Best TWAS P=6.92e-08 · Best GWAS P=1.21e-08 conditioned to 0.0259
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | RP11-53O19.3 | 0.03 | 0.02 | enet | 10 | 0.03 | 1.3e-03 | 4.7 | -5.4 | 6.9e-08 | -0.82 | 0.29 | 0.57 | TRUE |
| 2 | GTEx | Nerve Tibial | RP11-53O19.3 | 0.08 | 0.14 | enet | 15 | 0.13 | 1.3e-09 | 4.6 | -5.3 | 1.1e-07 | -0.80 | 0.40 | 0.59 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | MRPS30 | 0.04 | 0.04 | enet | 4 | 0.04 | 1.5e-09 | 4.6 | 5.3 | 9.7e-08 | 0.74 | 0.02 | 0.96 | FALSE |