Best TWAS P=1.65e-08 · Best GWAS P=1.19e-08 conditioned to 0.247
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Heart Left Ventricle | RP11-152F13.3 | 0.16 | 0.05 | lasso | 5 | 0.06 | 4.0e-04 | -5.3 | 5.4 | 6.7e-08 | -0.87 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Thyroid | GOLGA6L9 | 0.12 | 0.02 | lasso | 4 | 0.01 | 6.5e-02 | -5.7 | -5.4 | 7.3e-08 | 0.98 | 0.00 | 0.96 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | RP13-996F3.3 | 0.67 | 0.23 | enet | 76 | 0.42 | 2.6e-59 | -5.7 | 5.2 | 2.1e-07 | -0.70 | 0.00 | 1.00 | FALSE |
| 4 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | LOC80154 | 0.16 | 0.10 | lasso | 2 | 0.09 | 5.0e-08 | -5.6 | 5.4 | 5.4e-08 | -0.95 | 0.00 | 1.00 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | LOC80154 | 0.08 | 0.06 | blup | 8 | 0.06 | 1.5e-07 | -5.6 | 5.1 | 3.0e-07 | -0.92 | 0.00 | 1.00 | FALSE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | LOC80154 | 0.09 | 0.06 | lasso | 3 | 0.06 | 1.4e-07 | -5.6 | 5.4 | 6.0e-08 | -0.94 | 0.00 | 1.00 | FALSE |
| 7 | The Cancer Genome Atlas | Stomach Adenocarcinoma | LOC80154 | 0.11 | 0.06 | lasso | 2 | 0.05 | 8.5e-05 | -5.6 | 5.6 | 1.6e-08 | -0.94 | 0.00 | 0.98 | TRUE |
| 8 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | LOC80154 | 0.13 | 0.08 | lasso | 1 | 0.06 | 4.9e-03 | -5.6 | 5.6 | 2.6e-08 | -0.95 | 0.00 | 0.84 | FALSE |
| 9 | The Cancer Genome Atlas | Thyroid Carcinoma | LOC80154 | 0.04 | 0.03 | lasso | 2 | 0.02 | 5.7e-03 | -5.6 | 5.3 | 9.1e-08 | -0.94 | 0.00 | 0.91 | FALSE |