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Traits
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Medication: Allopurinol
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chr7:72,674,074-73,738,067
Best TWAS P=3.29e-08 · Best GWAS P=1.87e-08 conditioned to 1
72.8M
73M
73.2M
73.4M
73.6M
73.8M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
GTEx
Skin Not Sun Exposed Suprapubic
MLXIPL
0.11
0.11
lasso
3
0.06
2.7e-04
-5.6
-5.5
3.3e-08
0.99
0.00
0.99
TRUE
4
GTEx
Skin Sun Exposed Lower leg
MLXIPL
0.12
0.09
lasso
4
0.06
6.1e-06
-5.5
-5.5
3.9e-08
0.96
0.01
0.99
FALSE
5
GTEx
Thyroid
MLXIPL
0.23
0.14
lasso
7
0.15
2.1e-11
-4.9
-5.5
4.9e-08
0.95
0.01
0.99
FALSE
2
GTEx
Cells Transformed fibroblasts
MLXIPL
0.13
0.06
enet
6
0.09
2.2e-07
-5.6
-5.3
1.3e-07
0.93
0.01
0.99
FALSE
1
GTEx
Adipose Subcutaneous
MLXIPL
0.11
0.07
enet
16
0.07
1.6e-06
-4.9
-5.3
1.4e-07
0.93
0.01
0.99
FALSE