.6 1.5 0.1 -0.5 0.3 0.1 0.3 1.0 -0.4 -0.9 0.6 0.3 -1.6 -0.2 -0.4 -1.2 -0.1 -1.3 -0.0 0.2 -0.1 0.3 -1.0 1.5
Comparative body size at age 10 1.6 4.5 16.9 0.3 -1.7 -1.7 -4.1 -3.0 -2.0 -0.1 -1.4 -1.5 -2.9 -2.7 -0.0 -2.5 -2.7 -2.1 0.3 -1.4 -3.5 -2.2 -2.0 -2.4 -0.5 -0.8
Number of full brothers 0.5 0.6 1.9 -0.4 -0.8 -1.2 -0.7 -0.7 -0.9 -1.4 -0.3 -1.2 -0.8 -0.9 0.0 -0.9 -0.8 -0.7 -0.4 -0.0 -0.1 -1.3 -1.0 -0.6 -0.5 -0.8
Worry too long after embarrassment 2.6 4.4 13.6 1.0 -2.6 -3.7 -1.6 -2.2 -2.3 -2.6 -1.7 -2.1 -1.6 -1.5 -2.1 -2.0 -1.6 -1.7 -2.4 -2.8 -1.9 -1.4 -2.4 -1.8 -1.3 1.9
Seen a psychiatrist for nerves, anxiety, tension or depression 2.4 3.1 7.2 0.4 -2.5 -1.5 -0.0 -1.7 -1.8 -2.0 -2.7 -2.0 -2.0 -1.8 -1.0 -2.1 -1.5 -1.1 -2.1 -2.4 -1.3 -1.4 -2.2 -1.8 -1.6 0.2
Wheeze or whistling in the chest in last year 0.2 0.3 4.4 -0.3 0.2 -0.3 0.3 0.0 -0.1 -2.1 -0.2 0.6 0.1 0.4 -0.1 0.3 0.3 0.0 -0.1 0.7 -0.3 -0.5 0.6 -0.1 0.1 -0.0
Number of children fathered 1.0 1.1 3.4 1.7 -1.1 -1.8 -0.9 -0.3 -0.8 0.9 0.2 -0.8 -0.4 -0.2 -1.9 -0.9 -0.4 -0.5 -1.4 -1.0 -1.3 -0.8 -0.6 -1.0 -1.5 1.5
Reason for reducing amount of alcohol drunk: Health precaution 3.1 3.6 7.3 -0.6 2.2 1.4 0.8 2.1 2.1 0.5 2.3 2.7 1.9 1.9 1.1 2.5 2.5 0.9 0.9 2.5 1.9 2.3 2.3 2.2 2.2 -0.2
Age at first live birth 0.9 1.6 5.3 -2.2 -0.3 0.9 -2.3 -1.2 -0.1 0.9 -1.5 -0.1 -1.5 -1.6 1.9 -0.6 -1.2 -1.4 -0.4 -1.1 -1.2 0.9 -1.1 -0.9 1.8 -0.8
Pulse wave peak to peak time 0.1 0.1 0.6 0.5 0.1 -0.2 -0.6 -0.2 -0.3 0.3 0.6 -0.4 0.1 -0.1 -0.3 -0.2 -0.3 -0.1 0.4 0.5 0.1 -0.7 0.0 -0.5 -0.2 -0.5
Health satisfaction 0.3 0.3 1.6 -1.1 -0.5 -0.6 -0.3 -0.1 -0.4 -0.5 -1.3 0.1 -0.7 -0.7 0.7 -0.3 -0.5 -0.5 -0.3 -0.4 0.1 0.1 -0.5 -0.1 0.2 -1.2
Shortness of breath walking on level ground 1.1 1.4 4.2 -0.6 -1.1 -1.4 -0.8 -1.6 -1.4 -1.8 -0.7 -0.5 -1.4 -1.1 0.3 -1.3 -1.2 -0.6 -1.3 -1.0 -1.6 -2.0 -0.9 -0.9 -0.6 -0.7
Qualifications: College or University degree 0.9 2.8 16.6 -1.6 1.2 3.3 0.3 1.2 1.5 1.4 1.3 2.1 -0.2 0.1 1.4 1.7 1.5 -1.1 0.4 0.9 1.8 4.1 0.7 2.1 1.1 -0.9
Eye problems/disorders: None of the above 2.8 3.3 6.6 0.4 -2.3 -1.4 -2.4 -1.4 -1.9 -1.3 -2.5 -2.3 -1.1 -1.3 -1.0 -2.1 -2.3 0.5 -1.5 -2.0 -2.3 -2.5 -1.7 -2.6 -1.1 1.2
Mouth/teeth dental problems: Loose teeth 1.2 1.4 3.5 1.9 1.2 -0.3 0.4 1.1 1.5 -0.1 0.8 1.4 1.1 1.7 -1.5 1.5 1.6 -0.6 1.3 1.4 0.2 0.2 1.5 1.5 -0.9 1.2
Emphysema/chronic bronchitis 0.3 0.3 1.3 0.6 -0.1 -0.4 -0.4 1.1 0.6 -0.3 0.5 0.0 0.6 0.6 -1.1 0.4 0.6 -0.2 -0.4 0.4 0.2 0.2 0.6 0.5 -0.9 0.5
Medication for pain relief, constipation, heartburn 2.1 3.7 15.7 -3.1 1.4 4.0 0.6 0.3 1.2 0.4 0.8 1.1 0.2 -0.3 3.6 0.9 0.5 1.8 2.3 1.3 1.6 1.9 0.3 1.0 3.1 -3.4
