[Hub]/) : Traits : Body mass index (BMI) :

chr11:130,038,487-131,476,599

Best TWAS P=1.57e-10 · Best GWAS P=3.31e-11 conditioned to 0.00621

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous SNX19 0.21 0.15 enet 24 0.16 2.3e-13 5.0 -6.2 5.7e-10 0.73 0.68 0.32 FALSE
2 GTEx Adipose Visceral Omentum SNX19 0.22 0.10 lasso 7 0.10 8.0e-06 5.0 -5.8 7.5e-09 0.63 0.36 0.63 FALSE
3 GTEx Adrenal Gland SNX19 0.24 0.16 lasso 4 0.06 3.2e-03 4.9 -5.7 1.5e-08 0.58 0.44 0.53 FALSE
4 GTEx Artery Tibial SNX19 0.22 0.14 lasso 6 0.20 1.5e-15 -3.0 -5.3 9.2e-08 0.57 0.49 0.51 FALSE
5 GTEx Brain Caudate basal ganglia SNX19 0.33 0.12 lasso 5 0.12 2.8e-04 5.1 -6.0 1.9e-09 0.57 0.20 0.62 FALSE
6 GTEx Brain Cortex SNX19 0.36 0.12 lasso 7 0.16 3.3e-05 4.7 -5.6 1.8e-08 0.53 0.15 0.74 FALSE
7 GTEx Brain Frontal Cortex BA9 SNX19 0.41 0.20 lasso 7 0.37 7.1e-11 -6.0 -6.0 2.3e-09 0.52 0.21 0.72 FALSE
8 GTEx Brain Hippocampus SNX19 0.24 0.07 enet 17 0.16 1.8e-04 -6.0 -5.5 2.9e-08 0.49 0.13 0.60 FALSE
9 GTEx Brain Hypothalamus SNX19 0.32 0.04 lasso 5 0.13 7.4e-04 4.6 -6.1 1.0e-09 0.67 0.09 0.83 FALSE
10 GTEx Esophagus Gastroesophageal Junction SNX19 0.35 0.07 enet 29 0.22 1.7e-08 6.2 -5.2 2.1e-07 0.70 0.07 0.92 FALSE
11 GTEx Esophagus Muscularis SNX19 0.31 0.18 enet 23 0.25 1.2e-15 4.9 -6.4 1.6e-10 0.76 0.29 0.71 TRUE
12 GTEx Heart Atrial Appendage SNX19 0.50 0.20 enet 32 0.32 4.9e-15 -6.5 -6.1 9.0e-10 0.83 0.02 0.98 FALSE
13 GTEx Heart Left Ventricle SNX19 0.21 0.06 lasso 4 0.05 9.7e-04 5.0 -5.8 4.9e-09 0.59 0.23 0.70 FALSE
14 GTEx Pancreas SNX19 0.35 0.12 enet 19 0.27 1.2e-11 5.0 -5.3 1.4e-07 0.63 0.32 0.68 FALSE
15 GTEx Pancreas RP11-890B15.3 0.16 0.02 lasso 2 0.01 1.9e-01 -6.3 -6.1 1.0e-09 0.60 0.12 0.69 FALSE
16 GTEx Stomach SNX19 0.39 0.29 lasso 13 0.27 2.0e-13 5.0 -6.1 1.4e-09 0.70 0.81 0.19 FALSE
17 GTEx Testis SNX19 0.59 0.25 enet 24 0.38 7.1e-18 -6.3 -6.1 9.0e-10 0.68 0.10 0.90 FALSE
18 METSIM Adipose SNX19 0.16 0.20 lasso 2 0.20 1.5e-28 5.3 -5.3 1.2e-07 0.54 0.95 0.05 FALSE
19 ROSMAP Brain Pre-frontal Cortex SNX19 0.41 0.49 lasso 6 0.51 2.7e-75 5.3 -6.0 1.9e-09 0.61 0.95 0.05 FALSE
20 The Cancer Genome Atlas Esophageal Carcinoma SNX19 0.15 0.08 lasso 6 0.12 1.4e-04 5.3 -5.8 5.2e-09 0.66 0.23 0.47 FALSE
21 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SNX19 0.11 0.19 enet 15 0.24 3.2e-26 5.3 -5.9 3.3e-09 0.61 0.90 0.10 FALSE
22 The Cancer Genome Atlas Brain Lower Grade Glioma SNX19 0.17 0.20 lasso 6 0.23 9.8e-26 5.3 -5.7 9.4e-09 0.61 0.86 0.14 FALSE
23 The Cancer Genome Atlas Pancreatic Adenocarcinoma SNX19 0.06 0.04 blup 100 0.06 1.3e-03 4.7 -6.2 6.5e-10 0.76 0.04 0.61 FALSE