Best TWAS P=1.15e-07 · Best GWAS P=3.29e-10 conditioned to 0.000706
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Ovary | UBE2E3 | 0.25 | 0.09 | lasso | 8 | 0.10 | 1.5e-03 | 5.73 | -5.3 | 1.1e-07 | -0.86 | 0.06 | 0.66 | TRUE |
2 | GTEx | Skin Not Sun Exposed Suprapubic | UBE2E3 | 0.25 | 0.06 | enet | 39 | 0.12 | 2.5e-07 | -0.91 | -5.3 | 1.5e-07 | -0.66 | 0.09 | 0.91 | FALSE |