Neck or shoulder pain in last month 1.0 1.5 5.2 1.2 -1.0 -2.3 -1.8 -1.2 -1.0 0.0 -1.1 -0.8 -0.9 -0.7 -1.4 -1.2 -1.1 -1.2 -0.7 -0.9 -1.4 -1.7 -0.8 -1.4 -1.5 0.6
Medication: Blood pressure 0.4 0.8 4.5 -0.2 -0.4 -0.9 -0.3 -1.1 -0.7 1.1 -0.4 -0.1 -1.1 -0.9 -0.1 -0.7 -0.9 -2.1 -2.0 -0.3 -0.3 0.2 -0.8 -0.6 -0.8 0.4
Angina (self-reported) 0.6 0.8 5.2 0.3 -0.8 -0.7 -0.9 -0.9 -1.3 0.1 -0.8 -0.4 -0.4 -0.2 0.3 -0.8 -0.6 1.6 -0.0 -0.7 -1.4 -2.3 -0.5 -1.1 -0.6 -0.2
Migraine (self-reported) 0.9 1.1 3.5 1.5 -1.1 -0.9 -0.4 -0.6 -1.1 0.2 -1.1 -1.4 -0.1 -0.3 -1.9 -1.0 -0.5 -0.8 -0.7 -0.8 -1.5 -1.5 -0.9 -1.1 -1.4 1.4
Medication: Ibuprofen 3.3 4.0 12.2 2.7 -1.6 -3.4 -1.8 -0.8 -1.6 -0.1 -1.5 -1.4 -0.8 -0.6 -3.5 -1.4 -1.3 -2.1 -2.4 -1.9 -2.7 -2.0 -0.7 -2.1 -2.3 3.0
Medication: Allopurinol 1.7 2.2 4.2 -0.2 1.5 2.0 2.0 1.5 1.6 1.1 2.0 1.6 1.1 1.2 0.6 1.7 1.8 1.2 1.7 1.1 1.7 2.1 1.5 1.5 1.2 -0.6
Medication: Omeprazole 0.8 1.0 4.5 1.6 -1.1 -2.1 -0.6 -0.3 -0.4 -0.6 -0.8 -0.6 -0.2 -0.0 -1.6 -0.7 -0.2 -1.1 -1.6 -0.5 -1.1 -0.2 -0.2 -0.6 -1.8 0.9
Medication: Seretide 50 evohaler 4.4 5.1 11.6 -2.1 2.7 3.1 2.1 2.4 2.2 -0.8 2.1 2.7 1.5 1.5 2.4 2.6 2.3 1.3 2.1 2.7 3.4 1.9 2.2 2.3 2.4 -1.6
Mean time to correctly identify matches 3.1 6.0 18.2 -3.1 2.6 2.2 3.8 1.4 2.2 0.7 2.3 2.8 0.2 0.4 3.4 2.3 1.7 -0.9 1.5 2.3 4.3 2.9 1.3 3.1 3.1 -2.7
Heart disease (mother) 1.1 1.3 3.3 0.0 -1.1 -0.1 -0.2 -1.3 -0.6 -0.2 -0.8 -1.7 -1.7 -1.8 -0.2 -1.7 -1.6 -1.8 -1.4 -1.2 -0.2 -0.1 -1.5 -0.5 -1.6 -0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.8 1.0 5.1 -2.1 -0.4 0.4 -0.2 -0.3 -0.5 0.1 0.4 0.8 -0.7 -0.7 2.1 -0.2 -0.4 1.1 -0.2 0.4 -0.3 0.4 -0.2 -0.8 1.8 -2.3
Whole body fat mass 0.8 3.5 12.5 -1.1 -1.5 -2.2 -1.9 -2.8 -1.7 -1.8 -1.4 -0.6 -3.1 -2.6 0.1 -2.0 -2.0 -3.5 -2.0 -1.1 -1.4 -0.5 -1.9 -1.5 -0.4 -1.2
Leg fat mass (right) 0.9 3.4 12.4 -0.6 -1.4 -2.8 -2.3 -2.7 -1.7 -1.6 -1.6 -0.7 -2.8 -2.3 -0.3 -2.0 -2.1 -3.5 -1.6 -0.9 -1.9 -1.0 -1.7 -1.6 -0.8 -0.5
Arm predicted mass (right) 4.1 21.2 60.7 -5.9 4.9 5.0 2.3 1.9 4.3 2.2 3.7 6.9 -0.2 0.8 6.8 4.6 3.3 -0.8 2.6 4.8 5.7 7.8 2.9 5.4 5.4 -6.3
Pulse rate, automated reading 1.0 3.2 8.0 -2.3 2.1 1.2 0.4 0.9 1.8 -1.1 1.5 2.8 -0.2 0.3 2.1 1.9 1.2 -1.9 -0.0 2.6 2.6 2.5 1.5 2.5 1.4 -1.8
Alcohol intake frequency. 3.4 8.0 37.7 3.8 -2.7 -3.8 -1.8 -1.8 -2.7 0.1 -2.2 -3.6 -0.6 -0.6 -3.8 -2.9 -2.5 0.4 -1.7 -1.2 -2.8 -6.1 -1.4 -3.1 -4.4 2.1
Comparative height size at age 10 4.1 22.8 72.4 -3.7 5.0 5.6 3.4 3.7 5.5 3.3 4.8 7.5 1.1 2.5 4.0 5.6 4.9 -0.1 1.3 4.9 6.6 8.5 4.2 6.4 4.0 -3.4
