TWAS hub - ZZEF1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Breast Mammary Tissue (Female)	0.1085	0.0706	4.6e-02	-0.009	NA	-0.008	NA	-0.004	7.2e-01	NA	7.0e-01	NA	4.6e-01
2	GTEx	Muscle Skeletal	0.1119	0.0426	1.5e-03	0.006	NA	0.009	NA	0.012	7.4e-02	NA	4.4e-02	NA	1.9e-02
3	GTEx	Thyroid	0.1480	0.0460	1.2e-05	0.065	NA	0.087	NA	0.083	1.1e-05	NA	3.5e-07	NA	6.6e-07
4	ROSMAP	Brain Pre-frontal Cortex	0.0683	0.0213	4.7e-07	0.062	0.052	0.055	0.052	0.057	2.1e-08	2.7e-07	1.1e-07	2.8e-07	8.1e-08
5	YFS	Blood	0.0585	0.0141	2.4e-11	0.029	0.039	0.061	0.060	0.059	9.2e-10	9.0e-13	2.3e-19	7.5e-19	1.7e-18

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1
8.2	7.1	6.6	9.6	6.7
2.6	5.6	3.4	3.6	2.0
2.2	5.5	3.2	3.6	2.1
2.8	5.5	3.5	4.7	3.5
3.9	5.3	4.4	4.5	2.9
2.9	5.3	3.7	4.8	3.6
2.8	5.2	3.1	4.6	3.3
2.9	5.2	3.8	4.5	3.2
2.5	5.1	3.8	4.2	3.4
3.0	5.1	3.1	4.6	3.3
1.0	5.0	1.5	4.3	2.8
3.3	5.0	3.5	4.4	3.3
2.9	5.0	3.6	4.4	3.5
3.1	4.9	3.6	4.5	3.8
2.6	4.8	2.8	4.6	3.5
3.1	4.8	3.3	4.2	2.9
5.6	4.7	3.2	4.5	2.3
2.4	4.7	3.3	4.1	3.3
2.4	4.7	3.2	4.2	3.6
2.9	4.7	3.2	3.3	1.9
2.6	4.6	3.2	4.1	3.0
3.4	4.4	3.5	5.2	4.1
1.9	4.2	2.6	2.9	2.0
2.0	4.2	3.2	3.3	2.9
1.8	4.1	2.5	3.7	2.9
1.4	4.1	3.0	3.4	3.1
2.0	4.1	1.6	2.9	2.1
3.6	4.1	3.6	5.5	4.0
2.2	4.1	3.1	3.5	3.2
3.1	4.0	4.3	4.8	4.2
1.6	4.0	2.4	3.5	3.0
2.7	3.9	2.4	3.3	1.7
1.0	3.9	1.6	3.5	2.2
2.7	3.9	3.8	3.2	2.1
1.7	3.9	3.2	3.3	3.2
1.9	3.7	3.2	3.2	3.4
2.1	3.7	2.7	2.9	1.6
1.7	3.6	3.3	3.3	2.8
1.4	3.6	3.0	2.8	2.8
1.3	3.6	3.0	2.8	2.9
1.9	3.6	3.1	3.1	3.3
1.4	3.5	1.9	2.6	1.8
1.3	3.4	2.9	2.8	1.3
1.3	3.4	2.9	2.9	3.0
1.3	3.4	2.8	2.8	2.9
1.1	3.4	1.8	3.2	2.3
2.4	3.2	1.4	2.3	-0.1
0.8	3.1	2.8	2.6	2.8
1.2	3.1	1.7	1.6	0.0
0.8	3.1	2.7	2.6	2.8
