Best TWAS P=1.49e-07 · Best GWAS P=2.18e-07 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | STOX1 | 0.18 | 0.14 | enet | 13 | 0.10 | 3.6e-06 | -5.0 | -5.2 | 2.6e-07 | 0.96 | 0.01 | 0.99 | FALSE |
2 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | STOX1 | 0.12 | 0.15 | lasso | 3 | 0.15 | 1.6e-12 | -5.1 | -5.2 | 2.6e-07 | 1.00 | 0.00 | 1.00 | FALSE |
3 | The Cancer Genome Atlas | Colon Adenocarcinoma | STOX1 | 0.20 | 0.14 | lasso | 2 | 0.13 | 6.8e-08 | -5.1 | -5.2 | 2.1e-07 | 0.90 | 0.00 | 1.00 | FALSE |
4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | STOX1 | 0.23 | 0.27 | lasso | 8 | 0.27 | 7.3e-30 | -5.1 | -5.2 | 2.2e-07 | 0.96 | 0.00 | 1.00 | FALSE |
5 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | STOX1 | 0.06 | 0.05 | lasso | 2 | 0.05 | 1.5e-06 | -5.1 | -5.2 | 2.4e-07 | 0.93 | 0.00 | 1.00 | FALSE |
6 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | STOX1 | 0.49 | 0.35 | blup | 51 | 0.40 | 9.6e-18 | -5.1 | -5.1 | 2.7e-07 | 0.88 | 0.00 | 1.00 | FALSE |
7 | The Cancer Genome Atlas | Prostate Adenocarcinoma | STOX1 | 0.25 | 0.21 | enet | 10 | 0.21 | 6.3e-22 | -5.1 | -5.2 | 2.3e-07 | 0.96 | 0.00 | 1.00 | FALSE |
8 | The Cancer Genome Atlas | Stomach Adenocarcinoma | STOX1 | 0.23 | 0.20 | lasso | 4 | 0.19 | 4.8e-14 | -5.1 | -5.2 | 1.5e-07 | 0.98 | 0.00 | 1.00 | TRUE |