Number of full sisters 0.3 0.4 2.6 1.0 -0.1 -1.6 0.0 -0.4 -0.2 -0.4 -0.1 0.0 0.1 0.1 -0.7 -0.1 -0.1 -0.0 0.1 -0.0 -1.1 -1.1 0.0 -0.8 -0.3 0.7
Suffer from ‘nerves’ 6.9 10.9 18.7 0.1 -4.0 -3.2 -1.4 -4.2 -4.0 -0.8 -3.5 -4.0 -4.0 -3.9 -1.3 -4.2 -4.1 -2.9 -3.9 -4.3 -2.9 -2.3 -4.2 -3.8 -2.1 1.1
Overall health rating 1.1 2.4 4.6 -1.5 -1.3 -1.3 -1.5 -2.0 -1.7 -2.2 -1.7 -0.9 -1.9 -1.9 0.7 -1.6 -1.9 -1.2 -1.9 -0.7 -0.9 -1.2 -1.7 -2.0 -0.2 -1.8
Chest pain or discomfort 0.4 0.6 4.9 -0.5 0.7 -0.1 0.8 0.5 0.9 -2.2 0.1 1.1 0.2 0.4 0.3 0.7 0.8 -0.3 0.3 0.9 0.7 0.1 0.9 0.9 -0.4 -0.6
Had major operations 4.7 5.5 11.0 -1.1 2.7 1.5 3.1 2.4 2.5 -0.7 3.3 2.4 1.9 1.9 1.3 2.8 2.8 1.0 2.1 2.7 3.3 2.9 2.2 3.2 1.7 -1.6
Age at last live birth 0.5 0.8 2.5 -1.6 -0.3 0.7 -1.6 -0.6 -0.2 0.7 -0.8 -0.1 -1.1 -1.2 1.1 -0.5 -0.7 -0.6 -0.1 -0.9 -0.2 1.3 -0.9 -0.6 1.3 -0.7
Family relationship satisfaction 0.3 0.4 2.1 0.4 -0.3 -0.9 -0.1 -0.3 0.1 -0.1 -0.6 -0.2 -0.6 -0.3 -0.8 -0.2 -0.2 -1.4 -0.7 -0.9 0.4 0.5 -0.5 0.2 -0.2 1.1
Leg pain on walking 0.6 0.8 1.8 1.2 0.1 0.6 0.1 1.1 0.8 -0.4 0.0 -0.0 1.3 1.3 -1.1 0.6 1.1 1.3 1.0 -0.4 0.5 -0.1 0.7 1.1 -0.9 1.3
Qualifications: NVQ or HND or HNC or equivalent 0.7 0.9 4.3 2.1 -0.4 -1.4 0.7 0.2 -0.4 -0.6 -0.4 -0.8 1.1 0.9 -2.0 -0.2 0.1 0.3 0.1 -0.4 -0.6 -1.3 0.2 -0.4 -1.3 1.2
Commuting to job workplace: Car/motor vehicle 1.1 1.3 4.8 0.0 1.2 1.3 0.9 0.9 0.7 1.9 0.8 1.0 1.1 1.3 1.1 1.1 1.3 2.2 1.3 0.8 1.5 0.4 1.0 1.2 0.6 -1.0
Illness, injury, bereavement, stress in last 2 years 1.3 1.6 6.1 -1.7 1.2 1.3 1.6 0.2 0.7 0.5 1.3 1.7 -0.0 0.1 2.0 1.2 1.0 -0.3 1.2 0.9 1.3 0.8 0.5 1.2 2.5 -1.6
Medication: Aspirin 0.2 0.3 1.4 0.4 -0.3 -1.2 -0.6 -0.6 -0.5 0.7 0.4 -0.0 -0.5 -0.3 -0.1 -0.3 -0.3 -0.5 -1.0 -0.3 0.0 -1.0 -0.2 -0.2 -0.9 0.4
Supplements: Vitamin C 0.1 0.1 0.9 0.1 0.0 -0.4 0.7 0.5 0.1 -0.2 -0.3 -0.1 -0.1 -0.1 -0.1 0.0 0.2 0.1 0.2 -0.1 0.9 0.2 0.1 0.5 -0.5 -0.6
Knee pain experienced in last month 0.7 1.1 3.7 0.3 -0.9 -0.9 -0.6 -1.1 -0.7 -1.9 -1.4 -1.2 -1.0 -1.1 -0.9 -0.9 -0.8 -1.8 -1.3 -1.2 -0.1 -0.2 -1.4 -1.0 -0.9 -0.5
Hypertension (Self-reported) 0.7 1.9 11.2 -0.9 -0.8 -0.5 -1.0 -1.8 -0.9 0.6 -2.1 0.0 -1.9 -1.5 0.0 -1.1 -1.3 -3.3 -2.9 -0.2 -0.4 0.6 -1.1 -1.0 -0.8 0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.5 3.1 0.3 -0.3 -1.6 0.4 -0.6 -0.7 -1.3 0.4 -0.3 -0.6 -0.6 -0.5 -0.4 -0.4 -1.8 -0.9 -0.9 -0.1 -0.2 -0.5 -0.2 0.1 0.5
Illnesses of father: Heart disease 0.6 0.8 1.6 1.1 0.9 0.2 0.7 1.1 1.0 0.1 1.1 0.6 1.2 1.2 -0.8 1.1 1.1 0.1 0.8 0.9 0.8 0.3 1.0 0.9 -0.4 1.3
Illnesses of siblings: Diabetes 2.3 2.8 8.5 -1.9 -1.0 -1.3 -0.8 -2.4 -1.3 0.4 -0.0 -1.5 -2.6 -2.9 1.5 -1.8 -2.4 -2.5 -1.1 -1.1 -0.8 -0.5 -2.3 -1.7 0.7 -1.6
