[Hub]/) : Traits : Crohns Disease (2017) : ← →

chr16:10,646,170-12,426,645

Best TWAS P=8.43e-11 · Best GWAS P=2.81e-08 conditioned to 0.0906

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RMI2 0.10 0.06 lasso 5 0.07 1.9e-06 -5.3 -5.8 6.1e-09 0.93 0.02 0.98 FALSE
2 GTEx Adipose Visceral Omentum RMI2 0.23 0.16 enet 16 0.14 6.6e-08 2.7 -5.6 1.8e-08 0.52 0.52 0.45 FALSE
3 GTEx Artery Aorta RMI2 0.30 0.11 lasso 5 0.17 1.3e-09 -5.6 -5.9 2.7e-09 0.84 0.02 0.98 FALSE
4 GTEx Artery Coronary RMI2 0.32 0.14 lasso 6 0.12 9.9e-05 -5.5 -6.5 8.4e-11 0.94 0.01 0.98 TRUE
5 GTEx Artery Tibial RMI2 0.27 0.11 enet 27 0.21 1.4e-16 -5.5 -6.0 2.2e-09 0.77 0.01 0.99 FALSE
6 GTEx Brain Caudate basal ganglia RMI2 0.46 0.22 enet 19 0.24 1.2e-07 -4.3 -5.3 1.2e-07 0.52 0.22 0.72 FALSE
7 GTEx Breast Mammary Tissue (Male) RMI2 0.32 0.15 enet 25 0.10 2.9e-03 -4.9 -5.6 2.7e-08 0.38 0.06 0.21 FALSE
8 GTEx Heart Left Ventricle RMI2 0.24 0.09 lasso 6 0.12 6.2e-07 -5.0 -5.3 1.3e-07 0.90 0.04 0.95 FALSE
9 GTEx Muscle Skeletal RMI2 0.28 0.12 lasso 11 0.20 2.1e-19 -5.3 -5.8 7.4e-09 0.85 0.02 0.98 FALSE
10 GTEx Muscle Skeletal LITAF 0.39 0.19 enet 30 0.21 1.9e-20 4.6 -5.2 1.7e-07 0.26 0.42 0.57 FALSE
11 GTEx Ovary RMI2 0.48 0.26 lasso 9 0.20 1.2e-05 -4.9 -5.8 7.0e-09 0.55 0.10 0.71 FALSE
12 GTEx Prostate RMI2 0.35 0.09 lasso 2 0.16 1.1e-04 -5.0 -5.8 7.6e-09 0.86 0.04 0.73 FALSE
13 GTEx Uterus RMI2 0.54 0.02 enet 20 0.04 6.4e-02 3.2 -6.1 8.7e-10 0.71 0.04 0.73 FALSE