[Hub]/) : Traits : Blood Eosinophil Count : ← →

chr7:127,878,155-129,284,182

Best TWAS P=8.58e-14 · Best GWAS P=5.99e-13 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Visceral Omentum	IRF5	0.16	0.08	lasso	4	0.08	8.2e-05	-7.2	-7.2	6.4e-13	0.99	0.00	1.00	FALSE
2	GTEx	Colon Transverse	IRF5	0.21	0.22	lasso	4	0.22	8.0e-11	-7.2	-7.2	5.3e-13	1.00	0.00	1.00	FALSE
3	GTEx	Esophagus Mucosa	IRF5	0.13	0.14	lasso	4	0.13	4.6e-09	-7.2	-6.9	4.0e-12	1.00	0.00	1.00	FALSE
4	GTEx	Esophagus Muscularis	IRF5	0.21	0.12	lasso	5	0.11	3.9e-07	-7.2	-7.0	2.5e-12	0.95	0.00	1.00	FALSE
5	GTEx	Nerve Tibial	IRF5	0.13	0.09	enet	10	0.07	1.2e-05	-7.2	-7.3	2.8e-13	0.95	0.00	1.00	FALSE
6	GTEx	Skin Sun Exposed Lower leg	IRF5	0.10	0.14	lasso	2	0.12	1.9e-10	-7.2	-7.3	2.1e-13	1.00	0.00	1.00	FALSE
7	GTEx	Thyroid	IRF5	0.14	0.10	enet	6	0.11	1.2e-08	-7.2	-5.2	2.0e-07	0.85	0.00	1.00	FALSE
8	GTEx	Whole Blood	IRF5	0.17	0.06	lasso	4	0.09	1.2e-08	5.6	-7.1	1.4e-12	0.91	0.00	1.00	FALSE
9	METSIM	Adipose	IRF5	0.05	0.04	lasso	7	0.04	2.2e-06	-7.2	-6.9	4.6e-12	0.95	0.00	1.00	FALSE
10	ROSMAP	Brain Pre-frontal Cortex	IRF5	0.27	0.25	bslmm	336	0.25	7.1e-32	5.8	-5.9	4.8e-09	0.68	0.94	0.06	FALSE
11	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	IRF5	0.09	0.06	blup	30	0.08	1.8e-07	5.6	-7.4	1.4e-13	0.75	0.01	0.99	FALSE
12	The Cancer Genome Atlas	Breast Invasive Carcinoma	IRF5	0.10	0.09	lasso	4	0.08	1.6e-16	-7.2	-7.0	2.4e-12	0.99	0.00	1.00	FALSE
13	The Cancer Genome Atlas	Colon Adenocarcinoma	IRF5	0.29	0.26	enet	6	0.29	3.1e-17	7.0	-7.5	8.6e-14	0.95	0.00	1.00	TRUE
14	The Cancer Genome Atlas	Glioblastoma Multiforme	IRF5	0.18	0.02	enet	8	0.04	2.4e-02	4.5	-5.9	3.0e-09	0.59	0.01	0.57	FALSE
15	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	IRF5	0.14	0.12	enet	7	0.15	1.8e-16	-7.0	-6.8	1.4e-11	0.88	0.00	1.00	FALSE
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IRF5	0.11	0.05	blup	30	0.07	2.2e-08	-7.2	-6.5	8.0e-11	0.85	0.00	1.00	FALSE
17	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	IRF5	0.09	0.04	lasso	4	0.06	2.3e-04	-7.2	-7.2	4.0e-13	0.97	0.00	1.00	FALSE
18	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	IRF5	0.17	0.09	enet	6	0.15	1.8e-07	5.4	-6.9	6.3e-12	0.81	0.02	0.98	FALSE
19	The Cancer Genome Atlas	Lung Adenocarcinoma	IRF5	0.18	0.11	enet	9	0.14	1.6e-15	-7.2	-6.2	5.7e-10	0.90	0.00	1.00	FALSE
20	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	IRF5	0.09	0.09	blup	30	0.13	3.1e-14	7.0	-6.0	2.6e-09	0.79	0.01	0.99	FALSE
21	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	IRF5	0.14	0.15	enet	6	0.14	7.0e-10	7.0	-7.2	4.8e-13	0.86	0.00	1.00	FALSE
22	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	IRF5	0.09	0.10	lasso	3	0.08	4.6e-04	7.0	-6.9	3.8e-12	0.85	0.00	0.91	FALSE
23	The Cancer Genome Atlas	Prostate Adenocarcinoma	IRF5	0.23	0.26	lasso	3	0.26	3.6e-27	7.0	-7.3	3.4e-13	0.92	0.00	1.00	FALSE
24	The Cancer Genome Atlas	Rectum Adenocarcinoma	IRF5	0.41	0.13	blup	33	0.23	3.5e-06	7.0	-6.8	1.1e-11	0.89	0.00	0.98	FALSE
25	The Cancer Genome Atlas	Thyroid Carcinoma	IRF5	0.22	0.21	enet	9	0.26	4.6e-25	7.0	-7.3	2.8e-13	0.92	0.00	1.00	FALSE