[Hub]/) : Traits : HDL Cholesterol : ← →

chr2:84,849,386-86,275,985

Best TWAS P=8.93e-08 · Best GWAS P=1.01e-07 conditioned to 0.138

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Cells Transformed fibroblasts	TGOLN2	0.22	0.26	enet	15	0.27	2.4e-20	-5.2	-5.2	1.6e-07	0.97	0.02	0.98	FALSE
2	GTEx	Esophagus Mucosa	TGOLN2	0.17	0.19	enet	15	0.18	3.0e-12	-5.1	-5.2	1.7e-07	0.97	0.02	0.98	FALSE
3	GTEx	Esophagus Muscularis	AC093162.5	0.14	0.09	lasso	2	0.06	1.3e-04	-5.3	5.3	1.2e-07	-0.97	0.01	0.98	FALSE
4	GTEx	Lung	TGOLN2	0.07	0.04	enet	9	0.04	6.4e-04	5.0	-5.2	1.7e-07	0.94	0.02	0.98	FALSE
5	GTEx	Stomach	TGOLN2	0.20	0.11	enet	14	0.11	5.4e-06	-5.2	-5.2	1.7e-07	0.93	0.02	0.98	FALSE
6	GTEx	Whole Blood	RETSAT	0.13	0.08	lasso	5	0.14	8.0e-13	-4.5	5.3	8.9e-08	-0.85	0.03	0.97	TRUE
7	GTEx	Whole Blood	AC093162.5	0.11	0.03	lasso	2	0.01	4.0e-02	-5.3	5.3	1.1e-07	-0.97	0.01	0.98	FALSE
8	NTR	Blood	RETSAT	0.07	0.09	enet	21	0.09	2.9e-28	-5.2	5.1	2.9e-07	-0.97	0.01	0.98	FALSE
9	The Cancer Genome Atlas	Breast Invasive Carcinoma	TGOLN2	0.05	0.10	lasso	5	0.11	5.5e-21	-5.2	-5.3	1.0e-07	0.97	0.01	0.98	FALSE
10	The Cancer Genome Atlas	Colon Adenocarcinoma	TGOLN2	0.26	0.18	enet	14	0.15	5.1e-09	-5.2	-5.2	2.3e-07	0.89	0.02	0.98	FALSE
11	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TGOLN2	0.13	0.18	enet	18	0.20	1.5e-22	-5.3	-5.3	9.2e-08	0.97	0.01	0.99	FALSE
12	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TGOLN2	0.05	0.10	lasso	1	0.09	1.1e-10	-5.2	-5.2	2.1e-07	0.97	0.02	0.98	FALSE
13	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	TGOLN2	0.09	0.09	lasso	9	0.08	2.8e-05	-5.2	-5.2	2.5e-07	0.99	0.02	0.98	FALSE
14	The Cancer Genome Atlas	Brain Lower Grade Glioma	TGOLN2	0.02	0.02	enet	9	0.02	7.1e-04	5.0	-5.2	2.4e-07	0.96	0.02	0.93	FALSE
15	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	TGOLN2	0.06	0.09	lasso	2	0.08	8.6e-10	-5.3	-5.3	1.0e-07	1.00	0.01	0.99	FALSE
16	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	TGOLN2	0.18	0.16	lasso	6	0.16	3.5e-11	-5.3	-5.3	1.1e-07	1.00	0.01	0.99	FALSE
17	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	RETSAT	0.07	0.04	blup	56	0.05	4.8e-03	-4.1	5.2	2.6e-07	-0.90	0.03	0.65	FALSE
18	The Cancer Genome Atlas	Stomach Adenocarcinoma	TGOLN2	0.09	0.08	lasso	9	0.08	1.1e-06	-5.3	-5.3	1.1e-07	0.99	0.02	0.98	FALSE