Smoking status: Previous 0.9 1.3 5.2 -1.6 0.8 -0.1 -1.0 0.2 0.9 2.3 0.2 1.8 -0.4 -0.2 1.4 0.9 0.5 -0.9 1.0 0.6 0.0 2.0 0.6 0.8 2.3 -0.9
Forced expiratory volume in 1-second (FEV1), predicted 0.7 1.6 11.0 -1.6 0.6 0.4 -0.1 0.4 1.0 2.5 0.1 1.9 -0.5 -0.0 1.5 0.8 0.6 0.0 -0.2 0.8 0.7 3.3 0.2 0.8 1.3 -1.9
Whole body fat-free mass 5.0 28.9 76.9 -7.4 5.7 6.0 2.3 2.3 4.9 2.9 4.3 7.9 -0.1 0.9 8.1 5.4 3.7 -0.6 3.1 5.8 6.3 8.8 3.4 6.0 6.6 -7.5
Leg fat-free mass (right) 2.8 15.3 49.7 -6.8 3.4 4.3 1.0 0.5 2.6 0.8 2.6 5.2 -1.6 -0.9 6.8 3.0 1.8 -1.4 1.7 3.8 4.4 6.2 1.4 3.6 5.5 -7.0
Arm fat percentage (left) 3.1 12.6 20.3 0.6 -3.9 -4.3 -3.6 -4.4 -4.1 -2.8 -3.0 -3.8 -3.9 -3.8 -2.2 -4.5 -4.0 -3.8 -3.4 -3.4 -4.2 -3.4 -3.8 -4.2 -2.4 0.4
Average weekly red wine intake 2.2 3.3 12.3 -2.7 2.0 3.2 1.7 1.1 1.9 1.1 0.4 1.8 0.6 0.5 2.0 1.9 1.4 -0.5 1.3 1.1 2.1 3.5 0.9 1.9 2.7 -0.9
Handedness (chirality/laterality): Left-handed 0.2 0.3 1.1 -0.6 0.0 -0.8 0.7 -0.6 -0.0 0.6 -0.2 0.1 -0.5 -0.4 0.3 -0.1 -0.3 -1.1 0.8 0.4 0.2 -0.4 -0.2 -0.1 1.0 -0.1
Mood swings 1.8 3.4 12.4 2.9 -1.7 -2.7 -0.2 -1.2 -0.7 0.4 -1.9 -1.6 -1.0 -0.6 -3.2 -1.6 -1.1 -2.3 -1.0 -2.2 -1.2 -0.9 -1.0 -0.5 -3.5 2.7
Loneliness, isolation 1.8 2.5 10.2 3.2 -1.4 -2.6 0.3 -0.2 -0.0 -1.5 -1.2 -1.1 -0.1 0.3 -3.1 -0.9 -0.1 -1.2 -0.8 -1.7 -0.0 -0.2 -0.2 0.1 -3.1 2.8
Long-standing illness, disability or infirmity 0.2 0.3 1.8 0.4 0.1 -1.4 -0.7 -0.4 -0.1 -0.6 -0.1 -0.6 0.5 0.1 -0.6 -0.2 -0.3 -0.3 0.1 0.6 -0.5 -0.8 -0.0 -0.8 -0.4 -0.1
Ever had bowel cancer screening 0.6 0.7 3.6 -1.5 0.6 0.8 0.4 0.5 0.9 0.5 -0.9 1.1 -0.1 -0.1 1.1 0.8 0.3 -1.2 0.2 0.4 1.1 1.9 0.1 0.3 1.0 -0.1
Diabetes diagnosed by doctor 0.3 0.5 2.1 -0.6 0.3 -1.5 -0.0 -1.0 -0.7 0.8 0.9 0.0 -0.7 -0.6 0.3 -0.3 -0.5 -1.4 -0.7 0.4 0.3 -1.1 -0.4 -0.8 0.3 -0.8
Ever had stillbirth, spontaneous miscarriage or termination 0.3 0.3 1.7 1.3 -0.1 -0.1 0.5 0.7 0.4 -0.8 0.3 -0.3 0.8 0.7 -0.9 0.3 0.4 0.3 0.4 -0.1 0.5 0.7 0.2 0.4 -1.0 0.3
Friendships satisfaction 2.7 3.3 10.9 -0.9 2.0 1.8 2.5 1.7 1.9 0.0 1.6 2.1 1.3 1.5 1.2 2.2 2.1 0.6 2.0 1.4 3.3 2.1 1.3 2.3 2.0 -1.1
Qualifications: nursing, teaching 0.9 1.4 6.8 -0.9 1.0 1.9 1.7 0.4 1.0 1.2 0.6 1.2 -0.2 0.1 1.1 1.1 1.0 -0.4 0.4 0.0 1.9 2.6 0.3 1.6 1.1 -0.5
Commuting to job workplace: Walk 2.9 3.1 10.8 -2.3 -1.0 -0.7 -1.1 -2.2 -1.4 -1.0 -1.4 -1.1 -2.8 -2.8 1.3 -1.6 -2.4 -3.3 -1.1 -0.5 -0.9 -0.4 -2.2 -1.4 1.0 -2.4
Eye problems/disorders: Cataract 0.3 0.3 2.1 -0.2 -0.0 -0.6 0.1 -0.7 -0.4 1.4 0.5 0.3 -0.6 -0.4 0.3 -0.1 -0.0 -1.1 -1.4 0.3 0.1 0.4 -0.3 0.2 0.1 -0.7
