Best TWAS P=3.79e-11 · Best GWAS P=2.32e-13 conditioned to 0.00341
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | HNF1A | 0.19 | 0.13 | lasso | 15 | 0.12 | 1.7e-14 | 5.9 | 6.2 | 6.5e-10 | 0.68 | 0.86 | 0.14 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | C12orf27 | 0.03 | 0.01 | lasso | 4 | 0.01 | 1.1e-02 | 6.7 | 6.6 | 3.8e-11 | 0.70 | 0.04 | 0.45 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | C12orf43 | 0.06 | 0.03 | lasso | 4 | 0.02 | 6.9e-03 | -5.8 | -5.7 | 1.1e-08 | -0.62 | 0.06 | 0.61 | TRUE |