Best TWAS P=3.01e-09 · Best GWAS P=2.62e-08 conditioned to 0.0991
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | GS1-124K5.4 | 0.11 | 0.08 | lasso | 3 | 0.09 | 9.1e-06 | 4.8 | 5.2 | 2.2e-07 | 0.81 | 0.13 | 0.86 | FALSE |
| 2 | GTEx | Brain Putamen basal ganglia | GS1-124K5.4 | 0.31 | 0.32 | enet | 23 | 0.36 | 1.7e-09 | 4.8 | 5.9 | 3.0e-09 | 0.76 | 0.10 | 0.89 | TRUE |
| 3 | GTEx | Prostate | GS1-124K5.4 | 0.23 | 0.19 | lasso | 15 | 0.19 | 1.9e-05 | 4.5 | 5.1 | 3.1e-07 | 0.77 | 0.16 | 0.74 | FALSE |
| 4 | GTEx | Spleen | GS1-124K5.4 | 0.28 | 0.17 | enet | 19 | 0.23 | 1.3e-06 | 4.7 | 5.7 | 1.3e-08 | 0.71 | 0.13 | 0.85 | FALSE |
| 5 | GTEx | Thyroid | GS1-124K5.4 | 0.17 | 0.16 | lasso | 6 | 0.15 | 1.2e-11 | 4.8 | 5.2 | 1.5e-07 | 0.88 | 0.06 | 0.93 | FALSE |