Mouth/teeth dental problems: Mouth ulcers 0.4 0.6 1.8 -1.2 0.7 1.2 0.4 0.3 0.4 0.3 0.8 1.2 -0.4 -0.2 1.2 0.7 0.3 -0.1 -0.6 0.4 1.0 1.3 0.3 0.5 1.1 -0.9
Medication for cholesterol 0.3 0.4 2.1 -0.7 -0.4 -0.2 -0.3 0.2 -0.4 0.9 0.4 -1.0 0.1 -0.4 0.7 -0.4 -0.4 1.5 0.6 -0.3 -0.4 -0.5 -0.6 -0.5 1.1 -1.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 3.7 4.4 9.5 -1.8 2.5 1.1 0.8 2.0 2.4 -0.1 2.6 3.0 1.7 1.9 1.7 2.7 2.5 0.9 1.7 3.1 1.2 2.2 2.6 2.3 2.9 -1.1
Back pain experienced in last month 0.7 1.0 4.2 -0.6 -0.7 -2.1 -1.2 -1.0 -0.9 0.1 -1.5 -0.7 -0.8 -0.8 0.1 -0.8 -0.9 -1.1 -0.8 -0.1 -1.5 -1.0 -0.7 -1.3 0.6 -0.9
Mineral and other dietary supplements 0.8 1.1 5.2 -0.0 0.7 1.2 -1.1 0.7 0.7 1.1 1.0 1.0 1.2 1.1 0.9 0.7 0.6 2.1 0.7 2.3 -0.4 -0.0 1.1 -0.1 -0.3 -1.4
Breast cancer (self-reported) 1.1 1.4 11.6 -1.6 0.8 0.9 -0.2 -0.0 0.1 -0.2 0.6 1.2 0.0 0.1 2.1 0.8 0.4 1.4 0.6 1.7 0.9 0.6 0.2 0.1 1.4 -3.4
Asthma (self-reported) 0.4 0.8 4.0 -1.9 0.1 1.5 -0.3 -0.6 -0.2 -0.5 -0.0 0.4 -1.0 -1.0 2.0 -0.1 -0.2 0.3 0.4 0.3 -0.1 1.1 -0.5 -0.2 1.1 -1.8
Osteoporosis (self-reported) 0.2 0.2 1.3 0.3 -0.3 0.6 -0.5 -0.2 -0.3 0.6 -0.5 -0.6 0.3 0.1 -0.7 -0.4 -0.3 0.0 -0.7 -0.3 -1.1 0.1 -0.2 -0.6 -0.4 0.5
Osteoarthritis (self-reported) 0.5 0.6 1.7 0.8 -0.7 -0.7 -0.3 -0.4 -0.3 -1.1 -1.3 -0.8 -0.2 -0.4 -1.2 -0.6 -0.2 -0.8 -0.6 -1.1 -1.1 -0.5 -0.6 -0.9 -0.4 1.3
Medication: Aspirin 0.1 0.2 0.7 -0.0 0.1 -0.6 -0.3 -0.3 -0.3 0.8 0.7 0.5 -0.5 -0.1 0.3 0.1 -0.0 -0.2 -0.7 0.1 0.5 -0.6 0.1 -0.1 -0.5 0.2
Medication: Gliclazide 0.7 0.8 2.3 -0.7 -0.6 -0.9 -0.6 -1.0 -0.9 -0.1 -0.5 -1.0 -1.1 -1.2 -0.1 -1.0 -1.0 -1.5 -0.9 -0.4 -0.1 -1.2 -1.1 -1.2 -0.3 -0.1
Illnesses of father: None of the above (group 1) 1.3 1.6 5.6 1.3 -1.6 -2.4 -0.9 -1.1 -1.7 -0.5 -1.1 -1.2 -0.7 -0.6 -1.2 -1.4 -1.0 0.2 -0.7 -1.2 -1.8 -1.9 -0.9 -1.7 -1.0 0.6
Smoking status: Current 2.0 3.2 16.4 3.5 -1.0 -2.2 -0.2 0.6 -0.3 -2.6 -0.1 -1.1 1.2 1.5 -4.0 -0.2 0.6 0.0 -0.6 -0.3 -1.1 -1.7 0.3 -0.7 -2.8 3.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.2 2.6 8.6 -2.0 1.8 2.9 0.6 0.8 1.7 0.9 1.5 1.4 0.3 0.1 2.5 1.5 0.9 -0.2 0.6 1.5 2.1 2.5 0.8 2.2 1.7 -2.0
Whole body water mass 4.8 28.2 77.3 -7.5 5.6 5.9 2.1 2.1 4.8 2.8 4.2 7.7 -0.3 0.7 8.1 5.2 3.5 -0.7 2.9 5.7 6.2 8.8 3.2 5.9 6.6 -7.6
Leg predicted mass (right) 2.8 15.5 50.4 -6.8 3.4 4.3 1.0 0.6 2.6 0.8 2.6 5.2 -1.6 -0.9 6.8 3.0 1.8 -1.4 1.7 3.8 4.5 6.2 1.4 3.6 5.5 -7.1
Arm fat mass (left) 0.9 3.9 10.6 -1.5 -1.6 -1.9 -2.5 -2.9 -2.0 -1.6 -1.2 -0.8 -3.3 -2.8 0.5 -2.2 -2.2 -3.2 -2.0 -1.1 -1.6 -0.4 -2.1 -1.8 -0.1 -1.8
