Best TWAS P=5.52e-08 · Best GWAS P=8.36e-11 conditioned to 0.000331
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Coronary | ZNF514 | 0.32 | 0.20 | lasso | 8 | 0.22 | 4.3e-08 | -4.9 | 5.3 | 1.0e-07 | -0.83 | 0.15 | 0.78 | FALSE |
| 2 | GTEx | Heart Atrial Appendage | ZNF514 | 0.22 | 0.00 | enet | 19 | 0.08 | 1.2e-04 | -3.9 | 5.3 | 1.2e-07 | -0.62 | 0.05 | 0.73 | FALSE |
| 3 | GTEx | Pancreas | ZNF514 | 0.25 | 0.09 | lasso | 4 | 0.16 | 2.8e-07 | -2.4 | 5.3 | 1.2e-07 | -0.69 | 0.01 | 0.96 | FALSE |
| 4 | GTEx | Spleen | ZNF514 | 0.29 | 0.06 | enet | 10 | 0.12 | 4.8e-04 | -6.5 | 5.4 | 5.5e-08 | -0.79 | 0.01 | 0.81 | TRUE |