[Hub]/) : Traits : Blood Eosinophil Count :

chr21:33,710,324-35,336,884

Best TWAS P=1.42e-20 · Best GWAS P=1.42e-20 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex IFNAR2 0.13 0.06 enet 23 0.09 1.6e-10 -4.6 5.8 8.4e-09 0.06 1.00 0.00 FALSE
2 GTEx Colon Transverse IFNAR2 0.28 0.15 lasso 3 0.21 1.8e-10 5.0 -5.2 1.6e-07 0.06 1.00 0.00 FALSE
3 GTEx Esophagus Mucosa IFNAR2 0.39 0.21 lasso 7 0.21 4.8e-14 4.9 -5.3 1.2e-07 0.05 1.00 0.00 FALSE
4 GTEx Esophagus Mucosa IL10RB-AS1 0.31 0.23 lasso 4 0.24 8.4e-16 5.0 -5.4 5.9e-08 0.05 1.00 0.00 FALSE
5 GTEx Skin Sun Exposed Lower leg IFNAR2 0.25 0.19 lasso 5 0.22 7.7e-18 -4.6 -5.2 2.3e-07 0.06 1.00 0.00 FALSE
6 GTEx Skin Sun Exposed Lower leg IL10RB-AS1 0.17 0.14 lasso 5 0.16 7.8e-13 7.0 -6.0 1.6e-09 0.08 1.00 0.00 TRUE
7 GTEx Testis IL10RB-AS1 0.18 0.03 lasso 4 0.02 3.0e-02 4.9 -5.3 1.1e-07 0.03 0.19 0.04 FALSE
8 METSIM Adipose OLIG1 0.08 0.05 lasso 6 0.06 5.4e-09 9.3 9.0 2.0e-19 0.92 0.00 1.00 FALSE
9 NTR Blood OLIG1 0.05 0.07 lasso 1 0.07 2.3e-20 9.3 9.3 1.4e-20 1.00 0.00 1.00 TRUE
10 NTR Blood OLIG2 0.03 0.02 lasso 4 0.02 7.0e-07 8.5 8.8 1.5e-18 0.89 0.01 0.99 FALSE
11 YFS Blood OLIG1 0.23 0.16 enet 34 0.19 1.8e-59 9.3 7.6 2.6e-14 0.91 0.00 1.00 FALSE