Number of self-reported non-cancer illnesses 0.2 0.3 2.1 -0.3 -0.1 -0.0 0.3 -0.5 -0.3 -0.9 -0.6 0.0 -0.8 -0.7 -0.0 -0.2 -0.3 -1.4 -1.1 -0.2 0.2 0.3 -0.4 -0.0 -0.8 -0.0
Average weekly champagne plus white wine intake 0.5 0.6 1.7 -0.9 1.0 0.5 -0.1 0.4 0.4 -1.3 1.0 1.0 0.1 0.1 0.5 1.0 0.9 -1.1 0.1 0.9 1.1 0.7 0.3 1.1 0.9 -0.7
Miserableness 4.9 8.6 35.5 5.4 -2.9 -3.7 -0.1 -1.0 -1.3 -2.0 -1.7 -2.7 -0.3 0.1 -6.0 -2.1 -0.7 -2.5 -1.3 -3.3 -2.3 -1.8 -1.3 -1.3 -4.8 5.9
Guilty feelings 12.7 19.3 56.0 6.4 -4.9 -7.3 -2.0 -2.5 -3.2 -3.1 -2.4 -5.0 -1.4 -1.2 -7.5 -4.0 -2.5 -2.7 -4.4 -4.5 -3.9 -4.9 -3.0 -3.1 -6.7 6.1
Wears glasses or contact lenses 0.9 1.0 3.7 0.0 -1.1 -1.1 -0.9 -1.5 -1.4 -1.9 -0.8 -0.4 -1.3 -0.8 -0.4 -0.9 -0.5 -0.8 -1.4 -0.3 -1.5 -1.1 -1.1 -0.9 -0.1 -0.4
Ever taken oral contraceptive pill 1.1 1.2 5.2 -0.2 1.3 0.1 1.3 1.2 1.1 2.3 1.0 0.7 1.2 1.1 0.3 1.3 1.2 -0.0 1.0 0.8 0.4 1.8 1.0 1.3 1.1 0.2
Hearing aid user 0.3 0.3 3.3 0.5 0.0 0.1 -1.0 0.5 0.2 -0.3 0.1 0.5 0.7 0.6 -0.3 0.3 0.5 1.8 0.4 -0.3 -0.6 -0.1 0.5 -0.3 -0.1 0.5
Mother’s age at death 0.6 0.8 3.5 -1.0 0.0 1.9 0.1 -1.2 -1.0 -0.3 -0.3 -0.5 -0.8 -1.1 1.3 -0.6 -1.0 -0.4 0.1 -1.2 -0.5 0.1 -0.9 -0.7 1.2 -0.6
Financial situation satisfaction 1.4 1.7 6.3 1.1 -1.2 -2.3 -1.3 -0.9 -1.2 -0.8 -1.4 -0.8 -0.7 -0.5 -1.5 -1.1 -1.2 -1.2 -1.4 -0.9 -1.4 -2.5 -1.0 -1.4 -1.3 1.6
Tinnitus: Yes, now most or all of the time 0.5 0.6 6.1 0.8 -0.8 -0.1 -0.9 0.0 0.4 -2.5 0.2 -0.4 0.0 0.3 -1.1 -0.4 0.2 0.4 -0.9 -0.1 -1.0 -0.6 0.0 -0.6 -0.9 0.5
Commuting to job workplace: Public transport 1.9 2.3 8.7 1.9 -1.4 -1.5 0.2 -0.5 -1.4 -2.8 -1.0 -2.1 -0.3 -0.5 -3.0 -1.1 -0.6 -1.5 -1.3 -1.5 -0.6 -1.4 -1.0 -1.1 -1.8 2.2
Eye problems/disorders: Glaucoma 0.5 0.6 2.2 0.3 0.9 -0.4 0.7 0.7 0.7 1.5 1.2 1.1 0.5 0.6 -0.1 0.7 0.7 -0.6 0.8 0.4 0.3 0.4 1.0 0.9 0.4 0.7
Medication: Blood pressure 0.5 0.9 9.9 -0.1 -0.1 0.2 0.2 -1.0 -0.1 0.0 -1.7 0.2 -1.3 -0.8 -0.6 -0.5 -0.5 -3.1 -1.3 0.0 0.6 0.5 -0.3 0.2 -1.4 0.5
Pain type(s) experienced in last month: Hip pain 0.4 0.6 2.8 0.6 -0.6 -0.7 -1.7 -0.4 -0.3 0.9 -0.7 -0.6 -0.2 -0.4 -0.4 -0.6 -0.5 -0.6 -0.9 -0.8 -1.5 0.4 -0.3 -1.0 -0.0 0.8
Supplements: Fish oil (including cod liver oil) 0.8 1.1 7.3 1.4 -0.5 -1.4 2.0 -0.1 -0.4 -0.9 -0.1 -0.7 0.1 0.1 -1.6 -0.1 0.3 -0.6 -0.1 -2.1 0.5 -0.2 -0.4 0.4 0.1 2.7
High cholesterol (Self-reported) 0.6 1.1 4.7 1.8 -0.4 -1.0 -0.9 -0.1 0.3 0.5 -1.4 0.8 0.5 1.0 -1.7 0.2 0.5 -0.5 -0.2 -0.1 -1.4 -0.2 0.7 0.1 -2.1 2.2
Medication: Bendroflumethiazide 0.9 1.4 9.2 -0.5 -0.6 -0.1 -1.2 -1.8 -0.4 -0.0 -1.5 0.3 -2.0 -1.4 0.2 -1.0 -1.1 -3.0 -1.7 -0.4 -0.9 0.7 -0.9 -0.8 -0.9 0.2
