Best TWAS P=1e-08 · Best GWAS P=3.44e-09 conditioned to 0.00094
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | BTD | 0.07 | 0.09 | lasso | 3 | 0.07 | 1.2e-09 | 5.2 | 5.4 | 8.5e-08 | -0.55 | 0.09 | 0.91 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | AC090945.1 | 0.10 | 0.12 | lasso | 7 | 0.11 | 2.8e-14 | 5.4 | 5.7 | 1.0e-08 | -0.55 | 0.04 | 0.95 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | BTD | 0.07 | 0.04 | enet | 9 | 0.04 | 1.6e-03 | -5.9 | 5.7 | 1.5e-08 | -0.81 | 0.00 | 0.87 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | BTD | 0.04 | 0.02 | lasso | 3 | 0.02 | 6.5e-03 | 5.3 | 5.5 | 3.6e-08 | -0.63 | 0.01 | 0.69 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | BTD | 0.08 | 0.12 | lasso | 4 | 0.10 | 5.0e-10 | 4.8 | 5.1 | 2.7e-07 | -0.47 | 0.20 | 0.80 | FALSE |