Best TWAS P=7.31e-14 · Best GWAS P=3.39e-70 conditioned to 1.92e-63
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Visceral Omentum | LEMD3 | 0.14 | 0.05 | lasso | 8 | 0.05 | 1.1e-03 | -3.9 | -5.6 | 2.7e-08 | 0.11 | 0.46 | 0.04 | TRUE |
2 | GTEx | Heart Atrial Appendage | RBMS1P1 | 0.17 | 0.03 | lasso | 11 | 0.04 | 7.3e-03 | 10.1 | -7.5 | 7.3e-14 | -0.40 | 0.06 | 0.41 | TRUE |
3 | GTEx | Nerve Tibial | LEMD3 | 0.12 | 0.14 | enet | 13 | 0.16 | 2.0e-11 | -4.3 | -5.5 | 4.0e-08 | 0.11 | 1.00 | 0.00 | FALSE |