Best TWAS P=3.29e-08 · Best GWAS P=1.87e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | MLXIPL | 0.11 | 0.07 | enet | 16 | 0.07 | 1.6e-06 | -4.9 | -5.3 | 1.4e-07 | 0.93 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | MLXIPL | 0.13 | 0.06 | enet | 6 | 0.09 | 2.2e-07 | -5.6 | -5.3 | 1.3e-07 | 0.93 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | MLXIPL | 0.11 | 0.11 | lasso | 3 | 0.06 | 2.7e-04 | -5.6 | -5.5 | 3.3e-08 | 0.99 | 0.00 | 0.99 | TRUE |
| 4 | GTEx | Skin Sun Exposed Lower leg | MLXIPL | 0.12 | 0.09 | lasso | 4 | 0.06 | 6.1e-06 | -5.5 | -5.5 | 3.9e-08 | 0.96 | 0.01 | 0.99 | FALSE |
| 5 | GTEx | Thyroid | MLXIPL | 0.23 | 0.14 | lasso | 7 | 0.15 | 2.1e-11 | -4.9 | -5.5 | 4.9e-08 | 0.95 | 0.01 | 0.99 | FALSE |