Best TWAS P=8.09e-21 · Best GWAS P=1.77e-22 conditioned to 0.00228
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | MPDZ | 0.30 | 0.35 | enet | 28 | 0.34 | 4.3e-26 | -9.8 | 9.4 | 8.1e-21 | -0.9 | 0.00 | 1.00 | TRUE |
2 | GTEx | Lung | MPDZ | 0.23 | 0.08 | lasso | 4 | 0.16 | 3.0e-12 | -1.5 | 8.0 | 1.3e-15 | -0.6 | 0.01 | 0.99 | FALSE |
3 | GTEx | Nerve Tibial | MPDZ | 0.21 | 0.15 | enet | 23 | 0.22 | 2.1e-15 | -9.8 | 8.1 | 7.3e-16 | -0.8 | 0.00 | 1.00 | FALSE |