Best TWAS P=8.27e-10 · Best GWAS P=4.55e-09 conditioned to 4.73e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | C1orf54 | 0.06 | 0.02 | enet | 13 | 0.02 | 1.2e-05 | 5.1 | -6.1 | 8.3e-10 | -0.14 | 0.00 | 0.97 | TRUE |
| 2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | C1orf54 | 0.04 | 0.04 | lasso | 2 | 0.03 | 2.0e-04 | 5.1 | -5.2 | 1.9e-07 | -0.47 | 0.00 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | MRPS21 | 0.13 | 0.13 | enet | 10 | 0.13 | 1.7e-14 | -4.0 | 5.5 | 4.7e-08 | 0.38 | 0.06 | 0.86 | FALSE |