Medication: Paracetamol 2.1 3.4 18.9 4.3 -0.5 -2.3 1.2 1.2 0.2 0.4 0.2 -0.8 1.3 1.6 -4.0 0.0 1.0 -0.5 -0.4 -0.7 -0.2 -0.7 0.9 0.5 -3.5 3.7
Medication: Lisinopril 1.7 2.3 5.8 0.2 1.7 1.5 1.1 1.3 1.4 1.1 2.4 2.1 1.5 1.8 0.8 1.7 1.6 1.9 0.4 2.2 1.6 1.4 1.8 1.6 0.1 -0.6
Medication: Atorvastatin 0.4 0.5 1.4 0.5 -0.7 -0.6 -0.6 -0.6 -0.4 -0.2 -1.0 -0.5 -0.6 -0.5 -0.8 -0.7 -0.7 -1.2 -0.1 -0.5 -1.0 -1.1 -0.4 -0.7 -1.2 1.0
Illnesses of father: High blood pressure 0.5 0.7 2.4 -0.1 -0.8 0.7 -0.7 -0.4 -0.3 -1.4 -0.9 -1.0 -0.4 -0.5 -0.6 -0.9 -0.8 -0.3 -1.6 -0.9 -0.9 -0.1 -0.7 -0.9 -0.9 1.1
Alcohol drinker status: Never 1.1 1.3 4.4 1.1 0.9 0.1 0.6 1.3 1.0 1.6 0.4 1.4 1.2 1.6 -0.8 1.0 1.2 1.1 1.3 2.1 0.6 -0.8 1.7 1.0 -1.2 -0.1
Ever smoked 0.4 0.7 2.9 -0.2 0.5 -0.6 -0.8 0.5 0.9 1.1 -0.5 0.7 0.4 0.4 -0.3 0.7 0.6 -1.0 0.9 -0.2 -0.8 1.4 0.7 0.2 1.4 1.7
Basal metabolic rate 3.5 19.9 57.0 -6.6 4.5 4.8 1.5 1.4 3.8 2.0 3.4 6.6 -0.7 0.2 7.0 4.1 2.8 -1.2 2.2 4.8 5.2 7.5 2.5 4.8 5.6 -6.7
Leg fat percentage (left) 3.4 12.4 25.9 2.0 -3.5 -5.1 -3.0 -4.0 -3.7 -3.2 -3.6 -3.6 -3.1 -2.9 -3.2 -4.1 -3.6 -3.8 -3.0 -3.2 -4.3 -4.2 -3.1 -3.9 -3.4 2.1
Arm fat-free mass (left) 4.0 20.9 60.2 -5.9 5.0 5.0 2.0 2.0 4.4 2.2 3.7 7.0 -0.0 1.0 6.7 4.7 3.4 -0.7 2.5 5.0 5.4 7.8 3.0 5.3 5.2 -6.1
Number of operations (self-reported) 3.6 5.5 10.8 -1.2 2.9 1.2 3.1 2.0 2.9 1.0 2.6 3.2 1.6 1.9 1.4 3.0 2.7 0.4 1.6 2.8 2.9 3.3 2.5 3.2 1.4 -1.1
Average weekly beer plus cider intake 1.1 1.6 3.5 -0.8 -1.2 -1.2 -0.6 -1.7 -1.9 0.2 -1.3 -1.2 -1.8 -1.7 1.1 -1.6 -1.9 -0.5 -0.5 -1.0 -1.2 -1.0 -1.6 -1.3 0.4 -1.5
Irritability 2.0 3.4 7.2 1.3 -2.1 -2.4 -1.9 -1.6 -1.4 0.6 -2.1 -1.7 -2.1 -1.8 -2.0 -2.1 -1.9 -2.7 -1.7 -2.5 -1.7 -0.2 -1.7 -1.4 -1.9 1.9
Risk taking 2.3 3.3 11.1 0.3 1.9 0.9 1.8 2.4 2.9 1.0 1.7 1.9 1.6 1.6 -0.2 2.2 2.1 -0.2 2.0 1.9 2.1 3.3 1.9 2.2 0.2 -0.2
Ever had prostate specific antigen (PSA) test 0.2 0.3 2.6 -0.8 -0.2 0.2 1.6 -0.1 -0.4 -0.6 -0.2 -0.2 -0.0 -0.1 0.5 0.1 0.5 0.4 -0.2 -0.2 0.2 0.3 -0.2 0.3 0.8 0.2
Fractured/broken bones in last 5 years 0.5 0.6 2.4 0.9 -0.5 -0.4 -1.6 -0.6 0.1 0.6 -1.5 0.2 -0.7 -0.3 -1.0 -0.5 -0.2 -0.5 -0.7 -0.7 -1.2 1.0 -0.5 -0.7 -0.6 0.5
Age started oral contraceptive pill 1.1 1.3 2.7 -0.3 -1.1 -0.4 -1.3 -1.5 -1.2 -0.9 -0.8 -1.2 -1.6 -1.6 0.4 -1.4 -1.2 -0.7 -1.3 -0.7 -1.0 -1.4 -1.6 -1.4 -0.6 -1.2
Diastolic blood pressure, automated reading 1.3 4.0 10.9 -0.4 -1.8 -1.1 -0.7 -2.4 -2.1 -1.4 -2.3 -2.1 -2.5 -2.5 -1.1 -2.3 -2.6 -3.3 -3.2 -2.1 -1.6 -0.9 -2.3 -1.8 -1.5 -0.2
