Best TWAS P=5.07e-08 · Best GWAS P=9.78e-08 conditioned to 1.19e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Frontal Cortex BA9 | C9orf72 | 0.35 | 0.07 | lasso | 8 | 0.16 | 6.5e-05 | -3.4 | -5.5 | 5.1e-08 | 0.09 | 0.20 | 0.10 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | C9orf72 | 0.15 | 0.02 | enet | 25 | 0.04 | 2.0e-04 | -3.0 | -5.3 | 9.7e-08 | 0.05 | 0.68 | 0.11 | FALSE |