[Hub]/) : Traits : High cholesterol (Self-reported) :

chr9:135,883,620-136,399,075

Best TWAS P=1.32e-16 · Best GWAS P=3.14e-16 conditioned to 0.000108

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 The Cancer Genome Atlas Breast Invasive Carcinoma ABO 0.07 0.08 lasso 3 0.08 5.0e-16 5.4 5.4 7.4e-08 0.63 0.18 0.82 FALSE
2 The Cancer Genome Atlas Esophageal Carcinoma ABO 0.27 0.13 lasso 2 0.11 1.8e-04 5.4 5.4 6.2e-08 0.63 0.02 0.96 FALSE
3 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma ABO 0.31 0.38 lasso 5 0.42 3.1e-26 6.3 5.9 3.8e-09 0.54 0.00 1.00 FALSE
4 The Cancer Genome Atlas Liver Hepatocellular Carcinoma ABO 0.23 0.23 lasso 2 0.24 2.2e-11 6.3 6.2 4.8e-10 0.53 0.00 1.00 FALSE
5 The Cancer Genome Atlas Lung Adenocarcinoma ABO 0.21 0.25 lasso 5 0.25 2.1e-29 5.4 5.4 5.5e-08 0.59 0.02 0.98 FALSE
6 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma ABO 0.28 0.22 lasso 8 0.22 1.2e-14 5.4 5.4 5.5e-08 0.63 0.01 0.99 FALSE
7 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma ABO 0.23 0.23 lasso 3 0.23 2.0e-09 5.4 5.6 2.2e-08 0.61 0.01 0.99 FALSE
8 The Cancer Genome Atlas Rectum Adenocarcinoma ABO 0.48 0.23 enet 10 0.27 4.7e-07 6.3 6.5 7.5e-11 0.65 0.00 0.98 FALSE
9 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma ABO 0.23 0.07 blup 44 0.12 4.3e-04 6.3 8.3 1.3e-16 0.62 0.00 0.79 TRUE