[Hub]/) : Traits : Whole body fat mass :

chr9:102,162,230-103,803,109

Best TWAS P=5.5e-10 · Best GWAS P=4.55e-10 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta INVS 0.15 0.10 enet 19 0.12 4.9e-07 6.2 5.4 7.8e-08 0.86 0.02 0.98 FALSE
2 GTEx Cells Transformed fibroblasts INVS 0.16 0.10 enet 17 0.17 8.0e-13 6.2 5.5 5.0e-08 0.84 0.01 0.99 FALSE
3 GTEx Esophagus Muscularis INVS 0.21 0.16 lasso 5 0.22 8.9e-14 6.2 5.3 1.1e-07 0.85 0.01 0.99 FALSE
4 GTEx Heart Atrial Appendage INVS 0.08 0.03 lasso 3 0.04 4.9e-03 -4.6 5.2 1.5e-07 0.81 0.06 0.88 FALSE
5 GTEx Heart Left Ventricle INVS 0.11 0.05 enet 15 0.04 2.6e-03 2.1 5.2 1.6e-07 0.70 0.04 0.85 FALSE
6 GTEx Muscle Skeletal INVS 0.12 0.03 lasso 10 0.10 1.3e-09 6.2 5.4 6.3e-08 0.82 0.02 0.98 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic TEX10 0.10 0.09 lasso 4 0.10 3.1e-06 4.1 5.3 1.1e-07 0.68 0.04 0.96 FALSE
8 GTEx Skin Sun Exposed Lower leg INVS 0.19 0.06 enet 30 0.11 1.5e-09 6.2 5.6 2.3e-08 0.74 0.01 0.99 FALSE
9 GTEx Skin Sun Exposed Lower leg TEX10 0.27 0.27 lasso 8 0.28 7.0e-23 6.2 6.1 1.3e-09 0.77 0.01 0.99 FALSE
10 YFS Blood INVS 0.15 0.14 lasso 7 0.24 1.4e-77 2.3 5.2 2.3e-07 0.77 0.04 0.96 FALSE
11 The Cancer Genome Atlas Bladder Urothelial Carcinoma INVS 0.27 0.05 lasso 8 0.13 3.4e-11 4.3 5.2 2.4e-07 0.74 0.06 0.94 FALSE
12 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma INVS 0.10 0.03 blup 107 0.07 4.0e-04 5.9 5.2 2.3e-07 0.63 0.03 0.90 FALSE
13 The Cancer Genome Atlas Lung Adenocarcinoma INVS 0.08 0.06 blup 106 0.07 7.0e-09 -4.1 5.4 6.3e-08 0.84 0.43 0.57 FALSE
14 The Cancer Genome Atlas Lung Squamous Cell Carcinoma INVS 0.09 0.02 enet 11 0.04 4.0e-05 4.3 5.4 5.9e-08 0.71 0.03 0.69 FALSE
15 The Cancer Genome Atlas Pancreatic Adenocarcinoma INVS 0.16 0.12 enet 8 0.08 2.8e-04 5.9 6.2 5.5e-10 0.99 0.01 0.98 TRUE