TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Bipolar Disorder or Schizophrenia
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chr3:63,121,945-64,546,545
Best TWAS P=2.2e-09 · Best GWAS P=4.98e-09 conditioned to 0.306
63.2M
63.4M
63.6M
63.8M
64M
64.2M
64.4M
64.6M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
THOC7
0.10
0.10
lasso
5
0.06
2.7e-08
5.8
-6.0
2.2e-09
-0.90
0.00
1.00
TRUE
3
ROSMAP
Brain Pre-frontal Cortex
THOC7
0.18
0.15
bslmm
599
0.16
2.1e-20
5.8
-5.7
1.2e-08
-0.82
0.00
1.00
FALSE
2
GTEx
Brain Cerebellum
THOC7
0.27
0.10
lasso
3
0.12
1.9e-04
5.6
-5.5
3.7e-08
-0.84
0.02
0.93
FALSE