2.6	3.1	3.2	2.9	2.1
2.3	3.0	1.5	2.3	0.2
3.3	3.0	3.6	3.4	2.0
1.1	3.0	2.2	2.6	1.8
2.2	2.8	2.5	0.7	-0.0
1.8	2.7	0.8	1.7	0.7
0.5	2.6	1.2	2.7	2.1
0.8	2.6	2.0	2.0	1.2
1.3	2.6	2.5	1.3	0.1
0.6	2.5	2.4	2.3	2.5
2.1	2.5	3.3	4.1	3.8
0.5	2.5	2.4	2.2	2.4
2.4	2.4	2.8	1.2	0.4
1.0	2.4	0.5	2.4	1.1
1.9	2.3	2.0	0.7	-0.4
0.5	2.3	1.9	1.8	1.6
0.8	2.3	0.2	0.9	0.1
1.1	2.2	1.6	2.9	2.5
2.4	2.2	1.8	2.3	1.7
0.0	2.2	0.2	0.4	-0.4
0.8	2.1	0.0	1.1	0.1
0.4	2.1	-0.4	1.4	0.8
-0.2	2.1	0.1	0.6	-0.7
1.2	2.1	0.2	1.2	0.4
0.7	2.1	0.6	1.7	0.9
0.3	2.0	1.6	2.6	1.9
0.9	2.0	0.2	1.6	1.9
2.6	2.0	1.1	1.8	0.1
1.1	1.9	2.1	1.7	0.2
2.5	1.9	1.2	2.8	2.0
2.2	1.9	3.0	1.9	0.7
2.0	1.9	0.9	1.5	0.9
0.4	1.8	2.1	1.1	0.8
0.9	1.8	0.6	0.8	0.0
1.6	1.8	1.9	2.1	1.0
1.3	1.7	0.6	1.2	0.1
1.0	1.7	0.4	1.5	1.3
0.6	1.7	0.7	1.2	1.0
0.7	1.7	0.7	1.7	1.1
0.7	1.7	0.5	-0.5	-1.6
1.7	1.6	3.5	2.6	3.6
2.4	1.6	0.6	2.2	1.0
0.9	1.6	0.9	1.5	0.7
0.5	1.6	0.8	0.9	0.3
0.8	1.6	0.6	0.5	-0.2
1.5	1.6	0.4	1.1	0.6
1.2	1.6	1.1	0.7	0.8
0.5	1.5	1.9	2.7	1.9
1.0	1.5	3.2	2.7	3.8
1.0	1.5	-1.0	0.2	-0.5
0.2	1.5	-1.0	0.4	0.8
0.4	1.4	-2.2	0.2	0.4
2.3	1.4	1.5	0.6	-0.1
1.3	1.4	0.9	0.8	0.8
0.9	1.4	-0.4	1.2	0.9
2.0	1.3	-0.4	0.8	-0.0
1.2	1.3	0.7	0.9	0.3
0.8	1.3	-0.2	1.3	0.9
-0.6	1.3	-0.1	-0.7	-1.7
0.2	1.3	1.3	0.5	-0.0
1.4	1.3	0.7	1.8	0.5
-0.1	1.3	0.7	-1.0	-1.4
0.4	1.3	0.8	1.5	1.2
0.5	1.2	0.4	1.2	1.0
0.6	1.2	1.3	2.1	1.8
0.3	1.2	0.9	0.5	0.1
-0.1	1.2	0.4	0.1	0.1
1.1	1.1	0.0	-0.4	-0.6
0.2	1.1	0.2	1.6	1.2
1.7	1.1	1.1	2.6	1.7
-0.7	1.1	0.4	1.7	2.2
0.7	1.1	0.5	1.4	1.6
0.8	1.1	0.5	-0.2	-0.1
-0.3	1.1	0.9	1.7	1.4
0.9	1.1	0.3	1.8	1.8
0.5	1.1	1.4	0.8	0.9
0.1	1.1	0.8	-0.1	0.1
-0.4	1.1	-0.5	0.6	0.8
1.4	1.0	2.0	1.0	1.1
1.3	1.0	0.4	0.5	0.1
1.4	1.0	0.6	0.1	-0.7
