Best TWAS P=1.65e-07 · Best GWAS P=4.26e-07 conditioned to 0.406
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | BTD | 0.07 | 0.09 | lasso | 3 | 0.07 | 1.2e-09 | 5.0 | 5.2 | 2.4e-07 | 0.78 | 0.01 | 0.98 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | AC090945.1 | 0.10 | 0.12 | lasso | 7 | 0.11 | 2.8e-14 | 4.9 | 5.2 | 1.7e-07 | 0.89 | 0.03 | 0.96 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | BTD | 0.04 | 0.02 | lasso | 3 | 0.02 | 6.5e-03 | 5.0 | 5.1 | 3.1e-07 | 0.87 | 0.01 | 0.72 | FALSE |