TWAS
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Usage
Models
Genes
Traits
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Traits
:
Whole body fat mass
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chr20:49,975,801-52,810,143
Best TWAS P=8.69e-12 · Best GWAS P=2.88e-15 conditioned to 2.74e-05
50M
50.5M
51M
51.5M
52M
52.5M
0
5
10
15
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Artery Tibial
ZFP64
0.1
0.03
lasso
4
0.06
3.4e-05
2.3
6.8
8.7e-12
-0.75
0.02
0.96
TRUE
2
YFS
Blood
TSHZ2
0.1
0.03
bslmm
798
0.07
2.8e-22
-7.1
5.6
2.0e-08
-0.64
0.01
0.99
FALSE