0.6	1.0	0.5	0.8	0.1
1.8	1.0	-0.5	0.6	-0.5
0.6	1.0	-0.5	-0.6	-1.3
0.7	1.0	1.5	1.5	1.2
0.7	1.0	-0.1	0.7	0.4
1.5	1.0	1.1	1.4	0.7
0.4	1.0	-0.4	1.1	1.1
0.7	1.0	1.7	0.7	0.6
1.6	0.9	0.9	0.9	-0.1
-0.8	0.9	-2.4	-0.6	-1.4
0.5	0.9	0.2	0.9	0.7
0.2	0.9	-0.3	1.5	1.9
0.2	0.9	1.5	0.5	0.4
1.0	0.9	-0.4	-0.5	-2.1
-0.4	0.8	-0.1	0.6	0.4
0.5	0.8	2.5	0.6	-0.5
0.5	0.8	0.0	-0.1	-0.0
0.6	0.8	0.6	0.2	-0.1
0.9	0.7	0.6	1.2	0.5
0.3	0.7	0.4	-0.1	-0.6
0.6	0.7	-0.4	-0.1	-0.7
0.1	0.7	0.9	-0.7	-0.7
0.1	0.7	0.1	-0.9	-1.6
-0.0	0.7	0.4	-0.3	0.7
0.2	0.7	1.1	0.5	0.3
0.4	0.6	2.9	2.2	2.3
0.0	0.6	0.7	0.6	-0.3
0.8	0.6	0.4	-0.6	-1.2
2.0	0.6	1.2	1.8	1.5
-1.3	0.6	-0.6	-0.7	-1.9
-0.8	0.6	-1.7	-0.4	-1.4
-0.7	0.6	-0.6	-0.2	-1.4
1.4	0.6	0.9	0.0	-1.3
-0.1	0.6	1.3	0.7	0.4
0.2	0.6	-0.5	0.9	1.1
-1.3	0.6	0.4	-0.6	-0.3
-0.1	0.5	0.6	0.2	0.0
-1.9	0.5	0.9	-0.8	0.1
-0.7	0.5	0.0	1.7	2.1
1.3	0.5	1.4	1.6	0.9
1.5	0.5	0.7	1.4	0.1
1.7	0.4	0.9	1.6	1.3
0.7	0.4	-1.1	1.2	1.3
-0.2	0.4	-0.1	-0.5	-0.6
0.3	0.4	0.1	0.4	0.6
0.2	0.4	0.3	-0.8	-0.5
-1.1	0.4	-0.1	0.6	1.3
2.1	0.4	2.0	2.0	1.9
-0.9	0.4	-0.5	0.1	0.1
1.1	0.4	0.7	1.3	1.3
-0.6	0.4	-1.7	-0.5	-0.7
0.7	0.4	-1.3	0.0	-0.8
-0.4	0.3	1.1	-0.6	-1.3
0.3	0.3	-0.3	-0.5	-1.3
0.1	0.3	-1.0	-0.2	0.4
-1.1	0.3	0.2	1.3	1.8
0.4	0.3	0.4	1.1	0.3
-0.7	0.2	-0.7	-0.8	-0.9
0.2	0.2	0.6	0.5	0.7
0.2	0.2	-0.8	-0.5	-0.6
0.2	0.2	-1.0	0.3	0.2
-1.1	0.2	-1.2	-1.4	-1.5
0.4	0.2	1.4	0.6	0.6
-0.1	0.2	-0.9	-1.4	-2.2
-0.2	0.2	-0.2	-0.9	-1.2
0.7	0.2	-0.4	-0.3	-0.4
0.9	0.2	-0.2	0.4	-0.2
-0.0	0.1	1.1	-0.7	-0.4
0.2	0.1	1.2	0.1	-0.8
-1.4	0.1	1.1	0.2	0.4
0.0	0.1	-0.7	-0.3	-0.2
-0.8	0.1	-0.5	-0.5	-1.5
-0.3	0.1	-0.1	-0.2	0.1
-0.5	0.1	0.8	-0.3	0.1
0.0	0.0	0.0	-0.8	-1.0
0.0	0.0	0.0	0.0	0.0
