Best TWAS P=6.7e-08 · Best GWAS P=5.73e-07 conditioned to 0.0618
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | PPP1R13B | 0.04 | 0.02 | enet | 14 | 0.02 | 0.00132 | 4.6 | -5.4 | 6.7e-08 | -0.67 | 0.05 | 0.87 | TRUE |
2 | GTEx | Small Intestine Terminal Ileum | ZFYVE21 | 0.16 | 0.10 | lasso | 2 | 0.13 | 0.00077 | 4.7 | 5.3 | 1.1e-07 | 0.74 | 0.04 | 0.58 | FALSE |