Best TWAS P=1.8e-17 · Best GWAS P=8.81e-22 conditioned to 0.223
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Male) | RP1-151B14.6 | 0.23 | -0.01 | lasso | 4 | 0.01 | 1.4e-01 | 8.5 | 7.6 | 3.7e-14 | 0.45 | 0.07 | 0.05 | FALSE |
| 2 | GTEx | Liver | C1QTNF6 | 0.32 | 0.18 | lasso | 4 | 0.11 | 6.4e-04 | 8.5 | 7.8 | 4.8e-15 | 0.51 | 0.25 | 0.10 | FALSE |
| 3 | GTEx | Muscle Skeletal | C1QTNF6 | 0.18 | 0.14 | lasso | 3 | 0.12 | 7.1e-12 | 8.5 | 8.5 | 1.8e-17 | 0.60 | 0.98 | 0.02 | TRUE |
| 4 | GTEx | Muscle Skeletal | RP1-151B14.6 | 0.21 | 0.14 | lasso | 4 | 0.12 | 3.0e-12 | 8.5 | 8.5 | 2.8e-17 | 0.58 | 0.98 | 0.02 | FALSE |
| 5 | GTEx | Whole Blood | C1QTNF6 | 0.18 | 0.12 | enet | 20 | 0.16 | 7.8e-15 | 8.5 | 5.2 | 1.7e-07 | 0.18 | 0.98 | 0.02 | FALSE |
| 6 | GTEx | Whole Blood | RP1-151B14.6 | 0.10 | 0.07 | lasso | 2 | 0.04 | 6.4e-05 | 8.4 | 8.4 | 3.5e-17 | 0.58 | 0.96 | 0.02 | FALSE |
| 7 | The Cancer Genome Atlas | Breast Invasive Carcinoma | C1QTNF6 | 0.05 | 0.04 | lasso | 3 | 0.04 | 5.0e-09 | -6.8 | -7.0 | 3.4e-12 | -0.82 | 0.02 | 0.98 | TRUE |
| 8 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | SSTR3 | 0.04 | 0.00 | blup | 101 | 0.02 | 6.6e-03 | -3.6 | 5.3 | 1.1e-07 | 0.74 | 0.02 | 0.64 | TRUE |