0.3	0.0	0.5	0.9	0.2
-0.4	0.0	0.5	-0.7	-0.9
0.5	-0.0	1.0	0.6	0.5
-2.6	0.0	-1.0	-1.6	-0.8
-0.1	-0.0	-0.5	0.4	0.5
-2.3	-0.1	-2.7	-1.5	-1.6
-2.0	-0.1	-1.0	-0.7	-0.0
-0.2	-0.1	-1.1	-0.5	-0.8
-0.0	-0.1	1.5	0.2	0.1
-0.2	-0.1	-0.1	-1.4	-2.6
0.1	-0.1	0.1	0.3	0.8
0.6	-0.2	-0.8	-1.5	-1.5
-1.8	-0.2	-2.1	-1.3	-0.6
-0.5	-0.2	-0.7	0.5	1.6
-0.2	-0.2	-1.9	-0.3	-1.0
0.5	-0.2	0.3	0.5	0.0
-1.7	-0.2	-1.7	-1.6	-1.4
1.1	-0.2	0.7	0.5	0.7
-0.4	-0.2	-2.0	-0.8	-0.7
-0.1	-0.2	0.6	-0.4	-1.0
0.0	-0.3	0.7	-0.5	-0.8
1.0	-0.3	0.5	0.3	0.8
0.1	-0.3	-1.5	-0.2	-0.7
0.3	-0.3	-0.4	0.2	-0.0
-1.2	-0.3	-1.2	-1.1	-1.2
0.4	-0.3	-0.5	0.5	-0.1
-0.8	-0.3	-0.3	0.6	0.7
-0.6	-0.3	-1.4	-1.0	-1.7
0.3	-0.3	-1.0	-0.2	-0.6
-0.7	-0.4	-0.7	-1.9	-1.7
-0.0	-0.4	-0.5	-1.4	-1.6
-1.4	-0.4	-2.2	-1.3	-0.7
-0.7	-0.4	-1.9	-0.9	-1.0
-1.1	-0.4	-1.0	-1.9	-2.4
-0.2	-0.4	-0.3	-0.6	-0.2
0.1	-0.4	0.6	-0.5	-0.6
-0.2	-0.4	-0.0	-0.9	-0.7
-0.5	-0.5	-1.2	-0.7	-1.4
-1.6	-0.5	-1.9	-0.8	0.1
-2.1	-0.5	0.5	-1.1	-1.2
-1.5	-0.5	-0.5	-0.8	-1.3
-1.2	-0.5	-1.6	-0.8	-0.3
-0.0	-0.5	0.6	0.4	1.2
-0.9	-0.6	-1.3	-1.8	-1.9
-0.7	-0.6	-1.1	-1.0	-0.9
-0.8	-0.6	-0.9	-0.8	-0.7
-1.1	-0.6	-1.0	-1.2	-0.5
-1.4	-0.6	-1.0	-1.2	-0.7
-0.1	-0.6	0.8	0.1	-0.1
-0.6	-0.6	-1.5	-1.2	-1.3
-1.7	-0.6	-1.6	-1.3	-1.7
0.6	-0.6	-0.7	-1.4	-2.1
-1.1	-0.7	-1.9	-0.6	0.9
0.5	-0.7	-1.3	-0.9	-1.1
-0.7	-0.7	-0.7	-0.6	-0.3
0.3	-0.7	2.1	0.1	0.3
-0.6	-0.7	-2.5	-1.1	-0.8
-0.1	-0.7	-2.4	-0.6	-0.8
-1.0	-0.7	0.5	-0.5	-0.6
-1.2	-0.7	-0.8	-1.2	-0.2
-1.4	-0.7	-2.1	-1.6	-0.7
-1.4	-0.7	-1.1	-2.0	-0.8
0.8	-0.8	0.3	0.9	1.2
-0.9	-0.8	-1.1	-1.2	-1.2
0.1	-0.8	0.5	-0.4	-0.1
-0.1	-0.8	-0.2	-1.1	-0.8
-1.0	-0.9	-1.4	-2.5	-1.8
-0.7	-0.9	-0.7	-1.9	-1.7
0.2	-0.9	-0.5	-0.4	-0.0
