[Hub]/) : Traits : Crohns Disease (2017) : ← →

chr16:10,646,170-12,426,645

Best TWAS P=8.43e-11 · Best GWAS P=2.81e-08 conditioned to 0.0906

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Artery Coronary	RMI2	0.32	0.14	lasso	6	0.12	9.9e-05	-5.5	-6.5	8.4e-11	0.94	0.01	0.98	TRUE
13	GTEx	Uterus	RMI2	0.54	0.02	enet	20	0.04	6.4e-02	3.2	-6.1	8.7e-10	0.71	0.04	0.73	FALSE
5	GTEx	Artery Tibial	RMI2	0.27	0.11	enet	27	0.21	1.4e-16	-5.5	-6.0	2.2e-09	0.77	0.01	0.99	FALSE
3	GTEx	Artery Aorta	RMI2	0.30	0.11	lasso	5	0.17	1.3e-09	-5.6	-5.9	2.7e-09	0.84	0.02	0.98	FALSE
1	GTEx	Adipose Subcutaneous	RMI2	0.10	0.06	lasso	5	0.07	1.9e-06	-5.3	-5.8	6.1e-09	0.93	0.02	0.98	FALSE
11	GTEx	Ovary	RMI2	0.48	0.26	lasso	9	0.20	1.2e-05	-4.9	-5.8	7.0e-09	0.55	0.10	0.71	FALSE
9	GTEx	Muscle Skeletal	RMI2	0.28	0.12	lasso	11	0.20	2.1e-19	-5.3	-5.8	7.4e-09	0.85	0.02	0.98	FALSE
12	GTEx	Prostate	RMI2	0.35	0.09	lasso	2	0.16	1.1e-04	-5.0	-5.8	7.6e-09	0.86	0.04	0.73	FALSE
2	GTEx	Adipose Visceral Omentum	RMI2	0.23	0.16	enet	16	0.14	6.6e-08	2.7	-5.6	1.8e-08	0.52	0.52	0.45	FALSE
7	GTEx	Breast Mammary Tissue (Male)	RMI2	0.32	0.15	enet	25	0.10	2.9e-03	-4.9	-5.6	2.7e-08	0.38	0.06	0.21	FALSE
6	GTEx	Brain Caudate basal ganglia	RMI2	0.46	0.22	enet	19	0.24	1.2e-07	-4.3	-5.3	1.2e-07	0.52	0.22	0.72	FALSE
8	GTEx	Heart Left Ventricle	RMI2	0.24	0.09	lasso	6	0.12	6.2e-07	-5.0	-5.3	1.3e-07	0.90	0.04	0.95	FALSE
10	GTEx	Muscle Skeletal	LITAF	0.39	0.19	enet	30	0.21	1.9e-20	4.6	-5.2	1.7e-07	0.26	0.42	0.57	FALSE