TWAS
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Traits
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Traits
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Bipolar Disorder or Schizophrenia
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chr5:44,129,083-45,516,364
Best TWAS P=6.92e-08 · Best GWAS P=1.21e-08 conditioned to 0.0259
44.2M
44.4M
44.6M
44.8M
45M
45.2M
45.4M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Artery Tibial
RP11-53O19.3
0.03
0.02
enet
10
0.03
1.3e-03
4.7
-5.4
6.9e-08
-0.82
0.29
0.57
TRUE
3
The Cancer Genome Atlas
Breast Invasive Carcinoma
MRPS30
0.04
0.04
enet
4
0.04
1.5e-09
4.6
5.3
9.7e-08
0.74
0.02
0.96
FALSE
2
GTEx
Nerve Tibial
RP11-53O19.3
0.08
0.14
enet
15
0.13
1.3e-09
4.6
-5.3
1.1e-07
-0.80
0.40
0.59
FALSE