Best TWAS P=7.01e-12 · Best GWAS P=7.74e-11 conditioned to 0.151
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Tibial | UBE2F | 0.27 | 0.15 | lasso | 7 | 0.17 | 4.6e-13 | -6.2 | -5.7 | 1.1e-08 | 0.81 | 0.01 | 0.99 | FALSE |
2 | GTEx | Lung | UBE2F | 0.11 | 0.05 | lasso | 5 | 0.03 | 2.8e-03 | -5.2 | -5.2 | 1.7e-07 | 0.73 | 0.05 | 0.93 | FALSE |
3 | GTEx | Whole Blood | UBE2F | 0.17 | 0.14 | lasso | 6 | 0.12 | 2.4e-11 | -6.2 | -6.0 | 2.1e-09 | 0.81 | 0.01 | 0.99 | FALSE |
4 | METSIM | Adipose | UBE2F | 0.05 | 0.04 | lasso | 4 | 0.03 | 1.4e-05 | -6.2 | -6.2 | 7.5e-10 | 0.86 | 0.01 | 0.99 | FALSE |
5 | YFS | Blood | UBE2F | 0.18 | 0.16 | bslmm | 510 | 0.18 | 1.6e-55 | -6.2 | -6.9 | 7.0e-12 | 0.83 | 0.01 | 0.99 | TRUE |