Best TWAS P=1.28e-07 · Best GWAS P=4.93e-07 conditioned to 0.000686
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | GSTM1 | 0.51 | 0.05 | blup | 434 | 0.26 | 1.4e-33 | -2 | 5.3 | 1.3e-07 | 0.35 | 0.65 | 0.03 | TRUE |
| 2 | YFS | Blood | GNAI3 | 0.43 | 0.44 | lasso | 11 | 0.50 | 2.3e-192 | 5 | -5.2 | 1.7e-07 | -0.95 | 0.01 | 0.99 | FALSE |