TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Whole body fat mass
:
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→
chr3:14,947,539-16,612,886
Best TWAS P=1.65e-07 · Best GWAS P=4.26e-07 conditioned to 0.406
15M
15.2M
15.4M
15.6M
15.8M
16M
16.2M
16.4M
16.6M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
ROSMAP
Brain Pre-frontal Cortex
AC090945.1
0.10
0.12
lasso
7
0.11
2.8e-14
4.9
5.2
1.7e-07
0.89
0.03
0.96
TRUE
1
ROSMAP
Brain Pre-frontal Cortex
BTD
0.07
0.09
lasso
3
0.07
1.2e-09
5.0
5.2
2.4e-07
0.78
0.01
0.98
FALSE
3
The Cancer Genome Atlas
Prostate Adenocarcinoma
BTD
0.04
0.02
lasso
3
0.02
6.5e-03
5.0
5.1
3.1e-07
0.87
0.01
0.72
FALSE