Best TWAS P=1.42e-20 · Best GWAS P=1.42e-20 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | IFNAR2 | 0.13 | 0.06 | enet | 23 | 0.09 | 1.6e-10 | -4.6 | 5.8 | 8.4e-09 | 0.06 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Colon Transverse | IFNAR2 | 0.28 | 0.15 | lasso | 3 | 0.21 | 1.8e-10 | 5.0 | -5.2 | 1.6e-07 | 0.06 | 1.00 | 0.00 | FALSE |
| 3 | GTEx | Esophagus Mucosa | IFNAR2 | 0.39 | 0.21 | lasso | 7 | 0.21 | 4.8e-14 | 4.9 | -5.3 | 1.2e-07 | 0.05 | 1.00 | 0.00 | FALSE |
| 4 | GTEx | Esophagus Mucosa | IL10RB-AS1 | 0.31 | 0.23 | lasso | 4 | 0.24 | 8.4e-16 | 5.0 | -5.4 | 5.9e-08 | 0.05 | 1.00 | 0.00 | FALSE |
| 5 | GTEx | Skin Sun Exposed Lower leg | IFNAR2 | 0.25 | 0.19 | lasso | 5 | 0.22 | 7.7e-18 | -4.6 | -5.2 | 2.3e-07 | 0.06 | 1.00 | 0.00 | FALSE |
| 6 | GTEx | Skin Sun Exposed Lower leg | IL10RB-AS1 | 0.17 | 0.14 | lasso | 5 | 0.16 | 7.8e-13 | 7.0 | -6.0 | 1.6e-09 | 0.08 | 1.00 | 0.00 | TRUE |
| 7 | GTEx | Testis | IL10RB-AS1 | 0.18 | 0.03 | lasso | 4 | 0.02 | 3.0e-02 | 4.9 | -5.3 | 1.1e-07 | 0.03 | 0.19 | 0.04 | FALSE |
| 8 | METSIM | Adipose | OLIG1 | 0.08 | 0.05 | lasso | 6 | 0.06 | 5.4e-09 | 9.3 | 9.0 | 2.0e-19 | 0.92 | 0.00 | 1.00 | FALSE |
| 9 | NTR | Blood | OLIG1 | 0.05 | 0.07 | lasso | 1 | 0.07 | 2.3e-20 | 9.3 | 9.3 | 1.4e-20 | 1.00 | 0.00 | 1.00 | TRUE |
| 10 | NTR | Blood | OLIG2 | 0.03 | 0.02 | lasso | 4 | 0.02 | 7.0e-07 | 8.5 | 8.8 | 1.5e-18 | 0.89 | 0.01 | 0.99 | FALSE |
| 11 | YFS | Blood | OLIG1 | 0.23 | 0.16 | enet | 34 | 0.19 | 1.8e-59 | 9.3 | 7.6 | 2.6e-14 | 0.91 | 0.00 | 1.00 | FALSE |