-0.4	-0.9	-1.0	-1.0	-0.9
1.6	-0.9	0.3	0.7	1.0
0.6	-0.9	0.2	-1.0	-1.3
-1.6	-0.9	-0.2	-1.3	-1.1
0.3	-0.9	0.4	0.4	0.3
-0.6	-0.9	-0.4	-1.2	-0.7
-1.4	-1.0	-1.3	-3.1	-3.6
0.1	-1.0	-0.8	0.7	0.9
-1.1	-1.0	-2.0	-0.5	0.4
0.0	-1.0	-0.6	-1.5	-0.8
-1.6	-1.0	-1.5	-1.1	-0.6
0.2	-1.0	0.0	-1.1	-1.1
-0.2	-1.1	-0.6	-0.7	-0.7
-0.1	-1.1	-1.8	-1.0	-0.6
0.2	-1.1	-0.5	1.1	1.4
-0.3	-1.1	0.0	-0.7	-0.5
-1.1	-1.1	-1.1	-0.6	0.1
-0.7	-1.2	-1.2	-2.2	-1.5
-1.1	-1.2	-1.6	-1.6	-0.8
-0.7	-1.2	-1.3	-1.6	-1.2
-1.3	-1.2	-1.8	-1.2	-0.3
-1.2	-1.2	-0.5	-0.6	0.2
-1.8	-1.2	-2.7	-1.6	-1.3
-0.0	-1.2	-0.9	-1.3	-0.9
0.4	-1.2	0.3	-0.5	0.1
0.9	-1.3	0.6	-0.3	-0.7
-1.2	-1.3	-1.3	-1.5	-0.8
-1.2	-1.4	-2.3	-1.4	-0.2
-0.9	-1.4	0.7	-1.3	-1.7
-2.0	-1.4	-2.5	-1.6	-0.9
-1.5	-1.4	-0.1	-1.9	-2.0
-1.4	-1.4	-1.0	-1.6	-0.8
0.0	-1.6	-1.3	-2.3	-3.0
-0.7	-1.6	-0.5	-1.1	0.4
-2.2	-1.6	-0.5	-2.4	-1.5
-2.6	-1.6	0.2	-0.9	0.0
-2.0	-1.6	-0.9	-1.4	0.5
-1.6	-1.7	-0.6	-0.8	1.9
-0.6	-1.7	-1.2	-0.5	0.7
-0.2	-1.7	-1.8	-0.2	-0.1
-1.1	-1.8	-1.9	-1.4	-0.8
-1.8	-1.8	-1.0	-1.1	-0.3
-0.9	-1.8	-1.4	-1.9	-1.6
-2.5	-1.9	-1.6	-2.4	-1.4
-2.7	-1.9	-1.8	-2.2	-1.9
-2.8	-1.9	-1.7	-3.0	-2.2
-2.3	-1.9	-0.9	-1.5	-0.8
-0.4	-1.9	-1.0	-2.7	-2.1
-1.3	-2.0	-1.3	-1.3	0.2
-0.5	-2.0	-1.3	-1.3	-0.5
-0.8	-2.0	-1.0	-1.9	-1.1
-1.3	-2.2	-1.6	-2.4	-2.3
-2.8	-2.2	-2.7	-3.8	-3.3
-2.2	-2.4	-1.7	-1.4	0.9
-1.6	-2.4	-1.7	-2.6	-1.3
-1.2	-2.4	-1.5	-1.9	-2.1
-0.8	-2.4	0.3	-1.1	-0.7
-3.3	-2.5	-4.7	-4.5	-3.1
-0.3	-2.5	-2.3	-0.8	-0.7
-1.5	-2.6	-1.4	-3.2	-2.3
-0.8	-2.7	-1.7	-2.5	-1.3
-2.4	-2.8	-2.6	-3.8	-2.6
-0.7	-2.9	-1.0	-2.7	-1.4
-2.0	-3.8	-2.4	-3.0	-2.3
-4.5	-4.0	-4.8	-6.3	-4.7
-1.5	-4.8	-2.6	-3.1	-2.1

Hub : Genes

ZZEF1

Models

Trait associations