[Hub]/) : Traits : Sitting height :

chr6:44,079,216-46,043,561

Best TWAS P=2.93e-30 · Best GWAS P=3.46e-31 conditioned to 0.00234

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SUPT3H 0.33 0.26 enet 43 0.44 2.5e-59 -5.1 -6.8 1.1e-11 -0.60 1.00 0.00 FALSE
2 GTEx Adipose Visceral Omentum SUPT3H 0.27 0.10 lasso 7 0.06 3.4e-04 10.9 -11.4 2.9e-30 -0.91 0.02 0.98 TRUE
3 GTEx Artery Tibial SUPT3H 0.13 0.01 enet 21 0.02 1.9e-02 -5.0 -8.9 3.8e-19 -0.64 0.08 0.88 FALSE
4 GTEx Brain Cortex SUPT3H 0.28 0.01 lasso 7 0.01 2.1e-01 -5.3 -5.2 2.1e-07 -0.56 0.21 0.26 FALSE
5 GTEx Cells EBV-transformed lymphocytes SUPT3H 0.20 0.08 lasso 6 0.10 3.0e-04 10.8 -9.8 1.6e-22 -0.83 0.20 0.53 FALSE
6 GTEx Cells Transformed fibroblasts SUPT3H 0.15 0.10 lasso 4 0.13 8.8e-10 10.9 -8.7 4.7e-18 -0.86 0.06 0.94 FALSE
7 GTEx Esophagus Gastroesophageal Junction SUPT3H 0.27 0.01 lasso 3 0.00 2.7e-01 -7.2 -7.1 1.1e-12 -0.48 0.09 0.31 FALSE
8 GTEx Esophagus Mucosa SUPT3H 0.08 0.09 lasso 3 0.08 6.4e-06 10.9 -11.1 7.2e-29 -0.93 0.02 0.98 FALSE
9 GTEx Esophagus Muscularis SUPT3H 0.10 0.03 enet 20 0.02 1.3e-02 -7.2 -7.0 1.8e-12 -0.57 0.14 0.42 FALSE
10 GTEx Lung SUPT3H 0.10 0.06 enet 21 0.03 1.3e-03 10.7 -10.7 6.4e-27 -0.84 0.07 0.92 FALSE
11 GTEx Nerve Tibial SUPT3H 0.17 0.12 lasso 5 0.10 2.2e-07 10.7 -10.8 5.7e-27 -0.96 0.04 0.96 FALSE
12 GTEx Pancreas SUPT3H 0.11 0.07 lasso 2 0.05 3.6e-03 11.3 -11.3 1.5e-29 -0.98 0.02 0.95 FALSE
13 GTEx Pituitary SUPT3H 0.26 0.08 lasso 6 0.05 1.8e-02 -5.1 -5.7 1.6e-08 -0.59 0.09 0.25 FALSE
14 GTEx Skin Sun Exposed Lower leg SUPT3H 0.07 0.03 lasso 5 0.04 4.2e-04 10.7 -9.6 1.0e-21 -0.85 0.04 0.92 FALSE
15 GTEx Spleen SUPT3H 0.32 0.06 enet 12 0.11 9.5e-04 10.0 -10.8 3.4e-27 -0.80 0.13 0.63 FALSE
16 GTEx Testis SUPT3H 0.30 0.16 lasso 7 0.17 6.7e-08 -4.7 -6.2 7.7e-10 -0.59 0.81 0.19 FALSE
17 GTEx Thyroid SUPT3H 0.29 0.07 lasso 8 0.07 7.3e-06 -5.6 -7.0 1.9e-12 -0.37 0.51 0.46 FALSE
18 METSIM Adipose SUPT3H 0.11 0.04 bslmm 657 0.06 2.7e-09 10.8 -7.4 1.7e-13 -0.70 0.12 0.88 FALSE
19 NTR Blood SUPT3H 0.03 0.02 lasso 7 0.02 1.9e-07 -6.8 -8.1 7.5e-16 -0.78 0.97 0.03 FALSE
20 ROSMAP Brain Pre-frontal Cortex SUPT3H 0.15 0.13 blup 643 0.17 3.4e-21 -4.6 -5.3 1.2e-07 -0.65 1.00 0.00 FALSE
21 YFS Blood SUPT3H 0.06 0.09 lasso 13 0.12 2.2e-36 10.7 -9.4 8.0e-21 -0.89 0.18 0.82 FALSE
22 The Cancer Genome Atlas Breast Invasive Carcinoma SUPT3H 0.02 0.01 blup 191 0.01 3.0e-03 10.9 -10.6 2.4e-26 -0.94 0.03 0.96 FALSE
23 The Cancer Genome Atlas Colon Adenocarcinoma SUPT3H 0.08 0.01 blup 191 0.05 1.0e-03 10.9 -10.9 8.3e-28 -0.83 0.02 0.93 FALSE
24 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SUPT3H 0.04 0.01 blup 191 0.02 6.5e-03 -5.1 -9.0 2.9e-19 -0.83 0.04 0.94 FALSE
25 The Cancer Genome Atlas Brain Lower Grade Glioma SUPT3H 0.07 0.05 enet 12 0.08 1.1e-09 -4.7 -9.1 8.3e-20 -0.84 0.19 0.81 FALSE
26 The Cancer Genome Atlas Lung Adenocarcinoma SUPT3H 0.03 0.03 lasso 2 0.02 8.9e-04 10.9 -10.7 6.8e-27 -0.92 0.06 0.81 FALSE
27 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma SUPT3H 0.12 0.08 blup 191 0.09 2.8e-04 11.1 -11.4 5.9e-30 -0.92 0.04 0.95 FALSE
28 The Cancer Genome Atlas Stomach Adenocarcinoma SUPT3H 0.05 0.01 blup 191 0.00 1.4e-01 -4.1 -8.2 2.1e-16 -0.77 0.10 0.26 FALSE
29 The Cancer Genome Atlas Thyroid Carcinoma SUPT3H 0.06 0.04 lasso 4 0.05 2.1e-05 10.8 -11.1 1.3e-28 -0.87 0.05 0.94 FALSE