Ever depressed for a whole week 2.3 2.8 6.8 1.9 -1.9 -2.0 -0.1 -0.9 -1.3 -2.1 -1.2 -2.2 -0.9 -1.0 -2.6 -1.8 -1.3 -1.6 -1.0 -2.3 -1.0 -2.1 -1.7 -1.6 -2.2 1.6
Unable to work because of sickness or disability 0.8 1.1 4.2 1.5 -0.3 -1.9 1.1 -0.4 0.0 -2.0 0.0 -0.5 0.3 0.6 -1.9 -0.2 0.2 -0.4 -0.3 -0.2 -0.8 -1.9 0.2 -0.6 -1.3 1.6
Commuting to job workplace: Cycle 0.8 1.0 3.8 -1.9 -0.6 -0.1 -1.0 -0.7 -0.6 -0.8 -1.5 -0.3 -1.3 -1.5 0.7 -0.7 -0.8 -1.3 -1.0 -0.7 -0.9 0.4 -0.5 -0.9 1.4 -0.2
Myopia 0.4 0.6 1.5 0.2 0.6 -0.1 0.8 1.0 0.4 -1.0 1.2 0.7 0.9 0.9 -0.8 0.8 0.7 -0.3 0.4 0.9 1.1 0.2 0.9 0.8 0.1 1.2
Vascular/heart problems diagnosed by doctor 0.5 1.3 7.4 0.9 0.5 0.3 0.5 1.7 0.9 -0.1 1.5 0.0 1.6 1.4 -0.3 0.9 1.1 2.7 2.4 0.3 0.1 -0.1 1.0 0.6 0.6 -0.1
Cholesterol lowering medication 0.5 0.7 1.5 0.3 1.0 0.8 1.2 0.5 1.2 -0.2 -0.3 1.2 0.6 0.8 -0.1 1.0 1.2 -0.6 0.3 0.7 1.1 0.9 0.8 1.1 -0.6 0.1
Medication: Omeprazole (e.g. Zanprol) 2.5 3.0 8.7 2.0 -2.1 -2.9 -1.4 -0.9 -1.3 -1.0 -2.1 -1.5 -0.8 -0.6 -2.5 -1.6 -0.9 -1.6 -2.6 -1.6 -2.3 -0.6 -1.0 -1.5 -2.5 1.5
Pain experienced in last month 1.3 2.1 4.0 -0.1 1.4 2.0 0.8 1.6 1.7 0.8 1.9 1.8 1.5 1.6 0.8 1.7 1.7 2.0 1.3 1.6 1.0 1.8 1.7 1.9 0.5 0.2
Supplements: Calcium 0.4 0.5 2.2 -0.2 0.3 0.7 -1.5 0.6 0.6 0.9 -1.2 0.6 -0.2 0.3 0.1 0.4 0.4 -0.2 1.3 0.0 -0.2 1.3 0.4 1.0 0.3 0.3
Basal cell carcinoma (self-reported) 0.1 0.2 0.8 0.2 0.3 0.5 0.7 0.0 -0.0 0.2 0.1 0.2 0.7 0.6 0.3 0.4 0.4 0.9 0.3 0.4 -0.2 0.1 0.2 0.2 0.6 0.4
Heart attack/myocardial infarction (self-reported) 2.3 3.0 5.7 -0.9 2.3 1.6 1.6 1.4 2.0 1.2 2.1 1.5 1.4 1.1 2.0 1.8 1.3 1.3 2.3 1.9 2.4 1.2 1.6 2.0 1.4 -2.1
Deep venous thrombosis (DVT) (self-reported) 1.2 1.6 7.6 0.3 1.3 -0.1 1.8 1.0 1.1 0.0 2.8 0.8 1.4 1.3 0.3 1.2 1.4 2.3 1.1 1.2 1.7 0.4 1.0 0.9 0.5 -0.3
Heart disease (siblings) 0.6 0.7 3.7 0.3 -1.0 -1.9 -0.7 -0.8 -0.4 0.3 0.0 -0.8 -0.6 -0.4 -0.9 -0.9 -0.7 -0.6 -0.5 0.4 -1.9 -1.1 -0.2 -1.0 -0.2 0.1
Alcohol drinker status: Previous 1.0 1.2 4.8 1.8 -1.3 -0.2 -1.5 -0.3 -0.5 -0.1 -1.2 -1.1 -0.1 -0.1 -1.2 -0.9 -0.9 0.8 -0.8 -0.8 -1.2 -1.8 -0.4 -1.1 -2.2 1.0
Pack years of smoking 0.4 0.6 5.3 0.3 -0.1 -2.3 -0.5 -0.5 -0.5 -0.5 1.2 -0.1 0.3 0.3 -0.2 -0.0 -0.1 0.7 -0.0 1.0 -0.3 -1.5 0.1 -0.5 -0.0 -0.7
Impedance of whole body 1.9 10.1 44.2 6.0 -2.8 -3.4 -0.0 0.0 -1.3 -1.0 -2.2 -3.3 0.9 0.9 -6.7 -2.0 -0.7 -0.5 -2.1 -3.3 -2.3 -3.5 -0.6 -1.9 -5.2 6.6
Leg fat mass (left) 1.1 4.3 13.6 -0.8 -1.7 -2.8 -2.5 -3.1 -2.0 -2.1 -1.7 -0.9 -3.2 -2.7 -0.2 -2.3 -2.4 -3.7 -1.8 -1.1 -2.1 -1.2 -2.0 -1.9 -0.8 -0.8
Arm predicted mass (left) 4.0 21.0 59.9 -5.7 5.0 4.9 1.9 2.0 4.4 2.5 3.6 7.1 0.0 1.1 6.6 4.8 3.4 -0.6 2.4 5.2 5.4 7.7 3.1 5.4 5.2 -6.1