Best TWAS P=4.83e-12 · Best GWAS P=6.89e-14 conditioned to 0.00197
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | HLF | 0.05 | 0.04 | lasso | 5 | 0.04 | 1.4e-05 | 5.8 | -6.1 | 9.0e-10 | -0.02 | 0.00 | 1.00 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | HLF | 0.25 | 0.20 | enet | 18 | 0.23 | 4.3e-13 | 6.4 | -6.4 | 1.3e-10 | -0.01 | 0.00 | 1.00 | TRUE |
| 3 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | STXBP4 | 0.07 | 0.04 | lasso | 3 | 0.05 | 1.4e-04 | -7.3 | -6.9 | 4.8e-12 | 0.88 | 0.01 | 0.97 | TRUE |
| 4 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | STXBP4 | 0.11 | 0.04 | blup | 101 | 0.07 | 7.6e-04 | -7.3 | -6.3 | 2.2e-10 | 0.75 | 0.02 | 0.72 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | STXBP4 | 0.06 | 0.00 | blup | 101 | 0.04 | 1.2e-04 | -4.7 | -6.4 | 2.1e-10 | 0.80 | 0.04 | 0.80 | FALSE |