TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Whole body fat mass
:
←
→
chr3:140,350,567-141,867,638
Best TWAS P=3.47e-23 · Best GWAS P=4e-23 conditioned to 1
140.4M
140.6M
140.8M
141M
141.2M
141.4M
141.6M
141.8M
0
5
10
15
20
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Adipose Subcutaneous
ZBTB38
0.08
0.04
lasso
4
0.03
8.1e-04
9.9
9.9
3.5e-23
0.98
0.01
0.99
TRUE
5
The Cancer Genome Atlas
Soft Tissue Sarcoma
ZBTB38
0.04
0.03
lasso
3
0.04
3.0e-03
8.9
9.6
1.1e-21
0.59
0.04
0.41
TRUE
2
GTEx
Testis
ZBTB38
0.14
0.06
lasso
8
0.05
2.8e-03
8.7
9.1
1.2e-19
0.60
0.24
0.62
FALSE
4
NTR
Blood
ZBTB38
0.03
0.01
lasso
3
0.01
2.2e-05
9.8
8.7
5.3e-18
0.88
0.01
0.99
FALSE
3
GTEx
Thyroid
ZBTB38
0.11
0.03
enet
32
0.04
2.9e-04
7.0
8.1
4.4e-16
0.62
0.07
0.92
FALSE