Best TWAS P=4.41e-08 · Best GWAS P=8.59e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | VPS53 | 0.09 | 0.05 | enet | 10 | 0.08 | 5.9e-10 | -5.2 | 5.3 | 1.1e-07 | -0.81 | 0.01 | 0.99 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | VPS53 | 0.29 | 0.17 | lasso | 6 | 0.28 | 9.0e-37 | -3.1 | 5.2 | 2.2e-07 | -0.66 | 0.10 | 0.88 | FALSE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | VPS53 | 0.03 | 0.04 | lasso | 1 | 0.03 | 1.1e-04 | -5.4 | 5.3 | 8.6e-08 | -1.00 | 0.00 | 0.98 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FAM57A | 0.17 | 0.16 | enet | 8 | 0.20 | 8.6e-21 | -5.3 | 5.4 | 5.6e-08 | -0.94 | 0.00 | 0.99 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | GEMIN4 | 0.05 | 0.06 | lasso | 4 | 0.05 | 3.6e-06 | -5.4 | 5.5 | 4.4e-08 | -0.99 | 0.00 | 1.00 | TRUE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | VPS53 | 0.13 | 0.15 | lasso | 4 | 0.15 | 7.2e-16 | -5.3 | 5.2 | 1.9e-07 | -0.99 | 0.00 | 0.99 | FALSE |