TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
High cholesterol (Self-reported)
:
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chr8:58,628,032-60,056,887
Best TWAS P=1.74e-07 · Best GWAS P=1.57e-11 conditioned to 3.5e-06
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Artery Aorta
UBXN2B
0.11
0.10
lasso
2
0.1
6.1e-06
-4.6
5.2
1.7e-07
0.55
0.10
0.78
TRUE
2
GTEx
Brain Frontal Cortex BA9
UBXN2B
0.27
0.01
lasso
4
0.0
2.4e-01
-4.6
5.2
2.2e-07
0.56
0.06
0.24
FALSE