Best TWAS P=2.2e-09 · Best GWAS P=4.98e-09 conditioned to 0.306
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | THOC7 | 0.10 | 0.10 | lasso | 5 | 0.06 | 2.7e-08 | 5.8 | -6.0 | 2.2e-09 | -0.90 | 0.00 | 1.00 | TRUE |
| 2 | GTEx | Brain Cerebellum | THOC7 | 0.27 | 0.10 | lasso | 3 | 0.12 | 1.9e-04 | 5.6 | -5.5 | 3.7e-08 | -0.84 | 0.02 | 0.93 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | THOC7 | 0.18 | 0.15 | bslmm | 599 | 0.16 | 2.1e-20 | 5.8 | -5.7 | 1.2e-08 | -0.82 | 0.00 | 1.00 | FALSE |