Best TWAS P=9.95e-09 · Best GWAS P=5.95e-06 conditioned to 0.0139
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Breast Mammary Tissue (Male) | SNORD68 | 0.12 | 0.00 | enet | 28 | 0.03 | 8.2e-02 | -3.7 | -5.7 | 9.9e-09 | 0.40 | 0.01 | 0.05 | TRUE |
2 | GTEx | Cells Transformed fibroblasts | DBNDD1 | 0.32 | 0.20 | enet | 36 | 0.20 | 1.2e-14 | -4.1 | -5.7 | 1.2e-08 | 0.68 | 0.03 | 0.83 | FALSE |
3 | GTEx | Colon Transverse | DBNDD1 | 0.62 | 0.40 | enet | 40 | 0.44 | 1.2e-22 | -4.1 | -5.1 | 3.0e-07 | 0.65 | 0.03 | 0.83 | FALSE |
4 | GTEx | Heart Atrial Appendage | DBNDD1 | 0.52 | 0.29 | enet | 27 | 0.27 | 9.8e-13 | -4.1 | -5.5 | 3.5e-08 | 0.67 | 0.03 | 0.83 | FALSE |
5 | GTEx | Pancreas | DBNDD1 | 0.26 | 0.16 | enet | 15 | 0.18 | 5.6e-08 | -4.1 | -5.2 | 2.2e-07 | 0.58 | 0.03 | 0.76 | FALSE |